Providence research from Washington locations.

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Submissions from 2020

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Visualizing metabolic network dynamics through time-series metabolomic data., Lea F Buchweitz, James T Yurkovich, Christoph Blessing, Veronika Kohler, Fabian Schwarzkopf, Zachary A King, Laurence Yang, Freyr Jóhannsson, Ólafur E Sigurjónsson, Óttar Rolfsson, Julian Heinrich, and Andreas Dräger

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Rib Plating Offers Favorable Outcomes in Patients With Chronic Nonunion of Prior Rib Fractures., Kerrie E Buehler, Candice Wilshire, Adam J Bograd, and Eric Vallieres

Imaging center administrators report a lack of physician champion and resources for follow-up as barriers to lung cancer screening implementation in a community-based healthcare network The American Thoracic Society Philadelphia, Pennsylvania, KE Buehler, CL Wilshire, and See all authors in comments

In the last month of life the majority of patients with stage IV non-small cell lung cancer experience in-hospital days and in-hospital death The American Thoracic Society Philadelphia, Pennsylvania, KE Buehler, CL Wilshire, and See all authors in comments

OPIOID USE DISORDERS IN THE HOSPITALIZED PATIENT: CHRONIC DISEASE OR MORAL FAILING, Amy Burns

POSTER: Reducing Treatment inequity of Substance use Disorders through Education., Amy Burns and See full list of authors in the comments

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Impact of pulmonary function on pulmonary complications after robotic-assisted thoracoscopic lobectomy., Christopher Cao, Brian E Louie, Franca Melfi, Giulia Veronesi, Rene Razzak, Gaetano Romano, Pierluigi Novellis, Neel K Ranganath, and Bernard J Park

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Discovery of driver non-coding splice-site-creating mutations in cancer., Song Cao, Daniel Cui Zhou, Clara Oh, Reyka G Jayasinghe, Yanyan Zhao, Christopher J Yoon, Matthew A Wyczalkowski, Matthew H Bailey, Terrence Tsou, Qingsong Gao, Andrew Malone, Sheila Reynolds, Ilya Shmulevich, Michael C Wendl, Feng Chen, and Li Ding

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Community standards to facilitate development and address challenges in metabolic modeling., Maureen A Carey, Andreas Dräger, Moritz E Beber, Jason A Papin, and James T Yurkovich

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Selective carbon sources influence the end products of microbial nitrate respiration., Hans K Carlson, Lauren M Lui, Morgan N Price, Alexey E Kazakov, Alex V Carr, Jennifer V Kuehl, Trenton K Owens, Torben Nielsen, Adam P Arkin, and Adam M Deutschbauer

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Comprehensive Analysis of Genetic Ancestry and Its Molecular Correlates in Cancer., Jian Carrot-Zhang, Nyasha Chambwe, Jeffrey S Damrauer, Theo A Knijnenburg, A Gordon Robertson, Christina Yau, Wanding Zhou, Ashton C Berger, Kuan-Lin Huang, Justin Y Newberg, R Jay Mashl, Alessandro Romanel, Rosalyn W Sayaman, Francesca Demichelis, Ina Felau, Garrett M Frampton, Seunghun Han, Katherine A Hoadley, Anab Kemal, Peter W Laird, Alexander J Lazar, Xiuning Le, Ninad Oak, Hui Shen, Christopher K Wong, Jean C Zenklusen, Elad Ziv, Cancer Genome Atlas Analysis Network, Andrew D Cherniack, and Rameen Beroukhim

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Systematic comparison of sea urchin and sea star developmental gene regulatory networks explains how novelty is incorporated in early development., Gregory A Cary, Brenna S McCauley, Olga Zueva, Joseph Pattinato, William J R Longabaugh, and Veronica F Hinman

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STARS interventions for violence reduction: Safety, technology, activity, relief, and surroundings., Christina Anne Case

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STARS Interventions for Continuous Observation and Violence Reduction: Safety, Technology, Activity, Relief, Surroundings., Christina Anne Case

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Minimally Invasive Esophagectomy: A Consensus Statement., Robert J Cerfolio, Anne-Sophie Laliberte, Shanda Blackmon, Jelle P Ruurda, Richard van Hillegersberg, Inderpal Sarkaria, and Brian Louie

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Society for Immunotherapy of Cancer clinical and biomarkers data sharing resource document: Volume II-practical challenges., Alessandra Cesano, Michael A Cannarile, Sacha Gnjatic, Bruno Gomes, Justin Guinney, Vaios Karanikas, Mohan Karkada, John M Kirkwood, Beatrix Kotlan, Giuseppe V Masucci, Els Meeusen, Anne Monette, Aung Naing, Vésteinn Thorsson, Nicholas Tschernia, Ena Wang, Daniel K Wells, Timothy L Wyant, and Sergio Rutella

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Cancer Systems Biology in the Era of Single-Cell Multi-Omics., Hanjun Cheng, Rong Fan, and Wei Wei

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A novel landscape of nuclear human CDK2 substrates revealed by in situ phosphorylation., Yong Chi, John H Carter, Jherek Swanger, Alexander V Mazin, Robert L Moritz, and Bruce E Clurman

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Unique challenges for glioblastoma immunotherapy - Discussions across neuro-oncology and non-neuro-oncology experts in cancer immunology., Pavlina Chuntova, Frances Chow, Payal Watchmaker, Mildred Galvez, Amy B Heimberger, Evan W Newell, Aaron Diaz, Ronald A DePinho, Ming O Li, E John Wherry, Duane Mitchell, Masaki Terabe, Derek A Wainwright, Jay A Berzofsky, Christel Herold-Mende, James R Heath, Michael Lim, Kim A Margolin, E Antonio Chiocca, Noriyuki Kasahara, Benjamin M Ellingson, Christine Brown, Yvonne Chen, Peter Fecci, David A Reardon, Gavin P Dunn, Linda M Liau, Joseph F Costello, Wolfgang Wick, Timothy Cloughesy, William C Timmer, Patrick Y Wen, Robert M Prins, Michael Platten, and Hideho Okada

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Clinician engagement in research as a path toward the learning health system: A regional survey across the northwestern United States., Elizabeth L Ciemins, Brenda L Mollis, Jeannine M Brant, Laurie A Hassell, Sandra Albritton, Paul Amoroso, Angela Lloyd, Jodi M Smith, Bethann M Pflugeisen, Katherine R Tuttle, and Laura-Mae Baldwin

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Inferring evolutionary pathways and directed genotype networks of foodborne pathogens., Oliver M Cliff, Natalia McLean, Vitali Sintchenko, Kristopher M Fair, Tania C Sorrell, Stuart Kauffman, and Mikhail Prokopenko

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Subgroup analysis of clinical and MRI outcomes in participants with a first clinical demyelinating event at risk of multiple sclerosis in the ORACLE-MS study., Bruce A C Cree, James D Bowen, Hans-Peter Hartung, Patrick Vermersch, Bruce Hughes, Doris Damian, Yann Hyvert, Fernando Dangond, Andrew Galazka, Megan Grosso, Daniel L Jones, and Thomas P Leist

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Synthesizing Systems Biology Knowledge from Omics Using Genome-Scale Models., Sanjeev Dahal, James T Yurkovich, Hao Xu, Bernhard O Palsson, and Laurence Yang

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Characterizing diversity in the tumor-immune microenvironment of distinct subclasses of gastroesophageal adenocarcinomas., S Derks, L K de Klerk, X Xu, T Fleitas, K X Liu, Y Liu, F Dietlein, C Margolis, A M Chiaravalli, A C Da Silva, S Ogino, F G Akarca, G J Freeman, S J Rodig, J L Hornick, E van Allen, B Li, S X Liu, V Thorsson, and A J Bass

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The ProteomeXchange consortium in 2020: enabling 'big data' approaches in proteomics., Eric W Deutsch, Nuno Bandeira, Vagisha Sharma, Yasset Perez-Riverol, Jeremy J Carver, Deepti J Kundu, David García-Seisdedos, Andrew F Jarnuczak, Suresh Hewapathirana, Benjamin S Pullman, Julie Wertz, Zhi Sun, Shin Kawano, Shujiro Okuda, Yu Watanabe, Henning Hermjakob, Brendan MacLean, Michael J MacCoss, Yunping Zhu, Yasushi Ishihama, and Juan A Vizcaíno

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MICOM: Metagenome-Scale Modeling To Infer Metabolic Interactions in the Gut Microbiota., Christian Diener, Sean M Gibbons, and Osbaldo Resendis-Antonio

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Progressive Shifts in the Gut Microbiome Reflect Prediabetes and Diabetes Development in a Treatment-Naive Mexican Cohort., Christian Diener, María de Lourdes Reyes-Escogido, Lilia M Jimenez-Ceja, Mariana Matus, Claudia M Gomez-Navarro, Nathaniel D Chu, Vivian Zhong, M Elizabeth Tejero, Eric Alm, Osbaldo Resendis-Antonio, and Rodolfo Guardado-Mendoza

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Outcomes following early versus delayed cholecystectomy performed for acute cholangitis., Andrew Discolo, Shelby Reiter, Bryce French, Danielle Hayes, Gary Lucas, Lancy Tan, James Scanlan, and Ryan Martinez

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Glioblastoma Multiforme Stem Cell Cycle Arrest by Alkylaminophenol Through the Modulation of EGFR and CSC Signaling Pathways., Phuong Doan, Aliyu Musa, Akshaya Murugesan, Vili Sipilä, Nuno R Candeias, Frank Emmert-Streib, Pekka Ruusuvuori, Kirsi Granberg, Olli Yli-Harja, and Meenakshisundaram Kandhavelu

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Scrotal and Penile Erythrodysesthesia Associated with Neoadjuvant Capecitabine Chemoradiation., Julie Dricken, Erica Pettke, John A Griffin, Henry Y Li, and Vivek Mehta

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Raman-guided subcellular pharmaco-metabolomics for metastatic melanoma cells., Jiajun Du, Yapeng Su, Chenxi Qian, Dan Yuan, Kun Miao, Dongkwan Lee, Alphonsus H C Ng, Reto S Wijker, Antoni Ribas, Raphael D Levine, James R Heath, and Lu Wei

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Connections Between Amyloid Beta and the Meningeal Lymphatics As a Possible Route for Clearance and Therapeutics., Graham Dupont, Joe Iwanaga, Emre Yilmaz, and R Shane Tubbs

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CRI iAtlas: an interactive portal for immuno-oncology research., James A Eddy, Vésteinn Thorsson, Andrew E Lamb, David L Gibbs, Carolina Heimann, Jia Xin Yu, Verena Chung, Yooree Chae, Kristen Dang, Benjamin G Vincent, Ilya Shmulevich, and Justin Guinney

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Artificial Intelligence: A Clarification of Misconceptions, Myths and Desired Status., Frank Emmert-Streib, Olli Yli-Harja, and Matthias Dehmer

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Extending Comet for Global Amino Acid Variant and Post-Translational Modification Analysis using the PSI Extended FASTA Format (PEFF)., Jimmy K Eng and Eric W Deutsch

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Longitudinal Effects of Left Ventricular Assist Device Implantation on Global and Domain-Specific Cognitive Function., Kenneth M Faulkner, Christopher V Chien, Quin E Denfeld, Jill M Gelow, Karen S Lyons, Kathleen L Grady, James O Mudd, and Christopher S Lee

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The Efficacy of Passive Valve Antimicrobial Swab Caps Against Existing Clabsi Prevention Bundle in an Adult Hematology Inpatient Population: A Quality Improvement Initiative, Joseph F. Ferry, Neil Bailey, Vanessa Dunleavy, Joanna Fesler, Judson Hall, Sonia Glennie, William Bensinger, Raya Mawad, Krish Patel, Daniel N Egan, John M Pagel, and Livia Hegerova

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Resolution of eicosanoid/cytokine storm prevents carcinogen and inflammation-initiated hepatocellular cancer progression., Anna Fishbein, Weicang Wang, Haixia Yang, Jun Yang, Victoria M Hallisey, Jianjun Deng, Sanne M L Verheul, Sung Hee Hwang, Allison Gartung, Yuxin Wang, Diane R Bielenberg, Sui Huang, Mark W Kieran, Bruce D Hammock, and Dipak Panigrahy

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It's Time to Rethink Our Assumptions About Acute Wilson's Disease., Oren K Fix

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Clinical Best Practice Advice for Hepatology and Liver Transplant Providers During the COVID-19 Pandemic: AASLD Expert Panel Consensus Statement., Oren K Fix, Bilal Hameed, Robert J Fontana, Ryan M Kwok, Brendan M McGuire, David C Mulligan, Daniel S Pratt, Mark W Russo, Michael L Schilsky, Elizabeth C Verna, Rohit Loomba, David E Cohen, Jorge A Bezerra, K Rajender Reddy, and Raymond T Chung

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Telemedicine and Telehepatology During the COVID-19 Pandemic., Oren K Fix and Marina Serper

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Safety and efficacy of magnetic sphincter augmentation dilation., Reid Fletcher, Christy M Dunst, Walaa F Abdelmoaty, Evan T Alicuben, Ealaf Shemmeri, Brett Parker, Dolores Müller, Ahmed M Sharata, Kevin M Reavis, Daniel Davila Bradley, Nikolai A Bildzukewicz, Brian Louie, John C Lipham, and Steven R DeMeester

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Transcriptional portrait of M. bovis BCG during biofilm production shows genes differentially expressed during intercellular aggregation and substrate attachment., Mario Alberto Flores-Valdez, Michel de Jesús Aceves-Sánchez, Eliza Jr Peterson, Nitin Baliga, Jorge Bravo-Madrigal, Miguel Ángel De la Cruz-Villegas, Miguel A Ares, Sarah Born, Martin Voskuil, Nayeli Areli Pérez-Padilla, Mirna Burciaga-Flores, Tanya Amanda Camacho-Villegas, and María Guadalupe Espinoza-Jorge

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RepeatModeler2 for automated genomic discovery of transposable element families., Jullien M Flynn, Robert Hubley, Clément Goubert, Jeb Rosen, Andrew G Clark, Cédric Feschotte, and Arian F Smit

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Colon and Rectal Surgery Robotic Training Programs: An Evaluation of Gender Disparities., Katherine E Foley, Kevin M Izquierdo, Madrigal G von Muchow, Amir Bastawrous, Robert K Cleary, and Mark K Soliman

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Conversion From Knee Arthrodesis Back to Arthroplasty: A Particular Challenge in Combination With Fungal Periprosthetic Joint Infection., Sven Frieler, Emre Yilmaz, Ryan Goodmanson, Yannik Hanusrichter, Thomas A Schildhauer, and Hinnerk Baecker

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Atlas of Transcription Factor Binding Sites from ENCODE DNase Hypersensitivity Data across 27 Tissue Types., Cory C Funk, Alex M Casella, Segun Jung, Matthew A Richards, Alex Rodriguez, Paul Shannon, Rory Donovan-Maiye, Ben Heavner, Kyle Chard, Yukai Xiao, Gustavo Glusman, Nilufer Ertekin-Taner, Todd E Golde, Arthur Toga, Leroy Hood, John D Van Horn, Carl Kesselman, Ian Foster, Ravi Madduri, Nathan D Price, and Seth A Ament

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Alterations in plasma microRNA and protein levels in war veterans with chronic mild traumatic brain injury., Vikas Ghai, Shannon Fallen, David Baxter, Kelsey Scherler, Taek-Kyun Kim, Yong Zhou, James Meabon, Aric Logsdon, William Allen Banks, Abigail Schindler, David Cook, Elaine Peskind, Inyoul Lee, and Kai Wang

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Keystone taxa indispensable for microbiome recovery., Sean M Gibbons

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Publisher Correction: Keystone taxa indispensable for microbiome recovery., Sean M Gibbons

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Life Is Really Simple, but We Insist on Making It Complicated-Lessons From Confucius on Ultrasound Use in the ICU., Christopher R Gilbert, Fabien Maldonado, Lonny B Yarmus, Jason A Akulian, Candice Wilshire, and Jed A Gorden

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Life Is Really Simple, but We Insist on Making It Complicated-Lessons From Confucius on Ultrasound Use in the ICU., Christopher R Gilbert, Fabien Maldonado, Lonny B Yarmus, Jason A Akulian, Candice Wilshire, and Jed A Gorden

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Poor Monitor Screen Height Positioning by Pulmonologists During Flexible Bronchoscopy: A Nested, Prospective Observational Trial., Christopher R Gilbert, Jeffrey Thiboutot, Alexander Chen, A Christine Argento, Nicholas J Pastis, Hans J Lee, Andrew D Lerner, and Lonny B Yarmus

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Assessment of Ergonomic Strain and Positioning During Bronchoscopic Procedures: A Feasibility Study., Christopher R Gilbert, Jeffrey Thiboutot, Christopher Mallow, Alexander Chen, Nicholas J Pastis, A Christine Argento, Jennifer Millar, Robert A Lavin, Andrew D Lerner, Diana H Yu, Ben Salwen, Daniel Lunz, Hans J Lee, and Lonny B Yarmus

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Management of Indwelling Tunneled Pleural Catheters: A Modified Delphi Consensus Statement., Christopher R Gilbert, Momen M Wahidi, Richard W Light, M Patricia Rivera, Daniel H Sterman, Rajesh Thomas, Samira Shojaee, Shmuel Shoham, Ionnis Psallidas, David E Ost, Daniela Molena, Nick Maskell, Fabien Maldonado, Moishe Liberman, Y C Gary Lee, Hans Lee, Felix J F Herth, Horiana Grosu, Jed A Gorden, Edward T H Fysh, John P Corcoran, A Christine Argento, Jason A Akulian, Najib M Rahman, and Lonny B Yarmus

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Key Highlights for the College of American Pathology Statement on Collection and Handling of Thoracic Small Biopsy and Cytology Specimens for Ancillary Studies., Christopher R Gilbert, Momen M Wahidi, Lonny B Yarmus, Sinchita Roy-Chowdhuri, and Nicholas J Pastis

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Retained Granulation Cuff as a Complication of Indwelling Pleural Catheter Removal., Christopher R Gilbert, Candice Wilshire, and Jed A Gorden

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Absolute quantification of transcription factors in human erythropoiesis using selected reaction monitoring mass spectrometry., Mark A Gillespie, Carmen G Palii, Daniel Sanchez-Taltavull, Theodore J Perkins, Marjorie Brand, and Jeffrey A Ranish

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Absolute Quantification of Transcription Factors Reveals Principles of Gene Regulation in Erythropoiesis., Mark A Gillespie, Carmen G Palii, Daniel Sanchez-Taltavull, Paul Shannon, William J R Longabaugh, Damien J Downes, Karthi Sivaraman, Herbert M Espinoza, Jim R Hughes, Nathan D Price, Theodore J Perkins, Jeffrey A Ranish, and Marjorie Brand

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Primary Sclerosing Cholangitis: Epidemiology, Genetics, Diagnosis, and Current Management., Eric Gochanour, Channa Jayasekera, and Kris V Kowdley

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Utilization of Claims Data in Research: Are We Missing the Forest and the Trees?, Jed A Gorden, Candice Wilshire, and Christopher R Gilbert

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Prospective Study of Use of Edmonton Symptom Assessment Scale Versus Routine Symptom Management During Weekly Radiation Treatment Visits., Uma D Goyal, Kristen Riegert, Rajayogesh Davuluri, Shawn Ong, Sun K Yi, Shona T Dougherty, and Charles C Hsu

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Community is the Best Medicine, Ryder Gwinn, James Bowen, and Nancy B. Isenberg

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Number needed to treat with ursodeoxycholic acid therapy to prevent liver transplantation or death in primary biliary cholangitis., Maren H Harms, Rozanne C de Veer, Willem J Lammers, Christophe Corpechot, Douglas Thorburn, Harry L A Janssen, Keith D Lindor, Palak J Trivedi, Gideon M Hirschfield, Albert Pares, Annarosa Floreani, Marlyn J Mayo, Pietro Invernizzi, Pier Maria Battezzati, Frederik Nevens, Cyriel Y Ponsioen, Andrew L Mason, Kris V Kowdley, Bettina E Hansen, Henk R van Buuren, and Adriaan J van der Meer

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Endoscopic transpapillary stenting for the management of acute cholecystitis., Danielle Hayes, Gary Lucas, Andrew Discolo, Bryce French, and Sean Wells

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Is interval appendectomy really needed? A closer look at neoplasm rates in adult patients undergoing interval appendectomy after complicated appendicitis., Danielle Hayes, Shelby Reiter, Ed Hagen, Gary Lucas, Isabelle Chu, Tobias Muñiz, and Ryan Martinez

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Interdisciplinary Profile: An Established Chemist Journeys into Different Disciplines., James R Heath

POSTER: Patient-Focused Clinical Pathway for Inpatient Management of Opioid Use Disorder (OUD), Chris Hellekson, Amy Burns, and See full list of authors in comments

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Integration of time-series meta-omics data reveals how microbial ecosystems respond to disturbance., Malte Herold, Susana Martínez Arbas, Shaman Narayanasamy, Abdul R Sheik, Luise A K Kleine-Borgmann, Laura A Lebrun, Benoît J Kunath, Hugo Roume, Irina Bessarab, Rohan B H Williams, John D Gillece, James M Schupp, Paul S Keim, Christian Jäger, Michael R Hoopmann, Robert L Moritz, Yuzhen Ye, Sujun Li, Haixu Tang, Anna Heintz-Buschart, Patrick May, Emilie E L Muller, Cedric C Laczny, and Paul Wilmes

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Lumenal calcification and microvasculopathy in fetuin-A-deficient mice lead to multiple organ morbidity., Marietta Herrmann, Anne Babler, Irina Moshkova, Felix Gremse, Fabian Kiessling, Ulrike Kusebauch, Valentin Nelea, Rafael Kramann, Robert L Moritz, Marc D McKee, and Willi Jahnen-Dechent

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Improving Exempt Nurse Leader Work-Life Balance: An Innovation Study, Shelly Hicks Cain

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Facebook Live: Dr. Rod Hochman, Providence CEO and Prof. Jim Health Ph.D. discuss the science around Coronavirus., Rod Hochman and Jim Heath

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Engaging an unstably housed population with low-barrier buprenorphine treatment at a syringe services program: Lessons learned from Seattle, Washington., Julia E Hood, Caleb J Banta-Green, Jeffrey S Duchin, Joseph Breuner, Wendy Dell, Brad Finegood, Sara N Glick, Malin Hamblin, Shayla Holcomb, Darla Mosse, Thea Oliphant-Wells, and Mi-Hyun Mia Shim

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Insights from the First Phosphopeptide Challenge of the MS Resource Pillar of the HUPO Human Proteome Project., Michael R Hoopmann, Ulrike Kusebauch, Magnus Palmblad, Nuno Bandeira, David Shteynberg, Lingjie He, Bin Xia, Stoyan H Stoychev, Gilbert S Omenn, Susan T Weintraub, and Robert L Moritz

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Quality and Clinical Care Development in Spine Surgery-Connecting the Dots: An Expanded Clinical Narrative., Sarah Hopkins, Polly Brune, Jens R Chapman, Marc Horton, Rod J Oskouian, Akshal Patel, and Marc D Moisi

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Average Fitness Differences on NK Landscapes., Wim Hordijk, Stuart A Kauffman, and Peter F Stadler

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Building a circular RNA centered gene regulation network associated with cervical squamous cell carcinoma., Wei Hu, Qingqing Li, Xiaoyi He, Ming Gao, Zhanfu Zheng, Yuanlin Ding, Kai Wang, and Yuqing He

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Internal and External Validation of a 90-Day Percentage Erection Fullness Score Model Predicting Potency Recovery Following Robot-assisted Radical Prostatectomy., Linda M Huynh, Douglas Skarecky, Timothy Wilson, Clayon Lau, Christian Wagner, James Porter, Jorn H Witt, and Thomas E Ahlering

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Chapter: Cognitive Neurology, Nancy B. Isenberg

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Tips for Healthy Aging: A Conversation About Dementia with Dr. Nancy Isenberg, Nancy B. Isenberg

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The Petroclinoid Ligament: Its Morphometrics, Relationships, Variations, and Suggestion for New Terminology., Joe Iwanaga, Juan J Altafulla, Santiago Gutierrez, Graham Dupont, Koichi Watanabe, Zachary Litvack, and R Shane Tubbs

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Modulation of Immune Checkpoints by Chemotherapy in Human Colorectal Liver Metastases., Neda Jabbari, Heidi L Kenerson, Christopher Lausted, Xiaowei Yan, Changting Meng, Kevin M Sullivan, Priyanka Baloni, Dani E Bergey, Venu G Pillarisetty, Leroy Hood, Raymond S Yeung, and Qiang Tian

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Staging System for Neuroendocrine Tumors of the Lung Needs to Incorporate Histologic Grade., Anee Sophia Jackson, Adam Rosenthal, Maria Cattoni, Adam J Bograd, Alexander S Farivar, Ralph W Aye, Eric Vallières, and Brian Louie

Primary surgical management of complicated pleural space infections has superior outcomes when compared to intra-pleural fibrinolytic therapy, AS Jackson, CL Wilshire, SC Chang, LC Horslen, JR Rayburn, CC Fuller, AS Farivar, AJ Bograd, RW Aye, BE Louie, E Vallières, CR Gilbert, and JA Gorden

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Comparative lipidomics of 5-Fluorouracil-sensitive and -resistant colorectal cancer cells reveals altered sphingomyelin and ceramide controlled by acid sphingomyelinase (SMPD1)., Jae Hun Jung, Kohei Taniguchi, Hyeong Min Lee, Min Young Lee, Raju Bandu, Kazumasa Komura, Kil Yeon Lee, Yukihiro Akao, and Kwang Pyo Kim

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National Cancer Institute Think-Tank Meeting Report on Proteomic Cartography and Biomarkers at the Single-Cell Level: Interrogation of Premalignant Lesions., Jacob Kagan, Robert L Moritz, Richard Mazurchuk, Je Hyuk Lee, Peter Vasili Kharchenko, Orit Rozenblatt-Rosen, Eytan Ruppin, Fredrik Edfors, Fiona Ginty, Yury Goltsev, James A Wells, John LaCava, Jessica L Riesterer, Ronald N Germain, Tujin Shi, Mark S Chee, Bogdan A Budnik, John R Yates, Brian T Chait, Jeffery R Moffitt, Richard D Smith, and Sudhir Srivastava

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Answering Schrödinger's "What Is Life?", Stuart Kauffman

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Theory of chemical evolution of molecule compositions in the universe, in the Miller-Urey experiment and the mass distribution of interstellar and intergalactic molecules., Stuart A Kauffman, Dávid Péter Jelenfi, and Gábor Vattay

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Theory of chemical evolution of molecule compositions in the universe, in the Miller-Urey experiment and the mass distribution of interstellar and intergalactic molecules., Stuart A Kauffman, Dávid Péter Jelenfi, and Gábor Vattay

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An Exploratory Pilot Study with Plasma Protein Signatures Associated with Response of Patients with Depression to Antidepressant Treatment for 10 Weeks., Eun Young Kim, Hee-Sung Ahn, Min Young Lee, Jiyoung Yu, Jeonghun Yeom, Hwangkyo Jeong, Hophil Min, Hyun Jeong Lee, Kyunggon Kim, and Yong Min Ahn

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Assembly of SNAPc, Bdp1, and TBP on the U6 snRNA gene promoter in Drosophila melanogaster., Mun Kyoung Kim, An Tranvo, Ann Marie Hurlburt, Neha Verma, Phuc Phan, Jie Luo, Jeff Ranish, and William E Stumph

Core transcriptional regulatory circuits in prion diseases., Taek-Kyun Kim, Inyoul Lee, Ji-Hoon Cho, Brenda Canine, Andrew Keller, Nathan D Price, Daehee Hwang, George Carlson, and Leroy Hood

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Cholecystectomy for Biliary Pancreatitis Is Often Not Performed During Index Hospitalization and Is Associated With Worse Outcomes., Divyanshoo R Kohli, Madhav Desai, Kevin F Kennedy, Sravanthi Parasa, and Prateek Sharma

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Plasma levels of soluble ACE2are associated with sex, Metabolic Syndrome, and its biomarkers in a large cohort, pointing to a possible mechanism for increased severity in COVID-19., Sergey A Kornilov, Isabelle Lucas, Kathleen Jade, Chengzhen L Dai, Jennifer C Lovejoy, and Andrew T Magis

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Ineffective esophageal motility is not a contraindication to total fundoplication., Anne-Sophie Laliberte, Brian Louie, Candice Wilshire, Alexander S Farivar, Adam J Bograd, and Ralph W Aye

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Patterns of Alcohol Use After Early Liver Transplantation for Alcoholic Hepatitis., Brian P Lee, Gene Y Im, John P Rice, Ann Lazar, Ethan Weinberg, Hyosun Han, Haripriya Maddur, R Mark Ghobrial, George Therapondos, Christine Hsu, Oren K Fix, Sheila Eswaran, Kirti Shetty, Jag Chhatwal, Ozden O Dalgic, Neha Jakhete, Constance Mobley, David W Victor, Neil Mehta, Lisanne Dinges, Mary Rinella, Thomas D Schiano, Michael R Lucey, and Norah Terrault

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Phase 1 study of CWP232291 in patients with relapsed or refractory acute myeloid leukemia and myelodysplastic syndrome., Je-Hwan Lee, Stefan Faderl, John M Pagel, Chul Won Jung, Sung-Soo Yoon, Animesh D Pardanani, Pamela S Becker, Howard Lee, Jeongeun Choi, Kyoungjune Lee, Minkyoung Kim, and Jorge E Cortes

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Epigenome signatures landscaped by histone H3K9me3 are associated with the synaptic dysfunction in Alzheimer's disease., Min Young Lee, Junghee Lee, Seung Jae Hyeon, Hyesun Cho, Yu Jin Hwang, Jong-Yeon Shin, Ann C McKee, Neil W Kowall, Jong-Il Kim, Thor D Stein, Daehee Hwang, and Hoon Ryu

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Characterizing the cancer-associated microbiome with small RNA sequencing data., Wei-Hao Lee, Kai-Pu Chen, Kai Wang, Hsuan-Cheng Huang, and Hsueh-Fen Juan

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Invited Commentary., Eric J Lehr and John Petersen