Providence research from Washington locations.

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Submissions from 2024

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Endoscopic ultrasound-guided portal pressure gradient measurement: a systematic review and meta-analysis., Banreet Singh Dhindsa, Kyaw Min Tun, Alexandra Fiedler, Smit Deliwala, Syed Mohsin Saghir, Kyle Scholten, Daryl Ramai, Mohit Girotra, Saurabh Chandan, Amaninder Dhaliwal, Ishfaq Bhat, Shailender Singh, and Douglas G Adler

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Impact of Self-Reported Loss of Balance and Gait Disturbance on Outcomes following Adult Spinal Deformity Surgery., Bassel G Diebo, Daniel Alsoof, Renaud Lafage, Mohammad Daher, Mariah Balmaceno-Criss, Peter G Passias, Christopher P Ames, Christopher I Shaffrey, Douglas C Burton, Vedat Deviren, Breton G Line, Alex Soroceanu, David Kojo Hamilton, Eric O Klineberg, Gregory M Mundis, Han Jo Kim, Jeffrey L Gum, Justin S Smith, Juan S Uribe, Khaled M Kebaish, Munish C Gupta, Pierce D Nunley, Robert K Eastlack, Richard Hostin, Themistocles S Protopsaltis, Lawrence G Lenke, Robert A Hart, Frank J Schwab, Shay Bess, Virginie Lafage, Alan H Daniels, and ISSG

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Metagenomic estimation of dietary intake from human stool., Christian Diener and Sean M Gibbons

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Cannabis Use Disorder Trends and Health Care Utilization After Cervical and Lumbar Spine Fusions., Nicholas Dietz, Victoria Alkin, Nitin Agarwal, Mayur Sharma, Brent Garrison Oxford, Dengzhi Wang, Beatrice Ugiliweneza, Jersey Mettille, Maxwell Boakye, and Doniel Drazin

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A Suicide Prevention Digital Technology for Individuals Experiencing an Acute Suicide Crisis in Emergency Departments: Naturalistic Observational Study of Real-World Acceptability, Feasibility, and Safety., Linda A Dimeff, Kelly Koerner, Kandi Heard, Allison K Ruork, Angela Kelley-Brimer, Suzanne T Witterholt, Mary Beth Lardizabal, Joseph R Clubb, Julie McComish, Arpan Waghray, Roger Dowdy, Sara Asad-Pursley, Maria Ilac, Hannah Lawrence, Frank Zhou, and Blair Beadnell

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Clinicopathologic Characterization of 2 Individuals With, Kimiko Domoto-Reilly, B Jane Distad, Danny E Miller, Yi-Han Lin, David Ivanick, Andrew S Warren, Suman Jayadev, and Caitlin S Latimer

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The relationship between 11 different polygenic longevity scores, parental lifespan, and disease diagnosis in the UK Biobank., Janith Don, Andrew J Schork, Gwênlyn Glusman, Noa Rappaport, Steve R Cummings, David Duggan, Anish Raju, Kajsa-Lotta Georgii Hellberg, Sophia Gunn, Stefano Monti, Thomas Perls, Jodi Lapidus, Laura H Goetz, Paola Sebastiani, and Nicholas J Schork

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Development and validation of metrics for a new RAPN training model., Rui Jorge Dos Santos Almeida Farinha, Adele Piro, Angelo Mottaran, Marco Paciotti, Stefano Puliatti, Alberto Breda, James Porter, Ben Van Cleynenbreugel, Jos Vander Sloten, Alexandre Mottrie, RAPN-Delphi Surgeons Group, and Anthony G Gallagher

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Guardians of the Catheters, Interprofessional Collaboration Reduced CAUTI Rates at PHFH, Dawn Doud, Angela Shemwell, Stephanie Brown, Tobi Bryan, Georgia Gauron, Tasha Anisimov, Peter Weitzman, Emma Peterson, and Tiffanie Rampley

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Implementation of the AHRQ Nurse Bedside Shift Report on a Progressive Care Unit (PCU), Dawn Doud, Angie Shemwell, Sherri Butcher, Crystal Maxey, and Tanner Doyle

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Elective Single-Level Primary Anterior Cervical Decompression and Fusion for Degenerative Spondylotic Cervical Myelopathy is Associated With Decreased Resource Utilization Versus Posterior Cervical Decompression and Fusion., Jerry Y Du, Karim Shafi, Collin W Blackburn, Jens R Chapman, Nicholas U Ahn, Randall E Marcus, and Todd J Albert

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Resource Utilization following Anterior Versus Posterior Cervical Decompression and Fusion for Acute Central Cord Syndrome., Jerry Y Du, Karim Shafi, Collin W Blackburn, Jens R Chapman, Nicholas U Ahn, Randall E Marcus, and Todd J Albert

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Comment on: Effect of gender and age on bDMARD efficacy for axial spondyloarthritis patients: a meta-analysis of randomized controlled trials., Lihi Eder, Jordi Pardo Pardo, Philip Mease, and Lianne S Gensler

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Naloxone: From Legislation to Distribution, Kailyn Elliot, Emily Stewart, and John Delfeld

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Diabetic Kidney Disease Prevention Care Model Development., Nuha A ElSayed, Raveendhara R Bannuru, George Bakris, Joan Bardsley, Ian H de Boer, Robert A Gabbay, Janet Gockerman, Rozalina G McCoy, Elaine McCracken, Joshua J Neumiller, Scott J Pilla, and Connie M Rhee

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Effects of empagliflozin on progression of chronic kidney disease: a prespecified secondary analysis from the empa-kidney trial., EMPA-KIDNEY Collaborative Group and Katherine Tuttle (EMPA-KIDNEY Collaborative Group)

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Impact of primary kidney disease on the effects of empagliflozin in patients with chronic kidney disease: secondary analyses of the EMPA-KIDNEY trial., EMPA-KIDNEY Collaborative Group and Katherine Tuttle (EMPA-KIDNEY Collaborative Group)

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Effects of empagliflozin on progression of chronic kidney disease: a prespecified secondary analysis from the empa-kidney trial., EMPA-KIDNEY Collaborative Group and Katherine Tuttle

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Impact of primary kidney disease on the effects of empagliflozin in patients with chronic kidney disease: secondary analyses of the EMPA-KIDNEY trial., EMPA-KIDNEY Collaborative Group and Katherine Tuttle

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Differentiation of Prior SARS-CoV-2 Infection and Postacute Sequelae by Standard Clinical Laboratory Measurements in the RECOVER Cohort., Kristine M Erlandson, Linda N Geng, Caitlin A Selvaggi, Tanayott Thaweethai, Peter Chen, Nathan B Erdmann, Jason D Goldman, Timothy J Henrich, Mady Hornig, Elizabeth W Karlson, Stuart D Katz, C Kim, Sushma K Cribbs, Adeyinka O Laiyemo, Rebecca Letts, Janet Y Lin, Jai Marathe, Sairam Parthasarathy, Thomas F Patterson, Brittany D Taylor, Elizabeth R Duffy, Monika Haack, Boris Julg, Gabrielle Maranga, Carla Hernandez, Nora G Singer, Jenny Han, Priscilla Pemu, Hassan Brim, Hassan Ashktorab, Alexander W Charney, Juan Wisnivesky, Jenny J Lin, Helen Y Chu, Minjoung Go, Upinder Singh, Emily B Levitan, Paul A Goepfert, Janko Ž Nikolich, Harvey Hsu, Michael J Peluso, J Daniel Kelly, Megumi J Okumura, Valerie J Flaherman, John G Quigley, Jerry A Krishnan, Mary Beth Scholand, Rachel Hess, Torri D Metz, Maged M Costantine, Dwight J Rouse, Barbara S Taylor, Mark P Goldberg, Gailen D Marshall, Jeremy Wood, David Warren, Leora Horwitz, Andrea S Foulkes, Grace A McComsey, and RECOVER-Adult Cohort

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A Retrospective Multicenter Study of Operating Room Extubation and Extubation Timing following Cardiac Surgery., Eric W Etchill, Xiaoting Wu, Diane Alejo, Clifford E Fonner, Carol Ling, Neil Worrall, Eric Lehr, Francis Pagani, Terri Haber, Patty Theurer, Jeannie Collins-Brandon, Ravi Hira, James Brevig, Erika Mallory, Charles Maynard, Donald S Likosky, Glenn J R Whitman, and IMPROVE Network

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A metabolite-based liquid biopsy for detection of ovarian cancer., Johannes F Fahrmann, Seyyed Mahmood Ghasemi, Chae Y Han, Ranran Wu, Jennifer B Dennison, Jody Vykoukal, Joseph Celestino, Karen Lu, Zhen Lu, Charles Drescher, Kim-Anh Do, Samir Hanash, Robert C Bast, and Ehsan Irajizad

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Differences in nutritional profile by chronotype among 12-h day shift and night shift nurses., Rachel Faulkner, Teresa Rangel, Rebecca Penders, Trisha Saul, Ross Bindler, Lindsey Miller, and Marian Wilson

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Phase 2 Trial of Deucravacitinib in Psoriatic Arthritis: Biomarkers Associated With Disease Activity, Pharmacodynamics, and Clinical Responses., Oliver FitzGerald, Dafna D Gladman, Philip Mease, Christopher Ritchlin, Josef S Smolen, Lu Gao, Yanhua Hu, Miroslawa Nowak, Subhashis Banerjee, and Ian Catlett

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Frontline Leadership: Nurses in Special Pathogens Preparedness and Response., Jade B Flinn, Christa Arguinchona, Angela Vasa, Sharon Vanairsdale Carrasco, Iris Agreiter, Stefan Boxnick, Benjamin Stadtmann, and Patricia Ann Tennill

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Comparison of the transcriptome, lipidome, and c-di-GMP production between BCG?BCG1419c and BCG, with Mincle- and Myd88-dependent induction of proinflammatory cytokines in murine macrophages., Mario Alberto Flores-Valdez, Eliza J R Peterson, Michel de Jesús Aceves-Sánchez, Nitin S Baliga, Yasu S Morita, Ian L Sparks, Deepak Kumar Saini, Rahul Yadav, Roland Lang, Dulce Mata-Espinosa, Juan Carlos León-Contreras, and Rogelio Hernández-Pando

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Designing Effective Mentorship for Underrepresented Faculty in Academic Medicine., Kathryn Fraser, Syeachia N Dennis, Cynthia Kim, George W Saba, Jessica Guh, Cesar A Gonzalez, and Trescott Shamlou

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Healthy Sex: Contraception, Sexually Transmitted Infections, Media, Consent, and Confidentiality., Erin Fredrickson

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Implementation of Charting Guidelines: The Impact on a Telemetry Unit, McKenna Freed and Kai Stein

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The authors reply., Winston W S Fung, Valerie A Luyckx, Katherine R Tuttle, and Writing team and the World Kidney Day Joint Steering Committee

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The authors reply., Winston W S Fung, Valerie A Luyckx, Katherine R Tuttle, and World Kidney Day Joint Steering Committee

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Left atrial appendage occlusion needs lifetime management not lifetime medications., Sameer Gafoor and Sidakpal S Panaich

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Two Are Better Than One: Are Concomitant Procedures the Future of Transcatheter Interventions?, Sameer Gafoor and Sidakpal S Panaich

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High-throughput single-cell transcriptomics of bacteria using combinatorial barcoding., Karl D Gaisser, Sophie N Skloss, Leandra M Brettner, Luana Paleologu, Charles M Roco, Alexander B Rosenberg, Matthew Hirano, R William DePaolo, Georg Seelig, and Anna Kuchina

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Continuous Glucose Monitoring Metrics and Hemoglobin A1c Relationship in Patients with Type 2 Diabetes Treated by Hemodialysis., Rodolfo J Galindo, Bobak Moazzami, Katherine R Tuttle, Richard M Bergenstal, Limin Peng, and Guillermo E Umpierrez

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A Celebration of Innovation and Discovery in Healthcare, Cara Gallegos

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SOFIA Aspiration System as first-line Technique (SOFAST): a prospective, multicenter study to assess the efficacy and safety of the 6 French SOFIA Flow Plus aspiration catheter for endovascular stroke thrombectomy., Dheeraj Gandhi, Huanwen Chen, Syed Zaidi, Daniel H Sahlein, Lucian Maidan, Kenneth Kreitel, Timothy R Miller, Scott Rahimi, Amer Al Shekhlee, Henry H Woo, Gabor Toth, Clemens Schirmer, Yince Loh, and David Fiorella

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Pretest-post-test evaluation with lay midwives in remote Guatemala after educational activities about COVID-19., Kimberly S Garcia, Argelia Rodriguez, Zoila Gonzalez, Cheryl Armstrong, Eli Iacob, Emily E Flynn, and Molly Simmons

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A randomized phase III study of standard versus high-dose cytarabine with or without vorinostat for AML., Guillermo Garcia-Manero, Nikolai A Podoltsev, Megan Othus, John M Pagel, Jerald P Radich, Min Fang, David A Rizzieri, Guido Marcucci, Stephen A Strickland, Mark R Litzow, M Lynn Savoie, Bruno C Medeiros, Mikkael A Sekeres, Tara L Lin, Geoffrey L Uy, Bayard L Powell, Jonathan E Kolitz, Richard A Larson, Richard M Stone, David Claxton, James Essell, Selina M Luger, Sanjay R Mohan, Anna Moseley, Frederick R Appelbaum, and Harry P Erba

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The hidden risk: Intracranial hemorrhage following durotomies in spine surgery., Julius Gerstmeyer, August Avantaggio, Clifford A Pierre, Neel Patel, Donald D Davis, Bryan Anderson, Periklis Godolias, Thomas Schildhauer, Amir Abdul-Jabbar, Rod J Oskouian, and Jens R Chapman

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Re: Propensity-matched Analysis of Open Versus Robotic Primary Retroperitoneal Lymph Node Dissection for Clinical Stage II Testicular Cancer., Alireza Ghoreifi, James R Porter, and Hooman Djaladat

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Skin Biopsy Detection of Phosphorylated α-Synuclein in Patients With Synucleinopathies., Christopher H Gibbons, Todd Levine, Charles Adler, Bailey Bellaire, Ningshan Wang, Jade Stohl, Pinky Agarwal, Georgina M Aldridge, Alexandru Barboi, Virgilio G H Evidente, Douglas Galasko, Michael D Geschwind, Alejandra Gonzalez-Duarte, Ramon Gil, Mark Gudesblatt, Stuart H Isaacson, Horacio Kaufmann, Pravin Khemani, Rajeev Kumar, Guillaume Lamotte, Andy J Liu, Nikolaus R McFarland, Mitchell Miglis, Adam Reynolds, Gregory A Sahagian, Marie-Helene Saint-Hillaire, Julie B Schwartzbard, Wolfgang Singer, Michael J Soileau, Steven Vernino, Oleg Yerstein, and Roy Freeman

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The effect of pleural drainage on pulse oximetry in a post-operative thoracic surgery population., Christopher R Gilbert, Jason A Akulian, Candice L Wilshire, Samira Shojaee, Adam J Bograd, and Jed A Gorden

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The Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) Celebrates Its 20th Anniversary., Dafna D Gladman, Philip S Helliwell, and Philip J Mease

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Evaluating student performance assessment methods in Objective Structured Clinical Exam: perspectives and comparisons., Matthew Godwin, Amy J Lin, Rahaf Bin Hamdan, Muath Aldosari, Luis Lopez, and Sang E Park

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Phase 1 trial of TPI 287, a microtubule stabilizing agent, in combination with bevacizumab in adults with recurrent glioblastoma., Samuel A Goldlust, Louis B Nabors, Sigmund Hsu, Nimish Mohile, Paul J Duic, Tara Benkers, Samuel Singer, Mayank Rao, Lori Cappello, Sandra L Silberman, and George Farmer

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How Should Health Care Organizations Limit Roles of Human Trafficking in Their Labor and Supply Chains?, Mollie Gordon, Rebecca Chen, John Coverdale, Mike Schiller, Hanni Stoklosa, and Phuong Nguyen

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EULAR recommendations for the management of psoriatic arthritis with pharmacological therapies: 2023 update., Laure Gossec, Andreas Kerschbaumer, Ricardo J O Ferreira, Daniel Aletaha, Xenofon Baraliakos, Heidi Bertheussen, Wolf-Henning Boehncke, Bente Appel Esbensen, Iain B McInnes, Dennis McGonagle, Kevin L Winthrop, Andra Balanescu, Peter V Balint, Gerd R Burmester, Juan D Cañete, Pascal Claudepierre, Lihi Eder, Merete Lund Hetland, Annamaria Iagnocco, Lars Erik Kristensen, Rik Lories, Rubén Queiro, Daniele Mauro, Helena Marzo-Ortega, Philip Mease, Peter Nash, Wendy Wagenaar, Laura Savage, Georg Schett, Stephanie J W Shoop-Worrall, Yoshiya Tanaka, Filip E Van den Bosch, Annette van der Helm-van Mil, Alen Zabotti, Désirée van der Heijde, and Josef S Smolen

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Learning Circles: Promoting Inclusive Care Starting in the Classroom, April Graham, Kindsey Gattman, and Tobias Johnson

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Increasing Realism and Variety of Virtual Patient Dialogues for Prenatal Counseling Education Through a Novel Application of ChatGPT: Exploratory Observational Study., Megan Gray, Austin Baird, Taylor Sawyer, Jasmine James, Thea DeBroux, Michelle Bartlett, Jeanne Krick, and Rachel Umoren

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Treating chronic wounds in an acute care setting: the forgotten diagnosis., Emily Sue Greenstein, William Falone, Teresa Patterson, Katherine Cesario, Linda Mitchell, Tanya Martel, Julie Rivera, Maarten Vooijs, and Sarah Norton

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TIME-seq reduces time and cost of DNA methylation measurement for epigenetic clock construction., Patrick T Griffin, Alice E Kane, Alexandre Trapp, Jien Li, Matthew Arnold, Jesse R Poganik, Ryan J Conway, Maeve S McNamara, Margarita V Meer, Noah Hoffman, João A Amorim, Xiao Tian, Michael R MacArthur, Sarah J Mitchell, Amber L Mueller, Colleen Carmody, Daniel L Vera, Csaba Kerepesi, Kejun Ying, Nicole Noren Hooten, James R Mitchell, Michele K Evans, Vadim N Gladyshev, and David A Sinclair

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A data-driven approach to improve wellness and reduce recurrence in cancer survivors., Ramkumar Hariharan, Leroy Hood, and Nathan D Price

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Near-infrared technology for improved PIVC placement: a clinical technology implementation model., Charlotte Hart and Elizabeth Weathers

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Optimize and Thrive: An Electronic Health Record Optimization Program Case Study., Sarah Hathaway and Melinda Earle

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Outcomes of a same day discharge protocol in patients undergoing mastectomy and implant reconstruction., Danielle Hayes, Wandra K Miles, Monica Solorio, and Suzette G Miranda

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Occupational nerve injuries., Sandra L Hearn, Shawn P Jorgensen, Joelle M Gabet, and Gregory T Carter

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Design and baseline characteristics of the Finerenone, in addition to standard of care, on the progression of kidney disease in patients with Non-Diabetic Chronic Kidney Disease (FIND-CKD) randomized trial., Hiddo J L Heerspink, Rajiv Agarwal, George L Bakris, David Z I Cherney, Carolyn S P Lam, Brendon L Neuen, Pantelis A Sarafidis, Katherine Tuttle, Christoph Wanner, Meike D Brinker, Sara Dizayee, Peter Kolkhof, Patrick Schloemer, Paula Vesterinen, and Vlado Perkovic

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Selonsertib in Patients with Diabetic Kidney Disease: A Phase 2b Randomized Active Run-In Clinical Trial., Hiddo J L Heerspink, Vlado Perkovic, Katherine R Tuttle, Pablo E Pergola, Kenneth W Mahaffey, Uptal D Patel, Julie H Ishida, Albert Kuo, Fang Chen, Robert Kustra, Vladimir Petrovic, Peter Rossing, Naoki Kashihara, and Glenn M Chertow

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Visual explanations for polyp detection: How medical doctors assess intrinsic versus extrinsic explanations., Steven Hicks, Andrea Storås, Michael A Riegler, Cise Midoglu, Malek Hammou, Thomas de Lange, Sravanthi Parasa, Pål Halvorsen, and Inga Strümke

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Upfront or delayed surgery in resectable hepatoblastoma: analysis from the children's hepatic tumors international collaboration database., Eiso Hiyama, Tomoro Hishiki, Kenichi Yoshimura, Mark Krailo, Rudolf Maibach, Beate Haeberle, Arun Rangaswami, Dolores Lopez-Terrada, Marcio H Malogolowkin, Marc Ansari, Rita Alaggio, Allison F O'Neill, Angela D Trobaugh-Lotrario, Kenichiro Watanabe, Irene Schmid, Sarangarajan Ranganathan, Yukichi Tanaka, Takeshi Inoue, Jin Piao, Jason Lin, Piotr Czauderna, Rebecka L Meyers, and Daniel C Aronson

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Emergency department responses to nursing shortages., Nicole R Hodgson, Richard Kwun, Chad Gorbatkin, Jeanie Davies, Jonathan Fisher, and ACEP Emergency Medicine Practice Committee

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Mechanical Thrombectomy for High-Risk Pulmonary Embolism: Insights From the US Cohort of the FLASH Registry., James M Horowitz, Wissam A Jaber, Brian Stegman, Michael Rosenberg, Christina Fanola, Ambarish P Bhat, Sreedevi Gondi, Jordan Castle, Mustafa Ahmed, Michael A Brown, Rohit Amin, Mohannad Bisharat, Paul Butros, Aaron DuCoffe, Michael Savin, Jeffrey S Pollak, Mitchell D Weinberg, Daniel Brancheau, and Catalin Toma

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A Multisite Initiative to Increase Utilization of Clinical Pathways in the Selection of Systemic Cancer Treatment, Kate Hough

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A Modified Delphi Study for Curricular Content of Simulation-Based Medical Education for Pediatric Residency Programs., Lorel Huber, Ryan Good, Meredith F Bone, Shannon M Flood, Ryan Fredericks, Frank Overly, Nancy M Tofil, Robyn Wing, and Kathryn Walsh

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Peri-clitoral epidermal inclusion cyst as initial presentation of lichen sclerosus in a pediatric patient., Emily Huebner, Kate Debiec, Angela Hernandez, and Lissa Yu

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Contribution of Microorganisms with the Clade II Nitrous Oxide Reductase to Suppression of Surface Emissions of Nitrous Oxide., Kristopher A Hunt, Alex V Carr, Anne E Otwell, Jacob J Valenzuela, Kathleen S Walker, Emma R Dixon, Lauren M Lui, Torben N Nielsen, Samuel Bowman, Frederick von Netzer, Ji-Won Moon, Christopher W Schadt, Miguel Rodriguez, Kenneth Lowe, Dominique Joyner, Katherine J Davis, Xiaoqin Wu, Romy Chakraborty, Matthew W Fields, Jizhong Zhou, Terry C Hazen, Adam P Arkin, Scott D Wankel, Nitin S Baliga, and David A Stahl

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Bimekizumab provided rapid improvements in patient-reported symptoms and health-related quality of life in patients with active psoriatic arthritis: pooled 16-week results from two phase 3 studies., M Elaine Husni, Philip Mease, Joseph F Merola, William Tillett, Nadine Goldammer, Barbara Ink, Jason Coarse, Jérémy Lambert, Vanessa Taieb, and Dafna D Gladman

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Protocol for the development of a core outcome set for clinical trials in primary sclerosing cholangitis., Nasir Hussain, Christopher Ma, Gideon Hirschfield, Martine Walmsley, Paula Hanford, Mette Vesterhus, Kris V Kowdley, Annika Bergquist, Cyriel Ponsioen, Cynthia Levy, David Assis, Christoph Schramm, Christopher Bowlus, Michael Trauner, Olalekan Lee Aiyegbusi, Vipul Jairath, and Palak J Trivedi

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Timing of selective serotonin reuptake inhibitor use and risk for preterm birth and related adverse events: with a consideration of the COVID-19 pandemic period., Yeon Mi Hwang, Ryan T Roper, Samantha N Piekos, Daniel A Enquobahrie, Mary F Hebert, Alison G Paquette, Priyanka Baloni, Nathan D Price, Leroy Hood, and Jennifer J Hadlock

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Maternal-fetal outcomes in patients with immune-mediated inflammatory diseases, with consideration of comorbidities: a retrospective cohort study in a large U.S. healthcare system., Yeon Mi Hwang, Qi Wei, Samantha N Piekos, Bhargav Vemuri, Sevda Molani, Philip Mease, Leroy Hood, and Jennifer Hadlock

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Thirty- and 90-Day Morbidity and Mortality by Clavien-Dindo 30 and 90 Days after Surgery for Antireflux and Hiatal Hernia., Megan L Ivy, George Baison, Cassandra Griffin, Allison C Welch, Peter T White, Alexander S Farivar, Adam J Bograd, Ralph W Aye, and Brian E Louie

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Morbidity and mortality after antireflux and hiatal hernia surgery across a spectrum of ages., Megan L Ivy, Alexander S Farivar, George N Baison, Cassandra Griffin, Adam J Bograd, Peter T White, and Brian E Louie

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The Burden of Work Productivity and Activity Impairment in Patients with Psoriasis, Psoriatic Arthritis, Ulcerative Colitis, and Crohn's Disease., Jud C Janak, Anita M Loughlin, Page C Moore, Celeste A Lemay, Philip J Mease, Mark Lebwohl, Joshua R Korzenik, Raymond K Cross, and David Hudesman

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Characterization of peer support services for substance use disorders in 11 US emergency departments in 2020: findings from a NIDA clinical trials network site selection process., Lindsey K Jennings, Laura Lander, Tricia Lawdahl, Erin A McClure, Angela Moreland, Jenna L McCauley, Louise Haynes, Timothy Matheson, Richard Jones, Thomas E Robey, Sarah Kawasaki, Phillip Moschella, Amer Raheemullah, Suzette Miller, Gina Gregovich, Deborah Waltman, Kathleen T Brady, and Kelly S Barth

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Validating polyp and instrument segmentation methods in colonoscopy through Medico 2020 and MedAI 2021 Challenges., Debesh Jha, Vanshali Sharma, Debapriya Banik, Debayan Bhattacharya, Kaushiki Roy, Steven A Hicks, Nikhil Kumar Tomar, Vajira Thambawita, Adrian Krenzer, Ge-Peng Ji, Sahadev Poudel, George Batchkala, Saruar Alam, Awadelrahman M A Ahmed, Quoc-Huy Trinh, Zeshan Khan, Tien-Phat Nguyen, Shruti Shrestha, Sabari Nathan, Jeonghwan Gwak, Ritika K Jha, Zheyuan Zhang, Alexander Schlaefer, Debotosh Bhattacharjee, M K Bhuyan, Pradip K Das, Deng-Ping Fan, Sravanthi Parasa, Sharib Ali, Michael A Riegler, Pål Halvorsen, Thomas de Lange, and Ulas Bagci

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Comprehensive Overview of Bottom-Up Proteomics Using Mass Spectrometry., Yuming Jiang, Devasahayam Arokia Balaya Rex, Dina Schuster, Benjamin A Neely, Germán L Rosano, Norbert Volkmar, Amanda Momenzadeh, Trenton M Peters-Clarke, Susan B Egbert, Simion Kreimer, Emma H Doud, Oliver M Crook, Amit Kumar Yadav, Muralidharan Vanuopadath, Adrian D Hegeman, Martín L Mayta, Anna G Duboff, Nicholas M Riley, Robert L Moritz, and Jesse G Meyer

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A Longitudinal Assessment of Resident and New Graduate Well-Being According to Length of Training: A Report From the Length of Training Pilot in Family Medicine., Mark Johnson, Patricia A Carney, Annie Ericson, Briana Money, Suki Tepperberg, Nicholas Weida, Jennifer Somers, and Jennifer Romeu

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Aberrant bowel movement frequencies coincide with increased microbe-derived blood metabolites associated with reduced organ function., Johannes P Johnson-Martínez, Christian Diener, Anne E Levine, Tomasz Wilmanski, David L Suskind, Alexandra Ralevski, Jennifer Hadlock, Andrew T Magis, Leroy Hood, Noa Rappaport, and Sean M Gibbons

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Healthcare Professional Awareness of Climate Health and an Evidence-based Environmental Stewardship Framework, Patricia Joubert, Rosemary Timmerman, Angie Shemwell, Barbara Ngyuen, and Teresa Rangel

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Tertiary Care Center Trends in Colonic Stent Placement over the Past Decade., Wassem Y Juakiem, Kelita Singh, Andrew Ofosu, Daryl Ramai, Alana Persaud, James H Tabibian, Eduardo Rodrigues-Pinto, Mohit Girotra, and Monique T Barakat

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Multimodal Spatial Profiling Reveals Immune Suppression and Microenvironment Remodeling in Fallopian Tube Precursors to High-Grade Serous Ovarian Carcinoma., Tanjina Kader, Jia-Ren Lin, Clemens Hug, Shannon Coy, Yu-An Chen, Ino de Bruijn, Natalie Shih, Euihye Jung, Roxanne J Pelletier, Mariana Lopez Leon, Gabriel Mingo, Dalia Khaled Omran, Jong Suk Lee, Clarence Yapp, Baby Anusha Satravada, Ritika Kundra, Yilin Xu, Sabrina Chan, Juliann B Tefft, Jeremy Muhlich, Sarah Kim, Stefan M Gysler, Judith Agudo, James R Heath, Nikolaus Schultz, Charles Drescher, Peter K Sorger, Ronny Drapkin, and Sandro Santagata

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People with multiple sclerosis help design a tool to measure physical functioning and how it affects their daily lives: a plain language summary., Paul Kamudoni, Dagmar Amtmann, Jeffrey Johns, Karon F Cook, Rana Salem, Sam Salek, Jana Raab, Rod Middleton, P Repovic, Kevin N Alschuler, Gloria von Geldern, Annette Wundes, Amy Barrett, Oyebimpe Olayinka-Amao, and Christian Henke

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Multi-omic profiling of simultaneous ductal carcinoma in situ and invasive breast cancer., Henry G Kaplan, Alexa K Dowdell, Anna B Berry, Racheli Ben Shimol, Fred L Robinson, Christopher A Carney, and Brian D. Piening

Alcohol Treatment Utilization Patterns: Analysis of Variation by Race and Ethnicity, KJ Karriker-Jaffe, J Delk, J Cance, N Mulia, G Bobashev, Kara M. Bensley, S Zenmore, C Barbosa, and T Mark

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Inflammation, endothelial injury, and the acute respiratory distress syndrome after out-of-hospital cardiac arrest., Sarah C Katsandres, Jane Hall, Kyle Danielson, Sana Sakr, Sarah G Dean, David J Carlbom, Mark M Wurfel, Pavan K Bhatraju, Joseph A Hippensteel, Eric P Schmidt, Kaori Oshima, Catherine R Counts, Michael R Sayre, Daniel J Henning, and Nicholas J Johnson

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Cosmos MIND and matter: Is mind in spacetime?, Stuart Kauffman and Sudip Patra

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Cosmos, mind, matter: Is mind in spacetime?, Stuart Kauffman and Sudip Patra

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Deucravacitinib, a selective, TYK2 inhibitor, in psoriatic arthritis: Achievement of minimal disease activity components in a phase 2 trial., Arthur Kavanaugh, Laura C Coates, Philip Mease, Miroslawa Nowak, Lauren Hippeli, Thomas Lehman, Subhashis Banerjee, and Joseph F Merola

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Association Between Achievement of Clinical Disease Control and Improvement in Patient-Reported Outcomes and Quality of Life in Patients With Psoriatic Arthritis in the Phase 3 SELECT-PsA 1 and 2 Randomized Controlled Trials., Arthur Kavanaugh, Philip Mease, Laure Gossec, Roberto Ranza, Shigeyoshi Tsuji, Kevin Douglas, Michael Lane, Ralph Lippe, Manish Mittal, Tianming Gao, Arathi Setty, Sandra Ciecinski, Daniel Aletaha, and Peter Nash

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Patient with macrocomplexes for both creatine kinase and cardiac troponin reveals the importance of immunoassay methods for macrotroponin detection., Peter A Kavsak, Basma Ahmed, David Ivanick, Dina N Greene, and Pratistha Ranjitkar

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Lactate Oxidase Disrupts Lactate-Activated RAS and PI3K Oncogenic Signaling., Chandler R Keller, Steve R Martinez, Alexys Keltz, Michelle Chen, and Weimin Li

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“Care for Me” Companion Cart, Helen Kelly, Kristofferson Yu, John Delfeld, and Tom Thomas

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Health Professional Concern for Environment and Behaviors to Protect Climate Health, Mary Jo Kelly, Sarah Johnson, Teresa Rangel, and Gale Springer

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Osteoporotic Fractures: Diagnosis, Evaluation, and Significance From the International Working Group on DXA Best Practices., Aliya A Khan, Riemer H J A Slart, Dalal S Ali, Oliver Bock, John J Carey, Pauline Camacho, Klaus Engelke, Paola A Erba, Nicholas C Harvey, Willem F Lems, Sarah Morgan, Kendall F Moseley, Christopher O'Brien, Linda Probyn, Marija Punda, Bradford Richmond, John T Schousboe, Christopher Shuhart, Kate A Ward, and E Michael Lewiecki

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Development and Validation of the American Heart Association's PREVENT Equations., Sadiya S Khan, Kunihiro Matsushita, Yingying Sang, Shoshana H Ballew, Morgan E Grams, Aditya Surapaneni, Michael J Blaha, April P Carson, Alexander R Chang, Elizabeth Ciemins, Alan S Go, Orlando M Gutierrez, Shih-Jen Hwang, Simerjot K Jassal, Csaba P Kovesdy, Donald M Lloyd-Jones, Michael G Shlipak, Latha P Palaniappan, Laurence Sperling, Salim S Virani, Katherine Tuttle, Ian J Neeland, Sheryl L Chow, Janani Rangaswami, Michael J Pencina, Chiadi E Ndumele, Josef Coresh, and Chronic Kidney Disease Prognosis Consortium and the American Heart Association Cardiovascular-Kidney-Metabolic Science Advisory Group

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Management of Complications After Per Oral Endoscopic Myotomy., Francois Khazoom and Brian Louie

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A narrative review of how infection preventionist (IP) staffing and outcome metrics are assessed by health care organizations and factors to consider., Shanina C Knighton, Joshua Engle, Julia Berkson, and Rebecca Bartles

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Selecting informative patients for phase 2 progressive trials in MS: Design considerations for phase 2 clinical trials in progressive MS., Marcus W Koch, Carlos Camara-Lemarroy, Eva Strijbis, Jop Mostert, Victoria M Leavitt, P Repovic, J D Bowen, Jacynthe Comtois, Bernard Uitdehaag, and Gary Cutter

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Response., Divyanshoo R Kohli and Mohammad Shadab Siddiqui