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Submissions from 2020

Intersection of antiplatelets and anticoagulants—What to do when a patient needs both?, Tyler J Gluckman

Late-breaking clinical trials III, Tyler J Gluckman

Leveraging technology for quality improvement—what would Alexa and Siri say?, Tyler J Gluckman

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New Payment Model for E/M Services: Benefits and Risks of One Level of Service, Tyler J Gluckman

Non-communicable Diseases and the Toll it has Taken, Tyler J Gluckman

Quality of care, appropriate utilization criteria, the ACC-NCDR and professional code of ethics, Tyler J Gluckman

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Remote Patient Monitoring to Help with Cardiovascular Prevention During the COVID-19 Pandemic, Tyler J Gluckman

We have a service line: now what?, Tyler J Gluckman

We started. Now we need to implement (and get paid for) these subspecialty clinics, Tyler J Gluckman

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Managing Chronic Disease During COVID-19: Views From the US and Europe, Tyler J Gluckman, Katie Berlacher, and Simon G. Ray

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Trends in Diagnosis Related Groups for Inpatient Admissions and Associated Changes in Payment From 2012 to 2016., Tyler J Gluckman, Kateri Spinelli, Mansen Wang, Amir Yazdani, Gary Grunkemeier, Steven M Bradley, Jason H Wasfy, Abhinav Goyal, Andrew Oseran, and Karen E Joynt Maddox

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How can remote patient monitoring help with cardiovascular prevention during COVID-19?, Tyler J Gluckman and Pam Taub

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What is home-based cardiac rehabilitation and how could it be used during COVID-19?, Tyler J Gluckman and Pam Taub

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What telehealth strategies are available to address stress, anxiety, physical inactivity, suboptimal nutrition and ongoing tobacco use in patients with cardiovascular disease?, Tyler J Gluckman and Pam Taub

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Differential Use and Impact of Bleeding Avoidance Strategies on Percutaneous Coronary Intervention-Related Bleeding Stratified by Predicted Risk., Tyler J Gluckman, L Wang, Kateri Spinelli, John Petersen, Paul P Huang, Amit Amin, John C Messenger, and Sunil V Rao

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Case Rates, Treatment Approaches, and Outcomes in Acute Myocardial Infarction During the Coronavirus Disease 2019 Pandemic, Tyler J Gluckman, Michael Wilson, Shih-Ting Chiu, Brian Penny, Vinaya Chepuri, John Waggoner, and Kateri Spinelli

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Race, Ethnicity, & Social Determinants in COVID-19: An Expert Panel Discussion, Tyler J Gluckman, Clyde W. Yancy, and Shrilla Banerjee

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Outcomes of Treatment with the Chimeric Antigen Receptor (CAR) T Cell Therapy Lisocabtagene Maraleucel (liso-cel) in the Nonuniversity Setting: Initial Results from the Outreach Study, John E Godwin, Cesar O. Freytes, Michael Maris, Don A. Stevens, Daanish Hoda, Bassam Mattar, Juan C. Varela, Mohamad Cherry, James Essell, Jay Courtright, Suzanne R. Fanning, Habte A. Yimer, Nikolaus S. Trede, Marina Youssef, James Lymp, and Carlos Bachier

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Safety and tolerability of MEDI0562 in combination with durvalumab or tremelimumab in patients with advanced solid tumors., Jonathan Wade Goldman, Sarina Anne Piha-Paul, Brendan Curti, Katrina Pedersen, Todd Michael Bauer, Stefanie L. Groenland, Richard D. Carvajal, Vaishali Chhaya, Scott A. Hammond, Katie Streicher, Danielle Michelle Townsley, Young Kwang Chae, Jens Voortman, Aurelien Marabelle, and John D. Powderly

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Safety and tolerability of MEDI0562 in combination with durvalumab or tremelimumab in patients with advanced solid tumors., Jonathan Wade Goldman, Sarina Anne Piha-Paul, Brendan Curti, Katrina Pedersen, Todd Michael Bauer, Stefanie L. Groenland, Richard D. Carvajal, Vaishali Chhaya, Scott A. Hammond, Katie Streicher, Danielle Michelle Townsley, Young Kwang Chae, Jens Voortman, Aurelien Marabelle, and John D. Powderly

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CT191 - Interim results from CLASSICAL-Lung, phase 1b/2 study of pepinemab (VX15/2503) in combination with avelumab in advanced NSCLC, Jonathan W. Goldman, Terrence L. Fisher, Elizabeth Evans, John E. Leonard, Desa Rae Pastore, Crystal Mallow, Ernest Smith, Andreas Schroder, Kevin Chin, Michael Shafique, Thaddeus Beck, Megan A. Baumgart, Ramaswamy Govindan, Nashat Gabrail, Rachel E Sanborn, Alexander Spira, Nagashree Seetharamu, Yanyan Lou, Aaron S. Mansfield, and Maurice Zauderer

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Abstract CT191: Interim results from CLASSICAL-Lung, phase 1b/2 study of pepinemab (VX15/2503) in combination with avelumab in advanced NSCLC, Jonathan W. Goldman, Terrence L. Fisher, Elizabeth Evans, John E. Leonard, Desa Rae Pastore, Crystal Mallow, Ernest Smith, Andreas Schroeder, Kevin Chin, Michael Shafique, Thaddeaus Beck, Megan A. Baumgart, Ramaswamy Govindan, Nashat Gabrail, Rachel E Sanborn, Alexander I. Spira, Nagashree Seetharamu, Yanyan Lou, Aaron S. Mansfield, and Maurice Zauderer

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Using Preclinical Data to Design Combination Clinical Trials of Radiation Therapy and Immunotherapy., Michael J. Gough, Shay Sharon, Marka R Crittenden, and Kristina H Young

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Using Preclinical Data to Design Combination Clinical Trials of Radiation Therapy and Immunotherapy., Michael J. Gough, Shay Sharon, Marka R Crittenden, and Kristina H Young

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A phase II single-arm study of pembrolizumab with enzalutamide in men with metastatic castration-resistant prostate cancer progressing on enzalutamide alone., Julie N Graff, Tomasz M Beer, Joshi J Alumkal, Rachel E Slottke, William L. Redmond, George V Thomas, Reid F Thompson, Mary A Wood, Yoshinobu Koguchi, Yiyi Chen, Emile Latour, Raymond C Bergan, Charles G Drake, and Amy E Moran

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Conserved Interferon-γ Signaling Drives Clinical Response to Immune Checkpoint Blockade Therapy in Melanoma., Catherine S Grasso, Jennifer Tsoi, Mykola Onyshchenko, Gabriel Abril-Rodriguez, Petra Ross-Macdonald, Megan Wind-Rotolo, Ameya Champhekar, Egmidio Medina, Davis Y Torrejon, Daniel Sanghoon Shin, Phuong Tran, Yeon Joo Kim, Cristina Puig-Saus, Katie Campbell, Agustin Vega-Crespo, Michael Quist, Christophe Martignier, Jason J Luke, Jedd D Wolchok, Douglas B Johnson, Bartosz Chmielowski, F Stephen Hodi, Shailender Bhatia, William Sharfman, Walter Urba, Craig L Slingluff, Adi Diab, John B A G Haanen, Salvador Martin Algarra, Drew M Pardoll, Valsamo Anagnostou, Suzanne L Topalian, Victor E Velculescu, Daniel E Speiser, Anusha Kalbasi, and Antoni Ribas

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The effect of increased cost-sharing on low-value service use., Jonathan Gruber, Johanna Catherine Maclean, Bill J. Wright, Eric Wilkinson, and Kevin G Volpp

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Invited Commentary. Mitral valve replacement with a third-generation porcine valve: an Italian multicenter study, Gary Grunkemeier

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Germinal centers in tertiary lymphoid structures distinguish long-term pancreatic cancer survivors associated with neoantigen expression and immune memory, Andrew J Gunderson

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TGFβ suppresses CD8+ T cell expression of CXCR3 and tumor trafficking., Andrew J Gunderson, Tomoko Yamazaki, Kayla McCarty, Nathaniel E Fox, Michaela Phillips, Alejandro F Alice, Tiffany Blair, Mark Whiteford, David O'Brien, Rehan Ahmad, Maria X Kiely, Amanda Hayman, Todd Crocenzi, Michael J. Gough, Marka R. Crittenden, and Kristina H Young

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Initial and Consolidation Therapy for Younger Patients with Mantle Cell Lymphoma., Daniel Guy and Brad S Kahl

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Results of Lung Cancer Screening in the Community., John R Handy, Michael Skokan, Erika Rauch, Steven Zinck, Rachel E Sanborn, Svetlana Kotova, and Mansen Wang

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Results of Lung Cancer Screening in the Community., John R Handy, Michael Skokan, Erika Rauch, Steven Zinck, Rachel E Sanborn, Svetlana Kotova, and Mansen Wang

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Three-Dimensional Computer-Assisted Surgical Planning, Manufacturing, and Intraoperative Navigation in Oncologic Surgery., Phillip Harrison, Ashish Patel, Allen C Cheng, and Richard Bryan Bell

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Simultaneously spatial and temporal Higher-Order Total Variations for noise suppression and motion reduction in DCE and IVIM., Renjie He, Yao Ding, Abdallah S R Mohamed, Sweet Ping Ng, Rachel B Ger, Hesham Elhalawani, Baher A Elgohari, Kristina H Young, Katherine A Hutcheson, Clifton D Fuller, and Stephen Y Lai

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Allogeneic autophagosome-enriched composition for the treatment of disease, Traci Hilton, Sandra Aung, Rieneke van de Ven, Christopher Paustian, Tarsem Moudgil, Christopher Dubay, Christopher Twitty, Hong-Ming Hu, and Bernard A Fox

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Allogeneic autophagosome-enriched composition for the treatment of disease, Traci Hilton, Sandra Aung, Rieneke van de Ven, Christopher Paustian, Tarsem Moudgil, Christopher Dubay, Christopher Twitty, Hong-Ming Hu, and Bernard A Fox

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Allogeneic autophagosome-enriched composition for the treatment of disease, Traci Hilton, Sandra Aung, Rieneke van de Ven, Christopher Paustian, Tarsem Moudgil, Christopher Dubay, Christopher Twitty, Hong-Ming Hu, and Bernard A Fox

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Allogeneic autophagosome-enriched composition for the treatment of disease, Traci Hilton, Sandra Aung, Rieneke van de Ven, Christopher Paustian, Tarsem Moudgil, Christopher Dubay, Christopher Twitty, Hong-Ming Hu, and Bernard A Fox

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Transcriptomic Profiling of Human Effector and Regulatory T Cell Subsets Identifies Predictive Population Signatures., Barbara Höllbacher, Thomas Duhen, Samantha Motley, Maria M Klicznik, Iris K Gratz, and Daniel J Campbell

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Finding a Path to Inspiration, Xiaoyan Huang

Practicing Cardiology in Portland 2020: Amidst Covid, Protests and Fire, Xiaoyan Huang

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SITC cancer immunotherapy resource document: a compass in the land of biomarker discovery., Siwen Hu-Lieskovan, Srabani Bhaumik, Kavita Dhodapkar, Jean-Charles J B Grivel, Sumati Gupta, Brent A Hanks, Sylvia Janetzki, Thomas O Kleen, Yoshinobu Koguchi, Amanda W Lund, Cristina Maccalli, Yolanda D Mahnke, Ruslan D Novosiadly, Senthamil R Selvan, Tasha Sims, Yingdong Zhao, and Holden T Maecker

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Cumulative suppressive index as a predictor of relapse free survival and overall survival in Human Papilloma Virus-negative oral squamous cell carcinomas with negative resection margins., Lauren Hum, Daniel Bethmann, Zipei Feng, Shu-Ching Chang, Alexander Eckert, Carmen Ballesteros-Merino, Claudia Keschke, Matthias Kappler, Carlo Bifulco, Claudia Wickenhauser, Barbara Seliger, Bernard A Fox, and Richard Bryan Bell

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Early fortification of enteral feedings for infants <1250 grams birth weight receiving a human milk diet including human milk based>fortifier., Robert Huston, Martin Lee, Evelyn Rider, Melissa Stawarz, Dawn Hedstrom, Melissa Pence, Vera Chan, Jessica Chambers, Stefanie Rogers, Nadine Sager, Laurie Riemann, and Howard Cohen

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Early cost-utility analysis of tissue-engineered heart valves compared to bioprostheses in the aortic position in elderly patients., Simone A Huygens, Isaac Corro Ramos, Carlijn V C Bouten, Jolanda Kluin, Shih Ting Chiu, Gary Grunkemeier, Johanna J M Takkenberg, and Maureen P M H Rutten-van Mölken

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Development and Pilot Testing of the Inflammatory Bowel Disease Nutrition Care Pathway., Caroline Hwang, Kelly Issokson, Catherine Giguere-Rich, Swapna Reddy, Andrew Tinsley, Welmoed K Van Deen, Harry Bray, Donald Lum, Humberto Aguilar, Timothy L Zisman, Ziad Younes, Damara Crate, Ridhima Oberai, Alandra Weaver, Gil Melmed, Corey Siegel, and Jason K Hou

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Examining the Impact of the 2019 Novel Coronavirus and Pandemic-Related Hardship on Adverse Pregnancy and Infant Outcomes: Design and Launch of the HOPE COVID-19 Study, Laura L. Jelliffe-Pawlowski, Scott P. Oltman, Larry Rand, Karen A. Scott, Miriam Kuppermann, Rebecca Baer, April Bell, Gretchen Bandoli, Jean Costello, Nadia Diamond-Smith, Elissa Epel, Rebecca Jackson, Fei Jiang, Deborah A. Karasek, Christina Lindan, Allison O'Leary, Jeffrey Olgin, Matt Pantell, Alison Paquette, Nisha Parikh, Noah Peyser, Xianhua Piao, Aric Prather, George Rutherford, Kelli K. Ryckman, Martina Steurer-Muller, Jodi Stookey, Ganapati Srinivasa, Hollis Wright, Charles E. McCulloch, Brian D. Piening, Elizabeth E. Rogers, and Christina Chambers

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480 Preliminary evaluation of a novel coronavirus vaccine (CORVax) using electroporation of plasmid DNA encoding a stabilized prefusion SARS-CoV-2 spike protein alone or with transfection of plasmid IL-12, Shawn M. Jensen, Christopher Twitty, Christopher Paustian, Madelein Laws, Glenna McDonnell, Keith W Wegman, Tarsem Moudgil, Michael E Afentoulis, Mia Han, Kellie Malloy Foerter, David Canton, Jack Lee, Bianca Nguyen, John Rodriguez, Kim Jaffe, Brian D. Piening, Carlo Bifulco, Daniel O'Connor, Walter Urba, Rom Leidner, Traci Hilton, Hong-Ming Hu, and Bernard A Fox

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480 Preliminary evaluation of a novel coronavirus vaccine (CORVax) using electroporation of plasmid DNA encoding a stabilized prefusion SARS-CoV-2 spike protein alone or with transfection of plasmid IL-12, Shawn M. Jensen, Christopher Twitty, Christopher Paustian, Madelein Laws, Glenna McDonnell, Keith W Wegmann, Tarsem Moudgil, Michael E Afentoulis, Mia Han, Kellie Malloy Foerter, David Canton, Jack Lee, Biance Nguyen, John Rodriguez, Kim Jaffe, Brian D. Piening, Carlo Bifulco, Daniel O'Connor, Walter Urba, Rom Leidner, Traci Hilton, Hong-Ming Hu, and Bernard A Fox

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CX-2029, a PROBODY drug conjugate targeting CD71 (transferrin receptor): Results from a first-in-human study (PROCLAIM-CX-2029) in patients (Pts) with advanced cancer., Melissa Lynne Johnson, Anthony B. El-Khoueiry, Navid Hafez, Nehal J. Lakhani, Hirva Mamdani, Jordi Rodon Ahnert, Rachel E Sanborn, Thang Ho, Rachel Li, Jana Waldes, and Alexander I. Spira

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Implementation of a Cardiogenic Shock Protocol and Data Review Process is Associated With Improved In-Hospital Survival, Adrienne Jones, Renee Swanson, Kateri Spinelli, Joshua Remick, Daniel Westerdahl, Jill M Gelow, David Hotchkin, Jason Wells, Tim Lewis, Robert Kim, Jeff Robinson, Roxanna Barr, Sarah Ramelli, and Jacob Abraham

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Rapid ventricular pacing during transcatheter valve procedures using an internal device and programmer: A demonstration of feasibility., BM Jones, Yash Jobanputra, Amar Krishnaswamy, Stephanie Mick, Mandeep Bhargava, Bruce L Wilkoff, and Samir R Kapadia

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Nivolumab in Advanced Hepatocellular Carcinoma: Safety Profile and Select Treatment-Related Adverse Events From the CheckMate 040 Study., Karen Julien, Hiu Tung Leung, Carmen Fuertes, Megumi Mori, Miao-Jen Wang, Jocelyn Teo, Lisa Weiss, Sara Hamilton, Holly DiFebo, Yoon Jin Noh, Aralee Galway, Jane Koh, Edith Brutcher, Huanyu Zhao, Yun Shen, Marina Tschaika, and Yue-Yun To

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The Impact of Laser Use on the Outcomes of Balloon Uncrossable and Balloon Undilatable Chronic Total Occlusion Percutaneous Coronary Intervention, Judit Karacsonyi, Khaldoon Alaswad, James Choi, Jaikirshan Khatri, Farouc Amin Jaffer, Paul Poomipanit, Farshad Forouzandeh, Michalis Koutouzis, Ioannis Tsiafoutis, Mitul Patel, Ehtisham Mahmud, Oleg Krestyaninov, Brian Jefferson, Taral Patel, Alpesh Shah, Raj Chadwaney, Jason R Wollmuth, Abdul Sheikh, Robert Yeh, Hector Tamez, Wissam Jaber, Habib Samady, Bilal Milak, Srinivasa Potluri, Barry Uretsky, Anthony Doing, Philip Dattilo, Basem Elbarouni, Michael Love, Evangelia Vemmou, Ilias Nikolakopoulos, Iosif Xenogiannis, Bavana Rangan, Santiago Garcia, Imre Ungi, Ahmed ElGuindy, Omer Goktekin, Nidal Abi Rafeh, and Emmanouli Brilakis

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Facebook Live: Case rates, treatment approaches, and outcomes in heart patients during COVID-19, Laurie Kelly and Tyler J Gluckman

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Noninvasive biomarkers for prediction and diagnosis of heart transplantation rejection., Yeraz Khachatoorian, Vahe Khachadourian, Eleanor Chang, Erick R Sernas, Elaine F Reed, Mario Deng, Brian D. Piening, Alexandre C Pereira, Brendan Keating, and Martin Cadeiras

Continuity of care and outpatient management for patients with and at high risk for cardiovascular disease during the COVID-19 pandemic: A scientific statement from the American Society for Preventive Cardiology., Amit Khera, Seth J Baum, Tyler J Gluckman, Martha Gulati, Seth S Martin, Erin D Michos, Ann Marie Navar, Pam R Taub, Peter P Toth, Salim S Virani, Nathan D Wong, and Michael D Shapiro

Transcarotid Versus Subclavian/Axillary Access for Transcatheter Aortic Valve Replacement: A Propensity-Matched Analysis of Real World Data, Eric B Kirker

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Transcarotid vs Subclavian/Axillary Access for Transcatheter Aortic Valve Replacement with SAPIEN 3., Eric B Kirker, Ethan C Korngold, Robert W. Hodson, BM Jones, Raymond McKay, Mohiuddin Cheema, David Heimansohn, Sina Moainie, James Hermiller, Adnan Chatriwalla, John Saxon, and Keith B Allen

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Inflammatory and clinical risk factors for chemotherapy-induced peripheral neuropathy (CIPN): A nationwide longitudinal study in 143 cancer patients during chemotherapy., Ian Kleckner, Todd Jusko, Eva Culakova, Amber Kleckner, Matthew Asare, Julia Ellen Inglis, Kah Poh Loh, Luke Joseph Peppone, Jeffrey L. Berenberg, Alison Conlin, Deborah J. Ossip, and Karen Michelle Mustian

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760 Trough levels of ipilimumab in serum as a potential predictive biomarker of clinical outcomes for patients with advanced melanoma after treatment with ipilimumab, Yoshinobu Koguchi, Noriko Iwamoto, Takashi Shimada, Shu-Ching Chang, John Cha, Brian D. Piening, Brendan Curti, Walter Urba, and William L. Redmond

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760 Trough levels of ipilimumab in serum as a potential predictive biomarker of clinical outcomes for patients with advanced melanoma after treatment with ipilimumab, Yoshinobu Koguchi, Noriko Iwamoto, Takashi Shimada, Shu-Ching Chang, John Cha, Brian D. Piening, Brian Piening, Brendan Curti, Walter Urba, and William L. Redmond

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Patient and Physician Predictors of FFR/iFR Utilization in ACS and SIHD, Payal Kohli, Peiqi Wang, Andrew Wang, Lucy Liu, Ali Weinstein, Jeptha P. Curtis, John A. Spertus, Jonathan P. Piccini, Marty Makary, and Tyler J Gluckman

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Adoption of a Strategy of Cerebral Embolic Protection During Transcatheter Aortic Valve Replacement is Associated with Fewer Neurologic Events in a Large Volume Center, EC Korngold, EB Kirker, Robert W. Hodson, Ruyun Jin, Kateri Spinelli, Shih-Ting Chiu, S Verburg, V Kumar, and BM Jones

Adoption of a Strategy of Cerebral Embolic Protection During Transcatheter Aortic Valve Replacement is Associated with Fewer Neurologic Events in a Large Volume Center, Ethan C Korngold

Intravascular Lithotripsy for Peripheral Artery Disease and Vascular Access, Ethan C Korngold

Strategies for Aorto-Iliac CTO Crossing, Ethan C Korngold

Transcarotid TAVR: The best alternative, Ethan C Korngold

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Outcomes of Acute Myocardial Infarction Hospitalizations During the COVID-19 Pandemic, Margaret Krasne, Tyler J Gluckman, Joseph Edward Marine, Roger S. Blumenthal, and Garima Sharma

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Reply to Barner and Bruno-Murtha., Ravina Kullar, Jerod Nagel, Susan C Bleasdale, Sarah H Sutton, Snezana Naumovski, Cheryl Smith, James E Leggett, Dana Wollins, Chris Busky, and Ellie J C Goldstein

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2020 ACC Expert Consensus Decision Pathway for Anticoagulant and Antiplatelet Therapy in Patients With Atrial Fibrillation or Venous Thromboembolism Undergoing Percutaneous Coronary Intervention or With Atherosclerotic Cardiovascular Disease: A Report of the American College of Cardiology Solution Set Oversight Committee, Dharam J. Kumbhani, Christopher P. Cannon, Craig J. Beavers, Deepak L. Bhatt, Adam Cuker, Tyler J Gluckman, Joseph E. Marine, Roxana Mehran, Steven R. Messe, Nimesh S. Patel, Benjamin E. Peterson, Kenneth Rosenfield, Sarah A. Spinler, and Vinod H. Thourani

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Guidance for Cardiac Electrophysiology During the Coronavirus (COVID-19) Pandemic from the Heart Rhythm Society COVID-19 Task Force; Electrophysiology Section of the American College of Cardiology; and the Electrocardiography and Arrhythmias Committee of the Council on Clinical Cardiology, American Heart Association., Dhanunjaya R Lakkireddy, Mina K Chung, Rakesh Gopinathannair, Kristen K Patton, Tyler J Gluckman, Mohit Turagam, Jim Cheung, Parin Patel, Jaun Sotomonte, Rachel Lampert, Janet K Han, Bharath Rajagopalan, Lee Eckhardt, Jose Joglar, Kristin Sandau, Brian Olshansky, Elaine Wan, Peter A Noseworthy, Miguel Leal, Elizabeth Kaufman, Alejandra Gutierrez, Joseph M Marine, Paul J Wang, and Andrea M Russo

Coronary Atherosclerosis & Cardiovascular Risk Factors in Subjects with Clonal Hematopoiesis, Michael Layoun

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386 Phase I/Ib first-in-human study of HEK-NIZ985, a recombinant IL-15/IL-15Rα heterodimer, alone and in combination with spartalizumab, in adults with advanced and metastatic solid tumors, Rom Leidner, Andrea Wang-Gillam, Sumati Gupta, Robert Wesolowski, Douglas McNeel, Kevin Conlon, Nehal Parikh, Jessica O'Keeffe, Niladri Roy Chowdhury, Xiaoli Wang, Ryan Sullivan, and John Thompson

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386 Phase I/Ib first-in-human study of HEK-NIZ985, a recombinant IL-15/IL-15Rα heterodimer, alone and in combination with spartalizumab, in adults with advanced and metastatic solid tumors, Rom Leidner, Andrea Wang-Gillam, Sumati Gupta, Robert Wesolowski, Douglas McNeel, Kevin Conlon, Nehal Parikh, Jessica O'Keeffe, Niladri Roy Chowdhury, Xiaoli Wang, Ryan Sullivan, and John Thompson

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Metabolic Dynamics and Prediction of Gestational Age and Time to Delivery in Pregnant Women., Liang Liang, Marie-Louise Hee Rasmussen, Brian D. Piening, Xiaotao Shen, Songjie Chen, Hannes Röst, John K Snyder, Robert Tibshirani, Line Skotte, Norman Cy Lee, Kévin Contrepois, Bjarke Feenstra, Hanyah Zackriah, Michael Snyder, and Mads Melbye

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Abstract 219: Use of Machine Learning Models to Identify Atherosclerotic Cardiovascular Disease Patients at Very High Risk for Future Events in a Multi-state Health Care System, Hsin-Fang Li, Amir Ali, Kateri Spinelli, A Sajja, SS Virani, SS Martin, and Tyler J Gluckman

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CT301 - A phase Ib study to evaluate RO7198457, an individualized Neoantigen Specific immunoTherapy (iNeST), in combination with atezolizumab in patients with locally advanced or metastatic solid tumors, Juanita S. Lopez, Ross Camidge, Marco Iafolla, Sylvie Rottey, Martin Schuler, Matthew Hellmann, Ali Balmanoukian, Luc Dirix, Michael Gordon, Ryan Sullivan, Brian S. Henick, Charles Drake, Kit Wong, Patricia LoRusso, Patrick Ott, Lawrence Fong, Aglaia Schiza, Jeffrey Yachnin, Christian Ottensmeier, Fadi Braiteh, Johanna Bendell, Rom Leidner, George Fisher, Guy Jerusalem, Laura Molenaar-Kuijsten, Marcus Schmidt, Scott A. Laurie, Raid Aljumaily, Achim Rittmeyer, Eelke Gort, Ignacio Melero, Lars Mueller, Rachel Sabado, Patrick Twomey, Jack Huang, Manesh Yadav, Jingbin Zhang, Felicitas Mueller, Evelyna Derhovanessian, Ugur Sahin, Ozlem Tureci, and Thomas Powles

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Abstract CT301: A phase Ib study to evaluate RO7198457, an individualized Neoantigen Specific immunoTherapy (iNeST), in combination with atezolizumab in patients with locally advanced or metastatic solid tumors, Juanita S. Lopez, Ross Camidge, Marco Iafolla, Sylvie Rottey, Martin Schuler, Matthew Hellmann, Ani Balmanoukian, Luc Dirix, Michael Gordon, Ryan Sullivan, Bryan S. Henick, Chares Drake, Kit Wong, Patricia LoRusso, Patrick Ott, Lawrence Fong, Aglaia Schiza, Jeffrey Yachnin, Christian Ottensmeier, Fadi Braiteh, Joanna Bendell, Rom Leidner, George Fisher, Guy Jerusalem, Laura Molenaar-Kuijsten, Marcus Schmidt, Scott A. Laurie, Raid Aljumaily, Achim Rittmeyer, Eelke Gort, Ignacio Melero, Lars Mueller, Rachel Sabado, Patrick Twomey, Jack Huang, Manesh Yadav, Jingbin Zhang, Felicitas Mueller, Evelyna Derhovanessian, Ugur Sahin, Ozlem Tureci, and Thomas Powels

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154 Marrow-infiltrating lymphocytes (MILs): A novel adoptive immunotherapy for hematological and solid tumors, Eric Lutz, Lakshmi Rudraraju, Elizabeth DeOliveira, Amanda Seiz, Monil Shah, Celine Colmenares, Beverly Dan Fu, Daniela Bota, Collin Brummel, Chad Brenner, Paul Swiecicki, Nicole E. Fredich, David B Page, Eleni Efstatihiou, Ivan Borrello, and Kimberly Noonan

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154 Marrow-infiltrating lymphocytes (MILs): A novel adoptive immunotherapy for hematological and solid tumors, Eric Lutz, Lakshmi Rudraraju, Elizabeth DeOliveira, Amanda Seiz, Monil Shah, Celine Colmenares, Beverly Dan Fu, Daniela Bota, Collin Brummel, Chad Brenner, Paul Swiecicki, Nicole E. Fredich, David B Page, Eleni Efstatihiou, Ivan Borrello, and Kimberly Noonan

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COVID-19 Clinical Guidance For the Cardiovascular Care Team, Thomas M. Maddox, Eric C. Stecker, Biykem Bozkurt, Nathalie DeMichelis, John U. Doherty, Andrew Freeman, Tyler J Gluckman, Dipti Itchhaporia, Andrew P. Miller, Andrea L. Price, Lonny Reisman, Prem Soman, Mohammad Madjid, Scott D. Solomon, and Orly Vardeny

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Lenvatinib (LEN) plus pembrolizumab (PEMBRO) for early-line treatment of advanced/recurrent endometrial cancer (EC)., Vicky Makker, Matthew H Taylor, Carol Aghajanian, Ana Oaknin, James Mier, Allen Lee Cohn, Margarita Romeo, Raquel Bratos, Marcia S. Brose, Christopher DiSimone, Mark Messing, Lea Dutta, Min Ren, Emmett V. Schmidt, Robert Orlowski, Jodi Alicia McKenzie, Kathryn Gillis, and Antonio Casado Herraez

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Lenvatinib Plus Pembrolizumab in Patients With Advanced Endometrial Cancer., Vicky Makker, Matthew H Taylor, Carol Aghajanian, Ana Oaknin, James Mier, Allen L Cohn, Margarita Romeo, Raquel Bratos, Marcia S Brose, Christopher DiSimone, Mark Messing, Daniel E Stepan, Corina E Dutcus, Jane Wu, Emmett V Schmidt, Robert Orlowski, Pallavi Sachdev, Robert Shumaker, and Antonio Casado Herraez

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PD47-04 SINGLE CELL RNA-SEQUENCING OF FRESH SUPERFICIAL NON-MUSCLE INVASIVE BLADDER CANCER DEMONSTRATES GENE EXPRESSSION PATHWAY DIFFFERENCES BETWEEN HIGH AND LOW GRADE TUMORS, Stanley Malkowiicz, Brian D. Piening, Alexa Dowdell, David Walls, Nik Nair, Baoli Chang, and Brendan Keating

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A phase I/II study of rovalpituzumab tesirine in delta-like 3-expressing, advanced solid tumors., Aaron Scott Mansfield, David S. Hong, Christine L. Hann, Anna F. Farago, Himisha Beltran, Saiama Naheed Waqar, Andrew Eugene Hendifar, Lowell Brian Anthony, Matthew H Taylor, Alan Haruo Bryce, Scott T. Tagawa, Karl D. Lewis, Jiaxin Niu, Christine H. Chung, James M. Cleary, Michael Rossi, Carrianne Ludwig, Ricardo Valenzuela, Yan Luo, and Rahul Raj Aggarwal

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Exclusive Breastfeeding Rates at 6 Weeks Postpartum as a Function of Preconception Body Mass Index Are Not Impacted by Postpartum Obstetrical Practices or Routines., Nicole E Marshall, Laura F Lallande, Pepper J Schedin, Kent L Thornburg, and Jonathan Q Purnell

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Quality of Care Initiative Improves Outcomes for Patients with Inflammatory Bowel Disease, Gil Melmed, Brant Oliver, Jason Hou, Donald Lum, Donna Gerner, Damara Crate, Megan Holthoff, Quin Turner, Jessica Caron, Samir Shah, Mark Mattar, Siddharth Singh, Alice Kennedy, Josh Deitch, Raluca Vrabie, Francis Farraye, Helen Fasanya, Faiza Bhatti, Bincy Abraham, John Valentine, Christina Ha, Aline Charabaty, David Hudesman, Sharon Dudley-Brown, Swapna Reddy, Amy Wang, Emmanuelle Williams, John Betteridge, Arthur Orstov, Mark Metwally, Humberto Anguilar, Lia Kaufman, Mark Gerich, Caroline Hwang, David Rubin, Betty Kim, Erica Heagy, Rebecca Fausel, Frank Scott, Ann Flynn, Blair Fennimore, Gaurav Syal, Ziad Younes, Nirmal Kaur, Laura Yun, Harry Bray, Eugene Nelson, Kelly McCutcheon Adams, Caren Heller, Ridhima Oberai, Alandra Weaver, and Corey Siegal

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Association of immunophenotype with expression of topoisomerase II α and β in adult acute myeloid leukemia., Andrew P Michelson, Shannon McDonough, Cheryl L Willman, Eric R Koegle, John E Godwin, Stephen H Petersdorf, Alan F List, Megan Othus, Frederick R Appelbaum, Jerald P Radich, Mahrukh K Ganapathi, Anjali S Advani, and Ram N Ganapathi

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422 An open-label, multicenter, phase 1/2 clinical trial of RP1, an enhanced potency oncolytic HSV, combined with nivolumab: updated results from the skin cancer cohorts, Mark Middleton, Francesca Aroldi, Joseph Sacco, Mohammed Milhem, Brendan Curti, Ari VanderWalde MBioeth, Scott Baum, Adel Samson, Anna Pavlick, Jason Chesney, Jiaxin Niu, Terence Rhodes, Tawnya Bowles, Robert Conry, Anna Olsson-Brown, Douglas Earl Laux, Howard Kaufman, Praveen Bommareddy, Alex Deterding, Selda Samakoglu, Robert Coffin, and Kevin Harrington

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422 An open-label, multicenter, phase 1/2 clinical trial of RP1, an enhanced potency oncolytic HSV, combined with nivolumab: updated results from the skin cancer cohorts, Mark Middleton, Francesca Aroldi, Joseph Sacco, Mohammed Milhem, Brendan Curti, Ari VanderWalder MBioeth, Scott Baum, Adel Samson, Anna Pavlick, Jason Chesney, Jiaxin Niu, Terence Rhodes, Tawnya Bowles, Robert Conry, Anna Olsson-Brown, Douglas Earl Laux, Howard Kaufman, Praveen Bommareddy, Alex Deterding, Selda Samakoglu, Robert Coffin, and Kevin Harrington

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An open-label, single-arm, phase II clinical trial of RP1, an enhanced potency oncolytic herpes virus, combined with nivolumab in four solid tumor types: Initial results from the skin cancer cohorts., Mark R. Middleton, Francesca Aroldi, Joseph Sacco, Mohammed M. Milhem, Brendan Curti, Ari M. Vanderwalde, Scott Baum, Adel Samson, Anna C. Pavlick, Jason Alan Chesney, Jiaxin Niu, Terence Duane Rhodes, Tawnya Lynn Bowles, Anna Olsson-Brown, Douglas Earl Laux, Praveen Bommareddy, Alex Deterding, Joseph Elassal, Robert S. Coffin, and Kevin Harrington

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Multicenter International Society for Immunotherapy of Cancer Study of the Consensus Immunoscore for the Prediction of Survival and Response to Chemotherapy in Stage III Colon Cancer., Bernhard Mlecnik, Carlo Bifulco, Gabriela Bindea, Florence Marliot, Alessandro Lugli, J Jack Lee, Inti Zlobec, Tilman T Rau, Martin D Berger, Iris D Nagtegaal, Elisa Vink-Börger, Arndt Hartmann, Carol Geppert, Julie Kolwelter, Susanne Merkel, Robert Grützmann, Marc Van den Eynde, Anne Jouret-Mourin, Alex Kartheuser, Daniel Léonard, Christophe Remue, Julia Y Wang, Prashant Bavi, Michael H A Roehrl, Pamela S Ohashi, Linh T Nguyen, SeongJun Han, Heather L MacGregor, Sara Hafezi-Bakhtiari, Bradly G Wouters, Giuseppe V Masucci, Emilia K Andersson, Eva Zavadova, Michal Vocka, Jan Spacek, Lubos Petruzelka, Bohuslav Konopasek, Pavel Dundr, Helena Skalova, Kristyna Nemejcova, Gerardo Botti, Fabiana Tatangelo, Paolo Delrio, Gennaro Ciliberto, Michele Maio, Luigi Laghi, Fabio Grizzi, Tessa Fredriksen, Bénédicte Buttard, Lucie Lafontaine, Daniela Bruni, Anastasia Lanzi, Carine El Sissy, Nacilla Haicheur, Amos Kirilovsky, Anne Berger, Christine Lagorce, Christopher Paustian, Carmen Ballesteros-Merino, Jeroen Dijkstra, Carlijn van de Water, Shannon van Lent-van Vliet, Nikki Knijn, Ana-Maria Muşină, Dragos-Viorel Scripcariu, Boryana Popivanova, Mingli Xu, Tomonobu Fujita, Shoichi Hazama, Nobuaki Suzuki, Hiroaki Nagano, Kiyotaka Okuno, Toshihiko Torigoe, Noriyuki Sato, Tomohisa Furuhata, Ichiro Takemasa, Kyogo Itoh, Prabhu S Patel, Hemangini H Vora, Birva Shah, Jayendrakumar B Patel, Kruti N Rajvik, Shashank J Pandya, Shilin N Shukla, Yili Wang, Guanjun Zhang, Yutaka Kawakami, Francesco M Marincola, Paolo A Ascierto, Bernard A Fox, Franck Pagès, and Jérôme Galon

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Effects of Radiation on the Tumor Microenvironment., Arta M Monjazeb, Kurt A Schalper, Franz Villarroel-Espindola, Anthony Nguyen, Stephen L Shiao, and Kristina H Young

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Effects of Radiation on the Tumor Microenvironment., Arta M Monjazeb, Kurt A Schalper, Franz Villarroel-Espindola, Anthony Nguyen, Stephen L Shiao, and Kristina H Young

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Tumor antigen expression and survival of patients with previously treated advanced non-small cell lung cancer (NSCLC) receiving viagenpumatucel-L (HS-110) plus nivolumab., Daniel Morgensztern, Saiama Naheed Waqar, Lyudmila Bazhenova, Lori McDermott, Jeff Hutchins, David H. Taylor, Fred L. Robinson, Alexa K Dowdell, Brian D. Piening, Wael A. Harb, Nathan A. Pennell, and Roger B. Cohen

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QP 15 - Biology 07 - Radiation and Immunotherapy, Zachary Scott Morris and Kristina H Young

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Effects of YOCAS yoga, cognitive behavioral therapy, and survivorship health education on insomnia: A URCC NCORP Research Base Phase III RCT in 740 cancer survivors., Karen Michelle Mustian, Po-Ju Lin, Eva Culakova, Javier Bautista, Huiwen Xu, Supriya Gupta Mohile, Michelle Christine Janelsins, Luke Joseph Peppone, Amber Kleckner, Ian Kleckner, Kah Poh Loh, Richard Francis Dunne, Nikesha Gilmore, Alison Conlin, Kim Ong Gococo, and Anthony John Jaslowski

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A first-in-human phase 1 dose escalation study of spartalizumab (PDR001), an anti-PD-1 antibody, in patients with advanced solid tumors., Aung Naing, Justin F Gainor, Hans Gelderblom, Patrick M Forde, Marcus O Butler, Chia-Chi Lin, Sunil Sharma, Maria Ochoa de Olza, Andrea Varga, Matthew H Taylor, Jan H M Schellens, Hongqian Wu, Haiying Sun, Antonio P Silva, Jason Faris, Jennifer Mataraza, Scott Cameron, and Todd M Bauer