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Submissions from 2020

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Interim subgroup analysis for response by PD-L1 status of CLASSICAL-Lung, a phase Ib/II study of pepinemab (VX15/2503) in combination with avelumab in advanced NSCLC., Michael Rahman Shafique, Terrence Lee Fisher, Elizabeth E. Evans, John E. Leonard, Desa Rae Electa Pastore, Crystal L. Mallow, Ernest Smith, Andreas Schroder, Kevin M. Chin, Joseph Thaddeus Beck, Megan Ann Baumgart, Ramaswamy Govindan, Nashat Y. Gabrail, Rachel E Sanborn, Alexander I. Spira, Nagashree Seetharamu, Yanyan Lou, Aaron Scott Mansfield, Jonathan Wade Goldman, and Maurice Zauderer

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Interim results from a phase Ib/II study of pepinemab in combination with avelumab in advanced NSCLC patients following progression on prior systemic and/or anti-PDx therapies., Michael Rahman Shafique, Terrence Lee Fisher, Elizabeth E. Evans, John E. Leonard, Desa Rae Electa Pastore, Crystal L. Mallow, Ernest Smith, Andreas Schroder, Kevin M. Chin, J Thaddeus Beck, Megan Ann Baumgart, Ramaswamy Govindan, Nashat Y. Gabrail, Rachel E Sanborn, Alexander I. Spira, Nagashree Seetharamu, Yan Yan Lou, Aaron Scott Mansfield, Jonathan Wade Goldman, and Maurice Zauderer

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1020O A phase I, first-in-human, open-label, dose escalation study of MGD019, an investigational bispecific PD-1 x CTLA-4 DART® molecule in patients with advanced solid tumours, M Sharma, Rachel E Sanborn, GM Cote, JC Bendell, S Kaul, F Chen, A Berezhnoy, P Moore, E Bonvini, BJ Sumrow, and JJ Luke

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Lower Rates of Heart Failure and All-Cause Hospitalizations During Pulmonary Artery Pressure-Guided Therapy for Ambulatory Heart Failure: One-Year Outcomes From the CardioMEMS Post-Approval Study., David M Shavelle, Akshay S Desai, William T Abraham, Robert C Bourge, Nirav Raval, Lisa D Rathman, J Thomas Heywood, Rita A Jermyn, Jamie Pelzel, Orvar T Jonsson, Maria Rosa Costanzo, John D Henderson, Marie-Elena Brett, Philip B Adamson, Lynne W Stevenson, CardioMEMS Post-Approval Study Investigators, and Jacob Abraham (CardioMEMS Post-Approval Study Investigator)

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407 Preliminary safety, pharmacokinetics/pharmacodynamics, and antitumor activity of XmAb20717, a PD-1 x CTLA-4 bispecific antibody, in patients with advanced solid tumors, Elaine Shum, Adil Daud, Matthew Reilley, Yana Najjar, John Thompson, Joaquina Baranda, R Donald Harvey, Rom Leidner, Anthony Shields, Ezra Cohen, Roger Cohen, Alain Mita, Shubham Pant, Mark Stein, Bartosz Chmielowski, Siwen Hu-Lieskovan, Catherine Fleener, Ying Ding, Sowmya Chollate, Hector Avina, Jolene Shorr, Raphael Clynes, and Barbara Hickingbottom

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407 Preliminary safety, pharmacokinetics/pharmacodynamics, and antitumor activity of XmAb20717, a PD-1 x CTLA-4 bispecific antibody, in patients with advanced solid tumors, Elaine Shum, Adil Daud, Matthew Reilley, Yana Najjar, John Thompson, Joaquina Baranda, R Donald Harvey, Rom Leidner, Anthony Shields, Ezra Cohen, Alain Mita, Shubham Pant, Mark Stein, Bartosz Chmielowski, Siwen Hu-Lieskovan, Catherine Fleener, Ying Ding, Sowmya Chollate, Hector Avina, Jolene Shorr, Raphael Clynes, and Barbara Hickingbottom

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The Role of Hemodynamic Support in High-risk Percutaneous Coronary Intervention, Charles Simonton, Craig Thompson, Jason R Wollmuth, D Lynn Morris, and Thom G. Dahle

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Effect of various decontamination procedures on disposable N95 mask integrity and SARS-CoV-2 infectivity, Jeffrey Smith, Haley Hanseler, John Welle, Rogan Rattray, Mary Campbell, Tacy Brotherton, Tarsem Moudgil, Thomas F. Pack, Keith W Wegman, Shawn M. Jensen, Justin Jin, Carlo Bifulco, Scott A. Prahl, Bernard A Fox, and Nicholas L Stucky

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Effect of various decontamination procedures on disposable N95 mask integrity and SARS-CoV-2 infectivity., Jeffrey S Smith, Haley Hanseler, John Welle, Rogan Rattray, Mary Campbell, Tacy Brotherton, Tarsem Moudgil, Thomas F Pack, Keith Wegmann, Shawn Jensen, Justin Jin, Carlo B Bifulco, Scott A Prahl, Bernard A Fox, and Nicholas L Stucky

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What is the Cost-Effective Treatment for Melanoma Patients with a Positive Sentinel Node?, Hayley Standage, Alyssa R Hersh, Aaron Caughey, Matthew H Taylor, John Vetto, and Dale Han

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Breaking the Mold: Designing Health Plans That Do Not Impede Delivery of High-Value Care., Eric C Stecker, Lonny Reisman, Larry A Allen, and Tyler J Gluckman

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Response to anti-PD-1 and anti-LAG-3 immune checkpoint blockade (ICB) is associated with induction of pro-inflammatory Tregs, Elizabeth Sturgill, Courtney Mick, Johanna K. Kaufmann, and William L. Redmond

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Clinical activity of the RET inhibitor pralsetinib (BLU-667) in patients with RET fusion+ solid tumors., Vivek Subbiah, Mini I-Nan Hu, Justin F. Gainor, Aaron Scott Mansfield, Guzman Alonso, Matthew H Taylor, Viola Weijia Zhu, Pilar Garrido Lopez, Alessio Amatu, Robert C. Doebele, Philippe Alexandre Cassier, Bhumsuk Keam, Martin H. Schuler, Hui Zhang, Corinne Clifford, Michael Palmer, Jennifer Green, Christopher D. Turner, and Giuseppe Curigliano

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560 Alpha-tocopheryloxyacetic acid induces apoptosis of murine rhabdomyosarcoma in vitro while modulating innate and adaptive immune responses in vivo, Fernanda Szewc, Longzhen Song, Sean Rinella, Christopher Dubay, Emmanuel Akporiaye, William L. Redmond, and Christian Capitini

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560 Alpha-tocopheryloxyacetic acid induces apoptosis of murine rhabdomyosarcoma in vitro while modulating innate and adaptive immune responses in vivo, Fernanda Szewc, Longzhen Song, Sean Rinella, Christopher Dubay, Emmanuel Akporiaye, William L. Redmond, and Christian Capitini

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The Society for Immunotherapy of Cancer statement on best practices for multiplex immunohistochemistry (IHC) and immunofluorescence (IF) staining and validation., Janis M Taube, Guray Akturk, Michael Angelo, Elizabeth L Engle, Sacha Gnjatic, Shirley Greenbaum, Noah F Greenwald, Cyrus V Hedvat, Travis J Hollmann, Jonathan Juco, Edwin R Parra, Marlon C Rebelatto, David L Rimm, Jaime Rodriguez-Canales, Kurt A Schalper, Edward C Stack, Cláudia S Ferreira, Konstanty Korski, Ana Lako, Scott J Rodig, Emanuel Schenck, Keith E Steele, Michael J Surace, Michael T Tetzlaff, Katharina von Loga, Ignacio I Wistuba, Carlo Bifulco, and Society for Immunotherapy of Cancer (SITC) Pathology Task Force.

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A mutation-specific, single-arm, phase 2 study of dovitinib in patients with advanced malignancies., Matthew H Taylor, Ajjai S Alva, Timothy Larson, Sebastian Szpakowski, Das Purkaystha, Alpesh Amin, Linda Karpiak, and Sarina A Piha-Paul

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The LEAP program: lenvatinib plus pembrolizumab for the treatment of advanced solid tumors., Matthew H Taylor, Emmett V Schmidt, Corina Dutcus, Elaine M Pinheiro, Yasuhiro Funahashi, Gregory Lubiniecki, and Drew Rasco

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Loss of switch/sucrose non-fermenting complex protein expression in undifferentiated gastrointestinal and pancreatic carcinomas., Basile Tessier-Cloutier, David F Schaeffer, Julinor Bacani, Celia E Marginean, Steve Kalloger, Martin Köbel, and Cheng-Han Lee

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172 Increasing activation of human tumor-reactive T cells (CD39+CD103+CD8+) by gene silencing of PD1 with self-delivering RNAi INTASYL(TM), Colin Thalhofer, Ryan Montler, Melissa Maxwell, Dingxue Yan, James Cardia, Simon Fricker, Jacob Moses, Joshua Rios, Tarsem Moudgil, Bernard A Fox, Nick Morris, Richard Bryan Bell, and Andrew Weinberg

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172 Increasing activation of human tumor-reactive T cells (CD39+CD103+CD8+) by gene silencing of PD1 with self-delivering RNAi INTASYL(TM), Colin Thalhofer, Ryan Montler, Melissa Maxwell, Dingxue Yan, James Cardia, Simon Fricker, Jacob Moses, Joshua Rios, Tarsem Moudgil, Bernard A Fox, Nick Morris, Richard Bryan Bell, and Andrew D Weinberg

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Invasive Hemodynamic Assessment and Classification of In-Hospital Mortality Risk Among Patients With Cardiogenic Shock., Katherine L Thayer, Elric Zweck, Mohyee Ayouty, A Reshad Garan, Jaime Hernandez-Montfort, Claudius Mahr, Kevin J Morine, Sarah Newman, Lena Jorde, Jillian L Haywood, Neil M Harwani, Michele L Esposito, Carlos D Davila, Detlef Wencker, Shashank S Sinha, Esther Vorovich, Jacob Abraham, William O'Neill, James Udelson, Daniel Burkhoff, and Navin K Kapur

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PROCLAIM-CX-072: Analysis of patients with advanced solid tumors receiving long-term treatment with CX-072, a PD-L1 probody therapeutic, as a single agent or in combination with ipilimumab., Fiona Thistlethwaite, Aung Naing, Marta Gil-Martin, Patricia LoRusso, Manreet Randhawa, Ferry Eskens, Rachel E Sanborn, Nataliya Volodymyrivna Uboha, Daniel C. Cho, Alexander I. Spira, Igor Bondarenko, Elizabeth Ruth Plummer, Javier Garcia-Corbacho, Ivan Victoria, Javier Lavernia, Ignacio Melero, Elisabeth De Vries, William Garner, Hendrik-Tobias Arkenau, and Johanna C. Bendell

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Urelumab alone or in combination with rituximab in patients with relapsed or refractory B-cell lymphoma., John Timmerman, Charles Herbaux, Vincent Ribrag, Andrew D Zelenetz, Roch Houot, Sattva S Neelapu, Theodore Logan, Izidore S Lossos, Walter Urba, Gilles Salles, Radhakrishnan Ramchandren, Caron Jacobson, John Godwin, Cecilia Carpio, Deanne Lathers, Yali Liu, Jaclyn Neely, Satyendra Suryawanshi, Yoshinobu Koguchi, and Ronald Levy

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2020 ACC Expert Consensus Decision Pathway on Management of Bleeding in Patients on Oral Anticoagulants: A Report of the American College of Cardiology Solution Set Oversight Committee., Gordon F Tomaselli, Kenneth W Mahaffey, Adam Cuker, Paul P Dobesh, John U Doherty, John W Eikelboom, Roberta Florido, Tyler J Gluckman, William J Hucker, Roxana Mehran, Steven R Messé, Alexander C Perino, Fatima Rodriguez, Ravindra Sarode, Deborah M Siegal, and Barbara S Wiggins

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Targeting MerTK Enhances Adaptive Immune Responses After Radiation Therapy., Garth W Tormoen, Tiffany C Blair, Shelly Bambina, Gwen Kramer, Jason Baird, Ramtin Rahmani, John M Holland, Owen J T McCarty, Michael J Baine, Vivek Verma, Nima Nabavizadeh, Michael J Gough, and Marka Crittenden

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op Goals and Concerns Reported by Individuals with Inflammatory Bower Disease at Outpatient Gastroenterology Clinic Visits, Chang Sang Tse, Samir Shah, Damara Crate, Ridhima Oberai, Caroline Hwang, Arthur Ostrov, Donald Lum, Eugene Nelson, Brant Oliver, Aricca Van Citters, Megan Holthoff, Alice Kennedy, Jason Hou, Siddharth Signh, Alandra Weaver, Gil Melmed, Corey Siegel, and Welmoed van Deen

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PD-1 and PD-L1 Inhibitors: A Single Center Medication Assistance Program (MAP) Experience, Sarah Tu and Shuntao Cai

Device selection in TEVAR, Brant Ullery

Grand Rounds: Spinal protection strategies in contemporary aortic surgery, Brant Ullery

Management of abdominal aortic aneurysms with hostile infrarenal necks, Brant Ullery

Nearly 30 years of EVAR: Contemporary insights on long-term durability, Brant Ullery

Peripheral artery disease: Patient treatment, selection and device options in vascular surgery, Brant Ullery

Practical tools as healthcare emerges from the pandemic, Brant Ullery

Role of TEVAR in acute aortic syndromes, Brant Ullery

Supporting ruptured abdominal aortic aneurysm cases, Brant Ullery

Technical challenges in the treatment of ruptured AAAs. How to salvage the opportunity for ruptured EVAR, Brant Ullery

TEVAR in the fragile aorta, Brant Ullery

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Prophylactic Ruxolitinib for Cytokine Release Syndrome in Relapse/Refractory AML Patients Treated with Flotetuzumab., Geoffrey L. Uy, Michael P. Rettig, Stephanie Christ, Ibrahim Aldoss, Michael T. Byrne, Harry P. Erba, Martha L. Arellano, Matthew C. Foster, John E Godwin, Farhad Ravandi, Peter H. Sayre, Anjali S. Advani, Matthew J. Wieduwilt, Ashkan Emadi, Laura C. Michaelis, Patrick J. Stiff, Martin Wermke, Norbert Vey, Patrice Chevalier, Emmanuel Gyan, Christian Recher, Fabio Ciceri, Matteo Giovanni Carrabba, Antonio Curti, Geert Huls, Max S. Topp, Mojca Jongen-Lavrencic, John Muth, Teia Curtis, Mary Beth Collins, Erin Timmeny, Kuo Guo, Jian Zhao, Kathy Tran, Patrick Kaminker, Priyanka Patel, Ouiam Bakkacha, Kenneth Jacobs, Maya Kostova, Jennifer Seiler, Bob Lowenberg, Sergio Rutella, Roland B. Walter, Ezio Bonvini, Jan K. Davidson-Moncada, and John F. DiPersio

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TP53 abnormalities correlate with immune infiltration and associate with response to flotetuzumab immunotherapy in AML., Jayakumar Vadakekolathu, Catherine Lai, Stephen Reeder, Sarah E Church, Tressa Hood, Anbarasu Lourdusamy, Michael P Rettig, Ibrahim Aldoss, Anjali S Advani, John E Godwin, Matthew J Wieduwilt, Martha Arellano, John Muth, Tung On Yau, Farhad Ravandi, Kendra Sweet, Heidi Altmann, Gemma A Foulds, Friedrich Stölzel, Jan Moritz Middeke, Marilena Ciciarello, Antonio Curti, Peter J M Valk, Bob Löwenberg, Ivana Gojo, Martin Bornhäuser, John F DiPersio, Jan K Davidson-Moncada, and Sergio Rutella

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TP53 abnormalities correlate with immune infiltration and associate with response to flotetuzumab immunotherapy in AML., Jayakumar Vadakekolathu, Catherine Lai, Stephen Reeder, Sarah E Church, Tressa Hood, Anbarasu Lourdusamy, Michael P Rettig, Ibrahim Aldoss, Anjali S Advani, John E Godwin, Matthew J Wieduwilt, Martha Arellano, John Muth, Tung On Yau, Farhad Ravandi, Kendra Sweet, Heidi Altmann, Gemma A Foulds, Friedrich Stölzel, Jan Moritz Middeke, Marilena Ciciarello, Antonio Curti, Peter J M Valk, Bob Löwenberg, Ivana Gojo, Martin Bornhäuser, John F DiPersio, Jan K Davidson-Moncada, and Sergio Rutella

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Immune Senescence and Exhaustion Correlate with Response to Flotetuzumab, an Investigational CD123×CD3 Bispecific Dart® Molecule, in Acute Myeloid Leukemia, Jayakumar Vadakekolathu, Tung On Yau, Sarah E. Church, Michael P. Rettig, Ibarhim Aldoss, Geoffrey L. Uy, Norbert Vey, Ashkan Emadi, Peter H. Sayre, Roland B. Walter, Matthew C. Foster, Martha L. Arellano, John E Godwin, Matthew J. Wieduwilt, Michael T. Byrne, Laura C. Michaelis, Patrick J. Stiff, Matteo Giovanni Carrabba, Patrice Chevalier, Emmanuel Gyan, Christian Recher, Anjali S. Advani, Martin Wermke, Harry P. Erba, Fabio Ciceri, Geert Huls, Mojca Jongen-Lavrencic, Farhad Ravandi, Antonio Curti, Max S. Topp, John Muth, Patrick Kaminker, Bob Lowenberg, Ivana Gojo, Leo Luznik, John F. DiPersio, Jan K. Davidson-Moncada, and Sergio Rutella

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Global impact of the first coronavirus disease 2019 (COVID-19) pandemic wave on vascular services., Vascular and Endovascular Research Network (VERN) COVER study collaborative and Brant Ullery (Vascular and Endovascular Research Network (VERN) COVER study collaborative)

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Transoral robotic surgery and neck dissection for HPV-positive oropharyngeal carcinoma: Importance of nodal count in survival., Chi T Viet, Eric J Dierks, Allen C Cheng, Ashish Patel, Shu-Ching Chang, Marcus Couey, Amber L Watters, Thien Hoang, Hong D Xiao, Marka R Crittenden, Rom Leidner, Steven K Seung, Kristina H Young, and Richard Bryan Bell

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NKTR-214 immunotherapy synergizes with radiotherapy to stimulate systemic CD8, Joshua M Walker, Annah S Rolig, Deborah H Charych, Ute Hoch, Melissa Kasiewicz, Daniel Rose, Michael J McNamara, Ian F Hilgart-Martiszus, and William L. Redmond

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A multicenter trial of a shared DECision Support Intervention for Patients offered implantable Cardioverter-DEfibrillators: DECIDE-ICD rationale, design, Medicare changes, and pilot data., Bryan C Wallace, Larry A Allen, Christopher E Knoepke, Russell E Glasgow, Carmen L Lewis, Diane L Fairclough, Laura J Helmkamp, Monica D Fitzgerald, Wendy S Tzou, Daniel B Kramer, Paul D Varosy, Sanjaya K Gupta, John M Mandrola, Scott Brancato, Pamela N Peterson, and Daniel D Matlock

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PANEL DISCUSSION: Vaccine Development for COVID-19, Nathaniel Wang, Andrew J. Geall, and Andrew D Weinberg

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Agonist Abs to TNF Receptor Family Members, Andrew D Weinberg

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Can OX40 Agonists Increase the Potency of COVID-19 Vaccines?, Andrew D Weinberg

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Identifying Tumor-Reactive CD8 TIL in Patients with Solid Malignancies: Clinical Implications, Andrew D Weinberg

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Select Drug-Drug Interactions With Direct Oral Anticoagulants: JACC Review Topic of the Week., Barbara S Wiggins, Dave L Dixon, Ron R Neyens, Robert L Page, and Tyler J Gluckman

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Tumor infiltrating lymphocytes after neoadjuvant IRX-2 immunotherapy in oral squamous cell carcinoma: Interim findings from the INSPIRE trial., Gregory T Wolf, Siyu Liu, Emily Bellile, Maureen Sartor, Laura Rozek, Dafydd Thomas, Ariane Nguyen, Katie Zarins, Jonathan B McHugh, INSPIRE Trial Clinical Investigators, and R Bryan Bell

Embolization: thrombus, air, other, Jason R Wollmuth

Faculty panel - Intelligent intervention. Complex case examples incorporating lessons from SYNTAX 2, Jason R Wollmuth

High risk PCI program implementation and protocol development, Jason R Wollmuth

Live case panelist, case 3 & 4, Jason R Wollmuth

Live case panelist, case 5 & 6, Jason R Wollmuth

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New Advances in Avoiding Complications - Single Site Access in Impella-Assisted CTO PCI, Jason R Wollmuth

Retrograde CTO PCI, Jason R Wollmuth

Revascularization, support, and unloading: past, present, and future directions – protect IV: the synergy of MCS and complete revascularization, Jason R Wollmuth

Side branch access, Jason R Wollmuth

Single access Impella, Jason R Wollmuth

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Treating LV dysfunction – impact of complete revascularization on improvement in EF and heart failure, Jason R Wollmuth

Treating LV dysfunction – impact of complete revascularization on improvement in EF and heart failure, Jason R Wollmuth

Understanding how the use of routine oct workflow changes physician decisions: LightLab insights, Jason R Wollmuth

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Behavioral Health Integration and Outcomes that Matter to Patients: a Longitudinal Mixed-Methods Observational Study., Bill J. Wright, Lauren Broffman, Kayla Albrecht Mcmenamin, Kyle G Jones, Maggie Weller, Kristin Brown, Laura Jacobson, Nicole Bouranis, and Natalie Royal Kenton

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Facilitating the identification of patients hospitalized for acute myocardial infarction and heart failure and the assessment of their readmission risk through the Patient Navigator Program., Carolyn M Wu, Nancy M Albert, Tyler J Gluckman, Di Lu, Susan Rogers, Julie Mobayed, Shilpa Patel, and William S Weintraub

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Siponimod enriches regulatory T and B lymphocytes in secondary progressive multiple sclerosis., Qi Wu, Elizabeth A Mills, Qin Wang, Catherine A Dowling, Caitlyn Fisher, Britany Kirch, Steven K Lundy, David A Fox, Yang Mao-Draayer, AMS04 Study Group, James Bowden, and Stanley Cohan

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Introduction to the Immune System, Anti-tumor Immunity, and Immunotherapy., Kristina H Young

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Transcriptional Upregulation of NLRC5 by Radiation Drives STING- and Interferon-Independent MHC-I Expression on Cancer Cells and T Cell Cytotoxicity., Lauren Zebertavage, Alejandro F Alice, Marka R Crittenden, and Michael J. Gough

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COVID-19 lessons learned from China: disease management, clinical research and health policy, Wenhong Zhang, Sten H. Vermund, Xiaoyan Huang, and Kevin Ye

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Boosting NAD level suppresses inflammatory activation of PBMCs in heart failure., Bo Zhou, Dennis Ding-Hwa Wang, Yanhua Qiu, Sophia Airhart, Yaxin Liu, April Stempien-Otero, Kevin D O'Brien, and Rong Tian

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Blockade of the Phagocytic Receptor MerTK on Tumor-Associated Macrophages Enhances P2X7R-Dependent STING Activation by Tumor-Derived cGAMP., Yi Zhou, Mingjian Fei, Gu Zhang, Wei-Ching Liang, WeiYu Lin, Yan Wu, Robert Piskol, John Ridgway, Erin McNamara, Haochu Huang, Juan Zhang, Jaehak Oh, Jaina M Patel, Diana Jakubiak, Jeff Lau, Beth Blackwood, Daniel D Bravo, Yongchang Shi, Jianyong Wang, Hong-Ming Hu, Wyne P Lee, Rajiv Jesudason, Dewakar Sangaraju, Zora Modrusan, Keith R Anderson, Søren Warming, Merone Roose-Girma, and Minhong Yan

Submissions from 2019

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Association of Ambulatory Hemodynamic Monitoring With Clinical Outcomes in a Concurrent Matched Control Analysis., Jacob Abraham, Rupinder Bharmi, Orvar Jonsson, Guilherme H Oliveira, Andre Artis, Ali Valika, Robert Capodilupo, Philip B Adamson, Gregory Roberts, Nirav Dalal, Akshay S Desai, and Raymond L Benza

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Internal Jugular Vein as Alternative Access for Implantation of a Wireless Pulmonary Artery Pressure Sensor., Jacob Abraham, Patrick McCann, L Wang, Amanda Schnell Heringer, Jeff Paulsen, Jay Chappell, Joshua Remick, Daniel Westerdahl, Rebecca Lewis, Katherine Callis, Kateri Spinelli, and Liviu Klein

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Hemodynamic, Therapeutic, and Clinical Outcomes of Ambulatory Pressure-Guided Heart Failure Management, Jacob Abraham, L Wang, Rebecca Lewis, Katherine Callis, Joshua Remick, and Kateri Spinelli

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Current Landscape of Immunotherapy in Breast Cancer: A Review., Sylvia Adams, Margaret E Gatti-Mays, Kevin Kalinsky, Larissa A Korde, Elad Sharon, Laleh Amiri-Kordestani, Harry Bear, Heather L McArthur, Elizabeth Frank, Jane Perlmutter, David B Page, Benjamin Vincent, Jennifer F Hayes, James L Gulley, Jennifer K Litton, Gabriel N Hortobagyi, Stephen Chia, Ian Krop, Julia White, Joseph Sparano, Mary L Disis, and Elizabeth A Mittendorf

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Development and Initial Validation of the PROMIS®-Plus-HF Profile Measure., Faraz S Ahmad, Michael A Kallen, Karen E Schifferdecker, Kathleen L Carluzzo, Susan E Yount, Jill M Gelow, Peter A McCullough, Stephen E Kimmel, Elliot S Fisher, and David Cella

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Abstract 101: The Development and Initial Validation of PROMIS-Plus-HF Profile Measure, Faraz S. Ahmad, Michael A. Kallen, Karen E. Schifferdecker, Kathleen L. Carluzzo, Susan E. Yount, Jill M Gelow, Peter A. McCullough, Stephen E. Kimmel, Elliot S. Fisher, and David Cella

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Abstract 103: Clinical Process and Outcome Improvements Based on Within Site Communication: Insights from the Patient Navigator Acute Myocardial Infarction and Heart Failure Program, Nancy M. Albert, Tyler J Gluckman, Robert McNamara, Gregg C. Fonarow, Adnan Malik, Ralph G. Brindis, Di Lu, Smita Negi, Susan Rogers, and Julie Mobayed

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The Association of Patient Navigator Program Features and Hospital Strategies with Processes and Outcome Metrics in Acute Myocardial Infarction and Heart Failure, NM Albert, Tyler J Gluckman, RL McNamara, GC Fonarow, A Malik, RG Brindis, D Lu, S Negi, S Rogers, and J Mobayed

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Examining the Prevalence of Adverse Childhood Experiences and Associated Cardiovascular Disease Risk Factors Among Low-Income Uninsured Adults., Heidi Allen, Bill J. Wright, Keri B Vartanian, Kristen Dulacki, and Hsin-Fang Li

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Viral Targeting of Non-Muscle-Invasive Bladder Cancer and Priming of Antitumor Immunity Following Intravesical Coxsackievirus A21., Nicola E Annels, David Mansfield, Mehreen Arif, Carmen Ballesteros-Merino, Guy R Simpson, Mick Denyer, Sarbjinder S Sandhu, Alan A Melcher, Kevin J Harrington, Bronwyn Davies, Gough Au, Mark Grose, Izhar Bagwan, Bernard A Fox, Richard Vile, Hugh Mostafid, Darren Shafren, and Hardev S Pandha

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Clinician's Guide to the Updated ABCs of Cardiovascular Disease Prevention: A Review Part 1., Kelly Arps, Vincent A Pallazola, Rhanderson Cardoso, Joseph Meyer, Richard Jones, Jacqueline Latina, Tyler J Gluckman, Neil J Stone, Roger S Blumenthal, and John W McEvoy

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Clinician's Guide to the Updated ABCs of Cardiovascular Disease Prevention: A Review Part 2., Kelly Arps, Vincent A Pallazola, Rhanderson Cardoso, Joseph Meyer, Richard Jones, Jacqueline Latina, Tyler J Gluckman, Neil J Stone, Roger S Blumenthal, and John W McEvoy

Perspectives in immunotherapy: meeting report from the "Immunotherapy Bridge 2018" (28-29 November, 2018, Naples, Italy)., Paolo A Ascierto, Carlo Bifulco, Luigi Buonaguro, Leisha A Emens, Robert L Ferris, Bernard A Fox, Greg M Delgoffe, Jérôme Galon, Cesare Gridelli, Marco Merlano, Paul Nathan, Kunle Odunsi, Hideho Okada, Chrystal M Paulos, Sandro Pignata, Kurt A Schalper, Stefani Spranger, Giampaolo Tortora, Hassane Zarour, Lisa H Butterfield, and Igor Puzanov

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Pre-Analytic Variables and Tissue Stewardship for Reliable Next-Generation Sequencing (NGS) Clinical Analysis., Paolo A Ascierto, Carlo Bifulco, Giuseppe Palmieri, Solange Peters, and Nikoletta Sidiropoulos

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Device-detected congestion is associated with worse patient-reported outcomes in heart failure., Jonathan P Auld, James O Mudd, Jill M Gelow, Karen S Lyons, Shirin O Hiatt, and Christopher S Lee

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Contemporary Techniques in Orbital Reconstruction: A Review of the Literature and Report of a Case Combining Surgical Navigation, Computer-Aided Surgical Simulation, and a Patient-Specific Implant., Iman Azarmehr, Kasper Stokbro, Richard Bryan Bell, and Torben Thygesen

High Tech, Meet High Touch, James G Beckerman

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Play Smart Youth Heart Screening Program Reduces False-Positive Rates for Screening Electrocardiograms, James G Beckerman, M Wang, Lydia Hibsch, and Nancy Davis

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Toward a comprehensive view of cancer immune responsiveness: a synopsis from the SITC workshop., Davide Bedognetti, Michele Ceccarelli, Lorenzo Galluzzi, Rongze Lu, Karolina Palucka, Josue Samayoa, Stefani Spranger, Sarah Warren, Kwok-Kin Wong, Elad Ziv, Diego Chowell, Lisa M Coussens, Daniel D De Carvalho, David G DeNardo, Jérôme Galon, Howard L Kaufman, Tomas Kirchhoff, Michael T Lotze, Jason J Luke, Andy J Minn, Katerina Politi, Leonard D Shultz, Richard Simon, Vésteinn Thórsson, Joanne B Weidhaas, Maria Libera Ascierto, Paolo Antonio Ascierto, James M Barnes, Valentin Barsan, Praveen K Bommareddy, Adrian Bot, Sarah E Church, Gennaro Ciliberto, Andrea De Maria, Dobrin Draganov, Winson S Ho, Heather M McGee, Anne Monette, Joseph F Murphy, Paola Nisticò, Wungki Park, Maulik Patel, Michael Quigley, Laszlo Radvanyi, Harry Raftopoulos, Nils-Petter Rudqvist, Alexandra Snyder, Randy F Sweis, Sara Valpione, Lisa H Butterfield, Mary L Disis, Bernard A Fox, Alessandra Cesano, and Francesco M Marincola

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Correction to: Toward a comprehensive view of cancer immune responsiveness: a synopsis from the SITC workshop., Davide Bedognetti, Michele Ceccarelli, Lorenzo Galluzzi, Rongze Lu, Karolina Palucka, Josue Samayoa, Stefani Spranger, Sarah Warren, Kwok-Kin Wong, Elad Ziv, Diego Chowell, Lisa M Coussens, Daniel D De Carvalho, David G DeNardo, Jérôme Galon, Howard L Kaufman, Tomas Kirchhoff, Michael T Lotze, Jason J Luke, Andy J Minn, Katerina Politi, Leonard D Shultz, Richard Simon, Vésteinn Thorsson, Joanne B Weidhaas, Maria Libera Ascierto, Paolo Antonio Ascierto, James M Barnes, Valentin Barsan, Praveen K Bommareddy, Adrian Bot, Sarah E Church, Gennaro Ciliberto, Andrea De Maria, Dobrin Draganov, Winson S Ho, Heather M McGee, Anne Monette, Joseph F Murphy, Paola Nisticò, Wungki Park, Maulik Patel, Michael Quigley, Laszlo Radvanyi, Harry Raftopoulos, Nils-Petter Rudqvist, Alexandra Snyder, Randy F Sweis, Sara Valpione, Roberta Zappasodi, Lisa H Butterfield, Mary L Disis, Bernard A Fox, Alessandra Cesano, and Francesco M Marincola

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Do annuloplasty rings designed to treat ischemic/functional mitral regurgitation alter left-ventricular dimensions in the acutely ischemic ovine heart?, Wolfgang Bothe, John-Peder Escobar Kvitting, Manuel K Rausch, Tomasz A Timek, Julia C Swanson, David H Liang, Mario Walther, Ellen Kuhl, Neil B Ingels, and D Craig Miller

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Advances in drug delivery for post-surgical cancer treatment., Lin-Lin Bu, Junjie Yan, Zejun Wang, Huitong Ruan, Qian Chen, Vivienne Gunadhi, Richard Bryan Bell, and Zhen Gu

Seniors at risk for falling after emergency room visit (SAFER): When are falls a proxy for unmet needs and frailty?, Colleen Casey, MB Kuebrich, K Engstrom, and A Fox

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Abstract 9573: Advance Care Planning and Prognosis Education in Patients With Heart Failure: Insights from the NCDR PINNACLE Registry, Casey Cavanagh, Lindsey Rosman, Philip Chui, Karl E. Minges, Nihar R. Desai, Sarah Goodlin, Savitri Fedson, John A. Spertus, Tyler J Gluckman, Yang Song, Alexander Turchin, Gheorghe Doros, Jane J. Lee, and Matthew M. Burg

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Simultaneous T Cell Activation and Macrophage Polarization to Promote Potent Tumor Suppression by Iron Oxide-Embedded Large-Pore Mesoporous Organosilica Core-Shell Nanospheres., Lin Chen, Xiaobo Ma, Meng Dang, Heng Dong, Hong-Ming Hu, Xiaodan Su, Wenfei Liu, Qing Wang, Yongbin Mou, and Zhaogang Teng

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Tumor-released autophagosomes induces CD4, Yong-Qiang Chen, Peng-Cheng Li, Ning Pan, Rong Gao, Zhi-Fa Wen, Tian-Yu Zhang, Fang Huang, Fang-Yuan Wu, Xi-Long Ou, Jin-Ping Zhang, Xue-Jun Zhu, Hong-Ming Hu, Kang Chen, Yun-Lang Cai, and Li-Xin Wang

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Identifying underlying constructs of childhood adversity in a low-income population., Hannah Cohen-Cline, Kyle G Jones, Sheetal Kulkarni-Rajasekhara, Heather M Polonsky, and Keri B Vartanian