Submissions from 2022
940 siRNA screen of upregulated genes identifies targets for a multiantigen polyepitope vaccine to prevent HNSCC, Fnu Alka, James Annis, Brady Bernard, and Sasha Stanton
Factors Associated with a Complicated Hospital Course in Patients with Spontaneous Coronary Artery Dissection: A Report of the iSCAD Registry, F Alkhalfan, L Tam, and See all authors in comments
Transcarotid Access is Preferred to Transaxillary Access for Nonfemoral TAVR., Keith Allen, Adnan Chhatriwalla, and Eric B Kirker
Gut microbiota analyses of Saudi populations for type 2 diabetes-related phenotypes reveals significant association., Fahad A Al-Muhanna, Alexa K Dowdell, Abdulmohsen H Al Eleq, Waleed I Albaker, Andrew W Brooks, Ali I Al-Sultan, Abdullah M Al-Rubaish, Khaled R Alkharsah, Raed M Sulaiman, Abdulaziz A Al-Quorain, Cyril Cyrus, Rudaynah A Alali, Chittibabu Vatte, Fred L Robinson, Xin Zhou, Michael P Snyder, Afnan F Almuhanna, Brendan J Keating, Brian D. Piening, and Amein K Al-Ali
Penicillin allergy that persisted after 66 years: case report., Evon Anukam and Jenny Zhu
Are angiotensin-converting enzyme inhibitors/angiotensin receptor blockers associated with reduced severe acute respiratory syndrome coronavirus 2 infections and improved outcomes, and does race matter?, John Armato, Ralph A DeFronzo, Shih-Ting Chiu, Deanna Rider, and Ronald Ruby
Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 2nd - 4th, 2021, Italy)., Paolo A Ascierto, Sanjiv S Agarwala, Christian Blank, Corrado Caracò, Richard D Carvajal, Marc S Ernstoff, Soldano Ferrone, Bernard A Fox, Thomas F Gajewski, Claus Garbe, Jean-Jacques Grob, Omid Hamid, Michelle Krogsgaard, Roger S Lo, Amanda W Lund, Gabriele Madonna, Olivier Michielin, Bart Neyns, Iman Osman, Solange Peters, Poulikos I Poulikakos, Sergio A Quezada, Bradley Reinfeld, Laurence Zitvogel, Igor Puzanov, and Magdalena Thurin
Perspectives in Immunotherapy: meeting report from the Immunotherapy Bridge, December 1st-2nd, 2021., Paolo A Ascierto, Antonio Avallone, Nina Bhardwaj, Carlo Bifulco, Sergio Bracarda, Joshua D Brody, Luigi Buonaguro, Sandra Demaria, Leisha A Emens, Robert L Ferris, Jérôme Galon, Samir N Khleif, Christopher A Klebanoff, Tamara Laskowski, Ignacio Melero, Chrystal M Paulos, Sandro Pignata, Marco Ruella, Inge Marie Svane, Janis M Taube, Bernard A Fox, Patrick Hwu, and Igor Puzanov
The "Great Debate" at Immunotherapy Bridge 2021, December 1st-2nd, 2021., Paolo A Ascierto, Lisa H Butterfield, Olivera J Finn, Andrew Futreal, Omid Hamid, Theresa LaVallee, Michael A Postow, Igor Puzanov, Jeffrey Sosman, Bernard A Fox, and Patrick Hwu
ENPP1 limits efficacy of radiation therapy in a murine pancreatic cancer model, J Baird, A Alice, M Ball, G Kramer, T Blair, A Kaur, M Gough, and M Crittenden
Clinical actionability and therapy selection for advanced NSCLC patients tested using comprehensive genomic profiling, B Bapat, R Weerasignhe, R Meng, A Dowdell, SC Chang, B Schroeder, C Bifulco, and B Piening
NIRT – Not Just Neoadjuvant IO, R Bryan Bell
Novel Tool Used for Measuring Team Resilience Among Caregivers in a Hospital Setting: Resilient Team Traits Identified, Tiara Benson, Ma Fe Chase, and Amanda Miles
Decision-Making During Percutaneous Coronary Intervention Guided by Optical Coherence Tomography: Insights From the LightLab Initiative., Brian Bergmark, Luis A P Dallan, Gabriel T R Pereira, Julia F Kuder, Sabina A Murphy, Jana Buccola, Jason R Wollmuth, John Lopez, Joia Spinelli, Jennifer Meinen, Nick E J West, and Kevin Croce
Data disaggregation: the case of Asian and Pacific Islander data and the role of health sciences librarians, Seema Bhakta
Data disaggregation: the case of Asian and Pacific Islander data and the role of health sciences librarians., Seema Bhakta
Drug-Drug Interactions With Paxlovid and Select CV Medications, Nicole Martin Bhave, Tyler J Gluckman, and Barbara S. Wiggins
Drug-Drug Interactions With Nirmatrelvir/Ritonavir (Paxlovid) and Select Cardiovascular Medications, Nicole M. Bhave, Ty J. Gluckman, and Barbara S. Wiggins
Cancer Patient Care Journey 2.0: Don't Get Left Behind, Carlo Bifulco
Enhancing clinical genomics datasets with multimodal EHR data and imaging, Carlo Bifulco
Genomic Models of Practice That Support the Quadruple Aim, Carlo Bifulco
Lightning talks: AI in healthcare, Carlo Bifulco
Spatial Biology: a Cambrian Explosion of Technology, Carlo Bifulco
The virtual molecular tumor board as a tool for integrating omics in the delivery of precision oncology, Carlo Bifulco
Enhancing Clinical Genomics Datasets with Multimodal EHR Data and Imaging, Carlo Bifulco and Brian Piening
Value of Comprehensive Genomic Profiling on Clinical Actionability and Treatment in Advanced Cancer Patients, C Bifulco, B Bapat, R Weerasinghe, R Meng, A Dowdell, A Vita, S Chang, M Campbell, B Schroeder, and B Piening
A Random Forest Genomic Classifier for Tumor Agnostic Prediction of Response to Anti-PD1 Immunotherapy., Emma Bigelow, Suchi Saria, Brian D. Piening, Brendan Curti, Alexa K Dowdell, Roshanthi Weerasinghe, Carlo Bifulco, Walter Urba, Noam Finkelstein, Elana J Fertig, Alex Baras, Neeha Zaidi, Elizabeth Jaffee, and Mark Yarchoan
Autoimmune Hemolytic Anemia in Children: Laboratory Investigation, Disease Associations, and Treatment Strategies., Douglas Blackall and Lily Dolatshahi
Fluorescence tagging to monitor CD8 T cell recirculation from the tumor to the tumor-draining lymph node: the impact of focal radiation therapy on recirculation, TC Blair, Brian D. Piening, Marka R Crittenden, Michael J. Gough, and See full list of authors in comments
ICOS is upregulated on T cells following radiation and agonism combined with radiation results in enhanced tumor control., Tiffany Blair, Jason Baird, Shelly Bambina, Gwen Kramer, Monica Gostissa, Christopher J Harvey, Michael J Gough, and Marka R Crittenden
Fluorescent tracking identifies key migratory dendritic cells in the lymph node after radiotherapy., Tiffany Blair, Shelly Bambina, Gwen Kramer, Alexa K Dowdell, Alejandro F Alice, Jason R Baird, Amanda W Lund, Brian D. Piening, Marka R Crittenden, and Michael J. Gough
Praluzatamab ravtansine, a CD166-targeting antibody-drug conjugate, in patients with advanced solid tumors: an open-label phase 1/2 trial., Valentina Boni, Mary J Fidler, Hendrik-Tobias Arkenau, Alexander Spira, Funda Meric-Bernstam, Nataliya Uboha, Rachel E Sanborn, Randy F Sweis, Patricia LoRusso, Misako Nagasaka, Javier Garcia-Corbacho, Shadia Jalal, James J Harding, Stella K Kim, Iris H C Miedema, Danielle J Vugts, Marc C Huisman, Gerben J C Zwezerijnen, Guus A M S van Dongen, Catharina W Menke-van der Houven van Oordt, Song Wang, Tam Dang, Ivan A Zein, Olga Vasiljeva, Susan K Lyman, Virginia Paton, Alison Hannah, and Joyce F Liu
Temporal trends and predictors of surgical ablation for atrial fibrillation across a multistate healthcare system., Scott Brancato, Mansen Wang, Kateri Spinelli, Maheer Gandhavadi, Neil Worrall, Eric J Lehr, Zachary M DeBoard, Torin P. Fitton, Alison Leiataua, Jonathan P Piccini, and Tyler J Gluckman
997 T cell immunotherapies trigger neutrophils to eliminates heterogenous tumors, Sadna Budha, Rebekka Duhen, Andrew Weinberg, and See all authors in comments
Vessel Wall Enhancement in Unilateral Primary Angiitis of the Central Nervous System., Adrian Budhram, Shailee S Shah, Christopher P Wood, Michael A Lane, Kyle E Smoot, and Brian G Weinshenker
Safety of Fingolimod in Patients with Multiple Sclerosis Switched from Natalizumab: Results from TRANSITION-A 2-Year, Multicenter, Observational, Cohort Study., Helmut Butzkueven, Paul S Giacomini, Stanley Cohan, Tjalf Ziemssen, Daniel Sienkiewicz, Ying Zhang, Yvonne Geissbühler, Diego Silva, Davorka Tomic, Harald Kropshofer, and Maria Trojano
Editorial: Cancer Immunotherapies: From Efficacy to Resistance Mechanisms., Janin Chandra, Morten Hansen, Nathalie Labarriere, Ilaria Marigo, Fernando Souza-Fonseca-Guimaraes, Lazar Vujanovic, Yoshinobu Koguchi, and Nicolas Jacquelot
Takotsubo Syndrome Among Patients with Spontaneous Coronary Artery Dissection: A Report of the ISCAD Registry, G Chi, LM Tam, and See all authors in comments
Impact of a Laboratory-Developed Phenotypic Rapid Susceptibility Test Directly From Positive Blood Cultures on Time to Narrowest Effective Therapy in Patients With Gram-Negative Bacteremia: A Prospective Randomized Trial., Alyssa B Christensen, Brent Footer, Tobias Pusch, Kim Heath, Maha Iqbal, Lian Wang, Gregory Tallman, Cameron J Cover, Jennifer Marfori, Brian A Kendall, Nicholas L Stucky, Meagan Greckel, Ivor Thomas, Katelynn Tran, Salena Yip, and Margret Oethinger
Neoadjuvant chemotherapy improves outcomes in resectable pancreatic adenocarcinoma, Wade Christopher, Sean Nassoiy, Rebecca Marcus, Jennifer Keller, Shu-Ching Chang, Trevan Fischer, Anton Bilchik, and Melanie Goldfarb
Changes in T-cell subsets and clonal repertoire during chemoimmunotherapy with pembrolizumab and paclitaxel or capecitabine for metastatic triple-negative breast cancer., Brie Chun, Joanna Pucilowska, Shu-Ching Chang, Isaac Kim, Benjamin Nikitin, Yoshinobu Koguchi, William L. Redmond, Brady Bernard, Venkatesh Rajamanickam, Nathan Polaske, Paul A Fields, Valerie Conrad, Mark Schmidt, Walter Urba, Alison Conlin, Heather L McArthur, and David B Page
The Two Sides of Siponimod: Evidence for Brain and Immune Mechanisms in Multiple Sclerosis., Stanley Cohan, Ralph H B Benedict, Bruce A C Cree, John DeLuca, Le H Hua, and Jerold Chun
Impact of oral health integration training on children's receipt of oral assessment, fluoride varnish and dental services., Hannah Cohen-Cline, Jannate Ahmed, Megan Holtorf, Laura McKeane, and Sarah Bartelmann
Local Housing Choice Voucher Distribution Policies Impact Healthcare Utilization: a Randomized Natural Experiment., Hannah Cohen-Cline, Kyle G Jones, and Keri B Vartanian
CT243 / 4 - Phase 1 study of TAK-676 + pembrolizumab following radiation therapy in patients with advanced non-small-cell lung cancer (NSCLC), triple-negative breast cancer (TNBC), or squamous-cell carcinoma of the head and neck (SCCHN), Benjamin Cooper, David B Page, and See full list of authors in comments
TAK-676 in combination with pembrolizumab after radiation therapy in patients (pts) with advanced non–small cell lung cancer (NSCLC), triple-negative breast cancer (TNBC), or squamous-cell carcinoma of the head and neck (SCCHN): Phase 1 study design., Benjamin T. Cooper and David B Page
Correlates of 90-Day Mortality Among People Who Do and Do Not Inject Drugs With Infective Endocarditis in Seattle, Washington., Maria A Corcorran, Jenell Stewart, Kristine Lan, Ayushi Gupta, Sara N Glick, Chetan Seshadri, Kevin J Koomalsingh, Edward F Gibbons, Robert D Harrington, Shireesha Dhanireddy, and H Nina Kim
IVIG Research Project, K Couch and ST Chiu
Automated Staging of Breast Cancer Histopathology Images Using Deep Learning, A Crabtree, N Naik, J Searcy, G Srinivasa, C Bifulco, K Matlock, and B Piening
The Economic Impact of Lower Extremity Peri-Prosthetic Fractures in a Large Hospital System., James P Crutcher, Geoffrey Tompkins, Genevieve Rollier, Katie Sypher, Rebecca Valderrama, and Paul J Duwelius
For Ethical Fundraising from Patients, Respect them as Partners., Brendan Curti
Chapter 72: Cancer of the Skin, Brendan Curti, Sancy Leachman, and Walter Urba
Intratumoral oncolytic virus V937 plus ipilimumab in patients with advanced melanoma: the phase 1b MITCI study., Brendan Curti, Jon Richards, John R Hyngstrom, Gregory A Daniels, Mark Faries, Lynn Feun, Kim A Margolin, Sigrun Hallmeyer, Mark Grose, Yiwei Zhang, Anlong Li, and Robert H I Andtbacka
Development and validation of a model to calculate anesthetic agent consumption from inspired and end-expired concentrations, minute ventilation, fresh gas flow and dead space ventilation., Louise Cuveele, Jan F A Hendrickx, Andre M De Wolf, Sofie De Cooman, Brian B. Chesebro, Jeffrey Feldman, and Jodi Sherman
Dose escalation of davoceticept, a conditional CD28 costimulator and dual checkpoint inhibitor, in advanced malignancies (NEON-1), Diwakar Davar, Rachel E Sanborn, and See full list of authors in comments
Phase 1 study of SEA-TGT, a human, nonfucosylated monoclonal antibody directed to TIGIT with enhanced immune effector function, in patients with advanced malignancies (SGNTGT-001, trial in progress), D Davar, Rachel E Sanborn, and See full list of authors in comments
Case: Stent Thrombosis – Attacked on All Fronts, C H. Davies
Case: Stent Thrombosis – Attacked on All Fronts, CH Davies
Examining Acute Coronary Syndrome Across Ethnicity, Sex, and Age, Kristofer De Leon and Elizabeth Winokur
Climate Change: A Crisis for Family Medicine Educators., Monica DeMasi, Bhargavi Chekuri, Heather L Paladine, and Tina Kenyon
Transcatheter Aortic Valve Replacement for Severe Aortic Regurgitation in Patients With a Left Ventricular Assist Device., Ashwat S Dhillon, Brandon Jones, Robert W. Hodson, and Ethan C Korngold
PIVOT IO 001: First disclosure of efficacy and safety of bempegaldesleukin (BEMPEG) plus nivolumab (NIVO) vs NIVO monotherapy in advanced melanoma (MEL), A Diab, Brendan Curti, and See all authors in comments
ASHP Foundation Pharmacy Forecast 2022: Strategic Planning Guidance for Pharmacy Departments in Hospitals and Health Systems., Joseph T DiPiro, Jannet M Carmichael, Vivian B Johnson, Monika N Daftary, Leyner Martinez, Michelle D Wiest, Binita Patel, Tom Woller, Elva Van Devender, Rita Shane, and Francesca Cunningham
546 A phase I dose escalation study of STEMVAC, a multi-antigen, multi-epitope Th1 selective plasmid-based vaccine, targeting stem cell associated proteins in patients with advanced breast cancer, Mary Disis, Sasha Stanton, and See all authors in comments
Getting Clear About Fuzzy Matching: A Guide to Matching Administrative Data Sets, Taylor Doren, Chia-Hua Yu, and Benjamin Gronowski
Automatic Patient Matching for Genome-Guided Adoptive Cell Immunotherapy Trials at a Large Health System, Alexa K Dowdell, Tucker Bower, Benjamin Cosgrove, Roshanthi Weerasinghe, Ann Vita, Brian D. Piening, Carlo Bifulco, Eric Tran, and Rom Leidner
OX40 agonist stimulation increases and sustains humoral and cell-mediated responses to SARS-CoV-2 protein and saRNA vaccines., Rebekka Duhen, Michael Beymer, Shawn M. Jensen, Srinivas Abbina, Suraj Abraham, Nikita Jain, Anitha Thomas, Andrew J Geall, Hong-Ming Hu, Bernard A Fox, and Andrew D Weinberg
PD-1 and ICOS co-expression identifies tumor-reactive CD4 T cells in human solid tumors., Rebekka Duhen, Olivier Fesneau, Kimberly Samson, Alexandra K Frye, Michael Beymer, Venkatesh Rajamanickam, David Ross, Eric Tran, Brady Bernard, Andrew D Weinberg, and Thomas Duhen
OX40 boosts and sustains humoral and cellular immune responses to SARS-CoV-2 spike protein and RNA vaccinations, R Duhen, Bernard A Fox, Andrew D Weinberg, and See all authors in comments
Aperçu de l’immunothérapie et défis de l’immuno-oncologie, T Duhen
PD-1 and ICOS co-expression identifies tumor-reactive CD4 T cells in human solid tumors, Thomas Duhen
Carfilzomib-Induced Thrombotic Microangiopathy: Focus on Pathogenesis., Odianosen Eigbire-Molen, Daniela Hermelin, and Douglas Blackall
Real-world burden of chemotherapy-induced myelosuppression in patients with small cell lung cancer: a retrospective analysis of electronic medical data from community cancer care providers., Robert S. Epstein, Roshanthi Weerasinghe, Amy S. Parrish, JoAnn Krenitsky, Rachel E Sanborn, and Tehseen Salimi
T Cells Engineered to Express Immunoreceptors Targeting the Frequently Expressed Medullary Thyroid Cancer Antigens Calcitonin, CEA, and RET M918T., Timothy A Erickson, Yi-Ping Shih, Joseph Fass, Myungkyu Jang, and Eric Tran
Speaking Up for Patient Safety: Will Nurses Report Errors Now a Nurse Has Been Convicted of a Criminal Act?, Cyndi Evans, Jovie Jabla, Geary A Gardner, Taranjeet Rathore, and Elizabeth Ann Scruth
Aldosterone Blocking Agent In-Hospital Prescription Based on Implementation of the ACC Patient Navigator Program: Focus MI, C Eza-Nliam, Ty Gluckman, and See all authors in comments
Chapter: High-Sensitivity C-Reactive Protein, David I. Feldman, Roger S. Blumenthal, and Ty J. Gluckman
A Phase II, Single-arm Trial of Sunitinib and Erlotinib in Advanced Renal Cell Carcinoma., Zizhen Feng, Brendan Curti, David I Quinn, John M Strother, Zunqiu Chen, Rebecca Agnor, Tomasz M Beer, and Christopher W Ryan
Phase II Randomized Trial of Transoral Surgery and Low-Dose Intensity Modulated Radiation Therapy in Resectable p16+ Locally Advanced Oropharynx Cancer: An ECOG-ACRIN Cancer Research Group Trial (E3311)., Robert L Ferris, Yael Flamand, Gregory S Weinstein, Shuli Li, Harry Quon, Ranee Mehra, Joaquin J Garcia, Christine H Chung, Maura L Gillison, Umamaheswar Duvvuri, Bert W O'Malley, Enver Ozer, Giovana R Thomas, Wayne M Koch, Neil D Gross, Richard Bryan Bell, Nabil F Saba, Miriam Lango, Eduardo Méndez, and Barbara Burtness
A Review of the Clinical and Cost Effectiveness of Intravenous and Intramuscular Pharmacological Treatment on Acute Agitation in Patients Admitted to the Emergency Department, Ryan Ferris and Carol Keller
Identification of a subset of tumor-reactive CD8 TILs expressing NKG2A in HNSCC and CRC., O Fesneau, Thomas Duhen, and See full list of authors in comments
Identification of a subset of tumor-reactive CD8 TIL expressing NKG2A in HNSCC and CRC, O Fesneau, K Samson, V Rajamanickam, D Ross, and Thomas Duhen
Post-Operative Mitral Valve Intervention Hemostasis in Patients that Receive Vitamin K Supplementation, Torin P. Fitton
A Vision for Personalizing Treatments to Overcome Cancer’s Escape Mechanisms and Improve Outcomes for Patients, Bernard Fox
Cancer Vaccines: A Phoenix Rising from the Ashes, Bernard Fox
Combining 10x scRNA-seq and 100 plex mIF: Too much data or complimentary technologies to examine what works, Bernard Fox
Complex Cancer Vaccines: An Approach to Induce Immunity Against Gastroesophageal Malignancies in 2022, Bernard Fox
Comprehensive Spatial Phenotyping: Mapping the Tumor Microenvironment at Scale, Bernard Fox
Immune Activating and Cancer Vaccine Technology, Bernard Fox
Overview of Immunotherapy and Challenges for Immuno-Oncology, Bernard Fox
Recommended phase 2 dose (RP2D) of HB-200 arenavirus-based cancer immunotherapies in patients with HPV16+ cancers., Siqing Fu, Rom Leidner, and Matthew H Taylor
Functional status at 30 and 90 days after mild ischaemic stroke., Hannah Gardener, Leo A Romano, Eric E Smith, Iszet Campo-Bustillo, Yosef Khan, Sofie Tai, Nikesha Riley, Ralph L Sacco, Pooja Khatri, Heather M Alger, Brian Mac Grory, Deepak Gulati, Navdeep S Sangha, Karin E Olds, Curtis G Benesch, Adam G Kelly, Scott S Brehaut, Amit Kansara, Lee H Schwamm, and Jose G Romano
Management of Anorectal Malformations and Hirschsprung Disease., Colin D Gause and Sanjay Krishnaswami
Video game rehabilitation for outpatient stroke (VIGoROUS): A multi-site randomized controlled trial of in-home, self-managed, upper-extremity therapy., Lynne V Gauthier, Deborah S Nichols-Larsen, Gitendra Uswatte, Nancy Strahl, Marie Simeo, Rachel Proffitt, Kristina Kelly, Roger Crawfis, Edward Taub, David Morris, Linda Pax Lowes, Victor Mark, and Alexandra Borstad
A Phase 1 Study of TAK-676, a Novel STING Agonist, Plus Pembrolizumab Following Radiation Therapy in Patients with Advanced Non–Small-Cell Lung Cancer (NSCLC), Triple-Negative Breast Cancer (TNBC), or Squamous-Cell Carcinoma of the Head and Neck (SCCHN), NK Gerber, DB Page, and See all authors in comments
