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Submissions from 2022

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Vessel Wall Enhancement in Unilateral Primary Angiitis of the Central Nervous System., Adrian Budhram, Shailee S Shah, Christopher P Wood, Michael A Lane, Kyle E Smoot, and Brian G Weinshenker

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Cell-free plasma microRNAs that identify patients with glioblastoma., Matias A Bustos, Negin Rahimzadeh, Suyeon Ryu, Rebecca Gross, Linh T Tran, Victor M Renteria-Lopez, Romela Irene Ramos, Amy Eisenberg, Parvinder Hothi, Santosh Kesari, Garni Barkhoudarian, Yuki Takasumi, Charles Cobbs, Daniel F Kelly, and Dave Hoon

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Safety of Fingolimod in Patients with Multiple Sclerosis Switched from Natalizumab: Results from TRANSITION-A 2-Year, Multicenter, Observational, Cohort Study., Helmut Butzkueven, Paul S Giacomini, Stanley Cohan, Tjalf Ziemssen, Daniel Sienkiewicz, Ying Zhang, Yvonne Geissbühler, Diego Silva, Davorka Tomic, Harald Kropshofer, and Maria Trojano

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Local connectivity and synaptic dynamics in mouse and human neocortex., Luke Campagnola, Stephanie C Seeman, Thomas Chartrand, Lisa Kim, Alex Hoggarth, Clare Gamlin, Shinya Ito, Jessica Trinh, Pasha Davoudian, Cristina Radaelli, Mean-Hwan Kim, Travis Hage, Thomas Braun, Lauren Alfiler, Julia Andrade, Phillip Bohn, Rachel Dalley, Alex Henry, Sara Kebede, Mukora Alice, David Sandman, Grace Williams, Rachael Larsen, Corinne Teeter, Tanya L Daigle, Kyla Berry, Nadia Dotson, Rachel Enstrom, Melissa Gorham, Madie Hupp, Samuel Dingman Lee, Kiet Ngo, Philip R Nicovich, Lydia Potekhina, Shea Ransford, Amanda Gary, Jeff Goldy, Delissa McMillen, Trangthanh Pham, Michael Tieu, La'Akea Siverts, Miranda Walker, Colin Farrell, Martin Schroedter, Cliff Slaughterbeck, Charles Cobb, Richard Ellenbogen, Ryder P Gwinn, C Dirk Keene, Andrew L Ko, Jeffrey G Ojemann, Daniel L Silbergeld, Daniel Carey, Tamara Casper, Kirsten Crichton, Michael Clark, Nick Dee, Lauren Ellingwood, Jessica Gloe, Matthew Kroll, Josef Sulc, Herman Tung, Katherine Wadhwani, Krissy Brouner, Tom Egdorf, Michelle Maxwell, Medea McGraw, Christina Alice Pom, Augustin Ruiz, Jasmine Bomben, David Feng, Nika Hejazinia, Shu Shi, Aaron Szafer, Wayne Wakeman, John Phillips, Amy Bernard, Luke Esposito, Florence D D'Orazi, Susan Sunkin, Kimberly Smith, Bosiljka Tasic, Anton Arkhipov, Staci Sorensen, Ed Lein, Christof Koch, Gabe Murphy, Hongkui Zeng, and Tim Jarsky

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QLTI-22. IMPROVING BRAIN CANCER PATIENT ACCESS TO CLINICAL TRIALS ACROSS SEVEN COMMUNITY HOSPITALS, THE PROVIDENCE SOUTHERN CALIFORNIA CLINICAL RESEARCH NETWORK, Jose Carrillo, Naveed Wagle, Akanksha Sharma, Tiffany Juarez, Minhdan Nguyen, Judy D Truong, Timothy E. Byun, Brad Bott, Nanor Bozoyan, David J Park, and Santosh Kesari

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Deep Brain Stimulation Surgery Using a Mobile Intraoperative CT Scanner., Daniel Cavalcante, Muhammad S Ghauri, and Ryder P Gwinn

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Smart Consumer Wearables as Digital Diagnostic Tools: A Review., Shweta Chakrabarti, Nupur Biswas, Lawrence D Jones, Santosh Kesari, and Shashaanka Ashili

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Encephaloduroarteriosynangiosis Operative Technique and Intraoperative Anesthesia Management: Treatment From Both Sides of the Curtain., Julie L Chan, Miguel D Quintero-Consuegra, Robin M Babadjouni, Daniel Chang, Zachary R Barnard, Neil A Martin, Keren Ziv, Barbara M Van de Wiele, and Nestor R Gonzalez

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Into the Spine Metaverse: Reflections on a future, Jens R Chapman, Jeffrey C Wang, and Karsten Wiechert

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Physician satisfaction with telemedicine and in-person visits in otolaryngology., Janet S Choi, Matthew Lin, Soyun Park, Faiz Abdur-Rahman, James H Kim, and Courtney C J Voelker

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NCMP-07. CASE SERIES OF REGULARLY SCHEDULED MANNITOL INFUSIONS SHOWING WITH PROLONGED CLINICAL BENEFIT FOR MANAGEMENT OF CEREBRAL EDEMA IN GLIOMAS, Jared Chow, Jose Carrillo, Santosh Kesari, Akanksha Sharma, Minhdan Nguyen, Judy D Truong, and Naveed Wagle

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The Two Sides of Siponimod: Evidence for Brain and Immune Mechanisms in Multiple Sclerosis., Stanley Cohan, Ralph H B Benedict, Bruce A C Cree, John DeLuca, Le H Hua, and Jerold Chun

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Magnetic resonance imaging-guided focused ultrasound thalamotomy for essential tremor: 5-year follow-up results., G Rees Cosgrove, Nir Lipsman, Andres M Lozano, Jin Woo Chang, Casey Halpern, Pejman Ghanouni, Howard Eisenberg, Paul Fishman, Takaomi Taira, Michael L Schwartz, Nathan McDannold, Michael Hayes, Susie Ro, Binit Shah, Ryder Gwinn, Veronica E Santini, Kullervo Hynynen, and W Jeff Elias

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Head-Mounted Augmented Reality in the Planning of Cerebrovascular Neurosurgical Procedures: A Single-Center Initial Experience., Matias Costa, Clifford Pierre, Juan Vivanco-Suarez, Matias Baldoncini, Zane Tymchak, Akshal Patel, and Stephen J Monteith

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Easing the Journey-an Updated Review of Palliative Care for the Patient with High-Grade Glioma., Rita C Crooms, Margaret O Johnson, Heather Leeper, Ambereen Mehta, Michelle McWhirter, and Akanksha Sharma

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PARK7/DJ-1 promotes pyruvate dehydrogenase activity and maintains T, Egle Danileviciute, Ni Zeng, Christophe M Capelle, Nicole Paczia, Mark A Gillespie, Henry Kurniawan, Mohaned Benzarti, Myriam P Merz, Djalil Coowar, Sabrina Fritah, Daniela Maria Vogt Weisenhorn, Gemma Gomez Giro, Melanie Grusdat, Alexandre Baron, Coralie Guerin, Davide G Franchina, Cathy Léonard, Olivia Domingues, Sylvie Delhalle, Wolfgang Wurst, Jonathan D Turner, Jens Christian Schwamborn, Johannes Meiser, Rejko Krüger, Jeff Ranish, Dirk Brenner, Carole L Linster, Rudi Balling, Markus Ollert, and Feng Q Hefeng

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Chronic neuropsychiatric sequelae of SARS-CoV-2: Protocol and methods from the Alzheimer's Association Global Consortium., Gabriel A de Erausquin, Heather Snyder, Traolach S Brugha, Sudha Seshadri, Maria Carrillo, Rajesh Sagar, Yueqin Huang, Charles Newton, Carmela Tartaglia, Charlotte Teunissen, Krister Håkanson, Rufus Akinyemi, Kameshwar Prasad, Giovanni D'Avossa, Gabriela Gonzalez-Aleman, Akram Hosseini, George D Vavougios, Perminder Sachdev, John Bankart, Niels Peter Ole Mors, Richard Lipton, Mindy Katz, Peter T Fox, Mohammad Zia Katshu, M Sriram Iyengar, Galit Weinstein, Hamid R Sohrabi, Rachel Jenkins, Dan J Stein, Jacques Hugon, Venetsanos Mavreas, John Blangero, Carlos Cruchaga, Murali Krishna, Ovais Wadoo, Rodrigo Becerra, Igor Zwir, William T Longstreth, Golo Kroenenberg, Paul Edison, Elizabeta Mukaetova-Ladinska, Ekkehart Staufenberg, Mariana Figueredo-Aguiar, Agustín Yécora, Fabiana Vaca, Hernan P Zamponi, Vincenzina Lo Re, Abdul Majid, Jonas Sundarakumar, Hector M Gonzalez, Mirjam I Geerlings, Ingmar Skoog, Alberto Salmoiraghi, Filippo Martinelli Boneschi, Vibuthi N Patel, Juan M Santos, Guillermo Rivera Arroyo, Antonio Caballero Moreno, Pascal Felix, Carla Gallo, Hidenori Arai, Masahito Yamada, Takeshi Iwatsubo, Malveeka Sharma, Nandini Chakraborty, Catterina Ferreccio, Dickens Akena, Carol Brayne, Gladys Maestre, Sarah Williams Blangero, Luis I Brusco, Prabha Siddarth, Timothy M Hughes, Alfredo Ramírez Zuñiga, Joseph Kambeitz, Agustin Ruiz Laza, Norrina Allen, Stella Panos, David A Merrill, Agustín Ibáñez, Debby Tsuang, Nino Valishvili, Srishti Shrestha, Sophia Wang, Vasantha Padma, Kaarin J Anstey, Vijayalakshmi Ravindrdanath, Kaj Blennow, Paul Mullins, Emilia Łojek, Anand Pria, Thomas H Mosley, Penny Gowland, Timothy D Girard, Richard Bowtell, and Farhaan S Vahidy

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Clinically Important Difference: 4 Tips Toward a Better Understanding., Joseph R Dettori, Daniel C Norvell, and Jens R Chapman

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Machine learning in clinical diagnosis, prognostication, and management of acute traumatic spinal cord injury (SCI): A systematic review., Nicholas Dietz, Vaitheesh Jaganathan, Victoria Alkin, Jersey Mettille, Maxwell Boakye, and Doniel Drazin

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Patient satisfaction after multiple revision surgeries for adult spinal deformity., Wesley M Durand, Alan H Daniels, Kevin DiSilvestro, Renaud Lafage, Bassel G Diebo, Peter G Passias, Han Jo Kim, Themistocles Protopsaltis, Virginie Lafage, Justin S Smith, Christopher I Shaffrey, Munish C Gupta, Eric O Klineberg, Frank Schwab, Jeffrey L Gum, Gregory M Mundis, Robert K Eastlack, Khaled Kebaish, Alex Soroceanu, Richard A Hostin, Douglas Burton, Shay Bess, Christopher P Ames, Robert A Hart, D Kojo Hamilton, and International Spine Study Group

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Low-Density Pedicle Screw Constructs Are Associated With Lower Incidence of Proximal Junctional Failure in Adult Spinal Deformity Surgery., Wesley M Durand, Kevin J DiSilvestro, Han Jo Kim, David K Hamilton, Renaud Lafage, Peter G Passias, Themistocles S Protopsaltis, Virginie Lafage, Justin S Smith, Christopher I Shaffrey, Munish C Gupta, Eric O Klineberg, Frank J Schwab, Jeffrey L Gum, Gregory M Mundis, Robert K Eastlack, Khaled M Kebaish, Alexandra Soroceanu, Richard A Hostin, Douglas C Burton, Shay Bess, Christopher P Ames, Robert A Hart, Alan H Daniels, and International Spine Study Group

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The Emergence of Virtual Tumor Boards in Neuro-Oncology: Opportunities and Challenges., Chukwuyem Ekhator, Santosh Kesari, Ramya Tadipatri, Ekokobe Fonkem, and Jai Grewal

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Operative treatment outcomes for adult cervical deformity: a prospective multicenter assessment with mean 3-year follow-up., Elias Elias, Shay Bess, Breton G Line, Virginie Lafage, Renaud Lafage, Eric Klineberg, Han Jo Kim, Peter Passias, Zeina Nasser, Jeffrey L Gum, Khaled Kebaish, Robert Eastlack, Alan H Daniels, Gregory Mundis, Richard Hostin, Themistocles S Protopsaltis, Alex Soroceanu, D Kojo Hamilton, Michael P Kelly, Munish Gupta, Robert A Hart, Frank J Schwab, Douglas Burton, Christopher P Ames, Christopher I Shaffrey, and Justin S Smith

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Outcomes of operative treatment for adult spinal deformity: a prospective multicenter assessment with mean 4-year follow-up., Elias Elias, Shay Bess, Breton Line, Virginie Lafage, Renaud Lafage, Eric Klineberg, Han Jo Kim, Peter G Passias, Zeina Nasser, Jeffrey L Gum, Khal Kebaish, Robert Eastlack, Alan H Daniels, Gregory Mundis, Richard Hostin, Themistocles S Protopsaltis, Alex Soroceanu, D Kojo Hamilton, Michael P Kelly, Munish Gupta, Robert A Hart, Frank J Schwab, Douglas Burton, Christopher P Ames, Christopher I Shaffrey, and Justin S Smith

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Compassionate-use pocapavir and immunoglobulin therapy for treatment of rituximab-associated enterovirus meningoencephalitis., Samantha Epstein, Riddhi Thakkar, Kathryn T Fong, James Ng, David R Bearden, Nischay Mishra, Kiran T Thakur, and Claire S Riley

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How I treat brain metastases of melanoma., Z Eroglu, T O Topcu, H M Yu, and K A Margolin

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Erratum to 'Conversion From Knee Arthrodesis Back to Arthroplasty: A Particular Challenge in Combination With Fungal Periprosthetic Joint Infection' [Arthroplasty Today 6 (2020) 1038-1044]., Sven Frieler, Emre Yilmaz, Ryan Goodmanson, Yannik Hanusrichter, Thomas A Schildhauer, and Hinnerk Baecker

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Could bipolar depressed patients respond better to rTMS than unipolar depressed patients? A naturalistic, observational study., Larissa Gama-Chonlon, James M Scanlan, and Rebecca M Allen

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Differentiation of Subjective Cognitive Decline, Mild Cognitive Impairment, and Dementia Using qEEG/ERP-Based Cognitive Testing and Volumetric MRI in an Outpatient Specialty Memory Clinic., Aarthi S Ganapathi, Ryan M Glatt, Tess H Bookheimer, Emily S Popa, Morgan L Ingemanson, Casey J Richards, John F Hodes, Kyron P Pierce, Colby B Slyapich, Fatima Iqbal, Jenna Mattinson, Melanie G Lampa, Jaya M Gill, Ynez M Tongson, Claudia L Wong, Mihae Kim, Verna R Porter, Santosh Kesari, Somayeh Meysami, Karen J Miller, Jennifer E Bramen, David A Merrill, and Prabha Siddarth

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Functional status at 30 and 90 days after mild ischaemic stroke., Hannah Gardener, Leo A Romano, Eric E Smith, Iszet Campo-Bustillo, Yosef Khan, Sofie Tai, Nikesha Riley, Ralph L Sacco, Pooja Khatri, Heather M Alger, Brian Mac Grory, Deepak Gulati, Navdeep S Sangha, Karin E Olds, Curtis G Benesch, Adam G Kelly, Scott S Brehaut, Amit Kansara, Lee H Schwamm, and Jose G Romano

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Prevalence of dementia and mild cognitive impairment in indigenous Bolivian forager-horticulturalists., Margaret Gatz, Wendy J Mack, Helena C Chui, E Meng Law, Giuseppe Barisano, M Linda Sutherland, James D Sutherland, Daniel Eid Rodriguez, Raul Quispe Gutierrez, Juan Copajira Adrian, Jesus Bani Cuata, Amy R Borenstein, Ellen E Walters, Andrei Irimia, Christopher J Rowan, L Samuel Wann, Adel H Allam, Randall C Thompson, Michael Miyamoto, David E Michalik, Daniel K Cummings, Edmond Seabright, Angela R Garcia, Paul L Hooper, Thomas S Kraft, Caleb E Finch, Gregory S Thomas, Jonathan Stieglitz, Benjamin C Trumble, Michael D Gurven, and Hillard Kaplan

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Video game rehabilitation for outpatient stroke (VIGoROUS): A multi-site randomized controlled trial of in-home, self-managed, upper-extremity therapy., Lynne V Gauthier, Deborah S Nichols-Larsen, Gitendra Uswatte, Nancy Strahl, Marie Simeo, Rachel Proffitt, Kristina Kelly, Roger Crawfis, Edward Taub, David Morris, Linda Pax Lowes, Victor Mark, and Alexandra Borstad

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A case of recurrent aneurysm resulting from dual antiplatelet plus anticoagulation after confirmed aneurysm closure following coil-assisted flow diversion., Thomas R Geisbush, Benjamin Pulli, Dylan N Wolman, Arjun V Pendharkar, and Nicholas A Telischak

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Qualitative Evaluation of Educational Content on Lateral Spine Surgery YouTube™ Demonstrations., Periklis Godolias, Kaarina Charlot, Angela Tran, Jonathan Plümer, Charlotte Cibura, Zeyad Daher, Marcel Dudda, Thomas A Schildhauer, Jens Chapman, and Rod J Oskouian

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Safety of Tumor Treating Fields (TTFields) therapy in pediatric patients with malignant brain tumors: Post-marketing surveillance data., Stewart Goldman, Ashley Margol, Eugene I Hwang, Kazuhiro Tanaka, Bogdana Suchorska, John R Crawford, and Santosh Kesari

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A double-blind, placebo-controlled, single-ascending-dose intravenous infusion study of rHIgM22 in subjects with multiple sclerosis immediately following a relapse., Benjamin M Greenberg, J D Bowen, Enrique Alvarez, Moses Rodriguez, Anthony O Caggiano, Arthur E Warrington, Ping Zhao, and Andrew Eisen

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Impact of neurofibromatosis type 1 in an adult community population., Timothy A Gregory, Peter Simon B Molina, Gregory D Phillips, and John W Henson

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Prospective biomarker study in newly diagnosed glioblastoma: Cyto-C clinical trial., Corinne E Griguer, Claudia R Oliva, Christopher S Coffey, Merit E Cudkowicz, Robin A Conwit, Anna L Gudjonsdottir, Dixie J Ecklund, Janel K Fedler, Tina M Neill-Hudson, Louis B Nabors, Melanie Benge, James R Hackney, Marianne Chase, Timothy P Leonard, Toral Patel, Howard Colman, Macarena de la Fuente, Rekha Chaudhary, Karen Marder, Teri Kreisl, Nimish Mohile, Milan G Chheda, Katharine McNeill, Priya Kumthekar, Aclan Dogan, Jan Drappatz, Vinay Puduvalli, Agnes Kowalska, Jerome J Graber, Elizabeth Gerstner, Stephen Clark, Michael Salacz, and James Markert

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Clinical Course of Two Patients with COVID-19 Respiratory Failure After Administration of the Anticancer Small Molecule, RRx-001., Terese Catherine Hammond, Raymond C Lee, Bryan Oronsky, Tony R Reid, Scott Caroen, Tiffany M Juarez, Jaya Gill, Annie Heng, and Santosh Kesari

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Is It Time to Create Training Pathways Allowing Earlier Subspecialization within the "House of Orthopaedics"?: AOA Critical Issues., Robert A Hart, Alan H Daniels, Kalpit Shah, A Annunziato Amendola, Christopher D Harner, L Lawrence Marsh, Keith Kenter, and Serena Hu

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Manifestations of Alzheimer's disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90., Laura M Heath, John C Earls, Andrew T Magis, Sergey A Kornilov, Jennifer C Lovejoy, Cory C Funk, Noa Rappaport, Benjamin A Logsdon, Lara M Mangravite, Brian W Kunkle, Eden R Martin, Adam C Naj, Nilüfer Ertekin-Taner, Todd E Golde, Leroy Hood, Nathan D Price, and Alzheimer’s Disease Genetics Consortium

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Clinical Experiences of 3-Dimensional Biportal Endoscopic Spine Surgery for Lumbar Degenerative Disease., Dong Hwa Heo, Ji Yeon Kim, Jeong-Yoon Park, Jin Sung Kim, Hyeun Sung Kim, Jeffrey R Roh, Choon Keun Park, and Hungtae Chung

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P4 Medicine & What 21st Century Medicine Should Be, Leroy Hood

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Deletion of Abi3/Gngt2 influences age-progressive amyloid β and tau pathologies in distinctive ways., Kristen R Ibanez, Karen N McFarland, Jennifer Phillips, Mariet Allen, Christian B Lessard, Lillian Zobel, Elsa Gonzalez De La Cruz, Shivani Shah, Quan Vo, Xue Wang, Zachary Quicksall, Daniel Ryu, Cory C Funk, Nilüfer Ertekin-Taner, Stefan Prokop, Todd E Golde, and Paramita Chakrabarty

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Perceived utility of electrodiagnostic testing in critical illness myopathy and polyneuropathy: A survey of intensive care unit providers., Michael Isfort, Bryan J McVerry, Lori Shutter, Minji Kim, and David Lacomis

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Vasoplegia Following Complex Spine Surgery: Incidence and Risk., Basem Ishak, Juan N Pulido, Alexander von Glinski, Darius Ansari, Rod J Oskouian, and Jens R Chapman

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How to Give Less Bad News: A Guide to ALS Mimics - David Ivanick, MD, David Ivanick

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Cervical Spine Research Society-Cervical Stiffness Disability Index (CSRS-CSDI): Validation of a Novel Scoring System Quantifying the Effect of Postarthrodesis Cervical Stiffness on Patient Quality of Life., Andrew S Jack, Erik Hayman, Clifford Pierre, Wyatt L Ramey, Christopher D Witiw, Rod J Oskouian, Alan H Daniels, Andrew Pugley, Kojo Hamilton, Christopher P Ames, Jens R Chapman, Zoher Ghogawala, and Robert A Hart

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Agent-based computational modeling of glioblastoma predicts that stromal density is central to oncolytic virus efficacy., Adrianne L Jenner, Munisha Smalley, David Goldman, William F Goins, Charles Cobbs, Ralph B Puchalski, E Antonio Chiocca, Sean Lawler, Paul Macklin, Aaron Goldman, and Morgan Craig

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Health Equity: What the Neuroradiologist Needs to Know., J E Jordan and G B McGinty

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The validity, responsiveness, and score interpretation of the PROMISnq Physical Function - Multiple Sclerosis 15a short form in multiple sclerosis., Paul Kamudoni, Dagmar Amtmann, Jeffrey Johns, Karon F Cook, Rana Salem, Sam Salek, Jana Raab, Rod Middleton, P Repovic, Kevin N Alschuler, Gloria von Geldern, Annette Wundes, Amy Barrett, Oyebimpe Olayinka-Amao, and Christian Henke

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Treatment of nonsurgical refractory back pain with high-frequency spinal cord stimulation at 10 kHz: 12-month results of a pragmatic, multicenter, randomized controlled trial., Leonardo Kapural, Jessica Jameson, Curtis Johnson, Daniel Kloster, Aaron Calodney, Peter Kosek, Julie Pilitsis, Markus Bendel, Erika Petersen, Chengyuan Wu, Taissa Cherry, Shivanand P Lad, Cong Yu, Dawood Sayed, Johnathan Goree, Mark K Lyons, Andrew Sack, Diana Bruce, Frances Rubenstein, Rose Province-Azalde, David Caraway, and Naresh P Patel

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A Case Report: Splenium of the Corpus Callosum Infarct Associated With COVID-19., David A Karp, Gabriel Beaudoin, and Robert A Egan

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Tenecteplase implementation for ischemic stroke at a large tertiary medical center, Laura Kays, Bryce Winn, and Aimee Doyle

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Psychedelic-Assisted Therapy and Psychedelic Science: A Review and Perspective on Opportunities in Neurosurgery and Neuro-Oncology., Daniel F Kelly, Keith Heinzerling, Akanksha Sharma, Shanthi Gowrinathan, Karina Sergi, and Regin Jay Mallari

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A preliminary safety assessment of vertebral augmentation with 32 P brachytherapy bone cement, Joyce H Keyak, Mando L Eijansantos, Katherine G Rosecrance, Daniel Wong, Sayeh Feizi, Aleen L Meldosian, Pranav Peddinti, Clifford M Les, Harry B Skinner, and Varun Sehgal

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Clinical and Economic Profile of Homeless Young Adults with Stroke in the United States, 2002-2017., Safi U Khan, Siva H Yedlapati, Muhammad Zia Khan, Salim S Virani, Michael J Blaha, Garima Sharma, John E Jordan, Bita A Kash, Farhaan S Vahidy, Adeel Arshad, Elias Mossialos, and Khurram Nasir

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An atypical clinical course of a 71-year-old man with right arm weakness and ataxia., Pravin Khemani, Michael Elliott, and Todd Levine

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Quality of life after long-term biochemical control of acromegaly., Allison Kimball, Laura E Dichtel, Kevin C J Yuen, Whitney W Woodmansee, Melanie S Haines, Lisa B Nachtigall, Brooke Swearingen, Pamela Jones, Nicholas A Tritos, Julie L Sharpless, Ursula B Kaiser, Anu Gerweck, and Karen K Miller

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Minimally Invasive Techniques for Facial Rejuvenation Utilizing Polydioxanone Threads., Amit Kochhar, Parvesh Kumar, and Kian Karimi

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The timed 25-foot walk is a more sensitive outcome measure than the EDSS for PPMS trials: an analysis of the PROMISE clinical trial dataset., Marcus W Koch, Jop Mostert, P Repovic, J D Bowen, Jacynthe Comtois, Eva Strijbis, Bernard Uitdehaag, and Gary Cutter

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The nine hole peg test as an outcome measure in progressive MS trials., Marcus W Koch, P Repovic, Jop Mostert, J D Bowen, Jacynthe Comtois, Eva Strijbis, Bernard Uitdehaag, and Gary Cutter

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Evolution of the AO Spine Sacral and Pelvic Classification System: a systematic review., Barry Ting Sheen Kweh, Jin W Tee, F Cumhur Oner, Klaus J Schnake, Emiliano N Vialle, Frank Kanziora, Shanmuganathan Rajasekaran, Marcel Dvorak, Jens R Chapman, Lorin M Benneker, Gregory Schroeder, and Alexander R Vaccaro

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The AO spine upper cervical injury classification system: Do work setting or trauma center affiliation affect classification accuracy or reliability?, Mark J Lambrechts, Gregory D Schroeder, Brian A Karamian, Jose A Canseco, Richard Bransford, Cumhur Oner, Lorin M Benneker, Frank Kandziora, Rajasekaran Shanmuganathan, Rishi Kanna, Andrei F Joaquim, Jens R Chapman, Emiliano Vialle, Mohammad El-Sharkawi, Marcel Dvorak, Klaus Schnake, Christopher K Kepler, and Alexander R Vaccaro

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Global Validation of the AO Spine Upper Cervical Injury Classification: Geographic Region Affects Reliability and Reproducibility., Mark J Lambrechts, Gregory D Schroeder, Brian A Karamian, Jose A Canseco, Richard Bransford, Cumhur Oner, Lorin M Benneker, Frank Kandziora, Rajasekaran Shanmuganathan, Rishi Kanna, Andrei F Joaquim, Jens R Chapman, Emiliano Vialle, Mohammad El-Sharkawi, Marcel Dvorak, Klaus Schnake, Christopher K Kepler, Alexander R Vaccaro, and AO Spine Upper Cervical Injury Classification International Members

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Recent Advances in RNA Therapy and Its Carriers to Treat the Single-Gene Neurological Disorders., Ming-Jen Lee, Inyoul Lee, and Kai Wang

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Radiological Features in Type II Odontoid Fractures in Older Adults After High- and Low-Energy Trauma., Pavlina Lenga, Mohammed Issa, Lennart Krull, Karl Kiening, Andreas W Unterberg, Till Schneider, Rod J Oskouian, Jens R Chapman, and Basem Ishak

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Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial., Linda M Liau, Keyoumars Ashkan, Steven Brem, Jian L Campian, John E Trusheim, Fabio M Iwamoto, David D Tran, George Ansstas, Charles S Cobbs, Jason A Heth, Michael E Salacz, Stacy D'Andre, Robert D Aiken, Yaron A Moshel, Joo Y Nam, Clement P Pillainayagam, Stephanie A Wagner, Kevin A Walter, Rekha Chaudary, Samuel A Goldlust, Ian Y Lee, Daniela A Bota, Heinrich Elinzano, Jai Grewal, Kevin Lillehei, Tom Mikkelsen, Tobias Walbert, Steven Abram, Andrew J Brenner, Matthew G Ewend, Simon Khagi, Darren S Lovick, Jana Portnow, Lyndon Kim, William G Loudon, Nina L Martinez, Reid C Thompson, David E Avigan, Karen L Fink, Francois J Geoffroy, Pierre Giglio, Oleg Gligich, Dietmar Krex, Scott M Lindhorst, Jose Lutzky, Hans-Jörg Meisel, Minou Nadji-Ohl, Lhagva Sanchin, Andrew Sloan, Lynne P Taylor, Julian K Wu, Erin M Dunbar, Arnold B Etame, Santosh Kesari, David Mathieu, David E Piccioni, David S Baskin, Michel Lacroix, Sven-Axel May, Pamela Z New, Timothy J Pluard, Steven A Toms, Victor Tse, Scott Peak, John L Villano, James D Battiste, Paul J Mulholland, Michael L Pearlman, Kevin Petrecca, Michael Schulder, Robert M Prins, Alton L Boynton, and Marnix L Bosch

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Vagus nerve stimulation paired with rehabilitation for stroke: Implantation experience from the VNS-REHAB trial., Charles Y Liu, Jonathan Russin, David P Adelson, Alistair Jenkins, Omar Hilmi, Benjamin Brown, Bradley Lega, Tony Whitworth, Dev Bhattacharyya, Theodore H Schwartz, Vibhor Krishna, Ziv Williams, Christopher Uff, Jon Willie, Caitlin Hoffman, William A Vandergrift, Achal Singh Achrol, Rushna Ali, Peter Konrad, Joseph Edmonds, Daniel Kim, Pragnesh Bhatt, Brent W Tarver, David Pierce, Ravi Jain, Chester Burress, Reema Casavant, Cecília N Prudente, and Navzer D Engineer

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Treatment of Cushing's Disease with Pituitary-Targeting Seliciclib., Ning Ai Liu, Anat Ben-Shlomo, John D Carmichael, Christina Wang, Ronald S Swerdloff, Anthony P Heaney, Garni Barkhoudarian, Daniel Kelly, Mazen Noureddin, Lin Lu, Manish Desai, Yana Stolyarov, Kevin Yuen, Adam N Mamelak, James Mirocha, Mourad Tighiouart, and Shlomo Melmed

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A scalable and modular automated pipeline for stitching of large electron microscopy datasets., Gayathri Mahalingam, Russel Torres, Daniel Kapner, Eric T Trautman, Tim Fliss, Shamishtaa Seshamani, Eric Perlman, Rob Young, Samuel Kinn, JoAnn Buchanan, Marc M Takeno, Wenjing Yin, Daniel J Bumbarger, Ryder P Gwinn, Julie Nyhus, Ed Lein, Steven J Smith, R Clay Reid, Khaled A Khairy, Stephan Saalfeld, Forrest Collman, and Nuno Macarico da Costa

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Disruption of cellular iron homeostasis by, Nunziata Maio, Russell P Saneto, Richard Steet, Márcio A Sotero de Menezes, Cindy Skinner, and Tracey A Rouault

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Handgrip Strength Is Related to Hippocampal and Lobar Brain Volumes in a Cohort of Cognitively Impaired Older Adults with Confirmed Amyloid Burden., Somayeh Meysami, Cyrus A Raji, Ryan M. Glatt, Emily S Popa, Aarthi Ganapathi, Tess Bookheimer, Colby B Slyapich, Kyron P Pierce, Casey J Richards, Melanie G Lampa, Jaya Mini Gill, Molly Rapozo, John F Hodes, Ynez M Tongson, Claudia L Wong, Mihae Kim, Verna R Porter, Scott Kaiser, Stella Panos, Richelin V Dye, Karen J Miller, Susan Y Bookheimer, Neil A Martin, Santosh Kesari, Daniel F Kelly, Jennifer Bramen, Prabha Siddarth, and David A Merrill

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Predicting poor response to anti-coagulation therapy in cerebral venous thrombosis using a simple clinical-radiological score., Victor Montalvan, Gabriel Neves, Tulio Bueso, Riichi Ota, Saji Bushnaq, Thomas Windisch, and Saif Bushnaq

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Patient-Reported Outcomes and Predictive Factors following Focused Ultrasound Thalamotomy for Essential Tremor., Shayan Moosa, Andrew Craver, David Asuzu, Matthew Eames, Tony R Wang, and William Jeffrey Elias

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Cerebral Regional Tissue Oxygenation as Surrogate for Blood Loss in Nonhuman Primate Models of Shock., Clifford G Morgan, Leslie E Neidert, Emily N Hathaway, Michael M Tiller, Sylvain Cardin, and Jacob J Glaser

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Spontaneous Resolution of Aberrant Cerebellar Tonsil Movement in a Patient with Improving Chiari I Malformation., Ryan Morgan, Reagan A Collins, Taha Hassan, Roy Jacob, and Laszlo Nagy

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GPR17 Signaling Activation by CHBC Agonist Induced Cell Death via Modulation of MAPK Pathway in Glioblastoma., Phung Nguyen, Phuong Doan, Akshaya Murugesan, Thiyagarajan Ramesh, Tatu Rimpilainen, Nuno R Candeias, Olli Yli-Harja, and Meenakshisundaram Kandhavelu

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Anterior vs Posterior Approach in Multilevel Cervical Spondylotic Myelopathy: A Nationwide Propensity-Matched Analysis of Complications, Outcomes, and Narcotic Use., Ravi S Nunna, Syed Khalid, Ryan G Chiu, Rown Parola, Richard G Fessler, Owoicho Adogwa, and Ankit I Mehta

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Advancing Care and Outcomes for African American Patients With Multiple Sclerosis., Annette F Okai, Annette M Howard, Mitzi J Williams, Justine Brink, Chiayi Chen, tamela stuchiner, Elizabeth Baraban, Grace Jeong, and Stanley Cohan

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Dimethyl Fumarate Delays Multiple Sclerosis in Radiologically Isolated Syndrome., Darin T Okuda, Orhun Kantarci, Christine Lebrun-Frénay, Maria Pia Sormani, Christina J Azevedo, Francesca Bovis, Le H Hua, Lilyana Amezcua, Ellen M Mowry, Christophe Hotermans, Jason Mendoza, John S Walsh, Christian von Hehn, Wendy S Vargas, Stacy Donlon, Robert T Naismith, Annette Okai, Gabriel Pardo, Pavle Repovic, Olaf Stüve, Aksel Siva, and Daniel Pelletier

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Minimally invasive pericranial flap harvest through a supraorbital eyebrow craniotomy: Technical note in salvage skull base reconstruction., Madeline G Olson, Michael B Avery, Shauna Javaherian, Walavan Sivakumar, Daniel F Kelly, Chester Griffiths, and Garni Barkhoudarian

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Cerebral blood flow dynamics before, during, and after seizures from epilepsy and the periictal state., Kalarickal Oommen and Jonathan Kopel

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The Role of Parenteral Dantrolene in the Contemporary Management of Cerebral Vasospasm in Aneurysmal Subarachnoid Hemorrhage: A Systematic Review., Michael Ortiz, Ravi S Nunna, Kaushik Ravipati, Angela Tran, Adnan I Qureshi, and Farhan Siddiq

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Effect of sodium phenylbutyrate/taurursodiol on tracheostomy/ventilation-free survival and hospitalisation in amyotrophic lateral sclerosis: long-term results from the CENTAUR trial., Sabrina Paganoni, Suzanne Hendrix, Samuel P Dickson, Newman Knowlton, James D Berry, Michael Elliott, Samuel Maiser, Chafic Karam, James B Caress, Margaret Ayo Owegi, Adam Quick, James Wymer, Stephen A Goutman, Daragh Heitzman, Terry D Heiman-Patterson, Carlayne Jackson, Colin Quinn, Jeffrey D Rothstein, Edward J Kasarskis, Jonathan Katz, Liberty Jenkins, Shafeeq S Ladha, Timothy M Miller, Stephen N Scelsa, Tuan H Vu, Christina Fournier, Kristin M Johnson, Andrea Swenson, Namita Goyal, Gary L Pattee, Suma Babu, Marianne Chase, Derek Dagostino, Meghan Hall, Gale Kittle, Mathew Eydinov, Joseph Ostrow, Lindsay Pothier, Rebecca Randall, Jeremy M Shefner, Alexander V Sherman, Eric Tustison, Prasha Vigneswaran, Hong Yu, Joshua Cohen, Justin Klee, Rudolph Tanzi, Walter Gilbert, Patrick Yeramian, and Merit Cudkowicz

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Molecular alterations associated with improved outcome in patients with glioblastoma treated with Tumor-Treating Fields., Manjari Pandey, Joanne Xiu, Sandeep Mittal, Jia Zeng, Michelle Saul, Santosh Kesari, Amir Azadi, Herbert Newton, Karina Deniz, Katherine Ladner, Ashley Sumrall, W Michael Korn, and Emil Lou

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Examination of the Economic Burden of Frailty in Patients With Adult Spinal Deformity Undergoing Surgical Intervention., Peter G Passias, Waleed Ahmad, Nicholas Kummer, Renaud Lafage, Virginie Lafage, Khaled Kebaish, Alan Daniels, Eric Klineberg, Alex Soroceanu, Jeffrey Gum, Breton Line, Robert A Hart, Douglas Burton, Robert Eastlack, Amit Jain, Justin S Smith, Christopher P Ames, Christopher Shaffrey, Frank Schwab, Richard Hostin, and Shay Bess

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Development of Risk Stratification Predictive Models for Cervical Deformity Surgery., Peter G Passias, Waleed Ahmad, Cheongeun Oh, Bailey Imbo, Sara Naessig, Katherine Pierce, Virginie Lafage, Renaud Lafage, D Kojo Hamilton, Themistocles S Protopsaltis, Eric O Klineberg, Jeffrey Gum, Andrew J Schoenfeld, Breton Line, Robert A Hart, Douglas C Burton, Shay Bess, Frank J Schwab, Justin S Smith, Christopher I Shaffrey, Christopher P Ames, and International Spine Study Group

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Changes in health-related quality of life measures associated with degree of proximal junctional kyphosis., Peter G Passias, Nicholas J Frangella, Tyler K Williamson, Kevin A Moattari, Renaud Lafage, Virginie Lafage, Justin S Smith, Khaled M Kebaish, Douglas C Burton, Robert A Hart, Christopher P Ames, Shay Bess, Christopher I Shaffrey, and Frank J Schwab

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Evolution of Adult Cervical Deformity Surgery Clinical and Radiographic Outcomes Based on a Multicenter Prospective Study: Are Behaviors and Outcomes Changing with Experience?, Peter G Passias, Oscar Krol, Kevin Moattari, Tyler K Williamson, Virginie Lafage, Renaud Lafage, Han Jo Kim, Alan Daniels, Bassel Diebo, Themistocles Protopsaltis, Gregory Mundis, Khaled Kebaish, Alexandra Soroceanu, Justin Scheer, D Kojo Hamilton, Eric Klineberg, Andrew J Schoenfeld, Shaleen Vira, Breton Line, Robert Hart, Douglas C Burton, Frank A Schwab, Christopher Shaffrey, Shay Bess, Justin S Smith, Christopher P Ames, and International Spine Study Group

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The Benefit of Addressing Malalignment In Revision Surgery for Proximal Junctional Kyphosis Following ASD Surgery., Peter G Passias, Oscar Krol, Tyler K Williamson, Virginie Lafage, Renaud Lafage, Justin S Smith, Breton Line, Shaleen Vira, Shaina Lipa, Alan Daniels, Bassel Diebo, Andrew Schoenfeld, Jeffrey Gum, Khaled Kebaish, Paul Park, Gregory Mundis, Richard Hostin, Manush Gupta, Robert Eastlack, Neel Anand, Christopher Ames, Robert A Hart, Douglas Burton, Frank J Schwab, Christopher Shaffrey, Eric Klineberg, and Shay Bess

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Improvements in Outcomes and Cost after Adult Spinal Deformity Corrective Surgery between 2008 and 2019., Peter G Passias, Nicholas Kummer, Bailey Imbo, Virginie Lafage, Renaud Lafage, Justin S Smith, Breton Line, Shaleen Vira, Andrew J Schoenfeld, Jeffrey L Gum, Alan H Daniels, Eric O Klineberg, Munish C Gupta, Khaled M Kebaish, Amit Jain, Brian J Neuman, Dean Chou, Leah Y Carreon, Robert A Hart, Douglas C Burton, Christopher I Shaffrey, Christopher P Ames, Frank J Schwab, Richard A Hostin, Shay Bess, and International Spine Study Group

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The Additional Economic Burden of Frailty in Adult Cervical Deformity Patients Undergoing Surgical Intervention., Peter G Passias, Nicholas Kummer, Tyler K Williamson, Waleed Ahmad, Jordan Lebovic, Virginie Lafage, Renaud Lafage, Han Jo Kim, Alan H Daniels, Jeffrey L Gum, Bassel G Diebo, Munish C Gupta, Alexandra Soroceanu, Justin K Scheer, D Kojo Hamilton, Eric O Klineberg, Breton Line, Andrew J Schoenfeld, Robert A Hart, Douglas C Burton, Robert K Eastlack, Gregory M Mundis, Praveen Mummaneni, Dean Chou, Paul Park, Frank J Schwab, Christopher I Shaffrey, Shay Bess, Christopher P Ames, Justin S Smith, and International Spine Study Group

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Highest Achievable Outcomes for Patients Undergoing Cervical Deformity Corrective Surgery by Frailty., Peter G Passias, Nicholas Kummer, Tyler K Williamson, Kevin Moattari, Virginie Lafage, Renaud Lafage, Han Jo Kim, Alan H Daniels, Jeffrey L Gum, Bassel G Diebo, Themistocles S Protopsaltis, Gregory M Mundis, Robert K Eastlack, Alexandra Soroceanu, Justin K Scheer, D Kojo Hamilton, Eric O Klineberg, Breton Line, Robert A Hart, Douglas C Burton, Praveen Mummaneni, Dean Chou, Paul Park, Frank J Schwab, Christopher I Shaffrey, Shay Bess, Christopher P Ames, and Justin S Smith

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Establishment of an Individualized Distal Junctional Kyphosis Risk Index following the Surgical Treatment of Adult Cervical Deformities., Peter G Passias, Sara Naessig, Navraj Sagoo, Lara Passfall, Waleed Ahmad, Renaud Lafage, Virginie Lafage, Shaleen Vira, Andrew J Schoenfeld, Cheongeun Oh, Themistocles Protopsaltis, Han Jo Kim, Alan Daniels, Robert A Hart, Douglas Burton, Eric O Klineberg, Shay Bess, Frank Schwab, Christopher Shaffrey, Christopher P Ames, Justin S Smith, and International Spine Study Group

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Pelvic Non-Response Following Treatment of Adult Spinal Deformity: Influence of Realignment Strategies on Occurrence., Peter G Passias, Katherine E Pierce, Tyler K Williamson, Oscar Krol, Renaud Lafage, Virginie Lafage, Andrew J Schoenfeld, Themistocles S Protopsaltis, Shaleen Vira, Breton Line, Bassel G Diebo, Christopher P Ames, Han Jo Kim, Justin S Smith, Dean Chou, Alan H Daniels, Jeffrey L Gum, Christopher I Shaffrey, Douglas C Burton, Michael P Kelly, Eric O Klineberg, Robert A Hart, Shay Bess, Frank J Schwab, and Munish C Gupta

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Predictive Analytics for Determining Extended Operative Time in Corrective Adult Spinal Deformity Surgery., Peter G Passias, Gregory W Poorman, Dennis Vasquez-Montes, Nicholas Kummer, Gregory Mundis, Neel Anand, Samantha R Horn, Frank A Segreto, Lara Passfall, Oscar Krol, Bassel Diebo, Doug Burton, Aaron Buckland, Michael Gerling, Alex Soroceanu, Robert Eastlack, D Kojo Hamilton, Robert A Hart, Frank Schwab, Virginie Lafage, Christopher Shaffrey, Daniel Sciubba, Shay Bess, Christopher Ames, Eric Klineberg, and International Spine Study Group

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Is frailty responsive to surgical correction of adult spinal deformity? An investigation of sagittal re-alignment and frailty component drivers of postoperative frailty status., Peter G Passias, Frank A Segreto, Kevin A Moattari, Renaud Lafage, Justin S Smith, Breton G Line, Robert K Eastlack, Douglas C Burton, Robert A Hart, Shay Bess, Christopher I Shaffrey, Christopher P Ames, Virginie Lafage, and International Spine Study Group

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Posterior Ischemic Optic Neuropathy Because of Hematologic Malignancy., Ankush U Patel, Uresh S Patel, and Eugene F May

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Clinical and radiographic benefits of skipping C7 instrumentation in posterior cervicothoracic fusion: a retrospective analysis., Saavan Patel, Morteza Sadeh, Matthew K Tobin, Nauman S Chaudhry, C Gragnaniello, and Sergey Neckrysh