Providence research from Southern California locations.

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Submissions from 2022

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778 Botensilimab, a novel innate/adaptive immune activator, plus or minus balstilimab (anti-PD-1) in “cold” and I-O refractory metastatic solid tumors, Breelyn Wilky, Kim Margolin, Rachel E Sanborn, Steven O'Day, and See full list of authors in comments

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Surgical approach to pediatric mediastinal masses based on imaging characteristics., Stephanie Young, R Luke Rettig, Ian V Hutchinson, Michael G Sutcliffe, and Roman M Sydorak

Submissions from 2021

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Coronary Sinus Lead Placement in Patients With Coronary Sinus Ostial Atresia: An Innovative Approach., Ata Bajwa, Jashdeep Dhoot, and Sanjaya Gupta

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Creating Clinically Relevant Aneurysm Sizes in the Rabbit Surgical Elastase Model., Brooke L Belanger, Michael B Avery, Arindom Sen, Muneer Eesa, and Alim P Mitha

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The miR-181a-SFRP4 axis regulates Wnt activation to drive stemness and platinum resistance in ovarian cancer., Anil Belur Nagaraj, Matthew Knarr, Sreeja Sekhar, R Shae Connor, Peronne Joseph, Olga Kovalenko, Alexis Fleming, Arshia Surti, Elmar Nurmemmedov, Luca Beltrame, Sergio Marchini, Michael Kahn, and Analisa DiFeo

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COVID-19 in Patients With Pre-existing Neurologic Disorders: Clinical Course and Outcomes (2608), Svetlana Blitshteyn, Akanksha Sharma, and See full list of authors in comments

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DNA Damage Response in Glioblastoma: Mechanism for Treatment Resistance and Emerging Therapeutic Strategies., Alipi Bonm and Santosh Kesari

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Marizomib alone or in combination with bevacizumab in patients with recurrent glioblastoma: Phase I/II clinical trial data., Daniela A Bota, Warren Mason, Santosh Kesari, Rajiv Magge, Benjamin Winograd, Ileana Elias, Steven D Reich, Nancy Levin, Mohit Trikha, and Annick Desjardins

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Cost-effectiveness of Hypertension Treatment by Pharmacists in Black Barbershops., Kelsey B Bryant, Andrew E Moran, Dhruv S Kazi, Yiyi Zhang, Joanne Penko, Natalia Ruiz-Negrón, Pamela Coxson, Ciantel A Blyler, Kathleen Lynch, Laura P Cohen, Gabriel S Tajeu, Valy Fontil, Norma B Moy, Joseph E Ebinger, Florian Rader, Kirsten Bibbins-Domingo, and Brandon K Bellows

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Nonpeptidic, Polo-Box Domain-Targeted Inhibitors of PLK1 Block Kinase Activity, Induce Its Degradation and Target-Resistant Cells., Danda Chapagai, Gurusankar Ramamoorthy, Jessy Varghese, Elmar Nurmemmedov, Campbell McInnes, and Michael D Wyatt

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Primary Chemoablation of Low-Grade Intermediate-Risk Non-Muscle-Invasive Bladder Cancer Using UGN-102, A Mitomycin-Containing Reverse Thermal Gel (Optima II): A Phase 2b, Open-Label, Single-Arm Trial., K Kent Chevli, Neal D Shore, Andrew Trainer, Angela B Smith, Daniel Saltzstein, Yaron Ehrlich, Jay D Raman, Boris Friedman, Richard D'Anna, David Morris, Brian Hu, Mark Tyson, Alexander Sankin, Max Kates, Jennifer Linehan, Douglas Scherr, Steven Kester, Michael Verni, Karim Chamie, Lawrence Karsh, Arnold Cinman, Andrew Meads, Soumi Lahiri, Madlen Malinowski, Nimrod Gabai, Sunil Raju, Mark Schoenberg, Elyse Seltzer, and William C Huang

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Undifferentiated Carcinoma With Osteoclast-Like Giant Cells of the Pancreas Discovered on Positron Emission Tomography Performed for Lymphoma Staging., Wade O Christopher, Trevan D Fischer, and Anton J Bilchik

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SNO 2020 diversity survey: defining demographics, racial biases, career success metrics and a path forward for the field of neuro-oncology., Ugonma N Chukwueke, Elizabeth Vera, Alvina Acquaye, Shawn L Hervey-Jumper, Yazmin Odia, Laura J Klesse, Erin Dunbar, Akanksha Sharma, Ekokobe Fonkem, Alissa A Thomas, Tamra E Werbowetski-Ogilvie, Sandra Camelo-Piragua, Na Tosha N Gatson, Macarena I de la Fuente, Terri S Armstrong, Alyx B Porter, and Sadhana Jackson

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Lung epithelial and endothelial damage, loss of tissue repair, inhibition of fibrinolysis, and cellular senescence in fatal COVID-19., Felice D'Agnillo, Kathie-Anne Walters, Yongli Xiao, Zong-Mei Sheng, Kelsey Scherler, Jaekeun Park, Sebastian Gygli, Luz Angela Rosas, Kaitlyn Sadtler, Heather Kalish, Charles A Blatti, Ruoqing Zhu, Lisa Gatzke, Colleen Bushell, Matthew J Memoli, Steven O'Day, Trevan Fischer, Terese C Hammond, Raymond C Lee, J Christian Cash, Matthew E Powers, Grant E O'Keefe, Kelly J Butnor, Amy V Rapkiewicz, William D Travis, Scott P Layne, John C Kash, and Jeffery K Taubenberger

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Correction to: Gliosarcoma vs. glioblastoma: a retrospective case series using molecular profiling., Christopher Dardis, David Donner, Nader Sanai, Joanne Xiu, Sandeep Mittal, Sharon K Michelhaugh, Manjari Pandey, Santosh Kesari, Amy B Heimberger, Zoran Gatalica, Michael W Korn, Ashley L Sumrall, and Surasak Phuphanich

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Gliosarcoma vs. glioblastoma: a retrospective case series using molecular profiling., Christopher Dardis, David Donner, Nader Sanai, Joanne Xiu, Sandeep Mittal, Sharon K Michelhaugh, Manjari Pandey, Santosh Kesari, Amy B Heimberger, Zoran Gatalica, Michael W Korn, Ashley L Sumrall, and Surasak Phuphanich

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Facebook Live: COVID-19 Long Haulers and facts about the vaccines, Howard Davis and Laura Ramos

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Effects of Pyridostigmine on Esophageal and Pharyngeal Motility in Dysphagic Patients Undergoing High-Resolution Manometry., Shumon I Dhar, Nogah Nativ-Zeltzer, Omid B Mehdizadeh, Apoorva T Ramaswamy, Yuval Nachalon, and Peter C Belafsky

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Remdesivir and Mortality in Patients with COVID-19., George A Diaz, Alyssa B Christensen, Tobias Pusch, Delaney Goulet, Shu-Ching Chang, Gary L Grunkemeier, Paul A McKelvey, Ari Robicsek, Tom French, Guilford T Parsons, Glenn Doherty, Charles Laurenson, Ryan Roper, Jennifer Hadlock, Cameron J Cover, Brent Footer, Philip Robinson, Mary Micikas, Jennifer E Marfori, Charlotte Cronenweth, Yogavedya Mukkamala, Jamie Mackiewicz, Ekra Rai, Martha Dickinson Matson, Jodie Davila, Justin Rueda, Reda Tipton, Heather Algren, Brittney C Ward, Stephen Malkoski, Tyler Gluckman, Gregory B Tallman, Henry Arguinchona, Terese C Hammond, Steven Standaert, Joshua Christensen, Jose F Echaiz, Robert Choi, Daniel McClung, Albert Pacifico, Martin Fee, Farjad Sarafian, William R Berrington, and Jason D Goldman

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Disparities in Amputation Rates for Non-metastatic Extremity Soft Tissue Sarcomas and the Impact on Survival., Joshua C Dilday, Daniel W Nelson, Trevan D Fischer, and Melanie Goldfarb

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Neoadjuvant talimogene laherparepvec plus surgery versus surgery alone for resectable stage IIIB-IVM1a melanoma: a randomized, open-label, phase 2 trial., R Dummer, D E Gyorki, J Hyngstrom, A C Berger, R Conry, L Demidov, A Sharma, S A Treichel, H Radcliffe, K S Gorski, A Anderson, E Chan, M Faries, and M I Ross

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Modified RANO, Immunotherapy RANO, and Standard RANO Response to Convection-Enhanced Delivery of IL4R-Targeted Immunotoxin MDNA55 in Recurrent Glioblastoma., Benjamin M Ellingson, John Sampson, Achal Singh Achrol, Manish K Aghi, Krystof Bankiewicz, Chencai Wang, Martin Bexon, Steven Brem, Andrew Brenner, Sajeel Chowdhary, John R Floyd, Seunggu Han, Santosh Kesari, Dina Randazzo, Michael A Vogelbaum, Frank Vrionis, Miroslaw Zabek, Nicholas Butowski, Melissa Coello, Nina Merchant, and Fahar Merchant

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Cryopreserved placental tissue allograft accelerates time to continence following robot-assisted radical prostatectomy., Peter A Elliott, Stephanie Hsiang, Ramkishen Narayanan, James Bierylo, Shu-Ching Chang, Przemyslaw Twardowski, and Timothy G Wilson

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Current Triple-Negative Breast Cancer Subtypes: Dissecting the Most Aggressive Form of Breast Cancer., Miquel Ensenyat-Mendez, Pere Llinàs-Arias, Javier I J Orozco, Sandra Íñiguez-Muñoz, Matthew P Salomon, Borja Sesé, Maggie L DiNome, and Diego M Marzese

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A phase I study of the WT2725 dosing emulsion in patients with advanced malignancies., Siqing Fu, David E Piccioni, Hongtao Liu, Rimas V Lukas, Santosh Kesari, Dawit Aregawi, David S Hong, Kenichiro Yamaguchi, Kate Whicher, Yi Zhang, Yu-Luan Chen, Nagaraju Poola, John Eddy, and David Blum

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Assessment of Discrepancies Between Follow-up Infarct Volume and 90-Day Outcomes Among Patients With Ischemic Stroke Who Received Endovascular Therapy., Aravind Ganesh, Johanna M Ospel, Bijoy K Menon, Andrew M Demchuk, Ryan A McTaggart, Raul G Nogueira, Alexandre Y Poppe, Mohammed A Almekhlafi, Ricardo A Hanel, Götz Thomalla, Staffan Holmin, Volker Puetz, Brian A van Adel, Jason Tarpley, Michael Tymianski, Michael D Hill, Mayank Goyal, and ESCAPE-NA1 Trial Investigators

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The effect of specific binding proteins on immunoassay measurements of total and free thyroid hormones and cortisol., Anastasia Gant Kanegusuku, Katherine A Araque, Hung Nguyen, Bin Wei, Saman Hosseini, and Steven J Soldin

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"Young children are not the same as adolescents when it comes to treating thyroid cancer"., Melanie Goldfarb, Emily Christison-Lagay, Jeff Rastatter, and Jonathan Wasserman

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Microtia Reconstruction and Erector Spinae Block in Children: A Case Series With Chart Review., Gabriel Gomez, Beth Osterbauer, Robert Nguyen, Choo Phei Wee, Amit Kochhar, Tymon Tai, Carl Yuan-Feng Lo, Sang Le, Eugene Kim, and Shiu-Yi Chen

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National Network Column Post, Carrie Grinstead

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Analysis of an obstetrics point-of-care ultrasound training program for healthcare practitioners in Zanzibar, Tanzania., Elizabeth A Hall, Danielle Matilsky, Rachel Zang, Naomasa Hase, Ali Habibu Ali, Patricia C Henwood, and Anthony J Dean

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Hepatic Plexus Nerve Block for Microwave Ablation of Hepatic Tumors., Frank Hao, Navid Eghbalieh, Alexandra So, and Edward Wolfgang Lee

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Correction to: Physician-directed genetic screening to evaluate personal risk for medically actionable disorders: a large multi-center cohort study., Eden V Haverfield, Edward D Esplin, Sienna J Aguilar, Kathryn E Hatchell, Kelly E Ormond, Andrea Hanson-Kahn, Paldeep S Atwal, Sarah Macklin-Mantia, Stephanie Hines, Caron W-M Sak, Steven Tucker, Steven B Bleyl, Peter J Hulick, Ora K Gordon, Lea Velsher, Jessica Y J Gu, Scott M Weissman, Teresa Kruisselbrink, Christopher Abel, Michele Kettles, Anne Slavotinek, Bryce A Mendelsohn, Robert C Green, Swaroop Aradhya, and Robert L Nussbaum

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Physician-directed genetic screening to evaluate personal risk for medically actionable disorders: a large multi-center cohort study., Eden V Haverfield, Edward D Esplin, Sienna J Aguilar, Kathryn E Hatchell, Kelly E Ormond, Andrea Hanson-Kahn, Paldeep S Atwal, Sarah Macklin-Mantia, Stephanie Hines, Caron W-M Sak, Steven Tucker, Steven B Bleyl, Peter J Hulick, Ora K Gordon, Lea Velsher, Jessica Y J Gu, Scott M Weissman, Teresa Kruisselbrink, Christopher Abel, Michele Kettles, Anne Slavotinek, Bryce A Mendelsohn, Robert C Green, Swaroop Aradhya, and Robert L Nussbaum

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An Analysis of Nigerian Igbo Women's Petitions to U.S. Missionary Nurses in 1965., Martha E F Highfield

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The Impact of the Implementation of Code-Blue Nurse Champions for Cardiac Arrest, Beverly Holland and Sherri Mendelson

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EpiMap: Fine-tuning integrative epigenomics maps to understand complex human regulatory genomic circuitry., Dave S B Hoon, Negin Rahimzadeh, and Matias A Bustos

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Plexin-B2 orchestrates collective stem cell dynamics via actomyosin contractility, cytoskeletal tension and adhesion., Chrystian Junqueira Alves, Rafael Dariolli, Jonathan Haydak, Sangjo Kang, Theodore Hannah, Robert J Wiener, Stefanie DeFronzo, Rut Tejero, Gabriele L Gusella, Aarthi Ramakrishnan, Rodrigo Alves Dias, Alexandre Wojcinski, Santosh Kesari, Li Shen, Eric A Sobie, José Paulo Rodrigues Furtado de Mendonça, Evren U Azeloglu, Hongyan Zou, and Roland H Friedel

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Primary Outcome Evaluation of a Next-Generation Left Atrial Appendage Closure Device: Results From the PINNACLE FLX Trial., Saibal Kar, Shephal K Doshi, Ashish Sadhu, Rodney Horton, Jose Osorio, Christopher Ellis, James Stone, Manish Shah, Srinivas R Dukkipati, Stuart Adler, Devi G Nair, Jamie Kim, Oussama Wazni, Mathew J Price, Federico M Asch, David R Holmes, Robert D Shipley, Nicole T Gordon, Dominic J Allocco, Vivek Y Reddy, and PINNACLE FLX Investigators

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Scaling Up Pharmacist-Led Blood Pressure Control Programs in Black Barbershops: Projected Population Health Impact and Value., Dhruv S Kazi, Pengxiao C Wei, Joanne Penko, Brandon K Bellows, Pamela Coxson, Kelsey B Bryant, Valy Fontil, Ciantel A Blyler, Courtney Lyles, Kathleen Lynch, Joseph Ebinger, Yiyi Zhang, Gabriel S Tajeu, Ross Boylan, Mark J Pletcher, Florian Rader, Andrew E Moran, and Kirsten Bibbins-Domingo

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Vitamin D deficiency exacerbates UV/endorphin and opioid addiction., Lajos V Kemény, Kathleen C Robinson, Andrea L Hermann, Deena M Walker, Susan Regan, Yik Weng Yew, Yi Chun Lai, Nicholas Theodosakis, Phillip D Rivera, Weihua Ding, Liuyue Yang, Tobias Beyer, Yong-Hwee E Loh, Jennifer A Lo, Anita A J van der Sande, William Sarnie, David Kotler, Jennifer J Hsiao, Mack Y Su, Shinichiro Kato, Joseph Kotler, Staci D Bilbo, Vanita Chopra, Matthew P Salomon, Shiqian Shen, Dave S B Hoon, Maryam M Asgari, Sarah E Wakeman, Eric J Nestler, and David E Fisher

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Mesenchymal stem cells in the treatment of severe COVID-19., Santosh Kesari, Gregory C Kasper, Lev Verkh, Terese C Hammond, Marla L Matal, Jay W Hammerling, Nikolai Tankovich, Adrianus P Lim, Kevin H Zhao, Tiffany Juarez, Roberta E Redfern, Jaya M Gill, Natsuko Nomura, Audrey Hiemer, Annie Heng, and Jessica Shoemaker

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Correction to: Mesenchymal stem cells in the treatment of severe COVID-19., Santosh Kesari, Gregory C Kasper, Lev Verkh, Terese C Hammond, Marla L Matal, Jay W Hammerling, Nikolai Tankovich, Adrianus P Lim, Kevin H Zhao, Tiffany Juarez, Roberta E Redfern, Jaya Mini Gill, Natsuko Nomura, Audrey Hiemer, Annie Heng, and Jessica Shoemaker

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Response to: Is there any association between a delay in surgery and nodal positivity in the ER-negative Her2 negative breast cancer subgroups?, Adam Khader and Trevan Fischer

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A Hospital and Postdischarge Quality Improvement Intervention and Outcomes and Care for Patients With Heart Failure With Reduced Ejection Fraction., Daniel S Kim, Nhu Quyen Dau, and Harry Peled

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Orbital Surgical Guidelines-Clinical Evaluation., Howard Krauss

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An empirical antigen selection method identifies neoantigens that either elicit broad anti-tumor T cell responses or drive tumor growth., Hubert Lam, Lisa K McNeil, Hanna Starobinets, Victoria L DeVault, Roger B Cohen, Przemyslaw Twardowski, Melissa L Johnson, Maura L Gillison, Mark N Stein, Ulka N Vaishampayan, Arthur P DeCillis, James J Foti, Vijetha Vemulapalli, Emily Tjon, Kyle Ferber, Daniel B DeOliveira, Wendy Broom, Parul Agnihotri, Elizabeth M Jaffee, Kwok-Kin Wong, Charles G Drake, Pamela M Carroll, Thomas A Davis, and Jessica Baker Flechtner

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WNT Signaling as a Therapeutic Target for Glioblastoma., Michael Latour, Nam-Gu Her, Santosh Kesari, and Elmar Nurmemmedov

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Quiet Time to Increase Breastfeeding Rates and Enhance Women's Hospital Experiences in the Postpartum Period., Christen Lawrie, Martha E F Highfield, and Sherri Mendelson

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Integrated analysis of plasma and single immune cells uncovers metabolic changes in individuals with COVID-19., Jihoon W Lee, Yapeng Su, Priyanka Baloni, Daniel Chen, Ana Jimena Pavlovitch-Bedzyk, Dan Yuan, Venkata R Duvvuri, Rachel H Ng, Jongchan Choi, Jingyi Xie, Rongyu Zhang, Kim Murray, Sergey A Kornilov, Brett Smith, Andrew T Magis, Dave Hoon, Jennifer J Hadlock, Jason D Goldman, Nathan D Price, Raphael Gottardo, Mark M Davis, Leroy Hood, Philip D Greenberg, and James R Heath

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Beyond Sedlis-A novel histology-specific nomogram for predicting cervical cancer recurrence risk: An NRG/GOG ancillary analysis., Kimberly Levinson, Anna L Beavis, Christopher Purdy, Anne F Rositch, Akila Viswanathan, Aaron H Wolfson, Michael G Kelly, Krishnansu S Tewari, Leah McNally, Saketh R Guntupalli, Omar Ragab, Yi-Chun Lee, David S Miller, Warner K Huh, Kelly J Wilkinson, Nicola M Spirtos, Linda Van Le, Yovanni Casablanca, Laura L Holman, Steven E Waggoner, and Amanda N Fader

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Measurements of Functional Network Connectivity Using Resting State Arterial Spin Labeling During Neurosurgery., Thomas Lindner, Hajrullah Ahmeti, Michael Helle, Olav Jansen, Jens Fiehler, Lasse Dührsen, Michael Synowitz, Santosh Kesari, and Stephan Ulmer

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Epigenetic Regulation of Immunotherapy Response in Triple-Negative Breast Cancer., Pere Llinàs-Arias, Sandra Íñiguez-Muñoz, Kelly McCann, Leonie Voorwerk, Javier I J Orozco, Miquel Ensenyat-Mendez, Borja Sesé, Maggie L DiNome, and Diego M Marzese

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Characterization of outcomes and practices utilized in the management of internal carotid artery injury not requiring definitive endovascular management., Nyall R London, Abdulaziz AlQahtani, Siani Barbosa, Paolo Castelnuovo, Davide Locatelli, Aldo Stamm, Aaron A Cohen-Gadol, Hussam Elbosraty, Roy Casiano, Jacques Morcos, Ernesto Pasquini, Georgio Frank, Diego Mazzatenta, Garni Barkhoudarian, Chester Griffiths, Daniel Kelly, Christos Georgalas, Trichy N Janakiram, Piero Nicolai, Daniel M Prevedello, and Ricardo L Carrau

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Standard-Dose Pembrolizumab Plus Alternate-Dose Ipilimumab in Advanced Melanoma: KEYNOTE-029 Cohort 1C, a Phase 2 Randomized Study of Two Dosing Schedules., Georgina V Long, Caroline Robert, Marcus O Butler, Felix Couture, Matteo S Carlino, Steven O'Day, Victoria Atkinson, Jonathan S Cebon, Michael P Brown, Stephane Dalle, Andrew G Hill, Geoffrey T Gibney, Steven McCune, Alexander M Menzies, Cuizhen Niu, Nageatte Ibrahim, Blanca Homet Moreno, and Adi Diab

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Facebook Live: Spanish language Town Hall on the COVID-19 vaccine (Únete a una reunión comunitaria virtual sobre la vacuna para el COVID-19.), Ana Lopez, Jazmyn Jasso, Carlos Rodriguez, and Mary Ann Walker Aguirre

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Beyond the Chemotherapy Certificate: Building a Knowledge Base Virtually for Oncology Nursing Practice Across a Health System., Julianne Luttrell, Sarah Sumner, Emy-Lee Marie Anglo Ricafrente, and Marlon G Saria

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Streamlining brain tumor surgery care during the COVID-19 pandemic: A case-control study., Regin Jay Mallari, Michael B Avery, Alex Corlin, Amalia Eisenberg, Terese C Hammond, Neil A Martin, Garni Barkhoudarian, and Daniel F Kelly

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Diagnostic pitfalls in Cushing's disease impacting surgical remission rates; test thresholds and lessons learned in 105 patients., Regin Jay Mallari, Jai Deep Thakur, Garni Barkhoudarian, Amy Eisenberg, Amanda Rodriguez, Sarah Rettinger, Pejman Cohan, Lynnette Nieman, and Daniel F Kelly

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Endoscopic Endonasal and Supraorbital Removal of Tuberculum Sellae Meningiomas: Anatomic Guides and Operative Nuances for Keyhole Approach Selection., Regin Jay Mallari, Jai Deep Thakur, John H Rhee, Amalia Eisenberg, Howard Krauss, Chester Griffiths, Walavan Sivakumar, Garni Barkhoudarian, and Daniel F Kelly

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Durability of Response to Primary Chemoablation of Low-Grade Upper Tract Urothelial Carcinoma Using UGN-101, a Mitomycin-Containing Reverse Thermal Gel: OLYMPUS Trial Final Report., Surena F Matin, Phillip M Pierorazio, Nir Kleinmann, John L Gore, Ahmad Shabsigh, Brian Hu, Karim Chamie, Guilherme Godoy, Scott G Hubosky, Marcelino Rivera, Michael O'Donnell, Marcus Quek, Jay D Raman, John J Knoedler, Douglas Scherr, Christopher Weight, Alon Weizer, Michael Woods, Hristos Kaimakliotis, Angela B Smith, Jennifer M Linehan, Jonathan Coleman, Mitchell R Humphreys, Raymond Pak, David Lifshitz, Michael Verni, Ifat Klein, Marina Konorty, Dalit Strauss-Ayali, Gil Hakim, Elyse Seltzer, Mark Schoenberg, and Seth P Lerner

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Vertebral Augmentation of Cancer-Related Spinal Compression Fractures: A Systematic Review and Meta-Analysis., Ryan Mattie, Nick Brar, Jennifer T Tram, Zachary L McCormick, Douglas P Beall, Andrew Fox, and Mikhail Saltychev

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A Microcosm of Disparities in Breast Cancer: Comparison Between a Private Hospital and a Safety-Net County Hospital Within Los Angeles County., Natalie C McClintock, Reed I Ayabe, Ruben D Salas Parra, Amy H Kaji, Javier I Orozco, Diego M Marzese, Estela Samuels, Stacey L Stern, Christine Dauphine, and Junko J Ozao-Choy

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A systems-biology clinical trial of a personalized multimodal lifestyle intervention for early Alzheimer's disease., Sarah C McEwen, David A Merrill, Jennifer Bramen, Verna Porter, Stella Panos, Scott Kaiser, John Hodes, Aarthi Ganapathi, Lesley Bell, Tess Bookheimer, Ryan Glatt, Molly Rapozo, Mary Kay Ross, Nathan D Price, Daniel Kelly, Cory C Funk, Leroy Hood, and Jared C Roach

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Quantitative MRI Differences Between Early versus Late Onset Alzheimer's Disease., Somayeh Meysami, Cyrus A Raji, David A Merrill, Verna R Porter, and Mario F Mendez

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Regulation of MRE11A by UBQLN4 leads to cisplatin resistance in patients with esophageal squamous cell carcinoma., Tomohiro Murakami, Yoshiaki Shoji, Tomohiko Nishi, Shu-Ching Chang, Ron D Jachimowicz, Sojun Hoshimoto, Shigeshi Ono, Yosef Shiloh, Hiroya Takeuchi, Yuko Kitagawa, Dave Hoon, and Matias Bustos

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Unconscious Bias and Self-Care:: Key Components of an Integrated, Comprehensive Health Care System Nurse Manager Leadership Development Program, LeAnn Ogilvie, Troy Larkin, and Jan L. Keller-Unger

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Perioperative outcomes in a nationwide sample of patients undergoing surgical treatment of ovarian endometriomas., Megan S Orlando, Meng Yao, Olivia H Chang, Ernie Shippey, Tawnya Bosko, Lauren A Cadish, Tommaso Falcone, and Rosanne M Kho

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A Review of Persistent Post-COVID Syndrome (PPCS)., Bryan Oronsky, Christopher Larson, Terese C Hammond, Arnold Oronsky, Santosh Kesari, Michelle Lybeck, and Tony R Reid

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ASO Author Reflections: Molecular Testing in Breast Cancer: Is Core Biopsy Equivalent to Surgical Specimen?, Javier I Orozco and Janie Grumley

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Is the 21-Gene Recurrence Score on Core Needle Biopsy Equivalent to Surgical Specimen in Early-Stage Breast Cancer? A Comparison of Gene Expression Between Paired Core Needle Biopsy and Surgical Specimens., Javier I J Orozco, Shu-Ching Chang, Chikako Matsuba, Miquel Ensenyat-Mendez, Gary L Grunkemeier, Diego M Marzese, and Janie G Grumley

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ASO Visual Abstract: Is the 21-Gene Recurrence Score on Core Needle Biopsy Equivalent to Surgical Specimen in Early-Stage Breast Cancer? : A Comparison of Gene Expression Between Paired Core Needle Biopsy and Surgical Specimens., Javier I J Orozco, Shu-Ching Chang, Chikako Matsuba, Miquel Ensenyat-Mendez, Gary L Grunkemeier, Diego M Marzese, and Janie G Grumley

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Abstract P77: Acute Stroke Trends and Outcomes During the COVID-19 Pandemic in a Multi-System Hospital System in the Western US, Renee Ovando, Natalie Swearingen, Tamela Stuchiner, Leslie Corless, Crystal Ann Moreno, John Zurasky, Jason Tarpley, Radoslav Raychev, and Elizabeth Baraban

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Eating Disorders: Identification and Management in General Medical and Psychiatric Settings., Rebecca A Owens, Evelyn Attia, Joyce J Fitzpatrick, Kathryn Phillips, and Stephanie Nolan

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COVID-19 Impact on Acute Ischemic Stroke Treatment at 9 Comprehensive Stroke Centers across Los Angeles., M Maximillian Padrick, Navdeep Sangha, Laurie Paletz, James Mirocha, Sonia Figueroa, Vicki Manoukian, Konrad Schlick, Patrick D Lyden, David S Liebeskind, Fiona K Chatfield, Jason W Tarpley, Adrian Burgos, Matthew Tenser, Denise Gaffney, Marco A Pech, Edward Nazareth, Robert Jackson, Helaine Kauffman, Lisa Arnold, Jennifer Cox, Treasure Joyce, Catrice Nakamura, Darcie Fitzgerald, Kyle Ogami, Nili Steiner, Nicole Wolber, Betty Robertson, Rachel Izzo, Stefanie Gorski, Heather Manuel, Krystal Valdez, Liliana Reyes, Latisha K Sharma, and Shlee S Song

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A Randomized Phase II Study of Androgen Deprivation Therapy with or without Palbociclib in RB-positive Metastatic Hormone Sensitive Prostate Cancer (mHSPC)., Phillip L Palmbos, Stephanie Daignault-Newton, Scott A Tomlins, Neeraj Agarwal, Przemyslaw Twardowski, Alicia K Morgans, William K Kelly, Vivek K Arora, Emmanuel S Antonarakis, Javed Siddiqui, Jon Jacobson, Mathew S Davenport, Dan R Robinson, Arul M Chinnaiyan, Karen E Knudsen, and Maha Hussain

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A Systems Approach to Brain Tumor Treatment., James H Park, Adrian Lopez Garcia de Lomana, Diego M Marzese, Tiffany Juarez, Abdullah Feroze, Parvinder Hothi, Charles Cobbs, Anoop P Patel, Santosh Kesari, Sui Huang, and Nitin S Baliga

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Perioperative dual antiplatelet therapy for patients undergoing spine surgery soon after drug eluting stent placement., Sophie M Peeters, Daniel Nagasawa, Bilwaj Gaonkar, Tianyi Niu, Alexander Tucker, Mark Attiah, Diana Babayan, Natalie Moreland, Isaac Yang, Marcela Calfon Press, and Luke Macyszyn

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Modify Centers for Medicare & Medicaid Services' Sepsis Core Measure (SEP-1) Now to Optimize Care for COVID-19., Harry Peled, Nhu Quyen Dau, and Shelley Schoepflin Sanders

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Operating costs, fiscal impact, value analysis and guidance for the routine use of robotic technology in abdominal surgical procedures., Philippe J Quilici, Harry Wolberg, and Nathaniel McConnell

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Phase II study of the histone deacetylase inhibitor vorinostat (Suberoylanilide Hydroxamic Acid; SAHA) in recurrent or metastatic transitional cell carcinoma of the urothelium - an NCI-CTEP sponsored: California Cancer Consortium trial, NCI 6879., David I Quinn, Denice D Tsao-Wei, Przemyslaw Twardowski, Ana M Aparicio, Paul Frankel, Gurkamal Chatta, John J Wright, Susan G Groshen, Stella Khoo, Heinz-Josef Lenz, Primo N Lara, David R Gandara, and Edward Newman

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Correction to: Clinical feasibility of umbilical cord tissue-derived mesenchymal stem cells in the treatment of multiple sclerosis., Neil H Riordan, Isabela Morales, Giselle Fernández, Nicole Allen, Neal E Fearnot, Michael E Leckrone, Dedra Jones Markovich, Darla Mansfield, Dorita Avila, Amit N Patel, Santosh Kesari, and Jorge Paz Rodriguez

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398 neoIRX: a phase II trial of locoregional cytokine therapy to promote immunologic priming and clinical response to neoadjuvant pembrolizumab plus chemotherapy in triple negative breast cancer (TNBC), Katherine Sanchez, Alison Conlin, Parvin Peddi, Sasha Stanton, Janet Ruzich, Kelly S Perlewitz, Yaping Wu, Nikki Moxon, Staci Mellinger, Zhaoyu Sun, William L. Redmond, and David B Page

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OT1-18-03. The neoIRX trial:locoregional cytokine therapy to promote immunologic priming and enhanced response to neoadjuvant pembrolizumab plus chemotherapy in triple negative breast cancer (TNBC), Katherine Sanchez, Alison Conlin, Parvin Peddi, Sasha Stanton, Janet Ruzich, Kelly S Perlewitz, Yaping Wu, Nikki Moxon, Staci Mellinger, Zhaoyu Sun, William L. Redmond, and David B Page

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Increased Intracranial Pressure: The Use of an Individualized Ladder Approach., Marlon G Saria and Santosh Kesari

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Phase I trial of intranasal NEO100, highly purified perillyl alcohol, in adult patients with recurrent glioblastoma., Axel H Schönthal, David M Peereboom, Naveed Wagle, Rose Lai, Anna J Mathew, Kyle M Hurth, Vincent F Simmon, Steven P Howard, Lynne P Taylor, Frances Chow, Clovis O da Fonseca, and Thomas C Chen

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Ethical Aspects of Artificially Administered Nutrition and Hydration: An ASPEN Position Paper., Denise Baird Schwartz, Albert Barrocas, Maria Giuseppina Annetta, Kathleen Stratton, Carol McGinnis, Gil Hardy, Theodoric Wong, Diego Arenas, Mary Pat Turon-Findley, Rubén Gustavo Kliger, Kelly Green Corkins, Jay Mirtallo, Teruyoshi Amagai, and Peggi Guenter

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Influence of Socioeconomic Status on Incident Medical Conditions in Two-Year Survivors of Adolescent or Young Adult Differentiated Thyroid Cancer., Thomas J Semrad, Qian Li, Melanie Goldfarb, Alison Semrad, Michael Campbell, D Gregory Farwell, and Theresa H M Keegan

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Top Ten Tips Palliative Care Clinicians Should Know About Seizures at the End of Life., Akanksha Sharma, Jessica M Besbris, Neha M Kramer, Farrah N Daly, Divya Singhal, Christopher A Jones, and Ambereen K Mehta

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How much time do we have? Longitudinal perception of prognosis in newly-diagnosed high grade glioma patients and caregivers compared to clinicians., Akanksha Sharma, Briant Fruth, Celina Barrera, Hannah N Farfour, Maciej M Mrugala, Mark K Edwin, Jeff A Sloan, and Alyx B Porter

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Supportive care for patients with brain metastases from lung cancer., Akanksha Sharma and Maciej M Mrugala

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Updates on Molecular Targeted Therapies for Intraparenchymal CNS Metastases., Akanksha Sharma, Lauren Singer, and Priya Kumthekar

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Performance and outcomes of transvenous rotational lead extraction: Results from a prospective, monitored, international clinical study., Saumya Sharma, Byron K Lee, Anuj Garg, Robert Peyton, Brian T Schuler, Pamela Mason, Peter Paul Delnoy, Mark M Gallagher, Ramesh Hariharan, Raymond Schaerf, Ruirui Du, Nina D Serratore, and Christoph T Starck

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Current status of gastrointestinal tract cancer brain metastasis and the use of blood-based cancer biomarker biopsy., Yoshiaki Shoji, Satoru Furuhashi, Daniel F Kelly, Anton J Bilchik, Dave S B Hoon, and Matias A Bustos

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Tracheostomy and Improvement in Utilization of Hospital Resources During SARS-CoV-2 Pandemic Surge., Rachel S Sier and Osita Onugha

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Small molecules inhibitors of the heterogeneous ribonuclear protein A18 (hnRNP A18): a regulator of protein translation and an immune checkpoint., Eduardo Solano-Gonzalez, Katherine M Coburn, Wenbo Yu, Gerald M Wilson, Elmar Nurmemmedov, Santosh Kesari, Elizabeth T Chang, Alexander D MacKerell, David J Weber, and France Carrier

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Corrigendum to 'An Introduction to the Cyrcadia Breast Monitor: A Wearable Breast Health Monitoring Device'[Computer Methods and Programs in Biomedicine 197: 105758]., Vinitha Sree S, Rob Royea, Kevin J Buckman, Matt Benardis, Jim Holmes, Ronald L Fletcher, Ng Eyk, U Rajendra Acharya, and Joshua D I Ellenhorn

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Trends in Operative Complex Middle and Upper Maxillofacial Trauma: A 17-Year Study., Peiyi Su, Christian Paquet, Karla O'Dell, David Reinstadler, Niels Kokot, Jay Granzow, Tamara N Chambers, and Amit Kochhar

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Impact of the Olig Family on Neurodevelopmental Disorders., Jenny Szu, Alexandre Wojcinski, Peng Jiang, and Santosh Kesari

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Complication avoidance protocols in endoscopic pituitary adenoma surgery: a retrospective cohort study in 514 patients., Jai Deep Thakur, Alex Corlin, Regin Jay Mallari, Samantha Yawitz, Amalia Eisenberg, Walavan Sivakumar, Chester Griffiths, Ricardo L Carrau, Sarah Rettinger, Pejman Cohan, Howard Krauss, Katherine A Araque, Garni Barkhoudarian, and Daniel F Kelly