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Submissions from 2019

Strategies to Stomp Out Unwanted Clinical Care Variation: A Case-Based Approach, Tyler J Gluckman

Tailoring LDL-C lowering therapy to patient cardiovascular risk: Identifying effective strategies for patients with diabetes, Tyler J Gluckman

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Transradial Access Strategy Provides Most Benefit for PCI-Related Bleeding, Tyler J Gluckman

Treating high-risk patients with non-statin therapy for LDL-C lowering: Optimizing clinical outcomes, Tyler J Gluckman

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Abstract 13987: Underutilization of Oral Anticoagulant Therapy in At-Risk Patients With Atrial Fibrillation—Insights From a Multistate Healthcare System, Tyler J Gluckman, Amir Ali, Mansen Wang, Howard Mun, Sally Alfred, and John L. Petersen

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Abstract 14012: Opportunities to Improve the Efficacy and Safety of Oral Anticoagulant Therapy in Atrial Fibrillation—Insights From a Multistate Healthcare System, Tyler J Gluckman, Amir Ali, Mansen Wang, Howard Mun, Sally Alfred, and John L. Petersen

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A PROmise to Improve Cardiovascular Care., Tyler J Gluckman, Lynne W Stevenson, and Richard Kovacs

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Streamlining Evaluation and Management Payment to Reduce Clinician Burden., Tyler J Gluckman and James J Vavricek

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Differential impact of bleeding avoidance strategies on risk-adjusted PCI-related bleeding rates within a large multistate health system, Tyler J Gluckman, L Wang, Kateri Spinelli, JL Petersen, P Huang, and SV Rao

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Recognition of human gastrointestinal cancer neoantigens by circulating PD-1+ lymphocytes., Alena Gros, Eric Tran, Maria R Parkhurst, Sadia Ilyas, Anna Pasetto, Eric M Groh, Paul F Robbins, Rami Yossef, Andrea Garcia-Garijo, Carlos A Fajardo, Todd D Prickett, Li Jia, Jared J Gartner, Satyajit Ray, Lien Ngo, John R Wunderllich, James C Yang, and Steven A Rosenberg

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Blockade of fibroblast activation protein in combination with radiation treatment in murine models of pancreatic adenocarcinoma., Andrew J Gunderson, Tomoko Yamazaki, Kayla McCarty, Michaela Phillips, Alejandro F Alice, Shelly Bambina, Lauren Zebertavage, David Friedman, Benjamin Cottam, Pippa Newell, Michael J. Gough, Marka R Crittenden, Pieter Van der Veken, and Kristina H Young

What Are These Squiggly Lines? Fast Basics to Interpret 12-Lead ECGs, Benjamin J Hartwig

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Review of evidence for bosentan therapy for treatment of Eisenmenger syndrome., Benjamin J Hartwig and Benjamin Schultze

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TCT-77 Transcarotid Versus Subclavian/Axillary Access for Transcatheter Aortic Valve Replacement: Real-World Comparative Outcomes Utilizing the TVT Registry, James Hermiller, David Heimansohn, Sina Moainie, Eric B Kirker, Ethan C Korngold, Robert W. Hodson, Adnan Chhatriwalla, John Saxon, Keith Allen, Raymond McKay, and Mohiuddin Cheema

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Intrathoracic complications associated with trans-femoral transcatheter aortic valve replacement: Implications for emergency surgical preparedness., Robert W. Hodson, Ruyun Jin, Michael Ring, Sameer Gafoor, Shawnna Verburg, Eric J Lehr, and Kateri Spinelli

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Multi-antigen Vaccination With Simultaneous Engagement of the OX40 Receptor Delays Malignant Mesothelioma Growth and Increases Survival in Animal Models., Peter R Hoffmann, Fukun W Hoffmann, Thomas A Premeaux, Tsuyoshi Fujita, Elisa Soprana, Maddalena Panigada, Glen M Chew, Guilhem Richard, Pooja Hindocha, Mark Menor, Vedbar S Khadka, Youping Deng, Lenny Moise, Lishomwa C Ndhlovu, Antonio Siccardi, Andrew D Weinberg, Anne S De Groot, and Pietro Bertino

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Monitoring therapeutic response and resistance: analysis of circulating tumor DNA in patients with ALK+ lung cancer., Leora Horn, Jennifer G Whisenant, Heather Wakelee, Karen L Reckamp, Huan Qiao, Ticiana A Leal, Liping Du, Jennifer Hernandez, Vincent Huang, George R Blumenschein, Saiama N Waqar, Sandip P Patel, Jorge Nieva, Geoffrey R Oxnard, Rachel E Sanborn, Tristan Shaffer, Kavita Garg, Allison Holzhausen, Kimberly Harrow, Chris Liang, Lee P Lim, Mark Li, and Christine M Lovly

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Circulating tumor (ct) DNA analysis to monitor response and resistance to ensartinib in patients (pts) with ALK+ non-small cell lung cancer (NSCLC)., L Horn, J G Whisenant, H Wakelee, K L Reckamp, H Qiao, L Du, J Hernandez, V Huang, S N Waqar, S Patel, R E Sanborn, T Shaffer, K Garg, A Holzhausen, K Harrow, C Liang, L P Lim, M Li, and C M Lovly

CCO 20: What can you do to prepare for value-based care, Xiaoyan Huang

HF Forum: Heart Failure Management Beyond Hospitalization, Xiaoyan Huang

Medical Neighborhood 20: Why Should Specialists Care?, Xiaoyan Huang

Prevention Forum: Cardiovascular Disease Prevention: Policy, Guidelines and Strategy, Xiaoyan Huang

Standardized Training of Cardiovascular Specialists: Bridging the Gap: Case Discussion, Xiaoyan Huang

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Transforming Specialty Practice in Pursuit of Value-Based Care: Results from an Integrated Cardiology Practice, Xiaoyan Huang, Lesley Jones Larson, Lian Wang, Kateri Spinelli, and Meredith Rosenthal

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Future Research Goals in Immunotherapy., Tyler W Hulett, Bernard A Fox, David J Messenheimer, Sebastian Marwitz, Tarsem Moudgil, Michael E Afentoulis, Keith W Wegman, Carmen Ballesteros-Merino, and Shawn M. Jensen

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Highlights from Selected Cardiovascular Disease Prevention Studies Presented at the 2019 European Society of Cardiology Congress., Xiaoming Jia, Mahmoud Al Rifai, Tyler J Gluckman, Yochai Birnbaum, and Salim S Virani

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Abstract 11163: Lipid Monitoring and Treatment Intensification of Cholesterol Lowering Therapies - Insight From the Veterans Affairs Healthcare System, Xiaoming Jia, David J. Ramsey, Mahmoud al Rifai, Sarah T. Ahmed, Julia M. Akeroyd, Dave L. Dixon, Tyler J Gluckman, Vijay Nambi, Christie M. Ballantine, Laura A. Petersen, Neil J. Stone, and Salim S. Virani

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Impact of Lipid Monitoring on Treatment Intensification of Cholesterol Lowering Therapies (from the Veterans Affairs Healthcare System)., Xiaoming Jia, David J Ramsey, Mahmoud Al Rifai, Sarah T Ahmed, Julia M Akeroyd, Dave L Dixon, Ty J Gluckman, Vijay Nambi, Christie M Ballantyne, Laura A Petersen, Neil J Stone, and Salim S Virani

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TCT-804 Outcomes of Trans-Carotid TAVR in a high-Volume Center, BM Jones, Ethan C Korngold, Robert W. Hodson, Shih-Ting Chiu, V Kumar, and Eric B Kirker

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Safety and Efficacy of Durvalumab and Tremelimumab Alone or in Combination in Patients with Advanced Gastric and Gastroesophageal Junction Adenocarcinoma., Ronan J Kelly, Jeeyun Lee, Yung-Jue Bang, Khaldoun Almhanna, Mariela Blum Murphy, Daniel V T Catenacci, Hyun Cheol Chung, Zev A Wainberg, Michael K Gibson, Keun-Wook Lee, Johanna C Bendell, Crystal S Denlinger, Cheng Ean Chee, Takeshi Omori, Rom Leidner, Heinz-Josef Lenz, Yee Chao, Marlon C Rebelatto, Philip Brohawn, Peng He, Jennifer McDevitt, Siddharth Sheth, Judson M Englert, and Geoffrey Y Ku

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TCT-142 Clinical Characteristics and Outcomes of Patients Undergoing Transcatheter Aortic Valve Replacement With STS PROM of ≤3%, Jackson King, Morgan Black, Ruyun Jin, Gary Grunkemeier, Brydan Curtis, Robert W. Hodson, and Michael Ring

Alternative Access Approaches in TAVR, Eric B Kirker

Case-Based Access Challenges Panel Discussant, Eric B Kirker

Structural IV Panel Discussant, Eric B Kirker

Live Case: Transcarotid TAVR, Eric B Kirker and Ethan C Korngold

Considerations for Managing TAVR and Concomitant Coronary Artery Disease in 2020: Challenging Coronary Access Case, Ethan C Korngold

CTO Crossing 1: Case Examples of Wire Escalation, Ethan C Korngold

Embrace Left Distal Radial Access: It’s the New and Best Approach!, Ethan C Korngold

Large-Bore Access and Closure: Resolution, Ethan C Korngold

Live Cases #6 - Live Case Discussant, Ethan C Korngold

Now That I See It, I Know How To Treat It! Presentation and Hands-On Session 1, Ethan C Korngold

Now That I See It, I Know How To Treat It! Presentation and Hands-On Session 2, Ethan C Korngold

PCI in the OBL/ASC Setting: Is it Safe?, Ethan C Korngold

SFA Intervention: De-Bulking, Complex Lesions, and Definitive Therapy - Training Pavilion Faculty, Ethan C Korngold

Structural Complications: Aortic Annular Rupture, And More, Ethan C Korngold

TAVR With Difficult Access: The Transcarotid Approach, Ethan C Korngold

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Drivers of High-Cost Medical Complexity in a Medicaid Population., David Labby, Bill J. Wright, Lauren Broffman, and Megan Holtorf

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Heart Failure Symptom Biology in Response to Ventricular Assist Device Implantation., Christopher S Lee, James O Mudd, Karen S Lyons, Quin E Denfeld, Corrine Y Jurgens, Bradley E Aouizerat, Jill M Gelow, Christopher V Chien, Emily Aarons, and Kathleen L Grady

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Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal Cancer., Winifred Lo, Maria Parkhurst, Paul F Robbins, Eric Tran, Yong-Chen Lu, Li Jia, Jared J Gartner, Anna Pasetto, Drew Deniger, Parisa Malekzadeh, Thomas E Shelton, Todd Prickett, Satyajit Ray, Scott Kivitz, Biman C Paria, Isaac Kriley, David S Schrump, and Steven A Rosenberg

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Solution Sets to Generate Actionable Knowledge for Cardiovascular Care., Thomas M Maddox, Tyler J Gluckman, John Doherty, and Richard J Kovacs

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Addressing current challenges and future directions in immuno-oncology: expert perspectives from the 2017 NIBIT Foundation Think Tank, Siena, Italy., Michele Maio, George Coukos, Soldano Ferrone, Bernard A Fox, Wolf H Fridman, Patrick L Garcia, Michael Lahn, Olivier Provendier, Vincenzo Russo, Dominik Rüttinger, Aiman Shalabi, Zlatko Trajanoski, Jean Viallet, Jedd D Wolchok, and Ramy Ibrahim

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Neoantigen screening identifies broad TP53 mutant immunogenicity in patients with epithelial cancers., Parisa Malekzadeh, Anna Pasetto, Paul F Robbins, Maria R Parkhurst, Biman C Paria, Li Jia, Jared J Gartner, Victoria Hill, Zhiya Yu, Nicholas P Restifo, Abraham Sachs, Eric Tran, Winifred Lo, Robert Pt Somerville, Steven A Rosenberg, and Drew C Deniger

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Neoantigen screening identifies broad TP53 mutant immunogenicity in patients with epithelial cancers., Parisa Malekzadeh, Anna Pasetto, Paul F Robbins, Maria R Parkhurst, Biman C Paria, Li Jia, Jared J Gartner, Victoria Hill, Zhiya Yu, Nicholas P Restifo, Abraham Sachs, Eric Tran, Winifred Lo, Robert Pt Somerville, Steven A Rosenberg, and Drew C Deniger

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Activating the Nucleic Acid-Sensing Machinery for Anticancer Immunity., Terry R Medler, Jaina M Patel, Alejandro Alice, Jason R Baird, Hong-Ming Hu, and Michael J Gough

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The role of estrogen, immune function and aging in heart transplant outcomes., Ashley E Morgan, Elizabeth Dewey, James O Mudd, Jill M Gelow, Jonathan Davis, Howard K Song, Frederick A Tibayan, and Castigliano M Bhamidipati

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2019 Methodology for Heart House Roundtables: A Report of the American College of Cardiology Solution Set Oversight Committee., Pamela B Morris, Richard J Kovacs, Larry A Allen, Lea G Binder, Kim K Birtcher, Ashleigh M Covington, Tyler J Gluckman, and Kim Allan Williams

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Anti-PD-1 monoclonal antibody MEDI0680 in a phase I study of patients with advanced solid malignancies., Aung Naing, Jeffrey Infante, Sanjay Goel, Howard Burris, Chelsea Black, Shannon Marshall, Ikbel Achour, Susannah Barbee, Rena May, Chris Morehouse, Kristen Pollizzi, Xuyang Song, Keith Steele, Nairouz Elgeioushi, Farzana Walcott, Joyson Karakunnel, Patricia LoRusso, Amy Weise, Joseph Eder, Brendan Curti, and Michael Oberst

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Use of "Research Techniques Made Simple" Series in Translational Topics Training in Dermatology at Oregon Health & Science University., Solveig Ophaug and Terry R Medler

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A phase Ib study of pre-operative, locoregional IRX-2 cytokine immunotherapy to prime immune responses in patients with early stage breast cancer., David B Page, Joanna Pucilowska, Katherine G Sanchez, Alison K Conlin, Anupama Acheson, Kelly S Perlewitz, James H Imatani, Shagheyegh Aliabadi-Wahle, Nikki Moxon, Staci Mellinger, Amanda Y Seino, Maritza Martel, Yaping Wu, Zhaoyu Sun, William L. Redmond, Valerie Conrad, Venkatesh Rajamanickam, Dottie Waddell, Deborah Laxague, Monil Shah, Shu-Ching Chang, and Walter Urba

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Anticoagulation risk assessment for patients with non-valvular atrial fibrillation and venous thromboembolism: A clinical review., Vincent A Pallazola, Rishi K Kapoor, Karan Kapoor, John W McEvoy, Roger S Blumenthal, and Ty J Gluckman

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First-In-Human Study of Cemiplimab Alone or In Combination with Radiotherapy and/or Low Dose Cyclophosphamide in Patients with Advanced Malignancies., Kyriakos P Papadopoulos, Melissa L Johnson, Albert Craig Lockhart, Kathleen N Moore, Gerald S Falchook, Silvia C Formenti, Aung Naing, Richard D Carvajal, Lee S Rosen, Glen J Weiss, Rom Leidner, Jingjin Li, Anne Paccaly, Minjie Feng, Elizabeth Stankevich, Israel Lowy, Matthew G Fury, and Marka R Crittenden

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Unique Neoantigens Arise from Somatic Mutations in Patients with Gastrointestinal Cancers., Maria R Parkhurst, Paul F Robbins, Eric Tran, Todd D Prickett, Jared J Gartner, Li Jia, Gabriel Ivey, Yong F Li, Mona El-Gamil, Almin Lalani, Jessica S Crystal, Abraham Sachs, Eric Groh, Satyajit Ray, Lien T Ngo, Scott Kivitz, Anna Pasetto, Rami Yossef, Frank J Lowery, Stephanie L Goff, Winifred Lo, Gal Cafri, Drew C Deniger, Parisa Malekzadeh, Mojgan Ahmadzadeh, John R Wunderlich, Robert P T Somerville, and Steven A Rosenberg

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Peritumoral administration of DRibbles-pulsed antigen-presenting cells enhances the antitumor efficacy of anti-GITR and anti-PD-1 antibodies via an antigen presenting independent mechanism., Jaina M Patel, Zhihua Cui, Zhi-Fa Wen, Catherine T Dinh, and Hong-Ming Hu

Assessing limb perfusion: New tools, Alejandro Perez

Medical management of the vascular surgery patient, Alejandro Perez

PAD/CLI: Medical Management, Alejandro Perez

Peripheral arterial disease for the wound care clinician, Alejandro Perez

Peripheral Artery Disease: Basic principles for the wound care clinician, Alejandro Perez

Screening for PAD/CLI, Alejandro Perez

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Comprehensive Genomic Tumor Profiling, Brian D. Piening

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Blockade of TGF-β signaling to enhance the antitumor response is accompanied by dysregulation of the functional activity of CD4, Magdalena J Polanczyk, Edwin Walker, Daniel Haley, Bella S Guerrouahen, and Emmanuel T Akporiaye

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OX40 Agonist Tumor Immunotherapy Does Not Impact Regulatory T Cell Suppressive Function., Fanny Polesso, Minhaz Sarker, Andrew D Weinberg, Susan E Murray, and Amy E Moran

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OX40 Agonist Tumor Immunotherapy Does Not Impact Regulatory T Cell Suppressive Function., Fanny Polesso, Minhaz Sarker, Andrew D Weinberg, Susan E Murray, and Amy E Moran

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Immunological Complexity of the Prostate Cancer Microenvironment Influences the Response to Immunotherapy., Nataliya Prokhnevska, Dana A Emerson, Haydn T Kissick, and William L. Redmond

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Non-TB Mycobacterial Infection-Bronchiectasis Nexus., Jerome M Reich

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Non-TB Mycobacterial Infection-Bronchiectasis Nexus., Jerome M Reich

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Two Radiographic Features Favoring Radiation Pneumonitis in the Differential Diagnosis., Jerome M Reich

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Current Controversies in Cardiothoracic Imaging: Low-dose Computerized Tomographic Overdiagnosis of Lung Cancer is Substantial; Its Consequences are Underappreciated-Point., Jerome M Reich and Jong S Kim

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Earlier Diagnosis Not Self-Evidently Beneficial: Natural History of Subcentimeter Lung Cancers., Jerome M Reich and Jong S Kim

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A Nurse Navigator-Driven Program to Increase Palliative Care Referrals for Advanced Heart Failure Patients, Margaret Richter, Linda DeSitter, Adam Mizgajski, and Deborah Strohecker

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Nurse-Led Navigator Program Increases Palliative Care Referrals For HF Patients, Margaret Richter, Linda DeSitter, Adam Mizgajski, and Deborah Strohecker

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Patient experiences in behavioral health integrated primary care settings: the role of stigma in shaping patient outcomes over time., Natalie Royal Kenton, Lauren Broffman, Kyle G Jones, Kayla Albrecht Mcmenamin, Maggie Weller, Kristin Brown, Jessica Currier, and Bill J. Wright

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Immunotherapy Toxicities., Katherine Sanchez, David B Page, and Walter Urba

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Management of spontaneous coronary artery dissection complicated by cardiogenic shock using mechanical circulatory support with the Impella device., Shilpa Sharma, Samantha Polak, Zachary George, John LeDoux, Richard Sohn, Adam Stys, Cathy Jeon, Yousef Ghazzawi, and Malissa Wood

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High-Dose Ipilimumab and High-Dose Interleukin-2 for Patients With Advanced Melanoma., Ann W Silk, Howard L Kaufman, Brendan Curti, Janice M Mehnert, Kim Margolin, David McDermott, Joseph Clark, Jenna Newman, Praveen K Bommareddy, Lisa Denzin, Saltanat Najmi, Azra Haider, Weichung Shih, Michael P Kane, and Andrew Zloza

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Immunotherapy for Head and Neck Cancer., Felix Sim, Rom Leidner, and Richard Bryan Bell

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Immunotherapy for Head and Neck Cancer., Felix Sim, Rom Leidner, and Richard Bryan Bell

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Immunotherapy for Head and Neck Cancer., Felix Sim, Rom Leidner, and Richard Bryan Bell

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Major pathologic response on biopsy (MPRbx) in patients with advanced melanoma treated with anti-PD-1: evidence for an early, on-therapy biomarker of response., J E Stein, A Soni, L Danilova, T R Cottrell, T F Gajewski, F S Hodi, S Bhatia, W J Urba, W H Sharfman, M Wind-Rotolo, R Edwards, E J Lipson, and J M Taube

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Subcellular compartmentalization of PKM2 identifies anti-PKM2 therapy response in vitro and in vivo mouse model of human non-small-cell lung cancer., Akiko Suzuki, Sachin Puri, Pamela Leland, Ankit Puri, Tarsem Moudgil, Bernard A Fox, Raj K Puri, and Bharat H Joshi

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Could a Stop-Bill Process Tied to EHR Help Ensure Correct MI-Related Coding?, Renee Swanson

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Process to Ensure Correct Classification of Myocardial Infarction-Related Deaths, Renee Swanson, Hannah Berg, Joanna Herzog, Curt Kandra, Cindy Keithley, Daniel Westerdahl, Adam Mizgajski, and Tyler J Gluckman

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Abstract 15943: Phenotypes of Cardiogenic Shock Associated With Increasing In-Hospital Mortality: A Report From The National Cardiogenic Shock Working Group Registry, Katherine Thayer, Sarah Newman, Mohyee Ayouty, Lena Jorde, Reshad Garan, Jaime Hernandez Montfort, Claudius Mahr, Detlef Wencker, Shashank S. Sinha, Esther Vorovich, Jacob Abraham, William O'Neill, Daniel Burkhoff, and Navin K. Kapur

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TCT-812 Modified SCAI Classification for Cardiogenic Shock Is Associated With Increasing In-Hospital Mortality: A Report From the Cardiogenic Shock Working Group Registry, Katherine Thayer, Sarah Newman, Lija Swain, Arthur Garan, Jaime Hernandez-Montfort, Claudius Mahr, Mohyee Ayouty, Shashank Sinha, Esther Vorovich, Jacob Abraham, and Navin Kapur

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Penetration, Completeness, and Representativeness of The Society of Thoracic Surgeons General Thoracic Surgery Database for Lobectomy., Betty C Tong, Sunghee Kim, Andrzej Kosinski, Mark W Onaitis, Daniel J Boffa, Robert H Habib, Joe B Putnam, Anthony P Furnary, Patricia Cowper, Cameron D Wright, Jeffrey P Jacobs, and Felix G Fernandez

Establishing a treatment pathway for patients with ruptured abdominal aortic aneurysms, Brant Ullery

Evolution of vascular complications and associated treatment strategies in transfemoral transcatheter aortic valve replacement, Brant Ullery

Expanding applicability of TEVAR in the fragile aorta, Brant Ullery

Five-year outcomes from the ENGAGE global registry: treating more challenging anatomy with excellent long-term outcomes, Brant Ullery

I think my patient had claudication, what do I do now?, Brant Ullery