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Submissions from 2021

Advances in Immunotherapy, David B Page

Teaming up to Finish Triple-Negative Breast Cancer, David B Page

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399 A phase II study of nivolumab, ipilimumab, plus androgen receptor blockade with bicalutamide to enhance thymic T-cell production and immunotherapy response in metastatic breast cancer, David B Page, Krystle Collins, Brie Chun, Zhaoyu Sun, Yoshinobu Koguchi, William L. Redmond, Maritza Martel, Yaping Wu, Nikki Moxon, Staci Mellinger, Walter Urba, Ayca Gucalp, and Tiffany Traina

A phase II study of nivolumab, ipilimumab, plus androgen receptor blockade with bicalutamide to enhance thymic T-cell production and immunotherapy response in metastatic breast cancer, David B Page, Krystle Collins, Brie Chun, Zhaoyu Sun, Yoshinobu Koguchi, William D Ryan, Maritza Martel, Yaping Wu, Nikki Moxon, Staci Mellinger, Walter Urba, Ayca Gucalp, and Tiffany A. Traina

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OT1-18-04. A phase II study of dual immune checkpoint blockade (ICB) plus bicalutamide to enhance thymic T-cell production and immunotherapy response in metastatic breast cancer (MBC), David B Page, Krystle L. Collins, Brie Chun, Zhaoyu Sun, William L. Redmond, Maritza Martel, Yaping Wu, Nikki Moxon, Staci Mellinger, Walter Urba, Tiffany Traina, and Ayca Gucalp

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Postinfusion monitoring costs by site of care for patients with relapsed/refractory large B-cell lymphoma receiving third- or later-line treatment with lisocabtagene maraleucel in the TRANSCEND NHL 001 and OUTREACH trials., M Lia Palomba, Monika Parisi Jun, James Lymp, Andy Nguyen, November McGarvey, Matthew Gitlin, Corey Pelletier, Scott J Keating, and John Godwin

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Amivantamab in EGFR Exon 20 Insertion-Mutated Non-Small-Cell Lung Cancer Progressing on Platinum Chemotherapy: Initial Results From the CHRYSALIS Phase I Study., Keunchil Park, Eric B Haura, Natasha B Leighl, Paul Mitchell, Catherine A Shu, Nicolas Girard, Santiago Viteri, Ji-Youn Han, Sang-We Kim, Chee Khoon Lee, Joshua K Sabari, Alexander I Spira, Tsung-Ying Yang, Dong-Wan Kim, Ki Hyeong Lee, Rachel E Sanborn, José Trigo, Koichi Goto, Jong-Seok Lee, James Chih-Hsin Yang, Ramaswamy Govindan, Joshua M Bauml, Pilar Garrido, Matthew G Krebs, Karen L Reckamp, John Xie, Joshua C Curtin, Nahor Haddish-Berhane, Amy Roshak, Dawn Millington, Patricia Lorenzini, Meena Thayu, Roland E Knoblauch, and Byoung Chul Cho

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1247P - Management of infusion-related reactions (IRRs) in patients receiving amivantamab, K Park, JK Sabari, EB Haura, CA Shu, A Spira, R Salgia, KL Reckamp, Rachel E Sanborn, R Govindan, JM Bauml, JC Curtin, J Xie, A Roshak, P Lorenzini, D Millington, M Thayu, RE Knoblauch, and BC Cho

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TBX2 Drives Neuroendocrine Prostate Cancer through Exosome-Mediated Repression of miR-200c-3p., Girijesh Kumar Patel, Sayanika Dutta, Mosharaf Mahmud Syed, Sabarish Ramachandran, Monica Sharma, Venkatesh Rajamanickam, Vadivel Ganapathy, David J DeGraff, Kevin Pruitt, Manisha Tripathi, and Srinivas Nandana

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Anticoagulation Therapy Reduces Recurrent Stroke in Embolic Stroke of Undetermined Source Patients With Elevated Coagulation Markers or Severe Left Atrial Enlargement., Kishan Patel, Elio Mikhael, Michael Liu, Srikant Rangaraju, Deandra Ellis, Alexander Duncan, Samir Belagaje, Trina Belair, Laura Henriquez, and Fadi Nahab

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A phase 1 study of SGN-B6A, an antibody-drug conjugate targeting integrin beta-6, in patients with advanced solid tumors (SGNB6A-001, Trial in Progress)., Amita Patnaik, Emiliano Calvo, Rachel E Sanborn, and See list of authors in comments

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Facebook Live: Homeschooling and Internet safety for kids and teens, Tyson Payne and Roseann Gretchell

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miRNome and Functional Network Analysis of PGRMC1 Regulated miRNA Target Genes Identify Pathways and Biological Functions Associated With Triple Negative Breast Cancer., Diego A Pedroza, Matthew Ramirez, Venkatesh Rajamanickam, Ramadevi Subramani, Victoria Margolis, Tugba Gurbuz, Adriana Estrada, and Rajkumar Lakshmanaswamy

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Modify Centers for Medicare & Medicaid Services' Sepsis Core Measure (SEP-1) Now to Optimize Care for COVID-19., Harry Peled, Nhu Quyen Dau, and Shelley Schoepflin Sanders

Hyperbaric oxygen therapy: monoplace chamber, A Perez

Cardiac disease and vascular imaging, Alejandro Perez

Coding changes for wound care clinician-2021 updates, Alejandro Perez

Demographics and cost of venous leg ulcers, Alejandro Perez

Efforts and progress on key vascular quality measures, Alejandro Perez

Hyperbaric oxygen therapy: treatment indications, Alejandro Perez

Peripheral arterial disease: diagnosis and medical management, Alejandro Perez

Peripheral artery disease: basic principles for the wound care clinician, Alejandro Perez

Scanning below the knee arteries- how to determine stenosis when there no validated criteria?, Alejandro Perez

Venous purple toe syndrome: a variant of acrocyanosis, Alejandro Perez

Wound care local coverage determination, Alejandro Perez

Integrated Personal Omics Profiling for Obesity, Brian D. Piening

Multi-Omics at Providence, Brian D. Piening

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Palbociclib (P) in patients (pts) with head and neck cancer (HNC) with CDKN2A loss or mutation: Results from the Targeted Agent and Profiling Utilization Registry (TAPUR) study., Evan P. Pisick, Matthew Rothe, Rom Leidner, and See list of authors in comments

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961MO - Safety, efficacy, immunogenicity of arenavirus-based vectors HB-201 and HB-202 in patients with HPV16+ cancers, MR Posner, AL Ho, J Niu, L Nabell, Rom Leidner, J Nieva, DL Richardson, AT Pearson, D Wang, K Chung, DR Adkins, A Pimentel, S Wong, C Iacobucci, X Qing, K Katchar, K Schlienger, I Matushansky, S Fu, and DG Pfister

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Intralesional TTI-621, a novel biologic targeting the innate immune checkpoint CD47, in patients with relapsed or refractory mycosis fungoides or Sézary syndrome: a multicentre, phase 1 study., Christiane Querfeld, John A Thompson, Matthew H Taylor, Jennifer A DeSimone, Jasmine M Zain, Andrei R Shustov, Carolyn Johns, Sue McCann, Gloria H Y Lin, Penka S Petrova, Robert A Uger, Naomi Molloy, Yaping Shou, and Oleg E Akilov

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Robust Antitumor Immunity in a Patient with Metastatic Colorectal Cancer Treated with Cytotoxic Regimens., Venkatesh Rajamanickam, Carmen Ballesteros-Merino, Kimberly Samson, David Ross, Brady Bernard, Bernard A Fox, Pippa Newell, Thomas Duhen, and Eric Tran

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1360TiP First-line (1L) maintenance therapy with niraparib (nira) + pembrolizumab (pembro) vs placebo + pembro in advanced/metastatic non-small cell lung cancer (NSCLC): Phase III ZEAL-1L study, SS Ramalingam, G de Castro Jr, MCC Garassino, J Mazieres, Rachel E Sanborn, EFF Smit, DR Spigel, M Thomas, V Velcheti, E Zhi, M Whipple Neibauer, A Stojadinovic, and S Peters

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A standardized optical coherence tomography workflow improves procedural efficiency and safety during percutaneous coronary intervention: insights from the LightLab Initiative, Judah Rauch, Michael Johnson, Aziz Maksoud, Daniel Spoon, Frank Zidar, Ethan C Korngold, Jana Buccola, Hector Garcia Cabrera, Richard Rapoza, Nick West, and Eric Osborn

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Efficient antigen cross-presentation through coating conventional aluminum adjuvant particles with PEI., Hongyan Ren, Yongbin Mou, Lin Lin, Lixin Wang, and Hongming Hu

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Facebook Live: Body Positivity - Loving your body at every stage, Mary Renouf-Hanson and Robin Henderson

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558TiP - Phase I study of effector-function enhanced monoclonal antibody (mAb), SEA-TGT, in advanced malignancies, V Ribrag, D Davar, E Garralda, G Curigliano, J Zain, A Mehta, A Minchom, Rachel E Sanborn, F Foss, HK Oberoi, A Forero-Torres, and S Ansell

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Evaluation of Indocyanine Green Fluorescence Imaging for Intraoperative Identification of Liver Malignancy., Jorge G Zarate Rodriguez, Jan Grendar, Zeljka Jutric, Maria A Cassera, Ronald F Wolf, Paul D Hansen, and Chet W Hammill

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596 Combining Bempegaldesleukin (CD122-preferential IL-2 pathway agonist) and NKTR-262 (TLR7/8 agonist) pairs local innate activation with systemic CD8+ T cell expansion to enhance anti-tumor immunity, Annah S Rolig, Daniel Rose, Grace Helen McGee, Saul Kivimae, Werner Rubas, and William L. Redmond

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Predictors of Outcomes in Patients With Mild Ischemic Stroke Symptoms: MaRISS., Jose G Romano, Hannah Gardener, Iszet Campo-Bustillo, Yosef Khan, Sofie Tai, Nikesha Riley, Eric E Smith, Ralph L Sacco, Pooja Khatri, Heather M Alger, Brian Mac Grory, Deepak Gulati, Navdeep S Sangha, Jeffrey M Craig, Karin E Olds, Curtis G Benesch, Adam G Kelly, Scott S Brehaut, Amit C Kansara, Lee H Schwamm, and MaRISS Investigators

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Frequency and Prognostic Significance of Clinical Fluctuations Before Hospital Arrival in Stroke., Jose G Romano, Hannah Gardener, Eric E Smith, Iszet Campo-Bustillo, Yosef Khan, Sofie Tai, Nikesha Riley, Ralph L Sacco, Pooja Khatri, Heather M Alger, Brian Mac Grory, Deepak Gulati, Navdeep S Sangha, Karin E Olds, Curtis G Benesch, Adam G Kelly, Scott S Brehaut, Amit Kansara, and Lee H Schwamm

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Successful pivot of a community exercise program to virtual during the COVID-19 pandemic, LeTracia Rose and James G Beckerman

Heart to heart: cardiology and nephrology discuss heart failure management, A Ross and C Kassakian

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Evaluation of Shared Experiences Among Patients and Providers Following Behavioral Health Integration in Primary Care., Natalie Royal Kenton, Nicole Bouranis, Emily J Cox, Laura Jacobson, and Bill J. Wright

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GM-CSF drives myelopoiesis, recruitment and polarisation of tumour-associated macrophages in cholangiocarcinoma and systemic blockade facilitates antitumour immunity., Luis I Ruffolo, Katherine M Jackson, Peyton C Kuhlers, Benjamin S Dale, Nathania M Figueroa Guilliani, Nicholas A Ullman, Paul R Burchard, Shuyang S Qin, Peter G Juviler, Jessica Millian Keilson, Ashley B Morrison, Mary Georger, Rachel Jewell, Laura M Calvi, Timothy M Nywening, Michael R O'Dell, Aram F Hezel, Luis De Las Casas, Gregory B Lesinski, Jen Jen Yeh, Roberto Hernandez-Alejandro, Brian A Belt, and David C Linehan

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Amivantamab in Post-platinum EGFR Exon 20 Insertion Mutant Non-small Cell Lung Cancer, JK Sabari, CA Shu, K Park, N Leighl, P Mitchell, S Kim, J Lee, D Kim, S Viteri, A Spira, J Han, J Trigo, CK Lee, KH Lee, N Girard, T Yang, K Goto, Rachel E Sanborn, JC Yang, J Xie, A Roshak, M Thayu, RE Knoblauch, and BC Cho

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Excess Mortality Among Patients Hospitalized During the COVID-19 Pandemic., Amber K Sabbatini, Ari Robicsek, Shih-Ting Chiu, and Ty J Gluckman

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Anti-GBM nephritis with mesangial IgA deposits after SARS-CoV-2 mRNA vaccination., Allan Sacker, Vanderlene Kung, and Nicole Andeen

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601 Sequencing immunotherapy before lymphatic ablation unleashes cDC1-dependent antitumor immunity in HNSCC, Robert Saddami-Konefka, Shawn M. Jensen, Bernard A Fox, and See all authors in comments

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A simplified approach to identification of risk status in patients with atherosclerotic cardiovascular disease, Aparna Sajja, Hsin-Fang Li, Kateri Spinelli, Amir Ali, Salim S. Virani, Seth S. Martin, and Tyler J Gluckman

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Concordance of LDL-cholesterol levels between the Friedewald, Martin/Hopkins, and Sampson equations in patients with atherosclerotic cardiovascular disease, Aparna Sajja, Hsin-Fang Li, Kateri Spinelli, Salim S. Virani, Seth S. Martin, and Tyler J Gluckman

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Physical Activity Patterns and Relationships With Cognitive Function in Patients With Breast Cancer Before, During, and After Chemotherapy in a Prospective, Nationwide Study., Elizabeth A Salerno, Eva Culakova, Amber S Kleckner, Charles E Heckler, Po-Ju Lin, Charles E Matthews, Alison Conlin, Lora Weiselberg, Jerry Mitchell, Karen M Mustian, and Michelle C Janelsins

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RAMOSE: An Open-Label Randomized Phase II Study of Osimertinib with or without Ramucirumab in TKI-Naïve EGFR-Mutant Metastatic NSCLC, A Saltos, C Baik, Rachel E Sanborn, E Shum, C Kim, R Hall, MJ Fidler, CA Shu, G Otterson, J Patel, K Wong, N Hanna, J Gray, J Heymach, and X Le

Immunotherapy Combos: LAG-3, TIM-3, TIGIT, OX-40, Rachel E Sanborn

OncLive Data Review: ESMO Congress 2021, Rachel E Sanborn

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A phase 1 dose-escalation study of a PD-L1xCD27 bispecific antibody CDX-527 in patients with advanced malignancies., Rachel E Sanborn, Rodolfo E. Bordoni, and See author list in comments

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Sanborn and Gaffar Share Clinical and Economic Treatment Insights in NSCLC, Rachel E Sanborn and Yousuf A. Gaffar

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CX-072 (pacmilimab), a Probody PD-L1 inhibitor, in combination with ipilimumab in patients with advanced solid tumors (PROCLAIM-CX-072): a first-in-human, dose-finding study., Rachel E Sanborn, Omid Hamid, Elisabeth Ge de Vries, Patrick A Ott, Javier Garcia-Corbacho, Valentina Boni, Johanna Bendell, Karen A Autio, Daniel C Cho, Ruth Plummer, Mark Stroh, Lawrence Lu, and Fiona Thistlethwaite

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398 neoIRX: a phase II trial of locoregional cytokine therapy to promote immunologic priming and clinical response to neoadjuvant pembrolizumab plus chemotherapy in triple negative breast cancer (TNBC), Katherine Sanchez, Alison Conlin, Parvin Peddi, Sasha Stanton, Janet Ruzich, Kelly S Perlewitz, Yaping Wu, Nikki Moxon, Staci Mellinger, Zhaoyu Sun, William L. Redmond, and David B Page

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OT1-18-03. The neoIRX trial:locoregional cytokine therapy to promote immunologic priming and enhanced response to neoadjuvant pembrolizumab plus chemotherapy in triple negative breast cancer (TNBC), Katherine Sanchez, Alison Conlin, Parvin Peddi, Sasha Stanton, Janet Ruzich, Kelly S Perlewitz, Yaping Wu, Nikki Moxon, Staci Mellinger, Zhaoyu Sun, William L. Redmond, and David B Page

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Multiplex immunofluorescence to measure dynamic changes in tumor-infiltrating lymphocytes and PD-L1 in early-stage breast cancer., Katherine Sanchez, Isaac Kim, Brie Chun, Joanna Pucilowska, William L. Redmond, Walter Urba, Maritza Martel, Yaping Wu, Mary Campbell, Zhaoyu Sun, Gary Grunkemeier, Shu-Ching Chang, Brady Bernard, and David B Page

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Lifileucel, a Tumor-Infiltrating Lymphocyte Therapy, in Metastatic Melanoma., Amod A Sarnaik, Omid Hamid, Nikhil I Khushalani, Karl D Lewis, Theresa Medina, Harriet M Kluger, Sajeve S Thomas, Evidio Domingo-Musibay, Anna C Pavlick, Eric D Whitman, Salvador Martin-Algarra, Pippa Corrie, Brendan D Curti, Judit Oláh, Jose Lutzky, Jeffrey S Weber, James M G Larkin, Wen Shi, Toshimi Takamura, Madan Jagasia, Harry Qin, Xiao Wu, Cecile Chartier, Friedrich Graf Finckenstein, Maria Fardis, John M Kirkwood, and Jason A Chesney

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Facebook Live: Environmental Stewardship through a Clinical Lens, Elizabeth Schenk and Brian B. Chesebro

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A Phase Ib/II Study of Pepinemab in Combination with Avelumab in Advanced Non-Small Cell Lung Cancer., Michael R Shafique, Terrence L Fisher, Elizabeth E Evans, John E Leonard, Desa Rae E Pastore, Crystal L Mallow, Ernest Smith, Vikas Mishra, Andreas Schröder, Kevin M Chin, Joseph T Beck, Megan A Baumgart, Ramaswamy Govindan, Nashat Y Gabrail, Alexander I Spira, Nagashree Seetharamu, Yanyan Lou, Aaron S Mansfield, Rachel E Sanborn, Jonathan W Goldman, and Maurice Zauderer

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Management of spontaneous coronary artery dissection complicated by cardiogenic shock using mechanical circulatory support with the Impella device., Shilpa Sharma, Samantha Polak, Zachary George, John LeDoux, Richard Sohn, Adam Stys, Cathy Jeon, Yousef Ghazzawi, and Malissa Wood

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A platform for locoregional T-cell immunotherapy to control HNSCC recurrence following tumor resection., Shay Sharon, Jason R Baird, Shelly Bambina, Gwen Kramer, Tiffany C Blair, Shawn M Jensen, Rom S Leidner, R Bryan Bell, Nardy Casap, Marka R Crittenden, and Michael J Gough

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Explant Modeling of the Immune Environment of Head and Neck Cancer., Shay Sharon, Thomas Duhen, Shelly Bambina, Jason Baird, Rom Leidner, Bryan Bell, Nardy Casap, Marka Crittenden, Swetha Vasudevan, Maria Jubran, Nataly Kravchenko-Balasha, and Michael Gough

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Open-label, phase II study of ladiratuzumab vedotin (LV) for castration-resistant prostate cancer (SGNLVA-005, trial-in-progress)., Amna Falak Sher, Justine Yang Bruce, Nashat Y. Gabrail, Ian Churchill Anderson, Anna Patrikidou, Rachel E Sanborn, Jae Yong Cho, Arielle Shebay Lee, Jong-Seok Lee, Louise M. Nott, Do-Youn Oh, Sang Cheul Oh, Sung Yong Oh, Yinghui Wang, Zejing Wang, and Troy H. Guthrie

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1193MO - Amivantamab plus lazertinib in post-osimertinib, post-platinum chemotherapy EGFR-mutant non-small cell lung cancer (NSCLC): Preliminary results from CHRYSALIS-2, CA Shu, K Goto, Y Ohe, B Besse, K Park, Y Wang, F Griesinger, JC Yang, E Felip, Rachel E Sanborn, R Bernabe Caro, JM Bauml, J Chen, E Fennema, J Mahoney, L Trani, RE Knoblauch, M Thayu, and BC Chou

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523 Preliminary clinical experience with XmAb20717, a PD-1 x CTLA-4 bispecific antibody, in patients with advanced solid tumors, Elaine Shum, Rom Leidner, and See full list of authors in comments

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Multicenter, double-blind, placebo-controlled trial of seviprotimut-L polyvalent melanoma vaccine in patients with post-resection melanoma at high risk of recurrence., Craig L Slingluff, Karl D Lewis, Robert Andtbacka, John Hyngstrom, Mohammed Milhem, Svetomir N Markovic, Tawnya Bowles, Omid Hamid, Leonel Hernandez-Aya, Joel Claveau, Sekwon Jang, Prejesh Philips, Shernan G Holtan, Montaser F Shaheen, Brendan Curti, William Schmidt, Marcus O Butler, Juan Paramo, Jose Lutzky, Arvinda Padmanabhan, Sajeve Thomas, Daniel Milton, Andrew Pecora, Takami Sato, Eddy Hsueh, Suprith Badarinath, John Keech, Sujith Kalmadi, Pallavi Kumar, Robert Weber, Edward Levine, Adam Berger, Anna Bar, J Thaddeus Beck, Jeffrey B Travers, Catalin Mihalcioiu, Brian Gastman, Peter Beitsch, Suthee Rapisuwon, John Glaspy, Edward C McCarron, Vinay Gupta, Deepti Behl, Brent Blumenstein, and Joanna J Peterkin

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Clinical outcomes of patients with multiple sclerosis treated with ocrelizumab in a US community MS center: an observational study., Kyle Smoot, Chiayi Chen, Tamela Stuchiner, Lindsay Lucas, Lois Grote, and Stanley Cohan

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Tumor-associated autoantibodies from mouse breast cancer models are found in serum of breast cancer patients., Sasha Stanton, Ekram Gad, Erik Ramos, Lauren Corulli, James Annis, Jennifer Childs, Hiroyuki Katayama, Samir Hanash, Jeffrey Marks, and Mary L Disis

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1556 - Retinoid X receptor agonists enhances Th1 antigen-specific and polyfunctional T cells with the HER2-IGFBP2-IGF1R vaccine, Sasha Stanton, Erin Rodmaker, Nicholas Drovetto, Lauren Corulli, Flonia Levy, Venkatram Atigadda, Clinton Grubbs, Romaine Fernando, Shizuko Sei, and Mary L. Disis

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Global Proteomic Profiling Identifies Novel Prognostic Factors in Undifferentiated Leukemia Blasts from Patients with NPM1 Mutations: A Previously Unreported Approach to Biomarker Discovery from the Fred Hutch and SWOG, Derek Stirewalt, John E Godwin, and See full list of authors in comments

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Facebook Live: New Year, New You: Personalize your plate and start moving, Niki Strealy and Stacey Cochran

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Galectin-3 inhibition with belapectin combined with anti-OX40 therapy reprograms the tumor microenvironment to favor anti-tumor immunity., Elizabeth Sturgill, Annah S Rolig, Stefanie N Linch, Courtney Mick, Melissa Kasiewicz, Zhaoyu Sun, Peter G Traber, Harold Shlevin, and William L. Redmond

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Pralsetinib for patients with advanced or metastatic RET-altered thyroid cancer (ARROW): a multi-cohort, open-label, registrational, phase 1/2 study., Vivek Subbiah, Mimi I Hu, Lori J Wirth, Martin Schuler, Aaron S Mansfield, Giuseppe Curigliano, Marcia S Brose, Viola W Zhu, Sophie Leboulleux, Daniel W Bowles, Christina S Baik, Douglas Adkins, Bhumsuk Keam, Ignacio Matos, Elena Garralda, Justin F Gainor, Gilberto Lopes, Chia-Chi Lin, Yann Godbert, Debashis Sarker, Stephen G Miller, Corinne Clifford, Hui Zhang, Christopher D Turner, and Matthew H Taylor

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Developing an enhanced 7-color multiplex IHC protocol to dissect immune infiltration in human cancers., Zhaoyu Sun, Richard Nyberg, Yaping Wu, Brady Bernard, and William L. Redmond

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Safety and Efficacy of Pembrolizumab in Combination with Acalabrutinib in Advanced Head and Neck Squamous Cell Carcinoma: Phase 2 Proof-of-Concept Study., Matthew H Taylor, Courtney B Betts, Lauren Maloney, Eric Nadler, Alain Algazi, Michael J Guarino, John Nemunaitis, Antonio Jimeno, Priti Patel, Veerendra Munugalavadla, Lin Tao, Douglas Adkins, Jerome H Goldschmidt, Ezra E W Cohen, and Lisa M Coussens

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Encorafenib and binimetinib with or without nivolumab in treating patients with metastatic radioiodine refractory BRAF V600 mutant thyroid cancer., Matthew H Taylor, Rom Leidner, Richard Bryan Bell, Bernard A Fox, and See full authors list in comments

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The LEAP program: lenvatinib plus pembrolizumab for the treatment of advanced solid tumors., Matthew H Taylor, Emmett V Schmidt, Corina Dutcus, Elaine M Pinheiro, Yasuhiro Funahashi, Gregory Lubiniecki, and Drew Rasco

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Correlation of Performance Status and Neutrophil-Lymphocyte Ratio With Efficacy in Radioiodine-Refractory Differentiated Thyroid Cancer Treated With Lenvatinib., Matthew H Taylor, Shunji Takahashi, Jaume Capdevila, Makoto Tahara, Sophie Leboulleux, Naomi Kiyota, Corina E Dutcus, Ran Xie, Bruce Robinson, Steven I Sherman, Mouhammed Amir Habra, Rossella Elisei, and Lori J Wirth

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Intratumoral Plasmid IL12 Expands CD8, Melinda L Telli, Hiroshi Nagata, Irene Wapnir, Chaitanya R Acharya, Kaitlin Zablotsky, Bernard A Fox, Carlo Bifulco, Shawn M. Jensen, Carmen Ballesteros-Merino, Mai Hope Le, Robert H Pierce, Erica Browning, Reneta Hermiz, Lauren Svenson, Donna Bannavong, Kim Jaffe, Jendy Sell, Kellie Malloy Foerter, David A Canton, Christopher G Twitty, Takuya Osada, H Kim Lyerly, and Erika J Crosby

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CardioMEMS guided treatment of chronic HF patients supported with a HeartMate LVAD: INTELLECT 2-HF study, V Thohan, Jacob Abraham, A Burdof, DJ Farrar, N Dirckx, AT Baker, and SG Drakos

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A Caenorhabditis elegans behavioral assay distinguishes early stage prostate cancer patient urine from controls, Morgan Thompson, Noemi Sarabia Feria, Ally Yoshioka, Eugene Tu, Fehmi Civitci, Suzanne Estes, and Josiah T Wagner

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Evaluation and optimization of blanket production from recycled polyethylene terephthalate based on the coordination of environment, economy, and society., Shu Tian, Hongrui Tang, Qingsong Wang, Xueliang Yuan, Qiao Ma, and Mansen Wang

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Abemaciclib in Combination With Endocrine Therapy for Patients With Hormone Receptor-Positive, HER2-Negative Metastatic Breast Cancer: A Phase 1b Study., Sara M Tolaney, Muralidhar Beeram, J Thaddeus Beck, Alison Conlin, E Claire Dees, Shannon L Puhalla, Brent N Rexer, Howard A Burris, Komal Jhaveri, Teresa Helsten, Carlos Becerra, Kevin Kalinsky, Kathleen N Moore, Allison M Manuel, Andrew Lithio, Gregory L Price, Sonya C Chapman, Lacey M Litchfield, and Matthew P Goetz

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583 Exploring the potential of T cell acute lymphoblastic leukemia (T-ALL) for generating leukemia-specific T cell responses that can be therapeutically harnessed with immunotherapy, Todd Triplett, Andrew D Weinberg, and See full list of authors in comments

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Supportive Management of Patients with Advanced Pheochromocytomas and Paragangliomas Receiving PRRT., Erica S Tsang, Gayle Funk, Janet Leung, Grace Kalish, and Hagen F Kennecke

Strategic interventional approach to femoropopliteal occlusive disease, Brant Ullery

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Long-Term Outcomes of Intra-Arterial Chemotherapy for Progressive or Unresectable Pilocytic Astrocytomas: Case Studies., Kutluay Uluc, Dominic A Siler, Ricardo Lopez, Csanad Varallyay, Joao Prola Netto, Jenny Firkins, Cindy Lacy, Amy Huddleston, Prakash Ambady, and Edward A Neuwelt

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Should Airbag Backpacks Be Standard Avalanche Safety Equipment?, Christopher Van Tilburg

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Associations of Uncertainty With Psychological Health and Quality of Life in Older Adults With Advanced Cancer., Haydee C Verduzco-Aguirre, Dilip Babu, Supriya G Mohile, Javier Bautista, Huiwen Xu, Eva Culakova, Beverly Canin, Yingzi Zhang, Megan Wells, Ronald M Epstein, Paul Duberstein, Colin McHugh, William Dale, Alison Conlin, James Bearden, Jeffrey Berenberg, Mohamedtaki Tejani, and Kah Poh Loh

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Pediatric Endoscopy Quality Improvement Network (PEnQuIN) Quality Standards and Indicators for Pediatric Endoscopists and Endoscopists in Training: A Joint NASPGHAN/ESPGHAN Guideline., Catharine M Walsh, Jenifer R Lightdale, Ian H Leibowitz, Diana G Lerner, Quin Y Liu, David R Mack, Petar Mamula, Priya Narula, Salvatore Oliva, Matthew R Riley, Joel R Rosh, Marta Tavares, Elizabeth C Utterson, Jorge Amil-Dias, Patrick Bontems, Herbert Brill, Nicholas M Croft, Douglas S Fishman, Raoul I Furlano, Peter M Gillett, Iva Hojsak, Matjaž Homan, Hien Q Huynh, Kevan Jacobson, Lusine Ambartsumyan, Anthony R Otley, Robert E Kramer, Graham A McCreath, Veronik Connan, Mike A Thomson, and PEnQuIN Working Group

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Overview of the Pediatric Endoscopy Quality Improvement Network (PEnQuIN) Quality Standards and Indicators for Pediatric Endoscopy: A Joint NASPGHAN/ESPGHAN Guideline., Catharine M Walsh, Jenifer R Lightdale, David R Mack, Jorge Amil-Dias, Patrick Bontems, Herbert Brill, Nicholas M Croft, Douglas S Fishman, Raoul I Furlano, Peter M Gillett, Iva Hojsak, Matjaž Homan, Hien Q Huynh, Kevan Jacobson, Ian H Leibowitz, Diana G Lerner, Quin Y Liu, Petar Mamula, Priya Narula, Salvatore Oliva, Matthew R Riley, Joel R Rosh, Marta Tavares, Elizabeth C Utterson, Lusine Ambartsumyan, Anthony R Otley, Robert E Kramer, Veronik Connan, Graham A McCreath, Mike A Thomson, and PEnQuIN Working Group

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Cryoballoon Ablation as Initial Therapy for Atrial Fibrillation., Oussama M Wazni, Gopi Dandamudi, Nitesh Sood, Robert Hoyt, Jaret Tyler, Sarfraz Durrani, Mark Niebauer, Kevin Makati, Blair Halperin, Andre Gauri, Gustavo Morales, Mingyuan Shao, Jeffrey Cerkvenik, Rachelle E Kaplon, Steven E Nissen, and STOP AF First Trial Investigators

OX40 agonists enhance tumor Ag-specific T cell responses in cancer patients, Andrew D Weinberg

Enriching for Tumor-Reactive CD8 TIL with CD39/103 Markers: Implications for TIL Therapy, Andrew D. Weinberg

Adipocytes as Anticancer Drug Delivery Depot, D Wen, J Wang, and Z Gu

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Genetic deletion of Polo-like kinase 2 reduces alpha-synuclein serine-129 phosphorylation in presynaptic terminals but not Lewy bodies., Leah J Weston, Teresa L Stackhouse, Kateri Spinelli, Sydney W Boutros, Elizabeth P Rose, Valerie R Osterberg, Kelvin C Luk, Jacob Raber, Tamily A Weissman, and Vivek K Unni