Providence research from Washington locations.

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Submissions from 2022

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Cerebral Regional Tissue Oxygenation as Surrogate for Blood Loss in Nonhuman Primate Models of Shock., Clifford G Morgan, Leslie E Neidert, Emily N Hathaway, Michael M Tiller, Sylvain Cardin, and Jacob J Glaser

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Sodium-Glucose Cotransporter 2 Inhibitors and New-onset Type 2 Diabetes in Adults With Prediabetes: Systematic Review and Meta-analysis of Randomized Controlled Trials., Yuichiro Mori, O Kenrik Duru, Katherine R Tuttle, Shingo Fukuma, Daisuke Taura, Norio Harada, Nobuya Inagaki, and Kosuke Inoue

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Sodium-Glucose Cotransporter 2 Inhibitors and New-onset Type 2 Diabetes in Adults with Prediabetes: systematic review and meta-analysis of randomized controlled trials., Yuichiro Mori, O Kenrik Duru, Katherine R Tuttle, Shingo Fukuma, Daisuke Taura, Norio Harada, Nobuya Inagaki, and Kosuke Inoue

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Synthetic lethal kinases in Ras/p53 mutant squamous cell carcinoma., Russell Moser, Kay E Gurley, Olga Nikolova, Guangrong Qin, Rashmi Joshi, Eduardo Mendez, Ilya Shmulevich, Amanda Ashley, Carla Grandori, and Christopher J Kemp

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KDOQI US Commentary on the KDIGO 2020 Clinical Practice Guideline for Diabetes Management in CKD., Amy K Mottl, Radica Alicic, Christos Argyropoulos, Frank C Brosius, Michael Mauer, Mark Molitch, Robert G Nelson, Leigh Perreault, and Susanne B Nicholas

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Standardized annotation of translated open reading frames., Jonathan M Mudge, Jorge Ruiz-Orera, John R Prensner, Marie A Brunet, Ferriol Calvet, Irwin Jungreis, Jose Manuel Gonzalez, Michele Magrane, Thomas F Martinez, Jana Felicitas Schulz, Yucheng T Yang, M Mar Albà, Julie L Aspden, Pavel V Baranov, Ariel A Bazzini, Elspeth Bruford, Maria Jesus Martin, Lorenzo Calviello, Anne-Ruxandra Carvunis, Jin Chen, Juan Pablo Couso, Eric W Deutsch, Paul Flicek, Adam Frankish, Mark Gerstein, Norbert Hubner, Nicholas T Ingolia, Manolis Kellis, Gerben Menschaert, Robert L Moritz, Uwe Ohler, Xavier Roucou, Alan Saghatelian, Jonathan S Weissman, and Sebastiaan van Heesch

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Trends in treatment patterns and costs of care among patients with advanced stage cervical cancer., Fernanda Musa, Elizabeth Brouwer, Jie Ting, Naomi R M Schwartz, Andy Surinach, Lisa Bloudek, and Scott D Ramsey

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Management of Post-Infectious Anosmia and Hyposmia: A Systematic Review., Amit K Nag, Abdul K Saltagi, Mohamad Z Saltagi, Arthur W Wu, Thomas S Higgins, Anna Knisely, Jonathan Y Ting, and Elisa A Illing

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Instrument selection for the ASAS core outcome set for axial spondyloarthritis., Victoria Navarro-Compán, Anne Boel, Annelies Boonen, Philip Mease, Maxime Dougados, Uta Kiltz, Robert B M Landewé, Xenofon Baraliakos, Wilson Bautista-Molano, Praveena Chiowchanwisawakit, Hanne Dagfinrud, Lara Fallon, Marco Garrido-Cumbrera, Lianne Gensler, Bassel Kamal ElZorkany, Nigil Haroon, Yu Heng Kwan, Pedro M Machado, Walter Maksymowych, Anna Molto, Natasha de Peyrecave, Denis Poddubnyy, Mikhail Protopopov, Sofia Ramiro, In-Ho Song, Salima van Weely, and Désirée van der Heijde

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GLP-1 Receptor Agonists in the Treatment of Patients with Type 2 Diabetes and Chronic Kidney Disease, Joshua J Neumiller, Radica Alicic, and Katherine R. Tuttle

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Clinical Evidence and Proposed Mechanisms for Cardiovascular and Kidney Benefits from Sodium-Glucose Co-transporter-2 Inhibitors., Joshua J Neumiller, Fredrick J Lienhard, Radica Alicic, and Katherine Tuttle

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Clinical Evidence and Proposed Mechanisms for Cardiovascular and Kidney Benefits from Sodium-Glucose Co-transporter-2 Inhibitors., Joshua J Neumiller, Fredrick J Lienhard, Radica Z Alicic, and Katherine R Tuttle

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Optimizing use of SGLT2 inhibitors and other evidence-based therapies to improve outcomes in patients with type 2 diabetes and chronic kidney disease: An opportunity for pharmacists., Joshua J Neumiller, Jay H Shubrook, Tom Manley, Radica Alicic, and Katherine Tuttle

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Constraint-Based Reconstruction and Analyses of Metabolic Models: Open-Source Python Tools and Applications to Cancer., Rachel H Ng, Jihoon W Lee, Priyanka Baloni, Christian Diener, James R Heath, and Yapeng Su

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Black Lives Matter: Moving from passion to action in academic medical institutions., Bich-May Nguyen, Jessica Guh, and Brandi Freeman

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GPR17 Signaling Activation by CHBC Agonist Induced Cell Death via Modulation of MAPK Pathway in Glioblastoma., Phung Nguyen, Phuong Doan, Akshaya Murugesan, Thiyagarajan Ramesh, Tatu Rimpilainen, Nuno R Candeias, Olli Yli-Harja, and Meenakshisundaram Kandhavelu

ASN In The Loop: “Disparities in the Use of Sodium Glucose Co-transporter 2 Inhibitors and Glucagon-like Peptie-1 Receptor Agonist in Adults with Chronic Kidney Disease”, Susanne B. Nicholas, Radica Alicic, and Jenny Shen

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Organ-Based Proteome and Post-Translational Modification Profiling of a Widely Cultivated Tropical Water Fish, Labeo rohita, Mehar Un Nissa, Nevil Pinto, Arijit Mukherjee, Panga Jaipal Reddy, Biplab Ghosh, Zhi Sun, Saicharan Ghantasala, Chetanya Chetanya, Sanjyot Vinayak Shenoy, Robert L Moritz, Mukunda Goswami, and Sanjeeva Srivastava

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The PeptideAtlas of a widely cultivated fish Labeo rohita: A resource for the Aquaculture Community., Mehar Un Nissa, Panga Jaipal Reddy, Nevil Pinto, Zhi Sun, Biplab Ghosh, Robert L Moritz, Mukunda Goswami, and Sanjeeva Srivastava

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mHealth-community health worker telemedicine intervention for surgical site infection diagnosis: a prospective study among women delivering via caesarean section in rural Rwanda., Theoneste Nkurunziza, Wendy Williams, Fredrick Kateera, Robert Riviello, Anne Niyigena, Elizabeth Miranda, Laban Bikorimana, Jonathan Nkurunziza, Lotta Velin, Andrea S Goodman, Alex Matousek, Stefanie J Klug, Erick Gaju, and Bethany L Hedt-Gauthier

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Anterior vs Posterior Approach in Multilevel Cervical Spondylotic Myelopathy: A Nationwide Propensity-Matched Analysis of Complications, Outcomes, and Narcotic Use., Ravi S Nunna, Syed Khalid, Ryan G Chiu, Rown Parola, Richard G Fessler, Owoicho Adogwa, and Ankit I Mehta

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The complete sequence of a human genome., Sergey Nurk, Sergey Koren, Arang Rhie, Mikko Rautiainen, Andrey V Bzikadze, Alla Mikheenko, Mitchell R Vollger, Nicolas Altemose, Lev Uralsky, Ariel Gershman, Sergey Aganezov, Savannah J Hoyt, Mark Diekhans, Glennis A Logsdon, Michael Alonge, Stylianos E Antonarakis, Matthew Borchers, Gerard G Bouffard, Shelise Y Brooks, Gina V Caldas, Nae-Chyun Chen, Haoyu Cheng, Chen-Shan Chin, William Chow, Leonardo G de Lima, Philip C Dishuck, Richard Durbin, Tatiana Dvorkina, Ian T Fiddes, Giulio Formenti, Robert S Fulton, Arkarachai Fungtammasan, Erik Garrison, Patrick G S Grady, Tina A Graves-Lindsay, Ira M Hall, Nancy F Hansen, Gabrielle A Hartley, Marina Haukness, Kerstin Howe, Michael W Hunkapiller, Chirag Jain, Miten Jain, Erich D Jarvis, Peter Kerpedjiev, Melanie Kirsche, Mikhail Kolmogorov, Jonas Korlach, Milinn Kremitzki, Heng Li, Valerie V Maduro, Tobias Marschall, Ann M McCartney, Jennifer McDaniel, Danny E Miller, James C Mullikin, Eugene W Myers, Nathan D Olson, Benedict Paten, Paul Peluso, Pavel A Pevzner, David Porubsky, Tamara Potapova, Evgeny I Rogaev, Jeffrey A Rosenfeld, Steven L Salzberg, Valerie A Schneider, Fritz J Sedlazeck, Kishwar Shafin, Colin J Shew, Alaina Shumate, Ying Sims, Arian F A Smit, Daniela C Soto, Ivan Sović, Jessica Storer, Aaron Streets, Beth A Sullivan, Françoise Thibaud-Nissen, James Torrance, Justin Wagner, Brian P Walenz, Aaron Wenger, Jonathan M D Wood, Chunlin Xiao, Stephanie M Yan, Alice C Young, Samantha Zarate, Urvashi Surti, Rajiv C McCoy, Megan Y Dennis, Ivan A Alexandrov, Jennifer L Gerton, Rachel J O'Neill, Winston Timp, Justin M Zook, Michael C Schatz, Evan E Eichler, Karen H Miga, and Adam M Phillippy

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Safety and antitumor activity of dostarlimab in patients with advanced or recurrent DNA mismatch repair deficient/microsatellite instability-high (dMMR/MSI-H) or proficient/stable (MMRp/MSS) endometrial cancer: interim results from GARNET-a phase I, single-arm study., Ana Oaknin, Lucy Gilbert, Anna V Tinker, Jubilee Brown, Cara Mathews, Joshua Press, Renaud Sabatier, David M O'Malley, Vanessa Samouelian, Valentina Boni, Linda Duska, Sharad Ghamande, Prafull Ghatage, Rebecca Kristeleit, Charles Leath Iii, Wei Guo, Ellie Im, Sybil Zildjian, Xinwei Han, Tao Duan, Jennifer Veneris, and Bhavana Pothuri

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Prospective Cohort Study of Psoriatic Arthritis Risk in Patients With Psoriasis in a Real-World Psoriasis Registry., Alexis Ogdie, Ryan W Harrison, Robert R McLean, Tin-Chi Lin, Mark Lebwohl, Bruce E Strober, Joe Zhuo, Vardhaman Patel, and Philip J Mease

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Challenges in the Diagnosis and Assessment of Psoriatic Arthritis., Alexis Ogdie, Christine A Lindsay, Philip Mease, Kristina Callis Duffin, Cheryl F Rosen, and Stefan Siebert

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Surgeon feedback to decrease opioid prescriptions after pediatric appendectomy., Kristin Ohe, Edward Hagen, Amber May, Mansen Wang, and Robert Weinsheimer

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A Propensity-Matched Comparison of the Perioperative Outcomes Between Single-Port and Multi-Port Robotic Assisted Partial Nephrectomy: A Report from the Single Port Advanced Research Consortium (SPARC)., Kennedy E Okhawere, Alp Tuna Beksac, Michael P Wilson, Talia G Korn, Kirolos N Meilika, Robert Harrison, Luca Morgantini, Mutahar Ahmed, Reza Mehrazin, Ronney Abaza, Daniel D Eun, Akshay Bhandari, Ashok K Hemal, James R Porter, Michael D Stifelman, Jihad Kaouk, Simone Crivellaro, and Ketan K Badani

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A comparison of outcomes between transperitoneal and retroperitoneal robotic assisted partial nephrectomy in patients with completely endophytic kidney tumors., Kennedy E Okhawere, Jordan Miller Rich, Burak Ucpinar, Alp Tuna Beksac, Indu Saini, Anthony Deluxe, Laura Zuluaga, Daniel D Eun, Akshay Bhandari, Ashok K Hemal, James Porter, Ronney Abaza, Ahmed Mansour, Michael D Stifelman, Simone Crivellaro, Phillip M Pierorazio, Osama Zaytoun, and Ketan K Badani

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Dimethyl Fumarate Delays Multiple Sclerosis in Radiologically Isolated Syndrome., Darin T Okuda, Orhun Kantarci, Christine Lebrun-Frénay, Maria Pia Sormani, Christina J Azevedo, Francesca Bovis, Le H Hua, Lilyana Amezcua, Ellen M Mowry, Christophe Hotermans, Jason Mendoza, John S Walsh, Christian von Hehn, Wendy S Vargas, Stacy Donlon, Robert T Naismith, Annette Okai, Gabriel Pardo, Pavle Repovic, Olaf Stüve, Aksel Siva, and Daniel Pelletier

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Repeat Revascularization Post Coronary Artery Bypass Grafting: Comparing Minimally Invasive and Traditional Sternotomy Techniques in 1468 Cases., Peter Olson, Michael Cinelli, Hamfreth S Rahming, Thomas Vazzana, Jonathan Spagnola, Emad Barsoum, Marc Assaad, Frank Tamburrino, and James Lafferty

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The 2022 Report on the Human Proteome from the HUPO Human Proteome Project., Gilbert S Omenn, Lydie Lane, Christopher M Overall, Charles Pineau, Nicolle H Packer, Ileana M Cristea, Cecilia Lindskog, Susan T Weintraub, Sandra Orchard, Michael H A Roehrl, Edouard Nice, Siqi Liu, Nuno Bandeira, Yu-Ju Chen, Tiannan Guo, Ruedi Aebersold, Robert L Moritz, and Eric W Deutsch

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Personal Dense Dynamic Data Clouds Connect Systems Biomedicine to Scientific Wellness., Gilbert S Omenn, Andrew T Magis, Nathan D Price, and Leroy Hood

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Effect of tofacitinib on dactylitis and patient-reported outcomes in patients with active psoriatic arthritis: post-hoc analysis of phase III studies., Ana-Maria Orbai, Philip J Mease, Philip S Helliwell, Oliver FitzGerald, Dona L Fleishaker, Rajiv Mundayat, and Pamela Young

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The Role of Parenteral Dantrolene in the Contemporary Management of Cerebral Vasospasm in Aneurysmal Subarachnoid Hemorrhage: A Systematic Review., Michael Ortiz, Ravi S Nunna, Kaushik Ravipati, Angela Tran, Adnan I Qureshi, and Farhan Siddiq

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Handedness and Specimen Chirality Affect Resident Upper Extremity Motion Patterns During Arthroscopic Simulation, Joseph O'Sullivan, Adam Rosencrans, Taylor Kong, Alexandra Bray, Carolin Curtze, Andrea Herzka, Dennis Crawford, and Jacqueline Brady

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ToPP: Tumor online prognostic analysis platform for prognostic feature selection and clinical patient subgroup selection., Jian Ouyang, Guangrong Qin, Zhenhao Liu, Xingxing Jian, Tieliu Shi, and Lu Xie

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Effect of sodium phenylbutyrate/taurursodiol on tracheostomy/ventilation-free survival and hospitalisation in amyotrophic lateral sclerosis: long-term results from the CENTAUR trial., Sabrina Paganoni, Suzanne Hendrix, Samuel P Dickson, Newman Knowlton, James D Berry, Michael Elliott, Samuel Maiser, Chafic Karam, James B Caress, Margaret Ayo Owegi, Adam Quick, James Wymer, Stephen A Goutman, Daragh Heitzman, Terry D Heiman-Patterson, Carlayne Jackson, Colin Quinn, Jeffrey D Rothstein, Edward J Kasarskis, Jonathan Katz, Liberty Jenkins, Shafeeq S Ladha, Timothy M Miller, Stephen N Scelsa, Tuan H Vu, Christina Fournier, Kristin M Johnson, Andrea Swenson, Namita Goyal, Gary L Pattee, Suma Babu, Marianne Chase, Derek Dagostino, Meghan Hall, Gale Kittle, Mathew Eydinov, Joseph Ostrow, Lindsay Pothier, Rebecca Randall, Jeremy M Shefner, Alexander V Sherman, Eric Tustison, Prasha Vigneswaran, Hong Yu, Joshua Cohen, Justin Klee, Rudolph Tanzi, Walter Gilbert, Patrick Yeramian, and Merit Cudkowicz

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Zandelisib with continuous or intermittent dosing as monotherapy or in combination with rituximab in patients with relapsed or refractory B-cell malignancy: a multicentre, first-in-patient, dose-escalation and dose-expansion, phase 1b trial., John M Pagel, Jacob D Soumerai, Nishitha Reddy, Deepa Jagadeesh, Anastasios Stathis, Adam Asch, Huda Salman, Vaishalee P Kenkre, Alexia Iasonos, Judith Llorin-Sangalang, Joanne Li, and Andrew D Zelenetz

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Validation of Consumer Activity Monitors in Postoperative Total Arthroplasty Patients, Joshuel A. Pahang and David B. Auyong

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Associations between SARS-CoV-2 variants and risk of COVID-19 hospitalization among confirmed cases in Washington State: a retrospective cohort study., Miguel I Paredes, Stephanie M Lunn, Michael Famulare, Lauren A Frisbie, Ian Painter, Roy Burstein, Pavitra Roychoudhury, Hong Xie, Shah A Mohamed Bakhash, Ricardo Perez, Maria Lukes, Sean Ellis, Saraswathi Sathees, Patrick C Mathias, Alexander Greninger, Lea M Starita, Chris D Frazar, Erica Ryke, Weizhi Zhong, Luis Gamboa, Machiko Threlkeld, Jover Lee, Evan McDermot, Melissa Truong, Deborah A Nickerson, Daniel L Bates, Matthew E Hartman, Eric Haugen, Truong N Nguyen, Joshua D Richards, Jacob L Rodriguez, John A Stamatoyannopoulos, Eric Thorland, Geoff Melly, Philip E Dykema, Drew C MacKellar, Hannah K Gray, Avi Singh, JohnAric M Peterson, Denny Russell, Laura Marcela Torres, Scott Lindquist, Trevor Bedford, Krisandra J Allen, and Hanna N Oltean

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An inactivated multivalent influenza A virus vaccine is broadly protective in mice and ferrets., Jaekeun Park, Sharon L Fong Legaspi, Louis M Schwartzman, Sebastian M Gygli, Zhong-Mei Sheng, Ashley D Freeman, Lex M Matthews, Yongli Xiao, Mitchell D Ramuta, Natalia A Batchenkova, Li Qi, Luz Angela Rosas, Stephanie L Williams, Kelsey Scherler, Monica Gouzoulis, Ian Bellayr, David M Morens, Kathie-Anne Walters, Matthew J Memoli, John C Kash, and Jeffery K Taubenberger

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A single-cell based precision medicine approach using glioblastoma patient-specific models., James H Park, Abdullah H Feroze, Samuel N Emerson, Anca B Mihalas, C Dirk Keene, Patrick J Cimino, Adrian Lopez Garcia de Lomana, Kavya Kannan, Wei-Ju Wu, Serdar Turkarslan, Nitin S Baliga, and Anoop P Patel

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Examination of the Economic Burden of Frailty in Patients With Adult Spinal Deformity Undergoing Surgical Intervention., Peter G Passias, Waleed Ahmad, Nicholas Kummer, Renaud Lafage, Virginie Lafage, Khaled Kebaish, Alan Daniels, Eric Klineberg, Alex Soroceanu, Jeffrey Gum, Breton Line, Robert A Hart, Douglas Burton, Robert Eastlack, Amit Jain, Justin S Smith, Christopher P Ames, Christopher Shaffrey, Frank Schwab, Richard Hostin, and Shay Bess

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Development of Risk Stratification Predictive Models for Cervical Deformity Surgery., Peter G Passias, Waleed Ahmad, Cheongeun Oh, Bailey Imbo, Sara Naessig, Katherine Pierce, Virginie Lafage, Renaud Lafage, D Kojo Hamilton, Themistocles S Protopsaltis, Eric O Klineberg, Jeffrey Gum, Andrew J Schoenfeld, Breton Line, Robert A Hart, Douglas C Burton, Shay Bess, Frank J Schwab, Justin S Smith, Christopher I Shaffrey, Christopher P Ames, and International Spine Study Group

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Changes in health-related quality of life measures associated with degree of proximal junctional kyphosis., Peter G Passias, Nicholas J Frangella, Tyler K Williamson, Kevin A Moattari, Renaud Lafage, Virginie Lafage, Justin S Smith, Khaled M Kebaish, Douglas C Burton, Robert A Hart, Christopher P Ames, Shay Bess, Christopher I Shaffrey, and Frank J Schwab

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Evolution of Adult Cervical Deformity Surgery Clinical and Radiographic Outcomes Based on a Multicenter Prospective Study: Are Behaviors and Outcomes Changing with Experience?, Peter G Passias, Oscar Krol, Kevin Moattari, Tyler K Williamson, Virginie Lafage, Renaud Lafage, Han Jo Kim, Alan Daniels, Bassel Diebo, Themistocles Protopsaltis, Gregory Mundis, Khaled Kebaish, Alexandra Soroceanu, Justin Scheer, D Kojo Hamilton, Eric Klineberg, Andrew J Schoenfeld, Shaleen Vira, Breton Line, Robert Hart, Douglas C Burton, Frank A Schwab, Christopher Shaffrey, Shay Bess, Justin S Smith, Christopher P Ames, and International Spine Study Group

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The Benefit of Addressing Malalignment In Revision Surgery for Proximal Junctional Kyphosis Following ASD Surgery., Peter G Passias, Oscar Krol, Tyler K Williamson, Virginie Lafage, Renaud Lafage, Justin S Smith, Breton Line, Shaleen Vira, Shaina Lipa, Alan Daniels, Bassel Diebo, Andrew Schoenfeld, Jeffrey Gum, Khaled Kebaish, Paul Park, Gregory Mundis, Richard Hostin, Manush Gupta, Robert Eastlack, Neel Anand, Christopher Ames, Robert A Hart, Douglas Burton, Frank J Schwab, Christopher Shaffrey, Eric Klineberg, and Shay Bess

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Improvements in Outcomes and Cost after Adult Spinal Deformity Corrective Surgery between 2008 and 2019., Peter G Passias, Nicholas Kummer, Bailey Imbo, Virginie Lafage, Renaud Lafage, Justin S Smith, Breton Line, Shaleen Vira, Andrew J Schoenfeld, Jeffrey L Gum, Alan H Daniels, Eric O Klineberg, Munish C Gupta, Khaled M Kebaish, Amit Jain, Brian J Neuman, Dean Chou, Leah Y Carreon, Robert A Hart, Douglas C Burton, Christopher I Shaffrey, Christopher P Ames, Frank J Schwab, Richard A Hostin, Shay Bess, and International Spine Study Group

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The Additional Economic Burden of Frailty in Adult Cervical Deformity Patients Undergoing Surgical Intervention., Peter G Passias, Nicholas Kummer, Tyler K Williamson, Waleed Ahmad, Jordan Lebovic, Virginie Lafage, Renaud Lafage, Han Jo Kim, Alan H Daniels, Jeffrey L Gum, Bassel G Diebo, Munish C Gupta, Alexandra Soroceanu, Justin K Scheer, D Kojo Hamilton, Eric O Klineberg, Breton Line, Andrew J Schoenfeld, Robert A Hart, Douglas C Burton, Robert K Eastlack, Gregory M Mundis, Praveen Mummaneni, Dean Chou, Paul Park, Frank J Schwab, Christopher I Shaffrey, Shay Bess, Christopher P Ames, Justin S Smith, and International Spine Study Group

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Highest Achievable Outcomes for Patients Undergoing Cervical Deformity Corrective Surgery by Frailty., Peter G Passias, Nicholas Kummer, Tyler K Williamson, Kevin Moattari, Virginie Lafage, Renaud Lafage, Han Jo Kim, Alan H Daniels, Jeffrey L Gum, Bassel G Diebo, Themistocles S Protopsaltis, Gregory M Mundis, Robert K Eastlack, Alexandra Soroceanu, Justin K Scheer, D Kojo Hamilton, Eric O Klineberg, Breton Line, Robert A Hart, Douglas C Burton, Praveen Mummaneni, Dean Chou, Paul Park, Frank J Schwab, Christopher I Shaffrey, Shay Bess, Christopher P Ames, and Justin S Smith

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Establishment of an Individualized Distal Junctional Kyphosis Risk Index following the Surgical Treatment of Adult Cervical Deformities., Peter G Passias, Sara Naessig, Navraj Sagoo, Lara Passfall, Waleed Ahmad, Renaud Lafage, Virginie Lafage, Shaleen Vira, Andrew J Schoenfeld, Cheongeun Oh, Themistocles Protopsaltis, Han Jo Kim, Alan Daniels, Robert A Hart, Douglas Burton, Eric O Klineberg, Shay Bess, Frank Schwab, Christopher Shaffrey, Christopher P Ames, Justin S Smith, and International Spine Study Group

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Pelvic Non-Response Following Treatment of Adult Spinal Deformity: Influence of Realignment Strategies on Occurrence., Peter G Passias, Katherine E Pierce, Tyler K Williamson, Oscar Krol, Renaud Lafage, Virginie Lafage, Andrew J Schoenfeld, Themistocles S Protopsaltis, Shaleen Vira, Breton Line, Bassel G Diebo, Christopher P Ames, Han Jo Kim, Justin S Smith, Dean Chou, Alan H Daniels, Jeffrey L Gum, Christopher I Shaffrey, Douglas C Burton, Michael P Kelly, Eric O Klineberg, Robert A Hart, Shay Bess, Frank J Schwab, and Munish C Gupta

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Predictive Analytics for Determining Extended Operative Time in Corrective Adult Spinal Deformity Surgery., Peter G Passias, Gregory W Poorman, Dennis Vasquez-Montes, Nicholas Kummer, Gregory Mundis, Neel Anand, Samantha R Horn, Frank A Segreto, Lara Passfall, Oscar Krol, Bassel Diebo, Doug Burton, Aaron Buckland, Michael Gerling, Alex Soroceanu, Robert Eastlack, D Kojo Hamilton, Robert A Hart, Frank Schwab, Virginie Lafage, Christopher Shaffrey, Daniel Sciubba, Shay Bess, Christopher Ames, Eric Klineberg, and International Spine Study Group

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Is frailty responsive to surgical correction of adult spinal deformity? An investigation of sagittal re-alignment and frailty component drivers of postoperative frailty status., Peter G Passias, Frank A Segreto, Kevin A Moattari, Renaud Lafage, Justin S Smith, Breton G Line, Robert K Eastlack, Douglas C Burton, Robert A Hart, Shay Bess, Christopher I Shaffrey, Christopher P Ames, Virginie Lafage, and International Spine Study Group

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Posterior Ischemic Optic Neuropathy Because of Hematologic Malignancy., Ankush U Patel, Uresh S Patel, and Eugene F May

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Clinical and radiographic benefits of skipping C7 instrumentation in posterior cervicothoracic fusion: a retrospective analysis., Saavan Patel, Morteza Sadeh, Matthew K Tobin, Nauman S Chaudhry, C Gragnaniello, and Sergey Neckrysh

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Factors associated with poor outcomes among COVID-19 patients with gastrointestinal symptoms., Nikita Patil, Pankush Kalgotra, Suneha Sundaram, Stephanie Melquist, Sravanthi Parasa, Madhav Desai, and Prateek Sharma

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Duty to Warn Notifications in Residency Training, Savannah Patterson and Kelly Wurzel

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Reconsidering the in vivo functions of Clostridial Stickland amino acid fermentations., Aidan Pavao, Madeline Graham, Mario L Arrieta-Ortiz, Selva Rupa Christinal Immanuel, Nitin S Baliga, and Lynn Bry

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Reducing Eating Disorder Risk Among Male Athletes: A Randomized Controlled Trial Investigating the Male Athlete Body Project., Hayley Perelman, Natalie Schwartz, Jennifer Yeoward-Dodson, Isabel C Quiñones, Matthew F Murray, Elizabeth N Dougherty, Raven Townsel, Jessyca Arthur-Cameselle, and Alissa A Haedt-Matt

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Durability of High-Frequency 10-kHz Spinal Cord Stimulation for Patients With Painful Diabetic Neuropathy Refractory to Conventional Treatments: 12-Month Results From a Randomized Controlled Trial., Erika A Petersen, Thomas G Stauss, James A Scowcroft, Elizabeth S Brooks, Judith L White, Shawn M Sills, Kasra Amirdelfan, Maged N Guirguis, Jijun Xu, Cong Yu, Ali Nairizi, Denis G Patterson, Kostandinos C Tsoulfas, Michael J Creamer, Vincent Galan, Richard H Bundschu, Neel D Mehta, Dawood Sayed, Shivanand P Lad, David J DiBenedetto, Khalid A Sethi, Johnathan H Goree, Matthew T Bennett, Nathan J Harrison, Atef F Israel, Paul Chang, Paul W Wu, Charles E Argoff, Christian E Nasr, Rod S Taylor, David L Caraway, and Nagy A Mekhail

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High-Frequency 10-kHz Spinal Cord Stimulation Improves Health-Related Quality of Life in Patients With Refractory Painful Diabetic Neuropathy: 12-Month Results From a Randomized Controlled Trial., Erika A Petersen, Thomas G Stauss, James A Scowcroft, Elizabeth S Brooks, Judith L White, Shawn M Sills, Kasra Amirdelfan, Maged N Guirguis, Jijun Xu, Cong Yu, Ali Nairizi, Denis G Patterson, Kostandinos C Tsoulfas, Michael J Creamer, Vincent Galan, Richard H Bundschu, Neel D Mehta, Dawood Sayed, Shivanand P Lad, David J DiBenedetto, Khalid A Sethi, Johnathan H Goree, Matthew T Bennett, Nathan J Harrison, Atef F Israel, Paul Chang, Paul W Wu, Charles E Argoff, Christian E Nasr, Rod S Taylor, David L Caraway, and Nagy A Mekhail

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The effect of COVID-19 vaccination and booster on maternal-fetal outcomes: a retrospective multicenter cohort study., Samantha N Piekos, Yeon Mi Hwang, Ryan Roper, Tanya K Sorensen, Nathan D Price, Leroy Hood, and Jennifer J Hadlock

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The impact of maternal SARS-CoV-2 infection and COVID-19 vaccination on maternal-fetal outcomes., Samantha N Piekos, Nathan D Price, Leroy Hood, and Jennifer J Hadlock

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The effect of maternal SARS-CoV-2 infection timing on birth outcomes: a retrospective multicentre cohort study., Samantha N Piekos, Ryan Roper, Yeon Mi Hwang, Tanya K Sorensen, Nathan D Price, Leroy Hood, and Jennifer J Hadlock

Design and Implementation of a Decentralized Virtual Molecular Tumor Board across a Large, Diverse Community Health System, Brian Piening, Patrick Foley, K Matlock, H Wright, Lauren Harold, Roshanthi Weerasinghe, A Viita, C Moung-Wen, Jacob Abel, Vassil Kaimaktchiev, A Dowdell, Ryan Meng, Walter Urba, G Srinivasa, Philip Gold, Gina Vaccaro, and Carlo Bifulco

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ALSUntangled #66: antimycobacterial antibiotics., Ellen S Pierce, Paul Barkhaus, Morgan Beauchamp, Mark Bromberg, Gregory T Carter, Jill Goslinga, David Greeley, Sky Kihuwa-Mani, Gleb Levitsky, Isaac Lund, Christopher McDermott, Gary Pattee, Kaitlyn Pierce, Meraida Polak, Dylan Ratner, Paul Wicks, and Richard Bedlack

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Uncovering potential interventions for pancreatic cancer patients via mathematical modeling., Daniel Plaugher, Boris Aguilar, and David Murrugarra

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An Assessment of the Safety of Surgery and Hardware Placement in de-novo Spinal Infections. A Systematic Review and Meta-Analysis of the Literature., Jonathan Pluemer, Yevgeniy Freyvert, Nathan Pratt, Jerry E Robinson, Jared A Cooke, Zachary L Tataryn, Periklis Godolias, Zeyad A Daher, Rod J Oskouian, and Jens R Chapman

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The effect of race on treatment patterns and subsequent health-related quality of life outcomes in men undergoing treatment for localized prostate cancer., Natasza M Posielski, Santosh Shanmuga, On Ho, Jiji Jiang, Sally Elsamanoudi, Ryan Speir, Sean Stroup, John Musser, Alexander Ernest, Gregory T Chesnut, Timothy Tausch, John Paul Flores, and Christopher Porter

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A Functional Module States Framework Reveals Transcriptional States for Drug and Target Prediction., Guangrong Qin, Theo A Knijnenburg, David L Gibbs, Russell Moser, Raymond J Monnat, Christopher J Kemp, and Ilya Shmulevich

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Gender, Race, and Ethnicity Representation Among Gastroenterologists: A Review of Recent Trends., Harman Rahal, Mohit Girotra, Folasade P May, and James H Tabibian

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Transseptal puncture during catheter ablation associated with higher radiation exposure., Maryam Rahman, Grace Smith, Chris Johnsrude, Martin LaPage, Jeremy Moore, Kevin Shannon, Chris Anderson, John Papagiannis, Kelvin Lau, Shubhayan Sanatani, Mansour Razminia, Volkan Tuzcu, David Gothard, Lisa Shauver, and John Clark

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Method for Independent Estimation of the False Localization Rate for Phosphoproteomics., Kerry A Ramsbottom, Ananth Prakash, Yasset Perez Riverol, Oscar Martin Camacho, Maria-Jesus Martin, Juan Antonio Vizcaíno, Eric W Deutsch, and Andrew R Jones

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Changing the Trajectory of Heart Failure and Kidney Disease: A Call for Action., Janani Rangaswami, Vivek Bhalla, Glenn M Chertow, Robert A Harrington, Alexander Staruschenko, Katherine Tuttle, and Eugene Braunwald

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Pharmacologic Pain Management Trends among Adults Hospitalized with Cellulitis: An Evidence-Based Practice Project., Teresa Rangel, Sydney Pham, Brenda Senger, Kristopher Daratha, Cynthia Fitzgerald, Rebecca Mallo, and Kenneth Daratha

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PTPRD and CNTNAP2 as markers of tumor aggressiveness in oligodendrogliomas., Kirsi J Rautajoki, Serafiina Jaatinen, Aliisa M Tiihonen, Matti Annala, Elisa M Vuorinen, Anni Kivinen, Minna J Rauhala, Kendra K Maass, Kristian W Pajtler, Olli Yli-Harja, Pauli Helén, Joonas Haapasalo, Hannu Haapasalo, Wei Zhang, and Matti Nykter

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Saving time and money: Modernizing a computer-based learning assignment process., Rachelle Reid, Mitch Hartly, and Charles K Perkins

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Novel approaches to hypoglycemia and burnt-out diabetes in chronic kidney disease., Connie M Rhee, Kamyar Kalantar-Zadeh, and Katherine Tuttle

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Novel approaches to hypoglycemia and burnt-out diabetes in chronic kidney disease., Connie M Rhee, Kamyar Kalantar-Zadeh, and Katherine Tuttle

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Odds of Hospitalization for COVID-19 After 3 vs 2 Doses of mRNA COVID-19 Vaccine by Time Since Booster Dose., Jessica P Ridgway, Samuel Tideman, Tom French, Bill J. Wright, Guilford Parsons, George Diaz, and Ari Robicsek

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Rates of COVID-19 Among Unvaccinated Adults With Prior COVID-19., Jessica P Ridgway, Samuel Tideman, Bill J. Wright, and Ari Robicsek

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Decreased Risk of Coronavirus Disease 2019-Related Hospitalization Associated With the Omicron Variant of Severe Acute Respiratory Syndrome Coronavirus 2., Jessica P Ridgway, Samuel Tideman, Bill Wright, and Ari Robicsek

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Inflammation drives residual risk in chronic kidney disease: a CANTOS substudy., Paul M Ridker, Katherine Tuttle, Vlado Perkovic, Peter Libby, and Jean G MacFadyen

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Inflammation drives residual risk in chronic kidney disease: a CANTOS substudy., Paul M Ridker, Katherine R Tuttle, Vlado Perkovic, Peter Libby, and Jean G MacFadyen

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Splenic vein aneurysm: Case report of an exceedingly rare condition, Dave Riesberg

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Discovery and Visualization of Uncharacterized Drug-Protein Adducts Using Mass Spectrometry., Michael Riffle, Michael R Hoopmann, Daniel Jaschob, Guo Zhong, Robert L Moritz, Michael J MacCoss, Trisha N Davis, Nina Isoherranen, and Alex Zelter

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Sustained and improved guselkumab response in patients with active psoriatic arthritis regardless of baseline demographic and disease characteristics: pooled results through week 52 of two phase III, randomised, placebo-controlled studies., Christopher T Ritchlin, Philip Mease, Wolf-Henning Boehncke, John Tesser, Elena Schiopu, Soumya D Chakravarty, Alexa P Kollmeier, Xie L Xu, May Shawi, Yusang Jiang, Shihong Sheng, Yanli Wang, Stephen Xu, Joseph F Merola, Iain B McInnes, and Atul Deodhar

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The Coaching for Cognition in Alzheimer's (COCOA) trial: Study design., Jared C Roach, Junko Hara, Deborah Fridman, Jennifer C Lovejoy, Kathleen Jade, Laura Heim, Rachel Romansik, Adrienne Swietlikowski, Sheree Phillips, Molly Rapozo, Maria A Shay, Dan Fischer, Cory C Funk, Lauren Dill, Michael Brant-Zawadzki, Leroy Hood, and William R Shankle

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Dense data enables 21th century clinical trials., Jared C Roach, John F Hodes, Cory C Funk, William R Shankle, David A Merrill, Leroy Hood, and Jennifer Bramen

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Quality control of large genome datasets., Max Robinson, Arpita Joshi, Ansh Vidyarthi, Mary Maccoun, Sanjay Rangavajjhala, and Gustavo Glusman

A Mindfulness Program to Reduce Compassion Fatigue and Burnout in Nurses, Teresa Robinson, Angela Hamel, and Kathy Christensen

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The hiatus between organism and machine evolution: Contrasting mixed microbial communities with robots., Andrea Roli and Stuart A Kauffman

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Influence of a Formal Mentor on Hospital based Nurse Research Resources and Outcomes, Jamie Roney, Trisha Saul, Teresa Bigand, Marietta Sperry, Carrie Doyle, and Sherri Mendelson

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Gene-gene interaction of AhRwith and within the Wntcascade affects susceptibility to lung cancer., Albert Rosenberger, Nils Muttray, Rayjean J Hung, David C Christiani, Neil E Caporaso, Geoffrey Liu, Stig E Bojesen, Loic Le Marchand, Demetrios Albanes, Melinda C Aldrich, Adonina Tardon, Guillermo Fernández-Tardón, Gad Rennert, John K Field, Michael P A Davies, Triantafillos Liloglou, Lambertus A Kiemeney, Philip Lazarus, Bernadette Wendel, Aage Haugen, Shanbeh Zienolddiny, Stephen Lam, Matthew B Schabath, Angeline S Andrew, Eric J Duell, Susanne M Arnold, Gary E Goodman, Chu Chen, Jennifer A Doherty, Fiona Taylor, Angela Cox, Penella J Woll, Angela Risch, Thomas R Muley, Mikael Johansson, Paul Brennan, Maria Teresa Landi, Sanjay S Shete, Christopher I Amos, and Heike Bickeböller

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Executive summary of the KDIGO 2022 Clinical Practice Guideline for Diabetes Management in Chronic Kidney Disease: an update based on rapidly emerging new evidence., Peter Rossing, M Luiza Caramori, Juliana C N Chan, Hiddo J L Heerspink, Clint Hurst, Kamlesh Khunti, Adrian Liew, Erin D Michos, Sankar D Navaneethan, Wasiu A Olowu, Tami Sadusky, Nikhil Tandon, Katherine Tuttle, Christoph Wanner, Katy G Wilkens, Sophia Zoungas, Jonathan C Craig, David J Tunnicliffe, Marcello A Tonelli, Michael Cheung, Amy Earley, and Ian H de Boer

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Baseline risk markers and visit-to-visit variability in relation to kidney outcomes - A post-hoc analysis of the PERL study., Viktor Rotbain Curovic, Neil Roy, Tine W Hansen, M Luiza Caramori, David Z Cherney, Ian H De Boer, Mary Ann Emanuele, Irl B Hirsch, Ildiko Lingvay, Janet B Mcgill, Sarit Polsky, Rodica Pop-Busui, Ronald J Sigal, Katherine R Tuttle, Guillermo E Umpierrez, Amisha Wallia, Sylvia E Rosas, Peter Rossing, and PERL Study Group

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Uterine Sarcomas: How to Navigate an Ever-Growing List of Subtypes., Molly Roy, Fernanda Musa, Sarah E Taylor, and Marilyn Huang

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Contemporary Anesthetic Evaluation and Management for Electroconvulsive Therapy., Francis V Salinas

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Methicillin-resistant staphylococcus aureus nosocomial infection has a distinct epidemiological position and acts as a marker for overall hospital-acquired infection trends., Noelle I Samia, Ari Robicsek, Hans Heesterbeek, and Lance R Peterson