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Submissions from 2021

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Facebook Live: COVID-19, Homeschooling and Teen Mental Health, Roseann Gretchell and Tyson Payne

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Germinal center reactions in tertiary lymphoid structures associate with neoantigen burden, humoral immunity and long-term survivorship in pancreatic cancer., Andrew J Gunderson, Venkatesh Rajamanickam, Cynthia Bui, Brady Bernard, Joanna Pucilowska, Carmen Ballesteros-Merino, Mark Schmidt, Kayla McCarty, Michaela Philips, Brian D. Piening, Christopher Dubay, Terry R Medler, Phillipa Newell, Paul D Hansen, Eric Tran, Ephraim Tang, Carlo Bifulco, Marka R Crittenden, Michael J. Gough, and Kristina H Young

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Population Health Innovations and Payment to Address Social Needs Among Patients and Communities With Diabetes., Kathryn E Gunter, Monica E Peek, Jacob P Tanumihardjo, Evalyn Carbrey, Richard D Crespo, Trista W Johnson, Brenda Rueda-Yamashita, Eric I Schwartz, Catalina Sol, Cody M Wilkinson, J O Wilson, Emily Loehmer, and Marshall H Chin

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LB180 - Clinical biomarker studies with two fusion-enhanced versions of oncolytic HSV (RP1 and RP2) alone and in combination with nivolumab in cancer patients indicate potent immune activation, Kevin J. Harrington, Francesca Aroldi, Joseph J. Sacco, Mohammed M. Milhem, Brendan Curti, Ari M. Vanderwalde, Scott Baum, Adel Samson, Anna C. Pavlick, Jason A. Chesney, Jiaxin Niu, Terence D. Rhodes, Tawnya L. Bowles, Robert Conry, Anna Olsson-Brown, Douglas E. Laux, Pablo Nenclares, Lavita Menezes, Alex Deterding, Victoria Roulstone, Joan Kyula, Suzanne Thomas, Praveen K. Bommareddy, Selda Samakoglu, Andrea Pirzkall, Robert S. Coffin, and Mark R. Middleton

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The frequency of medical reversals in a cross-sectional analysis of high-impact oncology journals, 2009-2018., Alyson Haslam, Jennifer Gill, Tyler Crain, Diana Herrera-Perez, Emerson Y Chen, Talal Hilal, Myung S Kim, and Vinay Prasad

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The frequency of assessment of progression in randomized oncology clinical trials., Alyson Haslam, Jennifer Gill, and Vinay Prasad

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Facebook Live: Social Isolation and how it affects mental health, Robin Henderson and Brette Borow

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Clinical Outcomes Associated With Acute Mechanical Circulatory Support Utilization in Heart Failure Related Cardiogenic Shock., Jaime Hernandez-Montfort, Shashank S Sinha, Katherine L Thayer, Evan H Whitehead, Mohit Pahuja, Arthur Reshad Garan, Claudius Mahr, Jillian L Haywood, Neil M Harwani, August Schaeffer, Detlef Wencker, Manreet Kanwar, Esther Vorovich, Jacob Abraham, Daniel Burkhoff, and Navin K Kapur

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First report of the safety/tolerability and preliminary antitumor activity of HB-201 and HB-202, an arenavirus-based cancer immunotherapy, in patients with HPV16+ cancers., Alan L. Ho, Marshall R. Posner, and Rom Leidner

Age-friendly health systems: Creating meaningful change in outpatient primary care, MO Hodges and Colleen Casey

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Mogamulizumab in Combination with Nivolumab in a Phase I/II Study of Patients with Locally Advanced or Metastatic Solid Tumors., David S Hong, Olivier Rixe, Vi K Chiu, Patrick M Forde, Tomislav Dragovich, Yanyan Lou, Asha Nayak-Kapoor, Rom Leidner, James N Atkins, Agron Collaku, Floyd E Fox, Margaret A Marshall, and Anthony J Olszanski

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Healthcare utilization and cost outcomes for a multicenter first seizure and new onset epilepsy clinic., Emily R Hudson, Alexandra Lesko, Lindsay Lucas, Elizabeth Baraban, and Evan J Fertig

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Right Ventricular Dysfunction Is Common and Identifies Patients at Risk of Dying in Cardiogenic Shock., Pankaj Jain, Katherine L Thayer, Jacob Abraham, Kay D Everett, Mohit Pahuja, Evan H Whitehead, Benjamin P Schwartz, Anuradha Lala, Shashank S Sinha, Manreet K Kanwar, A Reshad Garan, Jaime A Hernandez-Monfort, Claudius Mahr, Esther Vorovich, Detlef Wencker, James M McCabe, Tara Jones, Maithri Goud, Paulina Baca, Neil Harwani, Daniel Burkhoff, and Navin K Kapur

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Initial results of a first-in-human, dose escalation study of a cell-based vaccine in HLA A*02+ patients (pts) with recurrent, locally advanced or metastatic HPV16+ solid tumors: SQZ-PBMC-HPV-101., Antonio Jimeno, Joaquina C. Baranda, Matthew H Taylor, and See all authors in comments

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Continuous Monitoring of Risk-Adjusted Outcomes: Excess Deaths vs. Lives Saved., Ruyun Jin, Gary L Grunkemeier, and Anthony P Furnary

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Phase I, First-in-Human Study of the Probody Therapeutic CX-2029 in Adults with Advanced Solid Tumor Malignancies., Melissa Johnson, Anthony El-Khoueiry, Navid Hafez, Nehal Lakhani, Hirva Mamdani, Jordi Rodon, Rachel E Sanborn, Javier Garcia-Corbacho, Valentina Boni, Mark Stroh, Alison L Hannah, Song Wang, Henry Castro, and Alexander Spira

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Comparable Outcomes for Transcarotid and Transfemoral Transcatheter Aortic Valve Replacement at a High Volume US Center., Brandon Jones, V Kumar, Shih-Ting Chiu, Ethan C Korngold, Robert W. Hodson, Kateri Spinelli, and Eric B Kirker

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Health and Health Care Use Strongly Associated with Cumulative Burden of Social Determinants of Health., Kyle G Jones, Sarah E Roth, and Keri B Vartanian

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Health and Health Care Use Strongly Associated with Cumulative Burden of Social Determinants of Health, Kyle G Jones and Keri B Vartanian

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Rapid, successful adoption of virtual outpatient cardiology care during the COVID-19 pandemic, Lesley Jones Larson, D Christensen, S Long, Lian Wang, Kateri Spinelli, and Xiaoyan Huang

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Do small baby units improve extremely premature infant outcomes?, Joseph W Kaempf and Kanekal Gautham

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Impact of Age on Outcomes in Patients With Cardiogenic Shock., Manreet Kanwar, Katherine L Thayer, Arthur Reshad Garan, Jaime Hernandez-Montfort, Evan Whitehead, Claudius Mahr, Shashank S Sinha, Esther Vorovich, Neil M Harwani, Elric Zweck, Jacob Abraham, Daniel Burkhoff, and Navin K Kapur

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Impact of age on outcomes in patients with cardiogenic shock, M Kanwar, KL Thayer, A Garan, J Hernandez-Montfort, EH Whitehead, C Mahr, S Sinha, E Vorovich, NM Harwani, E Zweck, Jacob Abraham, and D Burkhoff

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Multi-omic Profiling of Simultaneous Ductal Carcinoma In Situ and Invasive Breast Cancer, Henry G. Kaplan, Anna B. Berry, Alexa Dowdell, and Brian D. Piening

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Treatment of PCM1-JAK2 fusion tyrosine kinase gene-related acute lymphoblastic leukemia with stem cell transplantation, Henry G Kaplan, Carlo Bifulco, Ruyun Jin, James M Scanlan, and David Colvin

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Safety and efficacy of daclizumab beta in patients with relapsing multiple sclerosis in a 5-year open-label study (EXTEND): final results following early termination., Ludwig Kappos, Stanley Cohan, Douglas L Arnold, Randy R Robinson, Joan Holman, Sami Fam, Becky Parks, Shan Xiao, and Wanda Castro-Borrero

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Facebook Live: Her Heart Health: Spotlight on Women's Heart Program, Laurie Kelly and Lori Tam

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Treatment dependent improvements in survival of stage 2/3 rectal cancer patients treated with trimodality therapy between 2006-2016, an NCDB analysis., Hagen F Kennecke, Henry T. Bahnson, and See list of authors in comments

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CCTG CO.28 primary endpoint analysis: Neoadjuvant chemotherapy, excision and observation for early rectal cancer, the NEO trial., Hagen F Kennecke, Carl J. Brown, and See full list of authors in comments

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Noninvasive biomarkers for prediction and diagnosis of heart transplantation rejection., Yeraz Khachatoorian, Vahe Khachadourian, Eleanor Chang, Erick R Sernas, Elaine F Reed, Mario Deng, Brian D. Piening, Alexandre C Pereira, Brendan Keating, and Martin Cadeiras

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"Custom" Plate in a Day-Accurate Predictive Hole Fabrication Using Point-of-Care 3-Dimensional Printing., Baber Khatib, Marcus Couey, Ashish Patel, Allen C Cheng, and Richard Bryan Bell

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Updates in Management of Craniomaxillofacial Gunshot Wounds and Reconstruction of the Mandible., Baber Khatib, Savannah Gelesko, Melissa Amundson, Allen Cheng, Ashish Patel, Tuan Bui, Eric J Dierks, and R Bryan Bell

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A Case Series of Metastatic Metaplastic Breast Carcinoma Treated With Anti-PD-1 Therapy., Isaac Kim, Venkatesh Rajamanickam, Brady Bernard, Brie Chun, Yaping Wu, Maritza Martel, Zhaoyu Sun, William L Redmond, Katherine Sanchez, Reva Basho, Heather McArthur, and David B Page

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The Benefits of Transcarotid Access for Transcatheter Aortic Valve Replacement: When will we stop being so surprised?, Eric B Kirker and Brandon Jones

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Hospital Procedure Volume Not Associated with 30-day Stroke Rate for Transcarotid or Transaxillary/Subclavian TAVR., Eric Kirker and Brandon Jones

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Trough levels of ipilimumab in serum as a potential biomarker of clinical outcomes for patients with advanced melanoma after treatment with ipilimumab., Yoshinobu Koguchi, Noriko Iwamoto, Takashi Shimada, Shu-Ching Chang, John Cha, Brendan Curti, Walter Urba, Brian D. Piening, and William L. Redmond

Alternative access: Transcarotid, Ethan C Korngold

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Changes in Carcinoid Syndrome Symptoms Among Patients Receiving Telotristat Ethyl in US Clinical Practice: Findings from the TELEPRO-II Real-World Study., Matthew H Kulke, Hagen F Kennecke, Kris Murali, and Vijay N Joish

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Unaltered IL-2 encapsulated in acoustically active lipid microspheres for systemic but targeted microdose delivery to tumor microenvironment., Clayton Larsen, Llew Keltner, William L. Redmond, and Rhodemann Li

Cardiovascular risk assessment and disease management in patients with cancer, Michael Layoun

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Chapter: Cardiovascular complications, Michael Layoun and M Ferencik

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Lenvatinib plus pembrolizumab in patients with either treatment-naive or previously treated metastatic renal cell carcinoma (Study 111/KEYNOTE-146): a phase 1b/2 study., Chung-Han Lee, Amishi Yogesh Shah, Drew Rasco, Arpit Rao, Matthew H Taylor, Christopher Di Simone, James J Hsieh, Alvaro Pinto, David R Shaffer, Regina Girones Sarrio, Allen Lee Cohn, Nicholas J Vogelzang, Mehmet Asim Bilen, Sara Gunnestad Ribe, Musaberk Goksel, Øyvind Krohn Tennøe, Donald Richards, Randy F Sweis, Jay Courtright, Daniel Heinrich, Sharad Jain, Jane Wu, Emmett V Schmidt, Rodolfo F Perini, Peter Kubiak, Chinyere E Okpara, Alan D Smith, and Robert J Motzer

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Neoadjuvant immunoradiotherapy results in high rate of complete pathological response and clinical to pathological downstaging in locally advanced head and neck squamous cell carcinoma., Rom Leidner, Marka Crittenden, Kristina Young, Hong Xiao, Yaping Wu, Marcus A Couey, Ashish A Patel, Allen C Cheng, Amber L Watters, Carlo Bifulco, George Morris, Lessli Rushforth, Shorin Nemeth, Walter J Urba, Michael Gough, and R Bryan Bell

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Cancer microenvironment and genomics: evolution in process., Stanley P Leong, Isaac P Witz, Orit Sagi-Assif, Sivan Izraely, Jonathan Sleeman, Brian Piening, Bernard A Fox, Carlo B Bifulco, Rachel Martini, Lisa Newman, Melissa Davis, Lauren M Sanders, David Haussler, Olena M Vaske, and Marlys Witte

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Pembrolizumab with low-dose carboplatin for recurrent platinum-resistant ovarian, fallopian tube, and primary peritoneal cancer: survival and immune correlates., John B Liao, William R Gwin, Renata R Urban, Katie M Hitchcock-Bernhardt, Andrew L Coveler, Doreen M Higgins, Jennifer S Childs, Hania N Shakalia, Ron E Swensen, Sasha E Stanton, Anna V Tinker, Tanya A Wahl, Richard G Ancheta, Kathryn F McGonigle, James Y Dai, Mary L Disis, and Barbara A Goff

Dry Field Closure of Large-Bore Access With Iliac Artery Angioplasty Through the Ipsilateral Sheath: The Single-Access Dry-Closure Technique., Hady Lichaa, Jason R Wollmuth, and Rajiv Tayal

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Pediatric Endoscopy Quality Improvement Network (PEnQuIN) Pediatric Endoscopy Reporting Elements: A Joint NASPGHAN/ESPGHAN Guideline., Jenifer R Lightdale, Catharine M Walsh, Douglas S Fishman, Raoul I Furlano, Petar Mamula, Peter M Gillett, Priya Narula, Iva Hojsak, Salvatore Oliva, Matjaž Homan, Matthew R Riley, Hien Q Huynh, Joel R Rosh, Kevan Jacobson, Marta Tavares, Ian H Leibowitz, Elizabeth C Utterson, Nicholas M Croft, David R Mack, Herbert Brill, Quin Y Liu, Patrick Bontems, Diana G Lerner, Jorge Amil-Dias, Robert E Kramer, Anthony R Otley, Lusine Ambartsumyan, Veronik Connan, Graham A McCreath, Mike A Thomson, and PEnQuIN Working Group

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Pediatric Endoscopy Quality Improvement Network (PEnQuIN) Quality Standards and Indicators for Pediatric Endoscopy Facilities: A Joint NASPGHAN/ESPGHAN Guideline., Jenifer R Lightdale, Catharine M Walsh, Priya Narula, Elizabeth C Utterson, Marta Tavares, Joel R Rosh, Matthew R Riley, Salvatore Oliva, Petar Mamula, David R Mack, Quin Y Liu, Diana G Lerner, Ian H Leibowitz, Kevan Jacobson, Hien Q Huynh, Matjaž Homan, Iva Hojsak, Peter M Gillett, Raoul I Furlano, Douglas S Fishman, Nicholas M Croft, Herbert Brill, Patrick Bontems, Jorge Amil-Dias, Robert E Kramer, Lusine Ambartsumyan, Anthony R Otley, Graham A McCreath, Veronik Connan, Mike A Thomson, and PEnQuIN Working Group

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Pediatric Endoscopy Quality Improvement Network (PEnQuIN) Quality Standards and Indicators for Pediatric Endoscopic Procedures: A Joint NASPGHAN/ESPGHAN Guideline., Jenifer R Lightdale, Catharine M Walsh, Salvatore Oliva, Kevan Jacobson, Hien Q Huynh, Matjaž Homan, Iva Hojsak, Peter M Gillett, Raoul I Furlano, Douglas S Fishman, Nicholas M Croft, Herbert Brill, Patrick Bontems, Jorge Amil-Dias, Elizabeth C Utterson, Marta Tavares, Joel R Rosh, Matthew R Riley, Priya Narula, Petar Mamula, David R Mack, Quin Y Liu, Diana G Lerner, Ian H Leibowitz, Anthony R Otley, Robert E Kramer, Lusine Ambartsumyan, Veronik Connan, Graham A McCreath, Mike A Thomson, and PEnQuIN Working Group

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Disrupting tumour vasculature and recruitment of aPDL1-loaded platelets control tumour metastasis., Hongjun Li, Zejun Wang, Zhaowei Chen, Tianyuan Ci, Guojun Chen, Di Wen, Ruoxin Li, Jinqiang Wang, Huan Meng, R Bryan Bell, Zhifeng Gu, Gianpietro Dotti, and Zhen Gu

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Artificial Intelligence-Assisted Electrocardiography for Early Diagnosis of Thyrotoxic Periodic Paralysis., Chin Lin, Chin-Sheng Lin, Ding-Jie Lee, Chia-Cheng Lee, Sy-Jou Chen, Shi-Hung Tsai, Feng-Chih Kuo, Tom Chau, and Shih-Hua Lin

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Plasma Lipidomic Patterns in Patients with Symptomatic Coronary Microvascular Dysfunction., Jonathan R Lindner, Brian P Davidson, Zifeng Song, Claudia S Maier, Jessica Minnier, Jan Frederick Stevens, Maros Ferencik, Sahar Taqui, J Todd Belcik, Federico Moccetti, Michael Layoun, Paul Spellman, Mitchell S Turker, Hagai Tavori, Sergio Fazio, Jacob Raber, and Gerd Bobe

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Effects of yoga, cognitive behavioral therapy, and a behavioral placebo on sleep: A nationwide multicenter phase III RCT in cancer survivors., Po-Ju Lin, Charles E. Heckler, Alison Conlin, and See full list of authors in comments

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Characterization of the immune response in patients with cancer of the oral cavity after neoadjuvant immunotherapy with the IRX-2 regimen., Siyu Liu, Emily Bellile, Ariane Nguyen, Katie Zarins, Nisha D'Silva, Laura Rozek, Gregory T Wolf, Maureen A Sartor, INSPIRE Trial Clinical Investigators, and Richard Bryan Bell

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The impact of an accountable care unit on mortality: an observational study., Laura Loertscher, Lian Wang, and Shelley Schoepflin Sanders

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Caregiver-Oncologist Prognostic Concordance, Caregiver Mastery, and Caregiver Psychological Health and Quality of Life., Kah Poh Loh, Mostafa R Mohamed, Sindhuja Kadambi, Eva Culakova, Huiwen Xu, Allison Magnuson, Marie Flannery, Paul R Duberstein, Ronald M Epstein, Colin McHugh, Ryan D Nipp, Kelly M Trevino, Chandrika Sanapala, Bianca A Hall, Beverly Canin, Arlene A Gayle, Alison Conlin, James Bearden, and Supriya G Mohile

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Proportion of days covered as a measure of medication adherence., Jennifer Loucks, Autumn D Zuckerman, Angelica Berni, Adam Saulles, Gosia Thomas, and Amy Alonzo

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Simulating for Quality: A Centralized Quality Improvement and Patient Safety Simulation Curriculum for Residents and Fellows., Jacob T Luty, Hayden Oldham, Andrea Smeraglio, Matthew DiVeronica, Christopher Terndrup, Frederick A Tibayan, Joshua Engle, Kimberly Lepin, and Stephanie Nonas

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Neoadjuvant immunotherapy is reshaping cancer management across multiple tumour types: The future is now!, Michele Maio, Christian Blank, Andrea Necchi, Anna Maria Di Giacomo, Ramy Ibrahim, Michael Lahn, Bernard A Fox, R Bryan Bell, Giampaolo Tortora, and Alexander M M Eggermont

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A vision of immuno-oncology: the Siena think tank of the Italian network for tumor biotherapy (NIBIT) foundation., Michele Maio, Michael Lahn, Anna Maria Di Giacomo, Alessia Covre, Luana Calabrò, Ramy Ibrahim, Bernard Fox, and Siena Think Tank

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354 Lenvatinib and pembrolizumab in advanced endometrial carcinoma (EC): long-term efficacy and safety update from a phase 1b/2 study, Vicky Makker, Matthew H Taylor, and See full list of authors in comments

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Adjuvant T-DM1 versus trastuzumab in patients with residual invasive disease after neoadjuvant therapy for HER2-positive breast cancer: subgroup analyses from KATHERINE., E P Mamounas, M Untch, M S Mano, C-S Huang, C E Geyer, G von Minckwitz, N Wolmark, X Pivot, S Kuemmel, M P DiGiovanna, B Kaufman, G Kunz, A K Conlin, J C Alcedo, T Kuehn, I Wapnir, A Fontana, J Hackmann, J Polikoff, M Saghatchian, A Brufsky, Y Yang, M Zimovjanova, T Boulet, H Liu, D Tesarowski, L H Lam, C Song, M Smitt, and S Loibl

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A phase I/II study of rovalpituzumab tesirine in delta-like 3-expressing advanced solid tumors., Aaron S Mansfield, David S Hong, Christine L Hann, Anna F Farago, Himisha Beltran, Saiama N Waqar, Andrew E Hendifar, Lowell B Anthony, Matthew H Taylor, Alan H Bryce, Scott T Tagawa, Karl Lewis, Jiaxin Niu, Christine H Chung, James M Cleary, Michael Rossi, Carrianne Ludwig, Ricardo Valenzuela, Yan Luo, and Rahul Aggarwal

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Finding Our Stride: A Health System Repository 4 Years In / Providence Patents: Using an Institutional Repository to Promote Technology Transfer, Heather J. Martin and Amanda Schwartz

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Phosphorylation of SMAD3 in immune cells predicts survival of patients with early stage non-small cell lung cancer., Sebastian Marwitz, Carmen Ballesteros-Merino, Shawn M. Jensen, Martin Reck, Christian Kugler, Sven Perner, Daniel Drömann, Torsten Goldmann, and Bernard A Fox

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POEM: clinical outcomes beyond 5 years., Sarah C McKay, Christy M Dunst, Ahmed M Sharata, Reid Fletcher, Kevin M Reavis, Daniel Davila Bradley, Steven R DeMeester, Dolores Müller, Brett Parker, and Lee L Swanström

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Defining Immunogenic and Radioimmunogenic Tumors., Terry R Medler, Tiffany C Blair, Marka R Crittenden, and Michael J Gough

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Safety of the APOLLO Onyx delivery microcatheter for embolization of brain arteriovenous malformations: results from a prospective post-market study., Philip M Meyers, Johanna T Fifi, Kevin M Cockroft, Timothy R Miller, Curtis A Given, Ali R Zomorodi, Bharathi D Jagadeesan, Maxim Mokin, Peter Kan, Tom L Yao, Orlando Diaz, Daniel Huddle, Richard J Bellon, Joshua Seinfeld, Adam J Polifka, David Fiorella, Rohan V Chitale, Peter Kvamme, Jay T Morrow, Justin Singer, Ajay K Wakhloo, Ajit S Puri, Vivek Deshmukh, Ricardo A Hanel, L Fernando Gonzalez, Henry H Woo, and Mohammad Ali Aziz-Sultan

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Facebook Live: Strategic Facility Planning in a rapidly changing health care environment, John Milne, Hillary Altmann, Michelle Bernard, and Suzanne Schwab

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Translational Advances in Cancer Prevention Agent Development (TACPAD) Virtual Workshop on Immunomodulatory Agents: Report., Altaf Mohammed, Roderick H Dashwood, Sally Dickinson, Mary L Disis, Elizabeth M Jaffee, Bryon D Johnson, Samir N Khleif, Michael N Pollak, Jeffrey Schlom, Robert H Shoemaker, Sasha Stanton, Georg T Wondrak, Ming You, Hao Zhu, and Mark Steven Miller

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A Randomized Trial of Fulvestrant, Everolimus, and Anastrozole for the Front-line Treatment of Patients with Advanced Hormone Receptor-positive Breast Cancer, SWOG S1222., Halle C F Moore, William E Barlow, George Somlo, Julie R Gralow, Anne F Schott, Daniel F Hayes, Peter Kuhn, James B Hicks, Lisa Welter, Philip A Dy, Christina H Yeon, Alison Conlin, Ernie Balcueva, Danika L Lew, Debasish Tripathy, Lajos Pusztai, and Gabriel N Hortobagyi

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Atezolizumab, Bevacizumab, and Chemotherapy for Newly Diagnosed Stage III or IV Ovarian Cancer: Placebo-Controlled Randomized Phase III Trial (IMagyn050/GOG 3015/ENGOT-OV39)., Kathleen N Moore, Michael Bookman, Jalid Sehouli, Austin Miller, Charles Anderson, Giovanni Scambia, Tashanna Myers, Cagatay Taskiran, Katina Robison, Johanna Mäenpää, Lyndsay Willmott, Nicoletta Colombo, Jessica Thomes-Pepin, Michalis Liontos, Michael A Gold, Yolanda Garcia, Sudarshan K Sharma, Christopher J Darus, Carol Aghajanian, Aikou Okamoto, Xiaohua Wu, Rustem Safin, Fan Wu, Luciana Molinero, Vidya Maiya, Victor K Khor, Yvonne G Lin, and Sandro Pignata

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HDAC inhibition prevents transgene expression downregulation and loss-of-function in T-cell-receptor-transduced T cells., Tamson V Moore, Gina M Scurti, Matthew DeJong, Siao-Yi Wang, Annika V Dalheim, Courtney R Wagner, Kelli A Hutchens, Jodi J Speiser, Constantine V Godellas, Chris Fountain, Jessica Fleser, Tarsem Moudgil, Mallory Thomas, David Murray, Brendan D Curti, Joseph I Clark, Bernard A Fox, and Michael I Nishimura

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Lenvatinib plus Pembrolizumab or Everolimus for Advanced Renal Cell Carcinoma., Robert Motzer, Boris Alekseev, Sun-Young Rha, Camillo Porta, Masatoshi Eto, Thomas Powles, Viktor Grünwald, Thomas E Hutson, Evgeny Kopyltsov, María J Méndez-Vidal, Vadim Kozlov, Anna Alyasova, Sung-Hoo Hong, Anil Kapoor, Teresa Alonso Gordoa, Jaime R Merchan, Eric Winquist, Pablo Maroto, Jeffrey C Goh, Miso Kim, Howard Gurney, Vijay Patel, Avivit Peer, Giuseppe Procopio, Toshio Takagi, Bohuslav Melichar, Frederic Rolland, Ugo De Giorgi, Shirley Wong, Jens Bedke, Manuela Schmidinger, Corina E Dutcus, Alan D Smith, Lea Dutta, Kalgi Mody, Rodolfo F Perini, Dongyuan Xing, Toni K Choueiri, CLEAR Trial Investigators, and Brendan Curti (CLEAR Trial Investigators)

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85 Detection of human angiotensin-converting enzyme 2 receptor (hACE2R) on human cancer cell lines, Tarsem Moudgil, Bernard A Fox, and Hong-Ming Hu

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Induction of ADAM10 by RT drives fibrosis, resistance, and EMT in pancreatic cancer., Adam C Mueller, Miles Piper, Andrew Goodspeed, Shiv Bhuvane, Jason S Williams, Shilpa Bhatia, Andy V Phan, Benjamin Van Court, Kathryn L Zolman, Brisa Peña, Ayman J Oweida, Sara Zakem, Cheryl Meguid, Michael W Knitz, Laurel Darragh, Thomas E Bickett, Jacob Gadwa, Luisa Mestroni, Matthew R G Taylor, Kimberly R Jordan, Peter Dempsey, M Scott Lucia, Martin D McCarter, Marco Del Chiaro, Wells A Messersmith, Richard D Schulick, Karyn A Goodman, Michael J. Gough, Casey S Greene, James C Costello, Antonio Galvao Neto, David Lagares, Kirk C Hansen, Adrie Van Bokhoven, and Sana D Karam

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High Resolution Manometry in a Functioning Fundoplication - Establishing a Standard Profile: Retrospective Chart Review., Dolores T Müller, Brett Parker, Reid Fletcher, Ahmed M Sharata, Daniel Davila Bradley, Steven R DeMeester, Kevin M Reavis, Lee L Swanstrom, and Christy M Dunst

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Regulation of MRE11A by UBQLN4 leads to cisplatin resistance in patients with esophageal squamous cell carcinoma., Tomohiro Murakami, Yoshiaki Shoji, Tomohiko Nishi, Shu-Ching Chang, Ron D Jachimowicz, Sojun Hoshimoto, Shigeshi Ono, Yosef Shiloh, Hiroya Takeuchi, Yuko Kitagawa, Dave Hoon, and Matias Bustos

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509 A first-in-human phase 1 study of NL-201 in patients with relapsed or refractory cancer, Aung Naing, Brendan Curti, and See full list of authors in comments

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Proteogenomic Characterization of Highly Enriched Viable Leukemic Blasts in Acute Myeloid Leukemia: A SWOG Report, Jasmine Naru, John E Godwin, and See full list of authors in comments

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Overall Survival Benefit with Tebentafusp in Metastatic Uveal Melanoma., Paul Nathan, Jessica C Hassel, Piotr Rutkowski, Jean-Francois Baurain, Marcus O Butler, Max Schlaak, Ryan J Sullivan, Sebastian Ochsenreither, Reinhard Dummer, John M Kirkwood, Anthony M Joshua, Joseph J Sacco, Alexander N Shoushtari, Marlana Orloff, Josep M Piulats, Mohammed Milhem, April K S Salama, Brendan Curti, Lev Demidov, Lauris Gastaud, Cornelia Mauch, Melinda Yushak, Richard D Carvajal, Omid Hamid, Shaad E Abdullah, Chris Holland, Howard Goodall, Sophie Piperno-Neumann, and IMCgp100-202 Investigators

Impella 5.5 as a bridge to repair in a post-infarct ventricular septal defect, Vidang P. Nguyen, Ethan C Korngold, and Jacob Abraham

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1665 - QuPath versus InForm: Digital image analysis of multiplex immunofluorescence (mIF) tumor-infiltrating lymphocyte (TIL) outcomes in an immunotherapy clinical trial, Benjamin Nikitin, Brie Chun, Isaac Kim, William L. Redmond, Katherine Sanchez, Zhaoyu Sun, Yaping Wu, and David B Page

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Atezolizumab Plus Chemotherapy for First-Line Treatment of Nonsquamous NSCLC: Results From the Randomized Phase 3 IMpower132 Trial., Makoto Nishio, Fabrice Barlesi, Howard West, Simon Ball, Rodolfo Bordoni, Manuel Cobo, Pascale Dubray Longeras, Jerome Goldschmidt, Silvia Novello, Francisco Orlandi, Rachel E Sanborn, Zsuzsanna Szalai, Grigoriy Ursol, Diana Mendus, Lijia Wang, Xiaohui Wen, Mark McCleland, Tien Hoang, See Phan, and Mark A Socinski

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Allogeneic Transplantation in Fit Older Adults Is Feasible and Encouragingly Efficacious. Post Remission Data from the Prospective ECOG-ACRIN (E2906) Clinical Study, Yishai Ofran, John E Godwin, and See full list of authors in comments

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Unconscious Bias and Self-Care:: Key Components of an Integrated, Comprehensive Health Care System Nurse Manager Leadership Development Program, LeAnn Ogilvie, Troy Larkin, and Jan L. Keller-Unger

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Is the 21-Gene Recurrence Score on Core Needle Biopsy Equivalent to Surgical Specimen in Early-Stage Breast Cancer? A Comparison of Gene Expression Between Paired Core Needle Biopsy and Surgical Specimens., Javier I J Orozco, Shu-Ching Chang, Chikako Matsuba, Miquel Ensenyat-Mendez, Gary L Grunkemeier, Diego M Marzese, and Janie G Grumley

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ASO Visual Abstract: Is the 21-Gene Recurrence Score on Core Needle Biopsy Equivalent to Surgical Specimen in Early-Stage Breast Cancer? : A Comparison of Gene Expression Between Paired Core Needle Biopsy and Surgical Specimens., Javier I J Orozco, Shu-Ching Chang, Chikako Matsuba, Miquel Ensenyat-Mendez, Gary L Grunkemeier, Diego M Marzese, and Janie G Grumley

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Associations between complete remission and 2- to 3-year survival following 7 + 3 induction for acute myeloid leukemia., Megan Othus, Guillermo Garcia-Manero, John E Godwin, James Weick, Derek Stirewalt, Frederick Appelbaum, Harry Erba, and Elihu Estey

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Abstract P77: Acute Stroke Trends and Outcomes During the COVID-19 Pandemic in a Multi-System Hospital System in the Western US, Renee Ovando, Natalie Swearingen, Tamela Stuchiner, Leslie Corless, Crystal Ann Moreno, John Zurasky, Jason Tarpley, Radoslav Raychev, and Elizabeth Baraban

Advances in Immunotherapy, David B Page

Teaming up to Finish Triple-Negative Breast Cancer, David B Page

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399 A phase II study of nivolumab, ipilimumab, plus androgen receptor blockade with bicalutamide to enhance thymic T-cell production and immunotherapy response in metastatic breast cancer, David B Page, Krystle Collins, Brie Chun, Zhaoyu Sun, Yoshinobu Koguchi, William L. Redmond, Maritza Martel, Yaping Wu, Nikki Moxon, Staci Mellinger, Walter Urba, Ayca Gucalp, and Tiffany Traina

A phase II study of nivolumab, ipilimumab, plus androgen receptor blockade with bicalutamide to enhance thymic T-cell production and immunotherapy response in metastatic breast cancer, David B Page, Krystle Collins, Brie Chun, Zhaoyu Sun, Yoshinobu Koguchi, William D Ryan, Maritza Martel, Yaping Wu, Nikki Moxon, Staci Mellinger, Walter Urba, Ayca Gucalp, and Tiffany A. Traina

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OT1-18-04. A phase II study of dual immune checkpoint blockade (ICB) plus bicalutamide to enhance thymic T-cell production and immunotherapy response in metastatic breast cancer (MBC), David B Page, Krystle L. Collins, Brie Chun, Zhaoyu Sun, William L. Redmond, Maritza Martel, Yaping Wu, Nikki Moxon, Staci Mellinger, Walter Urba, Tiffany Traina, and Ayca Gucalp

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Postinfusion monitoring costs by site of care for patients with relapsed/refractory large B-cell lymphoma receiving third- or later-line treatment with lisocabtagene maraleucel in the TRANSCEND NHL 001 and OUTREACH trials., M Lia Palomba, Monika Parisi Jun, James Lymp, Andy Nguyen, November McGarvey, Matthew Gitlin, Corey Pelletier, Scott J Keating, and John Godwin

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Amivantamab in EGFR Exon 20 Insertion-Mutated Non-Small-Cell Lung Cancer Progressing on Platinum Chemotherapy: Initial Results From the CHRYSALIS Phase I Study., Keunchil Park, Eric B Haura, Natasha B Leighl, Paul Mitchell, Catherine A Shu, Nicolas Girard, Santiago Viteri, Ji-Youn Han, Sang-We Kim, Chee Khoon Lee, Joshua K Sabari, Alexander I Spira, Tsung-Ying Yang, Dong-Wan Kim, Ki Hyeong Lee, Rachel E Sanborn, José Trigo, Koichi Goto, Jong-Seok Lee, James Chih-Hsin Yang, Ramaswamy Govindan, Joshua M Bauml, Pilar Garrido, Matthew G Krebs, Karen L Reckamp, John Xie, Joshua C Curtin, Nahor Haddish-Berhane, Amy Roshak, Dawn Millington, Patricia Lorenzini, Meena Thayu, Roland E Knoblauch, and Byoung Chul Cho

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1247P - Management of infusion-related reactions (IRRs) in patients receiving amivantamab, K Park, JK Sabari, EB Haura, CA Shu, A Spira, R Salgia, KL Reckamp, Rachel E Sanborn, R Govindan, JM Bauml, JC Curtin, J Xie, A Roshak, P Lorenzini, D Millington, M Thayu, RE Knoblauch, and BC Cho

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TBX2 Drives Neuroendocrine Prostate Cancer through Exosome-Mediated Repression of miR-200c-3p., Girijesh Kumar Patel, Sayanika Dutta, Mosharaf Mahmud Syed, Sabarish Ramachandran, Monica Sharma, Venkatesh Rajamanickam, Vadivel Ganapathy, David J DeGraff, Kevin Pruitt, Manisha Tripathi, and Srinivas Nandana

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Anticoagulation Therapy Reduces Recurrent Stroke in Embolic Stroke of Undetermined Source Patients With Elevated Coagulation Markers or Severe Left Atrial Enlargement., Kishan Patel, Elio Mikhael, Michael Liu, Srikant Rangaraju, Deandra Ellis, Alexander Duncan, Samir Belagaje, Trina Belair, Laura Henriquez, and Fadi Nahab