Providence research from Southern California locations.

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Submissions from 2022

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Rare adverse events following Covid-19 vaccination: A review, Mohammad Barary, Akanksha Sharma, and See full list of authors in comments

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Blocking UBE2N abrogates oncogenic immune signaling in acute myeloid leukemia., Laura Barreyro, Avery M Sampson, Chiharu Ishikawa, Kathleen M Hueneman, Kwangmin Choi, Mario A Pujato, Somchai Chutipongtanate, Michael Wyder, Wendy D Haffey, Eric O'Brien, Mark Wunderlich, Vighnesh Ramesh, Ellen M Kolb, Cem Meydan, Yaseswini Neelamraju, Lyndsey C Bolanos, Susanne Christie, Molly A Smith, Madeline Niederkorn, Tomoya Muto, Santosh Kesari, Francine E Garrett-Bakelman, Boris Bartholdy, Britta Will, Matthew T Weirauch, James C Mulloy, Zartash Gul, Stephen Medlin, Rhett A Kovall, Ari M Melnick, John P Perentesis, Kenneth D Greis, Elmar Nurmemmedov, William L Seibel, and Daniel T Starczynowski

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Effect of compassion rounds on nurses' professional quality of life on a COVID-19 unit., Deepti Bhatnagar and Martha E F Highfield

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Aortic Stenosis in Elderly Populations: Measuring Value of Patient Shared Decision-Making for Transcatheter Aortic Valve Replacement (TAVR)., Mary Bittner and Giancarlo Lyle-Edrosolo

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Automatic Analysis of Asymmetry in Facial Paralysis Patients Using Landmark-Based Measures., Digbalay Bose, Krishna Somandepalli, Tymon Tai, Courtney Voelker, Shrikanth Narayanan, and Amit Kochhar

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Phase 2 study of AV-GBM-1 (a tumor-initiating cell targeted dendritic cell vaccine) in newly diagnosed Glioblastoma patients: safety and efficacy assessment., Daniela A Bota, Thomas H Taylor, David E Piccioni, Christopher M Duma, Renato V LaRocca, Santosh Kesari, Jose Carrillo, Mehrdad Abedi, Robert D Aiken, Frank P K Hsu, Xiao-Tang Kong, Candace Hsieh, Peter G Bota, Gabriel I Nistor, Hans S Keirstead, and Robert O Dillman

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QLTI-26. INTEGRATION OF NEURO-ONCOLOGY CLINICAL PATHWAYS IN PROVIDENCE SOUTHERN CALIFORNIA CLINICAL RESEARCH NETWORK, Brad Bott, Nanor Bozoyan, Trisha Babcock, Kristen Cushman, Akanksha Sharma, Naveed Wagle, Jose Carrillo, Tiffany Juarez, and Santosh Kesari

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Prognostic Utility of CpG Island Hypermethylated Phenotype in Early-Stage Invasive Primary Melanomas., Matias A Bustos and Dave Hoon

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Cell-free plasma microRNAs that identify patients with glioblastoma., Matias A Bustos, Negin Rahimzadeh, Suyeon Ryu, Rebecca Gross, Linh T Tran, Victor M Renteria-Lopez, Romela Irene Ramos, Amy Eisenberg, Parvinder Hothi, Santosh Kesari, Garni Barkhoudarian, Yuki Takasumi, Charles Cobbs, Daniel F Kelly, and Dave Hoon

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IMPACT OF MORAL INJURY ON WORK PERFORMANCE IN NURSES FOLLOWING THE COVID-19 SURGES, Annette Callis, Trisha Saul, and Ross Bindler

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DNA methylome combined with chromosome cluster-oriented analysis provides an early signature for cutaneous melanoma aggressiveness., Arnaud Carrier, Cécile Desjobert, Loic Ponger, Laurence Lamant, Matias A Bustos, Jorge Torres-Ferreira, Rui Henrique, Carmen Jeronimo, Luisa Lanfrancone, Audrey Delmas, Gilles Favre, Antoine Daunay, Florence Busato, Dave S B Hoon, Jorg Tost, Chantal Etievant, Joëlle Riond, and Paola B Arimondo

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QLTI-22. IMPROVING BRAIN CANCER PATIENT ACCESS TO CLINICAL TRIALS ACROSS SEVEN COMMUNITY HOSPITALS, THE PROVIDENCE SOUTHERN CALIFORNIA CLINICAL RESEARCH NETWORK, Jose Carrillo, Naveed Wagle, Akanksha Sharma, Tiffany Juarez, Minhdan Nguyen, Judy D Truong, Timothy E. Byun, Brad Bott, Nanor Bozoyan, David J Park, and Santosh Kesari

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Smart Consumer Wearables as Digital Diagnostic Tools: A Review., Shweta Chakrabarti, Nupur Biswas, Lawrence D Jones, Santosh Kesari, and Shashaanka Ashili

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Economic considerations for the inclusion of midurethral sling as a treatment strategy for stress urinary incontinence., Olivia H Chang, Lauren A Cadish, Beri M Ridgeway, and Jonathan P Shepherd

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Topical therapy for regression and melanoma prevention of congenital giant nevi., Yeon Sook Choi, Tal H Erlich, Max von Franque, Inbal Rachmin, Jessica L Flesher, Erik B Schiferle, Yi Zhang, Marcello Pereira da Silva, Alva Jiang, Allison S Dobry, Mack Su, Sharon Germana, Sebastian Lacher, Orly Freund, Ezra Feder, Jose L Cortez, Suyeon Ryu, Tamar Babila Propp, Yedidyah Leo Samuels, Labib R Zakka, Marjan Azin, Christin E Burd, Norman E Sharpless, X Shirley Liu, Clifford Meyer, William Gerald Austen, Branko Bojovic, Curtis L Cetrulo, Martin C Mihm, Dave S Hoon, Shadmehr Demehri, Elena B Hawryluk, and David E Fisher

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NCMP-07. CASE SERIES OF REGULARLY SCHEDULED MANNITOL INFUSIONS SHOWING WITH PROLONGED CLINICAL BENEFIT FOR MANAGEMENT OF CEREBRAL EDEMA IN GLIOMAS, Jared Chow, Jose Carrillo, Santosh Kesari, Akanksha Sharma, Minhdan Nguyen, Judy D Truong, and Naveed Wagle

Neoadjuvant chemotherapy improves outcomes in resectable pancreatic adenocarcinoma, Wade Christopher, Sean Nassoiy, Rebecca Marcus, Jennifer Keller, Shu-Ching Chang, Trevan Fischer, Anton Bilchik, and Melanie Goldfarb

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Sentinel lymph node melanoma metastases: Assessment of tumor burden for clinical prediction of outcome in the first Multicenter Selective Lymphadenectomy Trial (MSLT-I)., Alistair J Cochran, Duan-Ren Wen, Rong-Rong Huang, Payam Abrishami, Chandra Smart, Scott Binder, Richard A Scolyer, John F Thompson, Stacey Stern, Lisa Van Kreuningen, David E Elashoff, Myung-Shin Sim, He-Jing Wang, Mark Faries, and MSLT-I Study Group

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Genomic Correlates of Outcome in Tumor-Infiltrating Lymphocyte Therapy for Metastatic Melanoma., Caitlin A Creasy, Yuzhong Jeff Meng, Marie-Andrée Forget, Tatiana Karpinets, Katarzyna Tomczak, Chip Stewart, Carlos A Torres-Cabala, Shari Pilon-Thomas, Amod A Sarnaik, James J Mule, Levi Garraway, Matias A Bustos, Jianhua Zhang, Sapna P Patel, Adi Diab, Isabella C Glitza, Cassian Yee, Hussein Tawbi, Michael K Wong, Jennifer McQuade, Dave S B Hoon, Michael A Davies, Patrick Hwu, Rodabe N Amaria, Cara Haymaker, Rameen Beroukhim, and Chantale Bernatchez

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Easing the Journey-an Updated Review of Palliative Care for the Patient with High-Grade Glioma., Rita C Crooms, Margaret O Johnson, Heather Leeper, Ambereen Mehta, Michelle McWhirter, and Akanksha Sharma

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Role Delineation of the Code Blue Team: A Quasi-Experimental Study During COVID-19., Danika DeGroot and Annette Callis

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Latinx attitudes, barriers, and experiences with genetic counseling and testing: A systematic review., Heather A Dron, Daiana Bucio, Jennifer L Young, Holly K Tabor, and Mildred K Cho

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Contemporary national trends and disparities for head CT use in emergency department settings: Insights from National Hospital Ambulatory Medical Care Survey (NHAMCS) 2007-2017., Prachi Dubey, Anshul Saxena, John E Jordan, Zhaoying Xian, Zulqarnain Javed, Gaurav Jindal, Farhaan Vahidy, Dirk H Sostman, and Khurram Nasir

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Epigenetic Signatures Predict Pathologic Nodal Stage in Breast Cancer Patients with Estrogen Receptor-Positive, Clinically Node-Positive Disease., Miquel Ensenyat-Mendez, Dennis Rünger, Javier I Orozco, Julie Le, Jennifer L Baker, Joanne Weidhaas, Diego M Marzese, and Maggie L DiNome

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How I treat brain metastases of melanoma., Z Eroglu, T O Topcu, H M Yu, and K A Margolin

Challenging Implicit Bias Using the Flipped Classroom, Brandy Rachel Frye and Marta De Volt

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Correction: Interplay between soluble CD74 and macrophage-migration inhibitory factor drives tumor growth and influences patient survival in melanoma., Yasunari Fukuda, Matias A Bustos, Sung-Nam Cho, Jason Roszik, Suyeon Ryu, Victor M Lopez, Jared K Burks, Jeffrey E Lee, Elizabeth A Grimm, Dave S B Hoon, and Suhendan Ekmekcioglu

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Interplay between soluble CD74 and macrophage-migration inhibitory factor drives tumor growth and influences patient survival in melanoma., Yasunari Fukuda, Matias A Bustos, Sung-Nam Cho, Jason Roszik, Suyeon Ryu, Victor M Renteria-Lopez, Jared K Burks, Jeffrey E Lee, Elizabeth A Grimm, Dave Hoon, and Suhendan Ekmekcioglu

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Differentiation of Subjective Cognitive Decline, Mild Cognitive Impairment, and Dementia Using qEEG/ERP-Based Cognitive Testing and Volumetric MRI in an Outpatient Specialty Memory Clinic., Aarthi S Ganapathi, Ryan M Glatt, Tess H Bookheimer, Emily S Popa, Morgan L Ingemanson, Casey J Richards, John F Hodes, Kyron P Pierce, Colby B Slyapich, Fatima Iqbal, Jenna Mattinson, Melanie G Lampa, Jaya M Gill, Ynez M Tongson, Claudia L Wong, Mihae Kim, Verna R Porter, Santosh Kesari, Somayeh Meysami, Karen J Miller, Jennifer E Bramen, David A Merrill, and Prabha Siddarth

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A case of recurrent aneurysm resulting from dual antiplatelet plus anticoagulation after confirmed aneurysm closure following coil-assisted flow diversion., Thomas R Geisbush, Benjamin Pulli, Dylan N Wolman, Arjun V Pendharkar, and Nicholas A Telischak

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Verification of a Novel Minimally Invasive Device for the Isolation of Rare Circulating Tumor Cells (CTC) in Cancer Patients' Blood., Paul Friedrich Geus, Felix Hehnen, Sophia Krakowski, Klaus Lücke, Dave Hoon, Nikolaj Frost, Ulrich Kertzscher, and Gabi Wendt

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Differences in the management of thyroid nodules in children and adolescents as compared to adults., Melanie Goldfarb and Catherine Dinauer

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Survivorship, Quality of Life, and Transition to Adult Care for Pediatric and Adolescent Thyroid Cancer Survivors., Melanie Goldfarb and Aime T Franco

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Safety of Tumor Treating Fields (TTFields) therapy in pediatric patients with malignant brain tumors: Post-marketing surveillance data., Stewart Goldman, Ashley Margol, Eugene I Hwang, Kazuhiro Tanaka, Bogdana Suchorska, John R Crawford, and Santosh Kesari

Nurses' experiences using online resources for patient and family education, Carrie Grinstead, Sarah Sumner, and Martha Inofuentes

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Clinical Course of Two Patients with COVID-19 Respiratory Failure After Administration of the Anticancer Small Molecule, RRx-001., Terese Catherine Hammond, Raymond C Lee, Bryan Oronsky, Tony R Reid, Scott Caroen, Tiffany M Juarez, Jaya Gill, Annie Heng, and Santosh Kesari

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Long-Term Outcomes of Patients on a Phase II Prospective Trial of Oligometastatic Hormone-Sensitive Prostate Cancer Treated with Androgen Deprivation and External Beam Radiation., Claire Hao, Colton Ladbury, Yung Lyou, Saro Manoukian, Christopher Ruel, Paul Frankel, Tanya Dorff, Jeffrey Wong, Sumanta Pal, Przemyslaw Twardowski, and Savita Dandapani

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Health Equity: What the Neuroradiologist Needs to Know., J E Jordan and G B McGinty

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Predicting Regional Lymph Node Recurrence in the Modern Age of Tumor-Positive Sentinel Node Melanoma: The Role of the First Postoperative Ultrasound., Jennifer Keller, Stacey Stern, Shu-Ching Chang, Rebecca Marcus, Jessica Weiss, Sean Nassoiy, Wade Christopher, Trevan Fischer, and Richard Essner

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Psychedelic-Assisted Therapy and Psychedelic Science: A Review and Perspective on Opportunities in Neurosurgery and Neuro-Oncology., Daniel F Kelly, Keith Heinzerling, Akanksha Sharma, Shanthi Gowrinathan, Karina Sergi, and Regin Jay Mallari

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BETA PRIME: Phase I study of AdAPT-001 as monotherapy and combined with a checkpoint inhibitor in superficially accessible, treatment-refractory solid tumors., Santosh Kesari, Alberto Bessudo, Brian R Gastman, Anthony P Conley, Victoria M Villaflor, Lisle M Nabell, DeLisa Madere, Emma Chacon, Christina Spencer, Li Li, Christopher Larson, Tony Reid, Scott Caroen, Bryan Oronsky, Meaghan Stirn, Jeannie Williams, and Minal A Barve

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Clinical and Economic Profile of Homeless Young Adults with Stroke in the United States, 2002-2017., Safi U Khan, Siva H Yedlapati, Muhammad Zia Khan, Salim S Virani, Michael J Blaha, Garima Sharma, John E Jordan, Bita A Kash, Farhaan S Vahidy, Adeel Arshad, Elias Mossialos, and Khurram Nasir

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A novel operator-independent noninvasive device for assessing arterial reactivity., Kellen A Knowles, Kerry J Stewart, Joseph Tejan, Pamela Ouyang, Elizabeth V Ratchford, Laura Sullam, Kathy Magliato, Michael D Whitt, and Harry A Silber

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Genomic Amplification of, Yuta Kobayashi, Matias A Bustos, Yoshiaki Shoji, Ron D Jachimowicz, Yosef Shiloh, and Dave S B Hoon

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Urine Cell-Free MicroRNAs in Localized Prostate Cancer Patients., Yoko Koh, Matias A Bustos, Jamie Moon, Rebecca Gross, Romela Irene Ramos, Suyeon Ryu, Jane Choe, Selena Y Lin, Warren M Allen, David L Krasne, Timothy G Wilson, and Dave Hoon

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More autopsy studies are needed to understand the pathogenesis of severe COVID-19., Scott P Layne, Kathie-Anne Walters, John C Kash, and Jeffery K Taubenberger

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Treatment of Cushing's Disease with Pituitary-Targeting Seliciclib., Ning Ai Liu, Anat Ben-Shlomo, John D Carmichael, Christina Wang, Ronald S Swerdloff, Anthony P Heaney, Garni Barkhoudarian, Daniel Kelly, Mazen Noureddin, Lin Lu, Manish Desai, Yana Stolyarov, Kevin Yuen, Adam N Mamelak, James Mirocha, Mourad Tighiouart, and Shlomo Melmed

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Correction: miR-29c plays a suppressive role in breast cancer by targeting the TIMP3/STAT1/FOXO1 pathway., Wan Li, Jie Yi, Xiangjin Zheng, Shiwei Liu, Weiqi Fu, Liwen Ren, Li Li, Dave Hoon, Jinhua Wang, and Guanhua Du

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Cross-Sectional Analysis of Burnout, Secondary Traumatic Stress, and Compassion Satisfaction Among Emergency Nurses in Southern California Working Through the COVID-19 Pandemic., Jamie Lopez, Ross J Bindler, and Jillian Lee

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Systemic Therapy Is Associated with Improved Oncologic Outcomes in Resectable Stage II/III Intrahepatic Cholangiocarcinoma: An Examination of the National Cancer Database over the Past Decade., Rebecca Marcus, Wade Christopher, Jennifer Keller, Sean Nassoiy, Shu-Ching Chang, Melanie Goldfarb, Ronald Wolf, and Zeljka Jutric

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Learning from Each Other: Peer-Reviewed Literature Searching, Heather Martin, Danielle Linden, and Carrie Grinstead

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Hypoxia induces HIF1α-dependent epigenetic vulnerability in triple negative breast cancer to confer immune effector dysfunction and resistance to anti-PD-1 immunotherapy., Shijun Ma, Yue Zhao, Wee Chyan Lee, Li-Teng Ong, Puay Leng Lee, Zemin Jiang, Gokce Oguz, Zhitong Niu, Min Liu, Jian Yuan Goh, Wenyu Wang, Matias A Bustos, Sidse Ehmsen, Adaikalavan Ramasamy, Dave Hoon, Henrik J Ditzel, Ern Yu Tan, Qingfeng Chen, and Qiang Yu

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Reply by Authors., Surena F Matin, Phillip M Pierorazio, Nir Kleinmann, John L Gore, Ahmad Shabsigh, Brian Hu, Karim Chamie, Guilherme Godoy, Scott G Hubosky, Marcelino Rivera, Michael O'Donnell, Marcus Quek, Jay D Raman, John J Knoedler, Douglas Scherr, Christopher Weight, Alon Weizer, Michael Woods, Hristos Kaimakliotis, Angela B Smith, Jennifer M Linehan, Jonathan Coleman, Mitchell R Humphreys, Raymond Pak, David Lifshitz, Michael Verni, Ifat Klein, Marina Konorty, Dalit Strauss-Ayali, Gil Hakim, Elyse Seltzer, Mark Schoenberg, and Seth P Lerner

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ATF6-mediated signaling contributes to PARP Inhibitor Resistance in Ovarian Cancer., Alexandra McMellen, Tomomi M Yamamoto, Lubna Qamar, Brooke E Sanders, Lily L Nguyen, Daniela Ortiz Chavez, Jaidev Bapat, Amber Berning, Miriam D Post, Joshua Johnson, Kian Behbakht, Elmar Nurmemmedov, Edward B Chuong, and Benjamin G Bitler

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COVID-19 driven decline in emergency visits: Has it continued, is it permanent, and what does it mean for emergency physicians?, Glenn Melnick, June F O'Leary, Ben A Zaniello, and Luis Abrishamian

Ongoing use of SSRIs and the hospital course of COVID-19 patients: a retrospective outcome analysis, Sherri Mendelson and Steven Rauchman

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Handgrip Strength Is Related to Hippocampal and Lobar Brain Volumes in a Cohort of Cognitively Impaired Older Adults with Confirmed Amyloid Burden., Somayeh Meysami, Cyrus A Raji, Ryan M. Glatt, Emily S Popa, Aarthi Ganapathi, Tess Bookheimer, Colby B Slyapich, Kyron P Pierce, Casey J Richards, Melanie G Lampa, Jaya Mini Gill, Molly Rapozo, John F Hodes, Ynez M Tongson, Claudia L Wong, Mihae Kim, Verna R Porter, Scott Kaiser, Stella Panos, Richelin V Dye, Karen J Miller, Susan Y Bookheimer, Neil A Martin, Santosh Kesari, Daniel F Kelly, Jennifer Bramen, Prabha Siddarth, and David A Merrill

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Cost-effectiveness of prophylactic retropubic sling at the time of vaginal prolapse surgery., Tsung Mou, Lauren A Cadish, Elizabeth L Gray, and C Emi Bretschneider

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Therapeutic Value of Sentinel Lymph Node Biopsy in Patients With Melanoma: A Randomized Clinical Trial., Multicenter Selective Lymphadenectomy Trials Study Group, Jessica S Crystal, John F Thompson, John Hyngstrom, Corrado Caracò, Jonathan S Zager, Tiina Jahkola, Tawnya L Bowles, Elisabetta Pennacchioli, Peter D Beitsch, Harald J Hoekstra, Marc Moncrieff, Christian Ingvar, Alexander van Akkooi, Michael S Sabel, Edward A Levine, Doreen Agnese, Michael Henderson, Reinhard Dummer, Rogerio I Neves, Carlo Riccardo Rossi, John M Kane, Steven Trocha, Frances Wright, David R Byrd, Maurice Matter, Eddy C Hsueh, Alastair MacKenzie-Ross, Mark Kelley, Patrick Terheyden, Tara L Huston, Jeffrey D Wayne, Heather Neuman, B Mark Smithers, Charlotte E Ariyan, Darius Desai, Jeffrey E Gershenwald, Shlomo Schneebaum, Anja Gesierich, Lisa K Jacobs, James M Lewis, Kelly M McMasters, Cristina O'Donoghue, Andre van der Westhuizen, Armando Sardi, Richard Barth, Robert Barone, J Greg McKinnon, Craig L Slingluff, Jeffrey M Farma, Erwin Schultz, Randall P Scheri, Sergi Vidal-Sicart, Manuel Molina, Alessandro A E Testori, Lee Foshag, Lisa Van Kreuningen, He-Jing Wang, Myung-Shin Sim, Richard A Scolyer, David E Elashoff, Alistair J Cochran, and Mark B Faries

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Treatment Utilization and Outcomes for Locally Advanced Rectal Cancer in Older Patients., Sean Nassoiy, Wade Christopher, Rebecca Marcus, Jennifer Keller, Jessica Weiss, Shu-Ching Chang, Leland Foshag, Richard Essner, Trevan Fischer, and Melanie Goldfarb

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Evolving management of early stage pancreatic adenocarcinoma in older patients., Sean Nassoiy, Wade O Christopher, Rebecca Marcus, Jennifer Keller, Jessica Weiss, Shu-Ching Chang, Richard Essner, Lee Foshag, Trevan Fischer, and Melanie Goldfarb

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Cesarean delivery on maternal request in the United States from 1999 to 2015: a comment., David L Newfield

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Leading with self-empathy: Self-empathy can help leaders find meaning and purpose during difficult times, Stephanie Nolan

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IFI16-dependent STING signaling is a crucial regulator of anti-HER2 immune response in HER2+ breast cancer., Li-Teng Ong, Wee Chyan Lee, Shijun Ma, Gokce Oguz, Zhitong Niu, Yi Bao, Mubaraka Yusuf, Puay Leng Lee, Jian Yuan Goh, Panpan Wang, Kylie Su Mei Yong, Qingfeng Chen, Wenyu Wang, Adaikalavan Ramasamy, Dave Hoon, Henrik J Ditzel, Ern Yu Tan, Soo Chin Lee, and Qiang Yu

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A Case of Brachial Lymph Node Recurrences after the Resection of Locally Advanced Breast Cancer., Kayono Onishi, Rurina Watanuki, Takamichi Yokoe, Tsuguo Iwatani, Chisako Yamauchi, and Tatsuya Onishi

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ASO Author Reflections: Breast-Conserving Therapy: A Safe Option in Young Patients with Early-Stage Breast Cancer., Javier I Orozco, Crystal E Fancher, and Janie Grumley

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ASO Visual Abstract: Machine Learning-Based Epigenetic Classifiers for Axillary Staging of Patients with ER-Positive Early-Stage Breast Cancer., Javier I J Orozco, Julie Le, Miquel Ensenyat-Mendez, Jennifer L Baker, Joanne Weidhaas, Alexandra Klomhaus, Diego M Marzese, and Maggie L DiNome

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ASO Visual Abstract: Impact of Locoregional Treatment on Survival in Young Patients with Early-Stage Breast Cancer Undergoing Upfront Surgery., Javier I Orozco, Jennifer Keller, Shu-Ching Chang, Crystal E Fancher, and Janie Grumley

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Impact of Locoregional Treatment on Survival in Young Patients with Early-Stage Breast Cancer undergoing Upfront Surgery., Javier I Orozco, Jennifer Keller, Shu-Ching Chang, Crystal E Fancher, and Janie Grumley

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ASO Author Reflections: Molecular Signatures May Render Surgical Staging of the Axilla Obsolete., Javier I Orozco, Julie Le, Jennifer L Baker, Diego M Marzese, and Maggie L DiNome

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Machine Learning-Based Epigenetic Classifiers for Axillary Staging of Patients with ER-Positive Early-Stage Breast Cancer., Javier I Orozco, Julie Le, Miquel Ensenyat-Mendez, Jennifer L Baker, Joanne Weidhaas, Alexandra Klomhaus, Diego M Marzese, and Maggie L DiNome

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Inhaled Sargramostim (Recombinant Human Granulocyte-Macrophage Colony-Stimulating Factor) for COVID-19-Associated Acute Hypoxemia: Results of the Phase 2, Randomized, Open-Label Trial (iLeukPulm)., Robert Paine, Robert Chasse, E Scott Halstead, Jay Nfonoyim, David J Park, Timothy E. Byun, Bela Patel, Guido Molina-Pallete, Estelle S Harris, Fiona Garner, Lorinda Simms, Sanjeev Ahuja, John L McManus, and Debasish F Roychowdhury

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Molecular alterations associated with improved outcome in patients with glioblastoma treated with Tumor-Treating Fields., Manjari Pandey, Joanne Xiu, Sandeep Mittal, Jia Zeng, Michelle Saul, Santosh Kesari, Amir Azadi, Herbert Newton, Karina Deniz, Katherine Ladner, Ashley Sumrall, W Michael Korn, and Emil Lou

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#754 A PHASE 1/2 STUDY OF ASP1570 IN PARTICIPANTS WITH LOCALLY ADVANCED OR METASTATIC SOLID TUMORS WHO HAVE PROGRESSED ON, OR ARE INELIGIBLE FOR, ALL AVAILABLE STANDARD THERAPIES, Manish Patel, David J Park, and See full list of authors in comments

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MTAP loss: a possible therapeutic approach for glioblastoma., C Pawan K Patro, Nupur Biswas, Sandeep C Pingle, Feng Lin, Misa Anekoji, Lawrence D Jones, Santosh Kesari, Feng Wang, and Shashaanka Ashili

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Genetic polymorphisms and correlation with treatment induced cardiotoxicity and prognosis in breast cancer patients., Parvin Peddi, Peter A Fasching, Duan Liu, Emmanuel Quinaux, Nicholas J Robert, Vicente Valero, John Crown, Carla Falkson, Adam Brufsky, Julie M Cunningham, Richard M Weinshilboum, Tadeusz Pienkowski, Wolfgang Eiermann, Miguel Martín, Valerie Bee, Xiaoyan Wang, Liewei Wang, Eric Yang, Dennis J Slamon, and Sara A Hurvitz

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Normothermic Regional Perfusion Requires Careful Ethical Analysis Before Adoption Into Donation After Circulatory Determination of Death., Harry Peled, Sajen Mathews, David Rhodes, and James L Bernat

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Does Residual Invasive Disease in Wide Local Excision after Diagnosis with Partial Biopsy Technique Influence Survival in Melanoma? Matched-Pair Analysis of Multicenter Selective Lymphadenectomy Trial I and II., Judi Anne B Ramiscal, Stacey L Stern, Ana K Wilson, Patrick D Lorimer, Nathaniel A Lee, Melanie R Goldfarb, Leland J Foshag, and Trevan D Fischer

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Dense data enables 21th century clinical trials., Jared C Roach, John F Hodes, Cory C Funk, William R Shankle, David A Merrill, Leroy Hood, and Jennifer Bramen

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A Phase III, Multicenter, Randomized Controlled Trial Investigating 1-cm Versus 2-cm Surgical Excision Margins for Stage II Primary Cutaneous Melanoma (MelMarT-II)., Alexander J Rossi, Emily A Verbus, Mark Faries, Marc Moncrieff, Michael Henderson, Jonathan M Hernandez, and Michael C Lowe

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Disparities in the impact of the AJCC 8th edition staging system on differentiated thyroid cancer outcomes., Juan A Santamaria-Barria, Amanda N Graff-Baker, Shu-Ching Chang, Adam Khader, Anthony J Scholer, Mary Garland-Kledzik, and Melanie Goldfarb

Nurses Not on the Front Line of the Covid-19 Pandemic, Trisha Saul, Shelly Hicks, Geri Harmon, and Sherri Mendelson

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Validating biologic age in selecting elderly patients with pancreatic cancer for surgical resection., Anthony J Scholer, Rebecca Marcus, Mary Garland-Kledzik, Shu-Ching Chang, Adam Khader, Juan Santamaria-Barria, Zeljka Jutric, Ronald Wolf, and Melanie Goldfarb

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Glioblastoma Embryonic-like Stem Cells Exhibit Immune-Evasive Phenotype., Borja Sesé, Sandra Íñiguez-Muñoz, Miquel Ensenyat-Mendez, Pere Llinàs-Arias, Guillem Ramis, Javier I Orozco, Silvia Fernández de Mattos, Priam Villalonga, and Diego M Marzese

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The impact of mentoring on early career faculty: Assessment of a virtual mentoring program., Akanksha Sharma, Heather Leeper, Soo Bang, Donna Molaie, and Alyx B. Porter

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Advances in the Diagnosis and Treatment of Leptomeningeal Disease., Akanksha Sharma, Justin T Low, and Priya Kumthekar

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Efficacy and safety of trifluridine/tipiracil in older and younger patients with metastatic gastric or gastroesophageal junction cancer: subgroup analysis of a randomized phase 3 study (TAGS)., Kohei Shitara, Toshihiko Doi, Hisashi Hosaka, Peter Thuss-Patience, Armando Santoro, Federico Longo, Ozgur Ozyilkan, Irfan Cicin, David J Park, Aziz Zaanan, Carles Pericay, Mustafa Özgüroğlu, Maria Alsina, Lukas Makris, Karim A Benhadji, and David H Ilson

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A phase 1b single-arm trial of intratumoral oncolytic virus V937 in combination with pembrolizumab in patients with advanced melanoma: results from the CAPRA study., Ann W Silk, Steven O'Day, Howard L Kaufman, Jennifer Bryan, Jacqueline T Norrell, Casey Imbergamo, Daniella Portal, Edwin Zambrano-Acosta, Marisa Palmeri, Seymour Fein, Cai Wu, Leslie Guerreiro, Daniel Medina, Praveen K Bommareddy, Andrew Zloza, Bernard A Fox, Carmen Ballesteros-Merino, Yixin Ren, Darren Shafren, Mark Grose, Joshua A Vieth, and Janice M Mehnert

Barriers Identified By Nursing Leaders in Supporting Nursing Research, Marietta Sperry, Sherri Mendelson, and Eric Southard

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Malignant Pilomatricoma of the Lower Extremity: A Difficult and Rare Diagnosis., Chaitra Subramanyam, Paige Dyrek, Xu Yao, and Martin H Kay

Mental Health First Aid: Training during the pandemic, Sarah Sumner and Sharon Elliott

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Anomaly Detection Framework for Wearables Data: A Perspective Review on Data Concepts, Data Analysis Algorithms and Prospects., Jithin S Sunny, C Pawan K Patro, Khushi Karnani, Sandeep C Pingle, Feng Lin, Misa Anekoji, Lawrence D Jones, Santosh Kesari, and Shashaanka Ashili

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Multiple Early Factors Anticipate Post-Acute COVID-19 Sequelae, Yapeng Su, Dan Yuan, Daniel G. Chen, Rachel H. Ng, Kai Wang, Jongchan Choi, Sarah Li, Sunga Hong, Rongyu Zhang, Jingyi Xie, Sergey A Kornilov, Kelsey Scherler, Ana Jimena Pavlovitch-Bedzyk, Shen Dong, Christopher Lausted, Inyoul Lee, Shannon Fallen, Chengzhen L Dai, Priyanka Baloni, Brett Smith, Venkata R Duvvuri, Kristin G. Anderson, Jing Li, Fan Yang, Caroline J. Duncombe, Denise J. McCulloch, Clifford Rostomily, Pamela Troisch, Jing Zhou, Sean Mackay, Quinn DeGottardi, Damon H. May, Ruth Taniguchi, Rachel M. Gittelman, Mark Klinger, Thomas M. Snyder, Ryan Roper, Gladys Wojciechowska, Kim Murray, Rick Edmark, Simon Evans, Lesley Jones, Yong Zhou, Lee Rowen, Rachel Liu, William Chour, Heather A Algren, William R Berrington, Julie A Wallick, Rebecca A. Cochran, Mary Micikas, ISB-Swedish COVID19 Biobanking Unit, Terri Wrin, Christos J. Petropoulos, Hunter R. Cole, Trevan D Fischer, Wei Wei, Dave SB Hoon, Nathan D Price, Naeha Subramanian, Joshua A. Hill, Jennifer J Hadlock, Andrew T. Magis, Antoni Ribas, Lewis L. Lanier, Scott D. Boyd, Jeffrey A. Bluestone, Helen Chu, Leroy Hood, Raphael Gottardo, Philip D. Greenberg, Mark M. Davis, Jason D Goldman, and James R. Heath

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Critical appraisal of minimally invasive keyhole surgery for intracranial meningioma in a large case series., Jai Deep Thakur, Regin Jay Mallari, Alex Corlin, Samantha Yawitz, Amy Eisenberg, John Rhee, Walavan Sivakumar, Howard Krauss, Neil A Martin, Chester Griffiths, Garni Barkhoudarian, and Daniel F Kelly

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The TARGIT-A Randomized Trial: TARGIT-IORT Versus Whole Breast Radiation Therapy: Long-Term Local Control and Survival., Jayant S Vaidya, Max Bulsara, Frederik Wenz, Elena Sperk, Samuele Massarut, Michael Alvarado, Norman R Williams, Chris Brew-Graves, Marcelle Bernstein, Dennis Holmes, Lorenzo Vinante, Steffi Pigorsch, Steinar Lundgren, Valery Uhl, David Joseph, Jeffrey S Tobias, and TARGIT-A authors

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CTNI-51. FEASIBILITY AND SAFETY OF NEUROSURGICAL RESECTION AND INTRA-OPERATIVE RADIATION THERAPY USING THE XOFT AXXENT ELECTRONIC BRACHYTHERAPY SYSTEM AND BEVACIZUMAB IN RECURRENT GLIOBLASTOMA, Naveed Wagle, Garni Barkhoudarian, Lisa Chaiken, Robert Wollman, Akanksha Sharma, Jose Carrillo, Minhdan Nguyen, Judy D Truong, Jared Chow, Emma Chacon, and Santosh Kesari

Geno4ME: establishment of an equitable whole-genome sequencing-based platform for clinical screening in a large healthcare system, Josiah Wagner, I A. Lucas-Beckett, K R. Emery, B A. Cosgrove, John T. Welle, K Jade, N D. Wagner, J Rinaldi, Lindsay Dickey, K G. Jones, L Yuan, E M. Shull, J Clemens, Keri Vartanian, A T. Magis, M B. Campbell, Brian Piening, Carlo Bifulco, and Ora K. Gordon

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Novel Therapeutics and Treatment Strategies for Medullary Thyroid Cancer., Evan Walgama, Naifa Busaidy, and Mark Zafereo

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Germline biomarkers predict toxicity to anti-PD1/PDL1 checkpoint therapy., Joanne Weidhaas, Nicholas Marco, Aaron W Scheffler, Anusha Kalbasi, Kirk Wilenius, Emily Rietdorf, Jaya Mini Gill, Mara Heilig, Caroline Desler, Robert K Chin, Tania Kaprealian, Susan McCloskey, Ann Raldow, Naga P Raja, Santosh Kesari, Jose Carrillo, Alexandra Drakaki, Mark Scholz, and Donatello Telesca

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Design and Validation of a Whole-Genome Sequencing- Based Assay for Population Health, John Welle, Brian D. Piening, Josiah T Wagner, Isabelle Lucas-Beckett, T Ward, Benjamin Cosgrove, Eric Shull, R Rattray, Marina Pukay, M Ricks, Kimberly K Childers, Jennifer M Linehan, Mary Campbell, Ora K Gordon, and Carlo Bifulco