Submissions from 2019
Monitoring therapeutic response and resistance: analysis of circulating tumor DNA in patients with ALK+ lung cancer., Leora Horn, Jennifer G Whisenant, Heather Wakelee, Karen L Reckamp, Huan Qiao, Ticiana A Leal, Liping Du, Jennifer Hernandez, Vincent Huang, George R Blumenschein, Saiama N Waqar, Sandip P Patel, Jorge Nieva, Geoffrey R Oxnard, Rachel E Sanborn, Tristan Shaffer, Kavita Garg, Allison Holzhausen, Kimberly Harrow, Chris Liang, Lee P Lim, Mark Li, and Christine M Lovly
Circulating tumor (ct) DNA analysis to monitor response and resistance to ensartinib in patients (pts) with ALK+ non-small cell lung cancer (NSCLC)., L Horn, J G Whisenant, H Wakelee, K L Reckamp, H Qiao, L Du, J Hernandez, V Huang, S N Waqar, S Patel, R E Sanborn, T Shaffer, K Garg, A Holzhausen, K Harrow, C Liang, L P Lim, M Li, and C M Lovly
Future Research Goals in Immunotherapy., Tyler W Hulett, Bernard A Fox, David J Messenheimer, Sebastian Marwitz, Tarsem Moudgil, Michael E Afentoulis, Keith W Wegman, Carmen Ballesteros-Merino, and Shawn M. Jensen
Safety and Efficacy of Durvalumab and Tremelimumab Alone or in Combination in Patients with Advanced Gastric and Gastroesophageal Junction Adenocarcinoma., Ronan J Kelly, Jeeyun Lee, Yung-Jue Bang, Khaldoun Almhanna, Mariela Blum Murphy, Daniel V T Catenacci, Hyun Cheol Chung, Zev A Wainberg, Michael K Gibson, Keun-Wook Lee, Johanna C Bendell, Crystal S Denlinger, Cheng Ean Chee, Takeshi Omori, Rom Leidner, Heinz-Josef Lenz, Yee Chao, Marlon C Rebelatto, Philip Brohawn, Peng He, Jennifer McDevitt, Siddharth Sheth, Judson M Englert, and Geoffrey Y Ku
Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal Cancer., Winifred Lo, Maria Parkhurst, Paul F Robbins, Eric Tran, Yong-Chen Lu, Li Jia, Jared J Gartner, Anna Pasetto, Drew Deniger, Parisa Malekzadeh, Thomas E Shelton, Todd Prickett, Satyajit Ray, Scott Kivitz, Biman C Paria, Isaac Kriley, David S Schrump, and Steven A Rosenberg
Addressing current challenges and future directions in immuno-oncology: expert perspectives from the 2017 NIBIT Foundation Think Tank, Siena, Italy., Michele Maio, George Coukos, Soldano Ferrone, Bernard A Fox, Wolf H Fridman, Patrick L Garcia, Michael Lahn, Olivier Provendier, Vincenzo Russo, Dominik Rüttinger, Aiman Shalabi, Zlatko Trajanoski, Jean Viallet, Jedd D Wolchok, and Ramy Ibrahim
Neoantigen screening identifies broad TP53 mutant immunogenicity in patients with epithelial cancers., Parisa Malekzadeh, Anna Pasetto, Paul F Robbins, Maria R Parkhurst, Biman C Paria, Li Jia, Jared J Gartner, Victoria Hill, Zhiya Yu, Nicholas P Restifo, Abraham Sachs, Eric Tran, Winifred Lo, Robert Pt Somerville, Steven A Rosenberg, and Drew C Deniger
Neoantigen screening identifies broad TP53 mutant immunogenicity in patients with epithelial cancers., Parisa Malekzadeh, Anna Pasetto, Paul F Robbins, Maria R Parkhurst, Biman C Paria, Li Jia, Jared J Gartner, Victoria Hill, Zhiya Yu, Nicholas P Restifo, Abraham Sachs, Eric Tran, Winifred Lo, Robert Pt Somerville, Steven A Rosenberg, and Drew C Deniger
Activating the Nucleic Acid-Sensing Machinery for Anticancer Immunity., Terry R Medler, Jaina M Patel, Alejandro Alice, Jason R Baird, Hong-Ming Hu, and Michael J Gough
Anti-PD-1 monoclonal antibody MEDI0680 in a phase I study of patients with advanced solid malignancies., Aung Naing, Jeffrey Infante, Sanjay Goel, Howard Burris, Chelsea Black, Shannon Marshall, Ikbel Achour, Susannah Barbee, Rena May, Chris Morehouse, Kristen Pollizzi, Xuyang Song, Keith Steele, Nairouz Elgeioushi, Farzana Walcott, Joyson Karakunnel, Patricia LoRusso, Amy Weise, Joseph Eder, Brendan Curti, and Michael Oberst
Use of "Research Techniques Made Simple" Series in Translational Topics Training in Dermatology at Oregon Health & Science University., Solveig Ophaug and Terry R Medler
A phase Ib study of pre-operative, locoregional IRX-2 cytokine immunotherapy to prime immune responses in patients with early stage breast cancer., David B Page, Joanna Pucilowska, Katherine G Sanchez, Alison K Conlin, Anupama Acheson, Kelly S Perlewitz, James H Imatani, Shagheyegh Aliabadi-Wahle, Nikki Moxon, Staci Mellinger, Amanda Y Seino, Maritza Martel, Yaping Wu, Zhaoyu Sun, William L. Redmond, Valerie Conrad, Venkatesh Rajamanickam, Dottie Waddell, Deborah Laxague, Monil Shah, Shu-Ching Chang, and Walter Urba
First-In-Human Study of Cemiplimab Alone or In Combination with Radiotherapy and/or Low Dose Cyclophosphamide in Patients with Advanced Malignancies., Kyriakos P Papadopoulos, Melissa L Johnson, Albert Craig Lockhart, Kathleen N Moore, Gerald S Falchook, Silvia C Formenti, Aung Naing, Richard D Carvajal, Lee S Rosen, Glen J Weiss, Rom Leidner, Jingjin Li, Anne Paccaly, Minjie Feng, Elizabeth Stankevich, Israel Lowy, Matthew G Fury, and Marka R Crittenden
Unique Neoantigens Arise from Somatic Mutations in Patients with Gastrointestinal Cancers., Maria R Parkhurst, Paul F Robbins, Eric Tran, Todd D Prickett, Jared J Gartner, Li Jia, Gabriel Ivey, Yong F Li, Mona El-Gamil, Almin Lalani, Jessica S Crystal, Abraham Sachs, Eric Groh, Satyajit Ray, Lien T Ngo, Scott Kivitz, Anna Pasetto, Rami Yossef, Frank J Lowery, Stephanie L Goff, Winifred Lo, Gal Cafri, Drew C Deniger, Parisa Malekzadeh, Mojgan Ahmadzadeh, John R Wunderlich, Robert P T Somerville, and Steven A Rosenberg
Peritumoral administration of DRibbles-pulsed antigen-presenting cells enhances the antitumor efficacy of anti-GITR and anti-PD-1 antibodies via an antigen presenting independent mechanism., Jaina M Patel, Zhihua Cui, Zhi-Fa Wen, Catherine T Dinh, and Hong-Ming Hu
Comprehensive Genomic Tumor Profiling, Brian D. Piening
Blockade of TGF-β signaling to enhance the antitumor response is accompanied by dysregulation of the functional activity of CD4, Magdalena J Polanczyk, Edwin Walker, Daniel Haley, Bella S Guerrouahen, and Emmanuel T Akporiaye
OX40 Agonist Tumor Immunotherapy Does Not Impact Regulatory T Cell Suppressive Function., Fanny Polesso, Minhaz Sarker, Andrew D Weinberg, Susan E Murray, and Amy E Moran
OX40 Agonist Tumor Immunotherapy Does Not Impact Regulatory T Cell Suppressive Function., Fanny Polesso, Minhaz Sarker, Andrew D Weinberg, Susan E Murray, and Amy E Moran
Immunological Complexity of the Prostate Cancer Microenvironment Influences the Response to Immunotherapy., Nataliya Prokhnevska, Dana A Emerson, Haydn T Kissick, and William L. Redmond
Non-TB Mycobacterial Infection-Bronchiectasis Nexus., Jerome M Reich
Non-TB Mycobacterial Infection-Bronchiectasis Nexus., Jerome M Reich
Two Radiographic Features Favoring Radiation Pneumonitis in the Differential Diagnosis., Jerome M Reich
Current Controversies in Cardiothoracic Imaging: Low-dose Computerized Tomographic Overdiagnosis of Lung Cancer is Substantial; Its Consequences are Underappreciated-Point., Jerome M Reich and Jong S Kim
Earlier Diagnosis Not Self-Evidently Beneficial: Natural History of Subcentimeter Lung Cancers., Jerome M Reich and Jong S Kim
Immunotherapy Toxicities., Katherine Sanchez, David B Page, and Walter Urba
High-Dose Ipilimumab and High-Dose Interleukin-2 for Patients With Advanced Melanoma., Ann W Silk, Howard L Kaufman, Brendan Curti, Janice M Mehnert, Kim Margolin, David McDermott, Joseph Clark, Jenna Newman, Praveen K Bommareddy, Lisa Denzin, Saltanat Najmi, Azra Haider, Weichung Shih, Michael P Kane, and Andrew Zloza
Immunotherapy for Head and Neck Cancer., Felix Sim, Rom Leidner, and Richard Bryan Bell
Immunotherapy for Head and Neck Cancer., Felix Sim, Rom Leidner, and Richard Bryan Bell
Immunotherapy for Head and Neck Cancer., Felix Sim, Rom Leidner, and Richard Bryan Bell
Major pathologic response on biopsy (MPRbx) in patients with advanced melanoma treated with anti-PD-1: evidence for an early, on-therapy biomarker of response., J E Stein, A Soni, L Danilova, T R Cottrell, T F Gajewski, F S Hodi, S Bhatia, W J Urba, W H Sharfman, M Wind-Rotolo, R Edwards, E J Lipson, and J M Taube
Subcellular compartmentalization of PKM2 identifies anti-PKM2 therapy response in vitro and in vivo mouse model of human non-small-cell lung cancer., Akiko Suzuki, Sachin Puri, Pamela Leland, Ankit Puri, Tarsem Moudgil, Bernard A Fox, Raj K Puri, and Bharat H Joshi
Prevalence of trismus in patients with head and neck cancer: A systematic review with meta-analysis., Amber L Watters, Shane Cope, Meir N Keller, Mariela Padilla, and Reyes Enciso
Multispectral Fluorescence Imaging Allows for Distinctive Topographic Assessment and Subclassification of Tumor-Infiltrating and Surrounding Immune Cells., Claudia Wickenhauser, Daniel Bethmann, Zipei Feng, Shawn M. Jensen, Carmen Ballesteros-Merino, Chiara Massa, Andre Steven, Marcus Bauer, Peter Kaatzsch, Nikolaos Pazaitis, Georgiana Toma, Carlo Bifulco, Bernard A Fox, and Barbara Seliger
A microbial-based cancer vaccine for induction of EGFRvIII-specific CD8+ T cells and anti-tumor immunity., Lauren Zebertavage, Shelly Bambina, Jessica Shugart, Alejandro Alice, Kyra D Zens, Peter Lauer, Bill Hanson, Michael J. Gough, Marka R Crittenden, and Keith S Bahjat
Longitudinal multi-omics of host-microbe dynamics in prediabetes., Wenyu Zhou, M Reza Sailani, Kévin Contrepois, Yanjiao Zhou, Sara Ahadi, Shana R Leopold, Martin J Zhang, Varsha Rao, Monika Avina, Tejaswini Mishra, Jethro Johnson, Brittany Lee-McMullen, Songjie Chen, Ahmed A Metwally, Thi Dong Binh Tran, Hoan Nguyen, Xin Zhou, Brandon Albright, Bo-Young Hong, Lauren Petersen, Eddy Bautista, Blake Hanson, Lei Chen, Daniel Spakowicz, Amir Bahmani, Denis Salins, Benjamin Leopold, Melanie Ashland, Orit Dagan-Rosenfeld, Shannon Rego, Patricia Limcaoco, Elizabeth Colbert, Candice Allister, Dalia Perelman, Colleen Craig, Eric Wei, Hassan Chaib, Daniel Hornburg, Jessilyn Dunn, Liang Liang, Sophia Miryam Schüssler-Fiorenza Rose, Kim Kukurba, Brian D. Piening, Hannes Rost, David Tse, Tracey McLaughlin, Erica Sodergren, George M Weinstock, and Michael Snyder
Submissions from 2018
Clinical Development of Novel Drug-Radiotherapy Combinations., Saif S Ahmad, Marka R Crittenden, Phuoc T Tran, Paul G Kluetz, Gideon M Blumenthal, Helen Bulbeck, Richard D Baird, Kaye J Williams, Tim Illidge, Stephen M Hahn, Theodore S Lawrence, Patricia A Spears, Amanda J Walker, and Ricky A Sharma
Amplifying IFN-γ Signaling in Dendritic Cells by CD11c-Specific Loss of SOCS1 Increases Innate Immunity to Infection while Decreasing Adaptive Immunity., Alejandro F Alice, Gwen Kramer, Shelly Bambina, Jason R Baird, Keith S Bahjat, Michael J Gough, and Marka R Crittenden
Perspectives in immunotherapy: meeting report from the Immunotherapy Bridge (29-30 November, 2017, Naples, Italy)., Paolo A Ascierto, James Brugarolas, Luigi Buonaguro, Lisa H Butterfield, David Carbone, Bruno Daniele, Robert Ferris, Bernard A Fox, Jérôme Galon, Cesare Gridelli, Howard L Kaufman, Christopher A Klebanoff, Ignacio Melero, Paul Nathan, Chrystal M Paulos, Marco Ruella, Ryan Sullivan, Hassane Zarour, and Igor Puzanov
Perspectives in melanoma: Meeting report from the Melanoma Bridge (30 November-2 December, 2017, Naples, Italy)., Paolo A Ascierto, Igor Puzanov, Sanjiv S Agarwala, Carlo Bifulco, Gerardo Botti, Corrado Caracò, Gennaro Ciliberto, Michael A Davies, Reinhard Dummer, Soldano Ferrone, Thomas F Gajewski, Claus Garbe, Jason J Luke, Francesco M Marincola, Giuseppe Masucci, Janice M Mehnert, Nicola Mozzillo, Giuseppe Palmieri, Michael A Postow, Stephen P Schoenberger, Ena Wang, and Magdalena Thurin
MV-626, a potent and selective inhibitor of ENPP1 enhances STING activation and augments T-cell mediated anti-tumor activity in vivo, Jason Baird, Gregory Dietsch, Vincent Florio, Michael Gallatin, Clayton Knox, Joshua Odingo, Marka Crittenden, and Michael J. Gough
Evaluation of explant responses to STING ligands: personalized immunosurgical therapy for head and neck squamous cell carcinoma., Jason R Baird, R Bryan Bell, Victoria Troesch, David J Friedman, Shelly Bambina, Gwen Kramer, Tiffany Blair, Terry R Medler, Yaping Wu, Zhaoyu Sun, Tanja D de Gruijl, Rieneke van de Ven, Rom Leidner, Marka R Crittenden, and Michael J. Gough
Integrative spatially-resolved, high-plex digital profiling enables characterization of complex immune biology in the tumor microenvironment of mesothelioma, Carmen Ballesteros-Merino, Moritz Widmaier, Sarah Church, Thomas Herz, Alexei Budco, Das Medrikova, Ivan Kanchev, Andrew White, Douglas Hinerfeld, Shawn Jensen, John Handy, Rachel Sanborn, Carlo Bifulco, Sarah Warren, Joseph Beechem, and Bernard .. Fox
SITC 2018 workshop report: Immuno-Oncology Biomarkers: State of the Art., Lisa H Butterfield, Mary L Disis, Bernard A Fox, David R Kaufman, Samir N Khleif, and Ena Wang
A Phase II Study of Celecoxib With Irinotecan, 5-Fluorouracil, and Leucovorin in Patients With Previously Untreated Advanced or Metastatic Colorectal Cancer., Emerson Y Chen, Charles D Blanke, Daniel G Haller, Al B Benson, Tomislav Dragovich, Heinz-Josef Lenz, Carlos Robles, Hong Li, Motomi Mori, Nora Mattek, Rachel E Sanborn, and Charles D Lopez
Blocking immunoinhibitory receptor LILRB2 reprograms tumor-associated myeloid cells and promotes antitumor immunity., Hui-Ming Chen, William van der Touw, Yuan Shuo Wang, Kyeongah Kang, Sunny Mai, Jilu Zhang, Dayanira Alsina-Beauchamp, James A Duty, Sathish Kumar Mungamuri, Bin Zhang, Thomas Moran, Richard Flavell, Stuart Aaronson, Hong-Ming Hu, Hisashi Arase, Suresh Ramanathan, Raja Flores, Ping-Ying Pan, and Shu-Hsia Chen
Phase IIIb safety results from an expanded-access protocol of talimogene laherparepvec for patients with unresected, stage IIIB-IVM1c melanoma., Jason Chesney, Sanjay Awasthi, Brendan Curti, Laura Hutchins, Gerald Linette, Pierre Triozzi, Marcus C B Tan, Russell E Brown, John Nemunaitis, Eric Whitman, Christopher Windham, Jose Lutzky, Gerald F Downey, Nicolas Batty, and Thomas Amatruda
A multi-center phase II study of high dose interleukin-2 sequenced with vemurafenib in patients with BRAF-V600 mutation positive metastatic melanoma., Joseph I Clark, Jatinder Singh, Marc S Ernstoff, Christopher D Lao, Lawrence E Flaherty, Theodore F Logan, Brendan Curti, Sanjiv S Agarwala, Bret Taback, Lee Cranmer, Jose Lutzky, Theresa L Luna, Sandra Aung, and David H Lawson
Implementation and Validation of an Automated Flow Cytometry Analysis Pipeline for Human Immune Profiling., Valerie Conrad, Christopher Dubay, Mehrnoush Malek, Ryan R Brinkman, Yoshinobu Koguchi, and William L. Redmond
Delayed immune-related events after discontinuation of immunotherapy – DIRE syndrome?, Marcus Couey, R. Bryan Bell, Ashish Patel, Marka R Crittenden, Brendan Curti, and Rom Leidner
Tumor cure by radiation therapy and checkpoint inhibitors depends on pre-existing immunity., Marka R Crittenden, Lauren Zebertavage, Gwen Kramer, Shelly Bambina, David Friedman, Victoria Troesch, Tiffany Blair, Jason R Baird, Alejandro F Alice, and Michael J Gough
Immunotherapy in Advanced Renal Cancer - Is Cure Possible?, Brendan D Curti
Polyethyleneimine modification of aluminum hydroxide nanoparticle enhances antigen transportation and cross-presentation of dendritic cells., Heng Dong, Zhi-Fa Wen, Lin Chen, Na Zhou, Hui Liu, Shiling Dong, Hong-Ming Hu, and Yongbin Mou
Co-expression of CD39 and CD103 identifies tumor-reactive CD8 T cells in human solid tumors., Thomas Duhen, Rebekka Duhen, Ryan Montler, Jake Moses, Tarsem Moudgil, Noel F de Miranda, Cheri P Goodall, Tiffany C Blair, Bernard A Fox, Jason E McDermott, Shu-Ching Chang, Gary Grunkemeier, Rom Leidner, Richard Bryan Bell, and Andrew D Weinberg
Earle A. Chiles Research Institute 2017 Year In Review, Earle A. Chiles Research Institute
Overcoming Tumor-Induced Immune Suppression: From Relieving Inhibition to Providing Costimulation with T Cell Agonists., Dana A Emerson and William L Redmond
The role of Galectin-3 in modulating tumor growth and immunosuppression within the tumor microenvironment., Mohammad Farhad, Annah S Rolig, and William L Redmond
Tumor cell-released autophagosomes (TRAP) enhance apoptosis and immunosuppressive functions of neutrophils., Rong Gao, Jie Ma, Zhifa Wen, Peiying Yang, Jinjin Zhao, Meng Xue, Yongqiang Chen, Mohanad Aldarouish, Hong-Ming Hu, Xue-Jun Zhu, Ning Pan, and Li-Xin Wang
Randomized phase III study of docetaxel plus bavituximab in previously treated advanced non-squamous non-small-cell lung cancer., D E Gerber, L Horn, M Boyer, Rachel E Sanborn, R Natale, R Palmero, P Bidoli, I Bondarenko, P Germonpre, D Ghizdavescu, A Kotsakis, H Lena, G Losonczy, K Park, W-C Su, M Tang, J Lai, N L Kallinteris, J S Shan, M Reck, and D R Spigel
A Placebo-Controlled Phase II Study of Ruxolitinib in Combination With Pemetrexed and Cisplatin for First-Line Treatment of Patients With Advanced Nonsquamous Non-Small-Cell Lung Cancer and Systemic Inflammation., Giuseppe Giaccone, Rachel E Sanborn, Saiama N Waqar, Alex Martinez-Marti, Santiago Ponce, Huiling Zhen, Gerard Kennealey, Susan Erickson-Viitanen, and Eric Schaefer
Inducible T cell Co-stimulator (ICOS) is upregulated on lymphocytes following radiation of tumors and ICOS agonism in combination with radiation results in enhanced tumor control, Michael J. Gough, Shelly Bambina, Monica Gostissa, Christopher Harvey, David Friedman, and Marka R Crittenden
Aberrant Lck Signal via CD28 Costimulation Augments Antigen-Specific Functionality and Tumor Control by Redirected T Cells with PD-1 Blockade in Humanized Mice., Pratiksha Gulati, Julia Rühl, Abhilash Kannan, Magdalena Pircher, Petra Schuberth, Katarzyna J Nytko, Martin Pruschy, Simon Sulser, Mark Haefner, Shawn Jensen, Alex Soltermann, Wolfgang Jungraithmayr, Maya Eisenring, Thomas Winder, Panagiotis Samaras, Annett Tabor, Rene Stenger, Roger Stupp, Walter Weder, Christoph Renner, Christian Münz, and Ulf Petrausch
Exploring optimal sequencing of radiation and immunotherapy combinations., Andrew J Gunderson and Kristina H Young
Where's the Money? Revenues associated with 3000 Lung Cancer Screens, John Handy Jr., Courtney Wood, Erika Rauch, Kevin Olson, Roshanthi Weerasinghe, Rachel Sanborn, and Micheal Skokan
Ensartinib (X-396) in ALK-Positive Non-Small Cell Lung Cancer: Results from a First-in-Human Phase I/II, Multicenter Study., Leora Horn, Jeffrey R Infante, Karen L Reckamp, George R Blumenschein, Ticiana A Leal, Saiama N Waqar, Barbara J Gitlitz, Rachel E Sanborn, Jennifer G Whisenant, Liping Du, Joel W Neal, Jon P Gockerman, Gary Dukart, Kimberly Harrow, Chris Liang, James J Gibbons, Allison Holzhausen, Christine M Lovly, and Heather A Wakelee
Single cell sequencing to identify TCRs that recognize autologous tumor cells after vaccination with allogeinic DRibble vaccine, Hong-Ming Hu, Christopher C. Paustian, Zhifa Wen, Tarsem L. Moudgil, Traci L. Hilton, Sam Bookhardt, Guangjie Yu, Eric Tran, Venkatesh Rajamanickam, Walter Urba, Rachel E. Sanborn, and Bernard A. Fox
Coordinated responses to individual tumor antigens by IgG antibody and CD8+ T cells following cancer vaccination., Tyler W Hulett, Shawn M. Jensen, Phillip A Wilmarth, Ashok P Reddy, Carmen Ballesteros-Merino, Michael E Afentoulis, Christopher Dubay, Larry L David, and Bernard A Fox
Pegzilarginase in combination with agonist anti-OX40 therapy enhances T cell priming and effector function leading to improved tumor regression and survival, Melissa Kasiewicz, Annah Rolig, Elizabeth Sturgill, Mark Badeaux, Scott Rowlinson, and William L. Redmond
Functional Anatomic Computer Engineered Surgery Protocol for the Management of Self-Inflicted Gunshot Wounds to the Maxillofacial Skeleton., Baber Khatib, Karl Cuddy, Allen Cheng, Ashish Patel, Felix Sim, Melissa Amundson, Savannah Gelesko, Tuan Bui, Eric J Dierks, and Richard Bryan Bell
The Biaxial Double-Barrel Fibula Flap-A Simplified Technique for Fibula Maxillary Reconstruction., Baber Khatib, Ashish Patel, Eric J Dierks, R Bryan Bell, and Allen Cheng
Novel frontiers in detecting cancer metastasis., Stanley P Leong, Carmen Ballesteros-Merino, Shawn M Jensen, Sebastian Marwitz, Carlo Bifulco, Bernard A Fox, and Mojca Skoberne
SPIO Enhance the Cross-Presentation and Migration of DCs and Anionic SPIO Influence the Nanoadjuvant Effects Related to Interleukin-1β., Hui Liu, Heng Dong, Na Zhou, Shiling Dong, Lin Chen, Yanxiang Zhu, Hong-Ming Hu, and Yongbin Mou
Open-source digital image analysis of whole-slide multiplex immunohistochemistry, Nikhil Lonberg, Carmen Ballesteros-Merino, Shawn Jensen, and Bernard A Fox
PD-L1 expression with immune-infiltrate evaluation and outcome prediction in melanoma patients treated with ipilimumab., Gabriele Madonna, Carmen Ballesteros-Merino, Zipei Feng, Carlo Bifulco, Mariaelena Capone, Diana Giannarelli, Domenico Mallardo, Ester Simeone, Antonio M Grimaldi, Corrado Caracò, Gerardo Botti, Bernard A Fox, and Paolo A Ascierto
Starting the Fight in the Tumor: Expert Recommendations for the Development of Human Intratumoral Immunotherapy (HIT-IT)., A Marabelle, R Andtbacka, K Harrington, I Melero, R Leidner, T de Baere, C Robert, P A Ascierto, J-F Baurain, M Imperiale, S Rahimian, D Tersago, E Klumper, M Hendriks, R Kumar, M Stern, K Öhrling, C Massacesi, I Tchakov, A Tse, J-Y Douillard, J Tabernero, J Haanen, and J Brody
Preliminary evaluation of a novel whole slide multispectral assessment of seven markers: Potential to minimize bias in the characterization of the tumor immune environment, Carmen Ballesteros Merino, Shawn Jensen, Carla Coltharp, Kristin Roman, Chichung Wang, Nikhil Lonberg, Sebastian Marwitz, Tarsem Moudgil, William Miller, William Redmond, Yoshinobu Koguchi, Carlo Bifulco, Clifford Hoyt, and Bernard A. Fox
Potent Immune Modulation by MEDI6383, an Engineered Human OX40 Ligand IgG4P Fc Fusion Protein., Michael D Oberst, Catherine Augé, Chad Morris, Stacy Kentner, Kathy Mulgrew, Kelly McGlinchey, James Hair, Shino Hanabuchi, Qun Du, Melissa Damschroder, Hui Feng, Steven Eck, Nicholas Buss, Lolke de Haan, Andrew J Pierce, Haesun Park, Andrew Sylwester, Michael K Axthelm, Louis Picker, Nicholas P Morris, Andrew D Weinberg, and Scott A Hammond
Monosomy 17 in potentially curable HER2-amplified breast cancer: prognostic and predictive impact., David B Page, Hannah Wen, Edi Brogi, Dana Dure, Dara Ross, Kateri J Spinelli, Sujata Patil, Larry Norton, Clifford Hudis, and Heather L McArthur
Updated efficacy of first or second-line pembrolizumab plus in metastatic triple negative breast cancer and correlations with baseline lymphocyte and naïve CD4+ T-cell count, David Page, Joanna Pucilowska, Laura Bennetts, I Kim, Katherine Sanchez, Maritza Martel, Alison Conlin, Nikki Moxon, Staci Mellinger, Anupama Acheson, K Kemmer, Z Mitri, J Vuky, J Ahn, C Abaya, T Manigault, R Basho, Walter Urba, and HL McArthur
International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study., Franck Pagès, Bernhard Mlecnik, Florence Marliot, Gabriela Bindea, Fang-Shu Ou, Carlo Bifulco, Alessandro Lugli, Inti Zlobec, Tilman T Rau, Martin D Berger, Iris D Nagtegaal, Elisa Vink-Börger, Arndt Hartmann, Carol Geppert, Julie Kolwelter, Susanne Merkel, Robert Grützmann, Marc Van den Eynde, Anne Jouret-Mourin, Alex Kartheuser, Daniel Léonard, Christophe Remue, Julia Y Wang, Prashant Bavi, Michael H A Roehrl, Pamela S Ohashi, Linh T Nguyen, SeongJun Han, Heather L MacGregor, Sara Hafezi-Bakhtiari, Bradly G Wouters, Giuseppe V Masucci, Emilia K Andersson, Eva Zavadova, Michal Vocka, Jan Spacek, Lubos Petruzelka, Bohuslav Konopasek, Pavel Dundr, Helena Skalova, Kristyna Nemejcova, Gerardo Botti, Fabiana Tatangelo, Paolo Delrio, Gennaro Ciliberto, Michele Maio, Luigi Laghi, Fabio Grizzi, Tessa Fredriksen, Bénédicte Buttard, Mihaela Angelova, Angela Vasaturo, Pauline Maby, Sarah E Church, Helen K Angell, Lucie Lafontaine, Daniela Bruni, Carine El Sissy, Nacilla Haicheur, Amos Kirilovsky, Anne Berger, Christine Lagorce, Jeffrey P Meyers, Christopher Paustian, Zipei Feng, Carmen Ballesteros-Merino, Jeroen Dijkstra, Carlijn van de Water, Shannon van Lent-van Vliet, Nikki Knijn, Ana-Maria Mușină, Dragos-Viorel Scripcariu, Boryana Popivanova, Mingli Xu, Tomonobu Fujita, Shoichi Hazama, Nobuaki Suzuki, Hiroaki Nagano, Kiyotaka Okuno, Toshihiko Torigoe, Noriyuki Sato, Tomohisa Furuhata, Ichiro Takemasa, Kyogo Itoh, Prabhu S Patel, Hemangini H Vora, Birva Shah, Jayendrakumar B Patel, Kruti N Rajvik, Shashank J Pandya, Shilin N Shukla, Yili Wang, Guanjun Zhang, Yutaka Kawakami, Francesco M Marincola, Paolo A Ascierto, Daniel J Sargent, Bernard A Fox, and Jérôme Galon
Efficacy and toxicity of therapy immediately after treatment with nivolumab in relapsed multiple myeloma., Matthew J Pianko, Samuel A Funt, David B Page, Deepika Cattry, Emma C Scott, Stephen M Ansell, Ivan M Borrello, Martin Gutierrez, Nikoletta Lendvai, Hani Hassoun, C Ola Landgren, and Alexander M Lesokhin
New Clues to Human Longevity, Brian D. Piening
Impact of Specimen Heterogeneity on Biomarkers in Repository Samples from Patients with Acute Myeloid Leukemia: A SWOG Report., Era L Pogosova-Agadjanyan, Anna Moseley, Megan Othus, Frederick R Appelbaum, Thomas R Chauncey, I-Ming L Chen, Harry P Erba, John E Godwin, Min Fang, Kenneth J Kopecky, Alan F List, Galina L Pogosov, Jerald P Radich, Cheryl L Willman, Brent L Wood, Soheil Meshinchi, and Derek L Stirewalt
Late stage tumor regression after PD-L1 blockade with a concurrent OX40 agonist., Fanny Polesso, Andrew D Weinberg, and Amy E Moran
Tumor infiltrating lymphocyte recruitment after peri-lymphatic IRX-2 cytokine immunotherapy in resectable breast cancer and head and neck carcinoma, Joanna Pucilowska, Venkatesh Rajamanickam, Nikki Moxon, Monil Shah, Maritza Martel, Alison Conlin, James E. Egan, and David B. Page
Perilymphatic IRX-2 cytokine therapy to enhance tumor infiltrating lymphocytes and PD-L1 expression preceding curative-intent therapy in early stage breast cancer, Joanna Pucilowska, Venkatesh Rajamanickam, Katherine Sanchez, Valerie Conrad, Alison Conlin, Shagheyegh Aliabadi-Wahle, Shu-Ching Chang, Gary Grunkemeier, Nikki Moxon, Staci Mellinger, Maritza Martel, James Egan, Monil Shah, and David B Page
Chirping Rales in Hypersensitivity Pneumonitis., Jerome M Reich
In Defense of Lady Windermere Syndrome., Jerome M Reich
Reservations Regarding Lung Cancer Screening Guidelines., Jerome M Reich
Sarcoidosis in WTC-Exposed workers., Jerome M Reich
The Curious Omission of Treatment as a Predictor of Pulmonary Sarcoidosis Mortality., Jerome M Reich
Diminished Susceptibility of African-Americans to Non-tuberculous Mycobacterial Disease., Jerome M Reich and Jong S Kim
Erratum to inequivalence of non-aggressiveness in clinically diagnosed lung cancers and overdiagnosis in lung cancer screening trials., Jerome M Reich and Jong S Kim
NKTR-214 (CD122-biased agonist) and NKTR-262 (TLR7/8 agonist) combination treatment pairs local innate immune activation with systemic CD8+ T cell expansion to enhance anti-tumor immunity, Annah S. Rolig, Daniel Rose, Saul Kivimäe, Deborah Charych, Werner Rubas, Jonathan Zalevsky, and William L. Redmond
MHC class I loaded ligands from breast cancer cell lines: A potential HLA-I-typed antigen collection., Dmitri V Rozanov, Nikita D Rozanov, Kami E Chiotti, Ashok Reddy, Phillip A Wilmarth, Larry L David, Seung W Cha, Sunghee Woo, Pavel Pevzner, Vineet Bafna, Gregory G Burrows, Juha K Rantala, Trevor Levin, Pavana Anur, Katie Johnson-Camacho, Shaadi Tabatabaei, Daniel J Munson, Tullia C Bruno, Jill E Slansky, John W Kappler, Naoto Hirano, Sebastian Boegel, Bernard A Fox, Colt Egelston, Diana L Simons, Grecia Jimenez, Peter P Lee, Joe W Gray, and Paul T Spellman
The Epigenomic Landscape of Pituitary Adenomas Reveals Specific Alterations and Differentiates Among Acromegaly, Cushing's Disease and Endocrine-Inactive Subtypes., Matthew P Salomon, Xiaowen Wang, Diego M Marzese, Sandy C Hsu, Nellie Nelson, Xin Zhang, Chikako Matsuba, Yuki Takasumi, Carmen Ballesteros-Merino, Bernard A Fox, Garni Barkhoudarian, Daniel F Kelly, and Dave S B Hoon
Preliminary results from a first-in-human phase 1 study of the CD40 agonist monoclonal antibody (mAb) CDX-1140, Rachel Sanborn, Michael S. Gordon, Mark O'Hara, Nina Bhardwaj, Yi He, Tracey Rawls, Tibor Keler, and Michael Yellin
Immunotherapy in metastatic urothelial carcinoma: focus on immune checkpoint inhibition., Arlene Siefker-Radtke and Brendan Curti
Combined anti-PD-1 and anti-LAG-3 checkpoint blockade enhances CD8+ TIL effector function while reducing Tregs leading to reduced immune suppression and improved overall survival, Elizabeth Sturgill, Courtney Mick, David Jenkins, Johanna Kaufmann, and William L. Redmond
An update on the Society for Immunotherapy of Cancer consensus statement on tumor immunotherapy for the treatment of cutaneous melanoma: version 2.0., Ryan J Sullivan, Michael B Atkins, John M Kirkwood, Sanjiv S Agarwala, Joseph I Clark, Marc S Ernstoff, Leslie Fecher, Thomas F Gajewski, Brian Gastman, David H Lawson, Jose Lutzky, David F McDermott, Kim A Margolin, Janice M Mehnert, Anna C Pavlick, Jon M Richards, Krista M Rubin, William Sharfman, Steven Silverstein, Craig L Slingluff, Vernon K Sondak, Ahmad A Tarhini, John A Thompson, Walter J Urba, Richard L White, Eric D Whitman, F Stephen Hodi, and Howard L Kaufman
