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Submissions from 2017

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Spine Surgery Outcomes in Elderly Patients Versus General Adult Patients in the United States: A MarketScan Analysis., Carlito Lagman, Beatrice Ugiliweneza, Maxwell Boakye, and Doniel Drazin

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Intensive care unit procedure utilization at the end of life among patients with cancer: a community hospital network experience The American Thoracic Society Washington DC, AS Laliberte, Candice L. Wilshire, and See all authors in comments

Mycobacterium bovis Bacillus Calmette-Guérin Alters Melanoma Microenvironment Favoring Antitumor T Cell Responses and Improving M2 Macrophage Function, Ricardo D Lardone, Alfred A Chan, Agnes F Lee, Leland J Foshag, Mark B Faries, Peter A Sieling, and Delphine J Lee

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Protocol adherence for continuously titrated interventions in randomized trials: an overview of the current methodology and case study., F Lauzier, N K Adhikari, A Seely, K K Y Koo, E P Belley-Côté, K E A Burns, D J Cook, F D'Aragon, B Rochwerg, M E Kho, S J W Oczkowksi, E H Duan, M O Meade, A G Day, and F Lamontagne

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Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade., Dung T Le, Jennifer N Durham, Kellie N Smith, Hao Wang, Bjarne R Bartlett, Laveet K Aulakh, Steve Lu, Holly Kemberling, Cara Wilt, Brandon S Luber, Fay Wong, Nilofer S Azad, Agnieszka A Rucki, Dan Laheru, Ross Donehower, Atif Zaheer, George A Fisher, Todd S Crocenzi, James J Lee, Tim F Greten, Austin G Duffy, Kristen K Ciombor, Aleksandra D Eyring, Bao H Lam, Andrew Joe, S Peter Kang, Matthias Holdhoff, Ludmila Danilova, Leslie Cope, Christian Meyer, Shibin Zhou, Richard M Goldberg, Deborah K Armstrong, Katherine M Bever, Amanda N Fader, Janis Taube, Franck Housseau, David Spetzler, Nianqing Xiao, Drew M Pardoll, Nickolas Papadopoulos, Kenneth W Kinzler, James R Eshleman, Bert Vogelstein, Robert A Anders, and Luis A Diaz

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Airway stent complications: the role of follow-up bronchoscopy as a surveillance method., Hans J Lee, Wassim Labaki, Diana H Yu, Benjamin Salwen, Christopher R Gilbert, Andrea L C Schneider, Ricardo Ortiz, David Feller-Kopman, Sixto Arias, and Lonny Yarmus

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The Importance of Standardization on Analyzing Circulating RNA., Inyoul Lee, David Baxter, Min Young Lee, Kelsey Scherler, and Kai Wang

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Editorial Comment., J Joy Lee

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Remodeling of heterochromatin structure slows neuropathological progression and prolongs survival in an animal model of Huntington's disease., Junghee Lee, Yu Jin Hwang, Yunha Kim, Min Young Lee, Seung Jae Hyeon, Soojin Lee, Dong Hyun Kim, Sung Jae Jang, Hyoenjoo Im, Sun-Joon Min, Hyunah Choo, Ae Nim Pae, Dong Jin Kim, Kyung Sang Cho, Neil W Kowall, and Hoon Ryu

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Invited Commentary., Eric J Lehr

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High Agreement Between Benchtop and Point-of-Care Dipcard Tests for Ethyl Glucuronide., Emily Leickly, Jordan Skalisky, Sterling McPherson, Michael F Orr, and Michael G McDonell

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Device-associated thrombus formation after left atrial appendage occlusion: A systematic review of events reported with the Watchman, the Amplatzer Cardiac Plug and the Amulet., Mathieu Lempereur, Adel Aminian, Xavier Freixa, Sameer Gafoor, Joelle Kefer, Apostolos Tzikas, Victor Legrand, and Jacqueline Saw

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Left Atrial Appendage Occlusion in Patients With Atrial Fibrillation and Previous Major Gastrointestinal Bleeding (from the Amplatzer Cardiac Plug Multicenter Registry)., Mathieu Lempereur, Adel Aminian, Xavier Freixa, Sameer Gafoor, Samera Shakir, Heyder Omran, Sergio Berti, Gennaro Santoro, Joelle Kefer, Ulf Landmesser, Jens Erik Nielsen-Kudsk, Ignacio Cruz-Gonzalez, Prapa Kanagaratnam, Fabian Nietlispach, Reda Ibrahim, Horst Sievert, Wolfgang Schillinger, Jai-Wun Park, Steffen Gloekler, and Apostolos Tzikas

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Potential drug interaction with opioid agonist in the setting of chronic low-dose opioid antagonist use., James B Leonard, Vidya Nair, Christopher J Diaz, Jonathan B Penoyar, and Penelope A Goode

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Global kidney health 2017 and beyond: a roadmap for closing gaps in care, research, and policy., Adeera Levin, Marcello Tonelli, Joseph Bonventre, Josef Coresh, Jo-Ann Donner, Agnes B Fogo, Caroline S Fox, Ron T Gansevoort, Hiddo J L Heerspink, Meg Jardine, Bertram Kasiske, Anna Köttgen, Matthias Kretzler, Andrew S Levey, Valerie A Luyckx, Ravindra Mehta, Orson Moe, Gregorio Obrador, Neesh Pannu, Chirag R Parikh, Vlado Perkovic, Carol Pollock, Peter Stenvinkel, Katherine R Tuttle, David C Wheeler, and Kai-Uwe Eckardt

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Surgical occlusion of the left atrial appendage and thromboembolic complications in patients with left ventricular assist devices., Rebecca S Lewis, Lian Wang, Kateri J Spinelli, Gary Y Ott, and Jacob Abraham

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Cognitive Trajectory Changes Over 20 Years Before Dementia Diagnosis: A Large Cohort Study., Ge Li, Eric B Larson, Jane B Shofer, Paul K Crane, Laura E Gibbons, Wayne McCormick, J D Bowen, and Mary Lou Thompson

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Annotation of Alternatively Spliced Proteins and Transcripts with Protein-Folding Algorithms and Isoform-Level Functional Networks., Hongdong Li, Yang Zhang, Yuanfang Guan, Rajasree Menon, and Gilbert S Omenn

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Emerging Utility of Urinary Cell-free Nucleic Acid Biomarkers for Prostate, Bladder, and Renal Cancers., Selena Y Lin, Jennifer A Linehan, Timothy G Wilson, and Dave S B Hoon

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Modulation of Bax and mTOR for Cancer Therapeutics., Rui Li, Chunyong Ding, Jun Zhang, Maohua Xie, Dongkyoo Park, Ye Ding, Guo Chen, Guojing Zhang, Melissa Gilbert-Ross, Wei Zhou, Adam I Marcus, Shi-Yong Sun, Zhuo G Chen, Gabriel L Sica, Suresh S Ramalingam, Andrew T Magis, Haian Fu, Fadlo R Khuri, Walter J Curran, Taofeek K Owonikoko, Dong M Shin, Jia Zhou, and Xingming Deng

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Clinical Q & A: Translating Therapeutic Temperature Management from Theory to Practice., Sarah Livesay, Stephen A Figueroa, Leslie A Hamilton, William D Cahoon, and Patricia A Blissitt

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Catheter-Associated Urinary Tract Infection (CAUTI) Prevention Strategy Using Education in an Intensive Care Unit (ICU), Laura M. Locke, Cynthia Louise Grissman, Rita Denise Crasta, Gisele Nicole Bazan, Kari Love, Cindy Ford, Jamie K. Roney, and JoAnn D. Long

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Bcl11b and combinatorial resolution of cell fate in the T-cell gene regulatory network., William J R Longabaugh, Weihua Zeng, Jingli A Zhang, Hiroyuki Hosokawa, Camden S Jansen, Long Li, Maile Romero-Wolf, Pentao Liu, Hao Yuan Kueh, Ali Mortazavi, and Ellen V Rothenberg

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SmartScope2: Simultaneous Imaging and Reconstruction of Neuronal Morphology., Brian Long, Zhi Zhou, Ali Cetin, Jonathan Ting, Ryder Gwinn, Bosiljka Tasic, Tanya Daigle, Ed Lein, Hongkui Zeng, Peter Saggau, Michael Hawrylycz, and Hanchuan Peng

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Adaptive Prediction Emerges Over Short Evolutionary Time Scales., Adrián López García de Lomana, Amardeep Kaur, Serdar Turkarslan, Karlyn D Beer, Fred D Mast, Jennifer J Smith, John D Aitchison, and Nitin S Baliga

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Catastrophes and complicated intraoperative events during robotic lung resection., Brian E Louie

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Is tissue the issue?, Brian E Louie

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A Phase II Clinical Trial of an Aromatase Inhibitor for Postmenopausal Women with Lymphangioleiomyomatosis., Calvin Lu, Hye-Seung Lee, George P Pappas, Daniel F Dilling, Charles D Burger, Adrian Shifren, Srihari Veeraraghavan, Jeffrey T Chapman, Joseph Parambil, Stephen J Ruoss, Lisa R Young, Stephen R Hammes, Elizabeth J Kopras, Tammy Roads, Jeffrey P Krischer, and Francis X McCormack

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Allocation of Physician Time in Ambulatory Practice., Join Y Luh

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Anatomical complications of epidural anesthesia: A comprehensive review., Prasanthi Maddali, Marc Moisi, Jeni Page, Parthasarathi Chamiraju, Christian Fisahn, Rod Oskouian, and R Shane Tubbs

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Development of a Tool to Identify Problems Related to Medication Adherence in Home Healthcare Patients., Kathryn R Mahan, Jeffrey A Clark, Kurt D Anderson, Nolan J Koller, and Brian J Gates

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Mechanisms of radiotherapy-associated cognitive disability in patients with brain tumours., Milan T Makale, Carrie R McDonald, Jona A Hattangadi-Gluth, and Santosh Kesari

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An integrated transcriptomics-guided genome-wide promoter analysis and next-generation proteomics approach to mine factor(s) regulating cellular differentiation., Kamal Mandal, Samuel L Bader, Pankaj Kumar, Dipankar Malakar, David S Campbell, Bhola Shankar Pradhan, Rajesh K Sarkar, Neerja Wadhwa, Souvik Sensharma, Vaibhav Jain, Robert L Moritz, and Subeer S Majumdar

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Recessive mutations in SLC35A3 cause early onset epileptic encephalopathy with skeletal defects., Carla Marini, Katia Hardies, Tiziana Pisano, Patrick May, Sarah Weckhuysen, Elena Cellini, Arvid Suls, Davide Mei, Rudi Balling, Peter D Jonghe, Ingo Helbig, Domenico Garozzo, and Renzo Guerrini

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Crops In Silico: Generating Virtual Crops Using an Integrative and Multi-scale Modeling Platform, Amy Marshall-Colon, Stephen P Long, Douglas K Allen, Gabrielle Allen, Daniel A Beard, Bedrich Benes, Susanne von Caemmerer, A J Christensen, Donna J Cox, John C Hart, Peter M Hirst, Kavya Kannan, Daniel S Katz, Jonathan P Lynch, Andrew J Millar, Balaji Panneerselvam, Nathan D Price, Przemyslaw Prusinkiewicz, David Raila, Rachel G Shekar, Stuti Shrivastava, Diwakar Shukla, Venkatraman Srinivasan, Mark Stitt, Matthew J Turk, Eberhard O Voit, Yu Wang, Xinyou Yin, and Xin-Guang Zhu

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The price of whole-genome sequencing may be decreasing, but who will be sequenced?, Deborah A Marshall, Karen V MacDonald, Jill Oliver Robinson, Lisa F Barcellos, Milena Gianfrancesco, Monica Helm, Amy McGuire, Robert C Green, Michael P Douglas, Michael A Goldman, and Kathryn A Phillips

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Chiari I Malformation and Spinal Cord Ischemia in a Cadaver., Faizullah Mashriqi, Marios Loukas, Rod J Oskouian, Anthony V D'Antoni, and R Shane Tubbs

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The need for a network to establish and validate predictive biomarkers in cancer immunotherapy., Giuseppe V Masucci, Alessandra Cesano, Alexander Eggermont, Bernard A Fox, Ena Wang, Francesco M Marincola, Gennaro Ciliberto, Kevin Dobbin, Igor Puzanov, Janis Taube, Jennifer Wargo, Lisa H Butterfield, Lisa Villabona, Magdalena Thurin, Michael A Postow, Paul M Sondel, Sandra Demaria, Sanjiv Agarwala, and Paolo A Ascierto

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Community network lung cancer screening experience underrepresents medically underserved and geographically remote individuals, BM McCall, Candice L. Wilshire, CC Fuller, CR Gilbert, JT Fathi, JR Handy, KE Costas, BE Louie, RW Aye, AS Farivar, E Vallières, and JA Gorden

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The PeptideAtlas of the Domestic Laying Hen., James McCord, Zhi Sun, Eric W Deutsch, Robert L Moritz, and David C Muddiman

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Pretreatment ethyl glucuronide levels predict response to a contingency management intervention for alcohol use disorders among adults with serious mental illness., Michael Gerard McDonell, Emily Leickly, Sterling McPherson, Jordan Skalisky, Katherine Hirchak, Oladunni Oluwoye, Debra Srebnik, John Michael Roll, and Richard Kirkland Ries

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A Randomized Controlled Trial of Ethyl Glucuronide-Based Contingency Management for Outpatients With Co-Occurring Alcohol Use Disorders and Serious Mental Illness., Michael G McDonell, Emily Leickly, Sterling McPherson, Jordan Skalisky, Debra Srebnik, Frank Angelo, Roger Vilardaga, Jenny R Nepom, John M Roll, and Richard K Ries

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Neuroinflammatory and cognitive consequences of combined radiation and immunotherapy in a novel preclinical model., Gwendolyn J McGinnis, David Friedman, Kristina H Young, Eileen Ruth S Torres, Charles R Thomas, Michael J Gough, and Jacob Raber

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Secukinumab sustains improvement in signs and symptoms of psoriatic arthritis: 2 year results from the phase 3 FUTURE 2 study., Iain B McInnes, Philip Mease, Christopher T Ritchlin, Proton Rahman, Alice B Gottlieb, Bruce Kirkham, Radhika Kajekar, Eumorphia-Maria Delicha, Luminita Pricop, and Shephard Mpofu

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Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes., James D McKay, Rayjean J Hung, Younghun Han, Xuchen Zong, Robert Carreras-Torres, David C Christiani, Neil E Caporaso, Mattias Johansson, Xiangjun Xiao, Yafang Li, Jinyoung Byun, Alison Dunning, Karen A Pooley, David C Qian, Xuemei Ji, Geoffrey Liu, Maria N Timofeeva, Stig E Bojesen, Xifeng Wu, Loic Le Marchand, Demetrios Albanes, Heike Bickeböller, Melinda C Aldrich, William S Bush, Adonina Tardon, Gad Rennert, M Dawn Teare, John K Field, Lambertus A Kiemeney, Philip Lazarus, Aage Haugen, Stephen Lam, Matthew B Schabath, Angeline S Andrew, Hongbing Shen, Yun-Chul Hong, Jian-Min Yuan, Pier Alberto Bertazzi, Angela C Pesatori, Yuanqing Ye, Nancy Diao, Li Su, Ruyang Zhang, Yonathan Brhane, Natasha Leighl, Jakob S Johansen, Anders Mellemgaard, Walid Saliba, Christopher A Haiman, Lynne R Wilkens, Ana Fernandez-Somoano, Guillermo Fernandez-Tardon, Henricus F M van der Heijden, Jin Hee Kim, Juncheng Dai, Zhibin Hu, Michael P A Davies, Michael W Marcus, Hans Brunnström, Jonas Manjer, Olle Melander, David C Muller, Kim Overvad, Antonia Trichopoulou, Rosario Tumino, Jennifer A Doherty, Matt P Barnett, Chu Chen, Gary E Goodman, Angela Cox, Fiona Taylor, Penella Woll, Irene Brüske, H-Erich Wichmann, Judith Manz, Thomas R Muley, Angela Risch, Albert Rosenberger, Kjell Grankvist, Mikael Johansson, Frances A Shepherd, Ming-Sound Tsao, Susanne M Arnold, Eric B Haura, Ciprian Bolca, Ivana Holcatova, Vladimir Janout, Milica Kontic, Jolanta Lissowska, Anush Mukeria, Simona Ognjanovic, Tadeusz M Orlowski, Ghislaine Scelo, Beata Swiatkowska, David Zaridze, Per Bakke, Vidar Skaug, Shanbeh Zienolddiny, Eric J Duell, Lesley M Butler, Woon-Puay Koh, Yu-Tang Gao, Richard S Houlston, John McLaughlin, Victoria L Stevens, Philippe Joubert, Maxime Lamontagne, David C Nickle, Ma'en Obeidat, Wim Timens, Bin Zhu, Lei Song, Linda Kachuri, María Soler Artigas, Martin D Tobin, Louise V Wain, Thorunn Rafnar, Thorgeir E Thorgeirsson, Gunnar W Reginsson, Kari Stefansson, Dana B Hancock, Laura J Bierut, Margaret R Spitz, Nathan C Gaddis, Sharon M Lutz, Fangyi Gu, Eric O Johnson, Ahsan Kamal, Claudio Pikielny, Dakai Zhu, Sara Lindströem, Xia Jiang, Rachel F Tyndale, Georgia Chenevix-Trench, Jonathan Beesley, Yohan Bossé, Stephen Chanock, Paul Brennan, Maria Teresa Landi, and Christopher I Amos

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Preface., Thomas M McLoughlin, Francis V Salinas, and Laurence C Torsher

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New pathways of treatment for psoriatic arthritis., Philip Mease

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Efficacy and safety of abatacept, a T-cell modulator, in a randomised, double-blind, placebo-controlled, phase III study in psoriatic arthritis., Philip Mease, Alice B Gottlieb, Désirée van der Heijde, Oliver FitzGerald, Alyssa Johnsen, Marleen Nys, Subhashis Banerjee, and Dafna D Gladman

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Tofacitinib or Adalimumab versus Placebo for Psoriatic Arthritis., Philip Mease, Stephen Hall, Oliver FitzGerald, Désirée van der Heijde, Joseph F Merola, Francisco Avila-Zapata, Dorota Cieślak, Daniela Graham, Cunshan Wang, Sujatha Menon, Thijs Hendrikx, and Keith S Kanik

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Clinical Characteristics, Disease Activity, and Patient-Reported Outcomes in Psoriatic Arthritis Patients With Dactylitis or Enthesitis: Results From the Corrona Psoriatic Arthritis/Spondyloarthritis Registry., Philip Mease, Chitra Karki, Jacqueline B Palmer, Carol J Etzel, Arthur Kavanaugh, Christopher T Ritchlin, Wendi Malley, Vivian Herrera, Melody Tran, and Jeffrey D Greenberg

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Prediction and benefits of minimal disease activity in patients with psoriatic arthritis and active skin disease in the ADEPT trial., Philip Mease, Arthur Kavanaugh, Laura C Coates, Iain B McInnes, Maja Hojnik, Ying Zhang, Jaclyn K Anderson, Alexander P Dorr, and Dafna D Gladman

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Changes in Treatment Patterns in Patients with Psoriatic Arthritis Initiating Biologic and Nonbiologic Therapy in a Clinical Registry., Philip Mease, Tamara Lesperance, Mei Liu, David H Collier, Marc Mason, Sabrina Deveikis, and Neil A Accortt

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Performance of 3 Enthesitis Indices in Patients with Peripheral Spondyloarthritis During Treatment with Adalimumab., Philip Mease, Filip Van den Bosch, Joachim Sieper, Yinglin Xia, Aileen L Pangan, and In-Ho Song

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Community network lung cancer screening experience underrepresents medically underserved and geographically remote individuals The International Association for the Study of Lung Ca, AM Meggyesy, Candice L. Wilshire, and See all authors in comments

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Pancreaticoduodenectomy in a patient with previous left ventricular assist device: a case report with specific emphasis on peri-operative logistics., Juan Mejia, Mei Dong, and Okechukwu Ojogho

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P-043 Feasibility of a Multicenter, Collaborative, Longitudinal, Quality Improvement Learning Health System for Adult IBD Care, Gil Melmed, Kelly McCutcheon Adams, Harry Bray, Jessica Caron, Joshua Deitch, Gary Hirschhorn, Michael Jones, Millie Long, Donald Lum, David Rubin, Samir Shah, Jason Hou, Andrew Tinsley, Quin Turner, Ziad Younes, Cynthia Walsh, Ridhima Oberai, Alandra Weaver, Damara Crate, and Corey Siegel

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Timing of PD-1 Blockade Is Critical to Effective Combination Immunotherapy with Anti-OX40., David J Messenheimer, Shawn M. Jensen, Michael E Afentoulis, Keith W Wegman, Zipei Feng, David J Friedman, Michael J. Gough, Walter Urba, and Bernard A Fox

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Curcumin and Turmeric Modulate the Tumor-Promoting Effects of Iron In Vitro., Donald J Messner, Todd Robinson, and Kris V Kowdley

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A global Staphylococcus aureus proteome resource applied to the in vivo characterization of host-pathogen interactions., Stephan Michalik, Maren Depke, Annette Murr, Manuela Gesell Salazar, Ulrike Kusebauch, Zhi Sun, Tanja C Meyer, Kristin Surmann, Henrike Pförtner, Petra Hildebrandt, Stefan Weiss, Laura Marcela Palma Medina, Melanie Gutjahr, Elke Hammer, Dörte Becher, Thomas Pribyl, Sven Hammerschmidt, Eric W Deutsch, Samuel L Bader, Michael Hecker, Robert L Moritz, Ulrike Mäder, Uwe Völker, and Frank Schmidt

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A Two-Biomarker Model Predicts Mortality in the Critically Ill with Sepsis., Carmen Mikacenic, Brenda L Price, Susanna Harju-Baker, D Shane O'Mahony, Cassianne Robinson-Cohen, Frank Radella, William O Hahn, Ronit Katz, David C Christiani, Jonathan Himmelfarb, W Conrad Liles, and Mark M Wurfel

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Effect of Infla-Kine supplementation on the gene expression of inflammatory markers in peripheral mononuclear cells and on C-reactive protein in blood., Nina A Mikirova, Santosh Kesari, Thomas E Ichim, and Neil H Riordan

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Pack-Year Cigarette Smoking History for Determination of Lung Cancer Screening Eligibility. Comparison of the Electronic Medical Record versus a Shared Decision-making Conversation., Hannah E Modin, Joelle T Fathi, Christopher R Gilbert, Candice L. Wilshire, Andrew K Wilson, Ralph W Aye, Alexander S Farivar, Brian E Louie, Eric Vallières, and Jed A Gorden

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Advancement of Surgical Visualization Methods: Comparison Study Between Traditional Microscopic Surgery and a Novel Robotic Optoelectronic Visualization Tool for Spinal Surgery., Marc D Moisi, Kimberly Hoang, R Shane Tubbs, Jeni Page, Christian Fisahn, David Paulson, Shiveindra Jeyamohan, Johnny Delashaw, David Hanscom, Rod J Oskouian, and Jens Chapman

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Posterior arch C-1 screw technique: a cadaveric comparison study., Marc Moisi, Christian Fisahn, Lara Tkachenko, Shiveindra Jeyamohan, Stephen Reintjes, Peter Grunert, Daniel C Norvell, R Shane Tubbs, Jeni Page, David W Newell, Peter Nora, Rod J Oskouian, and Jens R Chapman

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Standardizing terminology for minimally invasive pancreatic resection., Andre L Montagnini, Bård I Røsok, Horacio J Asbun, Jeffrey Barkun, Marc G Besselink, Ugo Boggi, Kevin C P Conlon, Abe Fingerhut, Ho-Seong Han, Paul D Hansen, Melissa E Hogg, Michael L Kendrick, Chinnusamy Palanivelu, Shailesh V Shrikhande, Go Wakabayashi, Herbert Zeh, Charles M Vollmer, and David A Kooby

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The ancient Syrian physician Archigenes and his contributions to neurology and neuroanatomy., Michael James Montalbano, Amit Sharma, Rod J Oskouian, Marios Loukas, and R Shane Tubbs

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Vitamin D, Heidi D Moretti, Vincent J Colucci, and Bradley D Berry

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Incidence, Positional Distribution, Severity, and Time Missed in Medial Collateral Ligament Injuries of the Knee in NCAA Division I Football Athletes., Ali R Motamedi, Anirudh K Gowd, Alireza K Nazemi, Stephen T Gardner, and Caleb J Behrend

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The Effect of Superparamagnetic Iron Oxide Nanoparticle Surface Charge on Antigen Cross-Presentation., Yongbin Mou, Yun Xing, Hongyan Ren, Zhihua Cui, Yu Zhang, Guangjie Yu, Walter J Urba, Qingang Hu, and Hongming Hu

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Systematic Evaluation of Patients Treated With Neurothrombectomy Devices for Acute Ischemic Stroke: Primary Results of the STRATIS Registry., Nils H Mueller-Kronast, Osama O Zaidat, Michael T Froehler, Reza Jahan, Mohammad Ali Aziz-Sultan, Richard P Klucznik, Jeffrey L Saver, Frank R Hellinger, Dileep R Yavagal, Tom L Yao, David S Liebeskind, Ashutosh P Jadhav, Rishi Gupta, Ameer E Hassan, Coleman O Martin, Hormozd Bozorgchami, Ritesh Kaushal, Raul G Nogueira, Ravi H Gandhi, Eric C Peterson, Shervin R Dashti, Curtis A Given, Brijesh P Mehta, Vivek Deshmukh, Sidney Starkman, Italo Linfante, Scott H McPherson, Peter Kvamme, Thomas J Grobelny, Muhammad S Hussain, Ike Thacker, Nirav Vora, Peng Roc Chen, Stephen J Monteith, Robert D Ecker, Clemens M Schirmer, Eric Sauvageau, Alex Abou-Chebl, Colin P Derdeyn, Lucian Maidan, Aamir Badruddin, Adnan H Siddiqui, Travis M Dumont, Abdulnasser Alhajeri, M Asif Taqi, Khaled Asi, Jeffrey Carpenter, Alan Boulos, Gaurav Jindal, Ajit S Puri, Rohan Chitale, Eric M Deshaies, David H Robinson, David F Kallmes, Blaise W Baxter, Mouhammad A Jumaa, Peter Sunenshine, Aniel Majjhoo, Joey D English, Shuichi Suzuki, Richard D Fessler, Josser E Delgado Almandoz, Jerry C Martin, and Diogo C Haussen

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Cellular Signaling Pathways in Insulin Resistance-Systems Biology Analyses of Microarray Dataset Reveals New Drug Target Gene Signatures of Type 2 Diabetes Mellitus., Syed Aun Muhammad, Waseem Raza, Thanh Nguyen, Baogang Bai, Xiaogang Wu, and Jake Chen

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Long-term Outcomes After Autologous Hematopoietic Stem Cell Transplantation for Multiple Sclerosis., Paolo A Muraro, Marcelo Pasquini, Harold L Atkins, James D Bowen, Dominique Farge, Athanasios Fassas, Mark S Freedman, George E Georges, Francesca Gualandi, Nelson Hamerschlak, Eva Havrdova, Vassilios K Kimiskidis, Tomas Kozak, Giovanni L Mancardi, Luca Massacesi, Daniela A Moraes, Richard A Nash, Steven Pavletic, Jian Ouyang, Montserrat Rovira, Albert Saiz, Belinda Simoes, Marek Trnený, Lin Zhu, Manuela Badoglio, Xiaobo Zhong, Maria Pia Sormani, and Riccardo Saccardi

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Management of Hangman's Fractures: A Systematic Review., Hamadi Murphy, Gregory D Schroeder, Weilong J Shi, Christopher K Kepler, Mark F Kurd, Andrew N Fleischman, Frank Kandziora, Jens R Chapman, Lorin M Benneker, and Alexander R Vaccaro

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New migraine with visual disturbance after cryoballoon ablation of atrial fibrillation., Annupreet Nadha and Eric S Williams

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LINE-1 hypomethylation status of circulating cell-free DNA in plasma as a biomarker for colorectal cancer., Yuzo Nagai, Eiji Sunami, Yoko Yamamoto, Keisuke Hata, Satoshi Okada, Koji Murono, Koji Yasuda, Kensuke Otani, Takeshi Nishikawa, Toshiaki Tanaka, Tomomichi Kiyomatsu, Kazushige Kawai, Hiroaki Nozawa, Soichiro Ishihara, Dave S B Hoon, and Toshiaki Watanabe

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Feasibility and Data Quality of the National Spinal Cord Injury Registry of Iran (NSCIR-IR): A Pilot Study., Khatereh Naghdi, Zahra Azadmanjir, Soheil Saadat, Aidin Abedi, Sahar Koohi Habibi, Pegah Derakhshan, Mahdi Safdarian, Shayan Abdollah Zadegan, Abbas Amirjamshidi, Mahdi Sharif-Alhoseini, Jalil Arab Kheradmand, Mahdi Mohammadzadeh, Kazem Zendehdel, Zahra Khazaeipour, Seyed Mahmood Ramak Hashemi, Hooshang Saberi, Kourosh Karimi Yarandi, Seyed Ebrahim Ketabchi, Shahrokh Yousefzadeh-Chabok, Hamid Heidari, Arezo Sotodeh, Khalil Pestei, Zahra Ghodsi, Farideh Sadeghian, Vanessa Noonan, Edward C Benzel, Gerard Oreilly, Jens Chapman, Ellen Merete Hagen, Michael G Fehlings, Alexander R Vaccaro, Morteza Faghih Jooybari, Mohammad Reza Zarei, Mohammad Reza Zafarghandi, Payman Salamati, Saeed Nezareh, Moein Khormali, Mohsen Sadeghi-Naini, Seyed Behzad Jazayeri, Bizhan Aarabi, and Vafa Rahimi-Movaghar

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Strengthening Global Health Outreach Programs Through Pharmacy Services., Vidya Nair, Anthony J Haberstroh, Marilyn Berko, Wayne Rapp, Brittany Fowler, and Kirsten Redborg

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SMARCB1 is required for widespread BAF complex-mediated activation of enhancers and bivalent promoters., Robert T Nakayama, John L Pulice, Alfredo M Valencia, Matthew J McBride, Zachary M McKenzie, Mark A Gillespie, Wai Lim Ku, Mingxiang Teng, Kairong Cui, Robert T Williams, Seth H Cassel, He Qing, Christian J Widmer, George D Demetri, Rafael A Irizarry, Keji Zhao, Jeffrey A Ranish, and Cigall Kadoch

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Transplant with a twist: A pitfall in sonographic diagnosis of renal transplant torsion., Evan Narasimhan, Anne Kennedy, and Jeffrey Campsen

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The semiology of benign focal epilepsy with affective symptoms., Fábio A Nascimento, Márcio A Sotero de Menezes, Cristiane A Simão, Bruno T Takeshita, Samanta F Blattes da Rocha, and Pedro A Kowacs

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High-dose immunosuppressive therapy and autologous HCT for relapsing-remitting MS., Richard A Nash, George J Hutton, Michael K Racke, Uday Popat, Steven M Devine, Kaitlyn C Steinmiller, Linda M Griffith, Paolo A Muraro, Harry Openshaw, Peter H Sayre, Olaf Stuve, Douglas L Arnold, Mark H Wener, George E Georges, Annette Wundes, George H Kraft, and J D Bowen

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Osteoporosis Treatment Efficacy for Men: A Systematic Review and Meta-Analysis., Smita Nayak and Susan L Greenspan

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Sex-specific associations of maternal birthweight with offspring birthweight in the Omega study., Collette N Ncube, Amelia R Gavin, Michelle A Williams, Chunfang Qiu, Tanya K Sorensen, and Daniel A Enquobahrie

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Reply to Dr Kelly et al., Joseph M Neal, Francis V Salinas, and Daniel S Choi

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Impact of Time Between Diagnosis and SLNB on Outcomes in Cutaneous Melanoma., Daniel W Nelson, Stacey Stern, David E Elashoff, Robert Elashoff, John F Thompson, Nicola Mozzillo, Omgo E Nieweg, Harald J Hoekstra, Alistair J Cochran, and Mark B Faries

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Therapeutic Considerations for Antihyperglycemic Agents in Diabetic Kidney Disease., Joshua J Neumiller, Radica Alicic, and Katherine Tuttle

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Regarding "Toward normal birth-but at what cost?", David L Newfield

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Toxoplasma Modulates Signature Pathways of Human Epilepsy, Neurodegeneration & Cancer., Huân M Ngô, Ying Zhou, Hernan Lorenzi, Kai Wang, Taek-Kyun Kim, Yong Zhou, Kamal El Bissati, Ernest Mui, Laura Fraczek, Seesandra V Rajagopala, Craig W Roberts, Fiona L Henriquez, Alexandre Montpetit, Jenefer M Blackwell, Sarra E Jamieson, Kelsey Wheeler, Ian J Begeman, Carlos Naranjo-Galvis, Ney Alliey-Rodriguez, Roderick G Davis, Liliana Soroceanu, Charles Cobbs, Dennis A Steindler, Kenneth Boyer, A Gwendolyn Noble, Charles N Swisher, Peter T Heydemann, Peter Rabiah, Shawn Withers, Patricia Soteropoulos, Leroy Hood, and Rima McLeod

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Utilization of Pharmacists in Addressing Medication Abuse in the Pacific Northwest., Duy Q Nguyen, Brian Chung, Loryn L Osburn, Mark A Della Paolera, and Benjamin Chavez

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Intentional Self-inflicted Burn Injuries: Review of the Literature., Mladen Nisavic, Shamim H Nejad, and Scott R Beach

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Proliferative pilomatricoma of the eyebrow in a 94-year-old patient., Christopher Nyte

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Defining Outcome Measures for Psoriatic Arthritis: A Report from the GRAPPA-OMERACT Working Group., Alexis Ogdie, Maarten de Wit, Kristina Callis Duffin, Willemina Campbell, Jeffrey Chau, Laura C Coates, Lihi Eder, Musaab Elmamoun, Oliver FitzGerald, Dafna D Gladman, Niti Goel, Jana James, Umut Kalyoncu, John Latella, Chris Lindsay, Philip Mease, Denis O'Sullivan, Ingrid Steinkoenig, Vibeke Strand, William Tillett, and Ana-Maria Orbai

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Comparing Quality of Life in Cervical Spondylotic Myelopathy with Other Chronic Debilitating Diseases Using the Short Form Survey 36-Health Survey., Taemin Oh, Renaud Lafage, Virginie Lafage, Themistocles Protopsaltis, Vincent Challier, Christopher Shaffrey, Han Jo Kim, Paul Arnold, Jens R Chapman, Frank Schwab, Eric Massicotte, Tim Yoon, Shay Bess, Michael Fehlings, Justin Smith, and Christopher Ames

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Progress on the HUPO Draft Human Proteome: 2017 Metrics of the Human Proteome Project., Gilbert S Omenn, Lydie Lane, Emma K Lundberg, Christopher M Overall, and Eric W Deutsch

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The diagnostic challenge of low-grade ductal carcinoma in situ., Tracy Onega, Donald L Weaver, Paul D Frederick, Kimberly H Allison, Anna N A Tosteson, Patricia A Carney, Berta M Geller, Gary M Longton, Heidi D Nelson, Natalia V Oster, Margaret S Pepe, and Joann G Elmore

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Spine Trauma-What Are the Current Controversies?, Cumhur Oner, Shanmuganathan Rajasekaran, Jens R Chapman, Michael G Fehlings, Alexander R Vaccaro, Gregory D Schroeder, Said Sadiqi, and James Harrop

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Updating the Psoriatic Arthritis (PsA) Core Domain Set: A Report from the PsA Workshop at OMERACT 2016., Ana-Maria Orbai, Maarten de Wit, Philip Mease, Kristina Callis Duffin, Musaab Elmamoun, William Tillett, Willemina Campbell, Oliver FitzGerald, Dafna D Gladman, Niti Goel, Laure Gossec, Pil Hoejgaard, Ying Ying Leung, Chris Lindsay, Vibeke Strand, Désirée M van der Heijde, Bev Shea, Robin Christensen, Laura Coates, Lihi Eder, Neil McHugh, Umut Kalyoncu, Ingrid Steinkoenig, and Alexis Ogdie

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RRx-001: a systemically non-toxic M2-to-M1 macrophage stimulating and prosensitizing agent in Phase II clinical trials., Bryan Oronsky, Ramasamy Paulmurugan, Kira Foygel, Jan Scicinski, Susan J Knox, Donna Peehl, Hongjuan Zhao, Shoucheng Ning, Pedro Cabrales, Thomas A Summers, Tony R Reid, William L Fitch, Michelle M Kim, Jane B Trepel, Min-Jung Lee, Santosh Kesari, Nacer D Abrouk, Regina M Day, Arnold Oronsky, Carolyn M Ray, and Corey A Carter

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Risk of gestational diabetes mellitus in relation to maternal dietary calcium intake., Citlalli Osorio-Yáñez, Chunfang Qiu, Bizu Gelaye, Daniel A Enquobahrie, and Michelle A Williams

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The prognostic importance of scalp location in primary head and neck melanoma., Junko Ozao-Choy, Daniel W Nelson, Jason Hiles, Stacey L Stern, Jeong Lim Yoon, Myung Shin Sim, and Mark Faries