Submissions from 2020
Association of immunophenotype with expression of topoisomerase II α and β in adult acute myeloid leukemia., Andrew P Michelson, Shannon McDonough, Cheryl L Willman, Eric R Koegle, John E Godwin, Stephen H Petersdorf, Alan F List, Megan Othus, Frederick R Appelbaum, Jerald P Radich, Mahrukh K Ganapathi, Anjali S Advani, and Ram N Ganapathi
422 An open-label, multicenter, phase 1/2 clinical trial of RP1, an enhanced potency oncolytic HSV, combined with nivolumab: updated results from the skin cancer cohorts, Mark Middleton, Francesca Aroldi, Joseph Sacco, Mohammed Milhem, Brendan Curti, Ari VanderWalde MBioeth, Scott Baum, Adel Samson, Anna Pavlick, Jason Chesney, Jiaxin Niu, Terence Rhodes, Tawnya Bowles, Robert Conry, Anna Olsson-Brown, Douglas Earl Laux, Howard Kaufman, Praveen Bommareddy, Alex Deterding, Selda Samakoglu, Robert Coffin, and Kevin Harrington
422 An open-label, multicenter, phase 1/2 clinical trial of RP1, an enhanced potency oncolytic HSV, combined with nivolumab: updated results from the skin cancer cohorts, Mark Middleton, Francesca Aroldi, Joseph Sacco, Mohammed Milhem, Brendan Curti, Ari VanderWalder MBioeth, Scott Baum, Adel Samson, Anna Pavlick, Jason Chesney, Jiaxin Niu, Terence Rhodes, Tawnya Bowles, Robert Conry, Anna Olsson-Brown, Douglas Earl Laux, Howard Kaufman, Praveen Bommareddy, Alex Deterding, Selda Samakoglu, Robert Coffin, and Kevin Harrington
An open-label, single-arm, phase II clinical trial of RP1, an enhanced potency oncolytic herpes virus, combined with nivolumab in four solid tumor types: Initial results from the skin cancer cohorts., Mark R. Middleton, Francesca Aroldi, Joseph Sacco, Mohammed M. Milhem, Brendan Curti, Ari M. Vanderwalde, Scott Baum, Adel Samson, Anna C. Pavlick, Jason Alan Chesney, Jiaxin Niu, Terence Duane Rhodes, Tawnya Lynn Bowles, Anna Olsson-Brown, Douglas Earl Laux, Praveen Bommareddy, Alex Deterding, Joseph Elassal, Robert S. Coffin, and Kevin Harrington
Multicenter International Society for Immunotherapy of Cancer Study of the Consensus Immunoscore for the Prediction of Survival and Response to Chemotherapy in Stage III Colon Cancer., Bernhard Mlecnik, Carlo Bifulco, Gabriela Bindea, Florence Marliot, Alessandro Lugli, J Jack Lee, Inti Zlobec, Tilman T Rau, Martin D Berger, Iris D Nagtegaal, Elisa Vink-Börger, Arndt Hartmann, Carol Geppert, Julie Kolwelter, Susanne Merkel, Robert Grützmann, Marc Van den Eynde, Anne Jouret-Mourin, Alex Kartheuser, Daniel Léonard, Christophe Remue, Julia Y Wang, Prashant Bavi, Michael H A Roehrl, Pamela S Ohashi, Linh T Nguyen, SeongJun Han, Heather L MacGregor, Sara Hafezi-Bakhtiari, Bradly G Wouters, Giuseppe V Masucci, Emilia K Andersson, Eva Zavadova, Michal Vocka, Jan Spacek, Lubos Petruzelka, Bohuslav Konopasek, Pavel Dundr, Helena Skalova, Kristyna Nemejcova, Gerardo Botti, Fabiana Tatangelo, Paolo Delrio, Gennaro Ciliberto, Michele Maio, Luigi Laghi, Fabio Grizzi, Tessa Fredriksen, Bénédicte Buttard, Lucie Lafontaine, Daniela Bruni, Anastasia Lanzi, Carine El Sissy, Nacilla Haicheur, Amos Kirilovsky, Anne Berger, Christine Lagorce, Christopher Paustian, Carmen Ballesteros-Merino, Jeroen Dijkstra, Carlijn van de Water, Shannon van Lent-van Vliet, Nikki Knijn, Ana-Maria Muşină, Dragos-Viorel Scripcariu, Boryana Popivanova, Mingli Xu, Tomonobu Fujita, Shoichi Hazama, Nobuaki Suzuki, Hiroaki Nagano, Kiyotaka Okuno, Toshihiko Torigoe, Noriyuki Sato, Tomohisa Furuhata, Ichiro Takemasa, Kyogo Itoh, Prabhu S Patel, Hemangini H Vora, Birva Shah, Jayendrakumar B Patel, Kruti N Rajvik, Shashank J Pandya, Shilin N Shukla, Yili Wang, Guanjun Zhang, Yutaka Kawakami, Francesco M Marincola, Paolo A Ascierto, Bernard A Fox, Franck Pagès, and Jérôme Galon
Effects of Radiation on the Tumor Microenvironment., Arta M Monjazeb, Kurt A Schalper, Franz Villarroel-Espindola, Anthony Nguyen, Stephen L Shiao, and Kristina H Young
Effects of Radiation on the Tumor Microenvironment., Arta M Monjazeb, Kurt A Schalper, Franz Villarroel-Espindola, Anthony Nguyen, Stephen L Shiao, and Kristina H Young
Tumor antigen expression and survival of patients with previously treated advanced non-small cell lung cancer (NSCLC) receiving viagenpumatucel-L (HS-110) plus nivolumab., Daniel Morgensztern, Saiama Naheed Waqar, Lyudmila Bazhenova, Lori McDermott, Jeff Hutchins, David H. Taylor, Fred L. Robinson, Alexa K Dowdell, Brian D. Piening, Wael A. Harb, Nathan A. Pennell, and Roger B. Cohen
QP 15 - Biology 07 - Radiation and Immunotherapy, Zachary Scott Morris and Kristina H Young
Effects of YOCAS yoga, cognitive behavioral therapy, and survivorship health education on insomnia: A URCC NCORP Research Base Phase III RCT in 740 cancer survivors., Karen Michelle Mustian, Po-Ju Lin, Eva Culakova, Javier Bautista, Huiwen Xu, Supriya Gupta Mohile, Michelle Christine Janelsins, Luke Joseph Peppone, Amber Kleckner, Ian Kleckner, Kah Poh Loh, Richard Francis Dunne, Nikesha Gilmore, Alison Conlin, Kim Ong Gococo, and Anthony John Jaslowski
A first-in-human phase 1 dose escalation study of spartalizumab (PDR001), an anti-PD-1 antibody, in patients with advanced solid tumors., Aung Naing, Justin F Gainor, Hans Gelderblom, Patrick M Forde, Marcus O Butler, Chia-Chi Lin, Sunil Sharma, Maria Ochoa de Olza, Andrea Varga, Matthew H Taylor, Jan H M Schellens, Hongqian Wu, Haiying Sun, Antonio P Silva, Jason Faris, Jennifer Mataraza, Scott Cameron, and Todd M Bauer
The Impact of Local Heart Allocation on Post-Transplant Survival, Vidang P. Nguyen and T Dardas
Chapter: Primary Care of the Adult Heart Transplant Recipient, Vidang P. Nguyen, Andy Y. Lee, and Richard K. Cheng
Chapter: Ventricular Assist Device as Bridge-to-Transplant, Vidang P. Nguyen and Song Li
Atezolizumab Plus Chemotherapy for First-Line Treatment of Non-Squamous Non-Small Cell Lung Cancer: Results From the Randomized Phase III IMpower132 Trial., Makoto Nishio, Fabrice Barlesi, Howard West, Simon Ball, Rodolfo Bordoni, Manuel Cobo, Pascale Dubray Longeras, Jerome Goldschmidt, Silvia Novello, Francisco Orlandi, Rachel E Sanborn, Zsuzsanna Szalai, Grigoriy Ursol, Diana Mendus, Lijia Wang, Xiaohui Wen, Mark McCleland, Tien Hoang, See Phan, and Mark A Socinski
375O Final efficacy results from IMpower132: First-line atezolizumab + chemotherapy in patients with stage IV non-squamous NSCLC, M Nishio, F Barlesi, S Ball, R Bordoni, M Cobo, P Dubray-Longeras, J Goldschmidt, S Novello, FJ Orlandi, Rachel E Sanborn, Z Szalai, G Ursol, D Mendus, L Wang, X Wen, M McCleland, T Hoang, S Phan, and M Socinski
375O - Final efficacy results from IMpower132: First-line atezolizumab + chemotherapy in patients with stage IV non-squamous NSCLC, M Nishio (presenter), F Barlesi, S Ball, R Bordoni, M Cobo, P Dubray-Longeras, J Goldschmidt, S Novello, FJ Orlandi, Rachel E Sanborn, Z Szalai, G Ursol, D Mendus, L Wang, X Wen, M McCleland, T Hoang, S Phan, and M Socinski
Management of adverse events in patients with HER2+ metastatic breast cancer treated with tucatinib, trastuzumab, and capecitabine (HER2CLIMB)., Alicia Frances Claire Okines, Elisavet Paplomata, Tanya Wahl, Gail Lynn Shaw Wright, Stephanie Sutherland, Erik Jakobsen, Frances Valdes, Arlene Chan, Amy Sanders Clark, Alison Conlin, Maryam B. Lustberg, Jennifer M. Specht, Timothy J. Pluard, Xiaofu Zhu, Ian E. Krop, Karen A. Gelmon, Dennis J. Slamon, Jorge Ramos, Grace An, and Erika Paige Hamilton
Coronavirus Disease 2019 (COVID-19): Epidemiology, Clinical Spectrum and Implications for the Cardiovascular Clinician, Ohad Oren, Stephen L. Kopecky, Tyler J Gluckman, Bernard J. Gersh, and Roger S. Blumenthal
The Use of Chloroquine and Hydroxychloroquine in COVID-19 and Cardiovascular Implications: Understanding Safety Discrepancies to Improve Interpretation and Design of Clinical Trials., Ohad Oren, Eric H Yang, Tyler J Gluckman, Erin D Michos, Roger S Blumenthal, and Bernard J Gersh
Response to radiotherapy in pancreatic ductal adenocarcinoma is enhanced by inhibition of myeloid-derived suppressor cells using STAT3 anti-sense oligonucleotide., Ayman J Oweida, Adam C Mueller, Miles Piper, Dallin Milner, Benjamin Van Court, Shilpa Bhatia, Andy Phan, Thomas Bickett, Kimberly Jordan, Theresa Proia, Richard Schulick, Wells A Messersmith, Marco Del Chiaro, Eric Clambey, Michael J. Gough, Jason Williams, Kirk Hansen, Karyn Goodman, and Sana D Karam
The NEALS primary lateral sclerosis registry., Sabrina Paganoni, Fabiola De Marchi, James Chan, Sara K Thrower, Nathan P Staff, Neil Datta, Yaz Y Kisanuki, Vivian Drory, Christina Fournier, Erik P Pioro, Stephen A Goutman, Nazem Atassi, NEALS PLS Registry Study Group, Maryangel Jeon, Sarah Caldwell, Timothy Mcdonough, Caroline Gentile, Jianing Liu, Michelle Turner, Carol Denny, Kevin Felice, Misty Green, Stephanie Scarberry, Saad Abu-Saleh, Beatrice Nefussy, Debbie Hastings, Sangri Kim, Blake Swihart, Ximena Arcila-Londono, Daniel S Newman, Michael Silverman, Angela Genge, Kristiana Salmon, Lauren Elman, Leo Mccluskey, Kelly Almasy, Marc Gotkine, Kimberly Goslin, Arlena Cummings, Eli K Edwards, Michael Rivner, Kristy Bouchard, Brandy Quarles, Justin Kwan, Matthew Jaffa, Robert Baloh, Peggy Allred, David Walk, Samuel Maiser, Georgios Manousakis, Valerie Ferment, J Americo M Fernandes, Pariwat Thaisetthawatkul, Deborah Heimes, Melissa Phillips, Laura Sams, Melissa Kahler, Alecia Corcoran, Daniel G Larriviere, Sadie Chotto, and Gracy Juba
Intermediate-Term Left Ventricular Function Following Non-Emergent Impella Protected PCI: Restore EF Study, Mitul Patel, Jason R Wollmuth, Thom Dahle, Craig Thompson, Ehtisham Mahmud, and D. Lynn Morris
Progesterone receptor membrane component 1 promotes the growth of breast cancers by altering the phosphoproteome and augmenting EGFR/PI3K/AKT signalling., Diego A Pedroza, Venkatesh Rajamanickam, Ramadevi Subramani, Alejandra Bencomo, Adriana Galvez, and Rajkumar Lakshmanaswamy
Neoantigen-specific CD4(+) T-cell response is critical for the therapeutic efficacy of cryo-thermal therapy, Peng Peng, Hong-Ming Hu, Ping Liu, and Lisa X Xu
Advanced symposium peripheral arterial disease: controversies in treatment, Alejandro Perez
Hyperbaric medicine hyperbaric oxygen therapy: monoplace chamber, Alejandro Perez
Peripheral artery disease: basic principles for the wound care clinician, Alejandro Perez
Updates in Venous Disease Management, Alejandro Perez
Vascular testing, know why provider wants testing, Alejandro Perez
Quality review and education as method of improving guideline adherence for medication prescription and outcomes among vascular interventionalists performing non-cardiac vascular surgeries, Alejandro Perez, Shih-Ting Chiu, A Manning, and Brant W Ullery
Obesity Drives Delayed Infarct Expansion, Inflammation, and Distinct Gene Networks in a Mouse Stroke Model., Todd C Peterson, Kendra J Lechtenberg, Brian D. Piening, Tawaun A Lucas, Eric Wei, Hassan Chaib, Alexa K Dowdell, Michael Snyder, and Marion S Buckwalter
Enabling Scalable Comprehensive Genomic Profiling from FFPE Samples, Brian D. Piening
Comprehensive Genomic Profiling in Patients with Advanced Cancer in a Large US Healthcare System, Brian D. Piening, Alexa K Dowdell, Roshanthi Weerasinghe, B Bapat, R Roe, Nancy Biery, Shwetha Pindikuri, Sheila Reynolds, David Ball, Mary Campbell, Thomas R. Ward, A Stein, B Schroeder, H Poon, D Eberhard, and Carlo Bifulco
Ageotypes: Distinct Biomolecular Trajectories in Human Aging., Brian D. Piening, Jennifer Lovejoy, and John C Earls
AML risk stratification models utilizing ELN-2017 guidelines and additional prognostic factors: a SWOG report., Era L Pogosova-Agadjanyan, Anna Moseley, Megan Othus, Frederick R Appelbaum, Thomas R Chauncey, I-Ming L Chen, Harry P Erba, John E Godwin, Isaac C Jenkins, Min Fang, Mike Huynh, Kenneth J Kopecky, Alan F List, Jasmine Naru, Jerald P Radich, Emily Stevens, Brooke E Willborg, Cheryl L Willman, Brent L Wood, Qing Zhang, Soheil Meshinchi, and Derek L Stirewalt
Comprehensive Immune Profiling of Medullary Thyroid Cancer., Nikita Pozdeyev, Timothy A Erickson, Lian Zhang, Kim Ellison, Christopher J Rivard, Sharon Sams, Fred R Hirsch, Bryan R Haugen, and Jena D French
Nivolumab Monotherapy and Nivolumab Plus Ipilimumab in Recurrent Small Cell Lung Cancer: Results From the CheckMate 032 Randomized Cohort., Neal E Ready, Patrick A Ott, Matthew D Hellmann, Jon Zugazagoitia, Christine L Hann, Filippo de Braud, Scott J Antonia, Paolo A Ascierto, Victor Moreno, Akin Atmaca, Stefania Salvagni, Matthew H Taylor, Asim Amin, D Ross Camidge, Leora Horn, Emiliano Calvo, Ang Li, Wen Hong Lin, Margaret K Callahan, and David R Spigel
Confirmatory Tissue Sampling in Clinical Stage I Sarcoidosis., Jerome M Reich
Screening for COPD., Jerome M Reich
Response to Grannis FW. Current Controversies in Cardiothoracic Imaging: Overdiagnosis at Lung Cancer Screening-No So Bad After All-Counterpoint., Jerome M Reich and Jong S Kim
Using nitrous acid-modified de Man, Rogosa, and Sharpe medium to selectively isolate and culture lactic acid bacteria from dairy foods., Matthew A Renschler, Asia Wyatt, Nnamdi Anene, Rona Robinson-Hill, Ethan S Pickerill, Nathaniel E Fox, Julie A Griffith, and John L McKillip
Manual Scalp Cooling in Early Stage Breast Cancer: Value of Caretaker Training and Patient-Reported Experience to Optimize Efficacy and Patient Selection, Manaz Rezayee, Nikki Moxon, Staci Mellinger, Amanda Y Seino, Nicole E. Fredich, Tracy L. Kelly, Susan Mulligan, Patrick Rossi, Ijeoma Uche, Walter Urba, Alison Conlin, Janet Ruzich, and David B Page
Comparison of Echocardiographic Outcomes Following Transcatheter Aortic Valve Replacement With Edwards S3 23 MM Versus Medtronic Evolut 26 MM Valves, Michael Ring, Ruyun Jin, Rollie Parrish, Brydan Curtis, Matthew Forrester, Branden Reynolds, and Sameer Gafoor
Comparison of echocardiographic outcomes following transcatheter aortic valve replacement with Edwards S3 23mm versus Medtronic Evolut 26mm valves, Michael Ring, Ruyun Jin, Rollie Parrish, Brydan Curtis, Matthew Forrester, Branden Reynolds, and Sameer Gafoor
Racial and Ethnic Differences in Presentation and Outcomes for Patients Hospitalized with COVID-19: Findings from the American Heart Association's COVID-19 Cardiovascular Disease Registry., Fatima Rodriguez, Nicole Solomon, James A de Lemos, Sandeep R Das, David A Morrow, Steven M Bradley, Mitchell S V Elkind, Joseph H Williams Iv, DaJuanicia Holmes, Roland A Matsouaka, Divya Gupta, Tyler J Gluckman, Marwah Abdalla, Michelle A Albert, Clyde W Yancy, and Tracy Y Wang
451 Combining Bempegaldesleukin (CD122-preferential IL-2 pathway agonist) and NKTR-262 (TLR7/8 agonist) pairs local innate activation with systemic CD8+ T cell expansion to enhance anti-tumor immunity, Annah S Rolig, Daniel Rose, Saul Kivimae, Werner Rubas, and William L. Redmond
451 Combining Bempegaldesleukin (CD122-preferential IL-2 pathway agonist) and NKTR-262 (TLR7/8 agonist) pairs local innate activation with systemic CD8+ T cell expansion to enhance anti-tumor immunity, Annah S Rolig, Daniel Rose, Saul Kivimae, Werner Rubas, and William L. Redmond
Clinical Characteristics of Patients Classified as Very High Risk and Not Very High Risk Based on the 2018 AHA/ACC Multi-Society Cholesterol Guideline, Aparna Sajja, Amir Ali, Hsin-Fang Li, Kateri Spinelli, Salim S. Virani, Seth Shay Martin, and Tyler J Gluckman
405 CDX1140–01, a phase 1 dose-escalation/expansion study of CDX-1140 alone (Part 1) and in combination with CDX-301 (Part 2) or pembrolizumab (Part 3), Rachel E Sanborn, Ralph Hauke, Nashat Gabrail, Mark O'Hara, Nina Bhardwaj, Rodolfo Bordoni, Michael Gordon, Danny Khalil, Maen Abdelrahim, Thomas Marron, Thomas Hawthorne, Lawrence Thomas, Tracey Rawls, Diego Alavardo, Laura Vitale, Tibor Keler, and Michael Yellin
405 CDX1140–01, a phase 1 dose-escalation/expansion study of CDX-1140 alone (Part 1) and in combination with CDX-301 (Part 2) or pembrolizumab (Part 3), Rachel E Sanborn, Ralph Hauke, Nashat Gabrail, Mark O'Hara, Nina Bhardwaj, Rodolfo Bordoni, Michael Gordon, Danny Khalil, Maen Abdelrahim, Thomas Marron, Thomas Hawthorne, Lawrence Thomas, Tracey Rawls, Mark Rogalski, Diego Alvarado, Laura Vitale, Tibor Keler, and Michael Yellin
Concordance of multispectral immunofluorescence (mIF) with programmed death ligand 1 (PD-L1) and stromal tumor infiltrating lymphocyte (sTILs) clinical assays in early-stage breast cancer (BC)., Katherine Sanchez, Shu-Ching Chang, Isaac Kim, Maritza Martel, Yaping Wu, William L. Redmond, Zhaoyu Sun, Dottie Waddell, Deborah R. Laxague, Brady Bernard, Monil Shah, Walter Urba, and David B. Page
Human-engineered Treg-like cells suppress FOXP3-deficient T cells but preserve adaptive immune responses, Yohei Sato, Laura Passerini, Brian D. Piening, Molly Javier Uyeda, Marianne Goodwin, Silvia Gregori, Michael P Snyder, Alice Bertaina, Maria-Grazia Roncarolo, and Rosa Bacchetta
Lisocabtagene maraleucel (liso-cel) for treatment of second-line (2L) transplant noneligible (TNE) relapsed/refractory (R/R) aggressive large B-cell non-Hodgkin lymphoma (NHL): Updated results from the PILOT study., Alison R. Sehgal, Gerhard Hildebrandt, Nilanjan Ghosh, John E Godwin, Nina D. Wagner-Johnston, Daanish Hoda, Edward J. Licitra, Javier Munoz, Nikolaus S. Trede, Lei Wang, Jerill Thorpe, and Leo I. Gordon
Interim subgroup analysis for response by PD-L1 status of CLASSICAL-Lung, a phase Ib/II study of pepinemab (VX15/2503) in combination with avelumab in advanced NSCLC., Michael Rahman Shafique, Terrence Lee Fisher, Elizabeth E. Evans, John E. Leonard, Desa Rae Electa Pastore, Crystal L. Mallow, Ernest Smith, Andreas Schroder, Kevin M. Chin, Joseph Thaddeus Beck, Megan Ann Baumgart, Ramaswamy Govindan, Nashat Y. Gabrail, Rachel E Sanborn, Alexander I. Spira, Nagashree Seetharamu, Yanyan Lou, Aaron Scott Mansfield, Jonathan Wade Goldman, and Maurice Zauderer
Interim results from a phase Ib/II study of pepinemab in combination with avelumab in advanced NSCLC patients following progression on prior systemic and/or anti-PDx therapies., Michael Rahman Shafique, Terrence Lee Fisher, Elizabeth E. Evans, John E. Leonard, Desa Rae Electa Pastore, Crystal L. Mallow, Ernest Smith, Andreas Schroder, Kevin M. Chin, J Thaddeus Beck, Megan Ann Baumgart, Ramaswamy Govindan, Nashat Y. Gabrail, Rachel E Sanborn, Alexander I. Spira, Nagashree Seetharamu, Yan Yan Lou, Aaron Scott Mansfield, Jonathan Wade Goldman, and Maurice Zauderer
1020O A phase I, first-in-human, open-label, dose escalation study of MGD019, an investigational bispecific PD-1 x CTLA-4 DART® molecule in patients with advanced solid tumours, M Sharma, Rachel E Sanborn, GM Cote, JC Bendell, S Kaul, F Chen, A Berezhnoy, P Moore, E Bonvini, BJ Sumrow, and JJ Luke
Lower Rates of Heart Failure and All-Cause Hospitalizations During Pulmonary Artery Pressure-Guided Therapy for Ambulatory Heart Failure: One-Year Outcomes From the CardioMEMS Post-Approval Study., David M Shavelle, Akshay S Desai, William T Abraham, Robert C Bourge, Nirav Raval, Lisa D Rathman, J Thomas Heywood, Rita A Jermyn, Jamie Pelzel, Orvar T Jonsson, Maria Rosa Costanzo, John D Henderson, Marie-Elena Brett, Philip B Adamson, Lynne W Stevenson, CardioMEMS Post-Approval Study Investigators, and Jacob Abraham (CardioMEMS Post-Approval Study Investigator)
407 Preliminary safety, pharmacokinetics/pharmacodynamics, and antitumor activity of XmAb20717, a PD-1 x CTLA-4 bispecific antibody, in patients with advanced solid tumors, Elaine Shum, Adil Daud, Matthew Reilley, Yana Najjar, John Thompson, Joaquina Baranda, R Donald Harvey, Rom Leidner, Anthony Shields, Ezra Cohen, Roger Cohen, Alain Mita, Shubham Pant, Mark Stein, Bartosz Chmielowski, Siwen Hu-Lieskovan, Catherine Fleener, Ying Ding, Sowmya Chollate, Hector Avina, Jolene Shorr, Raphael Clynes, and Barbara Hickingbottom
407 Preliminary safety, pharmacokinetics/pharmacodynamics, and antitumor activity of XmAb20717, a PD-1 x CTLA-4 bispecific antibody, in patients with advanced solid tumors, Elaine Shum, Adil Daud, Matthew Reilley, Yana Najjar, John Thompson, Joaquina Baranda, R Donald Harvey, Rom Leidner, Anthony Shields, Ezra Cohen, Alain Mita, Shubham Pant, Mark Stein, Bartosz Chmielowski, Siwen Hu-Lieskovan, Catherine Fleener, Ying Ding, Sowmya Chollate, Hector Avina, Jolene Shorr, Raphael Clynes, and Barbara Hickingbottom
The Role of Hemodynamic Support in High-risk Percutaneous Coronary Intervention, Charles Simonton, Craig Thompson, Jason R Wollmuth, D Lynn Morris, and Thom G. Dahle
Effect of various decontamination procedures on disposable N95 mask integrity and SARS-CoV-2 infectivity, Jeffrey Smith, Haley Hanseler, John Welle, Rogan Rattray, Mary Campbell, Tacy Brotherton, Tarsem Moudgil, Thomas F. Pack, Keith W Wegman, Shawn M. Jensen, Justin Jin, Carlo Bifulco, Scott A. Prahl, Bernard A Fox, and Nicholas L Stucky
Effect of various decontamination procedures on disposable N95 mask integrity and SARS-CoV-2 infectivity., Jeffrey S Smith, Haley Hanseler, John Welle, Rogan Rattray, Mary Campbell, Tacy Brotherton, Tarsem Moudgil, Thomas F Pack, Keith Wegmann, Shawn Jensen, Justin Jin, Carlo B Bifulco, Scott A Prahl, Bernard A Fox, and Nicholas L Stucky
What is the Cost-Effective Treatment for Melanoma Patients with a Positive Sentinel Node?, Hayley Standage, Alyssa R Hersh, Aaron Caughey, Matthew H Taylor, John Vetto, and Dale Han
Breaking the Mold: Designing Health Plans That Do Not Impede Delivery of High-Value Care., Eric C Stecker, Lonny Reisman, Larry A Allen, and Tyler J Gluckman
Response to anti-PD-1 and anti-LAG-3 immune checkpoint blockade (ICB) is associated with induction of pro-inflammatory Tregs, Elizabeth Sturgill, Courtney Mick, Johanna K. Kaufmann, and William L. Redmond
Clinical activity of the RET inhibitor pralsetinib (BLU-667) in patients with RET fusion+ solid tumors., Vivek Subbiah, Mini I-Nan Hu, Justin F. Gainor, Aaron Scott Mansfield, Guzman Alonso, Matthew H Taylor, Viola Weijia Zhu, Pilar Garrido Lopez, Alessio Amatu, Robert C. Doebele, Philippe Alexandre Cassier, Bhumsuk Keam, Martin H. Schuler, Hui Zhang, Corinne Clifford, Michael Palmer, Jennifer Green, Christopher D. Turner, and Giuseppe Curigliano
560 Alpha-tocopheryloxyacetic acid induces apoptosis of murine rhabdomyosarcoma in vitro while modulating innate and adaptive immune responses in vivo, Fernanda Szewc, Longzhen Song, Sean Rinella, Christopher Dubay, Emmanuel Akporiaye, William L. Redmond, and Christian Capitini
560 Alpha-tocopheryloxyacetic acid induces apoptosis of murine rhabdomyosarcoma in vitro while modulating innate and adaptive immune responses in vivo, Fernanda Szewc, Longzhen Song, Sean Rinella, Christopher Dubay, Emmanuel Akporiaye, William L. Redmond, and Christian Capitini
The Society for Immunotherapy of Cancer statement on best practices for multiplex immunohistochemistry (IHC) and immunofluorescence (IF) staining and validation., Janis M Taube, Guray Akturk, Michael Angelo, Elizabeth L Engle, Sacha Gnjatic, Shirley Greenbaum, Noah F Greenwald, Cyrus V Hedvat, Travis J Hollmann, Jonathan Juco, Edwin R Parra, Marlon C Rebelatto, David L Rimm, Jaime Rodriguez-Canales, Kurt A Schalper, Edward C Stack, Cláudia S Ferreira, Konstanty Korski, Ana Lako, Scott J Rodig, Emanuel Schenck, Keith E Steele, Michael J Surace, Michael T Tetzlaff, Katharina von Loga, Ignacio I Wistuba, Carlo Bifulco, and Society for Immunotherapy of Cancer (SITC) Pathology Task Force.
A mutation-specific, single-arm, phase 2 study of dovitinib in patients with advanced malignancies., Matthew H Taylor, Ajjai S Alva, Timothy Larson, Sebastian Szpakowski, Das Purkaystha, Alpesh Amin, Linda Karpiak, and Sarina A Piha-Paul
The LEAP program: lenvatinib plus pembrolizumab for the treatment of advanced solid tumors., Matthew H Taylor, Emmett V Schmidt, Corina Dutcus, Elaine M Pinheiro, Yasuhiro Funahashi, Gregory Lubiniecki, and Drew Rasco
Loss of switch/sucrose non-fermenting complex protein expression in undifferentiated gastrointestinal and pancreatic carcinomas., Basile Tessier-Cloutier, David F Schaeffer, Julinor Bacani, Celia E Marginean, Steve Kalloger, Martin Köbel, and Cheng-Han Lee
172 Increasing activation of human tumor-reactive T cells (CD39+CD103+CD8+) by gene silencing of PD1 with self-delivering RNAi INTASYL(TM), Colin Thalhofer, Ryan Montler, Melissa Maxwell, Dingxue Yan, James Cardia, Simon Fricker, Jacob Moses, Joshua Rios, Tarsem Moudgil, Bernard A Fox, Nick Morris, Richard Bryan Bell, and Andrew Weinberg
172 Increasing activation of human tumor-reactive T cells (CD39+CD103+CD8+) by gene silencing of PD1 with self-delivering RNAi INTASYL(TM), Colin Thalhofer, Ryan Montler, Melissa Maxwell, Dingxue Yan, James Cardia, Simon Fricker, Jacob Moses, Joshua Rios, Tarsem Moudgil, Bernard A Fox, Nick Morris, Richard Bryan Bell, and Andrew D Weinberg
Invasive Hemodynamic Assessment and Classification of In-Hospital Mortality Risk Among Patients With Cardiogenic Shock., Katherine L Thayer, Elric Zweck, Mohyee Ayouty, A Reshad Garan, Jaime Hernandez-Montfort, Claudius Mahr, Kevin J Morine, Sarah Newman, Lena Jorde, Jillian L Haywood, Neil M Harwani, Michele L Esposito, Carlos D Davila, Detlef Wencker, Shashank S Sinha, Esther Vorovich, Jacob Abraham, William O'Neill, James Udelson, Daniel Burkhoff, and Navin K Kapur
PROCLAIM-CX-072: Analysis of patients with advanced solid tumors receiving long-term treatment with CX-072, a PD-L1 probody therapeutic, as a single agent or in combination with ipilimumab., Fiona Thistlethwaite, Aung Naing, Marta Gil-Martin, Patricia LoRusso, Manreet Randhawa, Ferry Eskens, Rachel E Sanborn, Nataliya Volodymyrivna Uboha, Daniel C. Cho, Alexander I. Spira, Igor Bondarenko, Elizabeth Ruth Plummer, Javier Garcia-Corbacho, Ivan Victoria, Javier Lavernia, Ignacio Melero, Elisabeth De Vries, William Garner, Hendrik-Tobias Arkenau, and Johanna C. Bendell
Urelumab alone or in combination with rituximab in patients with relapsed or refractory B-cell lymphoma., John Timmerman, Charles Herbaux, Vincent Ribrag, Andrew D Zelenetz, Roch Houot, Sattva S Neelapu, Theodore Logan, Izidore S Lossos, Walter Urba, Gilles Salles, Radhakrishnan Ramchandren, Caron Jacobson, John Godwin, Cecilia Carpio, Deanne Lathers, Yali Liu, Jaclyn Neely, Satyendra Suryawanshi, Yoshinobu Koguchi, and Ronald Levy
2020 ACC Expert Consensus Decision Pathway on Management of Bleeding in Patients on Oral Anticoagulants: A Report of the American College of Cardiology Solution Set Oversight Committee., Gordon F Tomaselli, Kenneth W Mahaffey, Adam Cuker, Paul P Dobesh, John U Doherty, John W Eikelboom, Roberta Florido, Tyler J Gluckman, William J Hucker, Roxana Mehran, Steven R Messé, Alexander C Perino, Fatima Rodriguez, Ravindra Sarode, Deborah M Siegal, and Barbara S Wiggins
Targeting MerTK Enhances Adaptive Immune Responses After Radiation Therapy., Garth W Tormoen, Tiffany C Blair, Shelly Bambina, Gwen Kramer, Jason Baird, Ramtin Rahmani, John M Holland, Owen J T McCarty, Michael J Baine, Vivek Verma, Nima Nabavizadeh, Michael J Gough, and Marka Crittenden
op Goals and Concerns Reported by Individuals with Inflammatory Bower Disease at Outpatient Gastroenterology Clinic Visits, Chang Sang Tse, Samir Shah, Damara Crate, Ridhima Oberai, Caroline Hwang, Arthur Ostrov, Donald Lum, Eugene Nelson, Brant Oliver, Aricca Van Citters, Megan Holthoff, Alice Kennedy, Jason Hou, Siddharth Signh, Alandra Weaver, Gil Melmed, Corey Siegel, and Welmoed van Deen
PD-1 and PD-L1 Inhibitors: A Single Center Medication Assistance Program (MAP) Experience, Sarah Tu and Shuntao Cai
Device selection in TEVAR, Brant Ullery
Grand Rounds: Spinal protection strategies in contemporary aortic surgery, Brant Ullery
Management of abdominal aortic aneurysms with hostile infrarenal necks, Brant Ullery
Nearly 30 years of EVAR: Contemporary insights on long-term durability, Brant Ullery
Peripheral artery disease: Patient treatment, selection and device options in vascular surgery, Brant Ullery
Practical tools as healthcare emerges from the pandemic, Brant Ullery
Role of TEVAR in acute aortic syndromes, Brant Ullery
Supporting ruptured abdominal aortic aneurysm cases, Brant Ullery
Technical challenges in the treatment of ruptured AAAs. How to salvage the opportunity for ruptured EVAR, Brant Ullery
TEVAR in the fragile aorta, Brant Ullery
Prophylactic Ruxolitinib for Cytokine Release Syndrome in Relapse/Refractory AML Patients Treated with Flotetuzumab., Geoffrey L. Uy, Michael P. Rettig, Stephanie Christ, Ibrahim Aldoss, Michael T. Byrne, Harry P. Erba, Martha L. Arellano, Matthew C. Foster, John E Godwin, Farhad Ravandi, Peter H. Sayre, Anjali S. Advani, Matthew J. Wieduwilt, Ashkan Emadi, Laura C. Michaelis, Patrick J. Stiff, Martin Wermke, Norbert Vey, Patrice Chevalier, Emmanuel Gyan, Christian Recher, Fabio Ciceri, Matteo Giovanni Carrabba, Antonio Curti, Geert Huls, Max S. Topp, Mojca Jongen-Lavrencic, John Muth, Teia Curtis, Mary Beth Collins, Erin Timmeny, Kuo Guo, Jian Zhao, Kathy Tran, Patrick Kaminker, Priyanka Patel, Ouiam Bakkacha, Kenneth Jacobs, Maya Kostova, Jennifer Seiler, Bob Lowenberg, Sergio Rutella, Roland B. Walter, Ezio Bonvini, Jan K. Davidson-Moncada, and John F. DiPersio
TP53 abnormalities correlate with immune infiltration and associate with response to flotetuzumab immunotherapy in AML., Jayakumar Vadakekolathu, Catherine Lai, Stephen Reeder, Sarah E Church, Tressa Hood, Anbarasu Lourdusamy, Michael P Rettig, Ibrahim Aldoss, Anjali S Advani, John E Godwin, Matthew J Wieduwilt, Martha Arellano, John Muth, Tung On Yau, Farhad Ravandi, Kendra Sweet, Heidi Altmann, Gemma A Foulds, Friedrich Stölzel, Jan Moritz Middeke, Marilena Ciciarello, Antonio Curti, Peter J M Valk, Bob Löwenberg, Ivana Gojo, Martin Bornhäuser, John F DiPersio, Jan K Davidson-Moncada, and Sergio Rutella
TP53 abnormalities correlate with immune infiltration and associate with response to flotetuzumab immunotherapy in AML., Jayakumar Vadakekolathu, Catherine Lai, Stephen Reeder, Sarah E Church, Tressa Hood, Anbarasu Lourdusamy, Michael P Rettig, Ibrahim Aldoss, Anjali S Advani, John E Godwin, Matthew J Wieduwilt, Martha Arellano, John Muth, Tung On Yau, Farhad Ravandi, Kendra Sweet, Heidi Altmann, Gemma A Foulds, Friedrich Stölzel, Jan Moritz Middeke, Marilena Ciciarello, Antonio Curti, Peter J M Valk, Bob Löwenberg, Ivana Gojo, Martin Bornhäuser, John F DiPersio, Jan K Davidson-Moncada, and Sergio Rutella
Immune Senescence and Exhaustion Correlate with Response to Flotetuzumab, an Investigational CD123×CD3 Bispecific Dart® Molecule, in Acute Myeloid Leukemia, Jayakumar Vadakekolathu, Tung On Yau, Sarah E. Church, Michael P. Rettig, Ibarhim Aldoss, Geoffrey L. Uy, Norbert Vey, Ashkan Emadi, Peter H. Sayre, Roland B. Walter, Matthew C. Foster, Martha L. Arellano, John E Godwin, Matthew J. Wieduwilt, Michael T. Byrne, Laura C. Michaelis, Patrick J. Stiff, Matteo Giovanni Carrabba, Patrice Chevalier, Emmanuel Gyan, Christian Recher, Anjali S. Advani, Martin Wermke, Harry P. Erba, Fabio Ciceri, Geert Huls, Mojca Jongen-Lavrencic, Farhad Ravandi, Antonio Curti, Max S. Topp, John Muth, Patrick Kaminker, Bob Lowenberg, Ivana Gojo, Leo Luznik, John F. DiPersio, Jan K. Davidson-Moncada, and Sergio Rutella
Global impact of the first coronavirus disease 2019 (COVID-19) pandemic wave on vascular services., Vascular and Endovascular Research Network (VERN) COVER study collaborative and Brant Ullery (Vascular and Endovascular Research Network (VERN) COVER study collaborative)
Transoral robotic surgery and neck dissection for HPV-positive oropharyngeal carcinoma: Importance of nodal count in survival., Chi T Viet, Eric J Dierks, Allen C Cheng, Ashish Patel, Shu-Ching Chang, Marcus Couey, Amber L Watters, Thien Hoang, Hong D Xiao, Marka R Crittenden, Rom Leidner, Steven K Seung, Kristina H Young, and Richard Bryan Bell
NKTR-214 immunotherapy synergizes with radiotherapy to stimulate systemic CD8, Joshua M Walker, Annah S Rolig, Deborah H Charych, Ute Hoch, Melissa Kasiewicz, Daniel Rose, Michael J McNamara, Ian F Hilgart-Martiszus, and William L. Redmond
A multicenter trial of a shared DECision Support Intervention for Patients offered implantable Cardioverter-DEfibrillators: DECIDE-ICD rationale, design, Medicare changes, and pilot data., Bryan C Wallace, Larry A Allen, Christopher E Knoepke, Russell E Glasgow, Carmen L Lewis, Diane L Fairclough, Laura J Helmkamp, Monica D Fitzgerald, Wendy S Tzou, Daniel B Kramer, Paul D Varosy, Sanjaya K Gupta, John M Mandrola, Scott Brancato, Pamela N Peterson, and Daniel D Matlock
