Providence research from Washington locations.

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Submissions from 2022

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A multi-institutional approach for decreasing narcotic prescriptions after laparoscopic appendectomy., Danielle Hayes, Mimi Tan, Mansen Wang, and Robert Weinsheimer

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Manifestations of Alzheimer's disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90., Laura M Heath, John C Earls, Andrew T Magis, Sergey A Kornilov, Jennifer C Lovejoy, Cory C Funk, Noa Rappaport, Benjamin A Logsdon, Lara M Mangravite, Brian W Kunkle, Eden R Martin, Adam C Naj, Nilüfer Ertekin-Taner, Todd E Golde, Leroy Hood, Nathan D Price, and Alzheimer’s Disease Genetics Consortium

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Telemedicine for Surgical Site Infection Diagnosis in Rural Rwanda: Concordance and Accuracy of Image Reviews., Bethany Hedt-Gauthier, Elizabeth Miranda, Theoneste Nkurunziza, Olivia Hughes, Adeline A Boatin, Erick Gaju, Alexi Matousek, Teena Cherian, Robert Riviello, and Fredrick Kateera

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Effects of tirzepatide versus insulin glargine on kidney outcomes in type 2 diabetes in the SURPASS-4 trial: post-hoc analysis of an open-label, randomised, phase 3 trial., Hiddo J L Heerspink, Naveed Sattar, Imre Pavo, Axel Haupt, Kevin L Duffin, Zhengyu Yang, Russell J Wiese, Katherine Tuttle, and David Z I Cherney

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Delayed mortality among solid organ transplant recipients hospitalized for COVID-19., Madeleine R Heldman, Olivia S Kates, Kassem Safa, Camille N Kotton, Ashrit Multani, Sarah J Georgia, Julie M Steinbrink, Barbara D Alexander, Emily A Blumberg, Brandy Haydel, Vagish Hemmige, Marion Hemmersbach-Miller, Ricardo M La Hoz, Lisset Moni, Yesabeli Condor, Sandra Flores, Carlos G Munoz, Juan Guitierrez, Esther I Diaz, Daniela Diaz, Rodrigo Vianna, Giselle Guerra, Matthias Loebe, Julie M Yabu, Kailey Hughes Kramer, Sajal D Tanna, Michael G Ison, Robert M Rakita, Maricar Malinis, Marwan M Azar, Margaret E McCort, Pooja P Singh, Arzu Velioglu, Sapna A Mehta, David van Duin, Jason D Goldman, Erika D Lease, Anna Wald, Ajit P Limaye, and Cynthia E Fisher

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Impact of clinical domains other than arthritis on composite outcomes in psoriatic arthritis: comparison of treatment effects in the SEAM-PsA trial., Philip S Helliwell, Philip Mease, Arthur Kavanaugh, Laura C Coates, Alexis Ogdie, Atul Deodhar, Vibeke Strand, Gregory Kricorian, Lyrica X H Liu, David Collier, and Dafna D Gladman

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Radiofrequency ablation in the management of primary hepatic and biliary tumors., Richard Hendriquez, Tara Keihanian, Jatinder Goyal, Rtika R Abraham, Rajnish Mishra, and Mohit Girotra

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Clinical Experiences of 3-Dimensional Biportal Endoscopic Spine Surgery for Lumbar Degenerative Disease., Dong Hwa Heo, Ji Yeon Kim, Jeong-Yoon Park, Jin Sung Kim, Hyeun Sung Kim, Jeffrey R Roh, Choon Keun Park, and Hungtae Chung

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Pulmonary Open, Robotic, and Thoracoscopic Lobectomy study: Outcomes and risk factors of conversion during minimally invasive lobectomy., Luis J Herrera, Lana Y Schumacher, Matthew G Hartwig, Charles T Bakhos, Rishindra M Reddy, Eric Vallieres, and Michael S Kent

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On evaluation metrics for medical applications of artificial intelligence., Steven A Hicks, Inga Strümke, Vajira Thambawita, Malek Hammou, Michael A Riegler, Pål Halvorsen, and Sravanthi Parasa

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P4 Medicine & What 21st Century Medicine Should Be, Leroy Hood

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Autocatalytic Sets Arising in a Combinatorial Model of Chemical Evolution., Wim Hordijk, Mike Steel, and Stuart Kauffman

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Family Medicine Resident Perceptions on Racial Justice Training in Residency: A CERA Study., Tiffany Ho, Bari Laskow, Alexandra Zaballa, and Gerardo Moreno

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POCUS Evaluation in Acute Kidney Injury, Vanessa Hoytfox, Brittney Ward, and Kang X Zhang

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From telomere to telomere: The transcriptional and epigenetic state of human repeat elements., Savannah J Hoyt, Jessica Storer, Gabrielle A Hartley, Patrick G S Grady, Ariel Gershman, Leonardo G de Lima, Charles Limouse, Reza Halabian, Luke Wojenski, Matias Rodriguez, Nicolas Altemose, Arang Rhie, Leighton J Core, Jennifer L Gerton, Wojciech Makalowski, Daniel Olson, Jeb Rosen, Arian F A Smit, Aaron F Straight, Mitchell R Vollger, Travis J Wheeler, Michael C Schatz, Evan E Eichler, Adam M Phillippy, Winston Timp, Karen H Miga, and Rachel J O'Neill

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A Wipe-Based Stool Collection and Preservation Kit for Microbiome Community Profiling., Hui Hua, Cem Meydan, Evan E Afshin, Loukia N Lili, Christopher R D'Adamo, Nate Rickard, Joel T Dudley, Nathan D Price, Bodi Zhang, and Christopher E Mason

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Towards a unification of the 2 meanings of "epigenetics"., Sui Huang

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Accuracy of multiple sequence alignment methods in the reconstruction of transposable element families., Robert Hubley, Travis J Wheeler, and Arian F A Smit

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Development and Validation of a Breast Cancer Polygenic Risk Score on the Basis of Genetic Ancestry Composition., Elisha Hughes, Susanne Wagner, Dmitry Pruss, Ryan Bernhisel, Braden Probst, Victor Abkevich, Timothy Simmons, Brooke Hullinger, Thaddeus Judkins, Eric Rosenthal, Benjamin Roa, Susan M Domchek, Charis Eng, Judy Garber, Monique Gary, Jennifer Klemp, Semanti Mukherjee, Kenneth Offit, Olufunmilayo I Olopade, Joseph Vijai, Jeffrey N Weitzel, Pat Whitworth, Lamis Yehia, Ora K Gordon, Holly Pederson, Allison Kurian, Thomas P Slavin, Alexander Gutin, and Jerry S Lanchbury

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Real-world evidence of a successful biosimilar adoption program., Sophia Z Humphreys

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Deletion of Abi3/Gngt2 influences age-progressive amyloid β and tau pathologies in distinctive ways., Kristen R Ibanez, Karen N McFarland, Jennifer Phillips, Mariet Allen, Christian B Lessard, Lillian Zobel, Elsa Gonzalez De La Cruz, Shivani Shah, Quan Vo, Xue Wang, Zachary Quicksall, Daniel Ryu, Cory C Funk, Nilüfer Ertekin-Taner, Stefan Prokop, Todd E Golde, and Paramita Chakrabarty

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Protein Catalyzed Capture (PCC) Agents for Antigen Targeting., Matthew N Idso, Bert T Lai, Heather D Agnew, and James R Heath

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A Blood-Based Metabolite Panel for Distinguishing Ovarian Cancer from Benign Pelvic Masses., Ehsan Irajizad, Chae Y Han, Joseph Celestino, Ranran Wu, Eunice Murage, Rachelle Spencer, Jennifer B Dennison, Jody Vykoukal, James P Long, Kim Anh Do, Charles Drescher, Karen Lu, Zhen Lu, Robert C Bast, Sam Hanash, and Johannes F Fahrmann

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Vasoplegia Following Complex Spine Surgery: Incidence and Risk., Basem Ishak, Juan N Pulido, Alexander von Glinski, Darius Ansari, Rod J Oskouian, and Jens R Chapman

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How to Give Less Bad News: A Guide to ALS Mimics - David Ivanick, MD, David Ivanick

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Cervical Spine Research Society-Cervical Stiffness Disability Index (CSRS-CSDI): Validation of a Novel Scoring System Quantifying the Effect of Postarthrodesis Cervical Stiffness on Patient Quality of Life., Andrew S Jack, Erik Hayman, Clifford Pierre, Wyatt L Ramey, Christopher D Witiw, Rod J Oskouian, Alan H Daniels, Andrew Pugley, Kojo Hamilton, Christopher P Ames, Jens R Chapman, Zoher Ghogawala, and Robert A Hart

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Effects of caloric restriction and aerobic exercise on circulating cell-free mitochondrial DNA in patients with moderate to severe chronic kidney disease., Javier Jaramillo-Morales, Berfu Korucu, Mindy M Pike, Loren Lipworth, Thomas Stewart, Samuel A E Headley, Michael Germain, Gwenaelle Begue, Baback Roshanravan, Katherine Tuttle, Jonathan Himmelfarb, Cassianne Robinson-Cohen, T Alp Ikizler, and Jorge L Gamboa

Delivering Value-Based Care at Scale-Best Practices for Birth and Beyond, Trina Jellison

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Agent-based computational modeling of glioblastoma predicts that stromal density is central to oncolytic virus efficacy., Adrianne L Jenner, Munisha Smalley, David Goldman, William F Goins, Charles Cobbs, Ralph B Puchalski, E Antonio Chiocca, Sean Lawler, Paul Macklin, Aaron Goldman, and Morgan Craig

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Comparison of 26-mm Evolut and 23-mm Sapien 3 Valves in TAVR for Small Aortic Annulus., Ruyun Jin, Emily J Cox, Branden Reynolds, Brydan Curtis, Robert W. Hodson, Michael Reed, Sameer Gafoor, Gary Grunkemeier, Matthew Forrester, and Michael Ring

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Using a Food Bank as a Platform for Educating Communities during the COVID-19 Pandemic., Xianglan Jin, Mabel Ezeonwu, Andreka Ayad, and Karen Bowman

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Is DIA proteomics data FAIR? Current data sharing practices, available bioinformatics infrastructure and recommendations for the future., Andrew R Jones, Eric W Deutsch, and Juan Antonio Vizcaíno

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Validation of the Foot and Ankle Outcome Score for Use in Infracalcaneal Heel Pain., Alisha Joshi, Christopher Collazo, Zachary Laidley, Erin E Klein, Lowell Weil, Matthew D Sorensen, and Adam E Fleischer

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The Novel Conduit: Challenges of Esophagectomy After Bariatric Surgery., Michael Jureller, Shankar I Logarajah, Travis Allen Van Meter, Housam Osman, John Jay, Maitham Moslim, Ralph W Aye, and D Rohan Jeyarajah

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Early Experience With New Femoral and Tibial Cones in Revision Total Knee Arthroplasty: A Case Series., Michael E Kahan, Joshua E Drumm, Zhongming Chen, Arthur L Malkani, Michael A Mont, Ronald E Delanois, and James Nace

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Profiling the Human Phosphoproteome to Estimate the True Extent of Protein Phosphorylation., Anton Kalyuzhnyy, Patrick A Eyers, Claire E Eyers, Emily Bowler-Barnett, Maria J Martin, Zhi Sun, Eric W Deutsch, and Andrew R Jones

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The validity, responsiveness, and score interpretation of the PROMISnq Physical Function - Multiple Sclerosis 15a short form in multiple sclerosis., Paul Kamudoni, Dagmar Amtmann, Jeffrey Johns, Karon F Cook, Rana Salem, Sam Salek, Jana Raab, Rod Middleton, P Repovic, Kevin N Alschuler, Gloria von Geldern, Annette Wundes, Amy Barrett, Oyebimpe Olayinka-Amao, and Christian Henke

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Fatty Kidney: A Possible Future for Chronic Kidney Disease Research., Mehmet Kanbay, Sidar Copur, Atalay Demiray, Alan A Sag, Adrian Covic, Alberto Ortiz, and Katherine Tuttle

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Cardiorenal Metabolic Consequences of Nighttime Snacking: Is it an Innocent Eating Behavior?, Mehmet Kanbay, Sidar Copur, Atalay Demiray, and Katherine Tuttle

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The risk for chronic kidney disease in metabolically healthy obese patients: A systematic review and meta-analysis., Mehmet Kanbay, Sidar Copur, Dimitrie Siriopol, Abdullah B Yildiz, Metehan Berkkan, Katherine Tuttle, and Carmine Zoccali

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Exploring Perinatal Nursing Care for Opioid Use Disorder: Knowledge, Stigma, and Compassion., Ira Kantrowitz-Gordon, Cynthia Price, Vania Rudolf, Georgia Downey, and Kelsey Castagnola

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Tyrosine kinase-altered spindle cell neoplasms with EGFR internal tandem duplications., Erica Kao, Navin Pinto, Angela Trobaugh-Lotrario, Gail H Deutsch, Yu Wu, Wenjing Wang, Erin R Rudzinski, and Yajuan J Liu

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PCM1-JAK2 Fusion Tyrosine Kinase Gene-Related Neoplasia: A Systematic Review of the Clinical Literature., Henry G Kaplan, Ruyun Jin, Carlo Bifulco, James M Scanlan, and David R Corwin

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Trastuzumab therapy duration in HER2-positive de novo metastatic breast cancer: 1999-2018, Henry Kaplan, Judith A. Malmgren, Boya Guo, and Mary K. Atwood

Reszinate—A Phase 1/2 Randomized Clinical Trial of Zinc and Resveratrol Utilizing Home Patient-Obtained Nasal and Saliva Viral Sampling, Henry Kaplan, Kai Wang, Kimberly M. Reeves, James Scanlan, Christopher C. Nunn, Douglas A. Kieper, Joshua L. Mark, Inyoul Lee, Rachel Liu, Ruyun Jin, Michael J. Bolton, and Jason D. Goldman

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Treatment of nonsurgical refractory back pain with high-frequency spinal cord stimulation at 10 kHz: 12-month results of a pragmatic, multicenter, randomized controlled trial., Leonardo Kapural, Jessica Jameson, Curtis Johnson, Daniel Kloster, Aaron Calodney, Peter Kosek, Julie Pilitsis, Markus Bendel, Erika Petersen, Chengyuan Wu, Taissa Cherry, Shivanand P Lad, Cong Yu, Dawood Sayed, Johnathan Goree, Mark K Lyons, Andrew Sack, Diana Bruce, Frances Rubenstein, Rose Province-Azalde, David Caraway, and Naresh P Patel

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Programmed cell death detection methods: a systematic review and a categorical comparison., Sana Kari, Kumar Subramanian, Ilenia Agata Altomonte, Akshaya Murugesan, Olli Yli-Harja, and Meenakshisundaram Kandhavelu

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Government Regulation and Percutaneous Coronary Intervention Volume, Access and Outcomes: Insights From the Washington State Cardiac Care Outcomes Assessment Program., Akash Kataruka, Charles C Maynard, Ravi S Hira, Larry Dean, Todd Dardas, Hitinder Gurm, Josiah Brown, Michael Ring, and Jacob A Doll

Implementing Goal-Directed Medical Therapies for Diabetic Kidney Disease: The Garabed Eknoyan MD, Endowed Lectureship, Tuttle Katherine

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A Testable Theory for the Emergence of the Classical World., Stuart Kauffman and Sudip Patra

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KDIGO 2022 Clinical Practice Guideline for Diabetes Management in Chronic Kidney Disease., Kidney Disease: Improving Global Outcomes (KDIGO) Diabetes Work Group and Katherine Tuttle

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Role of Endoscopic Retrograde Cholangiopancreatography in the Diagnosis and Management of Cholestatic Liver Diseases., Tara Keihanian, Monique T Barakat, Sooraj Tejaswi, Rajnish Mishra, Christopher J Carlson, John J Brandabur, and Mohit Girotra

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Identification of the Collagen Types Essential for Mammalian Breast Acinar Structures., Chandler R Keller, Kelsey F Ruud, Steve R Martinez, and Weimin Li

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Practice trends for perioperative intravesical chemotherapy in upper tract urothelial carcinoma: Low but increasing utilization during minimally invasive nephroureterectomy., Alexander P Kenigsberg, Gianpaolo Carpinito, Samuel A Gold, Xiaosong Meng, Alireza Ghoreifi, Hooman Djaladat, Andrea Minervini, Marcus Jamil, Firas Abdollah, Jason M Farrow, Chandru Sundaram, Robert Uzzo, Matteo Ferro, Margaret Meagher, Ithaar Derweesh, Zhenjie Wu, James R Porter, Andrew Katims, Reza Mehrazin, Alex Mottrie, Giuseppe Simone, Adam C Reese, Daniel D Eun, Amit Satish Bhattu, Mark L Gonzalgo, Umberto Carbonara, Riccardo Autorino, and Vitaly Margulis

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Early Response of Primary Care Practices to COVID-19 Pandemic., Gina Keppel, Allison M Cole, Mary Ramsbottom, Stuti Nagpal, Jaime Hornecker, Claire Thomson, Viet Nguyen, and Laura-Mae Baldwin

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Early Local Therapy for the Primary Site in De Novo Stage IV Breast Cancer: Results of a Randomized Clinical Trial (EA2108)., Seema A Khan, Fengmin Zhao, Lori J Goldstein, David Cella, Mark Basik, Mehra Golshan, Thomas B Julian, Barbara A Pockaj, Christine A Lee, Wajeeha Razaq, Joseph A Sparano, Gildy V Babiera, Irene A Dy, Sarika Jain, Paula Silverman, Carla S Fisher, Amye J Tevaarwerk, Lynne I Wagner, and George W Sledge

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An atypical clinical course of a 71-year-old man with right arm weakness and ataxia., Pravin Khemani, Michael Elliott, and Todd Levine

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KDIGO 2022 Clinical Practice Guideline for Diabetes Management in Chronic Kidney Disease., Kidney Disease: Improving Global Outcomes (KDIGO) Diabetes Work Group and Katherine Tuttle

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Quality of life after long-term biochemical control of acromegaly., Allison Kimball, Laura E Dichtel, Kevin C J Yuen, Whitney W Woodmansee, Melanie S Haines, Lisa B Nachtigall, Brooke Swearingen, Pamela Jones, Nicholas A Tritos, Julie L Sharpless, Ursula B Kaiser, Anu Gerweck, and Karen K Miller

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Clinical Factors and Outcomes When Real-World Heart Teams Overruled STS Risk Scores in TAVR Cases., Jackson M King, Morgan T Black, Ruyun Jin, Gary L Grunkemeier, Branden Reynolds, Brydan Curtis, Robert W. Hodson, Erika A Strehl, Sameer Gafoor, Matthew Forrester, Emily J Cox, and Michael Ring

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Harm Reduction For STHC Patients With Opioid Use Disorder, Michael P. Kinney and Amy G Burns

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Efficacy of secukinumab on dactylitis in patients with active psoriatic arthritis from the FUTURE 5 study., Bruce Kirkham, Peter Nash, Delia Reina, Sandra Navarra, Erhard Quebe-Fehling, Corine Gaillez, Carlos Sastre, and Philip Mease

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Changes in Distensibility Index During an Incremental POEM Myotomy., T B Knowles, Anee Sophia Jackson, Shu-Ching Chang, Drew B Schembre, Alexander S Farivar, Ralph W Aye, and Brian Louie

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The timed 25-foot walk is a more sensitive outcome measure than the EDSS for PPMS trials: an analysis of the PROMISE clinical trial dataset., Marcus W Koch, Jop Mostert, P Repovic, J D Bowen, Jacynthe Comtois, Eva Strijbis, Bernard Uitdehaag, and Gary Cutter

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The nine hole peg test as an outcome measure in progressive MS trials., Marcus W Koch, P Repovic, Jop Mostert, J D Bowen, Jacynthe Comtois, Eva Strijbis, Bernard Uitdehaag, and Gary Cutter

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Outcomes of endoscopic retrograde cholangiography and percutaneous transhepatic biliary drainage in liver transplant recipients with a Roux-en-Y biliary-enteric anastomosis., Divyanshoo Rai Kohli, Bashar A Aqel, Nicole L Segaran, M Edwyn Harrison, Norio Fukami, Douglas O Faigel, Adyr Moss, Amit Mathur, Winston Hewitt, Nitin Katariya, and Rahul Pannala

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Comparative Accuracy of Endosonographic shear wave elastography and Transcutaneous Liver Stiffness Measurement: A pilot study., Divyanshoo R Kohli, Daniel Mettman, Nevene Andraws, Erin Haer, Jaime Porter, Ozlem Ulusurac, Steven Ullery, Madhav Desai, Mohammad S Siddiqui, and Prateek Sharma

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Direct Percutaneous Endoscopic Gastrostomy Versus Radiological Gastrostomy in Patients Unable to Undergo Transoral Endoscopic Pull Gastrostomy., Divyanshoo R Kohli, Craig Smith, Omer Chaudhry, Madhav Desai, Dion DePaolis, and Prateek Sharma

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Interleukin-6 and Cardiovascular and Kidney Outcomes in Patients With Type 2 Diabetes: New Insights From CANVAS., Akihiko Koshino, Meir Schechter, Taha Sen, Priya Vart, Brendon L Neuen, Bruce Neal, Clare Arnott, Vlado Perkovic, Paul M Ridker, Katherine R Tuttle, Michael K Hansen, and Hiddo J L Heerspink

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Emergency Medicine in India - First Step towards Capacity Building., Arva Koushik, Aiman Perween Afsar, Tarun Kumar Suvvari, Lokesh Edara, Arunachalam Einstein, and Ashima Sharma

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Stress Injuries of the Knee., Emily Kraus, Katherine Rizzone, Mahala Walker, Naomi Brown, Japsimran Kaur, Danielle Magrini, Jayden Glover, and Eric Nussbaum

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Factors impacting genomic testing rates among epithelial ovarian cancer patients across a large community-based healthcare system, Nicole M. Kretzer, Christopher J. Darus, Nancy Biery, Roshanthi Weerasinghe, Grace Li, Ann Vita, Shwetha Pindikuri, Amy S. Parrish, Charles W Drescher, and Fernanda B. Musa

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Frequency of homologous recombination deficiency in a large community-based cohort of epithelial ovarian cancer cases, Nicole M. Kretzer, Fernanda B. Musa, Christopher Darus, Nancy Biery, Roshanthi Weerasinghe, Grace Li, Ann Vita, Shwetha Pindikuri, Amy S. Parrish, and Charles W Drescher

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Patterns of genomic testing for epithelial ovarian cancer across a large community-based health care network- a real world experience, Nicole M. Kretzer, Fernanda B. Musa, Christopher Darus, Nancy Biery, Roshanthi Weerasinghe, Grace Li, Ann Vita, Shwetha Pindikuri, Amy S. Parrish, and Charles W Drescher

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Racial and Ethnic Disparities in Acute Care Utilization Among Patients With Glomerular Disease., Jill R Krissberg, Michelle M O'Shaughnessy, Abigail R Smith, Margaret E Helmuth, Salem Almaani, Diego H Aviles, Kaye E Brathwaite, Yi Cai, Daniel Cattran, Rasheed Gbadegesin, Dorey A Glenn, Larry A Greenbaum, Sandra Iragorri, Koyal Jain, Myda Khalid, Jason Kidd, Jeffrey Kopp, Richard Lafayette, Jerome C Lane, Francesca Lugani, Jordan G Nestor, Rulan S Parekh, Kimberly Reidy, David T Selewski, Christine B Sethna, C John Sperati, Katherine Tuttle, Katherine Twombley, Tetyana L Vasylyeva, Donald J Weaver, Scott E Wenderfer, Keisha Gibson, and CureGN Consortium

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Sustained postoperative plasma elevations of plasminogen activator inhibitor-1 following minimally invasive colorectal cancer resection., H M C Shantha Kumara, Poppy Addison, Dasuni N Gamage, Erica Pettke, Abhinit Shah, Xiaohong Yan, Vesna Cekic, and Richard L Whelan

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Using machine learning to predict internal rotation after anatomic and reverse total shoulder arthroplasty., Vikas Kumar, Bradley S Schoch, Christine Allen, Steve Overman, Ankur Teredesai, William Aibinder, Moby Parsons, Jonathan Watling, Jia-Wei Kevin Ko, Bruno Gobbato, Thomas Throckmorton, Howard Routman, and Christopher Roche

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Evolution of the AO Spine Sacral and Pelvic Classification System: a systematic review., Barry Ting Sheen Kweh, Jin W Tee, F Cumhur Oner, Klaus J Schnake, Emiliano N Vialle, Frank Kanziora, Shanmuganathan Rajasekaran, Marcel Dvorak, Jens R Chapman, Lorin M Benneker, Gregory Schroeder, and Alexander R Vaccaro

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The role of adjuvant chemotherapy in the management of acute promyelocytic leukemia differentiation syndrome., Dominic LaBella, Samuel Regan, Heiko Konig, Daniel N Egan, Neil Bailey, Raya Mawad, Morgan Gilbert, John M Pagel, and Jeffrey J Pu

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Radiographic Characteristics of Cervical Deformity (CD) Using a Discriminant Analysis: The Value of Extension Radiographs., Renaud Lafage, Sohrab Virk, Jonathan Elysee, Peter Passias, Christopher Ames, Robert A Hart, Christopher Shaffrey, Gregory Mundis, Themistocles Protopsaltis, Munish Gupta, Eric Klineberg, Douglas Burton, Frank Schwab, Virginie Lafage, and ISSG

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Eligibility for COPD Clinical Trials of Inhaled Triple Therapy: Analysis of the Subpopulations and Intermediate Outcomes in COPD Study (SPIROMICS), Allison A Lambert and See full list of authors in comments

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The AO spine upper cervical injury classification system: Do work setting or trauma center affiliation affect classification accuracy or reliability?, Mark J Lambrechts, Gregory D Schroeder, Brian A Karamian, Jose A Canseco, Richard Bransford, Cumhur Oner, Lorin M Benneker, Frank Kandziora, Rajasekaran Shanmuganathan, Rishi Kanna, Andrei F Joaquim, Jens R Chapman, Emiliano Vialle, Mohammad El-Sharkawi, Marcel Dvorak, Klaus Schnake, Christopher K Kepler, and Alexander R Vaccaro

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Global Validation of the AO Spine Upper Cervical Injury Classification: Geographic Region Affects Reliability and Reproducibility., Mark J Lambrechts, Gregory D Schroeder, Brian A Karamian, Jose A Canseco, Richard Bransford, Cumhur Oner, Lorin M Benneker, Frank Kandziora, Rajasekaran Shanmuganathan, Rishi Kanna, Andrei F Joaquim, Jens R Chapman, Emiliano Vialle, Mohammad El-Sharkawi, Marcel Dvorak, Klaus Schnake, Christopher K Kepler, Alexander R Vaccaro, and AO Spine Upper Cervical Injury Classification International Members

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Safety and efficacy of HSP90 inhibitor ganetespib for neoadjuvant treatment of stage II/III breast cancer., Julie E Lang, Andres Forero-Torres, Douglas Yee, Christina Yau, Denise Wolf, John Park, Barbara A Parker, A Jo Chien, Anne M Wallace, Rashmi Murthy, Kathy S Albain, Erin D Ellis, Heather Beckwith, Barbara B Haley, Anthony D Elias, Judy C Boughey, Rachel L Yung, Claudine Isaacs, Amy S Clark, Hyo S Han, Rita Nanda, Qamar J Khan, Kristen K Edmiston, Erica Stringer-Reasor, Elissa Price, Bonnie Joe, Minetta C Liu, Lamorna Brown-Swigart, Emanuel F Petricoin, Julia D Wulfkuhle, Meredith Buxton, Julia L Clennell, Ashish Sanil, Scott Berry, Smita M Asare, Amy Wilson, Gillian L Hirst, Ruby Singhrao, Adam L Asare, Jeffrey B Matthews, Michelle Melisko, Jane Perlmutter, Hope S Rugo, W Fraser Symmans, Laura J van 't Veer, Nola M Hylton, Angela M DeMichele, Donald A Berry, and Laura J Esserman

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Epidemiology of interstitial lung disease in patients with metastatic breast cancer at baseline and after treatment with HER2-directed therapy: a real-world data analysis., Jeanna Wallenta Law, Alicyn Campbell, Colin Weller, Colden Johanson, Ronda Broome, Elisabeth Piault, Monika Izano, Andrew Schrag, Mary Tran, Thomas D Brown, and Henry G Kaplan

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Real-World Treatment Patterns and Clinical Effectiveness of Palbociclib Plus an Aromatase Inhibitor as First-Line Therapy in Advanced/Metastatic Breast Cancer: Analysis from the US Syapse Learning Health Network., Jeanna Wallenta Law, Debanjali Mitra, Henry G Kaplan, Tamuno Alfred, Adam M Brufsky, Birol Emir, Haley McCracken, Xianchen Liu, Ronda G Broome, Chenan Zhang, Caroline DiCristo, and Connie Chen

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More autopsy studies are needed to understand the pathogenesis of severe COVID-19., Scott P Layne, Kathie-Anne Walters, John C Kash, and Jeffery K Taubenberger

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Proteomics Standards Initiative's ProForma 2.0: Unifying the Encoding of Proteoforms and Peptidoforms., Richard D LeDuc, Eric W Deutsch, Pierre-Alain Binz, Ryan T Fellers, Anthony J Cesnik, Joshua A Klein, Tim Van Den Bossche, Ralf Gabriels, Arshika Yalavarthi, Yasset Perez-Riverol, Jeremy Carver, Wout Bittremieux, Shin Kawano, Benjamin Pullman, Nuno Bandeira, Neil L Kelleher, Paul M Thomas, and Juan Antonio Vizcaíno

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Diabetic Retinopathy and Dementia Association, Beyond Diabetes Severity., Cecilia S Lee, Chloe Krakauer, Yu-Ru Su, Rod Walker, Marian Blazes, Susan M McCurry, J D Bowen, Wayne C McCormick, Aaron Y Lee, Edward Boyko, Ann O'Hare, Eric B Larson, and Paul K Crane

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Cediranib in combination with olaparib in patients without a germline BRCA1/2 mutation and with recurrent platinum-resistant ovarian cancer: Phase IIb CONCERTO trial., Jung-Min Lee, Richard G Moore, Sharad Ghamande, Min Park, John P Diaz, Julia Chapman, James Kendrick, Brian M Slomovitz, Krishnansu S Tewari, Elizabeth S Lowe, Tsveta Milenkova, Sanjeev Kumar, Mike Dymond, Jessica Brown, and Joyce F Liu

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Recent Advances in RNA Therapy and Its Carriers to Treat the Single-Gene Neurological Disorders., Ming-Jen Lee, Inyoul Lee, and Kai Wang

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Daptomycin-Resistant Enterococcus Bacteremia Is Associated With Prior Daptomycin Use and Increased Mortality After Liver Transplantation, Rachael A Lee, Jason D Goldman, Ghady Haidar, Jessica Lewis, Sana Arif, Jonathan Hand, Ricardo M La Hoz, Stephanie Pouch, Eric Holaday, Heather Clauss, Keith S Kaye, and Anoma Nellore

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P2Y1 agonist HIC in combination with androgen receptor inhibitor abiraterone acetate impairs cell growth of prostate cancer., Hien Thi Thu Le, Akshaya Murugesan, Nuno R Candeias, Thiyagarajan Ramesh, Olli Yli-Harja, and Meenakshisundaram Kandhavelu

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Decompression only versus fusion in octogenarians with spinal epidural abscesses: early complications, clinical and radiological outcome with 2-year follow-up., Pavlina Lenga, Gelo Gülec, Awais Akbar Bajwa, Mohammed Issa, Rod J Oskouian, Jens R Chapman, Karl Kiening, Andreas W Unterberg, and Basem Ishak

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Radiological Features in Type II Odontoid Fractures in Older Adults After High- and Low-Energy Trauma., Pavlina Lenga, Mohammed Issa, Lennart Krull, Karl Kiening, Andreas W Unterberg, Till Schneider, Rod J Oskouian, Jens R Chapman, and Basem Ishak

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Healthcare consumption among subjects with otitis media undergoing middle ear surgery-analysis of cost drivers., Aaran T Lewis, Douglas D Backous, Byung Yoon Choi, Rafael Jaramillo, Kelvin Kong, Thomas Lenarz, Jaydip Ray, Alok Thakar, Krister Järbrink, and Myrthe K S Hol

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Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial., Linda M Liau, Keyoumars Ashkan, Steven Brem, Jian L Campian, John E Trusheim, Fabio M Iwamoto, David D Tran, George Ansstas, Charles S Cobbs, Jason A Heth, Michael E Salacz, Stacy D'Andre, Robert D Aiken, Yaron A Moshel, Joo Y Nam, Clement P Pillainayagam, Stephanie A Wagner, Kevin A Walter, Rekha Chaudary, Samuel A Goldlust, Ian Y Lee, Daniela A Bota, Heinrich Elinzano, Jai Grewal, Kevin Lillehei, Tom Mikkelsen, Tobias Walbert, Steven Abram, Andrew J Brenner, Matthew G Ewend, Simon Khagi, Darren S Lovick, Jana Portnow, Lyndon Kim, William G Loudon, Nina L Martinez, Reid C Thompson, David E Avigan, Karen L Fink, Francois J Geoffroy, Pierre Giglio, Oleg Gligich, Dietmar Krex, Scott M Lindhorst, Jose Lutzky, Hans-Jörg Meisel, Minou Nadji-Ohl, Lhagva Sanchin, Andrew Sloan, Lynne P Taylor, Julian K Wu, Erin M Dunbar, Arnold B Etame, Santosh Kesari, David Mathieu, David E Piccioni, David S Baskin, Michel Lacroix, Sven-Axel May, Pamela Z New, Timothy J Pluard, Steven A Toms, Victor Tse, Scott Peak, John L Villano, James D Battiste, Paul J Mulholland, Michael L Pearlman, Kevin Petrecca, Michael Schulder, Robert M Prins, Alton L Boynton, and Marnix L Bosch

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Successful endovascular treatment of abdominal aortic rupture secondary to bacillus Calmette-Guérin vaccine., Andrew E Liechty, Albert Pacifico, and Peter Brant-Zawadzki

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A Multimodal Pain Management Strategy for Burn Patients., Kara L Liechty, Kelly Shields, Emily Ogden, Niknam Eshraghi, Michelle Dedeo, and Pamela Bishop

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The Impact of Preoperative Breast Characteristics on Immediate Breast Reconstruction Complications: A Multivariate analysis of Tissue Expander and Autologous Reconstruction, Jeffrey N. Li, Sumeer S. Teotia, and Nicholas T. Haddock