Submissions from 2020
799 Durable responses and immune activation with intratumoral electroporation of pIL-12 plus pembrolizumab in actively progressing anti-PD-1 refractory advanced melanoma: KEYNOTE 695 interim data, Pablo Fernandez-Penas, Matteo Carlino, Katy Tsai, Victoria Atkinson, Monater Shaheen, Sajeve Thomas, Catalin Mihalcioiu, Tom Van Hagen, Rachel Roberts-Thomson, Andrew Haydon, Andrew Mant, Marcus Butler, Gregory Daniels, Elizabeth Buchbinder, John Hyngstrom, Mecker Moller, Igor Puzanov, C Lance Cowey, Eric Whitman, Carmen Ballesteros-Merino, Shawn M. Jensen, Bernard A Fox, Emmett Schmidt, Clemens Krepler, Scott Diede, Erica Browning, Reneta Hermiz, Lauren Svenson, Jon Salazar, Jack Lee, Christopher Baker, Donna Bannavong, Jendy Sell, Kellie Malloy Foerter, David Canton, Sandra Aung, Christopher Twitty, Alain Algazi, and Adil Daud
A novel surgeon credentialing and quality assurance process using transoral surgery for oropharyngeal cancer in ECOG-ACRIN Cancer Research Group Trial E3311., Robert L Ferris, Yael Flamand, F Christopher Holsinger, Gregory S Weinstein, Harry Quon, Ranee Mehra, Joaquin J Garcia, Michael L Hinni, Neil D Gross, Erich M Sturgis, Umamaheswar Duvvuri, Eduardo Méndez, John A Ridge, J Scott Magnuson, Kerry A Higgins, Mihir R Patel, Russel B Smith, Daniel W Karakla, Michael E Kupferman, James P Malone, Benjamin L Judson, Jeremy Richmon, Jay O Boyle, Rodrigo Bayon, Bert W O'Malley, Enver Ozer, Giovana R Thomas, Wayne M Koch, Richard Bryan Bell, Nabil F Saba, Shuli Li, Elin R Sigurdson, and Barbara Burtness
Transoral robotic surgical resection followed by randomization to low- or standard-dose IMRT in resectable p16+ locally advanced oropharynx cancer: A trial of the ECOG-ACRIN Cancer Research Group (E3311)., Robert L. Ferris, Yael Flamand, Gregory S. Weinstein, Shuli Li, Harry Quon, Ranee Mehra, Joaquin J. Garcia, Christine H. Chung, Maura L. Gillison, Umamaheswar Duvvuri, Bert W. O'Malley, Enver Ozer, Giovanna R. Thomas, Wayne Koch, Michael Elliot Kupferman, Richard Bryan Bell, Nabil F. Saba, Miriam Lango, Eduardo Mendez, and Barbara Burtness
The Efficacy of Passive Valve Antimicrobial Swab Caps Against Existing Clabsi Prevention Bundle in an Adult Hematology Inpatient Population: A Quality Improvement Initiative, Joseph F. Ferry, Neil Bailey, Vanessa Dunleavy, Joanna Fesler, Judson Hall, Sonia Glennie, William Bensinger, Raya Mawad, Krish Patel, Daniel N Egan, John M Pagel, and Livia Hegerova
Resolution of eicosanoid/cytokine storm prevents carcinogen and inflammation-initiated hepatocellular cancer progression., Anna Fishbein, Weicang Wang, Haixia Yang, Jun Yang, Victoria M Hallisey, Jianjun Deng, Sanne M L Verheul, Sung Hee Hwang, Allison Gartung, Yuxin Wang, Diane R Bielenberg, Sui Huang, Mark W Kieran, Bruce D Hammock, and Dipak Panigrahy
Cetuximab in Patients with Breast Cancer, Non-Small Cell Lung Cancer, and Ovarian Cancer Without KRAS, NRAS, or BRAF Mutations: Results from the Targeted Agent and Profiling Utilization Registry (TAPUR) Study., Julie G Fisher, David Tait, Elizabeth Garrett-Mayer, Susan Halabi, Pam K Mangat, Julian C Schink, Ricardo H Alvarez, Dan Veljovich, Timothy L Cannon, Pamela A Crilley, Theodore Pollock, Carmen J Calfa, Tareq Al Baghdadi, Ramya Thota, Nicole Fleming, Jared A Cotta, Andrew L Rygiel, Sasha L Warren, and Richard L Schilsky
Colon and Rectal Surgery Robotic Training Programs: An Evaluation of Gender Disparities., Katherine E Foley, Kevin M Izquierdo, Madrigal G von Muchow, Amir Bastawrous, Robert K Cleary, and Mark K Soliman
A profile on the FoundationFocus CDxBRCA tests., Lindsey Ford, Juliet E Wolford, Sandra Brown, and Leslie M Randall
The combination of ibrutinib and rituximab demonstrates activity in first-line follicular lymphoma., Nathan H Fowler, Loretta Nastoupil, Sven De Vos, Mark Knapp, Ian W Flinn, Robert Chen, Ranjana H Advani, Sumeet Bhatia, Peter Martin, Raul Mena, Richard Eric Davis, Sattva S Neelapu, Karl Eckert, Jerry Ping, Melannie Co, Darrin M Beaupre, Jutta K Neuenburg, and M Lia Palomba
Cancer vaccines yesterday, today, and tomorrow: Cinderella no more?, Bernard A Fox
Immunotherapy-induced anti-cancer responses, Bernard A Fox
Immunotherapy-Induced Anti-Cancer Responses, Bernard A Fox
443 An immunotherapy trio in advanced HNSCC for coordinated B and T cell antigen response, Bernard A Fox, Tarsem Moudgil, Traci Hilton, Noriko Iwamoto, Christopher Paustian, Adi Mehta, Fridtjof Lund-Johansen, Rachel E Sanborn, Richard Bryan Bell, Madeleine Laws, Glenna McDonnell, Yoshinobu Koguchi, Carlo Bifulco, Brian D. Piening, Carmen Ballesteros-Merino, Shawn M. Jensen, Takashi Shimada, Hong-Ming Hu, Walter Urba, Rom Leidner, and Marcus Couey
443 An immunotherapy trio in advanced HNSCC for coordinated B and T cell antigen response, Bernard A Fox, Tarsem Moudgil, Traci Hilton, Noriko Iwamoto, Christopher Paustian, Adi Mehta, Fridtjof Lund-Johansen, Rachel E Sanborn, Richard Bryan Bell, Madeline Laws, Glenna McDonnell, Yoshinobu Koguchi, Carlo Bifulco, Brian D. Piening, Carmen Ballesteros-Merino, Shawn M. Jensen, Takashi Shimada, Hong-Ming Hu, Walter Urba, Rom Leidner, and Marcus Couey
Immunoscore as a parameter predicting time to recurrence and disease-free survival in T4N0 stage II colon cancer patients., Jerome Galon, Fabienne Hermitte, Bernhard Mlecnik, Alessandro Lugli, Carlo Bifulco, Iris D. Nagtegaal, Arndt Hartmann, Florence Marliot, Marc Van Den Eynde, Michael H.A. Roehrl, Pamela S. Ohashi, Eva Zavadova, Toshihiko Torigoe, Prabhudas S. Patel, Yili Wang, Yutaka Kawakami, Francesco Marincola, Paolo Antonio Ascierto, Bernard A Fox, and Franck Pages
Prognostic Impact and Utility of Immunoprofiling in the Selection of Patients with Colorectal Peritoneal Carcinomatosis for Cytoreductive Surgery (CRS) and Heated Intraperitoneal Chemotherapy (HIPEC)., Mary Garland-Kledzik, Abhineet Uppal, Yalda Naeini, Stacey L Stern, Richard Erali, Anthony J Scholer, Adam Khader, Juan A Santamaria-Barria, Kathleen Cummins-Perry, Yi Zhou, Konstantinos I Votanopoulos, Perry Shen, Edward A Levine, and Anton J Bilchik
Prior tonsillectomy is associated with an increased risk of esophageal adenocarcinoma., Katherine S Garman, Teminioluwa A Ajayi, Harold J Boutte, Shih-Ting Chiu, Richard J von Furstenberg, Benjamin R Lloyd, Cecelia Zhang, Mark W Onaitis, Shein-Chung Chow, and Shannon J McCall
1074TiP SGNTGT-001: A phase I study of SGN-TGT, an effector-function enhanced monoclonal antibody (mAb), in advanced malignancies, E Garralda, Rachel E Sanborn, AR Minchom, D Davar, G Curigliano, V Ribrag, A Mehta, F Foss, P Garfin, and S Ansell
Management of early hepatocellular carcinoma: results of the Delphi consensus process of the Americas Hepato-Pancreato-Biliary Association., Sepideh Gholami, Lauren M Perry, Jason W Denbo, Kenneth Chavin, Philippa H Newell, Quan Ly, Charles St Hill, Gareth Morris-Stiff, Jonathan Kessler, Timothy L Frankel, Neehar D Parikh, Prejesh Philips, George Salti, Toms Augustin, Federico Aucejo, Meelie Debroy, Natalie Coburn, and Susanne G Warner
Part One: 2. Screening and Early Detection, Jaya M. Gill Ed.
Disparities in the Occurrence of Late Effects following Treatment among Adolescent and Young Adult Melanoma Survivors., Alicia A Gingrich, Candice A M Sauder, Melanie Goldfarb, Qian Li, Ted Wun, and Theresa H M Keegan
Safety and Clinical Activity of MEDI0562, a Humanized OX40 Agonist Monoclonal Antibody, in Adult Patients with Advanced Solid Tumors., Bonnie S Glisson, Rom Leidner, Robert L Ferris, John Powderly, Naiyer A Rizvi, Bhumsuk Keam, Reva Schneider, Sanjay Goel, James P Ohr, Jennifer Burton, Yanan Zheng, Steven Eck, Matthew Gribbin, Katie Streicher, Danielle M Townsley, and Sandip Pravin Patel
Outcomes of Treatment with the Chimeric Antigen Receptor (CAR) T Cell Therapy Lisocabtagene Maraleucel (liso-cel) in the Nonuniversity Setting: Initial Results from the Outreach Study, John E Godwin, Cesar O. Freytes, Michael Maris, Don A. Stevens, Daanish Hoda, Bassam Mattar, Juan C. Varela, Mohamad Cherry, James Essell, Jay Courtright, Suzanne R. Fanning, Habte A. Yimer, Nikolaus S. Trede, Marina Youssef, James Lymp, and Carlos Bachier
Blood test shows high accuracy in detecting stage I non-small cell lung cancer., Cherylle Goebel, Christopher L Louden, Robert McKenna, Osita Onugha, Andrew Wachtel, and Thomas Long
Recent advances in the understanding and management of primary hyperparathyroidism., Melanie Goldfarb and Frederick R Singer
Safety and tolerability of MEDI0562 in combination with durvalumab or tremelimumab in patients with advanced solid tumors., Jonathan Wade Goldman, Sarina Anne Piha-Paul, Brendan Curti, Katrina Pedersen, Todd Michael Bauer, Stefanie L. Groenland, Richard D. Carvajal, Vaishali Chhaya, Scott A. Hammond, Katie Streicher, Danielle Michelle Townsley, Young Kwang Chae, Jens Voortman, Aurelien Marabelle, and John D. Powderly
Safety and tolerability of MEDI0562 in combination with durvalumab or tremelimumab in patients with advanced solid tumors., Jonathan Wade Goldman, Sarina Anne Piha-Paul, Brendan Curti, Katrina Pedersen, Todd Michael Bauer, Stefanie L. Groenland, Richard D. Carvajal, Vaishali Chhaya, Scott A. Hammond, Katie Streicher, Danielle Michelle Townsley, Young Kwang Chae, Jens Voortman, Aurelien Marabelle, and John D. Powderly
CT191 - Interim results from CLASSICAL-Lung, phase 1b/2 study of pepinemab (VX15/2503) in combination with avelumab in advanced NSCLC, Jonathan W. Goldman, Terrence L. Fisher, Elizabeth Evans, John E. Leonard, Desa Rae Pastore, Crystal Mallow, Ernest Smith, Andreas Schroder, Kevin Chin, Michael Shafique, Thaddeus Beck, Megan A. Baumgart, Ramaswamy Govindan, Nashat Gabrail, Rachel E Sanborn, Alexander Spira, Nagashree Seetharamu, Yanyan Lou, Aaron S. Mansfield, and Maurice Zauderer
Abstract CT191: Interim results from CLASSICAL-Lung, phase 1b/2 study of pepinemab (VX15/2503) in combination with avelumab in advanced NSCLC, Jonathan W. Goldman, Terrence L. Fisher, Elizabeth Evans, John E. Leonard, Desa Rae Pastore, Crystal Mallow, Ernest Smith, Andreas Schroeder, Kevin Chin, Michael Shafique, Thaddeaus Beck, Megan A. Baumgart, Ramaswamy Govindan, Nashat Gabrail, Rachel E Sanborn, Alexander I. Spira, Nagashree Seetharamu, Yanyan Lou, Aaron S. Mansfield, and Maurice Zauderer
Using Preclinical Data to Design Combination Clinical Trials of Radiation Therapy and Immunotherapy., Michael J. Gough, Shay Sharon, Marka R Crittenden, and Kristina H Young
Using Preclinical Data to Design Combination Clinical Trials of Radiation Therapy and Immunotherapy., Michael J. Gough, Shay Sharon, Marka R Crittenden, and Kristina H Young
Prospective Study of Use of Edmonton Symptom Assessment Scale Versus Routine Symptom Management During Weekly Radiation Treatment Visits., Uma D Goyal, Kristen Riegert, Rajayogesh Davuluri, Shawn Ong, Sun K Yi, Shona T Dougherty, and Charles C Hsu
Pembrolizumab immunotherapy for relapsed CNS Lymphoma., Jerome J Graber, Benjamin Plato, Raya Mawad, and Daniel J Moore
A phase II single-arm study of pembrolizumab with enzalutamide in men with metastatic castration-resistant prostate cancer progressing on enzalutamide alone., Julie N Graff, Tomasz M Beer, Joshi J Alumkal, Rachel E Slottke, William L. Redmond, George V Thomas, Reid F Thompson, Mary A Wood, Yoshinobu Koguchi, Yiyi Chen, Emile Latour, Raymond C Bergan, Charles G Drake, and Amy E Moran
Conserved Interferon-γ Signaling Drives Clinical Response to Immune Checkpoint Blockade Therapy in Melanoma., Catherine S Grasso, Jennifer Tsoi, Mykola Onyshchenko, Gabriel Abril-Rodriguez, Petra Ross-Macdonald, Megan Wind-Rotolo, Ameya Champhekar, Egmidio Medina, Davis Y Torrejon, Daniel Sanghoon Shin, Phuong Tran, Yeon Joo Kim, Cristina Puig-Saus, Katie Campbell, Agustin Vega-Crespo, Michael Quist, Christophe Martignier, Jason J Luke, Jedd D Wolchok, Douglas B Johnson, Bartosz Chmielowski, F Stephen Hodi, Shailender Bhatia, William Sharfman, Walter Urba, Craig L Slingluff, Adi Diab, John B A G Haanen, Salvador Martin Algarra, Drew M Pardoll, Valsamo Anagnostou, Suzanne L Topalian, Victor E Velculescu, Daniel E Speiser, Anusha Kalbasi, and Antoni Ribas
Germinal centers in tertiary lymphoid structures distinguish long-term pancreatic cancer survivors associated with neoantigen expression and immune memory, Andrew J Gunderson
TGFβ suppresses CD8+ T cell expression of CXCR3 and tumor trafficking., Andrew J Gunderson, Tomoko Yamazaki, Kayla McCarty, Nathaniel E Fox, Michaela Phillips, Alejandro F Alice, Tiffany Blair, Mark Whiteford, David O'Brien, Rehan Ahmad, Maria X Kiely, Amanda Hayman, Todd Crocenzi, Michael J. Gough, Marka R. Crittenden, and Kristina H Young
Novel application of vinylpolysiloxane hearing aid impression mold as patient-specific bolus for head and neck cancer radiotherapy., Anne Elizabeth Gunter, John Burgoyne, Min Park, Namou Kim, Daliang Cao, and Vivek Mehta
Initial and Consolidation Therapy for Younger Patients with Mantle Cell Lymphoma., Daniel Guy and Brad S Kahl
Surveillance for second breast cancer events in women with a personal history of breast cancer using breast MRI: a systematic review and meta-analysis., Cameron B Haas, Larissa Nekhlyudov, Janie M Lee, Sara H Javid, Mary Bush, Dianne Johnson, Timothy Gleason, Cary Kaufman, Jennifer Specht, Sean Stitham, and Karen J Wernli
The importance of age as prognostic factor for the outcome of patients with hepatoblastoma: Analysis from the Children's Hepatic tumors International Collaboration (CHIC) database., Beate Haeberle, Arun Rangaswami, Mark Krailo, Piotr Czauderna, Eiso Hiyama, Rudolf Maibach, Dolores Lopez-Terrada, Daniel C Aronson, Rita Alaggio, Marc Ansari, Marcio H Malogolowkin, Giorgio Perilongo, Allison F O'Neill, Angela Trobaugh-Lotrario, Kenichiro Watanabe, Irene Schmid, Dietrich von Schweinitz, Sarangarajan Ranganathan, Kenichi Yoshimura, Tomoro Hishiki, Yukichi Tanaka, Jin Piao, Yurong Feng, Eugenia Rinaldi, Davide Saraceno, Marisa Derosa, and Rebecka L Meyers
Perianal basal cell carcinoma: a common cancer in an uncommon location., Ed Hagen, Nathan Hite, John A Griffin, and Rodney Kratz
Laparoscopic Transhiatal Esophagectomy for Invasive Esophageal Adenocarcinoma., Kelly R Haisley, Walaa F Abdelmoaty, and Christy M Dunst
Results of Lung Cancer Screening in the Community., John R Handy, Michael Skokan, Erika Rauch, Steven Zinck, Rachel E Sanborn, Svetlana Kotova, and Mansen Wang
Results of Lung Cancer Screening in the Community., John R Handy, Michael Skokan, Erika Rauch, Steven Zinck, Rachel E Sanborn, Svetlana Kotova, and Mansen Wang
How we treat left-sided vs right-sided colon cancer., Diana L Hanna and Heinz-Josef Lenz
INDUCE-3: A randomized, double-blind study of GSK3359609 (GSK609), an inducible T-cell co-stimulatory (ICOS) agonist antibody, plus pembrolizumab (PE) versus placebo (PL) plus PE for first-line treatment of PD-L1-positive recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC)., Aaron Richard Hansen, Thomas Stanton, Min Hee Hong, Ezra EW Cohen, Hisham Mohamed Mehanna, Michael Jon Chisamore, David Turner, Sapna Yadavilli, Kelly Bell, Carlos Baccan, Rosalida Leone, Helen Chen, Helen Zhou, Catherine Elizabeth Ellis, Marc S. Ballas, Axel Hoos, and Danny Rischin
Three-Dimensional Computer-Assisted Surgical Planning, Manufacturing, and Intraoperative Navigation in Oncologic Surgery., Phillip Harrison, Ashish Patel, Allen C Cheng, and Richard Bryan Bell
The Effects of Music Medicine on Reducing Distress, Anxiety, and Pain During Bone Marrow Biopsy Procedures, Betsy Hartman, Sharon Mast, and Judy Delismon
An atypical case of necrotizing fasciitis secondary to perforated cecal cancer., Laura S Heidelberg, Erica Pettke, Teresa E Wagner, and Lauren Angotti
Simultaneously spatial and temporal Higher-Order Total Variations for noise suppression and motion reduction in DCE and IVIM., Renjie He, Yao Ding, Abdallah S R Mohamed, Sweet Ping Ng, Rachel B Ger, Hesham Elhalawani, Baher A Elgohari, Kristina H Young, Katherine A Hutcheson, Clifton D Fuller, and Stephen Y Lai
Thrombospondin-1 counteracts the p97 inhibitor CB-5083 in colon carcinoma cells., Nam-Gu Her, Santosh Kesari, and Elmar Nurmemmedov
Stapled Diaphragmatic Plication: Is It Better Than Suture Plication?, Terra M Hill and Osita Onugha
Allogeneic autophagosome-enriched composition for the treatment of disease, Traci Hilton, Sandra Aung, Rieneke van de Ven, Christopher Paustian, Tarsem Moudgil, Christopher Dubay, Christopher Twitty, Hong-Ming Hu, and Bernard A Fox
Allogeneic autophagosome-enriched composition for the treatment of disease, Traci Hilton, Sandra Aung, Rieneke van de Ven, Christopher Paustian, Tarsem Moudgil, Christopher Dubay, Christopher Twitty, Hong-Ming Hu, and Bernard A Fox
Allogeneic autophagosome-enriched composition for the treatment of disease, Traci Hilton, Sandra Aung, Rieneke van de Ven, Christopher Paustian, Tarsem Moudgil, Christopher Dubay, Christopher Twitty, Hong-Ming Hu, and Bernard A Fox
Allogeneic autophagosome-enriched composition for the treatment of disease, Traci Hilton, Sandra Aung, Rieneke van de Ven, Christopher Paustian, Tarsem Moudgil, Christopher Dubay, Christopher Twitty, Hong-Ming Hu, and Bernard A Fox
Simultaneous Isolation of Circulating Nucleic Acids and EV-Associated Protein Biomarkers From Unprocessed Plasma Using an AC Electrokinetics-Based Platform., Juan Pablo Hinestrosa, David J Searson, Jean M Lewis, Alfred Kinana, Orlando Perrera, Irina Dobrovolskaia, Kevin Tran, Robert Turner, Heath I Balcer, Iryna Clark, David Bodkin, Dave Hoon, and Rajaram Krishnan
Breast cancer care during a pandemic: an opportune time for cryoablation?, Dennis R Holmes
Patients With Natural Killer (NK) Cell Chronic Active Epstein-Barr Virus Have Immature NK Cells and Hyperactivation of PI3K/Akt/mTOR and STAT1 Pathways., Matthew K Howe, Kennichi Dowdell, Hye Sun Kuehn, Qingxue Li, Geoffrey T Hart, Doreen Garabedian, Kelly Liepshutz, Amy P Hsu, Hua Su, Julie E Niemela, Jennifer L Stoddard, Gulbu Uzel, Evan Shereck, Laura Schulz, Tatyana Feldman, Sergio D Rosenzweig, Eric O Long, Lesia Dropulic, and Jeffrey I Cohen
Complete response with talimogene laherparepvec in recurrent melanoma of the ear: A case report., Ashley C Hsu, Niels C Kokot, Burton L Eisenberg, and Jacob S Thomas
SITC cancer immunotherapy resource document: a compass in the land of biomarker discovery., Siwen Hu-Lieskovan, Srabani Bhaumik, Kavita Dhodapkar, Jean-Charles J B Grivel, Sumati Gupta, Brent A Hanks, Sylvia Janetzki, Thomas O Kleen, Yoshinobu Koguchi, Amanda W Lund, Cristina Maccalli, Yolanda D Mahnke, Ruslan D Novosiadly, Senthamil R Selvan, Tasha Sims, Yingdong Zhao, and Holden T Maecker
Cumulative suppressive index as a predictor of relapse free survival and overall survival in Human Papilloma Virus-negative oral squamous cell carcinomas with negative resection margins., Lauren Hum, Daniel Bethmann, Zipei Feng, Shu-Ching Chang, Alexander Eckert, Carmen Ballesteros-Merino, Claudia Keschke, Matthias Kappler, Carlo Bifulco, Claudia Wickenhauser, Barbara Seliger, Bernard A Fox, and Richard Bryan Bell
Survival with Olaparib in Metastatic Castration-Resistant Prostate Cancer., Maha Hussain, Joaquin Mateo, Karim Fizazi, Fred Saad, Neal Shore, Shahneen Sandhu, Kim N Chi, Oliver Sartor, Neeraj Agarwal, David Olmos, Antoine Thiery-Vuillemin, Przemyslaw Twardowski, Guilhem Roubaud, Mustafa Özgüroğlu, Jinyu Kang, Joseph Burgents, Christopher Gresty, Claire Corcoran, Carrie A Adelman, and Johann de Bono
Building a circular RNA centered gene regulation network associated with cervical squamous cell carcinoma., Wei Hu, Qingqing Li, Xiaoyi He, Ming Gao, Zhanfu Zheng, Yuanlin Ding, Kai Wang, and Yuqing He
Molecular profiling of melanoma brain metastases compared to primary cutaneous melanoma and to extracranial metastases., Gino K In, Kelsey Poorman, Michelle Saul, Steven O'Day, Jeffrey M Farma, Anthony J Olszanski, Michael S Gordon, Jacob S Thomas, Burton Eisenberg, Lawrence Flaherty, Amy Weise, Steven Daveluy, Geoffrey Gibney, Michael B Atkins, and Ari Vanderwalde
Association of Event-Free and Distant Recurrence-Free Survival With Individual-Level Pathologic Complete Response in Neoadjuvant Treatment of Stages 2 and 3 Breast Cancer: Three-Year Follow-up Analysis for the I-SPY2 Adaptively Randomized Clinical Trial., I-SPY2 Trial Consortium, Douglas Yee, Angela M DeMichele, Christina Yau, Claudine Isaacs, W Fraser Symmans, Kathy S Albain, Yunn-Yi Chen, Gregor Krings, Shi Wei, Shuko Harada, Brian Datnow, Oluwole Fadare, Molly Klein, Stefan Pambuccian, Beiyun Chen, Kathi Adamson, Sharon Sams, Paulette Mhawech-Fauceglia, Anthony Magliocco, Mike Feldman, Mara Rendi, Husain Sattar, Jay Zeck, Idris T Ocal, Ossama Tawfik, Lauren Grasso LeBeau, Sunati Sahoo, Tuyethoa Vinh, A Jo Chien, Andres Forero-Torres, Erica Stringer-Reasor, Anne M Wallace, Lajos Pusztai, Judy C Boughey, Erin D Ellis, Anthony D Elias, Janice Lu, Julie E Lang, Hyo S Han, Amy S Clark, Rita Nanda, Donald W Northfelt, Qamar J Khan, Rebecca K Viscusi, David M Euhus, Kirsten K Edmiston, Stephen Y Chui, Kathleen Kemmer, John W Park, Minetta C Liu, Olufunmilayo Olopade, Brian Leyland-Jones, Debasish Tripathy, Stacy L Moulder, Hope S Rugo, Richard Schwab, Shelly Lo, Teresa Helsten, Heather Beckwith, Patricia Haugen, Nola M Hylton, Laura J Van't Veer, Jane Perlmutter, Michelle E Melisko, Amy Wilson, Garry Peterson, Adam L Asare, Meredith B Buxton, Melissa Paoloni, Julia L Clennell, Gillian L Hirst, Ruby Singhrao, Katherine Steeg, Jeffrey B Matthews, Smita M Asare, Ashish Sanil, Scott M Berry, Laura J Esserman, and Donald A Berry
Determinant factors on differences in survival for gastric cancer between the US and Japan using nationwide databases., Yuri Ito, Isao Miyashiro, Takashi Ishikawa, Kohei Akazawa, Keisuke Fukui, Hitoshi Katai, Souya Nunobe, Ichiro Oda, Yoh Isobe, Shunichi Tsujitani, Hiroyuki Ono, Satoshi Tanabe, Takeo Fukagawa, Satoshi Suzuki, Yoshihiro Kakeji, Mitsuru Sasako, Anton J Bilchik, and Manabu Fujita
The melanoma brain metastatic microenvironment: aldolase C partakes in shaping the malignant phenotype of melanoma cells - a case of inter-tumor heterogeneity., Sivan Izraely, Shlomit Ben-Menachem, Orit Sagi-Assif, Tsipi Meshel, Sapir Malka, Alona Telerman, Matias A Bustos, Romela Irene Ramos, Metsada Pasmanik-Chor, Dave Hoon, and Isaac P Witz
Modulation of Immune Checkpoints by Chemotherapy in Human Colorectal Liver Metastases., Neda Jabbari, Heidi L Kenerson, Christopher Lausted, Xiaowei Yan, Changting Meng, Kevin M Sullivan, Priyanka Baloni, Dani E Bergey, Venu G Pillarisetty, Leroy Hood, Raymond S Yeung, and Qiang Tian
Staging System for Neuroendocrine Tumors of the Lung Needs to Incorporate Histologic Grade., Anee Sophia Jackson, Adam Rosenthal, Maria Cattoni, Adam J Bograd, Alexander S Farivar, Ralph W Aye, Eric Vallières, and Brian Louie
Primary surgical management of complicated pleural space infections has superior outcomes when compared to intra-pleural fibrinolytic therapy, AS Jackson, CL Wilshire, SC Chang, LC Horslen, JR Rayburn, CC Fuller, AS Farivar, AJ Bograd, RW Aye, BE Louie, E Vallières, CR Gilbert, and JA Gorden
The role of antimicrobial prophylaxis in patients with head and neck cancer undergoing chemoradiation., Alina T Jaeger, James E Connelly, Ruyun Jin, Samuel N Jacobson, and Rom Leidner
The effect of radiation therapy on post-prostatectomy urinary function., David Jenkins, Gregory P Swanson, Sameer G Jhavar, Kristofer R Wagner, Chul S Ha, and Wencong Chen
480 Preliminary evaluation of a novel coronavirus vaccine (CORVax) using electroporation of plasmid DNA encoding a stabilized prefusion SARS-CoV-2 spike protein alone or with transfection of plasmid IL-12, Shawn M. Jensen, Christopher Twitty, Christopher Paustian, Madelein Laws, Glenna McDonnell, Keith W Wegman, Tarsem Moudgil, Michael E Afentoulis, Mia Han, Kellie Malloy Foerter, David Canton, Jack Lee, Bianca Nguyen, John Rodriguez, Kim Jaffe, Brian D. Piening, Carlo Bifulco, Daniel O'Connor, Walter Urba, Rom Leidner, Traci Hilton, Hong-Ming Hu, and Bernard A Fox
480 Preliminary evaluation of a novel coronavirus vaccine (CORVax) using electroporation of plasmid DNA encoding a stabilized prefusion SARS-CoV-2 spike protein alone or with transfection of plasmid IL-12, Shawn M. Jensen, Christopher Twitty, Christopher Paustian, Madelein Laws, Glenna McDonnell, Keith W Wegmann, Tarsem Moudgil, Michael E Afentoulis, Mia Han, Kellie Malloy Foerter, David Canton, Jack Lee, Biance Nguyen, John Rodriguez, Kim Jaffe, Brian D. Piening, Carlo Bifulco, Daniel O'Connor, Walter Urba, Rom Leidner, Traci Hilton, Hong-Ming Hu, and Bernard A Fox
The relationship between body-mass index and overall survival in non-small cell lung cancer by sex, smoking status, and race: A pooled analysis of 20,937 International lung Cancer consortium (ILCCO) patients., Mei Jiang, Aline F Fares, Daniel Shepshelovich, Ping Yang, David Christiani, Jie Zhang, Kouya Shiraishi, Brid M Ryan, Chu Chen, Ann G Schwartz, Adonina Tardon, Sanjay Shete, Matthew B Schabath, M Dawn Teare, Loic Le Marchand, Zuo-Feng Zhang, John K Field, Hermann Brenner, Nancy Diao, Juntao Xie, Takashi Kohno, Curtis C Harris, Angela S Wenzlaff, Guillermo Fernandez-Tardon, Yuanqing Ye, Fiona Taylor, Lynne R Wilkens, Michael Davies, Yi Liu, Matt J Barnett, Gary E Goodman, Hal Morgenstern, Bernd Holleczek, Sera Thomas, M Catherine Brown, Rayjean J Hung, Wei Xu, and Geoffrey Liu
Protein-altering germline mutations implicate novel genes related to lung cancer development., Xuemei Ji, Semanti Mukherjee, Maria Teresa Landi, Yohan Bosse, Philippe Joubert, Dakai Zhu, Ivan Gorlov, Xiangjun Xiao, Younghun Han, Olga Gorlova, Rayjean J Hung, Yonathan Brhane, Robert Carreras-Torres, David C Christiani, Neil Caporaso, Mattias Johansson, Geoffrey Liu, Stig E Bojesen, Loic Le Marchand, Demetrios Albanes, Heike Bickeböller, Melinda C Aldrich, William S Bush, Adonina Tardon, Gad Rennert, Chu Chen, Jinyoung Byun, Konstantin H Dragnev, John K Field, Lambertus Fa Kiemeney, Philip Lazarus, Shan Zienolddiny, Stephen Lam, Matthew B Schabath, Angeline S Andrew, Pier A Bertazzi, Angela C Pesatori, Nancy Diao, Li Su, Lei Song, Ruyang Zhang, Natasha Leighl, Jakob S Johansen, Anders Mellemgaard, Walid Saliba, Christopher Haiman, Lynne Wilkens, Ana Fernandez-Somoano, Guillermo Fernandez-Tardon, Erik H F M van der Heijden, Jin Hee Kim, Michael P A Davies, Michael W Marcus, Hans Brunnström, Jonas Manjer, Olle Melander, David C Muller, Kim Overvad, Antonia Trichopoulou, Rosario Tumino, Gary E Goodman, Angela Cox, Fiona Taylor, Penella Woll, Erich Wichmann, Thomas Muley, Angela Risch, Albert Rosenberger, Kjell Grankvist, Mikael Johansson, Frances Shepherd, Ming-Sound Tsao, Susanne M Arnold, Eric B Haura, Ciprian Bolca, Ivana Holcatova, Vladimir Janout, Milica Kontic, Jolanta Lissowska, Anush Mukeria, Simona Ognjanovic, Tadeusz M Orlowski, Ghislaine Scelo, Beata Swiatkowska, David Zaridze, Per Bakke, Vidar Skaug, Lesley M Butler, Kenneth Offit, Preethi Srinivasan, Chaitanya Bandlamudi, Matthew D Hellmann, David B Solit, Mark E Robson, Charles M Rudin, Zsofia K Stadler, Barry S Taylor, Michael F Berger, Richard Houlston, John McLaughlin, Victoria Stevens, David C Nickle, Ma'en Obeidat, Wim Timens, María Soler Artigas, Sanjay Shete, Hermann Brenner, Stephen Chanock, Paul Brennan, James D McKay, and Christopher I Amos
CX-2029, a PROBODY drug conjugate targeting CD71 (transferrin receptor): Results from a first-in-human study (PROCLAIM-CX-2029) in patients (Pts) with advanced cancer., Melissa Lynne Johnson, Anthony B. El-Khoueiry, Navid Hafez, Nehal J. Lakhani, Hirva Mamdani, Jordi Rodon Ahnert, Rachel E Sanborn, Thang Ho, Rachel Li, Jana Waldes, and Alexander I. Spira
MIPS participation in radiation oncology practices-A simple survey., Ryan T Jones, Mary Jo Tarrant, Dominick Parris, Michael Ray, and Join Y Luh
Nivolumab in Advanced Hepatocellular Carcinoma: Safety Profile and Select Treatment-Related Adverse Events From the CheckMate 040 Study., Karen Julien, Hiu Tung Leung, Carmen Fuertes, Megumi Mori, Miao-Jen Wang, Jocelyn Teo, Lisa Weiss, Sara Hamilton, Holly DiFebo, Yoon Jin Noh, Aralee Galway, Jane Koh, Edith Brutcher, Huanyu Zhao, Yun Shen, Marina Tschaika, and Yue-Yun To
Comparative lipidomics of 5-Fluorouracil-sensitive and -resistant colorectal cancer cells reveals altered sphingomyelin and ceramide controlled by acid sphingomyelinase (SMPD1)., Jae Hun Jung, Kohei Taniguchi, Hyeong Min Lee, Min Young Lee, Raju Bandu, Kazumasa Komura, Kil Yeon Lee, Yukihiro Akao, and Kwang Pyo Kim
Maximizing Breast Cancer Therapy with Awareness of Potential Treatment-Related Blood Disorders., Henry G Kaplan, Gregory S Calip, and Judith A Malmgren
Breast cancer distant recurrence lead time interval by detection method in an institutional cohort., Henry G Kaplan, Judith A Malmgren, and Mary K Atwood
Pre/perimenopausal (preMeno) women receiving palbociclib (PAL) for hormone receptor-positive (HR+)/human epidermal growth factor receptor 2-negative (HER2‒) advanced breast cancer (ABC) in a real-world setting: Treatment patterns from POLARIS, MS Karuturi, A Garrett, JL Blum, J Anderson, E Jensen, T Pluard, Thomas Stanton, K Manning, JC Cappelleri, F Beery, Y Wang, and D Tripathy
MP70-07 TRANSPERINEAL FOCAL CRYOABLATION AS A TREATMENT FOR CLINICALLY SIGNIFICANT PROSTATE CANCER, Mark J. Kelly and Jonatan Torrez
Tumor slice culture as a biologic surrogate of human cancer., Heidi L Kenerson, Kevin M Sullivan, Yongwoo D Seo, Kathryn M Stadeli, Cigdem Ussakli, Xiaowei Yan, Christopher G Lausted, Venu G Pillarisetty, James O Park, Kimberly J Riehle, Matthew Yeh, Qiang Tian, and Raymond S Yeung
Delay in surgery is associated with axillary upstaging of clinically node negative breast cancer patients., Adam Khader, Shu-Ching Chang, Juan A Santamaria-Barria, Mary Garland-Kledzik, Anthony J Scholer, Melanie Goldfarb, Janie Grumley, and Trevan D Fischer
BRAINSTORM: A Multi-Institutional Phase 1/2 Study of RRx-001 in Combination With Whole Brain Radiation Therapy for Patients With Brain Metastases., Michelle M Kim, Hemant A Parmar, Matthew Schipper, Theresa Devasia, Madhava P Aryal, Santosh Kesari, Steven J O'Day, Aki Morikawa, Daniel E Spratt, Larry Junck, Aaron Mammoser, James A Hayman, Theodore S Lawrence, Christina I Tsien, Robert Aiken, Sharad Goyal, Nacer Abrouk, Malcolm Trimble, Yue Cao, and Christopher D Lao
Targeting breast cancer metabolism with a novel inhibitor of mitochondrial ATP synthesis., Myoung Sook Kim, Ramkishore Gernapudi, Yessenia Cedeño Cedeño, Brian M Polster, Ramon Martinez, Paul Shapiro, Santosh Kesari, Elmar Nurmemmedov, and Antonino Passaniti
"Chemotherapy-periodized" Exercise to Accommodate for Cyclical Variation in Fatigue., Amy A Kirkham, Kelcey A Bland, David S Zucker, Joshua Bovard, Tamara Shenkier, Donald C McKenzie, Margot K Davis, Karen A Gelmon, and Kristin L Campbell
Inflammatory and clinical risk factors for chemotherapy-induced peripheral neuropathy (CIPN): A nationwide longitudinal study in 143 cancer patients during chemotherapy., Ian Kleckner, Todd Jusko, Eva Culakova, Amber Kleckner, Matthew Asare, Julia Ellen Inglis, Kah Poh Loh, Luke Joseph Peppone, Jeffrey L. Berenberg, Alison Conlin, Deborah J. Ossip, and Karen Michelle Mustian
Primary chemoablation of low-grade upper tract urothelial carcinoma using UGN-101, a mitomycin-containing reverse thermal gel (OLYMPUS): an open-label, single-arm, phase 3 trial., Nir Kleinmann, Surena F Matin, Phillip M Pierorazio, John L Gore, Ahmad Shabsigh, Brian Hu, Karim Chamie, Guilherme Godoy, Scott Hubosky, Marcelino Rivera, Michael O'Donnell, Marcus Quek, Jay D Raman, John J Knoedler, Douglas Scherr, Joshua Stern, Christopher Weight, Alon Weizer, Michael Woods, Hristos Kaimakliotis, Angela B Smith, Jennifer M Linehan, Jonathan Coleman, Mitchell R Humphreys, Raymond Pak, David Lifshitz, Michael Verni, Mehrad Adibi, Mahul B Amin, Elyse Seltzer, Ifat Klein, Marina Konorty, Dalit Strauss-Ayali, Gil Hakim, Mark Schoenberg, and Seth P Lerner
Management of CLL Patients Early in the COVID-19 Pandemic: An International Survey of CLL Experts, Brian Koffman, Anthony Mato, John C. Byrd, Alexey Danilov, Brad Hedrick, Chaitra Ujjani, Lindsey Roeker, Deborah M. Stephens, Matthew S. Davids, John M Pagel, and Mazyar Shadman
760 Trough levels of ipilimumab in serum as a potential predictive biomarker of clinical outcomes for patients with advanced melanoma after treatment with ipilimumab, Yoshinobu Koguchi, Noriko Iwamoto, Takashi Shimada, Shu-Ching Chang, John Cha, Brian D. Piening, Brendan Curti, Walter Urba, and William L. Redmond
760 Trough levels of ipilimumab in serum as a potential predictive biomarker of clinical outcomes for patients with advanced melanoma after treatment with ipilimumab, Yoshinobu Koguchi, Noriko Iwamoto, Takashi Shimada, Shu-Ching Chang, John Cha, Brian D. Piening, Brian Piening, Brendan Curti, Walter Urba, and William L. Redmond
ANG1005, a brain penetrating peptide-drug conjugate, shows activity in patients with breast cancer with leptomeningeal carcinomatosis and recurrent brain metastases., Priya Kumthekar, Shou-Ching Tang, Andrew J Brenner, Santosh Kesari, David E Piccioni, Carey K Anders, Jose A Carrillo, Pavani Chalasani, Peter Kabos, Shannon L Puhalla, Katherine H R Tkaczuk, Agustin Garcia, Manmeet S Ahluwalia, Jeffrey S Wefel, Nehal Lakhani, and Nuhad K Ibrahim
Ineffective esophageal motility is not a contraindication to total fundoplication., Anne-Sophie Laliberte, Brian Louie, Candice Wilshire, Alexander S Farivar, Adam J Bograd, and Ralph W Aye
COVID-19 and cancer: A guide with suggested COVID-19 rule-out criteria to support clinical decision-making., Christopher Larson, Bryan Oronsky, Sharad Goyal, Carolyn Ray, Farah Hedjran, Terese C Hammond, Santosh Kesari, Scott Caroen, Michelle Lybeck, Vaughn E Dobalian, Arnold Oronsky, and Tony Reid
Phase 1 study of CWP232291 in patients with relapsed or refractory acute myeloid leukemia and myelodysplastic syndrome., Je-Hwan Lee, Stefan Faderl, John M Pagel, Chul Won Jung, Sung-Soo Yoon, Animesh D Pardanani, Pamela S Becker, Howard Lee, Jeongeun Choi, Kyoungjune Lee, Minkyoung Kim, and Jorge E Cortes
