Submissions from 2021
The regulatory saga of fedratinib., Shannon Khal, Vinay Prasad, and Alison Palumbo
"Custom" Plate in a Day-Accurate Predictive Hole Fabrication Using Point-of-Care 3-Dimensional Printing., Baber Khatib, Marcus Couey, Ashish Patel, Allen C Cheng, and Richard Bryan Bell
Machine learning models to predict failure in administration of intrapleural tPA/DNase in patients with complicated parapneumonic effusions/empyema: A multicenter study, D Khemasuwan, S Shojaee, C Reddy, CR Gilbert, JA Gorden, A Balwan, S Trinidad, B Bixby, JS Sorensen, and Candice L. Wilshire
Machine learning models to predict failure in administration of intrapleural tPA/DNase in patients with complicated parapneumonic effusions/empyema: A multicenter study, D Khemasuwan, S Shojaee, C Reddy, CR Gilbert, JA Gorden, A Balwan, S Trinidad, B Bixby, JS Sorensen, and Candice L. Wilshire
A Case Series of Metastatic Metaplastic Breast Carcinoma Treated With Anti-PD-1 Therapy., Isaac Kim, Venkatesh Rajamanickam, Brady Bernard, Brie Chun, Yaping Wu, Maritza Martel, Zhaoyu Sun, William L Redmond, Katherine Sanchez, Reva Basho, Heather McArthur, and David B Page
Improved image reconstruction of, Julian Kirchner, Joseph A O'Donoghue, Anton S Becker, and Gary A Ulaner
Awareness, Knowledge, and Preferences of United States (US) Patients with Chronic Lymphocytic Leukemia (CLL) and Their Caregivers Related to Finite Duration (FD) Therapy and Minimal (Measurable) Residual Disease (MRD), Brian Koffman, Neil Bailey, John M Pagel, and See all authors in comments
Trough levels of ipilimumab in serum as a potential biomarker of clinical outcomes for patients with advanced melanoma after treatment with ipilimumab., Yoshinobu Koguchi, Noriko Iwamoto, Takashi Shimada, Shu-Ching Chang, John Cha, Brendan Curti, Walter Urba, Brian D. Piening, and William L. Redmond
Genomic and functional characterization of a mucosal symbiont involved in early-stage colorectal cancer., Melissa C Kordahi, Ian B Stanaway, Marion Avril, Denise Chac, Marie-Pierre Blanc, Benjamin Ross, Christian Diener, Sumita Jain, Paul McCleary, Ana Parker, Vincent Friedman, Jennifer Huang, Wynn Burke, Sean M Gibbons, Amy D Willis, Richard P Darveau, William M Grady, Cynthia W Ko, and R William DePaolo
Changes in Carcinoid Syndrome Symptoms Among Patients Receiving Telotristat Ethyl in US Clinical Practice: Findings from the TELEPRO-II Real-World Study., Matthew H Kulke, Hagen F Kennecke, Kris Murali, and Vijay N Joish
Quality Is King: Fundamental Insights into Tumor Antigenicity from Virus-Associated Merkel Cell Carcinoma., Miranda C Lahman, Kelly G Paulson, Paul T Nghiem, and Aude G Chapuis
An empirical antigen selection method identifies neoantigens that either elicit broad anti-tumor T cell responses or drive tumor growth., Hubert Lam, Lisa K McNeil, Hanna Starobinets, Victoria L DeVault, Roger B Cohen, Przemyslaw Twardowski, Melissa L Johnson, Maura L Gillison, Mark N Stein, Ulka N Vaishampayan, Arthur P DeCillis, James J Foti, Vijetha Vemulapalli, Emily Tjon, Kyle Ferber, Daniel B DeOliveira, Wendy Broom, Parul Agnihotri, Elizabeth M Jaffee, Kwok-Kin Wong, Charles G Drake, Pamela M Carroll, Thomas A Davis, and Jessica Baker Flechtner
Unaltered IL-2 encapsulated in acoustically active lipid microspheres for systemic but targeted microdose delivery to tumor microenvironment., Clayton Larsen, Llew Keltner, William L. Redmond, and Rhodemann Li
Pregnancy outcomes in women with epilepsy and MTHFR mutations supplemented with methylated folate and methylcobalamin (methylated B12)., Emma M Lascar, Nicole M Warner, and Michael J Doherty
WNT Signaling as a Therapeutic Target for Glioblastoma., Michael Latour, Nam-Gu Her, Santosh Kesari, and Elmar Nurmemmedov
Lung cancer diagnosed on pap smear: A case report and review of the literature., Marie-Claire Leaf, Diana Pearre, Fabio Cappuccini, and Krishnansu S Tewari
Lenvatinib plus pembrolizumab in patients with either treatment-naive or previously treated metastatic renal cell carcinoma (Study 111/KEYNOTE-146): a phase 1b/2 study., Chung-Han Lee, Amishi Yogesh Shah, Drew Rasco, Arpit Rao, Matthew H Taylor, Christopher Di Simone, James J Hsieh, Alvaro Pinto, David R Shaffer, Regina Girones Sarrio, Allen Lee Cohn, Nicholas J Vogelzang, Mehmet Asim Bilen, Sara Gunnestad Ribe, Musaberk Goksel, Øyvind Krohn Tennøe, Donald Richards, Randy F Sweis, Jay Courtright, Daniel Heinrich, Sharad Jain, Jane Wu, Emmett V Schmidt, Rodolfo F Perini, Peter Kubiak, Chinyere E Okpara, Alan D Smith, and Robert J Motzer
Cordycepin inhibits the proliferation of malignant peripheral nerve sheath tumor cells through the p53/Sp1/tubulin pathway., Ming-Jen Lee, Jen-Chieh Lee, Jung-Hsien Hsieh, May-Yao Lin, I-An Shih, Huey-Ling You, and Kai Wang
Molecular interaction of HIC, an agonist of P2Y1 receptor, and its role in prostate cancer apoptosis., Hien Thi Thu Le, Akshaya Murugesan, Thiyagarajan Ramesh, Olli Yli-Harja, Saravanan Konda Mani, and Meenakshisundaram Kandhavelu
Neoadjuvant immunoradiotherapy results in high rate of complete pathological response and clinical to pathological downstaging in locally advanced head and neck squamous cell carcinoma., Rom Leidner, Marka Crittenden, Kristina Young, Hong Xiao, Yaping Wu, Marcus A Couey, Ashish A Patel, Allen C Cheng, Amber L Watters, Carlo Bifulco, George Morris, Lessli Rushforth, Shorin Nemeth, Walter J Urba, Michael Gough, and R Bryan Bell
Cancer microenvironment and genomics: evolution in process., Stanley P Leong, Isaac P Witz, Orit Sagi-Assif, Sivan Izraely, Jonathan Sleeman, Brian Piening, Bernard A Fox, Carlo B Bifulco, Rachel Martini, Lisa Newman, Melissa Davis, Lauren M Sanders, David Haussler, Olena M Vaske, and Marlys Witte
Beyond Sedlis-A novel histology-specific nomogram for predicting cervical cancer recurrence risk: An NRG/GOG ancillary analysis., Kimberly Levinson, Anna L Beavis, Christopher Purdy, Anne F Rositch, Akila Viswanathan, Aaron H Wolfson, Michael G Kelly, Krishnansu S Tewari, Leah McNally, Saketh R Guntupalli, Omar Ragab, Yi-Chun Lee, David S Miller, Warner K Huh, Kelly J Wilkinson, Nicola M Spirtos, Linda Van Le, Yovanni Casablanca, Laura L Holman, Steven E Waggoner, and Amanda N Fader
Pembrolizumab with low-dose carboplatin for recurrent platinum-resistant ovarian, fallopian tube, and primary peritoneal cancer: survival and immune correlates., John B Liao, William R Gwin, Renata R Urban, Katie M Hitchcock-Bernhardt, Andrew L Coveler, Doreen M Higgins, Jennifer S Childs, Hania N Shakalia, Ron E Swensen, Sasha E Stanton, Anna V Tinker, Tanya A Wahl, Richard G Ancheta, Kathryn F McGonigle, James Y Dai, Mary L Disis, and Barbara A Goff
Disrupting tumour vasculature and recruitment of aPDL1-loaded platelets control tumour metastasis., Hongjun Li, Zejun Wang, Zhaowei Chen, Tianyuan Ci, Guojun Chen, Di Wen, Ruoxin Li, Jinqiang Wang, Huan Meng, R Bryan Bell, Zhifeng Gu, Gianpietro Dotti, and Zhen Gu
Measurements of Functional Network Connectivity Using Resting State Arterial Spin Labeling During Neurosurgery., Thomas Lindner, Hajrullah Ahmeti, Michael Helle, Olav Jansen, Jens Fiehler, Lasse Dührsen, Michael Synowitz, Santosh Kesari, and Stephan Ulmer
Effects of yoga, cognitive behavioral therapy, and a behavioral placebo on sleep: A nationwide multicenter phase III RCT in cancer survivors., Po-Ju Lin, Charles E. Heckler, Alison Conlin, and See full list of authors in comments
Improved Survival Outcomes in Medically Fit Patients With Early-Stage Non-Small-Cell Lung Cancer Undergoing Stereotactic Body Radiotherapy., Jason Liu, Caressa Hui, Colton Ladbury, Thomas Waddington, Loretta Erhunmwunsee, Dan Raz, Jae Kim, Ravi Salgia, Stafford Chenery, Daryl Pearlstein, Amanda Schwer, and Arya Amini
Niraparib in the maintenance treatment of advanced epithelial ovarian, fallopian tube, or primary peritoneal cancer: safety and efficacy., Marisa C Liu, Joyce Sutedja, and Krishnansu S Tewari
Characterization of the immune response in patients with cancer of the oral cavity after neoadjuvant immunotherapy with the IRX-2 regimen., Siyu Liu, Emily Bellile, Ariane Nguyen, Katie Zarins, Nisha D'Silva, Laura Rozek, Gregory T Wolf, Maureen A Sartor, INSPIRE Trial Clinical Investigators, and Richard Bryan Bell
Epigenetic Regulation of Immunotherapy Response in Triple-Negative Breast Cancer., Pere Llinàs-Arias, Sandra Íñiguez-Muñoz, Kelly McCann, Leonie Voorwerk, Javier I J Orozco, Miquel Ensenyat-Mendez, Borja Sesé, Maggie L DiNome, and Diego M Marzese
Axicabtagene Ciloleucel as Second-Line Therapy for Large B-Cell Lymphoma., Frederick L Locke, David B Miklos, Caron A Jacobson, Miguel-Angel Perales, Marie-José Kersten, Olalekan O Oluwole, Armin Ghobadi, Aaron P Rapoport, Joseph McGuirk, John M Pagel, Javier Muñoz, Umar Farooq, Tom van Meerten, Patrick M Reagan, Anna Sureda, Ian W Flinn, Peter Vandenberghe, Kevin W Song, Michael Dickinson, Monique C Minnema, Peter A Riedell, Lori A Leslie, Sridhar Chaganti, Yin Yang, Simone Filosto, Jina Shah, Marco Schupp, Christina To, Paul Cheng, Leo I Gordon, Jason R Westin, and All ZUMA-7 Investigators and Contributing Kite Members
Caregiver-Oncologist Prognostic Concordance, Caregiver Mastery, and Caregiver Psychological Health and Quality of Life., Kah Poh Loh, Mostafa R Mohamed, Sindhuja Kadambi, Eva Culakova, Huiwen Xu, Allison Magnuson, Marie Flannery, Paul R Duberstein, Ronald M Epstein, Colin McHugh, Ryan D Nipp, Kelly M Trevino, Chandrika Sanapala, Bianca A Hall, Beverly Canin, Arlene A Gayle, Alison Conlin, James Bearden, and Supriya G Mohile
Characterization of outcomes and practices utilized in the management of internal carotid artery injury not requiring definitive endovascular management., Nyall R London, Abdulaziz AlQahtani, Siani Barbosa, Paolo Castelnuovo, Davide Locatelli, Aldo Stamm, Aaron A Cohen-Gadol, Hussam Elbosraty, Roy Casiano, Jacques Morcos, Ernesto Pasquini, Georgio Frank, Diego Mazzatenta, Garni Barkhoudarian, Chester Griffiths, Daniel Kelly, Christos Georgalas, Trichy N Janakiram, Piero Nicolai, Daniel M Prevedello, and Ricardo L Carrau
Standard-Dose Pembrolizumab Plus Alternate-Dose Ipilimumab in Advanced Melanoma: KEYNOTE-029 Cohort 1C, a Phase 2 Randomized Study of Two Dosing Schedules., Georgina V Long, Caroline Robert, Marcus O Butler, Felix Couture, Matteo S Carlino, Steven O'Day, Victoria Atkinson, Jonathan S Cebon, Michael P Brown, Stephane Dalle, Andrew G Hill, Geoffrey T Gibney, Steven McCune, Alexander M Menzies, Cuizhen Niu, Nageatte Ibrahim, Blanca Homet Moreno, and Adi Diab
A CRISPR/Cas9-engineered ARID1A-deficient human gastric cancer organoid model reveals essential and non-essential modes of oncogenic transformation., Yuan-Hung Lo, Kevin S Kolahi, Yuhong Du, Chiung-Ying Chang, Andrey Krokhotin, Ajay Nair, Walter D Sobba, Kasper Karlsson, Sunny J Jones, Teri A Longacre, Amanda T Mah, Bahar Tercan, Alexandra Sockell, Hang Xu, Jose A Seoane, Jin Chen, Ilya Shmulevich, Jonathan S Weissman, Christina Curtis, Andrea Califano, Haian Fu, Gerald R Crabtree, and Calvin J Kuo
Beyond the Chemotherapy Certificate: Building a Knowledge Base Virtually for Oncology Nursing Practice Across a Health System., Julianne Luttrell, Sarah Sumner, Emy-Lee Marie Anglo Ricafrente, and Marlon G Saria
Resolution of tissue signatures of therapy response in patients with recurrent GBM treated with neoadjuvant anti-PD1., Yue Lu, Alphonsus H C Ng, Frances E Chow, Richard G Everson, Beth A Helmink, Michael T Tetzlaff, Rohit Thakur, Jennifer A Wargo, Timothy F Cloughesy, Robert M Prins, and James R Heath
Coinfection of, Samragnyi Madala, Kira MacDougall, Balarama Krishna Surapaneni, Robin Park, Mohit Girotra, and Anup Kasi
Neoadjuvant immunotherapy is reshaping cancer management across multiple tumour types: The future is now!, Michele Maio, Christian Blank, Andrea Necchi, Anna Maria Di Giacomo, Ramy Ibrahim, Michael Lahn, Bernard A Fox, R Bryan Bell, Giampaolo Tortora, and Alexander M M Eggermont
A vision of immuno-oncology: the Siena think tank of the Italian network for tumor biotherapy (NIBIT) foundation., Michele Maio, Michael Lahn, Anna Maria Di Giacomo, Alessia Covre, Luana Calabrò, Ramy Ibrahim, Bernard Fox, and Siena Think Tank
354 Lenvatinib and pembrolizumab in advanced endometrial carcinoma (EC): long-term efficacy and safety update from a phase 1b/2 study, Vicky Makker, Matthew H Taylor, and See full list of authors in comments
Streamlining brain tumor surgery care during the COVID-19 pandemic: A case-control study., Regin Jay Mallari, Michael B Avery, Alex Corlin, Amalia Eisenberg, Terese C Hammond, Neil A Martin, Garni Barkhoudarian, and Daniel F Kelly
Endoscopic Endonasal and Supraorbital Removal of Tuberculum Sellae Meningiomas: Anatomic Guides and Operative Nuances for Keyhole Approach Selection., Regin Jay Mallari, Jai Deep Thakur, John H Rhee, Amalia Eisenberg, Howard Krauss, Chester Griffiths, Walavan Sivakumar, Garni Barkhoudarian, and Daniel F Kelly
Adjuvant T-DM1 versus trastuzumab in patients with residual invasive disease after neoadjuvant therapy for HER2-positive breast cancer: subgroup analyses from KATHERINE., E P Mamounas, M Untch, M S Mano, C-S Huang, C E Geyer, G von Minckwitz, N Wolmark, X Pivot, S Kuemmel, M P DiGiovanna, B Kaufman, G Kunz, A K Conlin, J C Alcedo, T Kuehn, I Wapnir, A Fontana, J Hackmann, J Polikoff, M Saghatchian, A Brufsky, Y Yang, M Zimovjanova, T Boulet, H Liu, D Tesarowski, L H Lam, C Song, M Smitt, and S Loibl
Prognostic gene expression signatures of breast cancer are lacking a sensible biological meaning., Kalifa Manjang, Shailesh Tripathi, Olli Yli-Harja, Matthias Dehmer, Galina Glazko, and Frank Emmert-Streib
Limitations of Explainability for Established Prognostic Biomarkers of Prostate Cancer., Kalifa Manjang, Olli Yli-Harja, Matthias Dehmer, and Frank Emmert-Streib
A phase I/II study of rovalpituzumab tesirine in delta-like 3-expressing advanced solid tumors., Aaron S Mansfield, David S Hong, Christine L Hann, Anna F Farago, Himisha Beltran, Saiama N Waqar, Andrew E Hendifar, Lowell B Anthony, Matthew H Taylor, Alan H Bryce, Scott T Tagawa, Karl Lewis, Jiaxin Niu, Christine H Chung, James M Cleary, Michael Rossi, Carrianne Ludwig, Ricardo Valenzuela, Yan Luo, and Rahul Aggarwal
Trifluridine/tipiracil in patients with metastatic gastroesophageal junction cancer: a subgroup analysis from the phase 3 TAGS study., Wasat Mansoor, Hendrik-Tobias Arkenau, Maria Alsina, Kohei Shitara, Peter Thuss-Patience, Sinead Cuffe, Mikhail Dvorkin, David Park, Takayuki Ando, Marc Van Den Eynde, Giordano D Beretta, Alberto Zaniboni, Toshihiko Doi, Josep Tabernero, David H Ilson, Lukas Makris, Karim A Benhadji, and Eric Van Cutsem
Large polyps: Pearls for the referring and receiving endoscopist., Eric Markarian, Brian M Fung, Mohit Girotra, and James H Tabibian
Defining Risk Categories for a Significant Decline in Estimated Glomerular Filtration Rate After Robotic Partial Nephrectomy: Implications for Patient Follow-up., Alberto Martini, Ugo Giovanni Falagario, Shivaram Cumarasamy, Ronney Abaza, Daniel D Eun, Akshay Bhandari, James R Porter, Ashok K Hemal, and Ketan K Badani
Phosphorylation of SMAD3 in immune cells predicts survival of patients with early stage non-small cell lung cancer., Sebastian Marwitz, Carmen Ballesteros-Merino, Shawn M. Jensen, Martin Reck, Christian Kugler, Sven Perner, Daniel Drömann, Torsten Goldmann, and Bernard A Fox
Durability of Response to Primary Chemoablation of Low-Grade Upper Tract Urothelial Carcinoma Using UGN-101, a Mitomycin-Containing Reverse Thermal Gel: OLYMPUS Trial Final Report., Surena F Matin, Phillip M Pierorazio, Nir Kleinmann, John L Gore, Ahmad Shabsigh, Brian Hu, Karim Chamie, Guilherme Godoy, Scott G Hubosky, Marcelino Rivera, Michael O'Donnell, Marcus Quek, Jay D Raman, John J Knoedler, Douglas Scherr, Christopher Weight, Alon Weizer, Michael Woods, Hristos Kaimakliotis, Angela B Smith, Jennifer M Linehan, Jonathan Coleman, Mitchell R Humphreys, Raymond Pak, David Lifshitz, Michael Verni, Ifat Klein, Marina Konorty, Dalit Strauss-Ayali, Gil Hakim, Elyse Seltzer, Mark Schoenberg, and Seth P Lerner
Recognizing Unmet Need in the Era of Targeted Therapy for CLL/SLL: "What's Past Is Prologue" (Shakespeare)., Anthony R Mato, Matthew S Davids, Jeff Sharman, Lindsey E Roeker, Neil Kay, Arnon Kater, Kerry Rogers, Meghan C Thompson, Joanna Rhodes, Andre Goy, Alan Skarbnik, Stephen J Schuster, Constantine S Tam, Toby A Eyre, Susan O'Brien, Chadi Nabhan, Nicole Lamanna, Clare Sun, Mazyar Shadman, John M Pagel, Chaitra Ujjani, Danielle Brander, Catherine C Coombs, Nitin Jain, Chan Y Cheah, Jennifer R Brown, John F Seymour, and Jennifer A Woyach
Pirtobrutinib in relapsed or refractory B-cell malignancies (BRUIN): a phase 1/2 study., Anthony R Mato, Nirav N Shah, Wojciech Jurczak, Chan Y Cheah, John M Pagel, Jennifer A Woyach, Bita Fakhri, Toby A Eyre, Nicole Lamanna, Manish R Patel, Alvaro Alencar, Ewa Lech-Maranda, William G Wierda, Catherine C Coombs, James N Gerson, Paolo Ghia, Steven Le Gouill, David John Lewis, Suchitra Sundaram, Jonathon B Cohen, Ian W Flinn, Constantine S Tam, Minal A Barve, Bryone Kuss, Justin Taylor, Omar Abdel-Wahab, Stephen J Schuster, M Lia Palomba, Katharine L Lewis, Lindsey E Roeker, Matthew S Davids, Xuan Ni Tan, Timothy S Fenske, Johan Wallin, Donald E Tsai, Nora C Ku, Edward Zhu, Jessica Chen, Ming Yin, Binoj Nair, Kevin Ebata, Narasimha Marella, Jennifer R Brown, and Michael Wang
Vertebral Augmentation of Cancer-Related Spinal Compression Fractures: A Systematic Review and Meta-Analysis., Ryan Mattie, Nick Brar, Jennifer T Tram, Zachary L McCormick, Douglas P Beall, Andrew Fox, and Mikhail Saltychev
How we approach hemangiomas in infants., Jennifer L R Mayer, Stefanos Intzes, Vikash S Oza, and Francine Blei
A Microcosm of Disparities in Breast Cancer: Comparison Between a Private Hospital and a Safety-Net County Hospital Within Los Angeles County., Natalie C McClintock, Reed I Ayabe, Ruben D Salas Parra, Amy H Kaji, Javier I Orozco, Diego M Marzese, Estela Samuels, Stacey L Stern, Christine Dauphine, and Junko J Ozao-Choy
Micro-Loss; Expanding Our Vocabulary to Describe Grief during the Time of Covid., Danielle McLaughlin
Electronic Charting of Radiation Therapy Planning and Treatment: Report of Task Group 262., James G Mechalakos, Sonja Dieterich, Luis E Fong de Los Santos, Sandra C Fontenla, Joseph Hanley, Vijay A Harwalkar, Linda X Hong, Y Jessica Huang, Grace Gwe-Ya Kim, Susan L Richardson, Steven G Sutlief, Sridhar Yaddanapudi, Sue Merkel, and Mark Parry
Defining Immunogenic and Radioimmunogenic Tumors., Terry R Medler, Tiffany C Blair, Marka R Crittenden, and Michael J Gough
Complicated pleural space infections are associated with prolonged recovery and reduced work effectiveness Chest 2021 Annual Meeting Orlando, Florida, AM Meggyesy, Candice L. Wilshire, and See all authors in comments
Outpatient thoracentesis for pleural effusion following cardiac surgery appears safe with ongoing anticoagulation and antiplatelet use Chest 2021 Annual Meeting Orlando, Florida, AM Meggyesy, Candice L. Wilshire, and See all authors in comments
Pectoral muscle area correlates with LENT score in non-small cell lung cancer-associated pleural effusion survival prediction The International Association for the Study of Lung Cancer 2020 World Conference on Lung Cancer Worldwide Virtual Event, AM Meggyesy, Candice L. Wilshire, and See all authors in comments
Repeat thoracenteses is associated with an increase in cumulative risk of complications in patients with a malignant pleural effusion The American Thoracic Society San Diego, California, HE Modin, Candice L. Wilshire, and See all authors in comments
Translational Advances in Cancer Prevention Agent Development (TACPAD) Virtual Workshop on Immunomodulatory Agents: Report., Altaf Mohammed, Roderick H Dashwood, Sally Dickinson, Mary L Disis, Elizabeth M Jaffee, Bryon D Johnson, Samir N Khleif, Michael N Pollak, Jeffrey Schlom, Robert H Shoemaker, Sasha Stanton, Georg T Wondrak, Ming You, Hao Zhu, and Mark Steven Miller
A Randomized Trial of Fulvestrant, Everolimus, and Anastrozole for the Front-line Treatment of Patients with Advanced Hormone Receptor-positive Breast Cancer, SWOG S1222., Halle C F Moore, William E Barlow, George Somlo, Julie R Gralow, Anne F Schott, Daniel F Hayes, Peter Kuhn, James B Hicks, Lisa Welter, Philip A Dy, Christina H Yeon, Alison Conlin, Ernie Balcueva, Danika L Lew, Debasish Tripathy, Lajos Pusztai, and Gabriel N Hortobagyi
Atezolizumab, Bevacizumab, and Chemotherapy for Newly Diagnosed Stage III or IV Ovarian Cancer: Placebo-Controlled Randomized Phase III Trial (IMagyn050/GOG 3015/ENGOT-OV39)., Kathleen N Moore, Michael Bookman, Jalid Sehouli, Austin Miller, Charles Anderson, Giovanni Scambia, Tashanna Myers, Cagatay Taskiran, Katina Robison, Johanna Mäenpää, Lyndsay Willmott, Nicoletta Colombo, Jessica Thomes-Pepin, Michalis Liontos, Michael A Gold, Yolanda Garcia, Sudarshan K Sharma, Christopher J Darus, Carol Aghajanian, Aikou Okamoto, Xiaohua Wu, Rustem Safin, Fan Wu, Luciana Molinero, Vidya Maiya, Victor K Khor, Yvonne G Lin, and Sandro Pignata
HDAC inhibition prevents transgene expression downregulation and loss-of-function in T-cell-receptor-transduced T cells., Tamson V Moore, Gina M Scurti, Matthew DeJong, Siao-Yi Wang, Annika V Dalheim, Courtney R Wagner, Kelli A Hutchens, Jodi J Speiser, Constantine V Godellas, Chris Fountain, Jessica Fleser, Tarsem Moudgil, Mallory Thomas, David Murray, Brendan D Curti, Joseph I Clark, Bernard A Fox, and Michael I Nishimura
Neoadjuvant Pelvic Radiotherapy in the Management of Rectal Cancer with Synchronous Liver Metastases: Is It Worth It?, Maitham A Moslim, Amir L Bastawrous, and D Rohan Jeyarajah
Lenvatinib plus Pembrolizumab or Everolimus for Advanced Renal Cell Carcinoma., Robert Motzer, Boris Alekseev, Sun-Young Rha, Camillo Porta, Masatoshi Eto, Thomas Powles, Viktor Grünwald, Thomas E Hutson, Evgeny Kopyltsov, María J Méndez-Vidal, Vadim Kozlov, Anna Alyasova, Sung-Hoo Hong, Anil Kapoor, Teresa Alonso Gordoa, Jaime R Merchan, Eric Winquist, Pablo Maroto, Jeffrey C Goh, Miso Kim, Howard Gurney, Vijay Patel, Avivit Peer, Giuseppe Procopio, Toshio Takagi, Bohuslav Melichar, Frederic Rolland, Ugo De Giorgi, Shirley Wong, Jens Bedke, Manuela Schmidinger, Corina E Dutcus, Alan D Smith, Lea Dutta, Kalgi Mody, Rodolfo F Perini, Dongyuan Xing, Toni K Choueiri, CLEAR Trial Investigators, and Brendan Curti (CLEAR Trial Investigators)
85 Detection of human angiotensin-converting enzyme 2 receptor (hACE2R) on human cancer cell lines, Tarsem Moudgil, Bernard A Fox, and Hong-Ming Hu
Induction of ADAM10 by RT drives fibrosis, resistance, and EMT in pancreatic cancer., Adam C Mueller, Miles Piper, Andrew Goodspeed, Shiv Bhuvane, Jason S Williams, Shilpa Bhatia, Andy V Phan, Benjamin Van Court, Kathryn L Zolman, Brisa Peña, Ayman J Oweida, Sara Zakem, Cheryl Meguid, Michael W Knitz, Laurel Darragh, Thomas E Bickett, Jacob Gadwa, Luisa Mestroni, Matthew R G Taylor, Kimberly R Jordan, Peter Dempsey, M Scott Lucia, Martin D McCarter, Marco Del Chiaro, Wells A Messersmith, Richard D Schulick, Karyn A Goodman, Michael J. Gough, Casey S Greene, James C Costello, Antonio Galvao Neto, David Lagares, Kirk C Hansen, Adrie Van Bokhoven, and Sana D Karam
Regulation of MRE11A by UBQLN4 leads to cisplatin resistance in patients with esophageal squamous cell carcinoma., Tomohiro Murakami, Yoshiaki Shoji, Tomohiko Nishi, Shu-Ching Chang, Ron D Jachimowicz, Sojun Hoshimoto, Shigeshi Ono, Yosef Shiloh, Hiroya Takeuchi, Yuko Kitagawa, Dave Hoon, and Matias Bustos
Impact of XPO1 mutations on survival outcomes in metastatic non-small cell lung cancer (NSCLC)., Misako Nagasaka, Mohammad Fahad B Asad, Mohammed Najeeb Al Hallak, Md Hafiz Uddin, Ammar Sukari, Yasmine Baca, Joanne Xiu, Dan Magee, Hirva Mamdani, Dipesh Uprety, Chul Kim, Bing Xia, Stephen V Liu, Jorge J Nieva, Gilberto Lopes, Gerold Bepler, Hossein Borghaei, Michael J Demeure, Luis E Raez, Patrick C Ma, Sonam Puri, W Michael Korn, and Asfar S Azmi
509 A first-in-human phase 1 study of NL-201 in patients with relapsed or refractory cancer, Aung Naing, Brendan Curti, and See full list of authors in comments
Collagenous Gastritis in Primary Selective IgM Deficiency: Transition to EBV+ Gastric Adenocarcinoma., Tejal Narsai, Houfen Su, David Braxton, and Sudhir Gupta
Proteogenomic Characterization of Highly Enriched Viable Leukemic Blasts in Acute Myeloid Leukemia: A SWOG Report, Jasmine Naru, John E Godwin, and See full list of authors in comments
Overall Survival Benefit with Tebentafusp in Metastatic Uveal Melanoma., Paul Nathan, Jessica C Hassel, Piotr Rutkowski, Jean-Francois Baurain, Marcus O Butler, Max Schlaak, Ryan J Sullivan, Sebastian Ochsenreither, Reinhard Dummer, John M Kirkwood, Anthony M Joshua, Joseph J Sacco, Alexander N Shoushtari, Marlana Orloff, Josep M Piulats, Mohammed Milhem, April K S Salama, Brendan Curti, Lev Demidov, Lauris Gastaud, Cornelia Mauch, Melinda Yushak, Richard D Carvajal, Omid Hamid, Shaad E Abdullah, Chris Holland, Howard Goodall, Sophie Piperno-Neumann, and IMCgp100-202 Investigators
Compassionate Healthcare, Krista Nelson
Driving Oncology Forward, Krista Nelson
Frequency of Sarcopenia, Sarcopenic Obesity, and Changes in Physical Function in Surgical Oncology Patients Referred for Prehabilitation., An Ngo-Huang, Aliea Herbert, Rhodora C Fontillas, Nathan H Parker, Roan Asumbrado, Naveen Garg, Seyedeh Dibaj, Diane D Liu, Amy H Ng, Ying Guo, Ki Y Shin, Matthew H G Katz, and Eduardo Bruera
Synthesis and Preclinical Validation of Novel Indole Derivatives as a GPR17 Agonist for Glioblastoma Treatment., Phung Nguyen, Phuong Doan, Tatu Rimpilainen, Saravanan Konda Mani, Akshaya Murugesan, Olli Yli-Harja, Nuno R Candeias, and Meenakshisundaram Kandhavelu
1665 - QuPath versus InForm: Digital image analysis of multiplex immunofluorescence (mIF) tumor-infiltrating lymphocyte (TIL) outcomes in an immunotherapy clinical trial, Benjamin Nikitin, Brie Chun, Isaac Kim, William L. Redmond, Katherine Sanchez, Zhaoyu Sun, Yaping Wu, and David B Page
Atezolizumab Plus Chemotherapy for First-Line Treatment of Nonsquamous NSCLC: Results From the Randomized Phase 3 IMpower132 Trial., Makoto Nishio, Fabrice Barlesi, Howard West, Simon Ball, Rodolfo Bordoni, Manuel Cobo, Pascale Dubray Longeras, Jerome Goldschmidt, Silvia Novello, Francisco Orlandi, Rachel E Sanborn, Zsuzsanna Szalai, Grigoriy Ursol, Diana Mendus, Lijia Wang, Xiaohui Wen, Mark McCleland, Tien Hoang, See Phan, and Mark A Socinski
Safety and efficacy of durvalumab with R-CHOP or R, Grzegorz S Nowakowski, Wolfgang Willenbacher, Richard Greil, Thomas S Larsen, Krish Patel, Ulrich Jäger, Robert F Manges, Lorenz Trümper, Hele Everaus, Nagesh Kalakonda, Peter Brown, Judit Meszaros Jørgensen, David Cunningham, Justine Dell'Aringa, Brian Fox, Neus Domper Rubio, Nurgul Kilavuz, Marie-Laure Casadebaig, Oliver Manzke, and Javier Munoz
Allogeneic Transplantation in Fit Older Adults Is Feasible and Encouragingly Efficacious. Post Remission Data from the Prospective ECOG-ACRIN (E2906) Clinical Study, Yishai Ofran, John E Godwin, and See full list of authors in comments
PRoBE the cloud toolkit: finding the best biomarkers of drug response within a breast cancer clinical trial., Nicholas O'Grady, David L Gibbs, Kawther Abdilleh, Adam Asare, Smita Asare, Sara Venters, Lamorna Brown-Swigart, Gillian L Hirst, Denise Wolf, Christina Yau, Laura J van 't Veer, Laura Esserman, and Amrita Basu
The TIME Trial® Network facilitates rapid clinical trial activation, patient screening, and enrollment in molecularly targeted trials, Stephanie O'Leary, Megan Shulman, Kevin Ritt, Meghan Degele, Ewelina Protomastro, Jennifer Clauson, Amy Franzen, Ian Churchill Anderson, Minal A. Barve, David N. Oubre, Victor Priego, Angela Saverimuthu, Francis Mark Senecal, Raju Kumar Vaddepally, Kimberly L. Blackwell, and Matthew M. Cooney
RaPiDS (GOG-3028): randomized Phase II study of balstilimab alone or in combination with zalifrelimab in cervical cancer., David M O'Malley, Leslie M Randall, Camille Gunderson Jackson, Robert L Coleman, John L Hays, Kathleen N Moore, R Wendel Naumann, Rodney P Rocconi, Brian M Slomovitz, Krishnansu S Tewari, Marek Ancukiewicz, Waldo Ortuzar Feliu, and Bradley J Monk
Breast MRI during Neoadjuvant Chemotherapy: Lack of Background Parenchymal Enhancement Suppression and Inferior Treatment Response., Natsuko Onishi, Wen Li, David C Newitt, Roy J Harnish, Fredrik Strand, Alex Anh-Tu Nguyen, Vignesh Amal Arasu, Jessica Gibbs, Ella F Jones, Lisa J Wilmes, John Kornak, Bonnie N Joe, Elissa R Price, Haydee Ojeda-Fournier, Mohammad Eghtedari, Kathryn W Zamora, Stefanie Woodard, Heidi R Umphrey, Michael T Nelson, An L Church, Patrick J Bolan, Theresa Kuritza, Kathleen Ward, Kevin Morley, Dulcy Wolverton, Kelly Fountain, Dan Lopez Paniagua, Lara Hardesty, Kathleen R Brandt, Elizabeth S McDonald, Mark Rosen, Despina Kontos, Hiroyuki Abe, Deepa Sheth, Erin Crane, Charlotte Dillis, Pulin Sheth, Linda Hovanessian-Larsen, Dae Hee Bang, Bruce Porter, Karen Y Oh, Neda Jafarian, Luminita A Tudorica, Bethany Niell, Jennifer Drukteinis, Mary S Newell, Marina E Giurescu, Elise Berman, Constance D Lehman, Savannah C Partridge, Kimberly A Fitzpatrick, Marisa H Borders, Wei Tse Yang, Basak Dogan, Sally Hayward Goudreau, Thomas Chenevert, Christina Yau, Angela DeMichele, Donald A Berry, Laura J Esserman, and Nola M Hylton
Radiotherapy Versus Inguinofemoral Lymphadenectomy as Treatment for Vulvar Cancer Patients With Micrometastases in the Sentinel Node: Results of GROINSS-V II., Maaike H M Oonk, Brian Slomovitz, Peter J W Baldwin, Helena C van Doorn, Jacobus van der Velden, Joanne A de Hullu, Katja N Gaarenstroom, Brigitte F M Slangen, Ignace Vergote, Mats Brännström, Eleonora B L van Dorst, Willemien J van Driel, Ralph H Hermans, David Nunns, Martin Widschwendter, David Nugent, Cathrine M Holland, Aarti Sharma, Paul A DiSilvestro, Robert Mannel, Dorry Boll, David Cibula, Al Covens, Diane Provencher, Ingo B Runnebaum, David Luesley, Patricia Ellis, Timothy J Duncan, Ming Y Tjiong, Derek J Cruickshank, Preben Kjølhede, Charles F Levenback, Jiri Bouda, Katharina E Kieser, Connie Palle, Nicola M Spirtos, David M O'Malley, Mario M Leitao, Melissa A Geller, Kalyan Dhar, Viren Asher, Karl Tamussino, Daniel H Tobias, Christer Borgfeldt, Jayanthi S Lea, Jo Bailey, Margareta Lood, Brynhildur Eyjolfsdottir, Stephen Attard-Montalto, Krishnansu S Tewari, Ranjit Manchanda, Pernille T Jensen, Par Persson, Linda Van Le, Hein Putter, Geertruida H de Bock, Bradley J Monk, Carien L Creutzberg, and Ate G J van der Zee
ASO Author Reflections: Molecular Testing in Breast Cancer: Is Core Biopsy Equivalent to Surgical Specimen?, Javier I Orozco and Janie Grumley
Is the 21-Gene Recurrence Score on Core Needle Biopsy Equivalent to Surgical Specimen in Early-Stage Breast Cancer? A Comparison of Gene Expression Between Paired Core Needle Biopsy and Surgical Specimens., Javier I J Orozco, Shu-Ching Chang, Chikako Matsuba, Miquel Ensenyat-Mendez, Gary L Grunkemeier, Diego M Marzese, and Janie G Grumley
ASO Visual Abstract: Is the 21-Gene Recurrence Score on Core Needle Biopsy Equivalent to Surgical Specimen in Early-Stage Breast Cancer? : A Comparison of Gene Expression Between Paired Core Needle Biopsy and Surgical Specimens., Javier I J Orozco, Shu-Ching Chang, Chikako Matsuba, Miquel Ensenyat-Mendez, Gary L Grunkemeier, Diego M Marzese, and Janie G Grumley
Associations between complete remission and 2- to 3-year survival following 7 + 3 induction for acute myeloid leukemia., Megan Othus, Guillermo Garcia-Manero, John E Godwin, James Weick, Derek Stirewalt, Frederick Appelbaum, Harry Erba, and Elihu Estey
Advances in Immunotherapy, David B Page
Teaming up to Finish Triple-Negative Breast Cancer, David B Page
399 A phase II study of nivolumab, ipilimumab, plus androgen receptor blockade with bicalutamide to enhance thymic T-cell production and immunotherapy response in metastatic breast cancer, David B Page, Krystle Collins, Brie Chun, Zhaoyu Sun, Yoshinobu Koguchi, William L. Redmond, Maritza Martel, Yaping Wu, Nikki Moxon, Staci Mellinger, Walter Urba, Ayca Gucalp, and Tiffany Traina
A phase II study of nivolumab, ipilimumab, plus androgen receptor blockade with bicalutamide to enhance thymic T-cell production and immunotherapy response in metastatic breast cancer, David B Page, Krystle Collins, Brie Chun, Zhaoyu Sun, Yoshinobu Koguchi, William D Ryan, Maritza Martel, Yaping Wu, Nikki Moxon, Staci Mellinger, Walter Urba, Ayca Gucalp, and Tiffany A. Traina
OT1-18-04. A phase II study of dual immune checkpoint blockade (ICB) plus bicalutamide to enhance thymic T-cell production and immunotherapy response in metastatic breast cancer (MBC), David B Page, Krystle L. Collins, Brie Chun, Zhaoyu Sun, William L. Redmond, Maritza Martel, Yaping Wu, Nikki Moxon, Staci Mellinger, Walter Urba, Tiffany Traina, and Ayca Gucalp
