Submissions from 2022
Venous Disease Management, Alejandro Perez
The effect of maternal SARS-CoV-2 infection timing on birth outcomes: a retrospective multicentre cohort study., Samantha N Piekos, Ryan Roper, Yeon Mi Hwang, Tanya K Sorensen, Nathan D Price, Leroy Hood, and Jennifer J Hadlock
Real-World Evidence Insights in Cancer Research and Care, Brian D. Piening
Pathogenic fusion detection in solid malignancies utilizing RNA-DNA based comprehensive genomic profiling (CGP) testing., Brian D. Piening, Alexa K Dowdell, Ryan Meng, Ann Vita, Roshanthi Weerasinghe, Alisha Stein, Bela Bapat, Brock Shroeder, Shu-Ching Chang, Lauren Harold, Mark Schmidt, Thomas R. Ward, Josiah T Wagner, Stanley Piotrowski, Phillip G. Febbo, and Carlo Bifulco
Elucidating Diversity in Obesity-Related Phenotypes Using Longitudinal and Multi-omic Approaches, Brian D. Piening, Alexa K Dowdell, and Michael P. Snyder
Whole transcriptome profiling of prospective endomyocardial biopsies reveals prognostic and diagnostic signatures of cardiac allograft rejection., Brian D. Piening, Alexa K Dowdell, Mengqi Zhang, Bao-Li Loza, David Walls, Hui Gao, Maede Mohebnasab, Yun Rose Li, Eric Elftmann, Eric Wei, Divya Gandla, Hetal Lad, Hassan Chaib, Nancy K Sweitzer, Mario Deng, Alexandre C Pereira, Martin Cadeiras, Abraham Shaked, Michael P Snyder, and Brendan J Keating
Design and Implementation of a Decentralized Virtual Molecular Tumor Board across a Large, Diverse Community Health System, Brian Piening, Patrick Foley, K Matlock, H Wright, Lauren Harold, Roshanthi Weerasinghe, A Viita, C Moung-Wen, Jacob Abel, Vassil Kaimaktchiev, A Dowdell, Ryan Meng, Walter Urba, G Srinivasa, Philip Gold, Gina Vaccaro, and Carlo Bifulco
Adjuvant and Neoadjuvant Therapies in Cutaneous Melanoma., Jay Ponto and Richard Bryan Bell
The Care Ecosystem: The Effectiveness and Implementation of Telephone-Based Collaborative Dementia Care., Katherine L Possin, Alissa Bernstein Sideman, Sarah Dulaney, Kirby Lee, Jennifer Merrilees, Steve Bonasera, Winston Chiong, Sarah M Hooper, Rachel Kiekhofer, Joanne Robinson-Teran, Isabel Elaine Allen, Tamara Braley, Elan Guterman, Talita D Rosa, Krista L Harrison, Lauren Hunt, James G Kahn, Serggio Lanata, Bruce L Miller, Ashley LaRoche, Robert John Sawyer, Adreanne Brungardt, Hillary Lum, Mailee Hess, Katie Ward, Mary E. Kuebrich, Marian O. Hodges, Nicholas T Olney, Michelle Barclay, and Michael H Rosenbloom
Epacadostat Plus Pembrolizumab and Chemotherapy for Advanced Solid Tumors: Results from the Phase I/II ECHO-207/KEYNOTE-723 Study., John D Powderly, Samuel J Klempner, Aung Naing, Johanna Bendell, Ignacio Garrido-Laguna, Daniel V T Catenacci, Matthew H Taylor, James J Lee, Fred Zheng, Feng Zhou, Xiaohua Gong, Hema Gowda, and Gregory L Beatty
CT209 / 9 - A first-in-human phase 1 trial of IO-108, an antagonist antibody targeting LILRB2 (ILT4), as monotherapy and in combination with pembrolizumab in adult patients with advanced relapsed or refractory solid tumors (NCT05054348), John Powderly, Matthew H Taylor, and See full list of authors in comments
AACR Project GENIE: 100,000 cases and beyond., Trevor J Pugh, Jonathan L Bell, Jeff P Bruce, Gary J Doherty, Matthew Galvin, Michelle F Green, Haley Hunter-Zinck, Priti Kumari, Michele L LeNoue-Newton, Marilyn M Li, James Lindsay, Tali Mazor, Andrea Ovalle, Stephen-John Sammut, Nikolaus Schultz, Thomas V Yu, Shawn M Sweeney, Brady Bernard, and Aacr Project Genie Consortium
Fulminant Myocarditis Following SARS-CoV-2 Infection:, Saurabh Rajpal, Rami Kahwash, Matthew S Tong, Kelly Paschke, Anjali A Satoskar, Beth Foreman, Larry A Allen, Nicole M Bhave, Tyler J Gluckman, and Valentin Fuster
Fulminant Myocarditis Following SARS-CoV-2 Infection: JACC Patient Care Pathways., Saurabh Rajpal, Rami Kahwash, Matthew S Tong, Kelly Paschke, Anjali A Satoskar, Beth Foreman, Larry A Allen, Nicole M Bhave, Tyler J Gluckman, and Valentin Fuster
Efficacy of oral and topical antioxidants in the prevention and management of oral mucositis in head and neck cancer patients: a systematic review and meta-analyses., Afsheen Raza, Nelli Karimyan, Amber L Watters, Chitra P Emperumal, Kamal Al-Eryani, and Reyes Enciso
Response to aPD-1 + aLAG-3 checkpoint blockade is associated with Treg functional reprogramming and instability, William Redmond
Multimodal single-cell analysis of human TILs across multiple tumor types reveals heterogeneity and potential opportunities for personalized immunotherapy, William L. Redmond
Novel mechanisms to augment the efficacy of cancer immunotherapy, William L. Redmond
Multimodal single-cell analysis of human tumor infiltrating immune cells across multiple tumor types reveals heterogeneity and potential opportunities for personalized immunotherapeutic strategies., William L. Redmond and See full list of authors in comments
Modified dose of guselkumab for treatment of pyoderma gangrenosum., Ashley M Reese, Katherine Erickson, Katherine B Reed, and Alex G Ortega-Loayza
Icons and Plain Language in Written Home Care Instructions, Jennifer Reynolds
Combining bempegaldesleukin (CD122-preferential IL-2 pathway agonist) and NKTR-262 (TLR7/8 agonist) improves systemic antitumor CD8, Annah S Rolig, Daniel Rose, Grace Helen McGee, Werner Rubas, Saul Kivimäe, and William L. Redmond
Response to anti-PD-1 and anti-LAG-3 immune checkpoint blockade is associated with induction of pro-inflammatory Tregs., AS Rolig, William L. Redmond, and See full list of authors in comments
AHPBA graduated fellows' assessments of strengths, weaknesses, opportunities and threats facing fellowship training in HPB surgery: "HPB training excellence means volume, knowledge, and mentorship"., Fernanda Romero-Hernandez, Phoebe Miller, Rosa V Mora, Dorothy Hughes, Susanne Warner, Adnan Alseidi, Brendan Visser, Michele Babicky, and AHPBA SWOT Taskforce
Discordance Between Standard Equations for Determination of LDL Cholesterol in Patients With Atherosclerosis., Aparna Sajja, Hsin-Fang Li, Kateri Spinelli, Roger S Blumenthal, Salim S Virani, Seth S Martin, and Tyler J Gluckman
Novel Combinatorial Approaches with LAG-3, Rachel Sanborn
Targeting OX-40 and LAG-3 to Overcome T-cell Exhaustion, Rachel Sanborn
Vaccines and emerging immunotherapy approaches for NSCLC, Rachel Sanborn
Safety, tolerability and efficacy of agonist anti-CD27 antibody (varlilumab) administered in combination with anti-PD-1 (nivolumab) in advanced solid tumors., Rachel E Sanborn, Michael J Pishvaian, Margaret K Callahan, Amy Weise, Branimir I Sikic, Osama Rahma, Daniel C Cho, Naiyer A Rizvi, Mario Sznol, Jose Lutzky, Julie E Bauman, Rhonda L Bitting, Alexander Starodub, Antonio Jimeno, David A Reardon, Thomas Kaley, Fabio Iwamoto, Joachim M Baehring, Deepa S Subramaniam, Jeanny B Aragon-Ching, Thomas R Hawthorne, Tracey Rawls, Michael Yellin, and Tibor Keler
Beyond Checkpoint Inhibitors: Enhancing Antitumor Immune Response in Lung Cancer., Rachel E Sanborn, Famke L Schneiders, Suresh Senan, and Shirish M Gadgeel
Results from a phase 1 study of CDX-1140, a fully human anti-CD40 agonist monoclonal antibody (mAb), in combination with pembrolizumab, Rachel E. Sanborn and See all authors in comments
Beyond Checkpoint Inhibitors: Enhancing Antitumor Immune Response in Lung Cancer, Rachel E Sanborn and See full list of authors in comments
Disparities in the impact of the AJCC 8th edition staging system on differentiated thyroid cancer outcomes., Juan A Santamaria-Barria, Amanda N Graff-Baker, Shu-Ching Chang, Adam Khader, Anthony J Scholer, Mary Garland-Kledzik, and Melanie Goldfarb
Evidence of neuroinflammation and immunotherapy responsiveness in individuals with down syndrome regression disorder., Jonathan D Santoro, Rebecca Partridge, Runi Tanna, Dania Pagarkar, Mellad Khoshnood, Mustafa Rehmani, Ryan M Kammeyer, Grace Y Gombolay, Kristen Fisher, Allison Conravey, Jane El-Dahr, Alison Christy, Lina Patel, Melanie A Manning, Heather Van Mater, Michael S Rafii, and Eileen A Quinn
Assessment and Diagnosis of Down Syndrome Regression Disorder: International Expert Consensus., Jonathan D Santoro, Lina Patel, Ryan Kammeyer, Robyn A Filipink, Grace Y Gombolay, Kathleen M Cardinale, Diego Real de Asua, Shahid Zaman, Stephanie L Santoro, Sammer M Marzouk, Mellad Khoshnood, Benjamin N Vogel, Runi Tanna, Dania Pagarkar, Sofia Dhanani, Maria Del Carmen Ortega, Rebecca Partridge, Maria A Stanley, Jessica S Sanders, Alison Christy, Elise M Sannar, Ruth Brown, Andrew A McCormick, Heather Van Mater, Cathy Franklin, Gordon Worley, Eileen A Quinn, George T Capone, Brian Chicoine, Brian G Skotko, and Michael S Rafii
Population Health: Turning In-Basket Into ROI, J Sauer, X Huang, and LJ Larson
2021 Digital Commons Annual Report, Amanda Schwartz
2021 System Library Services Visual Annual Report, Amanda Schwartz
The diverse landscape of dermatologic toxicities of non-immune checkpoint inhibitor monoclonal antibody-based cancer therapy., Riyad N H Seervai, Sarah K Friske, Emily Y Chu, Rhea Phillips, Kelly C Nelson, Auris Huen, Woo Cheal Cho, Phyu P Aung, Carlos A Torres-Cabala, Victor G Prieto, and Jonathan L Curry
Mechanisms of dermatologic toxicities to immune checkpoint inhibitor cancer therapies., Riyad N H Seervai, Avilasha Sinha, and Rajan P Kulkarni
Lisocabtagene maraleucel as second-line therapy in adults with relapsed or refractory large B-cell lymphoma who were not intended for haematopoietic stem cell transplantation (PILOT): an open-label, phase 2 study., Alison Sehgal, Daanish Hoda, Peter A Riedell, Nilanjan Ghosh, Mehdi Hamadani, Gerhard C Hildebrandt, John E Godwin, Patrick M Reagan, Nina Wagner-Johnston, James Essell, Rajneesh Nath, Scott R Solomon, Rebecca Champion, Edward Licitra, Suzanne Fanning, Neel Gupta, Ronald Dubowy, Aleco D'Andrea, Lei Wang, Ken Ogasawara, Jerill Thorpe, and Leo I Gordon
Emergency Severity Index Comparisons Among Race. Podium talk presented at Providence Management Report, 2022, Portland, OR., D Selander and ST Chin
Clinical Trial Participation and COVID-19: a Descriptive Analysis from the American Heart Association's Get With The Guidelines Registry., Kevin S Shah, Adriana E Reyes-Miranda, Steven M Bradley, Khadijah Breathett, Sandeep R Das, Tyler J Gluckman, Divya Gupta, Daniel T Leung, R Kannan Mutharasan, Pamela N Peterson, Emily S Spivak, and Rashmee U Shah
Clinical Trial Participation and COVID-19: a Descriptive Analysis from the American Heart Association's Get With The Guidelines Registry., Kevin S Shah, Adriana E Reyes-Miranda, Steven M Bradley, Khadijah Breathett, Sandeep R Das, Tyler J Gluckman, Divya Gupta, Daniel T Leung, R Kannan Mutharasan, Pamela N Peterson, Emily S Spivak, and Rashmee U Shah
772 A phase 1/2 dose escalation/expansion study evaluating the safety, pharmacokinetics, pharmacodynamics, and antitumor activity of E-602, a bi-sialidase fusion protein, in advanced cancer (GLIMMER-01), Manish Sharma, Brendan Curti, and See all authors in comments
Immunotherapy in head and neck squamous cell carcinoma: a narrative review., Shay Sharon and R Bryan Bell
Inhaled anaesthesia and analgesia contribute to climate change., Jodi D Sherman and Brian B. Chesebro
Comparison of Exparel with Other Analgesic Medication for the Traumatic Rib Fracture: A Retrospective Study, K Shrestha, HF Li, and See all authors in comments
Amivantamab and lazertinib in patients with EGFR-mutant non–small cell lung (NSCLC) after progression on osimertinib and platinum-based chemotherapy: Updated results from CHRYSALIS-2., Catherine A. Shu, Rachel E Sanborn, and See full list of authors in comments
Contemporary, national patterns of surgery after preoperative therapy for stage II/III rectal adenocarcinoma., Celine Soriano, Henry T Bahnson, Jennifer A Kaplan, Bruce Lin, Ravi Moonka, Huong T Pham, Hagen F Kennecke, and Vlad Simianu
Registry Data Show Complication Rates and Cost in Revision Hip Arthroplasty, R Southgate, HF Li, Genevieve Rollier, and See all authors in comments
Use of Novel Strategies to Develop Guidelines for Management of Pyogenic Osteomyelitis in Adults: A WikiGuidelines Group Consensus Statement., Brad Spellberg, Gloria Aggrey, Meghan B Brennan, Brent Footer, Graeme Forrest, Fergus Hamilton, Emi Minejima, Jessica Moore, Jaimo Ahn, Michael Angarone, Robert M Centor, Kartikeya Cherabuddi, Jennifer Curran, Kusha Davar, Joshua Davis, Mei Qin Dong, Bassam Ghanem, Doug Hutcheon, Philipp Jent, Minji Kang, Rachael Lee, Emily G McDonald, Andrew M Morris, Rebecca Reece, Ilan S Schwartz, Miranda So, Steven Tong, Christopher Tucker, Noah Wald-Dickler, Erica J Weinstein, Riley Williams, Christina Yen, Shiwei Zhou, Todd C Lee, and WikiGuidelines Group
Preoperative Risk Prediction for Pancreatectomy: A Comparative Analysis of Three Scoring Systems., Holly Spitzer, Ryan Yang, Phillip Kemp Bohan, Shu-Ching Chang, Gary Grunkemeier, Timothy Vreeland, and Daniel W Nelson
Systemic therapy strategies in triple negative breast cancer, S Stanton
549 Booster vaccination of a HER2 helper T-cell vaccine increased HER2 immunity in metastatic HER2 positive breast cancer., Sasha Stanton, Jennifer Childs, Doreen Higgins, Angela Kask, Yi Yang, and Mary Disis
Phase I trial of the safety and immunogenicity of a tri-antigen vaccine targeting HER2, IGFBP-2, and IGF-IR in patients with non-metastatic breast cancer, Sasha E. Stanton and See all authors in comments
Neoadjuvant survivin-targeted immunotherapy maveropepimut-S (MVP-S) to increase Th1 immune response in Ki67-high hormone receptor-positive (HR+) early-stage breast cancer (ESBC)., Sasha Stanton, Lisa Diana MacDonald, Staci Mellinger, Nikki Moxon, Tracy L. Kelly, Heather Ann Hirsch, Stephan Fiset, Kristina H Young, and David B Page
646 Neoadjuvant immunotherapy combining maveropepimut-S (MVP-S) with letrozole decreases Ki67 and increases Th1 immune response in hormone receptor positive (HR+) early-stage breast cancer (ESBC), Sasha Stanton, David Page, Kristina Young, and See all authors in comments
Abstract PR007: Candidate antigens for a ductal carcinoma in situ vaccine, essential for breast cancer cell survival across multiple subtypes, are immunogenic in DCIS and IBC, Sasha Stanton, Jason Schlumbohm, and Mary L. Disis
Neoadjuvant survivin-targeted immunotherapy maveropepimut-S (MVP-S) to increase Th1 immune response in Ki67-high hormone receptor-positive (HR+) early-stage breast cancer (ESBC), Sasha Stanton and See all authors in comments
Phase I trial of the safety and immunogenicity of a tri-antigen vaccine targeting HER2, IGFBP-2, and IGF-IR in patients with non-metastatic breast cancer, Sasha Stanton and See all authors in comments
3380 / 8 - Seven autoantibody panel, validated in two independent patient serum collections, can detect women with DCIS and invasive breast cancer, Sasha Stanton and See full list of authors in comments
Neoadjuvant survivin-targeted immunotherapy maveropepimut-S (MVP-S) to increase Th1 immune response in Ki67-high hormone receptor-positive (HR+) early-stage breast cancer (ESBC)., Sasha Stanton, Kristina H Young, David B Page, and See all authors in comments
Immunology 101, SE Stanton
647 Phase I studies of AgenT-797, a novel allogeneic invariant natural killer T (iNKT) cell therapy, for the treatment of patients with solid tumors or multiple myeloma, Don Stevens, Rachel Sanborn, and See all authors in comments
Characterizing 30-Day Postoperative Acute Care Visits: A National Surgical Quality Improvement Program Collaborative Analysis., Ashley L Sweet, Thomas L Sutton, Krista A Curtis, Nathan Knapp, Brett C Sheppard, and Karen A Zink
Grace Under Pressure., Nancy K Sweitzer, Daniel Burkhoff, Sophia Airhart, and James C Fang
Health-related quality-of-life analyses from a multicenter, randomized, double-blind phase 2 study of patients with differentiated thyroid cancer treated with lenvatinib 18 or 24 mg/day., Matthew H. Taylor, Sophie Leboulleux, Yury Panaseykin, Bhavana Konda, Christelle de La Fouchardiere, Brett G M Hughes, Andrew G Gianoukakis, Young Joo Park, Ilia Romanov, Monika K Krzyzanowska, Diana Garbinsky, Bintu Sherif, Jie Janice Pan, Terri A Binder, Nicholas Sauter, Ran Xie, and Marcia S Brose
IO in Thyroid Cancer, Michael Taylor
Academy of Nutrition and Dietetics: Revised 2022 Standards of Practice and Standards of Professional Performance for Registered Dietitian Nutritionists (Competent, Proficient, and Expert) in Adult Weight Management., Colleen Tewksbury, Robin Nwankwo, and Janet Peterson
TP022/#1424 A phase I/II study evaluating intraperitoneal GEN-1 in combination with neoadjuvant chemotherapy in patients newly diagnosed with advanced epithelial ovarian cancer, Premal Thaker, Melanie Bergman, and See all authors in comments
409 Manufacturing of a clinical scale CD8 TIL product, AGX148, with and without gene silencing of PD-1 using self-delivering RNAi INTASYLTM PH-762, Colin Thalhofer, Tarsem Moudgil, Bernard A Fox, Nelson Sanjuan Silva, Eric Tran, and See all authors in comments
Enriching for tumor-reactive CD8 TIL (AGX148) leads to effective tumor clearance in a patient-derived xenograft model, C Thalhofer, Andrew D Weinberg, and See full list of authors in comments
Association of PD-L1 expression, tumor mutational burden and immunotherapy with venous thrombosis in patients with solid organ malignancies., Rajat Thawani, Thomas Kartika, Benjamin Elstrott, Elizabeth Batiuk, Derrick L Tao, Sonia Gowda, Lilian Chen, Corinne Lavasseur, Nattapron Tun, Nicholas F Taflin, and Joseph Shatzel
Defining Baseline and Maximum Stages of Cardiogenic Shock Severity: Insights from the Cardiogenic Shock Working Group, K Thayer, Jacob Abraham, and See all authors in comments
Robotic Versus Manual Total Knee Arthroplasty in High Volume Surgeons: A Comparison of Cost and Quality Metrics., Geoffrey S Tompkins, Katie Sypher, Hsin-Fang Li, T Michael Griffin, and Paul J Duwelius
Circulating Tumor DNA Identifies Diverse Landscape of Acquired Resistance to Anti-Epidermal Growth Factor Receptor Therapy in Metastatic Colorectal Cancer., James T Topham, Chris J O'Callaghan, Harriet Feilotter, Hagen F Kennecke, Young S Lee, Weimin Li, Kimberly C Banks, Katie Quinn, Daniel J Renouf, Derek J Jonker, Dongsheng Tu, Eric X Chen, and Jonathan M Loree
Cell transfer therapy targeting mutated neoantigens in epithelial cancer, E Tran
Targeting mutant KRAS with adoptive T-cell therapy, E Tran
Targeting mutant KRAS with TCR-gene therapy, E Tran
TCR-gene therapy targeting mutant KRAS, E Tran
Targeting mutant KRAS with TCR-gene therapy, Eric Tran
TILs Update, Eric Tran
Neoantigen T-Cell Receptor Gene Therapy in Pancreatic Cancer. Reply., Eric Tran, Walter Urba, and Rom Leidner
The Impact of Remote Optimization of Guideline-Directed Medical Therapy in Patients with NYHA Stage II and III Heart Failure, MN Tran, Jacob Abraham, and See all authors in comments
A Health Care System's Approach to Support Nursing Leaders in Mitigating Burnout Amid a COVID-19 World Pandemic., Sylvain Trepanier, Robin Henderson, and Arpan Waghray
A Health Care System's Approach to Support Nursing Leaders in Mitigating Burnout Amid a COVID-19 World Pandemic., Sylvain Trepanier, Robin Henderson, and Arpan Waghray
Eight-year outcomes of aortic valve replacement with the Carpentier-Edwards PERIMOUNT Magna Ease valve., Steven Tsui, Michael Rosenbloom, James Abel, Jeffrey Swanson, Axel Haverich, Joseph Zacharias, Gilbert Schorlemmer, Gideon Cohen, Michael Moulton, and Rüdiger Lange
Evolution of TCAR in my carotid practice: patient selection, learning curve, and lessons learned, Brant Ullery
Role of protocolization in the management of acute aortic syndromes, Brant Ullery
Editorial: Mechanisms of Lymphocyte Exclusion in the Tumor Microenvironment., Rieneke van de Ven, Carlo Bifulco, Jason J Luke, and Sarah E Church
Patient-Reported Outcomes for Fully Vaccinated COVID-19 Patients Over 6 Weeks: The Experiences of Clinical Breakthrough Cases., Keri B Vartanian, Daniel Fish, Benjamin Gronowski, Natalie Royal Kenton, and Ari Robicsek
Patient experience and healthcare utilization for a COVID-19 telemedicine home monitoring program offered in English and Spanish., Keri B Vartanian, Megan Holtorf, Emily J Cox, George Diaz, Hargobind Khurana, Sherene Schlegel, Caroline Raganit, Brandon Ong, and Todd Czartoski
Neoantigen-specific CD4 + T cells in human melanoma have diverse differentiation states and correlate with CD8 + T cell, macrophage, and B cell function, Joshua R Veatch, Sylvia M Lee, Carolyn Shasha, Naina Singhi, Julia L Szeto, Ata S Moshiri, Teresa S Kim, Kimberly Smythe, Paul Kong, Matthew Fitzgibbon, Brenda Jesernig, Shailender Bhatia, Scott S Tykodi, Evan T Hall, David R Byrd, John A Thompson, Venu G Pillarisetty, Thomas Duhen, A McGarry Houghton, Evan Newell, Raphael Gottardo, and Stanley R Riddell
Single-access for Impella-supported percutaneous coronary intervention using a sheathless technique with an 8 Fr guide., Louis Verreault-Julien, Nikoloz Shekiladze, Jason Wollmuth, and Stéphane Rinfret
