Our expanded team of specialists – many of whom completed fellowships and residencies at prestigious academic centers – offers comprehensive services for treating any condition of the brain, spine and nervous system. With nearly 50 subspecialties represented, we offer complex and minimally invasive surgery as well as ongoing care for pituitary and skull base tumors, stroke, peripheral nerve disease, multiple sclerosis, Parkinson’s disease, Alzheimer’s disease, ALS, epilepsy and more.

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Submissions from 2017

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The ancient Syrian physician Archigenes and his contributions to neurology and neuroanatomy., Michael James Montalbano, Amit Sharma, Rod J Oskouian, Marios Loukas, and R Shane Tubbs

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Systematic Evaluation of Patients Treated With Neurothrombectomy Devices for Acute Ischemic Stroke: Primary Results of the STRATIS Registry., Nils H Mueller-Kronast, Osama O Zaidat, Michael T Froehler, Reza Jahan, Mohammad Ali Aziz-Sultan, Richard P Klucznik, Jeffrey L Saver, Frank R Hellinger, Dileep R Yavagal, Tom L Yao, David S Liebeskind, Ashutosh P Jadhav, Rishi Gupta, Ameer E Hassan, Coleman O Martin, Hormozd Bozorgchami, Ritesh Kaushal, Raul G Nogueira, Ravi H Gandhi, Eric C Peterson, Shervin R Dashti, Curtis A Given, Brijesh P Mehta, Vivek Deshmukh, Sidney Starkman, Italo Linfante, Scott H McPherson, Peter Kvamme, Thomas J Grobelny, Muhammad S Hussain, Ike Thacker, Nirav Vora, Peng Roc Chen, Stephen J Monteith, Robert D Ecker, Clemens M Schirmer, Eric Sauvageau, Alex Abou-Chebl, Colin P Derdeyn, Lucian Maidan, Aamir Badruddin, Adnan H Siddiqui, Travis M Dumont, Abdulnasser Alhajeri, M Asif Taqi, Khaled Asi, Jeffrey Carpenter, Alan Boulos, Gaurav Jindal, Ajit S Puri, Rohan Chitale, Eric M Deshaies, David H Robinson, David F Kallmes, Blaise W Baxter, Mouhammad A Jumaa, Peter Sunenshine, Aniel Majjhoo, Joey D English, Shuichi Suzuki, Richard D Fessler, Josser E Delgado Almandoz, Jerry C Martin, and Diogo C Haussen

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Long-term Outcomes After Autologous Hematopoietic Stem Cell Transplantation for Multiple Sclerosis., Paolo A Muraro, Marcelo Pasquini, Harold L Atkins, James D Bowen, Dominique Farge, Athanasios Fassas, Mark S Freedman, George E Georges, Francesca Gualandi, Nelson Hamerschlak, Eva Havrdova, Vassilios K Kimiskidis, Tomas Kozak, Giovanni L Mancardi, Luca Massacesi, Daniela A Moraes, Richard A Nash, Steven Pavletic, Jian Ouyang, Montserrat Rovira, Albert Saiz, Belinda Simoes, Marek Trnený, Lin Zhu, Manuela Badoglio, Xiaobo Zhong, Maria Pia Sormani, and Riccardo Saccardi

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Management of Hangman's Fractures: A Systematic Review., Hamadi Murphy, Gregory D Schroeder, Weilong J Shi, Christopher K Kepler, Mark F Kurd, Andrew N Fleischman, Frank Kandziora, Jens R Chapman, Lorin M Benneker, and Alexander R Vaccaro

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Feasibility and Data Quality of the National Spinal Cord Injury Registry of Iran (NSCIR-IR): A Pilot Study., Khatereh Naghdi, Zahra Azadmanjir, Soheil Saadat, Aidin Abedi, Sahar Koohi Habibi, Pegah Derakhshan, Mahdi Safdarian, Shayan Abdollah Zadegan, Abbas Amirjamshidi, Mahdi Sharif-Alhoseini, Jalil Arab Kheradmand, Mahdi Mohammadzadeh, Kazem Zendehdel, Zahra Khazaeipour, Seyed Mahmood Ramak Hashemi, Hooshang Saberi, Kourosh Karimi Yarandi, Seyed Ebrahim Ketabchi, Shahrokh Yousefzadeh-Chabok, Hamid Heidari, Arezo Sotodeh, Khalil Pestei, Zahra Ghodsi, Farideh Sadeghian, Vanessa Noonan, Edward C Benzel, Gerard Oreilly, Jens Chapman, Ellen Merete Hagen, Michael G Fehlings, Alexander R Vaccaro, Morteza Faghih Jooybari, Mohammad Reza Zarei, Mohammad Reza Zafarghandi, Payman Salamati, Saeed Nezareh, Moein Khormali, Mohsen Sadeghi-Naini, Seyed Behzad Jazayeri, Bizhan Aarabi, and Vafa Rahimi-Movaghar

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The semiology of benign focal epilepsy with affective symptoms., Fábio A Nascimento, Márcio A Sotero de Menezes, Cristiane A Simão, Bruno T Takeshita, Samanta F Blattes da Rocha, and Pedro A Kowacs

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High-dose immunosuppressive therapy and autologous HCT for relapsing-remitting MS., Richard A Nash, George J Hutton, Michael K Racke, Uday Popat, Steven M Devine, Kaitlyn C Steinmiller, Linda M Griffith, Paolo A Muraro, Harry Openshaw, Peter H Sayre, Olaf Stuve, Douglas L Arnold, Mark H Wener, George E Georges, Annette Wundes, George H Kraft, and J D Bowen

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Toxoplasma Modulates Signature Pathways of Human Epilepsy, Neurodegeneration & Cancer., Huân M Ngô, Ying Zhou, Hernan Lorenzi, Kai Wang, Taek-Kyun Kim, Yong Zhou, Kamal El Bissati, Ernest Mui, Laura Fraczek, Seesandra V Rajagopala, Craig W Roberts, Fiona L Henriquez, Alexandre Montpetit, Jenefer M Blackwell, Sarra E Jamieson, Kelsey Wheeler, Ian J Begeman, Carlos Naranjo-Galvis, Ney Alliey-Rodriguez, Roderick G Davis, Liliana Soroceanu, Charles Cobbs, Dennis A Steindler, Kenneth Boyer, A Gwendolyn Noble, Charles N Swisher, Peter T Heydemann, Peter Rabiah, Shawn Withers, Patricia Soteropoulos, Leroy Hood, and Rima McLeod

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Comparing Quality of Life in Cervical Spondylotic Myelopathy with Other Chronic Debilitating Diseases Using the Short Form Survey 36-Health Survey., Taemin Oh, Renaud Lafage, Virginie Lafage, Themistocles Protopsaltis, Vincent Challier, Christopher Shaffrey, Han Jo Kim, Paul Arnold, Jens R Chapman, Frank Schwab, Eric Massicotte, Tim Yoon, Shay Bess, Michael Fehlings, Justin Smith, and Christopher Ames

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Spine Trauma-What Are the Current Controversies?, Cumhur Oner, Shanmuganathan Rajasekaran, Jens R Chapman, Michael G Fehlings, Alexander R Vaccaro, Gregory D Schroeder, Said Sadiqi, and James Harrop

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Enhanced retinal responses in Huntington's disease patients., Jocelynn R Pearl, Laura M Heath, Dani E Bergey, John P Kelly, Corrie Smith, Mercy Y Laurino, Avery Weiss, Nathan D Price, Albert LaSpada, Thomas D Bird, and Suman Jayadev

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Despite worse baseline status depressed patients achieved outcomes similar to those in nondepressed patients after surgery for cervical deformity., Gregory W Poorman, Peter G Passias, Samantha R Horn, Nicholas J Frangella, Alan H Daniels, D Kojo Hamilton, Hanjo Kim, Daniel Sciubba, Bassel G Diebo, Cole A Bortz, Frank A Segreto, Michael P Kelly, Justin S Smith, Brian J Neuman, Christopher I Shaffrey, Virginie LaFage, Renaud LaFage, Christopher P Ames, Robert A Hart, Gregory M Mundis, and Robert Eastlack

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Update on the Notochord Including its Embryology, Molecular Development, and Pathology: A Primer for the Clinician., Tushar Ramesh, Sai V Nagula, Gabrielle G Tardieu, Erfanul Saker, Mohammadali Shoja, Marios Loukas, Rod J Oskouian, and R Shane Tubbs

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Proximal Junctional Kyphosis: Inter- and Intra-observer Reliability of Radiographic Measurements in Adult Spinal Deformity., Farbod Rastegar, Alec Contag, Alan Daniels, Jayme Hiratzka, Clifford Lin, Jason Chang, Khoi Than, Ahmed Raslan, Christopher Kong, Ngoc-Lam Nguyen, Richard Hostin, Marie Kane, and Robert A Hart

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Brief Cognitive Screening Tools for Primary Care Practice, K Rhoads, Nancy B. Isenberg, and L Korte

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Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimer's disease resilience., Perry G Ridge, Celeste M Karch, Simon Hsu, Ivan Arano, Craig C Teerlink, Mark T W Ebbert, Josue D Gonzalez Murcia, James M Farnham, Anna R Damato, Mariet Allen, Xue Wang, Oscar Harari, Victoria M Fernandez, Rita Guerreiro, Jose Bras, John Hardy, Ronald Munger, Maria Norton, Celeste Sassi, Andrew Singleton, Steven G Younkin, Dennis W Dickson, Todd E Golde, Nathan D Price, Nilüfer Ertekin-Taner, Carlos Cruchaga, Alison M Goate, Christopher Corcoran, JoAnn Tschanz, Lisa A Cannon-Albright, and John S K Kauwe

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Research conference summary from the 2014 International Task Force on, Hendrik Rosewich, Matthew T Sweney, Suzanne DeBrosse, Kevin Ess, Laurie Ozelius, Eva Andermann, Frederick Andermann, Gene Andrasco, Alice Belgrade, Allison Brashear, Sharon Ciccodicola, Lynn Egan, Alfred L George, Aga Lewelt, Joshua Magelby, Mario Merida, Tara Newcomb, Vicky Platt, Dominic Poncelin, Sandra Reyna, Masayuki Sasaki, Márcio A Sotero de Menezes, Kathleen Sweadner, Louis Viollet, Mary Zupanc, Kenneth Silver, and Kathryn Swoboda

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Fractures in Spinal Ankylosing Disorders: A Narrative Review of Disease and Injury Types, Treatment Techniques, and Outcomes., Tarush Rustagi, Doniel Drazin, Cumhur Oner, Jonathan York, Gregory D Schroeder, Alexander R Vaccaro, Rod J Oskouian, and Jens R Chapman

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Anatomic Variations of the Anterior Atlantodental Joint and Relations to the Apical and Alar Ligaments in a Geriatric Population., Tarush Rustagi, Joe Iwanaga, Juan P Sardi, Fernando Alonso, Rod J Oskouian, and R Shane Tubbs

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Anatomy of the Alar Ligament: Part II: Variations of Its Attachment onto the Dens., Juan P Sardi, Joe Iwanaga, Cameron Schmidt, Tarush Rustagi, Jens R Chapman, Rod J Oskouian, and R Shane Tubbs

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Cognitive dysfunction in patients with brain metastases: influences on caregiver resilience and coping., Marlon Garzo Saria, Natasia Courchesne, Lorraine Evangelista, Joshua Carter, Daniel A MacManus, Mary Kay Gorman, Adeline M Nyamathi, Linda R Phillips, David Piccioni, Santosh Kesari, and Sally Maliski

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"Wave" of the Future in Neuroanesthesiology Too!, Brian E Schmidt and Arthur M Lam

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Meningocele manqué: a comprehensive review of this enigmatic finding in occult spinal dysraphism., Cameron Schmidt, Ellie Bryant, Joe Iwanaga, Rod J Oskouian, W Jerry Oakes, and R Shane Tubbs

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Absence of the Lumbosacral Trunk., Cameron K Schmidt, Joe Iwanaga, Emre Yilmaz, Charlotte Wilson, Rod J Oskouian, and R Shane Tubbs

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Nerve root anomalies: making sense of a complicated literature., Cameron K Schmidt, Tarush Rustagi, Fernando Alonso, Marios Loukas, Jens R Chapman, Rod J Oskouian, and R Shane Tubbs

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Junctional neural tube defect in a newborn: report of a fourth case., Cameron Schmidt, Vlad Voin, Joe Iwanaga, Fernando Alonso, Rod J Oskouian, Nitsa Topale, R Shane Tubbs, and W Jerry Oakes

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Letter by Shah Regarding Article, "Randomized, Multicenter Trial of ARTSS-2 (Argatroban With Recombinant Tissue Plasminogen Activator for Acute Stroke)"., Nirav H Shah

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The First Histological Analysis of the Tissues Lining the Fossa Navicularis: Insights to its Etiology., Sarvenaz Sheikh, Joe Iwanaga, Steven Rostad, Tarush Rustagi, Rod J Oskouian, and R Shane Tubbs

Clinical Outcomes for a Multicenter First Seizure and New Onset Epilepsy Clinic Poster Presented at the American Epilespy Society, A Steinsiek, A Lesko, B Baraban, L Lucas, and See full citation in comments

Compliance of a new standard in stroke neuro checks in a comprehensive stroke center compared to primary stroke centers for IV alteplase and thrombectomy patients Poster Presented at the International Stroke Conference, Honolulu, Hawaii, N Swearingen, K Cox, A Lesko, L Lucas, D Clark, and See full citation in comments

Evaluation of Intervention at Reducing Alteplase Returns Without Compromising Clinical Care in Acute Ischemic Stroke Poster Presented at the International Stroke Conference, N Swearingen, J Myers, A Lesko, L Lucas, E Barbaran, and See full citation in comments

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Usher Parsons (1788-1868) and His 19th-Century Understanding and Surgical Treatment of Spinal Curvatures., Gabrielle G Tardieu, Nitsa Topale, Erfanul Saker, Marios Loukas, Rod J Oskouian, and R Shane Tubbs

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Extraforaminal compression of the L5 nerve: An anatomical study with application to failed posterior decompressive procedures., R Shane Tubbs, Joe Iwanaga, Islam Aly, Marc D Moisi, David Hanscom, Jens R Chapman, Marios Loukas, and Rod J Oskouian

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Giant Arachnoid Granulation Associated with Anomalous Draining Vein: A Case Report., Randle Umeh, Rod J Oskouian, Marios Loukas, and R Shane Tubbs

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Answer to the Letter to the Editor of A. Piazzolla et al. concerning, "The Surgical Algorithm for the AOSpine, Thoracolumbar Spine Injury Classification System" by A. R. Vaccaro et al.; Eur Spine J (2016); 25(4):1087-1094., Alexander R Vaccaro, Gregory D Schroeder, Christopher K Kepler, F Cumhur Oner, Luiz R Vialle, Frank Kandziora, John D Koerner, Mark F Kurd, Max Reinhold, Klaus J Schnake, Jens R Chapman, Bizhan Aarabi, Michael G Fehlings, and Marcel F Dvorak

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Neurological improvement of perineural and leptomeningeal spread of squamous cell carcinoma treated with intrathecal chemotherapy and systemic EGFR inhibition., Vincent Alexander van Vugt, Marlon Garzo Saria, Andres Javier, Navin Kesari, Tiffany Turpin, and Santosh Kesari

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Piercing of the Lumbocostal Ligament by the Subcostal Nerve: A Previously Unreported Case., Marc Vetter, Joe Iwanaga, Rod J Oskouian, and R Shane Tubbs

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Relationship of the Median and Radial Nerves at the Elbow: Application to Avoiding Injury During Venipuncture or Other Invasive Procedures of the Cubital Fossa., Vlad Voin, Joe Iwanaga, Juan P Sardi, Christian Fisahn, Marios Loukas, Rod J Oskouian, and R Shane Tubbs

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Editorial., Jeffrey C Wang, Jens R Chapman, and Karsten Wiechert

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Editorial., Jeffrey C Wang, Jens R Chapman, and Karsten Wiechert

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More Than Meets the Eye: The Contributions of John Dalrymple (1803-1852)., Joy Mh Wang, Bryan Edwards, Gabrielle G Tardieu, Marios Loukas, Rod J Oskouian, and R Shane Tubbs

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Alzheimer’s Disease and Other Dementias Workgroup: Alzheimer’s Disease and Other Dementias Report and Recommendations, V Weir (ed), K Rhoads (chair), Nancy B. Isenberg, and See all Group Members in Comments

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Do We Really Understand Spine Treatments and Science Around the World?, Karsten Wiechert, Jeffrey C Wang, and Jens R Chapman

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Medical Journals and Social Media: More Alike Than Wanted?, Karsten Wiechert, Jeffrey C Wang, and Jens R Chapman

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Brain pathology of a patient 7years after autologous hematopoietic stem cell transplantation for multiple sclerosis., Annette Wundes, J D Bowen, George H Kraft, Kenneth R Maravilla, Bernadette McLaughlin, Gloria von Geldern, George Georges, Richard A Nash, and Jian-Qiang Lu

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A novel small molecule inhibitor of p32 mitochondrial protein overexpressed in glioma., Venkata Yenugonda, Natsuko Nomura, Valentina Kouznetsova, Igor Tsigelny, Valentina Fogal, Elmar Nurmemmedov, Santosh Kesari, and Ivan Babic

Submissions from 2016

Positive Impact through Use of Telestroke in Two Large Pacific Northwest Networks on Clinical Performance Accepted for Poster Presentation at Telemediclne & Te!ehealth Service Provider Showcase, Phoenix, AR, E Baraban, A Lesko, L Corless, S Fisher, and See full citation in comments

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Stent-assisted coil embolization of aneurysms with small parent vessels: safety and efficacy analysis., Anna Luisa Kühn, Samuel Y Hou, Ajit S Puri, Christine F Silva, Matthew J Gounis, and Ajay K Wakhloo

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Endovascular reconstruction of unruptured intradural vertebral artery dissecting aneurysms with the Pipeline embolization device., Anna Luisa Kühn, Peter Kan, Francesco Massari, J Diego Lozano, Samuel Y Hou, Mary Howk, Matthew J Gounis, Ajay K Wakhloo, and Ajit S Puri

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Safety, efficacy, and short-term follow-up of the use of Pipeline Embolization Device in small (<2.5 mm) cerebral vessels for aneurysm treatment: single institution experience., Ajit S Puri, Francesco Massari, Takumi Asai, Miklos Marosfoi, Peter Kan, Samuel Y Hou, Mary Howk, Mary Perras, Christopher Brooks, Frederic Clarencon, Matthew J Gounis, and Ajay K Wakhloo

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Onyx embolization in distal dissecting posterior inferior cerebellar artery aneurysms., Ajit S Puri, Francesco Massari, Samuel Y Hou, Juan Diego Lozano, Mary Howk, Mary Perras, Christopher Brooks, Matthew J Gounis, Peter Kan, and Ajay K Wakhloo

Submissions from 2015

The Cost-Effectiveness of Telestroke Varies by Implementation Cost and Stroke Severity: Real World Data from a Pacific Northwest Group Poster Presented at the International Stroke Conference, Nashville, TN, E Baraban, L Lucas, and A Lesko

Patients with Low NIHSS Stroke Scales Have Longer Door to Needle Times: An Analysis of a Telestroke Network Poster Presented at the International Stroke Conference, Nashville, TN, E Baraban, R Nelson, A Lesko, J Majersik, and See full citation in comments

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Flow diverter stents for unruptured saccular anterior circulation perforating artery aneurysms: safety, efficacy, and short-term follow-up., Anna Luisa Kühn, Samuel Y Hou, Mary Perras, Christopher Brooks, Matthew J Gounis, Ajay K Wakhloo, and Ajit S Puri

Budget Impact Analysis of Telestroke in the Pacific Northwest Poster Presented at the International Stroke Conference, Nashville, TN, R Nelson, A Lesko, Okon J, Bhatt N, and See full citation in comments

The Cost-Effectiveness of Telestroke in the Pacific Northwest Region of the USA Journal of Telemedicine and Telecare, OnlineFirst, R Nelson, N Okon, A Lesko, J Majersik, and See full citation in comments

Telestroke Network Cost Effectiveness in the Pacific Northwest: Geography and Facility Size Support a Cost-Sharing Model Between Hub and Spoke Poster Presented at the International Stroke Conference, Nashville, TN, N Okon, R Nelson, J Majersik, A Lesko, and See full citation in comments

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Endovascular treatment of tandem vascular occlusions in acute ischemic stroke., Ajit S Puri, Anna L Kühn, Hyon-Jo Kwon, Muhib Khan, Samuel Y Hou, Eugene Lin, Juyu Chueh, Imramsjah M J van der Bom, Guilherme Dabus, Italo Linfante, Matthew J Gounis, and Ajay K Wakhloo

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Abstract W P350: A Quality Enhancement Project to Capture Actual Weights Prior to Initiation of IV t-PA, Natalie Swearingen

Telemedicine in Urban Primary Stroke Centers Overcomes the "Weekend Effect" in Door-to-Needle Times for Acute lschemic Stroke Poster Presented at the International Stroke Conference, Nashville, TN, L Yanase, A Lesko, T Stuchiner, and E Baraban

Submissions from 2014

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Visualization of a small hidden intracranial aneurysm during endovascular thrombectomy for acute MCA occlusion., Anna Luisa Kühn, Samuel Y Hou, Gabriela Spilberg, and Ajay K Wakhloo

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Use of intermediate guide catheters as an adjunct in extracranial embolization to avoid onyx reflux into the anastomotic vasculature. A technical note., Ajit S Puri, Anna L Kühn, Samuel Y Hou, and Ajay K Wakhloo

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Double embolic protection during carotid artery stenting with persistent hypoglossal artery., Christine F Silva, Samuel Y Hou, Anna L Kühn, Richard H Whitten, and Ajay K Wakhloo

Submissions from 2013

Why Registries Matter: Impact of a Comprehensive Telestroke Registry on Clinical Quality Improvement Poster Presented at American Stroke Association Quality of Care and Outcomes Research Scientific Sessions, Baltimore, MD, Patrick Brown, A Lesko, E Baraban, E Fertig, and See full citation in comments

Does Age Play a Role in Providing Stroke Care to Acute lschemic Stroke Patients via Telestroke Poster Presented at American Academy of Neurology Annual Meeting, San Diego, CA, A Kansara, E Baraban, A Lesko, A Bhatt, and See full citation in comments

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Double embolic protection during carotid artery stenting with persistent hypoglossal artery., Christine F Silva, Samuel Y Hou, Anna L Kühn, Richard H Whitten, and Ajay K Wakhloo

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Reduction of coil mass artifacts in high-resolution flat detector conebeam CT of cerebral stent-assisted coiling., I M J van der Bom, Samuel Y Hou, A S Puri, G Spilberg, D Ruijters, P van de Haar, B Carelsen, S Vedantham, M J Gounis, and A K Wakhloo

Submissions from 2012

Impact of a Statewide Telestroke Network in Oregon Presentation at the American Telemedicine Association Annual Meeting and Trade Show, Orlando, FL, N Okon, E Baraban, A Lesko, M Schmitt, and See full citation in comments

Submissions from 2007

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SCN1A Seizure Disorders, IO Miller and Márcio A Sotero de Menezes

Submissions from 2006

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Brd4 links chromatin targeting to HPV transcriptional silencing., Shwu-Yuan Wu, A-Young Lee, Samuel Y Hou, Jongsook Kim Kemper, Hediye Erdjument-Bromage, Paul Tempst, and Cheng-Ming Chiang

Submissions from 2002

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Transcriptional activity among high and low risk human papillomavirus E2 proteins correlates with E2 DNA binding., Samuel Y Hou, Shwu-Yuan Wu, and Cheng-Ming Chiang

Submissions from 2000

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Alleviation of human papillomavirus E2-mediated transcriptional repression via formation of a TATA binding protein (or TFIID)-TFIIB-RNA polymerase II-TFIIF preinitiation complex., Samuel Y Hou, S Y Wu, T Zhou, M C Thomas, and C M Chiang

Submissions from 1999

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Isolation of mouse TFIID and functional characterization of TBP and TFIID in mediating estrogen receptor and chromatin transcription., S Y Wu, M C Thomas, S Y Hou, V Likhite, and C M Chiang