Submissions from 2022
Cancer Vaccines: A Phoenix Rising from the Ashes, Bernard Fox
Combining 10x scRNA-seq and 100 plex mIF: Too much data or complimentary technologies to examine what works, Bernard Fox
Complex Cancer Vaccines: An Approach to Induce Immunity Against Gastroesophageal Malignancies in 2022, Bernard Fox
Comprehensive Spatial Phenotyping: Mapping the Tumor Microenvironment at Scale, Bernard Fox
Immune Activating and Cancer Vaccine Technology, Bernard Fox
Overview of Immunotherapy and Challenges for Immuno-Oncology, Bernard Fox
Recommended phase 2 dose (RP2D) of HB-200 arenavirus-based cancer immunotherapies in patients with HPV16+ cancers., Siqing Fu, Rom Leidner, and Matthew H Taylor
Functional status at 30 and 90 days after mild ischaemic stroke., Hannah Gardener, Leo A Romano, Eric E Smith, Iszet Campo-Bustillo, Yosef Khan, Sofie Tai, Nikesha Riley, Ralph L Sacco, Pooja Khatri, Heather M Alger, Brian Mac Grory, Deepak Gulati, Navdeep S Sangha, Karin E Olds, Curtis G Benesch, Adam G Kelly, Scott S Brehaut, Amit Kansara, Lee H Schwamm, and Jose G Romano
Management of Anorectal Malformations and Hirschsprung Disease., Colin D Gause and Sanjay Krishnaswami
Video game rehabilitation for outpatient stroke (VIGoROUS): A multi-site randomized controlled trial of in-home, self-managed, upper-extremity therapy., Lynne V Gauthier, Deborah S Nichols-Larsen, Gitendra Uswatte, Nancy Strahl, Marie Simeo, Rachel Proffitt, Kristina Kelly, Roger Crawfis, Edward Taub, David Morris, Linda Pax Lowes, Victor Mark, and Alexandra Borstad
A Phase 1 Study of TAK-676, a Novel STING Agonist, Plus Pembrolizumab Following Radiation Therapy in Patients with Advanced Non–Small-Cell Lung Cancer (NSCLC), Triple-Negative Breast Cancer (TNBC), or Squamous-Cell Carcinoma of the Head and Neck (SCCHN), NK Gerber, DB Page, and See all authors in comments
A phase 2 study of an off-the-shelf, multi-neoantigen vector (ADXS-503) in patients with metastatic non–small cell lung cancer either progressing on prior pembrolizumab or in the first-line setting., Gregory James Gerstner, Rachel E Sanborn, and See full list of authors in comments
Safety Analyses of NRG BR004: A Randomized, Double-blind, Phase III Trial of Taxane/Trastuzumab/Pertuzumab with Atezolizumab or Placebo in First-line HER2-Postive Metastatic Breast Cancer (MBC), CE Geyer and DB Page
Safety of Nivolumab Added to Chemoradiation Therapy Platforms for Intermediate and High-Risk Locoregionally Advanced Head and Neck Squamous Cell Carcinoma: Radiation Therapy Oncology Group Foundation 3504., Maura L Gillison, Robert L Ferris, Jonathan Harris, A Dimitrios Colevas, Loren K Mell, Christina Kong, Richard C Jordan, Kevin L Moore, Minh-Tam Truong, Claudia Kirsch, Arnab Chakravarti, Dukagjin M Blakaj, David A Clump, James P Ohr, John F Deeken, Michael F Gensheimer, Nabil F Saba, Jennifer A Dorth, David I Rosenthal, Rom S Leidner, Randall J Kimple, Mitchell Machtay, Walter J Curran, Pedro Torres-Saavedra, and Quynh Thu Le
Housing and Reentry: A Mixed-Method Evaluation of a Low-Cost Community-Based Intervention for Increasing Access to Housing Post-Incarceration, Monique Gill, Kyle Jones, Ritu Ghosal, James M. Scanlan, and Emily J. Cox
Accelerating Cardiovascular Outcomes/Health Services Research Within Community-Based Health Systems-Lessons Learned and Steps Moving Forward, Ty J. Gluckman
Accelerating Cardiovascular Outcomes/Health Services Research Within Community-Based Health Systems-Lessons Learned and Steps Moving Forward, Ty J. Gluckman
Acute, Near-Term, and Long-Term Cardiovascular Sequelae of COVID-19, Ty J. Gluckman
Benefit and Barriers to New Quality Measures, Ty J. Gluckman
Cardiovascular Sequelae of COVID-19, Ty J. Gluckman
Cardiovascular Sequelae of COVID-19, Ty J. Gluckman
Cardiovascular Sequelae of COVID-19 in Adults: Myocarditis, Long COVID, and Return to Play, Ty J. Gluckman
Cost of Prevention—How Much is Too Much?, Ty J. Gluckman
Diversifying Patients in Clinical Trials--Approaches to Different Trial Designs, Ty J. Gluckman
Intersection of Antiplatelet and Anticoagulant Therapy-What to Do When a Patient Needs Both, Ty J. Gluckman
Ongoing Dilemmas with Surveillance and Diagnosis of Atrial Fibrillation, Ty J. Gluckman
Prevention and Treatment of COVID-19: A Review of the Current Data, Ty J. Gluckman
Referral to Advanced Heart Failure-A Key Component in Team-Based Care, Ty J. Gluckman
Target: Aortic Stenosis—Initiative Experience, Ty J. Gluckman
Treadmill, Nuclear Myocardial Perfusion Imaging (MPI), and Cardiac PET, Ty J. Gluckman
Stakeholder Perspectives - Clinical Care, Ty J. Gluckman, J Bachmann, H Chetan, ATS Sandhu, and C Porter
Accelerating Cardiovascular Outcomes/Health Services Research Within Community-Based Health Systems-Lessons Learned and Steps Moving Forward, Tyler J Gluckman
Accelerating Cardiovascular Outcomes/Health Services Research Within Community-Based Health Systems-Lessons Learned and Steps Moving Forward, Tyler J Gluckman
Accelerating Cardiovascular Outcomes/Health Services Research Within Community-Based Health Systems-Lessons Learned and Steps Moving Forward, Tyler J Gluckman
Cardiovascular Sequelae of COVID-19, Tyler J Gluckman
Cost of Prevention—How Much is Too much?, Tyler J Gluckman
Do Registries Help Us or Cost Us, Tyler J Gluckman
Incorporating the 2021 AHA/ACC Chest Pain Guidelines Into My Clinical Practice, Tyler J Gluckman
Optimizing LDL-C: Individualizing Treatment Using Statins and Nonstatin Therapy, Tyler J Gluckman
Prevention and Treatment of COVID-19: A Review of the Current Data, Tyler J Gluckman
Treadmill, Nuclear Myocardial Perfusion Imaging (MPI), and Cardiac PET, Tyler J Gluckman
ACC Expert Consensus Decision Pathway of Bleeding Management in Patients on Oral Anticoagulant and Cost Implications, Tyler J Gluckman and See full list of authors in comments
Polyunsaturated fatty acids, omega-3 fatty acids, and eicosapentaenoic acid- mechanisms of action, Tyler J Gluckman and See full list of authors in comments
A phase 1b, multicenter, dose-escalation study of subasumstat (TAK-981) in combination with pembrolizumab in patients (pts) with advanced solid tumors., Sanjay Goel, Rachel E Sanborn, and See full list of authors in comments
Safety and tolerability of MEDI0562, an OX40 agonist monoclonal antibody, in combination with durvalumab or tremelimumab in adult patients with advanced solid tumors., Jonathan W Goldman, Sarina A Piha-Paul, Brendan Curti, Katrina S Pedersen, Todd M Bauer, Stefanie L Groenland, Richard D Carvajal, Vaishali Chhaya, Gray Kirby, Kelly McGlinchey, Scott A Hammond, Katie L Streicher, Danielle Townsley, Young Kwang Chae, Jens Voortman, Aurelien Marabelle, and John Powderly
The Development and Dynamics of Pre-existing immunity in tumors, Michael Gough
Fluorescence tagging to monitor CD8 T cell recirculation from the tumor to the tumor-draining lymph node: the impact of focal radiation therapy on recirculation, Michael J. Gough
Tumor resident memory CD8 T cell formation and concomitant tumor immunity is CD40L dependent and CD4 independent, Michael J. Gough
The paradox of radiation and T cells in tumors., Michael J. Gough and Marka R Crittenden
Tumor resident memory CD8 T cell formation and concomitant tumor immunity is CD40L dependent and CD4 independent., Michael J. Gough, Thomas Duhen, Marka R Crittenden, and See all authors in comments
Differences in access to virtual and in-person primary care by race/ethnicity and community social vulnerability among adults diagnosed with COVID-19 in a large, multi-state health system., Diana J Govier, Hannah Cohen-Cline, Katherine Marsi, and Sarah E Roth
Leveraging Healthcare System Data to Identify High-Risk Dyslipidemia Patients., Nayrana Griffith, Grace Bigham, Aparna Sajja, and Ty J Gluckman
Reproductive Health Features Associated with SCAD: A Report of the iSCAD Registry, A Grodzinsky, L Tam, and See all authors in comments
The Role of Community Health Workers in Developing Multidimensional Organizational Relationships., Benjamin Gronowski, Sarah E Roth, Tanisha Tate Woodson, Hannah Cohen-Cline, and Natalie Royal Kenton
Durability of B and T cell responses against a spike protein of SARS-CoV2 elicited by mRNA vaccines, LT Hamilton, Bernard A Fox, William L. Redmond, Brian D. Piening, and See full list of authors in comments
Intratumoral Electroporation of Plasmid Encoded IL12 and Membrane-Anchored Anti-CD3 Increases Systemic Tumor Immunity., Mia Han, Bianca Nguyen, Jack Y Lee, Erica Browning, Jun Zhang, Anandaroop Mukhopadhyay, Ravindra Gujar, Jon Salazar, Reneta Hermiz, Lauren Svenson, Annah S Rolig, William L. Redmond, Alain P Algazi, Adil I Daud, David A Canton, and Christopher G Twitty
Assessment of Regional Variability in COVID-19 Outcomes Among Patients With Cancer in the United States., Jessica E Hawley, Tianyi Sun, David D Chism, Narjust Duma, Julie C Fu, Na Tosha N Gatson, Sanjay Mishra, Ryan H Nguyen, Sonya A Reid, Oscar K Serrano, Sunny R K Singh, Neeta K Venepalli, Ziad Bakouny, Babar Bashir, Mehmet A Bilen, Paolo F Caimi, Toni K Choueiri, Scott J Dawsey, Leslie A Fecher, Daniel B Flora, Christopher R Friese, Michael J Glover, Cyndi J Gonzalez, Sharad Goyal, Thorvardur R Halfdanarson, Dawn L Hershman, Hina Khan, Chris Labaki, Mark A Lewis, Rana R McKay, Ian Messing, Nathan A Pennell, Matthew Puc, Deepak Ravindranathan, Terence D Rhodes, Andrea V Rivera, John Roller, Gary K Schwartz, Sumit A Shah, Justin A Shaya, Mitrianna Streckfuss, Michael A Thompson, Elizabeth M Wulff-Burchfield, Zhuoer Xie, Peter Paul Yu, Jeremy L Warner, Dimpy P Shah, Benjamin French, Clara Hwang, COVID-19 and Cancer Consortium (CCC19), and Hagen F Kennecke (COVID-19 and Cancer Consortium (CCC19))
Clinical Presentation and In-Hospital Trajectory of Heart Failure and Cardiogenic Shock., Jaime Hernandez-Montfort, Manreet Kanwar, Shashank S Sinha, A Reshad Garan, Vanessa Blumer, Rachna Kataria, Evan H Whitehead, Michael Yin, Borui Li, Yijing Zhang, Katherine L Thayer, Paulina Baca, Fatou Dieng, Neil M Harwani, Maya Guglin, Jacob Abraham, Gavin Hickey, Sandeep Nathan, Detlef Wencker, Shelley Hall, Andrew Schwartzman, Wissam Khalife, Song Li, Claudius Mahr, Ju Kim, Esther Vorovich, Mohit Pahuja, Daniel Burkhoff, and Navin K Kapur
Frequency of survival to hospital discharge after cardiopulmonary resuscitation on FOX TV's The Resident., Diana Herrera-Perez, Jennifer Gill, Alyson Haslam, Tyler Crain, Quiana Klossner, and Vinay Prasad
Heart Only Transplant Program Start-Up in the COVID Pandemic: Challenges and Unexpected Opportunities, P Higby, K Koomalsingh, and J Gelow
5 Development of a vaccine to intercept oral cancer, Traci Hilton, Tarsem Moudgil, Richard Bryan Bell, and See all authors in comments
Creation of an RN Data Coordinator Role in a New Heart Transplant Program Results in Improved Data Integrity and Timeliness and Promotes Program Improvement Through Tracking of Quality and Performance Metrics, M Hite, S Verburg, J Gelow, and P Higby
Creation of an RN data coordinator role in a new heart transplant program results in improved data integrity and timeliness and promotes program improvement through tracking of quality and performance metrics., M Hite, S Verburg, Jill M Gelow, and P Higby
Gasping for Air: Embedded COPD Decision Support Improves Guideline Adherence, G Hocum, L Wang, M Modi, and SS Sanders
Abnormal response after multiple rapid swallow provocation is not predictive of post-operative dysphagia following a tailored fundoplication approach., Maggie M Hodges, Melissa L DeSouza, Kevin M Reavis, Daniel Davila Bradley, and Christy M Dunst
731 A first-in-human trial of an integrin beta-6 targeted antibody-drug conjugate (ADC), SGN-B6A, in patients with advanced solid tumors: interim results of a phase 1 study (SGNB6A-001), Antoine Hollebecque, Rachel E Sanborn, and See full list of authors in comments
Building with a Blueprint: Taking a Patient Centered Specialty Practice from Medical Neighborhood to High Performing Network, X Huang and D Christensen
Population Health: Turning In-Basket Into ROI, X Huang and L Jones Larson
The job market for HPB surgeons: leadership perspectives on surgeon skillsets, training pathways, and hiring., Dorothy Hughes, Fernanda Romero Hernandez, Phoebe Miller, Susanne Warner, Michele Babicky, Brendan Visser, Adnan Alseidi, and AHPBA SWOT Taskforce
Potential Impact of 2017 American College of Cardiology/American Heart Association Hypertension Guideline on Contemporary Practice: A Cross-Sectional Analysis From NCDR PINNACLE Registry., Aliza Hussain, Salim S Virani, Luke Zheng, Tyler J Gluckman, William B Borden, Frederick A Masoudi, and Thomas M Maddox
8 Universal LCMS-based assay platform, refmAb-Q nSMOL, for monitoring monoclonal antibody therapeutics using one reference antibody, Noriko Iawmoto, Yoshinobu Koguchi, Kotoko Yokoyama, Akinobu Hamada, Atsushi Yonezawa, Brian Piening, Eric Tran, Bernard Fox, William Redmond, and Takashi Shimada
Perceived utility of electrodiagnostic testing in critical illness myopathy and polyneuropathy: A survey of intensive care unit providers., Michael Isfort, Bryan J McVerry, Lori Shutter, Minji Kim, and David Lacomis
Proteogenomic Characterization of Head and Neck Squamous Cell Cancer Immunopeptidomes to Detect Non Canonical Protein Targets for Cancer Immunotherapy., N Iwamoto, Richard Bryan Bell, Carlo Bifulco, Walter Urba, Rom Leidner, Brian D. Piening, Bernard A Fox, and See full author list in comments
A rapid and universal liquid chromatograph-mass spectrometry-based platform, refmAb-Q nSMOL, for monitoring monoclonal antibody therapeutics., Noriko Iwamoto, Yoshinobu Koguchi, Kotoko Yokoyama, Akinobu Hamada, Atsushi Yonezawa, Brian D Piening, Eric Tran, Bernard A Fox, William L Redmond, and Takashi Shimada
Uncovering the dark immunopeptidome of head and neck squamous cell carcinoma (HNSCC): relevance for universal cancer vaccines, immunological monitoring and TIL therapy, Noriko Iwamoto, Takashi Shimada, Tarsem Moudgil, Ryan Meng, Tanisha Christie, Alexa Dowdell, Rom Leidner, Bryan Bell, William Redmond, Eric Tran, Hong-Ming Hu, Traci Hilton, Brian Piening, Yoshinobu Koguchi, and Bernard Fox
In mild acute diverticulitis, outpatient therapy without antibiotics was noninferior to antibiotics., Meera Jain and Amy Dechet
Mid-pregnancy immune dysregulation and its association with maternal metabolic and genetic factors in those with preterm birth: Insights using artificial intelligence., L Jelliffe-Pawlowski, Brian D. Piening, and See full list of authors in comments
Evaluation of long-term anti-Spike immune response following a novel coronavirus vaccine (CORVax): electroporation of SARS-CoV-2 Spike plasmid DNA plus plasmid IL-12, SM Jensen, Bernard A Fox, and See full list of authors in comments
Assessing Barriers to Consistent Adult Congenital Heart Disease Care: When in Doubt, Ask the Patient, R Jin
Comparison of 26-mm Evolut and 23-mm Sapien 3 Valves in TAVR for Small Aortic Annulus., Ruyun Jin, Emily J Cox, Branden Reynolds, Brydan Curtis, Robert W. Hodson, Michael Reed, Sameer Gafoor, Gary Grunkemeier, Matthew Forrester, and Michael Ring
The CUSUM Slope Equals Observed Minus Expected Mortality and Can Be Visualized by a "Slope-Meter"., Ruyun Jin, Mansen Wang, Lian Wang, and Gary Grunkemeier
Interim results of an ongoing phase 1/2a study of HPN328, a tri-specific, half-life extended, DLL3-targeting, T-cell engager, in patients with small cell lung cancer and other neuroendocrine cancers., Melissa Lynne Johnson, Rachel E Sanborn, and See full list of authors in comments
The short of breath and sweaty principle: Risk reduction therapies available to everyone, Shelly J. Johnson and Miles Hassell
The Birth of Tragedy? Extremely Premature Births and Shared Decision-Making., Joseph Kaempf and Kevin M. Dirksen
The Triple Aim Quality Improvement Gold Standard Illustrated as Extremely Premature Infant Care., J W Kaempf, Lian Wang, and Michael Stephen Dunn
PCM1-JAK2 Fusion Tyrosine Kinase Gene-Related Neoplasia: A Systematic Review of the Clinical Literature., Henry G Kaplan, Ruyun Jin, Carlo Bifulco, James M Scanlan, and David R Corwin
Reszinate—A Phase 1/2 Randomized Clinical Trial of Zinc and Resveratrol Utilizing Home Patient-Obtained Nasal and Saliva Viral Sampling, Henry Kaplan, Kai Wang, Kimberly M. Reeves, James Scanlan, Christopher C. Nunn, Douglas A. Kieper, Joshua L. Mark, Inyoul Lee, Rachel Liu, Ruyun Jin, Michael J. Bolton, and Jason D. Goldman
Criteria for Defining Stages of Cardiogenic Shock Severity., Navin K Kapur, Manreet Kanwar, Shashank S Sinha, Katherine L Thayer, A Reshad Garan, Jaime Hernandez-Montfort, Yijing Zhang, Borui Li, Paulina Baca, Fatou Dieng, Neil M Harwani, Jacob Abraham, Gavin Hickey, Sandeep Nathan, Detlef Wencker, Shelley Hall, Andrew Schwartzman, Wissam Khalife, Song Li, Claudius Mahr, Ju H Kim, Esther Vorovich, Evan H Whitehead, Vanessa Blumer, and Daniel Burkhoff
Intermittent Occlusion of the Superior Vena Cava to Improve Hemodynamics in Patients With Acutely Decompensated Heart Failure: The VENUS-HF Early Feasibility Study., Navin K Kapur, Michael S Kiernan, Irakli Gorgoshvili, Rayan Yousefzai, Esther E Vorovich, Ryan J Tedford, Andrew J Sauer, Jacob Abraham, Charles D Resor, Carey D Kimmelstiel, Keith H Benzuly, Daniel H Steinberg, Julie Messer, Daniel Burkhoff, and Richard H Karas
Single Acute Mechanical Circulatory Support Device Use is Associated with Reduced Mortality Compared to Multi-Agent Drug Therapy Alone for Cardiogenic Shock: An Analysis of the Cardiogenic Shock Working Group Registry, NK Kapur, Jacob Abraham, and See all authors in comments
Single Acute Mechanical Circulatory Support Device Use is Associated with Reduced Mortality Compared to Multi-Agent Drug Therapy Alone for Cardiogenic Shock: An Analysis of the Cardiogenic Shock Working Group Registry, NK Kapur, B Li, Y Zhang, K Thayer, A Garan, J Hernandez-Montfort, M Kanwar, SS Sinha, C Mahr, and Jacob Abraham
A Case Report: Splenium of the Corpus Callosum Infarct Associated With COVID-19., David A Karp, Gabriel Beaudoin, and Robert A Egan
Higher Utilization of Drugs and Devices, including ECMO, in Patients Presenting with Cardiogenic Shock Due to De Novo Heart Failure Compared with Acute on Chronic Heart Failure, R Kataria, Jacob Abraham, and See all authors in comments
Umbilical cord milking in nonvigorous infants: a cluster-randomized crossover trial., Anup C Katheria, Erin Clark, Bradley Yoder, Georg M Schmölzer, Brenda Hiu Yan Law, Walid El-Naggar, David Rittenberg, Sheetal Sheth, Mohamed A Mohamed, Courtney Martin, Farha Vora, Satyan Lakshminrusimha, Mark Underwood, Jan Mazela, Joseph Kaempf, Mark Tomlinson, Yvonne Gollin, Kevin Fulford, Yvonne Goff, Paul Wozniak, Katherine Baker, Wade Rich, Ana Morales, Michael Varner, Debra Poeltler, Yvonne Vaucher, Judith Mercer, Neil Finer, Laure El Ghormli, Madeline Murguia Rice, and Milking In Nonvigorous Infants group
Ex vivo analysis of radiation effects on tumor infiltrating immune cells using tumor explants, Aanchal Preet Kaur, Gwen Kramer, Marka R. Crittenden, and Michael J. Gough
Ex vivo tumor explant analyses reveal suppression of tumor-infiltrating T cells, but not myeloid cells, post radiation treatment, AP Kaur, G Kramer, MR Crittenden, and MJ Gough
