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Submissions from 2021

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Radiation dose and fraction in immunotherapy: one-size regimen does not fit all settings, so how does one choose?, Sandra Demaria, Chandan Guha, Jonathan Schoenfeld, Zachary Morris, Arta Monjazeb, Andrew Sikora, Marka Crittenden, Stephen Shiao, Samir Khleif, Seema Gupta, Silvia Chiara Formenti, Bhadrasain Vikram, C Norman Coleman, and Mansoor M Ahmed

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Open-Label Phase II Prospective, Randomized, Controlled Study of Romyelocel-L Myeloid Progenitor Cells to Reduce Infection During Induction Chemotherapy for Acute Myeloid Leukemia., Pinkal M Desai, Janice Brown, Saar Gill, Melham M Solh, Luke P Akard, Jack W Hsu, Celalettin Ustun, Charalambos Andreadis, Olga Frankfurt, James M Foran, John Lister, Gary J Schiller, Matthew J Wieduwilt, John M Pagel, Patrick J Stiff, Delong Liu, Irum Khan, Wendy Stock, Suman Kambhampati, Martin S Tallman, Lawrence Morris, John Edwards, Iskra Pusic, Hagop M Kantarjian, Richard Mamelok, Alicia Wong, Rodney Van Syoc, Lois Kellerman, Swapna Panuganti, Ramkumar Mandalam, Camille N Abboud, and Farhad Ravandi

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Bempegaldesleukin Plus Nivolumab in First-Line Metastatic Melanoma., Adi Diab, Scott S Tykodi, Gregory A Daniels, Michele Maio, Brendan D Curti, Karl D Lewis, Sekwon Jang, Ewa Kalinka, Igor Puzanov, Alexander I Spira, Daniel C Cho, Shanhong Guan, Erika Puente, Tuan Nguyen, Ute Hoch, Sue L Currie, Wei Lin, Mary A Tagliaferri, Jonathan Zalevsky, Mario Sznol, and Michael E Hurwitz

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Disparities in Amputation Rates for Non-metastatic Extremity Soft Tissue Sarcomas and the Impact on Survival., Joshua C Dilday, Daniel W Nelson, Trevan D Fischer, and Melanie Goldfarb

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Alkylaminophenol and GPR17 Agonist for Glioblastoma Therapy: A Combinational Approach for Enhanced Cell Death Activity., Phuong Doan, Phung Nguyen, Akshaya Murugesan, Nuno R Candeias, Olli Yli-Harja, and Meenakshisundaram Kandhavelu

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Targeting Orphan G Protein-Coupled Receptor 17 with T0 Ligand Impairs Glioblastoma Growth., Phuong Doan, Phung Nguyen, Akshaya Murugesan, Kumar Subramanian, Saravanan Konda Mani, Vignesh Kalimuthu, Bobin George Abraham, Brett W Stringer, Kadalmani Balamuthu, Olli Yli-Harja, and Meenakshisundaram Kandhavelu

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First-In-Human, First-In-Class, Phase I Trial of the Fucosylation Inhibitor SGN-2FF in Patients with Advanced Solid Tumors., Khanh T Do, Laura Quan Man Chow, Karen Reckamp, Rachel E Sanborn, Howard Burris, Francisco Robert, D Ross Camidge, Conor E Steuer, John H Strickler, Amy Weise, Jennifer M Specht, Martin Gutierrez, Peter Haughney, Shawna Hengel, Christina Louise Derleth, and Timothy A Yap

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Cancer case trends following the onset of the COVID-19 pandemic: A community-based observational study with extended follow-up., Charles W Drescher, Adam J Bograd, Shu-Ching Chang, Roshanthi Weerasinghe, Ann Vita, and Richard Bryan Bell

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Effect of Use of a Bougie vs Endotracheal Tube With Stylet on Successful Intubation on the First Attempt Among Critically Ill Patients Undergoing Tracheal Intubation: A Randomized Clinical Trial., Brian E Driver, Matthew W Semler, Wesley H Self, Adit A Ginde, Stacy A Trent, Sheetal Gandotra, Lane M Smith, David B Page, Derek J Vonderhaar, Jason R West, Aaron M Joffe, Steven H Mitchell, Kevin C Doerschug, Christopher G Hughes, Kevin High, Janna S Landsperger, Karen E Jackson, Michelle P Howell, Sarah W Robison, John P Gaillard, Micah R Whitson, Christopher M Barnes, Andrew J Latimer, Vikas S Koppurapu, Bret D Alvis, Derek W Russell, Kevin W Gibbs, Li Wang, Christopher J Lindsell, David R Janz, Todd W Rice, Matthew E Prekker, Jonathan D Casey, and BOUGIE Investigators and the Pragmatic Critical Care Research Group

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The Impact of Chronic Kidney Disease in Patients With Locally Advanced Rectal Cancer Treated With Neoadjuvant Chemoradiation., Shaan Dudani, Horia Marginean, Joanna Gotfrit, Patricia A Tang, Jose Gerard Monzon, Kristopher Dennis, Hagen F Kennecke, Erin D Powell, Sam Babak, Winson Y Cheung, and Michael M Vickers

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Neoadjuvant anti-OX40 (MEDI6469) therapy in patients with head and neck squamous cell carcinoma activates and expands antigen-specific tumor-infiltrating T cells., Rebekka Duhen, Carmen Ballesteros-Merino, Alexandra K Frye, Eric Tran, Venkatesh Rajamanickam, Shu-Ching Chang, Yoshinobu Koguchi, Carlo Bifulco, Brady Bernard, Rom Leidner, Brendan Curti, Bernard A Fox, Walter Urba, Richard Bryan Bell, and Andrew D Weinberg

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Neoadjuvant talimogene laherparepvec plus surgery versus surgery alone for resectable stage IIIB-IVM1a melanoma: a randomized, open-label, phase 2 trial., R Dummer, D E Gyorki, J Hyngstrom, A C Berger, R Conry, L Demidov, A Sharma, S A Treichel, H Radcliffe, K S Gorski, A Anderson, E Chan, M Faries, and M I Ross

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Cabozantinib: An evolving therapy for hepatocellular carcinoma., Anthony B El-Khoueiry, Diana L Hanna, Josep Llovet, and Robin Kate Kelley

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Modified RANO, Immunotherapy RANO, and Standard RANO Response to Convection-Enhanced Delivery of IL4R-Targeted Immunotoxin MDNA55 in Recurrent Glioblastoma., Benjamin M Ellingson, John Sampson, Achal Singh Achrol, Manish K Aghi, Krystof Bankiewicz, Chencai Wang, Martin Bexon, Steven Brem, Andrew Brenner, Sajeel Chowdhary, John R Floyd, Seunggu Han, Santosh Kesari, Dina Randazzo, Michael A Vogelbaum, Frank Vrionis, Miroslaw Zabek, Nicholas Butowski, Melissa Coello, Nina Merchant, and Fahar Merchant

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Cryopreserved placental tissue allograft accelerates time to continence following robot-assisted radical prostatectomy., Peter A Elliott, Stephanie Hsiang, Ramkishen Narayanan, James Bierylo, Shu-Ching Chang, Przemyslaw Twardowski, and Timothy G Wilson

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Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of breast cancer., Leisha A Emens, Sylvia Adams, Ashley Cimino-Mathews, Mary L Disis, Margaret E Gatti-Mays, Alice Y Ho, Kevin Kalinsky, Heather L McArthur, Elizabeth A Mittendorf, Rita Nanda, David B Page, Hope S Rugo, Krista M Rubin, Hatem Soliman, Patricia A Spears, Sara M Tolaney, and Jennifer K Litton

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Enhancing the generation of Eomeshi CD8+ T cells augment the efficacy of OX40- and CTLA-4-targeted immunotherapy., Dana A Emerson, Annah S Rolig, and William L. Redmond

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Are There Limits in Explainability of Prognostic Biomarkers? Scrutinizing Biological Utility of Established Signatures., Frank Emmert-Streib, Kalifa Manjang, Matthias Dehmer, Olli Yli-Harja, and Anssi Auvinen

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Current Triple-Negative Breast Cancer Subtypes: Dissecting the Most Aggressive Form of Breast Cancer., Miquel Ensenyat-Mendez, Pere Llinàs-Arias, Javier I J Orozco, Sandra Íñiguez-Muñoz, Matthew P Salomon, Borja Sesé, Maggie L DiNome, and Diego M Marzese

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Comparative analysis of targeted novel therapies in relapsed, refractory chronic lymphocytic leukaemia., Toby A Eyre, Nicole Lamanna, Lindsey E Roeker, Chaitra S Ujjani, Brian T Hill, Paul M Barr, Erick Lansigan, Bruce D Cheson, Maryam Yazdy, John N Allan, Joanna Rhodes, Stephen J Schuster, Chadi Nabhan, Alan Skarbnik, Lori Leslie, Prioty Islam, Katherine Whitaker, Catherine C Coombs, Hande H Tuncer, John M Pagel, Ryan Jacobs, Allison M Winter, Neil Bailey, Andrea Sitlinger, Anna H Schuh, George Follows, Christopher P Fox, Danielle M Brander, Mazyar Shadman, and Anthony R Mato

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Acalabrutinib monotherapy for treatment of chronic lymphocytic leukaemia (ACE-CL-001): analysis of the Richter transformation cohort of an open-label, single-arm, phase 1-2 study., Toby A Eyre, Anna Schuh, William G Wierda, Jennifer R Brown, Paolo Ghia, John M Pagel, Richard R Furman, Jean Cheung, Ahmed Hamdy, Raquel Izumi, Priti Patel, Min Hui Wang, Yan Xu, John C Byrd, and Peter Hillmen

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Challenges and Errors in Genetic Testing: The Fifth Case Series., Meagan B Farmer, Danielle C Bonadies, Holly J Pederson, Kathryn A Mraz, Julie W Whatley, Deanna R Darnes, Jessica Johnson Denton, Diana De Rosa, Alexis Heatherly, Jessica Kenney, Kimberly Lane, Deborah Paul, Renée C Pelletier, Kristen Shannon, Danielle Williams, and Ellen T Matloff

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Challenges and Errors in Genetic Testing: The Fifth Case Series., Meagan B Farmer, Danielle C Bonadies, Holly J Pederson, Kathryn A Mraz, Julie W Whatley, Deanna R Darnes, Jessica Johnson Denton, Diana De Rosa, Alexis Heatherly, Jessica Kenney, Kimberly Lane, Deborah Paul, Renée C Pelletier, Kristen Shannon, Danielle Williams, and Ellen T Matloff

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CD8-targeted PET Imaging of Tumor Infiltrating T cells in Patients with Cancer: A Phase I First-in-Human Study of, Michael D Farwell, Raymond F Gamache, Hasan Babazada, Matthew D Hellmann, James J Harding, Ron Korn, Alessandro Mascioni, William Le, Ian Wilson, Michael S Gordon, Anna M Wu, Gary A Ulaner, Jedd D Wolchok, Michael A Postow, and Neeta A Pandit-Taskar

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NCI Imaging Data Commons., Andrey Fedorov, William J R Longabaugh, David Pot, David A Clunie, Steve Pieper, Hugo J W L Aerts, André Homeyer, Rob Lewis, Afshin Akbarzadeh, Dennis Bontempi, William Clifford, Markus D Herrmann, Henning Höfener, Igor Octaviano, Chad Osborne, Suzanne Paquette, James Petts, Davide Punzo, Madelyn Reyes, Daniela P Schacherer, Mi Tian, George White, Erik Ziegler, Ilya Shmulevich, Todd Pihl, Ulrike Wagner, Keyvan Farahani, and Ron Kikinis

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383 Durable responses with intratumoral electroporation of plasmid interleukin 12 plus pembrolizumab in patients with advanced melanoma progressing on an anti-PD-1 antibody: updated data from keynote 695, Pablo Fernandez-Penas, Carmen Ballesteros-Merino, Shawn M. Jensen, Bernard A Fox, and See full list of authors in comments

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Trilaciclib prior to chemotherapy reduces the usage of supportive care interventions for chemotherapy-induced myelosuppression in patients with small cell lung cancer: Pooled analysis of three randomized phase 2 trials., Renata Ferrarotto, Ian Anderson, Balazs Medgyasszay, Maria Rosario García-Campelo, William Edenfield, Trevor M Feinstein, Jennifer M Johnson, Sujith Kalmadi, Philip E Lammers, Alfredo Sanchez-Hernandez, Yili Pritchett, Shannon R Morris, Rajesh K Malik, and Tibor Csőszi

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Updated report of a phase II randomized trial of transoral surgical resection followed by low-dose or standard postoperative therapy in resectable p16+ locally advanced oropharynx cancer: A trial of the ECOG-ACRIN cancer research group (E3311)., Robert L. Ferris, Yael Flammand, Richard Bryan Bell, and See list of authors in comments

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Neoadjuvant nivolumab for patients with resectable HPV-positive and HPV-negative squamous cell carcinomas of the head and neck in the CheckMate 358 trial., Robert L Ferris, William C Spanos, Rom Leidner, Anthony Gonçalves, Uwe M Martens, Chrisann Kyi, William Sharfman, Christine H Chung, Lot A Devriese, Helene Gauthier, Simon I Chiosea, Lazar Vujanovic, Janis M Taube, Julie E Stein, Jun Li, Bin Li, Tian Chen, Adam Barrows, and Suzanne L Topalian

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Associations of practical, emotional, and physical problems with psychosocial distress among cancer patients., Mark William Flanagan, Heather H Goltz, John W Henson, and Matthew Lee Smith

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Immune-related adverse events are associated with improved response, progression-free survival, and overall survival for patients with head and neck cancer receiving immune checkpoint inhibitors., Corey C Foster, Marcus Couey, Sara E Kochanny, Arun Khattri, Rajesh K Acharya, Yi-Hung Carol Tan, Ryan J Brisson, Rom S Leidner, and Tanguy Y Seiwert

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Umbralisib, a Dual PI3Kδ/CK1ε Inhibitor in Patients With Relapsed or Refractory Indolent Lymphoma., Nathan H Fowler, Felipe Samaniego, Wojciech Jurczak, Nilanjan Ghosh, Enrico Derenzini, James A Reeves, Wanda Knopińska-Posłuszny, Chan Y Cheah, Tycel Phillips, Ewa Lech-Maranda, Bruce D Cheson, Paolo F Caimi, Sebastian Grosicki, Lori A Leslie, Julio C Chavez, Gustavo Fonseca, Sunil Babu, Daniel J Hodson, Spencer H Shao, John M Burke, Jeff P Sharman, Jennie Y Law, John M Pagel, Hari P Miskin, Peter Sportelli, Owen A O'Connor, Michael S Weiss, and Pier Luigi Zinzani

Evaluating the cancer surfaceome: a possible strategy to identify targets and monitor immunity, Bernard A Fox

Exploiting Autophagy and the Ubiquitin Pathway to Educate the Immune System and Improve Cancer Immunotherapy, Bernard A Fox

Immunogenic cell death and antigen release, Bernard A Fox

Shared Immunogenic Cancer Antigens in Humans and Combination Immunotherapy Clinical Trials that Exploit Those Antigens, Bernard A Fox

Translation: An Iterative and Team Process – Our Path to the Development of Triplet Cancer Immunotherapy, Bernard A Fox

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Multicenter Evaluation of Survival and Toxicities of Hepatocellular Carcinoma following Radioembolization: Analysis of the RESiN Registry., Shelby Frantz, Lea Matsuoka, Kirubahara Vaheesan, Michael Petroziello, Jafar Golzarian, Eric Wang, Ripal Gandhi, Zach Collins, Jayson Brower, Varun M Rachakonda, Liping Du, Andrew S Kennedy, Daniel Y Sze, Justin Lee, and Daniel B Brown

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Pooled analysis of safety data from clinical trials evaluating acalabrutinib monotherapy in mature B-cell malignancies., Richard R Furman, John C Byrd, Roger G Owen, Susan M O'Brien, Jennifer R Brown, Peter Hillmen, Deborah M Stephens, Nataliya Chernyukhin, Tamara Lezhava, Ahmed M Hamdy, Raquel Izumi, Priti Patel, Marshall Baek, Beth Christian, Martin J S Dyer, Matthew J Streetly, Clare Sun, Simon Rule, Michael Wang, Paolo Ghia, Wojciech Jurczak, John M Pagel, and Jeff P Sharman

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A phase I study of the WT2725 dosing emulsion in patients with advanced malignancies., Siqing Fu, David E Piccioni, Hongtao Liu, Rimas V Lukas, Santosh Kesari, Dawit Aregawi, David S Hong, Kenichiro Yamaguchi, Kate Whicher, Yi Zhang, Yu-Luan Chen, Nagaraju Poola, John Eddy, and David Blum

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Pralsetinib for RET fusion-positive non-small-cell lung cancer (ARROW): a multi-cohort, open-label, phase 1/2 study., Justin F Gainor, Giuseppe Curigliano, Dong-Wan Kim, Dae Ho Lee, Benjamin Besse, Christina S Baik, Robert C Doebele, Philippe A Cassier, Gilberto Lopes, Daniel S W Tan, Elena Garralda, Luis G Paz-Ares, Byoung Chul Cho, Shirish M Gadgeel, Michael Thomas, Stephen V Liu, Matthew H Taylor, Aaron S Mansfield, Viola W Zhu, Corinne Clifford, Hui Zhang, Michael Palmer, Jennifer Green, Christopher D Turner, and Vivek Subbiah

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SGNTGT-001: A phase 1 study of SEA‑TGT, an effector-function enhanced monoclonal antibody (mAb), in advanced malignancies (trial in progress)., Elenda Garralda, Rachel E Sanborn, and See list of authors in comments

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Once weekly selinexor, carfilzomib and dexamethasone in carfilzomib non-refractory multiple myeloma patients., Cristina Gasparetto, Gary J Schiller, Sascha A Tuchman, Natalie S Callander, Muhamed Baljevic, Suzanne Lentzsch, Adriana C Rossi, Rami Kotb, Darrell White, Nizar J Bahlis, Christine I Chen, Heather J Sutherland, Sumit Madan, Richard LeBlanc, Michael Sebag, Christopher P Venner, William Bensinger, Noa Biran, Sonia Ammu, Osnat Ben-Shahar, Andrew DeCastro, Dane Van Domelen, Tianjun Zhou, Chris Zhang, Ohad S Bentur, Jatin Shah, Sharon Shacham, Michael Kauffman, and Brea Lipe

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Patient-Specific Cell Communication Networks Associate With Disease Progression in Cancer., David L Gibbs, Boris Aguilar, Vésteinn Thorsson, Alexander V Ratushny, and Ilya Shmulevich

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Cumulative radiation dose incurred during the management of complex pleural space infection., Christopher R Gilbert, Anee S Jackson, Candice L. Wilshire, Leah C Horslen, Shu-Ching Chang, Adam J Bograd, Eric Vallieres, and Jed A Gorden

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Pleural Drainage Strategy After IPC Placement: A Focused Clinical Review., Christopher R Gilbert and Russell J Miller

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The longitudinal relationship between immune cell profiles and frailty in patients with breast cancer receiving chemotherapy., Nikesha Gilmore, Supriya Mohile, Lianlian Lei, Eva Culakova, Mostafa Mohamed, Allison Magnuson, Kah Poh Loh, Ronald Maggiore, Elizabeth Belcher, Alison Conlin, Lora Weiselberg, Mary Ontko, and Michelle Janelsins

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Identifying the miRNA Signature Association with Aging-Related Senescence in Glioblastoma., Mutharasu Gnanavel, Akshaya Murugesan, Saravanan Konda Mani, Olli Yli-Harja, and Meenakshisundaram Kandhavelu

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Outreach: Preliminary safety and efficacy results from a phase 2 study of lisocabtagene maraleucel (liso-cel) in the nonuniversity setting., John E Godwin, Bassam I. Mattar, and See list of authors in comments

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Outreach: Results from a Phase 2 Study of Lisocabtagene Maraleucel (liso-cel) Administered As Inpatient (Inpt) or Outpatient (Outpt) Treatment in the Nonuniversity Setting in Patients (Pts) with R/R Large B-Cell Lymphoma (LBCL), John E Godwin and See full list of authors in comments

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Assessing the risk of thromboembolism in cancer patients receiving immunotherapy., Abhishek Goel, Arjun Khorana, Thomas Kartika, Sonia Gowda, Derrick L Tao, Rajat Thawani, and Joseph J Shatzel

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"Young children are not the same as adolescents when it comes to treating thyroid cancer"., Melanie Goldfarb, Emily Christison-Lagay, Jeff Rastatter, and Jonathan Wasserman

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Perspectives on COVID-19 and cancer immunotherapy: a review series., Jason D Goldman and Paolo Antonio Ascierto

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COVID-19 in immunocompromised populations: implications for prognosis and repurposing of immunotherapies., Jason D Goldman, Philip C Robinson, Thomas S Uldrick, and Per Ljungman

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The chronic lymphocytic leukemia comorbidity index (CLL-CI): a three-factor comorbidity model., Max J Gordon, Andy Kaempf, Andrea Sitlinger, Geoffrey Shouse, Matthew Mei, Danielle M Brander, Tareq Salous, Brian T Hill, Hamood Alqahtani, Michael Choi, Michael C Churnetski, Jonathon B Cohen, Deborah M Stephens, Tanya Siddiqi, Xavier Rivera, Daniel Persky, Paul Wisnewski, Krish Patel, Mazyar Shadman, Byung Park, and Alexey V Danilov

The Dynamics of pre-existing T cells in tumors and the effects of radiation therapy, M Gough

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Adult pilocytic astrocytoma in the molecular era: a comprehensive review., Timothy A Gregory, Lyndon B Chumbley, John W Henson, and Brett J Theeler

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Unique Dermoscopic and Histopathologic Features of Melanoma Arising in a Patient With BAP1 Tumor Predisposition Syndrome., Eric A Grisham, Joseph Tadros, and Emily Smith

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Letter to the Editor: PET/CT in Locally Advanced Breast Cancer: Time for a Guideline Change?, David Groheux, Elif Hindié, Marc Espié, and Gary A Ulaner

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Germinal center reactions in tertiary lymphoid structures associate with neoantigen burden, humoral immunity and long-term survivorship in pancreatic cancer., Andrew J Gunderson, Venkatesh Rajamanickam, Cynthia Bui, Brady Bernard, Joanna Pucilowska, Carmen Ballesteros-Merino, Mark Schmidt, Kayla McCarty, Michaela Philips, Brian D. Piening, Christopher Dubay, Terry R Medler, Phillipa Newell, Paul D Hansen, Eric Tran, Ephraim Tang, Carlo Bifulco, Marka R Crittenden, Michael J. Gough, and Kristina H Young

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Single-Cell Profiling of Fatty Acid Uptake Using Surface-Immobilized Dendrimers., Zhili Guo, Hanjun Cheng, Zhonghan Li, Shiqun Shao, Priyanka Sarkar, Siwen Wang, Rohit Chaudhuri, Nicole G Perkins, Fei Ji, Wei Wei, and Min Xue

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Debris-stimulated tumor growth: a Pandora's box?, Victoria M Haak, Sui Huang, and Dipak Panigrahy

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Robotic surgical management of sigmoid colon cancer in pregnancy: A case series., Edward R Hagen, Leigh Gerson, Laila Rashidi, and Amir Bastawrous

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Outcomes Among Classical Hodgkin Lymphoma Patients After an Interim PET Scan: A Real-World Experience., Muhammad Saad Hamid, Sarah C Rutherford, Hyejeong Jang, Seongho Kim, Krish Patel, Nancy L Bartlett, Mary-Kate Malecek, Marcus P Watkins, Kami J Maddocks, David A Bond, Tatyana A Feldman, Gabriela Magarelli, Ranjana H Advani, Michael A Spinner, Andrew M Evens, Mansi Shah, Sairah Ahmed, Deborah M Stephens, Pamela Allen, Michael T Tees, Reem Karmali, Bruce D Cheson, Maryam Sarraf Yazdy, Christopher Strouse, Neil Bailey, John M Pagel, and Radhakrishnan Ramchandren

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Clinical implementation of automated treatment planning for whole-brain radiotherapy., Eun Young Han, Carlos E Cardenas, Callistus Nguyen, Donald Hancock, Yao Xiao, Raymond Mumme, Laurence E Court, Dong Joo Rhee, Tucker J Netherton, Jing Li, Debra Nana Yeboa, Chenyang Wang, Tina M Briere, Peter Balter, Mary K Martel, and Zhifei Wen

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Hepatic Plexus Nerve Block for Microwave Ablation of Hepatic Tumors., Frank Hao, Navid Eghbalieh, Alexandra So, and Edward Wolfgang Lee

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LB180 - Clinical biomarker studies with two fusion-enhanced versions of oncolytic HSV (RP1 and RP2) alone and in combination with nivolumab in cancer patients indicate potent immune activation, Kevin J. Harrington, Francesca Aroldi, Joseph J. Sacco, Mohammed M. Milhem, Brendan Curti, Ari M. Vanderwalde, Scott Baum, Adel Samson, Anna C. Pavlick, Jason A. Chesney, Jiaxin Niu, Terence D. Rhodes, Tawnya L. Bowles, Robert Conry, Anna Olsson-Brown, Douglas E. Laux, Pablo Nenclares, Lavita Menezes, Alex Deterding, Victoria Roulstone, Joan Kyula, Suzanne Thomas, Praveen K. Bommareddy, Selda Samakoglu, Andrea Pirzkall, Robert S. Coffin, and Mark R. Middleton

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The frequency of medical reversals in a cross-sectional analysis of high-impact oncology journals, 2009-2018., Alyson Haslam, Jennifer Gill, Tyler Crain, Diana Herrera-Perez, Emerson Y Chen, Talal Hilal, Myung S Kim, and Vinay Prasad

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The frequency of assessment of progression in randomized oncology clinical trials., Alyson Haslam, Jennifer Gill, and Vinay Prasad

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Correction to: Physician-directed genetic screening to evaluate personal risk for medically actionable disorders: a large multi-center cohort study., Eden V Haverfield, Edward D Esplin, Sienna J Aguilar, Kathryn E Hatchell, Kelly E Ormond, Andrea Hanson-Kahn, Paldeep S Atwal, Sarah Macklin-Mantia, Stephanie Hines, Caron W-M Sak, Steven Tucker, Steven B Bleyl, Peter J Hulick, Ora K Gordon, Lea Velsher, Jessica Y J Gu, Scott M Weissman, Teresa Kruisselbrink, Christopher Abel, Michele Kettles, Anne Slavotinek, Bryce A Mendelsohn, Robert C Green, Swaroop Aradhya, and Robert L Nussbaum

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Physician-directed genetic screening to evaluate personal risk for medically actionable disorders: a large multi-center cohort study., Eden V Haverfield, Edward D Esplin, Sienna J Aguilar, Kathryn E Hatchell, Kelly E Ormond, Andrea Hanson-Kahn, Paldeep S Atwal, Sarah Macklin-Mantia, Stephanie Hines, Caron W-M Sak, Steven Tucker, Steven B Bleyl, Peter J Hulick, Ora K Gordon, Lea Velsher, Jessica Y J Gu, Scott M Weissman, Teresa Kruisselbrink, Christopher Abel, Michele Kettles, Anne Slavotinek, Bryce A Mendelsohn, Robert C Green, Swaroop Aradhya, and Robert L Nussbaum

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Receipt of Tobacco Treatment and One-Year Smoking Cessation Rates Following Lung Cancer Screening in the Veterans Health Administration., Jaimee L Heffner, Scott Coggeshall, Chelle L Wheat, Paul Krebs, Laura C Feemster, Deborah E Klein, Linda Nici, Hannah Johnson, and Steven B Zeliadt

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Bilateral internal iliac branch device with ipsilateral deployment., Jake F Hemingway, Anna Ohlsson, Jason Hurd, and Benjamin W Starnes

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Digital twins for predictive oncology will be a paradigm shift for precision cancer care., Tina Hernandez-Boussard, Paul Macklin, Emily J Greenspan, Amy L Gryshuk, Eric Stahlberg, Tanveer Syeda-Mahmood, and Ilya Shmulevich

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Impact of Molecular Features of Diffuse Large B-Cell Lymphoma on Treatment Outcomes with Anti-CD19 Chimeric Antigen Receptor (CAR) T-Cell Therapy, Brian T. Hill, Neil Bailey, Krish Patel, John M Pagel, and See full list of authors in comments

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First report of the safety/tolerability and preliminary antitumor activity of HB-201 and HB-202, an arenavirus-based cancer immunotherapy, in patients with HPV16+ cancers., Alan L. Ho, Marshall R. Posner, and Rom Leidner

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Intravenous Cetirizine vs Intravenous Diphenhydramine for the Prevention of Hypersensitivity Infusion Reactions: Results of an Exploratory Phase 2 Study., Jarrod P Holmes, Julio A Peguero, R Campbell Garland, Janine North, Stacia Young, Lonnie D Brent, and Nancy Joseph-Ridge

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Intravenous Cetirizine vs Intravenous Diphenhydramine for the Prevention of Hypersensitivity Infusion Reactions: Results of an Exploratory Phase 2 Study., Jarrod P Holmes, Julio A Peguero, R Campbell Garland, Janine North, Stacia Young, Lonnie D Brent, and Nancy Joseph-Ridge

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Mogamulizumab in Combination with Nivolumab in a Phase I/II Study of Patients with Locally Advanced or Metastatic Solid Tumors., David S Hong, Olivier Rixe, Vi K Chiu, Patrick M Forde, Tomislav Dragovich, Yanyan Lou, Asha Nayak-Kapoor, Rom Leidner, James N Atkins, Agron Collaku, Floyd E Fox, Margaret A Marshall, and Anthony J Olszanski

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EpiMap: Fine-tuning integrative epigenomics maps to understand complex human regulatory genomic circuitry., Dave S B Hoon, Negin Rahimzadeh, and Matias A Bustos

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Reconciling Non-Genetic Plasticity with Somatic Evolution in Cancer., Sui Huang

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Integrated genetic and metabolic landscapes predict vulnerabilities of temozolomide resistant glioblastoma cells., Selva Rupa Christinal Immanuel, Avinash D Ghanate, Dharmeshkumar S Parmar, Ritu Yadav, Riya Uthup, Venkateswarlu Panchagnula, and Anu Raghunathan

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Intrapelvic Pseudotumor Presenting with Deep Vein Thrombosis After Hip Replacement with Metal-on-Metal Bearing Surface Implant: A Case Report., Sahir Jabbouri, Gina Lee, Thomas Stonecipher, and Michal Nawalany

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In Their Voice: What Do Caregivers of Patients with Cancer Need?, Ahlam Jadalla

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The Effects of Cardiorespiratory and Motor Skill Fitness on Intrinsic Functional Connectivity of Neural Networks in Individuals with Parkinson's Disease., Behnaz Jarrahi, Sarah C McEwen, Daniel P Holschneider, Dawn M Schiehser, Andrew J Petkus, Megan E Gomez, Jack D Van Horn, Vincent Filoteo, Michael W Jakowec, and Giselle M Petzinger

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Initial results of a first-in-human, dose escalation study of a cell-based vaccine in HLA A*02+ patients (pts) with recurrent, locally advanced or metastatic HPV16+ solid tumors: SQZ-PBMC-HPV-101., Antonio Jimeno, Joaquina C. Baranda, Matthew H Taylor, and See all authors in comments

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Phase I, First-in-Human Study of the Probody Therapeutic CX-2029 in Adults with Advanced Solid Tumor Malignancies., Melissa Johnson, Anthony El-Khoueiry, Navid Hafez, Nehal Lakhani, Hirva Mamdani, Jordi Rodon, Rachel E Sanborn, Javier Garcia-Corbacho, Valentina Boni, Mark Stroh, Alison L Hannah, Song Wang, Henry Castro, and Alexander Spira

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Effect of prior therapy on tumor mutational burden in NSCLC., Sushma Jonna, Ari Vanderwalde, Jorge Nieva, Kelsey Anne Poorman, Michelle Saul, Xinyu von Buttlar, John Y Hu, and Stephen V Liu

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Toxicity After Stereotactic Body Radiation Therapy for Prostate Cancer in Patients With Inflammatory Bowel Disease: A Multi-institutional Matched Case-Control Series., Jesus E Juarez, Tahmineh Romero, Constantine A Mantz, Abigail Pepin, Nima Aghdam, Simeng Suy, Michael L Steinberg, Rebecca G Levin-Epstein, Nicholas G Nickols, Irving D Kaplan, Robert M Meier, Huong T Pham, Patrick W Linson, Robert L Hong, Mark K Buyyounouski, Hilary P Bagshaw, Donald B Fuller, Alan J Katz, Andrew Loblaw, Sean P Collins, and Amar U Kishan

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Microfluidic Single-Cell Proteomics Assay Chip: Lung Cancer Cell Line Case Study., Yugyung Jung, Minkook Son, Yu Ri Nam, Jongchan Choi, James R Heath, and Sung Yang

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Results of a randomized phase 3 study of oral sapacitabine in elderly patients with newly diagnosed acute myeloid leukemia (SEAMLESS)., Hagop M Kantarjian, Kebede H Begna, Jessica K Altman, Stuart L Goldberg, Mikkael A Sekeres, Stephen A Strickland, Martha L Arellano, David F Claxton, Maria R Baer, Marc Gautier, Ellin Berman, Karen Seiter, Scott R Solomon, Gary J Schiller, Selina M Luger, Aleksandra Butrym, Gianluca Gaidano, Xavier G Thomas, Pau Montesinos, David A Rizzieri, Donald Quick, Parameswaran Venugopal, Rakesh Gaur, Lori J Maness, Tapan M Kadia, Farhad Ravandi, Marc E Buyse, and Judy H Chiao

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Multi-omic Profiling of Simultaneous Ductal Carcinoma In Situ and Invasive Breast Cancer, Henry G. Kaplan, Anna B. Berry, Alexa Dowdell, and Brian D. Piening

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Treatment of PCM1-JAK2 fusion tyrosine kinase gene-related acute lymphoblastic leukemia with stem cell transplantation, Henry G Kaplan, Carlo Bifulco, Ruyun Jin, James M Scanlan, and David Colvin

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Risk Factors for Intravesical Recurrence after Minimally Invasive Nephroureterectomy for Upper Tract Urothelial Cancer (ROBUUST Collaboration)., Andrew B Katims, Rollin Say, Ithaar Derweesh, Robert Uzzo, Andrea Minervini, Zhenjie Wu, Firas Abdollah, Chandru Sundaram, Matteo Ferro, Koon Rha, Alex Mottrie, Giuseppe Rosiello, Giuseppe Simone, Daniel D Eun, Adam Reese, Laura C Kidd, James R Porter, Amit Satish Bhattu, Mark L Gonzalgo, Vitaly Margulis, Jamil Marcus, Alyssa Danno, Margaret Meagher, Riccardo Tellini, Andrea Mari, Alessandro Veccia, Alireza Ghoreifi, Riccardo Autorino, Hooman Djaladat, and Reza Mehrazin

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Doxorubicin in combination with cisplatin, 5-flourouracil, and vincristine is feasible and effective in unresectable hepatoblastoma: A Children's Oncology Group study., Howard M Katzenstein, Marcio H Malogolowkin, Mark D Krailo, Jin Piao, Alexander J Towbin, M Beth McCarville, Gregory M Tiao, Stephen P Dunn, Max R Langham, Eugene D McGahren, Milton J Finegold, Sarangarajan Ranganathan, Christopher B Weldon, Patrick A Thompson, Angela Trobaugh-Lotrario, Allison F O'Neill, Wayne L Furman, Nadia Chung, Jessica Randazzo, Carlos Rodriguez-Galindo, and Rebecka L Meyers

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Human Breast Extracellular Matrix Microstructures and Protein Hydrogel 3D Cultures of Mammary Epithelial Cells., Chandler R Keller, Yang Hu, Kelsey F Ruud, Anika E VanDeen, Steve R Martinez, Barry T Kahn, Zhiwu Zhang, Roland K Chen, and Weimin Li

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Treatment dependent improvements in survival of stage 2/3 rectal cancer patients treated with trimodality therapy between 2006-2016, an NCDB analysis., Hagen F Kennecke, Henry T. Bahnson, and See list of authors in comments

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CCTG CO.28 primary endpoint analysis: Neoadjuvant chemotherapy, excision and observation for early rectal cancer, the NEO trial., Hagen F Kennecke, Carl J. Brown, and See full list of authors in comments

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Mesenchymal stem cells in the treatment of severe COVID-19., Santosh Kesari, Gregory C Kasper, Lev Verkh, Terese C Hammond, Marla L Matal, Jay W Hammerling, Nikolai Tankovich, Adrianus P Lim, Kevin H Zhao, Tiffany Juarez, Roberta E Redfern, Jaya M Gill, Natsuko Nomura, Audrey Hiemer, Annie Heng, and Jessica Shoemaker

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Response to: Is there any association between a delay in surgery and nodal positivity in the ER-negative Her2 negative breast cancer subgroups?, Adam Khader and Trevan Fischer