Providence research from Washington locations.

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Submissions from 2022

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Is DIA proteomics data FAIR? Current data sharing practices, available bioinformatics infrastructure and recommendations for the future., Andrew R Jones, Eric W Deutsch, and Juan Antonio Vizcaíno

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Validation of the Foot and Ankle Outcome Score for Use in Infracalcaneal Heel Pain., Alisha Joshi, Christopher Collazo, Zachary Laidley, Erin E Klein, Lowell Weil, Matthew D Sorensen, and Adam E Fleischer

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The Novel Conduit: Challenges of Esophagectomy After Bariatric Surgery., Michael Jureller, Shankar I Logarajah, Travis Allen Van Meter, Housam Osman, John Jay, Maitham Moslim, Ralph W Aye, and D Rohan Jeyarajah

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Early Experience With New Femoral and Tibial Cones in Revision Total Knee Arthroplasty: A Case Series., Michael E Kahan, Joshua E Drumm, Zhongming Chen, Arthur L Malkani, Michael A Mont, Ronald E Delanois, and James Nace

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Profiling the Human Phosphoproteome to Estimate the True Extent of Protein Phosphorylation., Anton Kalyuzhnyy, Patrick A Eyers, Claire E Eyers, Emily Bowler-Barnett, Maria J Martin, Zhi Sun, Eric W Deutsch, and Andrew R Jones

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The validity, responsiveness, and score interpretation of the PROMISnq Physical Function - Multiple Sclerosis 15a short form in multiple sclerosis., Paul Kamudoni, Dagmar Amtmann, Jeffrey Johns, Karon F Cook, Rana Salem, Sam Salek, Jana Raab, Rod Middleton, P Repovic, Kevin N Alschuler, Gloria von Geldern, Annette Wundes, Amy Barrett, Oyebimpe Olayinka-Amao, and Christian Henke

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Fatty Kidney: A Possible Future for Chronic Kidney Disease Research., Mehmet Kanbay, Sidar Copur, Atalay Demiray, Alan A Sag, Adrian Covic, Alberto Ortiz, and Katherine Tuttle

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Cardiorenal Metabolic Consequences of Nighttime Snacking: Is it an Innocent Eating Behavior?, Mehmet Kanbay, Sidar Copur, Atalay Demiray, and Katherine Tuttle

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The risk for chronic kidney disease in metabolically healthy obese patients: A systematic review and meta-analysis., Mehmet Kanbay, Sidar Copur, Dimitrie Siriopol, Abdullah B Yildiz, Metehan Berkkan, Katherine Tuttle, and Carmine Zoccali

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Exploring Perinatal Nursing Care for Opioid Use Disorder: Knowledge, Stigma, and Compassion., Ira Kantrowitz-Gordon, Cynthia Price, Vania Rudolf, Georgia Downey, and Kelsey Castagnola

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Tyrosine kinase-altered spindle cell neoplasms with EGFR internal tandem duplications., Erica Kao, Navin Pinto, Angela Trobaugh-Lotrario, Gail H Deutsch, Yu Wu, Wenjing Wang, Erin R Rudzinski, and Yajuan J Liu

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PCM1-JAK2 Fusion Tyrosine Kinase Gene-Related Neoplasia: A Systematic Review of the Clinical Literature., Henry G Kaplan, Ruyun Jin, Carlo Bifulco, James M Scanlan, and David R Corwin

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Trastuzumab therapy duration in HER2-positive de novo metastatic breast cancer: 1999-2018, Henry Kaplan, Judith A. Malmgren, Boya Guo, and Mary K. Atwood

Reszinate—A Phase 1/2 Randomized Clinical Trial of Zinc and Resveratrol Utilizing Home Patient-Obtained Nasal and Saliva Viral Sampling, Henry Kaplan, Kai Wang, Kimberly M. Reeves, James Scanlan, Christopher C. Nunn, Douglas A. Kieper, Joshua L. Mark, Inyoul Lee, Rachel Liu, Ruyun Jin, Michael J. Bolton, and Jason D. Goldman

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Treatment of nonsurgical refractory back pain with high-frequency spinal cord stimulation at 10 kHz: 12-month results of a pragmatic, multicenter, randomized controlled trial., Leonardo Kapural, Jessica Jameson, Curtis Johnson, Daniel Kloster, Aaron Calodney, Peter Kosek, Julie Pilitsis, Markus Bendel, Erika Petersen, Chengyuan Wu, Taissa Cherry, Shivanand P Lad, Cong Yu, Dawood Sayed, Johnathan Goree, Mark K Lyons, Andrew Sack, Diana Bruce, Frances Rubenstein, Rose Province-Azalde, David Caraway, and Naresh P Patel

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Programmed cell death detection methods: a systematic review and a categorical comparison., Sana Kari, Kumar Subramanian, Ilenia Agata Altomonte, Akshaya Murugesan, Olli Yli-Harja, and Meenakshisundaram Kandhavelu

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Government Regulation and Percutaneous Coronary Intervention Volume, Access and Outcomes: Insights From the Washington State Cardiac Care Outcomes Assessment Program., Akash Kataruka, Charles C Maynard, Ravi S Hira, Larry Dean, Todd Dardas, Hitinder Gurm, Josiah Brown, Michael Ring, and Jacob A Doll

Implementing Goal-Directed Medical Therapies for Diabetic Kidney Disease: The Garabed Eknoyan MD, Endowed Lectureship, Tuttle Katherine

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A Testable Theory for the Emergence of the Classical World., Stuart Kauffman and Sudip Patra

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KDIGO 2022 Clinical Practice Guideline for Diabetes Management in Chronic Kidney Disease., Kidney Disease: Improving Global Outcomes (KDIGO) Diabetes Work Group and Katherine Tuttle

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Role of Endoscopic Retrograde Cholangiopancreatography in the Diagnosis and Management of Cholestatic Liver Diseases., Tara Keihanian, Monique T Barakat, Sooraj Tejaswi, Rajnish Mishra, Christopher J Carlson, John J Brandabur, and Mohit Girotra

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Identification of the Collagen Types Essential for Mammalian Breast Acinar Structures., Chandler R Keller, Kelsey F Ruud, Steve R Martinez, and Weimin Li

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Practice trends for perioperative intravesical chemotherapy in upper tract urothelial carcinoma: Low but increasing utilization during minimally invasive nephroureterectomy., Alexander P Kenigsberg, Gianpaolo Carpinito, Samuel A Gold, Xiaosong Meng, Alireza Ghoreifi, Hooman Djaladat, Andrea Minervini, Marcus Jamil, Firas Abdollah, Jason M Farrow, Chandru Sundaram, Robert Uzzo, Matteo Ferro, Margaret Meagher, Ithaar Derweesh, Zhenjie Wu, James R Porter, Andrew Katims, Reza Mehrazin, Alex Mottrie, Giuseppe Simone, Adam C Reese, Daniel D Eun, Amit Satish Bhattu, Mark L Gonzalgo, Umberto Carbonara, Riccardo Autorino, and Vitaly Margulis

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Early Response of Primary Care Practices to COVID-19 Pandemic., Gina Keppel, Allison M Cole, Mary Ramsbottom, Stuti Nagpal, Jaime Hornecker, Claire Thomson, Viet Nguyen, and Laura-Mae Baldwin

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Early Local Therapy for the Primary Site in De Novo Stage IV Breast Cancer: Results of a Randomized Clinical Trial (EA2108)., Seema A Khan, Fengmin Zhao, Lori J Goldstein, David Cella, Mark Basik, Mehra Golshan, Thomas B Julian, Barbara A Pockaj, Christine A Lee, Wajeeha Razaq, Joseph A Sparano, Gildy V Babiera, Irene A Dy, Sarika Jain, Paula Silverman, Carla S Fisher, Amye J Tevaarwerk, Lynne I Wagner, and George W Sledge

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An atypical clinical course of a 71-year-old man with right arm weakness and ataxia., Pravin Khemani, Michael Elliott, and Todd Levine

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KDIGO 2022 Clinical Practice Guideline for Diabetes Management in Chronic Kidney Disease., Kidney Disease: Improving Global Outcomes (KDIGO) Diabetes Work Group and Katherine Tuttle

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Quality of life after long-term biochemical control of acromegaly., Allison Kimball, Laura E Dichtel, Kevin C J Yuen, Whitney W Woodmansee, Melanie S Haines, Lisa B Nachtigall, Brooke Swearingen, Pamela Jones, Nicholas A Tritos, Julie L Sharpless, Ursula B Kaiser, Anu Gerweck, and Karen K Miller

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Clinical Factors and Outcomes When Real-World Heart Teams Overruled STS Risk Scores in TAVR Cases., Jackson M King, Morgan T Black, Ruyun Jin, Gary L Grunkemeier, Branden Reynolds, Brydan Curtis, Robert W. Hodson, Erika A Strehl, Sameer Gafoor, Matthew Forrester, Emily J Cox, and Michael Ring

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Harm Reduction For STHC Patients With Opioid Use Disorder, Michael P. Kinney and Amy G Burns

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Efficacy of secukinumab on dactylitis in patients with active psoriatic arthritis from the FUTURE 5 study., Bruce Kirkham, Peter Nash, Delia Reina, Sandra Navarra, Erhard Quebe-Fehling, Corine Gaillez, Carlos Sastre, and Philip Mease

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Changes in Distensibility Index During an Incremental POEM Myotomy., T B Knowles, Anee Sophia Jackson, Shu-Ching Chang, Drew B Schembre, Alexander S Farivar, Ralph W Aye, and Brian Louie

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The timed 25-foot walk is a more sensitive outcome measure than the EDSS for PPMS trials: an analysis of the PROMISE clinical trial dataset., Marcus W Koch, Jop Mostert, P Repovic, J D Bowen, Jacynthe Comtois, Eva Strijbis, Bernard Uitdehaag, and Gary Cutter

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The nine hole peg test as an outcome measure in progressive MS trials., Marcus W Koch, P Repovic, Jop Mostert, J D Bowen, Jacynthe Comtois, Eva Strijbis, Bernard Uitdehaag, and Gary Cutter

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Outcomes of endoscopic retrograde cholangiography and percutaneous transhepatic biliary drainage in liver transplant recipients with a Roux-en-Y biliary-enteric anastomosis., Divyanshoo Rai Kohli, Bashar A Aqel, Nicole L Segaran, M Edwyn Harrison, Norio Fukami, Douglas O Faigel, Adyr Moss, Amit Mathur, Winston Hewitt, Nitin Katariya, and Rahul Pannala

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Comparative Accuracy of Endosonographic shear wave elastography and Transcutaneous Liver Stiffness Measurement: A pilot study., Divyanshoo R Kohli, Daniel Mettman, Nevene Andraws, Erin Haer, Jaime Porter, Ozlem Ulusurac, Steven Ullery, Madhav Desai, Mohammad S Siddiqui, and Prateek Sharma

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Direct Percutaneous Endoscopic Gastrostomy Versus Radiological Gastrostomy in Patients Unable to Undergo Transoral Endoscopic Pull Gastrostomy., Divyanshoo R Kohli, Craig Smith, Omer Chaudhry, Madhav Desai, Dion DePaolis, and Prateek Sharma

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Interleukin-6 and Cardiovascular and Kidney Outcomes in Patients With Type 2 Diabetes: New Insights From CANVAS., Akihiko Koshino, Meir Schechter, Taha Sen, Priya Vart, Brendon L Neuen, Bruce Neal, Clare Arnott, Vlado Perkovic, Paul M Ridker, Katherine R Tuttle, Michael K Hansen, and Hiddo J L Heerspink

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Emergency Medicine in India - First Step towards Capacity Building., Arva Koushik, Aiman Perween Afsar, Tarun Kumar Suvvari, Lokesh Edara, Arunachalam Einstein, and Ashima Sharma

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Stress Injuries of the Knee., Emily Kraus, Katherine Rizzone, Mahala Walker, Naomi Brown, Japsimran Kaur, Danielle Magrini, Jayden Glover, and Eric Nussbaum

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Factors impacting genomic testing rates among epithelial ovarian cancer patients across a large community-based healthcare system, Nicole M. Kretzer, Christopher J. Darus, Nancy Biery, Roshanthi Weerasinghe, Grace Li, Ann Vita, Shwetha Pindikuri, Amy S. Parrish, Charles W Drescher, and Fernanda B. Musa

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Frequency of homologous recombination deficiency in a large community-based cohort of epithelial ovarian cancer cases, Nicole M. Kretzer, Fernanda B. Musa, Christopher Darus, Nancy Biery, Roshanthi Weerasinghe, Grace Li, Ann Vita, Shwetha Pindikuri, Amy S. Parrish, and Charles W Drescher

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Patterns of genomic testing for epithelial ovarian cancer across a large community-based health care network- a real world experience, Nicole M. Kretzer, Fernanda B. Musa, Christopher Darus, Nancy Biery, Roshanthi Weerasinghe, Grace Li, Ann Vita, Shwetha Pindikuri, Amy S. Parrish, and Charles W Drescher

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Racial and Ethnic Disparities in Acute Care Utilization Among Patients With Glomerular Disease., Jill R Krissberg, Michelle M O'Shaughnessy, Abigail R Smith, Margaret E Helmuth, Salem Almaani, Diego H Aviles, Kaye E Brathwaite, Yi Cai, Daniel Cattran, Rasheed Gbadegesin, Dorey A Glenn, Larry A Greenbaum, Sandra Iragorri, Koyal Jain, Myda Khalid, Jason Kidd, Jeffrey Kopp, Richard Lafayette, Jerome C Lane, Francesca Lugani, Jordan G Nestor, Rulan S Parekh, Kimberly Reidy, David T Selewski, Christine B Sethna, C John Sperati, Katherine Tuttle, Katherine Twombley, Tetyana L Vasylyeva, Donald J Weaver, Scott E Wenderfer, Keisha Gibson, and CureGN Consortium

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Sustained postoperative plasma elevations of plasminogen activator inhibitor-1 following minimally invasive colorectal cancer resection., H M C Shantha Kumara, Poppy Addison, Dasuni N Gamage, Erica Pettke, Abhinit Shah, Xiaohong Yan, Vesna Cekic, and Richard L Whelan

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Using machine learning to predict internal rotation after anatomic and reverse total shoulder arthroplasty., Vikas Kumar, Bradley S Schoch, Christine Allen, Steve Overman, Ankur Teredesai, William Aibinder, Moby Parsons, Jonathan Watling, Jia-Wei Kevin Ko, Bruno Gobbato, Thomas Throckmorton, Howard Routman, and Christopher Roche

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Evolution of the AO Spine Sacral and Pelvic Classification System: a systematic review., Barry Ting Sheen Kweh, Jin W Tee, F Cumhur Oner, Klaus J Schnake, Emiliano N Vialle, Frank Kanziora, Shanmuganathan Rajasekaran, Marcel Dvorak, Jens R Chapman, Lorin M Benneker, Gregory Schroeder, and Alexander R Vaccaro

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The role of adjuvant chemotherapy in the management of acute promyelocytic leukemia differentiation syndrome., Dominic LaBella, Samuel Regan, Heiko Konig, Daniel N Egan, Neil Bailey, Raya Mawad, Morgan Gilbert, John M Pagel, and Jeffrey J Pu

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Radiographic Characteristics of Cervical Deformity (CD) Using a Discriminant Analysis: The Value of Extension Radiographs., Renaud Lafage, Sohrab Virk, Jonathan Elysee, Peter Passias, Christopher Ames, Robert A Hart, Christopher Shaffrey, Gregory Mundis, Themistocles Protopsaltis, Munish Gupta, Eric Klineberg, Douglas Burton, Frank Schwab, Virginie Lafage, and ISSG

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Eligibility for COPD Clinical Trials of Inhaled Triple Therapy: Analysis of the Subpopulations and Intermediate Outcomes in COPD Study (SPIROMICS), Allison A Lambert and See full list of authors in comments

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The AO spine upper cervical injury classification system: Do work setting or trauma center affiliation affect classification accuracy or reliability?, Mark J Lambrechts, Gregory D Schroeder, Brian A Karamian, Jose A Canseco, Richard Bransford, Cumhur Oner, Lorin M Benneker, Frank Kandziora, Rajasekaran Shanmuganathan, Rishi Kanna, Andrei F Joaquim, Jens R Chapman, Emiliano Vialle, Mohammad El-Sharkawi, Marcel Dvorak, Klaus Schnake, Christopher K Kepler, and Alexander R Vaccaro

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Global Validation of the AO Spine Upper Cervical Injury Classification: Geographic Region Affects Reliability and Reproducibility., Mark J Lambrechts, Gregory D Schroeder, Brian A Karamian, Jose A Canseco, Richard Bransford, Cumhur Oner, Lorin M Benneker, Frank Kandziora, Rajasekaran Shanmuganathan, Rishi Kanna, Andrei F Joaquim, Jens R Chapman, Emiliano Vialle, Mohammad El-Sharkawi, Marcel Dvorak, Klaus Schnake, Christopher K Kepler, Alexander R Vaccaro, and AO Spine Upper Cervical Injury Classification International Members

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Safety and efficacy of HSP90 inhibitor ganetespib for neoadjuvant treatment of stage II/III breast cancer., Julie E Lang, Andres Forero-Torres, Douglas Yee, Christina Yau, Denise Wolf, John Park, Barbara A Parker, A Jo Chien, Anne M Wallace, Rashmi Murthy, Kathy S Albain, Erin D Ellis, Heather Beckwith, Barbara B Haley, Anthony D Elias, Judy C Boughey, Rachel L Yung, Claudine Isaacs, Amy S Clark, Hyo S Han, Rita Nanda, Qamar J Khan, Kristen K Edmiston, Erica Stringer-Reasor, Elissa Price, Bonnie Joe, Minetta C Liu, Lamorna Brown-Swigart, Emanuel F Petricoin, Julia D Wulfkuhle, Meredith Buxton, Julia L Clennell, Ashish Sanil, Scott Berry, Smita M Asare, Amy Wilson, Gillian L Hirst, Ruby Singhrao, Adam L Asare, Jeffrey B Matthews, Michelle Melisko, Jane Perlmutter, Hope S Rugo, W Fraser Symmans, Laura J van 't Veer, Nola M Hylton, Angela M DeMichele, Donald A Berry, and Laura J Esserman

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Epidemiology of interstitial lung disease in patients with metastatic breast cancer at baseline and after treatment with HER2-directed therapy: a real-world data analysis., Jeanna Wallenta Law, Alicyn Campbell, Colin Weller, Colden Johanson, Ronda Broome, Elisabeth Piault, Monika Izano, Andrew Schrag, Mary Tran, Thomas D Brown, and Henry G Kaplan

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Real-World Treatment Patterns and Clinical Effectiveness of Palbociclib Plus an Aromatase Inhibitor as First-Line Therapy in Advanced/Metastatic Breast Cancer: Analysis from the US Syapse Learning Health Network., Jeanna Wallenta Law, Debanjali Mitra, Henry G Kaplan, Tamuno Alfred, Adam M Brufsky, Birol Emir, Haley McCracken, Xianchen Liu, Ronda G Broome, Chenan Zhang, Caroline DiCristo, and Connie Chen

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More autopsy studies are needed to understand the pathogenesis of severe COVID-19., Scott P Layne, Kathie-Anne Walters, John C Kash, and Jeffery K Taubenberger

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Proteomics Standards Initiative's ProForma 2.0: Unifying the Encoding of Proteoforms and Peptidoforms., Richard D LeDuc, Eric W Deutsch, Pierre-Alain Binz, Ryan T Fellers, Anthony J Cesnik, Joshua A Klein, Tim Van Den Bossche, Ralf Gabriels, Arshika Yalavarthi, Yasset Perez-Riverol, Jeremy Carver, Wout Bittremieux, Shin Kawano, Benjamin Pullman, Nuno Bandeira, Neil L Kelleher, Paul M Thomas, and Juan Antonio Vizcaíno

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Diabetic Retinopathy and Dementia Association, Beyond Diabetes Severity., Cecilia S Lee, Chloe Krakauer, Yu-Ru Su, Rod Walker, Marian Blazes, Susan M McCurry, J D Bowen, Wayne C McCormick, Aaron Y Lee, Edward Boyko, Ann O'Hare, Eric B Larson, and Paul K Crane

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Cediranib in combination with olaparib in patients without a germline BRCA1/2 mutation and with recurrent platinum-resistant ovarian cancer: Phase IIb CONCERTO trial., Jung-Min Lee, Richard G Moore, Sharad Ghamande, Min Park, John P Diaz, Julia Chapman, James Kendrick, Brian M Slomovitz, Krishnansu S Tewari, Elizabeth S Lowe, Tsveta Milenkova, Sanjeev Kumar, Mike Dymond, Jessica Brown, and Joyce F Liu

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Recent Advances in RNA Therapy and Its Carriers to Treat the Single-Gene Neurological Disorders., Ming-Jen Lee, Inyoul Lee, and Kai Wang

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Daptomycin-Resistant Enterococcus Bacteremia Is Associated With Prior Daptomycin Use and Increased Mortality After Liver Transplantation, Rachael A Lee, Jason D Goldman, Ghady Haidar, Jessica Lewis, Sana Arif, Jonathan Hand, Ricardo M La Hoz, Stephanie Pouch, Eric Holaday, Heather Clauss, Keith S Kaye, and Anoma Nellore

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P2Y1 agonist HIC in combination with androgen receptor inhibitor abiraterone acetate impairs cell growth of prostate cancer., Hien Thi Thu Le, Akshaya Murugesan, Nuno R Candeias, Thiyagarajan Ramesh, Olli Yli-Harja, and Meenakshisundaram Kandhavelu

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Decompression only versus fusion in octogenarians with spinal epidural abscesses: early complications, clinical and radiological outcome with 2-year follow-up., Pavlina Lenga, Gelo Gülec, Awais Akbar Bajwa, Mohammed Issa, Rod J Oskouian, Jens R Chapman, Karl Kiening, Andreas W Unterberg, and Basem Ishak

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Radiological Features in Type II Odontoid Fractures in Older Adults After High- and Low-Energy Trauma., Pavlina Lenga, Mohammed Issa, Lennart Krull, Karl Kiening, Andreas W Unterberg, Till Schneider, Rod J Oskouian, Jens R Chapman, and Basem Ishak

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Healthcare consumption among subjects with otitis media undergoing middle ear surgery-analysis of cost drivers., Aaran T Lewis, Douglas D Backous, Byung Yoon Choi, Rafael Jaramillo, Kelvin Kong, Thomas Lenarz, Jaydip Ray, Alok Thakar, Krister Järbrink, and Myrthe K S Hol

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Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial., Linda M Liau, Keyoumars Ashkan, Steven Brem, Jian L Campian, John E Trusheim, Fabio M Iwamoto, David D Tran, George Ansstas, Charles S Cobbs, Jason A Heth, Michael E Salacz, Stacy D'Andre, Robert D Aiken, Yaron A Moshel, Joo Y Nam, Clement P Pillainayagam, Stephanie A Wagner, Kevin A Walter, Rekha Chaudary, Samuel A Goldlust, Ian Y Lee, Daniela A Bota, Heinrich Elinzano, Jai Grewal, Kevin Lillehei, Tom Mikkelsen, Tobias Walbert, Steven Abram, Andrew J Brenner, Matthew G Ewend, Simon Khagi, Darren S Lovick, Jana Portnow, Lyndon Kim, William G Loudon, Nina L Martinez, Reid C Thompson, David E Avigan, Karen L Fink, Francois J Geoffroy, Pierre Giglio, Oleg Gligich, Dietmar Krex, Scott M Lindhorst, Jose Lutzky, Hans-Jörg Meisel, Minou Nadji-Ohl, Lhagva Sanchin, Andrew Sloan, Lynne P Taylor, Julian K Wu, Erin M Dunbar, Arnold B Etame, Santosh Kesari, David Mathieu, David E Piccioni, David S Baskin, Michel Lacroix, Sven-Axel May, Pamela Z New, Timothy J Pluard, Steven A Toms, Victor Tse, Scott Peak, John L Villano, James D Battiste, Paul J Mulholland, Michael L Pearlman, Kevin Petrecca, Michael Schulder, Robert M Prins, Alton L Boynton, and Marnix L Bosch

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Successful endovascular treatment of abdominal aortic rupture secondary to bacillus Calmette-Guérin vaccine., Andrew E Liechty, Albert Pacifico, and Peter Brant-Zawadzki

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A Multimodal Pain Management Strategy for Burn Patients., Kara L Liechty, Kelly Shields, Emily Ogden, Niknam Eshraghi, Michelle Dedeo, and Pamela Bishop

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The Impact of Preoperative Breast Characteristics on Immediate Breast Reconstruction Complications: A Multivariate analysis of Tissue Expander and Autologous Reconstruction, Jeffrey N. Li, Sumeer S. Teotia, and Nicholas T. Haddock

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KIR + CD8 + T cells suppress pathogenic T cells and are active in autoimmune diseases and COVID-19, Jing Li, Maxim Zaslavsky, Yapeng Su, Jing Guo, Michael J Sikora, Vincent van Unen, Asbjørn Christophersen, Shin-Heng Chiou, Liang Chen, Jiefu Li, Xuhuai Ji, Julie Wilhelmy, Alana M McSween, Brad A Palanski, Venkata Vamsee Aditya Mallajosyula, Nathan A Bracey, Gopal Krishna R Dhondalay, Kartik Bhamidipati, Joy Pai, Lucas B Kipp, Jeffrey E Dunn, Stephen L Hauser, Jorge R Oksenberg, Ansuman T Satpathy, William H Robinson, Cornelia L Dekker, Lars M Steinmetz, Chaitan Khosla, Paul J Utz, Ludvig M Sollid, Yueh-Hsiu Chien, James R Heath, Nielsen Q Fernandez-Becker, Kari C Nadeau, Naresha Saligrama, and Mark M Davis

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Randomized Comparison of Transcatheter Edge-to-Edge Repair for Degenerative Mitral Regurgitation in Prohibitive Surgical Risk Patients., D Scott Lim, Robert L Smith, Linda D Gillam, Firas Zahr, Scott Chadderdon, Raj Makkar, Ralph Stephan von Bardeleben, Robert M Kipperman, Andrew N Rassi, Molly Szerlip, Scott Goldman, Ignacio Inglessis-Azuaje, Pradeep Yadav, Philipp Lurz, Charles J Davidson, Mubashir Mumtaz, Hemal Gada, Saibal Kar, Susheel K Kodali, Roger Laham, William Hiesinger, Neil P Fam, Mirjam Keßler, William W O'Neill, Brian Whisenant, Chad Kliger, Samir Kapadia, Volker Rudolph, Joseph Choo, James Hermiller, Michael A Morse, Niklas Schofer, Sameer Gafoor, Azeem Latib, Konstantinos Koulogiannis, Leo Marcoff, and Jörg Hausleiter

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Prevalence of SGLT2i and GLP1RA use among US adults with type 2 diabetes., Christine P Limonte, Yoshio N Hall, Subbulaxmi Trikudanathan, Katherine Tuttle, Irl B Hirsch, Ian H de Boer, and Leila R Zelnick

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Addendum: Transcriptomics and proteomics reveal two waves of translational repression during the maturation of malaria parasite sporozoites., Scott E Lindner, Kristian E Swearingen, Melanie J Shears, Aswathy Sebastian, Michael P Walker, Erin N Vrana, Kevin J Hart, Allen M Minns, Istvan Albert, Photini Sinnis, Robert L Moritz, and Stefan H I Kappe

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Multi-Scalar Data Integration Links Glomerular Angiopoietin-Tie Signaling Pathway Activation With Progression of Diabetic Kidney Disease., Jiahao Liu, Viji Nair, Yi-Yang Zhao, Dong-Yuan Chang, Christine Limonte, Nisha Bansal, Damian Fermin, Felix Eichinger, Emily C Tanner, Keith A Bellovich, Susan Steigerwalt, Zeenat Bhat, Jennifer J Hawkins, Lalita Subramanian, Sylvia E Rosas, John R Sedor, Miguel A Vasquez, Sushrut S Waikar, Markus Bitzer, Subramaniam Pennathur, Frank C Brosius, Ian De Boer, Min Chen, Matthias Kretzler, Wenjun Ju, Kidney Precision Medicine Project and Michigan Translational Core C-PROBE Investigator Group, and Katherine Tuttle

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Genome-wide interaction analysis identified low-frequency variants with sex disparity in lung cancer risk., Yafang Li, Xiangjun Xiao, Jianrong Li, Jinyoung Byun, Chao Cheng, Yohan Bossé, James McKay, Demetrios Albanes, Stephen Lam, Adonina Tardon, Chu Chen, Stig E Bojesen, Maria T Landi, Mattias Johansson, Angela Risch, Heike Bickeböller, H-Erich Wichmann, David C Christiani, Gad Rennert, Susanne Arnold, Gary E Goodman, John K Field, Michael P A Davies, Sanjay S Shete, Loic Le Marchand, Olle Melander, Hans Brunnström, Geoffrey Liu, Rayjean J Hung, Angeline S Andrew, Lambertus A Kiemeney, Hongbing Shen, Ryan Sun, Shan Zienolddiny, Kjell Grankvist, Mikael Johansson, Neil Caporaso, Dawn M Teare, Yun-Chul Hong, Philip Lazarus, Matthew B Schabath, Melinda C Aldrich, Ann G Schwartz, Ivan Gorlov, Kristen Purrington, Ping Yang, Yanhong Liu, Younghun Han, Joan E Bailey-Wilson, Susan M Pinney, Diptasri Mandal, James C Willey, Colette Gaba, Paul Brennan, Christopher I Amos, and INTEGRAL-ILCCO lung cancer consortium

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Author Correction: Comparative and demographic analysis of orang-utan genomes., Devin P Locke, LaDeana W Hillier, Wesley C Warren, Kim C Worley, Lynne V Nazareth, Donna M Muzny, Shiaw-Pyng Yang, Zhengyuan Wang, Asif T Chinwalla, Pat Minx, Makedonka Mitreva, Lisa Cook, Kim D Delehaunty, Catrina Fronick, Heather Schmidt, Lucinda A Fulton, Robert S Fulton, Joanne O Nelson, Vincent Magrini, Craig Pohl, Tina A Graves, Chris Markovic, Andy Cree, Huyen H Dinh, Jennifer Hume, Christie L Kovar, Gerald R Fowler, Gerton Lunter, Stephen Meader, Andreas Heger, Chris P Ponting, Tomas Marques-Bonet, Can Alkan, Lin Chen, Ze Cheng, Jeffrey M Kidd, Evan E Eichler, Simon White, Stephen Searle, Albert J Vilella, Yuan Chen, Paul Flicek, Jian Ma, Brian Raney, Bernard Suh, Richard Burhans, Javier Herrero, David Haussler, Rui Faria, Olga Fernando, Fleur Darré, Domènec Farré, Elodie Gazave, Meritxell Oliva, Arcadi Navarro, Roberta Roberto, Oronzo Capozzi, Nicoletta Archidiacono, Giuliano Della Valle, Stefania Purgato, Mariano Rocchi, Miriam K Konkel, Jerilyn A Walker, Brygg Ullmer, Mark A Batzer, Arian F A Smit, Robert Hubley, Claudio Casola, Daniel R Schrider, Matthew W Hahn, Victor Quesada, Xose S Puente, Gonzalo R Ordoñez, Carlos López-Otín, Tomas Vinar, Brona Brejova, Aakrosh Ratan, Robert S Harris, Webb Miller, Carolin Kosiol, Heather A Lawson, Vikas Taliwal, André L Martins, Adam Siepel, Arindam RoyChoudhury, Xin Ma, Jeremiah Degenhardt, Carlos D Bustamante, Ryan N Gutenkunst, Thomas Mailund, Julien Y Dutheil, Asger Hobolth, Mikkel H Schierup, Oliver A Ryder, Yuko Yoshinaga, Pieter J de Jong, George M Weinstock, Jeffrey Rogers, Elaine R Mardis, Richard A Gibbs, and Richard K Wilson

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Commentary: The forgotten nodal station in esophageal cancer., Brian Louie

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A Comprehensive Evaluation of Consensus Spectrum Generation Methods in Proteomics., Xiyang Luo, Wout Bittremieux, Johannes Griss, Eric W Deutsch, Timo Sachsenberg, Lev I Levitsky, Mark V Ivanov, Julia A Bubis, Ralf Gabriels, Henry Webel, Aniel Sanchez, Mingze Bai, Lukas Käll, and Yasset Perez-Riverol

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A user-friendly tool for cloud-based whole slide image segmentation with examples from renal histopathology., Brendon Lutnick, David Manthey, Jan U Becker, Brandon Ginley, Katharina Moos, Jonathan E Zuckerman, Luis Rodrigues, Alexander J Gallan, Laura Barisoni, Charles E Alpers, Xiaoxin X Wang, Komuraiah Myakala, Bryce A Jones, Moshe Levi, Jeffrey B Kopp, Teruhiko Yoshida, Jarcy Zee, Seung Seok Han, Sanjay Jain, Avi Z Rosenberg, Kuang Yu Jen, Pinaki Sarder, Kidney Precision Medicine Project, and Katherine R. Tuttle (Tuttle (Kidney Precision Medicine Project)

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Nephron overload as a therapeutic target to maximize kidney lifespan., Valerie A Luyckx, Andrew D Rule, Katherine Tuttle, Pierre Delanaye, Helen Liapis, Afschin Gandjour, Paola Romagnani, and Hans-Joachim Anders

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Accuracy and agreement of a large panel of endosonographers for endomicroscopy-guided virtual biopsy of pancreatic cystic lesions., Jorge D Machicado, Bertrand Napoleon, Anne Marie Lennon, Samer El-Dika, Stephen P Pereira, Damien Tan, Rahul Pannala, Mohit Girotra, Pradermchai Kongkam, Helga Bertani, Yunlu Feng, Hao Sijie, Ning Zhong, Vincent Valantin, Sarah Leblanc, Alice Hinton, and Somashekar G Krishna

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A scalable and modular automated pipeline for stitching of large electron microscopy datasets., Gayathri Mahalingam, Russel Torres, Daniel Kapner, Eric T Trautman, Tim Fliss, Shamishtaa Seshamani, Eric Perlman, Rob Young, Samuel Kinn, JoAnn Buchanan, Marc M Takeno, Wenjing Yin, Daniel J Bumbarger, Ryder P Gwinn, Julie Nyhus, Ed Lein, Steven J Smith, R Clay Reid, Khaled A Khairy, Stephan Saalfeld, Forrest Collman, and Nuno Macarico da Costa

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Disruption of cellular iron homeostasis by, Nunziata Maio, Russell P Saneto, Richard Steet, Márcio A Sotero de Menezes, Cindy Skinner, and Tracey A Rouault

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Water-Soluble Alternative to Simethicone to Safely Visualize GI-Tract. Have We Found Our White Whale?, Teri Mallard, Sandra Roswell, and Amarnath Ramakrishnan

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The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies., Jérémy Manry, Paul Bastard, Adrian Gervais, Tom Le Voyer, Jérémie Rosain, Quentin Philippot, Eleftherios Michailidis, Hans-Heinrich Hoffmann, Shohei Eto, Marina Garcia-Prat, Lucy Bizien, Alba Parra-Martínez, Rui Yang, Liis Haljasmägi, Mélanie Migaud, Karita Särekannu, Julia Maslovskaja, Nicolas de Prost, Yacine Tandjaoui-Lambiotte, Charles-Edouard Luyt, Blanca Amador-Borrero, Alexandre Gaudet, Julien Poissy, Pascal Morel, Pascale Richard, Fabrice Cognasse, Jesús Troya, Sophie Trouillet-Assant, Alexandre Belot, Kahina Saker, Pierre Garçon, Jacques G Rivière, Jean-Christophe Lagier, Stéphanie Gentile, Lindsey B Rosen, Elana Shaw, Tomohiro Morio, Junko Tanaka, David Dalmau, Pierre-Louis Tharaux, Damien Sene, Alain Stepanian, Bruno Mégarbane, Vasiliki Triantafyllia, Arnaud Fekkar, James R Heath, José Luis Franco, Juan-Manuel Anaya, Jordi Solé-Violán, Luisa Imberti, Andrea Biondi, Paolo Bonfanti, Riccardo Castagnoli, Ottavia M Delmonte, Yu Zhang, Andrew L Snow, Steven M Holland, Catherine M Biggs, Marcela Moncada-Vélez, Andrés Augusto Arias, Lazaro Lorenzo, Soraya Boucherit, Dany Anglicheau, Anna M Planas, Filomeen Haerynck, Sotirija Duvlis, Tayfun Ozcelik, Sevgi Keles, Ahmed A Bousfiha, Jalila El Bakkouri, Carolina Ramirez-Santana, Stéphane Paul, Qiang Pan-Hammarström, Lennart Hammarström, Annabelle Dupont, Alina Kurolap, Christine N Metz, Alessandro Aiuti, Giorgio Casari, Vito Lampasona, Fabio Ciceri, Lucila A Barreiros, Elena Dominguez-Garrido, Mateus Vidigal, Mayana Zatz, Diederik van de Beek, Sabina Sahanic, Ivan Tancevski, Yurii Stepanovskyy, Oksana Boyarchuk, Yoko Nukui, Miyuki Tsumura, Loreto Vidaur, Stuart G Tangye, Sonia Burrel, Darragh Duffy, Lluis Quintana-Murci, Adam Klocperk, Nelli Y Kann, Anna Shcherbina, Yu-Lung Lau, Daniel Leung, Matthieu Coulongeat, Julien Marlet, Rutger Koning, Luis Felipe Reyes, Angélique Chauvineau-Grenier, Fabienne Venet, Guillaume Monneret, Michel C Nussenzweig, Romain Arrestier, Idris Boudhabhay, Hagit Baris-Feldman, David Hagin, Joost Wauters, Isabelle Meyts, Adam H Dyer, Sean P Kennelly, Nollaig M Bourke, Rabih Halwani, Fatemeh Saheb Sharif-Askari, Karim Dorgham, Jérôme Sallette, Souad Mehlal Sedkaoui, Suzan AlKhater, Raúl Rigo-Bonnin, Francisco Morandeira, Lucie Roussel, Donald C Vinh, Christian Erikstrup, Antonio Condino-Neto, Carolina Prando, Anastasiia Bondarenko, András N Spaan, Laurent Gilardin, Jacques Fellay, Stanislas Lyonnet, Kaya Bilguvar, Richard P Lifton, Shrikant Mane, Mark S Anderson, Bertrand Boisson, Vivien Béziat, Shen-Ying Zhang, Evangelos Andreakos, Olivier Hermine, Aurora Pujol, Pärt Peterson, Trine H Mogensen, Lee Rowen, James Mond, Stéphanie Debette, Xavier de Lamballerie, Charles Burdet, Lila Bouadma, Marie Zins, Pere Soler-Palacin, Roger Colobran, Guy Gorochov, Xavier Solanich, Sophie Susen, Javier Martinez-Picado, Didier Raoult, Marc Vasse, Peter K Gregersen, Lorenzo Piemonti, Carlos Rodríguez-Gallego, Luigi D Notarangelo, Helen C Su, Kai Kisand, Satoshi Okada, Anne Puel, Emmanuelle Jouanguy, Charles M Rice, Pierre Tiberghien, Qian Zhang, Jean-Laurent Casanova, Laurent Abel, and Aurélie Cobat

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Physical and in silico immunopeptidomic profiling of a cancer antigen prostatic acid phosphatase reveals targets enabling TCR isolation., Zhiyuan Mao, Pavlo A Nesterenko, Jami McLaughlin, Weixian Deng, Giselle Burton Sojo, Donghui Cheng, Miyako Noguchi, William Chour, Diana C DeLucia, Kathryn A Finton, Yu Qin, Matthew B Obusan, Wendy Tran, Liang Wang, Nathanael J Bangayan, Lisa Ta, Chia-Chun Chen, Christopher S Seet, Gay M Crooks, John W Phillips, James R Heath, Roland K Strong, John K Lee, James A Wohlschlegel, and Owen N Witte

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Effect of MRI-Guided Fibrosis Ablation vs Conventional Catheter Ablation on Atrial Arrhythmia Recurrence in Patients With Persistent Atrial Fibrillation: The DECAAF II Randomized Clinical Trial., Nassir F Marrouche, Oussama Wazni, Christopher J McGann, Tom Greene, J Michael Dean, Lilas Dagher, Eugene Kholmovski, Moussa Mansour, Francis Marchlinski, David Wilber, Gerhard Hindricks, Christian Mahnkopf, Darryl Wells, Pierre Jais, Prashanthan Sanders, Johannes Brachmann, Jeroen J Bax, Leonie Morrison-de Boer, Thomas Deneke, Hugh Calkins, Christian Sohns, and Nazem Akoum

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CIO Podcast – Episode 25: Aaron Martin on Digital Health Innovation, Aaron Martin and John Lynn

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Engineered SH2 Domains for Targeted Phosphoproteomics., Gregory D Martyn, Gianluca Veggiani, Ulrike Kusebauch, Seamus R Morrone, Bradley P Yates, Alex U Singer, Jiefei Tong, Noah Manczyk, Gerald Gish, Zhi Sun, Igor Kurinov, Frank Sicheri, Michael F Moran, Robert L Moritz, and Sachdev S Sidhu

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More Thumbs Than Rules: Is Rationality an Exaptation?, Antonio Mastrogiorgio, Teppo Felin, Stuart Kauffman, and Mariano Mastrogiorgio

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ASO Visual Abstract: Timing of Presentation and Outcomes of Women with Stage IV Pregnancy-Associated Breast Cancer (PABC)., Regina Matar, Angelena Crown, Varadan Sevilimedu, Shari B Goldfarb, and Mary L Gemignani

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Phase 2 of extracellular RNA communication consortium charts next-generation approaches for extracellular RNA research., Bogdan Mateescu, Jennifer C Jones, Roger P Alexander, Eric Alsop, Ji Yeong An, Mohammad Asghari, Alex Boomgarden, Laura Bouchareychas, Alfonso Cayota, Hsueh-Chia Chang, Al Charest, Daniel T Chiu, Robert J Coffey, Saumya Das, Peter De Hoff, Andrew deMello, Crislyn D'Souza-Schorey, David Elashoff, Kiarash R Eliato, Jeffrey L Franklin, David J Galas, Mark B Gerstein, Ionita H Ghiran, David B Go, Stephen Gould, Tristan R Grogan, James N Higginbotham, Florian Hladik, Tony Jun Huang, Xiaoye Huo, Elizabeth Hutchins, Dennis K Jeppesen, Tijana Jovanovic-Talisman, Betty Y S Kim, Sung Kim, Kyoung-Mee Kim, Yong Kim, Robert R Kitchen, Vaughan Knouse, Emily L LaPlante, Carlito B Lebrilla, L James Lee, Kathleen M Lennon, Guoping Li, Feng Li, Tieyi Li, Tao Liu, Zirui Liu, Adam L Maddox, Kyle McCarthy, Bessie Meechoovet, Nalin Maniya, Yingchao Meng, Aleksandar Milosavljevic, Byoung-Hoon Min, Amber Morey, Martin Ng, John Nolan, Getulio P De Oliveira Junior, Michael E Paulaitis, Tuan Anh Phu, Robert L Raffai, Eduardo Reátegui, Matthew E Roth, David A Routenberg, Joel Rozowsky, Joseph Rufo, Satyajyoti Senapati, Sigal Shachar, Himani Sharma, Anil K Sood, Stavros Stavrakis, Alessandra Stürchler, Muneesh Tewari, Juan P Tosar, Alexander K Tucker-Schwartz, Andrey Turchinovich, Nedyalka Valkov, Kendall Van Keuren-Jensen, Kasey C Vickers, Lucia Vojtech, Wyatt N Vreeland, Ceming Wang, Kai Wang, ZeYu Wang, Joshua A Welsh, Kenneth W Witwer, David T W Wong, Jianping Xia, Ya-Hong Xie, Kaichun Yang, Mikołaj P Zaborowski, Chenguang Zhang, Qin Zhang, Angela M Zivkovic, and Louise C Laurent

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Picture of Staff from Endotronix, Nicole McConnell, James O Mudd, and Andrew Coletti

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Recurrence and Mortality Risk of Merkel Cell Carcinoma by Cancer Stage and Time From Diagnosis., Aubriana M McEvoy, Kristina Lachance, Daniel S Hippe, Kelsey Cahill, Yasman Moshiri, Christopher W Lewis, Neha Singh, Song Y Park, Zoe Thuesmunn, Maclean M Cook, Nora A Alexander, Lauren Zawacki, Hannah Thomas, Kelly G Paulson, and Paul Nghiem

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MRI-Guided Fibrosis Ablation vs Conventional Catheter Ablation for Patients With Persistent Atrial Fibrillation-Reply., Christopher McGann, Nazem Akoum, and Nassir Marrouche

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Effect of upadacitinib on reducing pain in patients with active psoriatic arthritis or ankylosing spondylitis: post hoc analysis of three randomised clinical trials., Iain B McInnes, Andrew J K Ostor, Philip Mease, William Tillett, Xenofon Baraliakos, Kurt de Vlam, Louis Bessette, Ralph Lippe, Anna Maniccia, Dai Feng, Tianming Gao, Patrick Zueger, Christopher Saffore, Koji Kato, In-Ho Song, and Atul Deodhar

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Screening for Adverse Childhood Experiences in Primary Care, Michelle McKay and Logan Shetlar

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Fireside Chat on the Asian American, Native Hawaiian, and Pacific Islander Special Edition of the, Monica McLemore, Zhuo Adam Chen, Elle Lett, Raynald Samoa, April Moreno, Bei Wu, Leena Yin, Donglan Stacy Zhang, Wanda Montalvo, and Celine Nguyen

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A glomerular transcriptomic landscape of apolipoprotein L1 in Black patients with focal segmental glomerulosclerosis., Michelle T McNulty, Damian Fermin, Felix Eichinger, Dongkeun Jang, Matthias Kretzler, Noël P Burtt, Martin R Pollak, Jason Flannick, Astrid Weins, David J Friedman, Nephrotic Syndrome Study Network (NEPTUNE), and Matthew G Sampson

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Suspecting and Diagnosing the Patient with Spondyloarthritis and What to Expect from Therapy., Philip Mease