Providence research from Washington locations.

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Submissions from 2020

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Toward Increased Reliability, Transparency, and Accessibility in Cross-linking Mass Spectrometry., Alexander Leitner, Alexandre M J J Bonvin, Christoph H Borchers, Robert J Chalkley, Julia Chamot-Rooke, Colin W Combe, Jürgen Cox, Meng-Qiu Dong, Lutz Fischer, Michael Götze, Fabio C Gozzo, Albert J R Heck, Michael R Hoopmann, Lan Huang, Yasushi Ishihama, Andrew R Jones, Nir Kalisman, Oliver Kohlbacher, Karl Mechtler, Robert L Moritz, Eugen Netz, Petr Novak, Evgeniy Petrotchenko, Andrej Sali, Richard A Scheltema, Carla Schmidt, David Schriemer, Andrea Sinz, Frank Sobott, Florian Stengel, Konstantinos Thalassinos, Henning Urlaub, Rosa Viner, Juan A Vizcaíno, Marc R Wilkins, and Juri Rappsilber

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Longitudinal analysis reveals transition barriers between dominant ecological states in the gut microbiome., Roie Levy, Andrew T Magis, John C Earls, Ohad Manor, Tomasz Wilmanski, Jennifer Lovejoy, Sean M Gibbons, Gilbert S Omenn, Leroy Hood, and Nathan D Price

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Proceedings of the 2019 Santa Fe Bone Symposium: New Concepts in the Care of Osteoporosis and Rare Bone Diseases., E Michael Lewiecki, John P Bilezikian, Risa Kagan, Deborah Krakow, Michael R McClung, Paul D Miller, Eric T Rush, Christopher R Shuhart, Nelson B Watts, and Elaine W Yu

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MEMOTE for standardized genome-scale metabolic model testing., Christian Lieven, Moritz E Beber, Brett G Olivier, Frank T Bergmann, Meric Ataman, Parizad Babaei, Jennifer A Bartell, Lars M Blank, Siddharth Chauhan, Kevin Correia, Christian Diener, Andreas Dräger, Birgitta E Ebert, Janaka N Edirisinghe, José P Faria, Adam M Feist, Georgios Fengos, Ronan M T Fleming, Beatriz García-Jiménez, Vassily Hatzimanikatis, Wout van Helvoirt, Christopher S Henry, Henning Hermjakob, Markus J Herrgård, Ali Kaafarani, Hyun Uk Kim, Zachary King, Steffen Klamt, Edda Klipp, Jasper J Koehorst, Matthias König, Meiyappan Lakshmanan, Dong-Yup Lee, Sang Yup Lee, Sunjae Lee, Nathan E Lewis, Filipe Liu, Hongwu Ma, Daniel Machado, Radhakrishnan Mahadevan, Paulo Maia, Adil Mardinoglu, Gregory L Medlock, Jonathan M Monk, Jens Nielsen, Lars Keld Nielsen, Juan Nogales, Intawat Nookaew, Bernhard O Palsson, Jason A Papin, Kiran R Patil, Mark Poolman, Nathan D Price, Osbaldo Resendis-Antonio, Anne Richelle, Isabel Rocha, Benjamín J Sánchez, Peter J Schaap, Rahuman S Malik Sheriff, Saeed Shoaie, Nikolaus Sonnenschein, Bas Teusink, Paulo Vilaça, Jon Olav Vik, Judith A H Wodke, Joana C Xavier, Qianqian Yuan, Maksim Zakhartsev, and Cheng Zhang

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Publisher Correction: MEMOTE for standardized genome-scale metabolic model testing., Christian Lieven, Moritz E Beber, Brett G Olivier, Frank T Bergmann, Meric Ataman, Parizad Babaei, Jennifer A Bartell, Lars M Blank, Siddharth Chauhan, Kevin Correia, Christian Diener, Andreas Dräger, Birgitta E Ebert, Janaka N Edirisinghe, José P Faria, Adam M Feist, Georgios Fengos, Ronan M T Fleming, Beatriz García-Jiménez, Vassily Hatzimanikatis, Wout van Helvoirt, Christopher S Henry, Henning Hermjakob, Markus J Herrgård, Ali Kaafarani, Hyun Uk Kim, Zachary King, Steffen Klamt, Edda Klipp, Jasper J Koehorst, Matthias König, Meiyappan Lakshmanan, Dong-Yup Lee, Sang Yup Lee, Sunjae Lee, Nathan E Lewis, Filipe Liu, Hongwu Ma, Daniel Machado, Radhakrishnan Mahadevan, Paulo Maia, Adil Mardinoglu, Gregory L Medlock, Jonathan M Monk, Jens Nielsen, Lars Keld Nielsen, Juan Nogales, Intawat Nookaew, Bernhard O Palsson, Jason A Papin, Kiran R Patil, Mark Poolman, Nathan D Price, Osbaldo Resendis-Antonio, Anne Richelle, Isabel Rocha, Benjamín J Sánchez, Peter J Schaap, Rahuman S Malik Sheriff, Saeed Shoaie, Nikolaus Sonnenschein, Bas Teusink, Paulo Vilaça, Jon Olav Vik, Judith A H Wodke, Joana C Xavier, Qianqian Yuan, Maksim Zakhartsev, and Cheng Zhang

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iREAD: a tool for intron retention detection from RNA-seq data., Hong-Dong Li, Cory C Funk, and Nathan D Price

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IsoResolve: Predicting Splice Isoform Functions by Integrating Gene and Isoform-level Features with Domain Adaptation., Hong-Dong Li, Changhuo Yang, Zhimin Zhang, Mengyun Yang, Fang-Xiang Wu, Gilbert S Omenn, and Jianxin Wang

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The power of social media: A call for change in professional perspective., Kira Long

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Selective Translation of Low Abundance and Upregulated Transcripts in Halobacterium salinarum., Adrián López García de Lomana, Ulrike Kusebauch, Arjun V Raman, Min Pan, Serdar Turkarslan, Alan P R Lorenzetti, Robert L Moritz, and Nitin Baliga

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Commentary: Defining low-risk lesions for esophageal preservation informed by resecting the organ., Brian Louie

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Commentary: Toward Minimally Invasive Management of Epiphrenic Diverticula., Brian Louie

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Response to the Comment on "Objective Evidence of Reflux Control After Magnetic Sphincter Augmentation: One Year Results From a Post Approval Study"., Brian Louie, Christy Dunst, and John C Lipham

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A synthesis of bacterial and archaeal phenotypic trait data., Joshua S Madin, Daniel A Nielsen, Maria Brbic, Ross Corkrey, David Danko, Kyle Edwards, Martin K M Engqvist, Noah Fierer, Jemma L Geoghegan, Michael Gillings, Nikos C Kyrpides, Elena Litchman, Christopher E Mason, Lisa Moore, Søren L Nielsen, Ian T Paulsen, Nathan D Price, T B K Reddy, Matthew A Richards, Eduardo P C Rocha, Thomas M Schmidt, Heba Shaaban, Maulik Shukla, Fran Supek, Sasha G Tetu, Sara Vieira-Silva, Alice R Wattam, David A Westfall, and Mark Westoby

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Untargeted longitudinal analysis of a wellness cohort identifies markers of metastatic cancer years prior to diagnosis., Andrew T Magis, Noa Rappaport, Matthew P Conomos, Gilbert S Omenn, Jennifer C Lovejoy, Leroy Hood, and Nathan D Price

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Graph-based exploitation of gene ontology using GOxploreR for scrutinizing biological significance., Kalifa Manjang, Shailesh Tripathi, Olli Yli-Harja, Matthias Dehmer, and Frank Emmert-Streib

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Health and disease markers correlate with gut microbiome composition across thousands of people., Ohad Manor, Chengzhen L Dai, Sergey A Kornilov, Brett Smith, Nathan D Price, Jennifer C Lovejoy, Sean M Gibbons, and Andrew T Magis

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Consensus-Building efforts to identify best tools for screening and assessment for supportive services in oncology., Timothy F Marshall, Catherine M Alfano, Alix G Sleight, Richard P Moser, David S Zucker, Elise L Rice, Julie K Silver, Vishwa S Raj, Jack B Fu, Lynne S Padgett, Kathleen Doyle Lyons, Mary Vining Radomski, Raymond McKenna, and Mackenzi Pergolotti

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Roles of bacteriophages, plasmids and CRISPR immunity in microbial community dynamics revealed using time-series integrated meta-omics., Susana Martínez Arbas, Shaman Narayanasamy, Malte Herold, Laura A Lebrun, Michael R Hoopmann, Sujun Li, Tony J Lam, Benoît J Kunath, Nathan D Hicks, Cindy M Liu, Lance B Price, Cedric C Laczny, John D Gillece, James M Schupp, Paul S Keim, Robert L Moritz, Karoline Faust, Haixu Tang, Yuzhen Ye, Alexander Skupin, Patrick May, Emilie E L Muller, and Paul Wilmes

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A Structural Model of the Endogenous Human BAF Complex Informs Disease Mechanisms., Nazar Mashtalir, Hiroshi Suzuki, Daniel P Farrell, Akshay Sankar, Jie Luo, Martin Filipovski, Andrew R D'Avino, Roodolph St Pierre, Alfredo M Valencia, Takashi Onikubo, Robert G Roeder, Yan Han, Yuan He, Jeffrey A Ranish, Frank DiMaio, Thomas Walz, and Cigall Kadoch

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Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality., Fred D Mast, Arti T Navare, Almer M van der Sloot, Jasmin Coulombe-Huntington, Michael P Rout, Nitin Baliga, Alexis Kaushansky, Brian T Chait, Alan Aderem, Charles M Rice, Andrej Sali, Mike Tyers, and John D Aitchison

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Presentation 1209-083: Soluble FMS-Like Tyrosine Kinase-1 (Sflt-1) is Associated with Subclinical and Clinical ASCVD: The Dallas Heart Study, Rina Mauricio, Kavisha Singh, Monika Sanghavi, Colby Ayers, Anand Rohatgi, Wanpen Vongpatanasin, James de Lemos, and Amit Khera

Ineffective esophageal motility is not a contraindication to total fundoplication in appropriately selected patients The Annual Meeting of The Society of American Gastrointestinal and Endoscopic Surgeons Cleveland, Ohio, BM McCall, CL Wilshire, and See all authors in comments

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Author Correction: New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections., Martin McPhillie, Ying Zhou, Kamal El Bissati, Jitender Dubey, Hernan Lorenzi, Michael Capper, Amanda K Lukens, Mark Hickman, Stephen Muench, Shiv Kumar Verma, Christopher R Weber, Kelsey Wheeler, James Gordon, Justin Sanders, Hong Moulton, Kai Wang, Taek-Kyun Kim, Yuqing He, Tatiana Santos, Stuart Woods, Patty Lee, David Donkin, Eric Kim, Laura Fraczek, Joseph Lykins, Farida Esaa, Fatima Alibana-Clouser, Sarah Dovgin, Louis Weiss, Gael Brasseur, Dyann Wirth, Michael Kent, Leroy Hood, Brigitte Meunieur, Craig W Roberts, S Samar Hasnain, Svetlana V Antonyuk, Colin Fishwick, and Rima McLeod

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Chronic elevation of plasma vascular endothelial growth factor-A (VEGF-A) is associated with a history of blast exposure., James S Meabon, David G Cook, Mayumi Yagi, Garth E Terry, Donna J Cross, Mark Muzi, Kathleen F Pagulayan, Aric F Logsdon, Abigail G Schindler, Vikas Ghai, Kai Wang, Shannon Fallen, Yong Zhou, Taek-Kyun Kim, Inyoul Lee, William A Banks, Erik S Carlson, Cynthia Mayer, Rebecca C Hendrickson, Murray A Raskind, Desiree A Marshall, Daniel P Perl, C Dirk Keene, and Elaine R Peskind

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Poor prognostic factors in predicting abatacept response in a phase III randomized controlled trial in psoriatic arthritis., Philip J Mease, Iain B McInnes, Vibeke Strand, Oliver FitzGerald, Harris A Ahmad, Yedid Elbez, and Subhashis Banerjee

Return to work and functional status shows prolonged impact following management of a complicated pleural space infection The American Thoracic Society Philadelphia, Pennsylvania, AM Meggyesy, CL Wilshire, and See all authors in comments

Stage IV non-small cell lung cancer outpatient palliative care referral results in longer survival but no decrease in hospital resource utilization in the last 30 days of life The American Thoracic Society Philadelphia, Pennsy, AM Meggyesy, CL Wilshire, and See all authors in comments

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DIALib-QC an assessment tool for spectral libraries in data-independent acquisition proteomics., Mukul K Midha, David S Campbell, Charu Kapil, Ulrike Kusebauch, Michael R Hoopmann, Samuel L Bader, and Robert L Moritz

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A comprehensive spectral assay library to quantify the Escherichia coli proteome by DIA/SWATH-MS., Mukul K Midha, Ulrike Kusebauch, David Shteynberg, Charu Kapil, Samuel L Bader, Panga Jaipal Reddy, David S Campbell, Nitin Baliga, and Robert L Moritz

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A Review of the Scientific Rigor, Reproducibility, and Transparency Studies Conducted by the ABRF Research Groups., Sheenah M Mische, Nancy C Fisher, Susan M Meyn, Katia Sol Church, Rebecca L Hegstad-Davies, Frances Weis-Garcia, Marie Adams, John M Ashton, Kym M Delventhal, Julie A Dragon, Laura Holmes, Pratik Jagtap, Christopher E Mason, Magnus Palmblad, Brian C Searle, Christoph W Turck, and Kevin L Knudtson

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Comment on: "Active Surveillance Versus Immediate Surgery in Clinically Complete Responders After Neoadjuvant Chemoradiotherapy for Esophageal Cancer"., Daniela Molena, Brian Louie, and Steven R Demeester

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Simplified care-pathway selection for nonspecialist practice: the GLOBAL Primary Biliary Cholangitis Study Group Age, Bilirubin, Alkaline phosphatase risk assessment tool., Carla F Murillo Perez, Aliya Gulamhusein, Marco Carbone, Palak J Trivedi, Adriaan J van der Meer, Christophe Corpechot, Pier Maria Battezzati, Willem J Lammers, Nora Cazzagon, Annarosa Floreani, Albert Parés, Frederik Nevens, Ana Lleo, Marlyn J Mayo, Kris V Kowdley, Cyriel Y Ponsioen, George N Dalekos, Nikolaos K Gatselis, Douglas Thorburn, Andrew L Mason, Harry Janssen, Xavier Verhelst, Tony Bruns, Keith D Lindor, Olivier Chazouillères, Pietro Invernizzi, Bettina E Hansen, Gideon M Hirschfield, and GLOBAL PBC Study Group

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Design and synthesis of novel quinic acid derivatives:, Akshaya Murugesan, Suvi Holmstedt, Kenna C Brown, Alisa Koivuporras, Ana S Macedo, Nga Nguyen, Pedro Fonte, Patrícia Rijo, Olli Yli-Harja, Nuno R Candeias, and Meenakshisundaram Kandhavelu

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Transcriptomic analysis of glioblastoma multiforme providing new insights into GPR17 signaling communication., Gnanavel Mutharasu, Akshaya Murugesan, Saravanan Konda Mani, Olli Yli-Harja, and Meenakshisundaram Kandhavelu

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Effect of Pembrolizumab Plus Neoadjuvant Chemotherapy on Pathologic Complete Response in Women With Early-Stage Breast Cancer: An Analysis of the Ongoing Phase 2 Adaptively Randomized I-SPY2 Trial., Rita Nanda, Minetta C Liu, Christina Yau, Rebecca Shatsky, Lajos Pusztai, Anne Wallace, A Jo Chien, Andres Forero-Torres, Erin D Ellis, Heather Han, Amy Clark, Kathy Albain, Judy C Boughey, Nora T Jaskowiak, Anthony Elias, Claudine Isaacs, Kathleen Kemmer, Teresa Helsten, Melanie Majure, Erica Stringer-Reasor, Catherine Parker, Marie C Lee, Tufia Haddad, Ronald N Cohen, Smita Asare, Amy Wilson, Gillian L Hirst, Ruby Singhrao, Katherine Steeg, Adam Asare, Jeffrey B Matthews, Scott Berry, Ashish Sanil, Richard Schwab, W Fraser Symmans, Laura van 't Veer, Douglas Yee, Angela DeMichele, Nola M Hylton, Michelle Melisko, Jane Perlmutter, Hope S Rugo, Donald A Berry, and Laura J Esserman

POSTER: Optimizing Transgender Identification in Epic at the STHC Family Medicine Clinic., Cedar Neary, Sarah Wilhelm, and Amy Burns

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Efficacy of tofacitinib in reducing pain in patients with rheumatoid arthritis, psoriatic arthritis or ankylosing spondylitis., Alexis Ogdie, Kurt de Vlam, Iain B McInnes, Philip J Mease, Philip Baer, Tatjana Lukic, David Gruben, Kenneth Kwok, Cunshan Wang, Ming-Ann Hsu, and Anna Maniccia

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Pilot Study of an Integrated Smartphone and Breathalyzer Contingency Management Intervention for Alcohol Use., Oladunni Oluwoye, Hailey Reneau, Jalene Herron, Karl C Alcover, Sterling M McPherson, John Roll, and Michael G McDonell

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Research on the Human Proteome Reaches a Major Milestone: >90% of Predicted Human Proteins Now Credibly Detected, According to the HUPO Human Proteome Project., Gilbert S Omenn, Lydie Lane, Christopher M Overall, Ileana M Cristea, Fernando J Corrales, Cecilia Lindskog, Young-Ki Paik, Jennifer E Van Eyk, Siqi Liu, Stephen R Pennington, Michael P Snyder, Mark S Baker, Nuno Bandeira, Ruedi Aebersold, Robert L Moritz, and Eric W Deutsch

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Effect of Secukinumab on the Different GRAPPA-OMERACT Core Domains in Psoriatic Arthritis: A Pooled Analysis of 2049 Patients., Ana-Maria Orbai, Iain B McInnes, Laura C Coates, M Elaine Husni, Dafna D Gladman, Laure Gossec, Luminita Pricop, Olivier Chambenoit, Xiangyi Meng, and Philip Mease

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Treatment selection in patients with relapsed or refractory follicular lymphoma., John M Pagel

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Refining the management of relapsed or refractory follicular lymphoma., John M Pagel, John M Burke, and Lori A Leslie

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Refining the management of relapsed or refractory follicular lymphoma: case scenarios., John M Pagel, John M Burke, and Lori A Leslie

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Antiproliferative and apoptotic effects of indole derivative, N-(2-hydroxy-5-nitrophenyl (4'-methylphenyl) methyl) indoline in breast cancer cells., Suresh Palanivel, Akshaya Murugesan, Kumar Subramanian, Olli Yli-Harja, and Meenakshisundaram Kandhavelu

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Inflammation resolution: a dual-pronged approach to averting cytokine storms in COVID-19?, Dipak Panigrahy, Molly M Gilligan, Sui Huang, Allison Gartung, Irene Cortés-Puch, Patricia J Sime, Richard P Phipps, Charles N Serhan, and Bruce D Hammock

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Deep phenotyping during pregnancy for predictive and preventive medicine., Alison G Paquette, Leroy Hood, Nathan D Price, and Yoel Sadovsky

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Prevalence of Gastrointestinal Symptoms and Fecal Viral Shedding in Patients With Coronavirus Disease 2019: A Systematic Review and Meta-analysis., Sravanthi Parasa, Madhav Desai, Viveksandeep Thoguluva Chandrasekar, Harsh K Patel, Kevin F Kennedy, Thomas Roesch, Marco Spadaccini, Matteo Colombo, Roberto Gabbiadini, Everson L A Artifon, Alessandro Repici, and Prateek Sharma

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Global Impact of the COVID-19 Pandemic on Endoscopy: An International Survey of 252 Centers from 55 Countries., Sravanthi Parasa, Nageshwar Reddy, Douglas O Faigel, Alessandro Repici, Fabian Emura, and Prateek Sharma

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Pre-existing immunity to influenza virus hemagglutinin stalk might drive selection for antibody-escape mutant viruses in a human challenge model., Jae-Keun Park, Yongli Xiao, Mitchell D Ramuta, Luz Angela Rosas, Sharon Fong, Alexis M Matthews, Ashley D Freeman, Monica A Gouzoulis, Natalia A Batchenkova, Xingdong Yang, Kelsey Scherler, Li Qi, Susan Reed, Rani Athota, Lindsay Czajkowski, Alison Han, David M Morens, Kathie-Anne Walters, Matthew J Memoli, John C Kash, and Jeffery K Taubenberger

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Investigating the Effects of Brainstem Neuronal Adaptation on Cardiovascular Homeostasis., James H Park, Jonathan Gorky, Babatunde Ogunnaike, Rajanikanth Vadigepalli, and James S Schwaber

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A Phase 2, Open-Label, Multicenter Study of Tazemetostat in Combination with Rituximab for the Treatment of Relapsed or Refractory Follicular Lymphoma, Krish Patel, Neil Bailey, and John M Pagel

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Real World Observational Study Using Clonoseq® Next Generation Sequencing in Hematologic Malignancies: The 'Watch' Registry, Krish Patel, Neil Bailey, John M Pagel, and See all authors in comments

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Employed Mothers’ Satisfaction with the Breastfeeding Provisions in the Patient Protection and Affordable Care Act, Rebecca Penders

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Intricate Genetic Programs Controlling Dormancy in Mycobacterium tuberculosis., Eliza Jr Peterson, Abrar A Abidi, Mario L Arrieta-Ortiz, Boris Aguilar, James T Yurkovich, Amardeep Kaur, Min Pan, Vivek Srinivas, Ilya Shmulevich, and Nitin Baliga

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Causal mutations from adaptive laboratory evolution are outlined by multiple scales of genome annotations and condition-specificity., Patrick V Phaneuf, James T Yurkovich, David Heckmann, Muyao Wu, Troy E Sandberg, Zachary A King, Justin Tan, Bernhard O Palsson, and Adam M Feist

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Ageotypes: Distinct Biomolecular Trajectories in Human Aging., Brian D. Piening, Jennifer Lovejoy, and John C Earls

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Acquiring and Analyzing Data Independent Acquisition Proteomics Experiments without Spectrum Libraries., Lindsay K Pino, Seth C Just, Michael J MacCoss, and Brian C Searle

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Absence of full-length dystrophin impairs normal maturation and contraction of cardiomyocytes derived from human-induced pluripotent stem cells., J Manuel Pioner, Xuan Guan, Jordan M Klaiman, Alice W Racca, Lil Pabon, Veronica Muskheli, Jesse Macadangdang, Cecilia Ferrantini, Michael R Hoopmann, Robert L Moritz, Deok-Ho Kim, Chiara Tesi, Corrado Poggesi, Charles E Murry, Martin K Childers, David L Mack, and Michael Regnier

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Decision Matrix-Guided Treatment of Infected Hip Resurfacing., James W. Pritchett

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AKI and Hypercalcemia in a Patient with Weakness and Fatigue., Cheyenne Rahimi, Mathias Stroemel, and Nicole K Andeen

POSTER: Improving Metabolic Monitoring Guideline Adherence in Psychiatry Residency Outpatient Clinic., Shane Rall, Amy Burns, and Lucas Salg

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Birds of a Feather? Genetic Counseling, Genetic Testing, and Humanism., Robert Resta

Comparison of echocardiographic outcomes following transcatheter aortic valve replacement with Edwards S3 23mm versus Medtronic Evolut 26mm valves, Michael Ring, Ruyun Jin, Rollie Parrish, Brydan Curtis, Matthew Forrester, Branden Reynolds, and Sameer Gafoor

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Gemogenovatucel-T (Vigil) immunotherapy as maintenance in frontline stage III/IV ovarian cancer (VITAL): a randomised, double-blind, placebo-controlled, phase 2b trial., Rodney P Rocconi, Elizabeth A Grosen, Sharad A Ghamande, John K Chan, Minal A Barve, Jonathan Oh, Devansu Tewari, Peter C Morris, Erin E Stevens, Justin N Bottsford-Miller, Min Tang, Phylicia Aaron, Laura Stanbery, Staci Horvath, Gladice Wallraven, Ernest Bognar, Luisa Manning, John Nemunaitis, David Shanahan, Brian M Slomovitz, Thomas J Herzog, Bradley J Monk, and Robert L Coleman

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P0516 (S1638). - An Unexpected Cause of Colitis in a Cardiac Transplant Patient, Medora D. Rodrigues, Michele Rooney, Deirdre M Mooney, Nishant Puri, and Steve Serrao

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P0357 (S1601). - Malignant Melanoma of the Gallbladder Masquerading as Cholangitis and Cholecystitis, Medora Rodrigues, Sanjay Logani, Juan Mejia, Wichit Srikureja, and Nishant Puri

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Retrospective multicenter study on endoscopic treatment of upper gastrointestinal postsurgical leaks., Eduardo Rodrigues-Pinto, Pedro Pereira, Bernardo Sousa-Pinto, Hany Shehab, Rolando Pinho, Michael C Larsen, Shayan Irani, Richard A Kozarek, Antonio Capogreco, Alessandro Repici, Ealaf Shemmeri, Brian Louie, Pawel Rogalski, Andrzej Baniukiewicz, Andrzej Dabrowski, João Correia de Sousa, Silvia Barrias, Yervant Ichkhanian, Vivek Kumbhari, Mouen A Khashab, Nicole Bowers, Allison R Schulman, and Guilherme Macedo

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Worldwide Examination of Patients with CLL Hospitalized for COVID-19, Lindsey E. Roeker, Neil Bailey, and See full list of authors in comments

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Emergence of Organisms., Andrea Roli and Stuart A Kauffman

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A small sustained increase in NOD1 abundance promotes ligand-independent inflammatory and oncogene transcriptional responses., Leah M Rommereim, Ajay Suresh Akhade, Bhaskar Dutta, Carolyn Hutcheon, Nicolas W Lounsbury, Clifford C Rostomily, Ram Savan, Iain D C Fraser, Ronald N Germain, and Naeha Subramanian

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Composition of Caenorhabditis elegans extracellular vesicles suggests roles in metabolism, immunity, and aging., Joshua C Russell, Taek-Kyun Kim, Ayush Noori, Gennifer E Merrihew, Julia E Robbins, Alexandra Golubeva, Kai Wang, Michael J MacCoss, and Matt Kaeberlein

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Modeling the Hepatology Workforce in the United States: A Predicted Critical Shortage., Mark W Russo, Oren K Fix, Ayman A Koteish, Katie Duggan, Marcia Ditmyer, Michael Fuchs, Raymond T Chung, and Gautham Reddy

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Society for Immunotherapy of Cancer clinical and biomarkers data sharing resource document: Volume I-conceptual challenges., Sergio Rutella, Michael A Cannarile, Sacha Gnjatic, Bruno Gomes, Justin Guinney, Vaios Karanikas, Mohan Karkada, John M Kirkwood, Beatrix Kotlan, Giuseppe V Masucci, Els Meeusen, Anne Monette, Aung Naing, Vésteinn Thorsson, Nicholas Tschernia, Ena Wang, Daniel K Wells, Timothy L Wyant, and Alessandra Cesano

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Advancing human health in the decade ahead: pregnancy as a key window for discovery: A Burroughs Wellcome Fund Pregnancy Think Tank., Yoel Sadovsky, Sam Mesiano, Graham J Burton, Michelle Lampl, Jeffrey C Murray, Rachel M Freathy, Anita Mahadevan-Jansen, Ashley Moffett, Nathan D Price, Paul H Wise, Derek E Wildman, Ralph Snyderman, Nigel Paneth, John Anthony Capra, Marcelo A Nobrega, Yaacov Barak, and Louis J Muglia

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Defining the proteolytic landscape during enterovirus infection., Mohsan Saeed, Sebastian Kapell, Nicholas T Hertz, Xianfang Wu, Kierstin Bell, Alison W Ashbrook, Milica Tesic Mark, Henry A Zebroski, Maxwell L Neal, Malin Flodström-Tullberg, Margaret R MacDonald, John D Aitchison, Henrik Molina, and Charles M Rice

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Semiautomated Glasgow-Blatchford Bleeding Score helps direct bed placement for patients with upper gastrointestinal bleeding., Drew B Schembre, Robson E Ely, Janice M Connolly, Kunjali T Padhya, Rohit Sharda, and John J Brandabur

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Generating high quality libraries for DIA MS with empirically corrected peptide predictions., Brian C Searle, Kristian E Swearingen, Christopher A Barnes, Tobias Schmidt, Siegfried Gessulat, Bernhard Küster, and Mathias Wilhelm

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The Influence of Surgical Intervention and Sagittal Alignment on Frailty in Adult Cervical Deformity., Frank A Segreto, Peter Gust Passias, Avery E Brown, Samantha R Horn, Cole A Bortz, Katherine E Pierce, Haddy Alas, Virginie Lafage, Renaud Lafage, Justin S Smith, Breton G Line, Bassel G Diebo, Michael P Kelly, Gregory M Mundis, Themistocles S Protopsaltis, Alex Soroceanu, Han Jo Kim, Eric O Klineberg, Douglas C Burton, Robert A Hart, Frank J Schwab, Shay Bess, Christopher I Shaffrey, and Christopher P Ames

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Serum-borne lipids amplify TLR-activated inflammatory responses., Naveen Sharma, Ajay Suresh Akhade, Sana Ismaeel, and Ayub Qadri

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Developing Quality Metrics For Upper Endoscopy., Prateek Sharma, Sravanthi Parasa, and Nicholas Shaheen

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Use of a report card to evaluate outcomes of achalasia surgery: beyond the Eckardt score., Ealaf Shemmeri, Ralph W Aye, Alexander S Farivar, Adam J Bograd, and Brian E Louie

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Circulating MicroRNAs and Extracellular Vesicle-Containing MicroRNAs as Response Biomarkers of Anti-programmed Cell Death Protein 1 or Programmed Death-Ligand 1 Therapy in NSCLC., Takehito Shukuya, Vikas Ghai, Joseph M Amann, Tamio Okimoto, Konstantin Shilo, Taek-Kyun Kim, Kai Wang, and David P Carbone

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Current Status and Future Prospects of Genome-Scale Metabolic Modeling to Optimize the Use of Mesenchymal Stem Cells in Regenerative Medicine., Þóra Sigmarsdóttir, Sarah McGarrity, Óttar Rolfsson, James T Yurkovich, and Ólafur E Sigurjónsson

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Discovery of a new ligament of the lumbar spine: the midline interlaminar ligament., Emily Simonds, Joe Iwanaga, Basem Ishak, Miguel Angel Reina, Rod J Oskouian, and R Shane Tubbs

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Using Simulation to Assess Cardiology Fellow Performance of Transthoracic Echocardiography: Lessons for Training in the COVID-19 Pandemic., Kavisha Singh, Alvin Chandra, Katy Lonergan, and Anish Bhatt

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Associations Between High-Density Lipoprotein Particles and Ischemic Events by Vascular Domain, Sex, and Ethnicity: A Pooled Cohort Analysis., Kavisha Singh, Alvin Chandra, Thomas Sperry, Parag H Joshi, Amit Khera, Salim S Virani, Christie M Ballantyne, James D Otvos, Robin P F Dullaart, Eke G Gruppen, Margery A Connelly, Colby R Ayers, and Anand Rohatgi

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Presentation 1375-288: When a Pulmonary Embolism is more than meets the eye: Initial Presentation of Patent Ductus Arteriosus in an Adult, Kavisha Singh, Amit Khera, and Michael Luna

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Abstract 14090: Multiparity is Associated With Aortic Pathology in Women From the Dallas Heart Study, Kavisha Singh, Rina Mauricio, Wanpen Vongpatanasin, Katy Lonergan, Monika Sanghavi, Amit Khera, James A De Lemos, Colby Ayers, and Parag H. Joshi

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Behavior-related gene regulatory networks: A new level of organization in the brain., Saurabh Sinha, Beryl M Jones, Ian M Traniello, Syed A Bukhari, Marc S Halfon, Hans A Hofmann, Sui Huang, Paul S Katz, Jason Keagy, Vincent J Lynch, Marla B Sokolowski, Lisa J Stubbs, Shayan Tabe-Bordbar, Mariana F Wolfner, and Gene E Robinson

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The Cancer Rehabilitation Medicine Metrics Consortium: A Path to Enhanced, Multi-Site Outcome Assessment to Enhance Care and Demonstrate Value., Sean R Smith, Mary Vargo, David S Zucker, Maryanne Henderson, Samman Shahpar, Eric M Wisotzky, Christian Custodio, Jeffrey Basford, Gina Jay, Lynn Gerber, and Andrea Cheville

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Surgical Management of Non-Small Cell Lung Cancer Invading the Fissure: Less Is More?, Shane P Smith, Adam J Bograd, Gal Levy, Shu-Ching Chang, Alexander S Farivar, Ralph W Aye, Brian Louie, and Eric Vallieres

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PerSort Facilitates Characterization and Elimination of Persister Subpopulation in Mycobacteria., Vivek Srinivas, Mario L Arrieta-Ortiz, Amardeep Kaur, Eliza Jr Peterson, and Nitin Baliga

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Dynamics of a birth-death process based on combinatorial innovation., Mike Steel, Wim Hordijk, and Stuart A Kauffman

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Multiomic Immunophenotyping of COVID-19 Patients Reveals Early Infection Trajectories., Yapeng Su, Daniel Chen, Christopher Lausted, Dan Yuan, Jongchan Choi, Cheng Dai, Valentin Voillet, Kelsey Scherler, Pamela Troisch, Venkata R Duvvuri, Priyanka Baloni, Guangrong Qin, Brett Smith, Sergey Kornilov, Clifford Rostomily, Alex Xu, Jing Li, Shen Dong, Alissa Rothchild, Jing Zhou, Kim Murray, Rick Edmark, Sunga Hong, Lesley Jones, Yong Zhou, Ryan Roper, Sean Mackay, D Shane O'Mahony, Christopher Dale, Julie A Wallick, Heather A Algren, Zager A Michael, Andrew T Magis, Wei Wei, Nathan D Price, Sui Huang, Naeha Subramanian, Kai Wang, Jennifer Hadlock, Leroy Hood, Alan Aderem, Jeffrey A Bluestone, Lewis L Lanier, Phil Greenberg, Raphael Gottardo, Mark M Davis, Jason D Goldman, James R Heath, and ISB-Swedish COVID19 Biobanking Unit

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Multi-omics resolves a sharp disease-state shift between mild and moderate COVID-19, Yapeng Su, Daniel Chen, Dan Yuan, Christopher Lausted, Jongchan Choi, Chengzhen L Dai, Valentin Voillet, Venkata R Duvvuri, Kelsey Scherler, Pamela Troisch, Priyanka Baloni, Guangrong Qin, Brett Smith, Sergey A Kornilov, Clifford Rostomily, Alex Xu, Jing Li, Shen Dong, Alissa Rothchild, Jing Zhou, Kim Murray, Rick Edmark, Sunga Hong, John Heath, John Earls, Rongyu Zhang, Jingyi Xie, Sarah Li, Ryan Roper, Lesley Jones, Yong Zhou, Lee Rowen, Rachel Liu, Sean Mackay, D Shane O'Mahony, chris dale, Julie A Wallick, Heather A Algren, Zager A. Michael, ISB-Swedish COVID19 Biobanking Unit, Wei Wei, Nathan D Price, Sui Huang, Naeha Subramanian, Kai Wang, Andrew T Magis, Jennifer Hadlock, Leroy Hood, Alan Aderem, Jeffrey A. Bluestone, Lewis L. Lanier, Philip D. Greenberg, Raphael Gottardo, Mark M. Davis, Jason D Goldman, and James R. Heath

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Multi-omic single-cell snapshots reveal multiple independent trajectories to drug tolerance in a melanoma cell line., Yapeng Su, Melissa E Ko, Hanjun Cheng, Ronghui Zhu, Min Xue, Jessica Wang, Jihoon W Lee, Luke Frankiw, Alexander Xu, Stephanie Wong, Lidia Robert, Kaitlyn Takata, Dan Yuan, Yue Lu, Sui Huang, Antoni Ribas, Raphael Levine, Garry P Nolan, Wei Wei, Sylvia K Plevritis, Guideng Li, David Baltimore, and James R Heath

POSTER: CLOSE ALL THE CRACKS! TRANSITIONS OF CARE IN THE OUTPATIENT SETTING, Brian Swett, Christine Prato, and Amy Burns

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Active learning narrows achievement gaps for underrepresented students in undergraduate science, technology, engineering, and math., Elli J Theobald, Mariah J Hill, Elisa Tran, Sweta Agrawal, E Nicole Arroyo, Shawn Behling, Nyasha Chambwe, Dianne Laboy Cintrón, Jacob D Cooper, Gideon Dunster, Jared A Grummer, Kelly Hennessey, Jennifer Hsiao, Nicole Iranon, Leonard Jones, Hannah Jordt, Marlowe Keller, Melissa E Lacey, Caitlin E Littlefield, Alexander Lowe, Shannon Newman, Vera Okolo, Savannah Olroyd, Brandon R Peecook, Sarah B Pickett, David L Slager, Itzue W Caviedes-Solis, Kathryn E Stanchak, Vasudha Sundaravardan, Camila Valdebenito, Claire R Williams, Kaitlin Zinsli, and Scott Freeman

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Multiplatform Integrative Analysis of Immunogenomic Data for Biomarker Discovery., Vésteinn Thorsson

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Sequential Wnt Agonist Then Antagonist Treatment Accelerates Tissue Repair and Minimizes Fibrosis., Xiao-Jun Tian, Dong Zhou, Haiyan Fu, Rong Zhang, Xiaojie Wang, Sui Huang, Youhua Liu, and Jianhua Xing