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Publication Date
2024
Keywords
oregon, psvmc, oregom gme
Disciplines
Health Information Technology | Hematology | Medical Education | Medical Immunology | Oncology
Abstract
Abstract: Cancer associated venous thromboembolisms (VTE) are associated with higher health care resource utilization (number of hospitalizations, hospital length of stay, inpatient/outpatient medical services) and can complicate treatment of cancer. The Khorana Predictive Model for Chemotherapy-Associated VTE is a validated risk assessment model that determines a patient’s risk of developing VTEs and provides recommendations for starting prophylactic anticoagulation in ambulatory oncology patients. The Khorana Score is composed of various patient characteristics including site of primary cancer, prechemotherapy platelet count, hemoglobin level, prechemotherapy leukocyte count, and BMI. National Comprehensive Cancer Network (NCCN) supportive care guidelines recommend prophylactically starting an anticoagulant if a patient has a Khorana score ≥2. Currently at the Providence Cancer Institute, there is no process in place that utilizes the Khorana Predictive Model in our ambulatory oncology patients. The purpose of this clinical inquiry is to assess the current practice of VTE prophylaxis and identify the need for a system wide implementation of the Khorana Predictive Model. This is a single institution retrospective chart review of patients 18 years or older who were on chemotherapy at Providence Cancer Institute outpatient facilities from September 2022 through September 2023. Patients participating in clinical trials were excluded from this study due to clinical trials may have specific management requirements, adverse event reporting, or rules surrounding addition of other medications. Patients Reports were generated via Slicer Dicer in EPIC to identify patients with specific cancer diagnosis and BMI. Patient charts were reviewed to assess the pretreatment hematologic parameters needed to calculate Khorana scores. Rates of VTEs and compliance with NCCN VTE prophylaxis guideline recommendations were evaluated in multiple subgroups using descriptive statistical analyses. Results and Conclusions will be shared when the project is completed. (IRB exempt) Learning Objectives: Discuss the literature surrounding the Khorana Predictive Model. Describe the implications of utilizing a VTE risk assessment model in ambulatory oncology patients. Presentation Category: Anticoagulation; Hematology/oncology/ immunology/transplant; Ambulatory care/ disease state management
Specialty/Research Institute
Graduate Medical Education
Specialty/Research Institute
Hematology
Specialty/Research Institute
Health Information Technology
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Health Information Technology Commons, Hematology Commons, Medical Education Commons, Medical Immunology Commons, Oncology Commons
