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Submissions from 2021

Heart to heart: cardiology and nephrology discuss heart failure management, A Ross and C Kassakian

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Evaluation of Shared Experiences Among Patients and Providers Following Behavioral Health Integration in Primary Care., Natalie Royal Kenton, Nicole Bouranis, Emily J Cox, Laura Jacobson, and Bill J. Wright

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GM-CSF drives myelopoiesis, recruitment and polarisation of tumour-associated macrophages in cholangiocarcinoma and systemic blockade facilitates antitumour immunity., Luis I Ruffolo, Katherine M Jackson, Peyton C Kuhlers, Benjamin S Dale, Nathania M Figueroa Guilliani, Nicholas A Ullman, Paul R Burchard, Shuyang S Qin, Peter G Juviler, Jessica Millian Keilson, Ashley B Morrison, Mary Georger, Rachel Jewell, Laura M Calvi, Timothy M Nywening, Michael R O'Dell, Aram F Hezel, Luis De Las Casas, Gregory B Lesinski, Jen Jen Yeh, Roberto Hernandez-Alejandro, Brian A Belt, and David C Linehan

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Amivantamab in Post-platinum EGFR Exon 20 Insertion Mutant Non-small Cell Lung Cancer, JK Sabari, CA Shu, K Park, N Leighl, P Mitchell, S Kim, J Lee, D Kim, S Viteri, A Spira, J Han, J Trigo, CK Lee, KH Lee, N Girard, T Yang, K Goto, Rachel E Sanborn, JC Yang, J Xie, A Roshak, M Thayu, RE Knoblauch, and BC Cho

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Excess Mortality Among Patients Hospitalized During the COVID-19 Pandemic., Amber K Sabbatini, Ari Robicsek, Shih-Ting Chiu, and Ty J Gluckman

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Anti-GBM nephritis with mesangial IgA deposits after SARS-CoV-2 mRNA vaccination., Allan Sacker, Vanderlene Kung, and Nicole Andeen

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601 Sequencing immunotherapy before lymphatic ablation unleashes cDC1-dependent antitumor immunity in HNSCC, Robert Saddami-Konefka, Shawn M. Jensen, Bernard A Fox, and See all authors in comments

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A simplified approach to identification of risk status in patients with atherosclerotic cardiovascular disease, Aparna Sajja, Hsin-Fang Li, Kateri Spinelli, Amir Ali, Salim S. Virani, Seth S. Martin, and Tyler J Gluckman

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Concordance of LDL-cholesterol levels between the Friedewald, Martin/Hopkins, and Sampson equations in patients with atherosclerotic cardiovascular disease, Aparna Sajja, Hsin-Fang Li, Kateri Spinelli, Salim S. Virani, Seth S. Martin, and Tyler J Gluckman

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Physical Activity Patterns and Relationships With Cognitive Function in Patients With Breast Cancer Before, During, and After Chemotherapy in a Prospective, Nationwide Study., Elizabeth A Salerno, Eva Culakova, Amber S Kleckner, Charles E Heckler, Po-Ju Lin, Charles E Matthews, Alison Conlin, Lora Weiselberg, Jerry Mitchell, Karen M Mustian, and Michelle C Janelsins

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RAMOSE: An Open-Label Randomized Phase II Study of Osimertinib with or without Ramucirumab in TKI-Naïve EGFR-Mutant Metastatic NSCLC, A Saltos, C Baik, Rachel E Sanborn, E Shum, C Kim, R Hall, MJ Fidler, CA Shu, G Otterson, J Patel, K Wong, N Hanna, J Gray, J Heymach, and X Le

Immunotherapy Combos: LAG-3, TIM-3, TIGIT, OX-40, Rachel E Sanborn

OncLive Data Review: ESMO Congress 2021, Rachel E Sanborn

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A phase 1 dose-escalation study of a PD-L1xCD27 bispecific antibody CDX-527 in patients with advanced malignancies., Rachel E Sanborn, Rodolfo E. Bordoni, and See author list in comments

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Sanborn and Gaffar Share Clinical and Economic Treatment Insights in NSCLC, Rachel E Sanborn and Yousuf A. Gaffar

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CX-072 (pacmilimab), a Probody PD-L1 inhibitor, in combination with ipilimumab in patients with advanced solid tumors (PROCLAIM-CX-072): a first-in-human, dose-finding study., Rachel E Sanborn, Omid Hamid, Elisabeth Ge de Vries, Patrick A Ott, Javier Garcia-Corbacho, Valentina Boni, Johanna Bendell, Karen A Autio, Daniel C Cho, Ruth Plummer, Mark Stroh, Lawrence Lu, and Fiona Thistlethwaite

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398 neoIRX: a phase II trial of locoregional cytokine therapy to promote immunologic priming and clinical response to neoadjuvant pembrolizumab plus chemotherapy in triple negative breast cancer (TNBC), Katherine Sanchez, Alison Conlin, Parvin Peddi, Sasha Stanton, Janet Ruzich, Kelly S Perlewitz, Yaping Wu, Nikki Moxon, Staci Mellinger, Zhaoyu Sun, William L. Redmond, and David B Page

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OT1-18-03. The neoIRX trial:locoregional cytokine therapy to promote immunologic priming and enhanced response to neoadjuvant pembrolizumab plus chemotherapy in triple negative breast cancer (TNBC), Katherine Sanchez, Alison Conlin, Parvin Peddi, Sasha Stanton, Janet Ruzich, Kelly S Perlewitz, Yaping Wu, Nikki Moxon, Staci Mellinger, Zhaoyu Sun, William L. Redmond, and David B Page

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Multiplex immunofluorescence to measure dynamic changes in tumor-infiltrating lymphocytes and PD-L1 in early-stage breast cancer., Katherine Sanchez, Isaac Kim, Brie Chun, Joanna Pucilowska, William L. Redmond, Walter Urba, Maritza Martel, Yaping Wu, Mary Campbell, Zhaoyu Sun, Gary Grunkemeier, Shu-Ching Chang, Brady Bernard, and David B Page

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Lifileucel, a Tumor-Infiltrating Lymphocyte Therapy, in Metastatic Melanoma., Amod A Sarnaik, Omid Hamid, Nikhil I Khushalani, Karl D Lewis, Theresa Medina, Harriet M Kluger, Sajeve S Thomas, Evidio Domingo-Musibay, Anna C Pavlick, Eric D Whitman, Salvador Martin-Algarra, Pippa Corrie, Brendan D Curti, Judit Oláh, Jose Lutzky, Jeffrey S Weber, James M G Larkin, Wen Shi, Toshimi Takamura, Madan Jagasia, Harry Qin, Xiao Wu, Cecile Chartier, Friedrich Graf Finckenstein, Maria Fardis, John M Kirkwood, and Jason A Chesney

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Facebook Live: Environmental Stewardship through a Clinical Lens, Elizabeth Schenk and Brian B. Chesebro

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A Phase Ib/II Study of Pepinemab in Combination with Avelumab in Advanced Non-Small Cell Lung Cancer., Michael R Shafique, Terrence L Fisher, Elizabeth E Evans, John E Leonard, Desa Rae E Pastore, Crystal L Mallow, Ernest Smith, Vikas Mishra, Andreas Schröder, Kevin M Chin, Joseph T Beck, Megan A Baumgart, Ramaswamy Govindan, Nashat Y Gabrail, Alexander I Spira, Nagashree Seetharamu, Yanyan Lou, Aaron S Mansfield, Rachel E Sanborn, Jonathan W Goldman, and Maurice Zauderer

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Management of spontaneous coronary artery dissection complicated by cardiogenic shock using mechanical circulatory support with the Impella device., Shilpa Sharma, Samantha Polak, Zachary George, John LeDoux, Richard Sohn, Adam Stys, Cathy Jeon, Yousef Ghazzawi, and Malissa Wood

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A platform for locoregional T-cell immunotherapy to control HNSCC recurrence following tumor resection., Shay Sharon, Jason R Baird, Shelly Bambina, Gwen Kramer, Tiffany C Blair, Shawn M Jensen, Rom S Leidner, R Bryan Bell, Nardy Casap, Marka R Crittenden, and Michael J Gough

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Explant Modeling of the Immune Environment of Head and Neck Cancer., Shay Sharon, Thomas Duhen, Shelly Bambina, Jason Baird, Rom Leidner, Bryan Bell, Nardy Casap, Marka Crittenden, Swetha Vasudevan, Maria Jubran, Nataly Kravchenko-Balasha, and Michael Gough

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Open-label, phase II study of ladiratuzumab vedotin (LV) for castration-resistant prostate cancer (SGNLVA-005, trial-in-progress)., Amna Falak Sher, Justine Yang Bruce, Nashat Y. Gabrail, Ian Churchill Anderson, Anna Patrikidou, Rachel E Sanborn, Jae Yong Cho, Arielle Shebay Lee, Jong-Seok Lee, Louise M. Nott, Do-Youn Oh, Sang Cheul Oh, Sung Yong Oh, Yinghui Wang, Zejing Wang, and Troy H. Guthrie

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1193MO - Amivantamab plus lazertinib in post-osimertinib, post-platinum chemotherapy EGFR-mutant non-small cell lung cancer (NSCLC): Preliminary results from CHRYSALIS-2, CA Shu, K Goto, Y Ohe, B Besse, K Park, Y Wang, F Griesinger, JC Yang, E Felip, Rachel E Sanborn, R Bernabe Caro, JM Bauml, J Chen, E Fennema, J Mahoney, L Trani, RE Knoblauch, M Thayu, and BC Chou

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523 Preliminary clinical experience with XmAb20717, a PD-1 x CTLA-4 bispecific antibody, in patients with advanced solid tumors, Elaine Shum, Rom Leidner, and See full list of authors in comments

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Multicenter, double-blind, placebo-controlled trial of seviprotimut-L polyvalent melanoma vaccine in patients with post-resection melanoma at high risk of recurrence., Craig L Slingluff, Karl D Lewis, Robert Andtbacka, John Hyngstrom, Mohammed Milhem, Svetomir N Markovic, Tawnya Bowles, Omid Hamid, Leonel Hernandez-Aya, Joel Claveau, Sekwon Jang, Prejesh Philips, Shernan G Holtan, Montaser F Shaheen, Brendan Curti, William Schmidt, Marcus O Butler, Juan Paramo, Jose Lutzky, Arvinda Padmanabhan, Sajeve Thomas, Daniel Milton, Andrew Pecora, Takami Sato, Eddy Hsueh, Suprith Badarinath, John Keech, Sujith Kalmadi, Pallavi Kumar, Robert Weber, Edward Levine, Adam Berger, Anna Bar, J Thaddeus Beck, Jeffrey B Travers, Catalin Mihalcioiu, Brian Gastman, Peter Beitsch, Suthee Rapisuwon, John Glaspy, Edward C McCarron, Vinay Gupta, Deepti Behl, Brent Blumenstein, and Joanna J Peterkin

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Clinical outcomes of patients with multiple sclerosis treated with ocrelizumab in a US community MS center: an observational study., Kyle Smoot, Chiayi Chen, Tamela Stuchiner, Lindsay Lucas, Lois Grote, and Stanley Cohan

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Tumor-associated autoantibodies from mouse breast cancer models are found in serum of breast cancer patients., Sasha Stanton, Ekram Gad, Erik Ramos, Lauren Corulli, James Annis, Jennifer Childs, Hiroyuki Katayama, Samir Hanash, Jeffrey Marks, and Mary L Disis

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1556 - Retinoid X receptor agonists enhances Th1 antigen-specific and polyfunctional T cells with the HER2-IGFBP2-IGF1R vaccine, Sasha Stanton, Erin Rodmaker, Nicholas Drovetto, Lauren Corulli, Flonia Levy, Venkatram Atigadda, Clinton Grubbs, Romaine Fernando, Shizuko Sei, and Mary L. Disis

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Global Proteomic Profiling Identifies Novel Prognostic Factors in Undifferentiated Leukemia Blasts from Patients with NPM1 Mutations: A Previously Unreported Approach to Biomarker Discovery from the Fred Hutch and SWOG, Derek Stirewalt, John E Godwin, and See full list of authors in comments

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Facebook Live: New Year, New You: Personalize your plate and start moving, Niki Strealy and Stacey Cochran

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Galectin-3 inhibition with belapectin combined with anti-OX40 therapy reprograms the tumor microenvironment to favor anti-tumor immunity., Elizabeth Sturgill, Annah S Rolig, Stefanie N Linch, Courtney Mick, Melissa Kasiewicz, Zhaoyu Sun, Peter G Traber, Harold Shlevin, and William L. Redmond

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Pralsetinib for patients with advanced or metastatic RET-altered thyroid cancer (ARROW): a multi-cohort, open-label, registrational, phase 1/2 study., Vivek Subbiah, Mimi I Hu, Lori J Wirth, Martin Schuler, Aaron S Mansfield, Giuseppe Curigliano, Marcia S Brose, Viola W Zhu, Sophie Leboulleux, Daniel W Bowles, Christina S Baik, Douglas Adkins, Bhumsuk Keam, Ignacio Matos, Elena Garralda, Justin F Gainor, Gilberto Lopes, Chia-Chi Lin, Yann Godbert, Debashis Sarker, Stephen G Miller, Corinne Clifford, Hui Zhang, Christopher D Turner, and Matthew H Taylor

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Developing an enhanced 7-color multiplex IHC protocol to dissect immune infiltration in human cancers., Zhaoyu Sun, Richard Nyberg, Yaping Wu, Brady Bernard, and William L. Redmond

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Safety and Efficacy of Pembrolizumab in Combination with Acalabrutinib in Advanced Head and Neck Squamous Cell Carcinoma: Phase 2 Proof-of-Concept Study., Matthew H Taylor, Courtney B Betts, Lauren Maloney, Eric Nadler, Alain Algazi, Michael J Guarino, John Nemunaitis, Antonio Jimeno, Priti Patel, Veerendra Munugalavadla, Lin Tao, Douglas Adkins, Jerome H Goldschmidt, Ezra E W Cohen, and Lisa M Coussens

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Encorafenib and binimetinib with or without nivolumab in treating patients with metastatic radioiodine refractory BRAF V600 mutant thyroid cancer., Matthew H Taylor, Rom Leidner, Richard Bryan Bell, Bernard A Fox, and See full authors list in comments

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The LEAP program: lenvatinib plus pembrolizumab for the treatment of advanced solid tumors., Matthew H Taylor, Emmett V Schmidt, Corina Dutcus, Elaine M Pinheiro, Yasuhiro Funahashi, Gregory Lubiniecki, and Drew Rasco

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Correlation of Performance Status and Neutrophil-Lymphocyte Ratio With Efficacy in Radioiodine-Refractory Differentiated Thyroid Cancer Treated With Lenvatinib., Matthew H Taylor, Shunji Takahashi, Jaume Capdevila, Makoto Tahara, Sophie Leboulleux, Naomi Kiyota, Corina E Dutcus, Ran Xie, Bruce Robinson, Steven I Sherman, Mouhammed Amir Habra, Rossella Elisei, and Lori J Wirth

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Intratumoral Plasmid IL12 Expands CD8, Melinda L Telli, Hiroshi Nagata, Irene Wapnir, Chaitanya R Acharya, Kaitlin Zablotsky, Bernard A Fox, Carlo Bifulco, Shawn M. Jensen, Carmen Ballesteros-Merino, Mai Hope Le, Robert H Pierce, Erica Browning, Reneta Hermiz, Lauren Svenson, Donna Bannavong, Kim Jaffe, Jendy Sell, Kellie Malloy Foerter, David A Canton, Christopher G Twitty, Takuya Osada, H Kim Lyerly, and Erika J Crosby

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CardioMEMS guided treatment of chronic HF patients supported with a HeartMate LVAD: INTELLECT 2-HF study, V Thohan, Jacob Abraham, A Burdof, DJ Farrar, N Dirckx, AT Baker, and SG Drakos

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A Caenorhabditis elegans behavioral assay distinguishes early stage prostate cancer patient urine from controls, Morgan Thompson, Noemi Sarabia Feria, Ally Yoshioka, Eugene Tu, Fehmi Civitci, Suzanne Estes, and Josiah T Wagner

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Evaluation and optimization of blanket production from recycled polyethylene terephthalate based on the coordination of environment, economy, and society., Shu Tian, Hongrui Tang, Qingsong Wang, Xueliang Yuan, Qiao Ma, and Mansen Wang

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Abemaciclib in Combination With Endocrine Therapy for Patients With Hormone Receptor-Positive, HER2-Negative Metastatic Breast Cancer: A Phase 1b Study., Sara M Tolaney, Muralidhar Beeram, J Thaddeus Beck, Alison Conlin, E Claire Dees, Shannon L Puhalla, Brent N Rexer, Howard A Burris, Komal Jhaveri, Teresa Helsten, Carlos Becerra, Kevin Kalinsky, Kathleen N Moore, Allison M Manuel, Andrew Lithio, Gregory L Price, Sonya C Chapman, Lacey M Litchfield, and Matthew P Goetz

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583 Exploring the potential of T cell acute lymphoblastic leukemia (T-ALL) for generating leukemia-specific T cell responses that can be therapeutically harnessed with immunotherapy, Todd Triplett, Andrew D Weinberg, and See full list of authors in comments

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Supportive Management of Patients with Advanced Pheochromocytomas and Paragangliomas Receiving PRRT., Erica S Tsang, Gayle Funk, Janet Leung, Grace Kalish, and Hagen F Kennecke

Strategic interventional approach to femoropopliteal occlusive disease, Brant Ullery

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Long-Term Outcomes of Intra-Arterial Chemotherapy for Progressive or Unresectable Pilocytic Astrocytomas: Case Studies., Kutluay Uluc, Dominic A Siler, Ricardo Lopez, Csanad Varallyay, Joao Prola Netto, Jenny Firkins, Cindy Lacy, Amy Huddleston, Prakash Ambady, and Edward A Neuwelt

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Should Airbag Backpacks Be Standard Avalanche Safety Equipment?, Christopher Van Tilburg

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Associations of Uncertainty With Psychological Health and Quality of Life in Older Adults With Advanced Cancer., Haydee C Verduzco-Aguirre, Dilip Babu, Supriya G Mohile, Javier Bautista, Huiwen Xu, Eva Culakova, Beverly Canin, Yingzi Zhang, Megan Wells, Ronald M Epstein, Paul Duberstein, Colin McHugh, William Dale, Alison Conlin, James Bearden, Jeffrey Berenberg, Mohamedtaki Tejani, and Kah Poh Loh

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Pediatric Endoscopy Quality Improvement Network (PEnQuIN) Quality Standards and Indicators for Pediatric Endoscopists and Endoscopists in Training: A Joint NASPGHAN/ESPGHAN Guideline., Catharine M Walsh, Jenifer R Lightdale, Ian H Leibowitz, Diana G Lerner, Quin Y Liu, David R Mack, Petar Mamula, Priya Narula, Salvatore Oliva, Matthew R Riley, Joel R Rosh, Marta Tavares, Elizabeth C Utterson, Jorge Amil-Dias, Patrick Bontems, Herbert Brill, Nicholas M Croft, Douglas S Fishman, Raoul I Furlano, Peter M Gillett, Iva Hojsak, Matjaž Homan, Hien Q Huynh, Kevan Jacobson, Lusine Ambartsumyan, Anthony R Otley, Robert E Kramer, Graham A McCreath, Veronik Connan, Mike A Thomson, and PEnQuIN Working Group

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Overview of the Pediatric Endoscopy Quality Improvement Network (PEnQuIN) Quality Standards and Indicators for Pediatric Endoscopy: A Joint NASPGHAN/ESPGHAN Guideline., Catharine M Walsh, Jenifer R Lightdale, David R Mack, Jorge Amil-Dias, Patrick Bontems, Herbert Brill, Nicholas M Croft, Douglas S Fishman, Raoul I Furlano, Peter M Gillett, Iva Hojsak, Matjaž Homan, Hien Q Huynh, Kevan Jacobson, Ian H Leibowitz, Diana G Lerner, Quin Y Liu, Petar Mamula, Priya Narula, Salvatore Oliva, Matthew R Riley, Joel R Rosh, Marta Tavares, Elizabeth C Utterson, Lusine Ambartsumyan, Anthony R Otley, Robert E Kramer, Veronik Connan, Graham A McCreath, Mike A Thomson, and PEnQuIN Working Group

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Cryoballoon Ablation as Initial Therapy for Atrial Fibrillation., Oussama M Wazni, Gopi Dandamudi, Nitesh Sood, Robert Hoyt, Jaret Tyler, Sarfraz Durrani, Mark Niebauer, Kevin Makati, Blair Halperin, Andre Gauri, Gustavo Morales, Mingyuan Shao, Jeffrey Cerkvenik, Rachelle E Kaplon, Steven E Nissen, and STOP AF First Trial Investigators

OX40 agonists enhance tumor Ag-specific T cell responses in cancer patients, Andrew D Weinberg

Enriching for Tumor-Reactive CD8 TIL with CD39/103 Markers: Implications for TIL Therapy, Andrew D. Weinberg

Adipocytes as Anticancer Drug Delivery Depot, D Wen, J Wang, and Z Gu

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Genetic deletion of Polo-like kinase 2 reduces alpha-synuclein serine-129 phosphorylation in presynaptic terminals but not Lewy bodies., Leah J Weston, Teresa L Stackhouse, Kateri Spinelli, Sydney W Boutros, Elizabeth P Rose, Valerie R Osterberg, Kelvin C Luk, Jacob Raber, Tamily A Weissman, and Vivek K Unni

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Tumor Microenvironment, HLA Class I and APM Expression in HPV-Negative Oral Squamous Cell Carcinoma., Claudia Wickenhauser, Daniel Bethmann, Matthias Kappler, Alexander Walter Eckert, André Steven, Jürgen Bukur, Bernard Aloysius Fox, Jana Beer, and Barbara Seliger

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Phase I/II study of nivolumab plus vorolanib in patients with thoracic malignancies: Interim efficacy of the SCLC and primary refractory NSCLC cohorts, and safety data across all cohorts., Selina K. Wong, Jennifer G. Whisenant, Rachel E Sanborn, and See list of authors in comments

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Global Chronic Total Occlusion Crossing Algorithm: JACC State-of-the-Art Review., Eugene B Wu, Emmanouil S Brilakis, Kambis Mashayekhi, Etsuo Tsuchikane, Khaldoon Alaswad, Mario Araya, Alexandre Avran, Lorenzo Azzalini, Avtandil M Babunashvili, Baktash Bayani, Michael Behnes, Ravinay Bhindi, Nicolas Boudou, Marouane Boukhris, Nenad Z Bozinovic, Leszek Bryniarski, Alexander Bufe, Christopher E Buller, M Nicholas Burke, Achim Buttner, Pedro Cardoso, Mauro Carlino, Ji-Yan Chen, Evald Hoej Christiansen, Antonio Colombo, Kevin Croce, Felix Damas de Los Santos, Tony de Martini, Joseph Dens, Carlo di Mario, Kefei Dou, Mohaned Egred, Basem Elbarouni, Ahmed M ElGuindy, Javier Escaned, Sergey Furkalo, Andrea Gagnor, Alfredo R Galassi, Roberto Garbo, Gabriele Gasparini, Junbo Ge, Lei Ge, Pravin Kumar Goel, Omer Goktekin, Nieves Gonzalo, Luca Grancini, Allison Hall, Franklin Leonardo Hanna Quesada, Colm Hanratty, Stefan Harb, Scott A Harding, Raja Hatem, Jose P S Henriques, David Hildick-Smith, Jonathan M Hill, Angela Hoye, Wissam Jaber, Farouc A Jaffer, Yangsoo Jang, Risto Jussila, Artis Kalnins, Arun Kalyanasundaram, David E Kandzari, Hsien-Li Kao, Dimitri Karmpaliotis, Hussien Heshmat Kassem, Jaikirshan Khatri, Paul Knaapen, Ran Kornowski, Oleg Krestyaninov, A V Ganesh Kumar, Pablo Manuel Lamelas, Seung-Whan Lee, Thierry Lefevre, Raymond Leung, Yu Li, Yue Li, Soo-Teik Lim, Sidney Lo, William Lombardi, Anbukarasi Maran, Margaret McEntegart, Jeffrey Moses, Muhammad Munawar, Andres Navarro, Hung M Ngo, William Nicholson, Anja Oksnes, Goran K Olivecrona, Lucio Padilla, Mitul Patel, Ashish Pershad, Marin Postu, Jie Qian, Alexandre Quadros, Nidal Abi Rafeh, Truls Råmunddal, Vithala Surya Prakasa Rao, Nicolaus Reifart, Robert F Riley, Stephane Rinfret, Meruzhan Saghatelyan, George Sianos, Elliot Smith, Anthony Spaedy, James Spratt, Gregg Stone, Julian W Strange, Khalid O Tammam, Craig A Thompson, Aurel Toma, Jennifer A Tremmel, Ricardo Santiago Trinidad, Imre Ungi, Minh Vo, Vu Hoang Vu, Simon Walsh, Gerald Werner, Jaroslaw Wojcik, Jason Wollmuth, Bo Xu, Masahisa Yamane, Luiz F Ybarra, Robert W Yeh, and Qi Zhang

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A Comparison of statistical methods for hospital performance assessment, Xiaoting Wu, Min Zhang, Ruyun Jin, Gary Grunkemeier, Charles Maynard, Ravi S. Hira, Todd Mackenzie, Morley Herbert, Chang He, Sari D. Holmes, Michael P. Thompson, and Donald S. Likosky

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Effects of radiation on tumor vasculature., Tomoko Yamazaki and Kristina H Young

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Cardiovascular Procedural Deferral and Outcomes over COVID-19 Pandemic Phases: A Multi-Center Study., Celina M Yong, Kateri J Spinelli, Shih Ting Chiu, Brandon Jones, Brian Penny, Santosh Gummidipundi, Shire Beach, Alex Perino, Mintu Turakhia, Paul Heidenreich, and Ty J Gluckman

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Equitable Evaluation Framework and Governance Recommendations, Marisa Zapata (Lead Researcher), L Bentley Moses, Sarah Mercurio, Ritu Ghosal, and Greg Townley

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Six months in: COVID-19 and its impact on oncology social work practice., Brad Zebrack, Michael Grignon, Ting Guan, Donna Long, Nina Miller, Krista Nelson, Shirley Otis-Green, Makeeta Rayton, Tara Schapmire, and Lori Wiener

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Phenotyping Cardiogenic Shock., Elric Zweck, Katherine L Thayer, Ole K L Helgestad, Manreet Kanwar, Mohyee Ayouty, A Reshad Garan, Jaime Hernandez-Montfort, Claudius Mahr, Detlef Wencker, Shashank S Sinha, Esther Vorovich, Jacob Abraham, William O'Neill, Song Li, Gavin W Hickey, Jakob Josiassen, Christian Hassager, Lisette O Jensen, Lene Holmvang, Henrik Schmidt, Hanne B Ravn, Jacob E Møller, Daniel Burkhoff, and Navin K Kapur

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Compatibility of novel cardiogenic shock phenotypes from the Cardiogenic Shock Working Group (CSWG) with the SCAI staging system, E Zweck, KL Thayer, OK Helgestad, M Kanwar, M Ayouty, A Garan, J Hernandez-Montfort, C Mahr, D Wencker, S Sinha, E Vorovich, Jacob Abraham, W O'Neill, S Li, GW Hickey, J Jossiasen, C Hassager, LO Jensen, L Holmvang, H Schmidt, HB Ravn, JE Moeller, D Burkhoff, and NK Kapur

Submissions from 2020

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Management of the Patient with Heart Failure and an Implantable Pulmonary Artery Hemodynamic Sensor, Jacob Abraham, Patrick J. McCann, Maya E. Guglin, Arvind Bhimaraj, Terrie-Ann S. Benjamin, Monique R. Robinson, Orvar T. Jonsson, Scott C. Feitell, Kunjan A. Bhatt, Mosi K. Bennett, JT Heywood, and Hemodynamic Frontiers in Heart Failure (HF2) Investigators

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Characterization of a Novel Compound That Stimulates STING-Mediated Innate Immune Activity in an Allele-Specific Manner., Jinu Abraham, Sara Botto, Nobuyo Mizuno, Kara Pryke, Bryan Gall, Dylan Boehm, Tina M Sali, Haihong Jin, Aaron Nilsen, Michael J. Gough, Jason R Baird, Marita Chakhtoura, Caroline Subra, Lydie Trautmann, Elias K Haddad, and Victor R DeFilippis

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Life experiences associated with change in perpetration of domestic violence., Avanti Adhia, Vivian H Lyons, Hannah Cohen-Cline, and Ali Rowhani-Rahbar

Dangerous liaisons in pulmonary hypertension, Sophia Airhart

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Phase II Trial of IL-12 Plasmid Transfection and PD-1 Blockade in Immunologically Quiescent Melanoma., Alain P Algazi, Christopher G Twitty, Katy K Tsai, Mai Le, Robert Pierce, Erica Browning, Reneta Hermiz, David A Canton, Donna Bannavong, Arielle Oglesby, Murray Francisco, Lawrence Fong, Mikael J Pittet, Sean P Arlauckas, Christopher Garris, Lauren P Levine, Carlo Bifulco, Carmen Ballesteros-Merino, Shailender Bhatia, Sharron Gargosky, Robert H I Andtbacka, Bernard A Fox, Michael D Rosenblum, and Adil I Daud

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Phase II Trial of IL-12 Plasmid Transfection and PD-1 Blockade in Immunologically Quiescent Melanoma., Alain P Algazi, Christopher G Twitty, Katy K Tsai, Mai Le, Robert Pierce, Erica Browning, Reneta Hermiz, David A Canton, Donna Bannavong, Arielle Oglesby, Murray Francisco, Lawrence Fong, Mikael J Pittet, Sean P Arlauckas, Christopher Garris, Lauren P Levine, Carlos Bifulco, Carmen Ballesteros-Merino, Shailender Bhatia, Sharron Gargosky, Robert H I Andtbacka, Bernard A Fox, Michael D Rosenblum, and Adil I Daud

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Transcarotid versus transthoracic access for transcatheter aortic valve replacement: A Propensity Matched Analysis, Keith B. Allen, Adnan K. Chhatriwalla, John Saxon, James Hermiller, David Heimansohn, Sina Moainie, Raymond G. McKay, Mohiuddin Cheema, Brandon Jones, Robert W. Hodson, Ethan C Korngold, and Eric B Kirker

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Intracellular Galectin-3 Is Essential for OX40-Mediated Memory CD8, Mohammad Farhad Amani, Annah S Rolig, and William L. Redmond

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Improving Care Pathways for Acute Coronary Syndrome: Patients Undergoing Percutaneous Coronary Intervention., Amit P Amin, John A Spertus, Hemant Kulkarni, Christian McNeely, Sunil V Rao, Duane Pinto, John A House, John C Messenger, Richard G Bach, Abhinav Goyal, Adhir Shroff, Samir Pancholy, Steven M Bradley, Tyler J Gluckman, Thomas M Maddox, Jason H Wasfy, and Frederick A Masoudi

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Sgnlva-005: Open-label, phase II study of ladiratuzumab vedotin (LV) for advanced aerodigestive tract malignancies, Ian Churchill Anderson, Yinghui Wang, Zejing Wang, and Rachel E Sanborn

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Sgnlva-005: Open-label, phase II study of ladiratuzumab vedotin (LV) for advanced aerodigestive tract malignancies., Ian Churchill Anderson, Yinghui Wang, Zejing Wang, and Rachel E Sanborn

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Safety and activity of varlilumab, a novel and first-in-class agonist anti-CD27 antibody, for hematologic malignancies., Stephen M Ansell, Ian Flinn, Matthew H Taylor, Branimir I Sikic, Joshua Brody, John Nemunaitis, Andrew Feldman, Thomas R Hawthorne, Tracey Rawls, Tibor Keler, and Michael J Yellin

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Phase II Trial of Carfilzomib Plus Irinotecan in Patients with Small Cell Lung Cancer Who Have Progressed on Prior Platinum-Based Chemotherapy., Susanne M. Arnold, Kari Chansky, Maria Q. Baggstrom, Michael A. Thompson, Rachel E Sanborn, John L. Villano, Saiama N. Wagar, John Hamm, Markos Leggas, Maurice Willis, Joseph Rosales, and John J. Crowley

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The Great Debate at 'Immunotherapy Bridge', Naples, December 5, 2019., Paolo A Ascierto, Carlo Bifulco, Jerome Galon, Claus Garbe, Samir N Khleif, Jennifer McQuade, Kunle Odunsi, Hideho Okada, Chrystal M Paulos, Sergio A Quezada, Hussein A Tawbi, John Timmerman, Giorgio Trinchieri, Lisa H Butterfield, and Igor Puzanov

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Insights from immuno-oncology: The Society for Immunotherapy of Cancer statement on access to IL-6-targeting therapies for COVID-19, Paolo A. Ascierto; Bernard A Fox; Walter Urba; Ana Carrizosa Anderson; Michael Atkins; Ernest C. Borden; Julie R. Brahmer; Lisa H. Butterfield; Alessandra Cesano; Daniel S. Chen; Tanja D. De Gruijl; Robert O. Dillman; Charles G. Drake; Leisha A. Emens; Thomas F. Gajewski; James L. Gulley; F Stephen Hodi, Jr.; Patrick Hwu; David Kaufman; Howard L. Kaufman; Michael T. Lotze; Francesco M. Marincola; Kim A. Margolin; Michael J. Mastrangelo; Marcela V. Maus; Douglas G. McNeel; David R. Parkinson; Pedro J. Romero; Paul M. Sondel; Stefani Spranger; Mario Sznol; George J. Weiner; Jon M. Wigginton; and Jeffrey S. Weber

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No time to die: the consensus immunoscore for predicting survival and response to chemotherapy of locally advanced colon cancer patients in a multicenter international study., Paolo A Ascierto, Francesco M Marincola, Bernard A Fox, and Jérôme Galon

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Perspectives in melanoma: meeting report from the "Melanoma Bridge" (December 5th-7th, 2019, Naples, Italy)., Paolo A Ascierto, Igor Puzanov, Sanjiv S Agarwala, Christian Blank, Richard D Carvajal, Sandra Demaria, Reinhard Dummer, Marc Ernstoff, Soldano Ferrone, Bernard A Fox, Thomas F Gajewski, Claus Garbe, Patrick Hwu, Roger S Lo, Georgina V Long, Jason J Luke, Iman Osman, Michael A Postow, Ryan J Sullivan, Janis M Taube, Giorgio Trinchieri, Hassane M Zarour, Corrado Caracò, and Magdalena Thurin

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Contemporary Techniques in Orbital Reconstruction: A Review of the Literature and Report of a Case Combining Surgical Navigation, Computer-Aided Surgical Simulation, and a Patient-Specific Implant., Iman Azarmehr, Kasper Stokbro, R Bryan Bell, and Torben Thygesen

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Outpatient treatment with lisocabtagene maraleucel (liso-cel) across a variety of clinical sites from three ongoing clinical studies in relapsed/refractory (R/R) large B-cell lymphoma (LBCL)., Carlos R. Bachier, John E Godwin, Charalambos Andreadis, Maria Lia Palomba, Jeremy S. Abramson, Alison R. Sehgal, Gerhard Hildebrandt, Don A. Stevens, Daanish Hoda, Edward J. Licitra, Tanya Siddiqi, Thalia Andrea Farazi, Ana Kostic, Nikolaus S. Trede, Lei Wang, James Lymp, and David G. Mahoney

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Outpatient Treatment with Lisocabtagene Maraleucel (liso-cel) in 3 Ongoing Clinical Studies in Relapsed/Refractory (R/R) Large B Cell Non-Hodgkin Lymphoma (NHL), Including Second-Line Transplant Noneligible (TNE) Patients: Transcend NHL 001, Outreach, and PILOT, Carlos R. Bachier, M Lia Palomba, Jeremy S. Abramson, Charalambos Andreadis, Alison Sehgal, John E Godwin, Gerhard C. Hildebrandt, Tanya Siddiqi, Don Stevens, Thalia Farazi, Ana Kostic, Nikolaus S. Trede, Lei Wang, James Lymp, Tennille Thelen, Ken Ogasawara, and David G. Maloney

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United States Pulmonary Hypertension Scientific Registry: Baseline Characteristics., Jessica B Badlam, David B Badesch, Eric D Austin, Raymond L Benza, Wendy K Chung, Harrison W Farber, Kathy Feldkircher, Adaani E Frost, Abby D Poms, Katie A Lutz, Michael W Pauciulo, Chang Yu, William C Nichols, C Gregory Elliott, additional authors, and Sophia Airhart

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ACCEL Lite: Case Rates, Treatment, and Outcomes in AMI During the COVID-19 Pandemic, Alison Bailey, Joseph Edward Marine, Tyler J Gluckman, and Yuvraj Chowdhury

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Improved tolerability of neratinib in patients with HER2-positive early-stage breast cancer: the CONTROL trial., C H Barcenas, S A Hurvitz, J A Di Palma, R Bose, A J Chien, N Iannotti, G Marx, A Brufsky, A Litvak, E Ibrahim, R H Alvarez, M Ruiz-Borrego, N Chan, Y Manalo, A Kellum, M Trudeau, M Thirlwell, J Garcia Saenz, D Hunt, R Bryce, L McCulloch, H S Rugo, D Tripathy, A Chan, CONTROL Study Investigators, and Alison Conlin

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Feature | Thrombosis and COVID-19: FAQs For Current Practice, Geoffrey D. Barnes, Adam Cuker, Tyler J Gluckman, Gregory Piazza, and Deborah M. Siegal

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What are thrombosis risk and management considerations in COVID-19?, Geoffrey D. Barnes, Adam Cuker, Tyler J Gluckman, Gregory Piazza, and Deborah M. Siegal

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Image processing systems and methods for displaying multiple images of a biological specimen, Michael Barnes, Carlo Bifulco, Christophe Chefd'hotel, Ting Chen, and Alisa Tubbs

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Image processing systems and methods for displaying multiple images of a biological specimen, Michael Barnes, Carlo Bifulco, Christophe Chefd'hotel, Ting Chen, and Alisa Tubbs

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Abstract B01: Surgical outcomes following neoadjuvant hypofractionated radiation in combination with nivolumab: High rate of pathologic complete response in patients with p16+ head and neck squamous cell carcinoma, Richard Bryan Bell, Rom Leidner, Marcus Couey, Ashish Patel, Amber L Watters, Hong Ziao, Carlo Bifulco, Brian D. Piening, George Morris, Lessli Rushforth, Dawn Brucker, Shorin Nemeth, Kristina H Young, Michael J. Gough, and Marka R Crittenden

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Abstract B01: Surgical outcomes following neoadjuvant hypofractionated radiation in combination with nivolumab: High rate of pathologic complete response in patients with p16+ head and neck squamous cell carcinoma, Richard Bryan Bell, Rom Leidner, Marcus Couey, Ashish Patel, Amber L Watters, Hong Ziao, Carlo Bifulco, Brian D. Piening, George Morris, Lessli Rushforth, Dawn Brucker, Shorin Nemeth, Kristina H Young, Michael J. Gough, and Marka R Crittenden

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Cohort Expansion Study of Neoadjvuant Immunoradiotherapy in Locoregionally Advanced HPV+ and HPV- Head and Neck Squamous Cell Carcinoma, Richard Bryan Bell, Rom Leidner, Kristina H Young, Brendan Curti, Marcus Couey, Ashish Patel, Amber L Watters, Hong D Xiao, George Morris, Lessli Rushforth, Michael J. Gough, and Marka R Crittenden

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Cohort Expansion Study of Neoadjvuant Immunoradiotherapy in Locoregionally Advanced HPV+ and HPV- Head and Neck Squamous Cell Carcinoma, Richard Bryan Bell, Rom Leidner, Kristina H Young, Brendan Curti, Marcus Couey, A Patel, Amber L Watters, Hong D Xiao, G Morris, L Rushforth, Michael J. Gough, and Marka R Crittenden