Providence research from Washington locations.

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Submissions from 2019

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Cancer cell population growth kinetics at low densities deviate from the exponential growth model and suggest an Allee effect., Kaitlyn E Johnson, Grant Howard, William Mo, Michael K Strasser, Ernesto A B F Lima, Sui Huang, and Amy Brock

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Cancer cell population growth kinetics at low densities deviate from the exponential growth model and suggest an Allee effect., Kaitlyn E Johnson, Grant Howard, William Mo, Michael K Strasser, Ernesto A B F Lima, Sui Huang, and Amy Brock

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Assessing protein sequence database suitability using de novo sequencing., Richard Johnson, Brian C Searle, Brook L Nunn, Jason M Gilmore, Molly Phillips, Chris T Amemiya, Michelle Heck, and Michael J MacCoss

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An Inflammatory Landscape for Preoperative Neurologic Deficits in Glioblastoma., Amal Katrib, Hyun-Hwan Jeong, Nina L Fransen, Kristin S Henzel, and Jeremy A Miller

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Genomic and molecular characterization of preterm birth., Theo A Knijnenburg, Joseph G Vockley, Nyasha Chambwe, David L Gibbs, Crystal Humphries, Kathi C Huddleston, Elisabeth Klein, Prachi Kothiyal, Ryan Tasseff, Varsha Dhankani, Dale L Bodian, Wendy S W Wong, Gustavo Glusman, Denise E Mauldin, Michael Miller, Joseph Slagel, Summer Elasady, Jared C Roach, Roger Kramer, Kalle Leinonen, Jasper Linthorst, Rajiv Baveja, Robin Baker, Benjamin D Solomon, Greg Eley, Ramaswamy K Iyer, George L Maxwell, Brady Bernard, Ilya Shmulevich, Leroy Hood, and John E Niederhuber

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Underestimation of Liver Transplantation for Alcoholic Hepatitis in the National Transplant Database., Brian P Lee, Gene Y Im, John P Rice, Ethan Weinberg, Christine Hsu, Oren K Fix, George Therapondos, Hyosun Han, David W Victor, Sheila Eswaran, Haripriya Maddur, and Norah A Terrault

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Model to Calculate Harms and Benefits of Early vs Delayed Liver Transplantation for Patients with Alcohol-Associated Hepatitis., Brian P Lee, Sumeyye Samur, Ozden O Dalgic, Emily D Bethea, Michael R Lucey, Ethan Weinberg, Christine Hsu, Mary E Rinella, Gene Y Im, Oren K Fix, George Therapondos, Hyosun Han, David W Victor, Michael D Voigt, Sheila Eswaran, Norah A Terrault, and Jagpreet Chhatwal

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The Impact of Moyamoya Disease and, Ming-Jen Lee, Shannon Fallen, Yong Zhou, David Baxter, Kelsey Scherler, Meng-Fai Kuo, and Kai Wang

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Distinct Profiles of Cell-Free MicroRNAs in Plasma of Veterans with Post-Traumatic Stress Disorder., Min Young Lee, David Baxter, Kelsey Scherler, Taek-Kyun Kim, Xiaogang Wu, Duna Abu-Amara, Janine Flory, Rachel Yehuda, Charles Marmar, Marti Jett, Inyoul Lee, Kai Wang, and Leroy Hood

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A biological function based biomarker panel optimization process., Min Young Lee, Taek-Kyun Kim, Kathie-Anne Walters, and Kai Wang

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Characterizing the cancer-associated microbiome with small RNA sequencing data., Wei-Hao Lee, Kai-Pu Chen, Kai Wang, Hsuan-Cheng Huang, and Hsueh-Fen Juan

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Synthesis and preclinical validation of novel P2Y1 receptor ligands as a potent anti-prostate cancer agent., Hien Thi Thu Le, Tatu Rimpilainen, Saravanan Konda Mani, Akshaya Murugesan, Olli Yli-Harja, Nuno R Candeias, and Meenakshisundaram Kandhavelu

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The Impact of Gravity vs Suction-driven Therapeutic Thoracentesis on Pressure-related Complications: The GRAVITAS Multicenter Randomized Controlled Trial., Robert J Lentz, Samira Shojaee, Horiana B Grosu, Otis B Rickman, Lance Roller, Jasleen K Pannu, Zachary S DePew, Labib G Debiane, Joseph C Cicenia, Jason Akulian, Charla Walston, Trinidad M Sanchez, Kevin R Davidson, Nikhil Jagan, Sahar Ahmad, Christopher R Gilbert, John T Huggins, Heidi Chen, Richard W Light, Lonny Yarmus, David Feller-Kopman, Hans Lee, Najib M Rahman, and Fabien Maldonado

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Inhibition of heme sequestration of histidine-rich protein 2 using multiple epitope-targeted peptides., JingXin Liang, David N Bunck, Anvita Mishra, Sunga Hong, Matthew N Idso, and James R Heath

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Inhibition of heme sequestration of histidine-rich protein 2 using multiple epitope-targeted peptides., JingXin Liang, David N Bunck, Anvita Mishra, Sunga Hong, Matthew N Idso, and James R Heath

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Time-dependent saddle-node bifurcation: Breaking time and the point of no return in a non-autonomous model of critical transitions., Jeremiah H Li, Felix X-F Ye, Hong Qian, and Sui Huang

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Transcriptomics and proteomics reveal two waves of translational repression during the maturation of malaria parasite sporozoites., Scott E Lindner, Kristian E Swearingen, Melanie J Shears, Michael P Walker, Erin N Vrana, Kevin J Hart, Allen M Minns, Photini Sinnis, Robert L Moritz, and Stefan H I Kappe

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Genome-wide analysis identifies NR4A1 as a key mediator of T cell dysfunction., Xindong Liu, Yun Wang, Huiping Lu, Jing Li, Xiaowei Yan, Minglu Xiao, Jing Hao, Andrei Alekseev, Hiep Khong, Tenghui Chen, Rui Huang, Jin Wu, Qiwen Zhao, Qi Wu, Senlin Xu, Xiaohu Wang, Wei Jin, Shicang Yu, Yan Wang, Lai Wei, Aibo Wang, Bo Zhong, Ling Ni, Xiaolong Liu, Roza Nurieva, Lilin Ye, Qiang Tian, Xiu-Wu Bian, and Chen Dong

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Liquid biopsy-based single-cell metabolic phenotyping of lung cancer patients for informative diagnostics., Ziming Li, Zhuo Wang, Yin Tang, Xiang Lu, Jie Chen, Yu Dong, Baojun Wu, Chunying Wang, Liu Yang, Zhili Guo, Min Xue, Shun Lu, Wei Wei, and Qihui Shi

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Objective Evidence of Reflux Control After Magnetic Sphincter Augmentation: One Year Results From a Post Approval Study., Brian Louie, C Daniel Smith, Christopher C Smith, Reginald C W Bell, George Kevin Gillian, Jeffrey S Mandel, Kyle A Perry, Walter Kurt Birkenhagen, Paul A Taiganides, Christy M Dunst, Howard M McCollister, John C Lipham, Leena K Khaitan, Shawn T Tsuda, Blair A Jobe, Shanu N Kothari, and Jon C Gould

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Precision Medicine in Pancreatic Disease-Knowledge Gaps and Research Opportunities: Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop., Mark E Lowe, Dana K Andersen, Richard M Caprioli, Jyoti Choudhary, Zobeida Cruz-Monserrate, Anil K Dasyam, Christopher E Forsmark, Fred S Gorelick, Joe W Gray, Mark Haupt, Kimberly A Kelly, Kenneth P Olive, Sylvia K Plevritis, Noa Rappaport, Holger R Roth, Hanno Steen, S Joshua Swamidass, Temel Tirkes, Aliye Uc, Kirill Veselkov, David C Whitcomb, and Aida Habtezion

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Precision Medicine in Pancreatic Disease-Knowledge Gaps and Research Opportunities: Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop., Mark E Lowe, Dana K Andersen, Richard M Caprioli, Jyoti Choudhary, Zobeida Cruz-Monserrate, Anil K Dasyam, Christopher E Forsmark, Fred S Gorelick, Joe W Gray, Mark Haupt, Kimberly A Kelly, Kenneth P Olive, Sylvia K Plevritis, Noa Rappaport, Holger R Roth, Hanno Steen, S Joshua Swamidass, Temel Tirkes, Aliye Uc, Kirill Veselkov, David C Whitcomb, and Aida Habtezion

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Identification of Cross-linked Peptides Using Isotopomeric Cross-linkers., Jie Luo, Jacob Bassett, and Jeff Ranish

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4D electron microscopy of T cell activation., Yue Lu, Byung-Kuk Yoo, Alphonsus H C Ng, Jungwoo Kim, Sinchul Yeom, Jau Tang, Milo M Lin, Ahmed H Zewail, and James R Heath

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4D electron microscopy of T cell activation., Yue Lu, Byung-Kuk Yoo, Alphonsus H C Ng, Jungwoo Kim, Sinchul Yeom, Jau Tang, Milo M Lin, Ahmed H Zewail, and James R Heath

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Reproducible big data science: A case study in continuous FAIRness., Ravi Madduri, Kyle Chard, Mike D'Arcy, Segun C Jung, Alexis Rodriguez, Dinanath Sulakhe, Eric W Deutsch, Cory C Funk, Ben Heavner, Matthew A Richards, Paul Shannon, Gustavo Glusman, Nathan D Price, Carl Kesselman, and Ian Foster

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Incorporating a Detailed Case Log System to Standardize Robotic Colon and Rectal Surgery Resident Training and Performance Evaluation., Rachel Martin, June Hsu, Mark K Soliman, Amir Bastawrous, and Robert K Cleary

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Efficacy of Therapies Following Venetoclax Discontinuation in CLL: Focus on B-Cell Receptor Signal Transduction Inhibitors and Cellular Therapies, Anthony R. Mato, Neil Bailey, and See full list of authors in comments

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Sex differences in cardiac function, biomarkers and exercise performance in heart failure with preserved ejection fraction: findings from the RELAX trial., Rina Mauricio, Kershaw V Patel, Vijay Agusala, Kavisha Singh, Alana Lewis, Colby Ayers, Justin L Grodin, Jarett D Berry, and Ambarish Pandey

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Influenza A Reinfection in Sequential Human Challenge: Implications for Protective Immunity and "Universal" Vaccine Development., Matthew J Memoli, Alison Han, Kathie-Anne Walters, Lindsay Czajkowski, Susan Reed, Rani Athota, Luz Angela Rosas, Adriana Cervantes-Medina, Jae-Keun Park, David M Morens, John C Kash, and Jeffery K Taubenberger

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MITF has a central role in regulating starvation-induced autophagy in melanoma., Katrin Möller, Sara Sigurbjornsdottir, Asgeir O Arnthorsson, Vivian Pogenberg, Ramile Dilshat, Valerie Fock, Solveig H Brynjolfsdottir, Christian Bindesboll, Margret Bessadottir, Helga M Ogmundsdottir, Anne Simonsen, Lionel Larue, Matthias Wilmanns, Vesteinn Thorsson, Eirikur Steingrimsson, and Margret H Ogmundsdottir

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Epidemiologic features of a large hepatitis C cohort evaluated in a major health system in the western United States., Nizar A Mukhtar, Erik M Ness, Manan Jhaveri, Oren K Fix, Marquis Hart, Christopher Dale, Cheryl Pratt, and Kris V Kowdley

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Systems Pharmacogenomic Landscape of Drug Similarities from LINCS data: Drug Association Networks., Aliyu Musa, Shailesh Tripathi, Matthias Dehmer, Olli Yli-Harja, Stuart A Kauffman, and Frank Emmert-Streib

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Publisher Correction: Toxoplasma Modulates Signature Pathways of Human Epilepsy, Neurodegeneration & Cancer., Huân M Ngô, Ying Zhou, Hernan Lorenzi, Kai Wang, Taek-Kyun Kim, Yong Zhou, Kamal El Bissati, Ernest Mui, Laura Fraczek, Seesandra V Rajagopala, Craig W Roberts, Fiona L Henriquez, Alexandre Montpetit, Jenefer M Blackwell, Sarra E Jamieson, Kelsey Wheeler, Ian J Begeman, Carlos Naranjo-Galvis, Ney Alliey-Rodriguez, Roderick G Davis, Liliana Soroceanu, Charles Cobbs, Dennis A Steindler, Kenneth Boyer, A Gwendolyn Noble, Charles N Swisher, Peter T Heydemann, Peter Rabiah, Shawn Withers, Patricia Soteropoulos, Leroy Hood, and Rima McLeod

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BiGG Models 2020: multi-strain genome-scale models and expansion across the phylogenetic tree., Charles J Norsigian, Neha Pusarla, John Luke McConn, James T Yurkovich, Andreas Dräger, Bernhard O Palsson, and Zachary King

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Development and validation of a web-based electronic application in managing antithrombotic agents in patients undergoing GI endoscopy., Venkat Nutalapati, Krishna Teja Tokala, Madhav Desai, Vijay Kanakadandi, Mojtaba Olyaee, Sravanthi Parasa, and Amit Rastogi

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Single-Cell Glia and Neuron Gene Expression in the Central Amygdala in Opioid Withdrawal Suggests Inflammation With Correlated Gut Dysbiosis., Sean J O'Sullivan, Evangelia Malahias, James Park, Ankita Srivastava, Beverly A S Reyes, Jon Gorky, Rajanikanth Vadigepalli, Elisabeth J Van Bockstaele, and James S Schwaber

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Advances in Identifying and Characterizing the Human Proteome., Young-Ki Paik, Christopher M Overall, Fernando Corrales, Eric W Deutsch, Lydie Lane, and Gilbert S Omenn

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Advances in Identifying and Characterizing the Human Proteome., Young-Ki Paik, Christopher M Overall, Fernando Corrales, Eric W Deutsch, Lydie Lane, and Gilbert S Omenn

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Single-Cell Proteomics Reveal that Quantitative Changes in Co-expressed Lineage-Specific Transcription Factors Determine Cell Fate., Carmen G Palii, Qian Cheng, Mark A Gillespie, Paul Shannon, Michalina Mazurczyk, Giorgio Napolitani, Nathan D Price, Jeffrey A Ranish, Edward Morrissey, Douglas R Higgs, and Marjorie Brand

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Preoperative stimulation of resolution and inflammation blockade eradicates micrometastases., Dipak Panigrahy, Allison Gartung, Jun Yang, Haixia Yang, Molly M Gilligan, Megan L Sulciner, Swati S Bhasin, Diane R Bielenberg, Jaimie Chang, Birgitta A Schmidt, Julia Piwowarski, Anna Fishbein, Dulce Soler-Ferran, Matthew A Sparks, Steven J Staffa, Vidula Sukhatme, Bruce D Hammock, Mark W Kieran, Sui Huang, Manoj Bhasin, Charles N Serhan, and Vikas P Sukhatme

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Preoperative stimulation of resolution and inflammation blockade eradicates micrometastases., Dipak Panigrahy, Allison Gartung, Jun Yang, Haixia Yang, Molly M Gilligan, Megan L Sulciner, Swati S Bhasin, Diane R Bielenberg, Jaimie Chang, Birgitta A Schmidt, Julia Piwowarski, Anna Fishbein, Dulce Soler-Ferran, Matthew A Sparks, Steven J Staffa, Vidula Sukhatme, Bruce D Hammock, Mark W Kieran, Sui Huang, Manoj Bhasin, Charles N Serhan, and Vikas P Sukhatme

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MicroRNA-transcriptome networks in whole blood and monocytes of women undergoing preterm labour., Alison G Paquette, Oksana Shynlova, Xiaogang Wu, Mark Kibschull, Kai Wang, Nathan D Price, and Stephen J Lye

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Estimating neoplasia detection rate (NDR) in patients with Barrett's oesophagus based on index endoscopy: a systematic review and meta-analysis., Sravanthi Parasa, Madhav Desai, Anusha Vittal, Viveksandeep T Chandrasekar, Asad Pervez, Kevin F Kennedy, Neil Gupta, Nicholas J Shaheen, and Prateek Sharma

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Architecture of the chromatin remodeler RSC and insights into its nucleosome engagement., Avinash B Patel, Camille M Moore, Basil J Greber, Jie Luo, Stefan A Zukin, Jeff Ranish, and Eva Nogales

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Genome-Scale Transcriptional Regulatory Network Models of Psychiatric and Neurodegenerative Disorders., Jocelynn R Pearl, Carlo Colantuoni, Dani E Bergey, Cory C Funk, Paul Shannon, Bijoya Basu, Alex M Casella, Rediet T Oshone, Leroy Hood, Nathan D Price, and Seth A Ament

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Sensitive Detection and Analysis of Neoantigen-Specific T Cell Populations from Tumors and Blood., Songming Peng, Jesse M Zaretsky, Alphonsus H C Ng, William Chour, Michael T Bethune, Jongchan Choi, Alice Hsu, Elizabeth Holman, Xiaozhe Ding, Katherine Guo, Jungwoo Kim, Alexander M Xu, John E Heath, Won Jun Noh, Jing Zhou, Yapeng Su, Yue Lu, Jami McLaughlin, Donghui Cheng, Owen N Witte, David Baltimore, Antoni Ribas, and James R Heath

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Path-seq identifies an essential mycolate remodeling program for mycobacterial host adaptation., Eliza Jr Peterson, Rebeca Bailo, Alissa C Rothchild, Mario L Arrieta-Ortiz, Amardeep Kaur, Min Pan, Dat Mai, Abrar A Abidi, Charlotte Cooper, Alan Aderem, Apoorva Bhatt, and Nitin S Baliga

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Absence of full-length dystrophin impairs normal maturation and contraction of cardiomyocytes derived from human induced pluripotent stem cells., J Manuel Pioner, Xuan Guan, Jordan M Klaiman, Alice W Racca, Lil Pabon, Veronica Muskheli, Jesse Macadangdang, Cecilia Ferrantini, Michael R Hoopmann, Robert L Moritz, Deok-Ho Kim, Chiara Tesi, Corrado Poggesi, Charles E Murry, Martin K Childers, David L Mack, and Michael Regnier

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A Pan-Cancer Approach to Predict Responsiveness to Immune Checkpoint Inhibitors by Machine Learning., Maurizio Polano, Marco Chierici, Michele Dal Bo, Davide Gentilini, Federica Di Cintio, Lorena Baboci, David L Gibbs, Cesare Furlanello, and Giuseppe Toffoli

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A library of human gut bacterial isolates paired with longitudinal multiomics data enables mechanistic microbiome research., M Poyet, M Groussin, S M Gibbons, J Avila-Pacheco, X Jiang, S M Kearney, A R Perrotta, B Berdy, S Zhao, T D Lieberman, P K Swanson, M Smith, S Roesemann, J E Alexander, S A Rich, J Livny, H Vlamakis, C Clish, K Bullock, A Deik, J Scott, K A Pierce, R J Xavier, and E J Alm

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Gene annotation errors are common in the mammalian mitochondrial genomes database., Carlos F Prada and Jeffrey L Boore

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Spatial presentation of biological molecules to cells by localized diffusive transfer., Mary C Regier, Emily Olszewski, Christoph C Carter, John D Aitchison, Alexis Kaushansky, Jennifer Davis, Erwin Berthier, David J Beebe, and Kelly R Stevens

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Provider Attitudes and Practice Patterns for Direct-Acting Antiviral Therapy for Patients with Hepatocellular Carcinoma., Nicole E Rich, Ju Dong Yang, Ponni V Perumalswami, Naim Alkhouri, Whitney Jackson, Neehar D Parikh, Neil Mehta, Reena Salgia, Andres Duarte-Rojo, Laura Kulik, Mina Rakoski, Adnan Said, Omobonike Oloruntoba, George N Ioannou, Maarouf A Hoteit, Andrew M Moon, Amol S Rangnekar, Sheila L Eswaran, Elizabeth Zheng, Janice H Jou, James Hanje, Anjana Pillai, Ruben Hernaez, Robert Wong, Steven Scaglione, Hrishikesh Samant, Devika Kapuria, Shaun Chandna, Russell Rosenblatt, Veeral Ajmera, Catherine Frenette, Sanjaya K Satapathy, Parvez Mantry, Prasun Jalal, Binu V John, Oren K Fix, Michael Leise, Christina C Lindenmeyer, Avegail Flores, Nayan Patel, Z Gordon Jiang, Nyan Latt, Renumathy Dhanasekaran, Mobolaji Odewole, Sofia Kagan, Jorge A Marrero, and Amit G Singal

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Impaired HDL Metabolism Links GlycA, A Novel Inflammatory Marker, with Incident Cardiovascular Events., Kayla A Riggs, Parag H Joshi, Amit Khera, Kavisha Singh, Oludamilola Akinmolayemi, Colby R Ayers, and Anand Rohatgi

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Opportunities and Challenges in Interpreting and Sharing Personal Genomes., Irit R Rubin and Gustavo Glusman

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In vivo proteomics identifies the competence regulon and AliB oligopeptide transporter as pathogenic factors in pneumococcal meningitis., Frank Schmidt, Niamatullah Kakar, Tanja C Meyer, Maren Depke, Ilias Masouris, Gerhard Burchhardt, Alejandro Gómez-Mejia, Vishnu Dhople, Leiv S Håvarstein, Zhi Sun, Robert L Moritz, Uwe Völker, Uwe Koedel, and Sven Hammerschmidt

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Incorporating In-Source Fragments Improves Metabolite Identification Accuracy in Untargeted LCMS and LCMS/MS Datasets., Brian C Searle, Jacob C Lippincott, and Phillip M Seitzer

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An efficient solution for resolving iTRAQ and TMT channel crosstalk., Brian C Searle and Alfred L Yergey

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Downregulation of CENPF Remodels Prostate Cancer Cells and Alters Cellular Metabolism., Muhammad Shahid, Minhyung Kim, Min Young Lee, Austin Yeon, Sungyong You, Hyung L Kim, and Jayoung Kim

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Downregulation of CENPF Remodels Prostate Cancer Cells and Alters Cellular Metabolism., Muhammad Shahid, Minhyung Kim, Min Young Lee, Austin Yeon, Sungyong You, Hyung L Kim, and Jayoung Kim

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Proteomic Analysis of Plasmodium Merosomes: The Link between Liver and Blood Stages in Malaria., Melanie J Shears, Raja Sekhar Nirujogi, Kristian E Swearingen, Santosh Renuse, Satish Mishra, Panga Jaipal Reddy, Robert L Moritz, Akhilesh Pandey, and Photini Sinnis

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OptRAM: In-silico strain design via integrative regulatory-metabolic network modeling., Fangzhou Shen, Renliang Sun, Jie Yao, Jian Li, Qian Liu, Nathan D Price, Chenguang Liu, and Zhuo Wang

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PTMProphet: Fast and Accurate Mass Modification Localization for the Trans-Proteomic Pipeline., David Shteynberg, Eric W Deutsch, David S Campbell, Michael R Hoopmann, Ulrike Kusebauch, Dave Lee, Luis Mendoza, Mukul K Midha, Zhi Sun, Anthony D Whetton, and Robert L Moritz

Differential Associations Between Novel HDL Markers and Incident Atherosclerotic Cardiovascular Disease by Gender, Race and Vascular Territory: A Pooled Cohort Analysis, Kavisha Singh and et al

Ivabradine Toxicity: Setting the Pace for the Heart, Kavisha Singh and et al

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Abstract 688: Differential Associations Between Novel HDL Markers and Incident Atherosclerotic Cardiovascular Disease by Gender and Vascular Territory: A Meta-analysis of Large Population-based Cohorts, Kavisha Singh, Colby Ayers, and Anand Rohatgi

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Mechanistic inferences on metabolic dysfunction in PTSD from an integrated model and multi-omic analysis: Role of glucocorticoid receptor sensitivity., Pramod R Somvanshi, Synthia H Mellon, Janine D Flory, Duna Abu-Amara, Ptsd Systems Biology Consortium, Owen M Wolkowitz, Rachel Yehuda, Marti Jett, Leroy Hood, Charles Marmar, and Francis J Doyle

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Dance class for people with Parkinson's is 'what our body needs', Tad Sooter and Nancy B. Isenberg (interviewee)

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Phenotypic heterogeneity and evolution of melanoma cells associated with targeted therapy resistance., Yapeng Su, Marcus Bintz, Yezi Yang, Lidia Robert, Alphonsus H C Ng, Victoria Liu, Antoni Ribas, James R Heath, and Wei Wei

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A Tandem Mass Spectrometry Sequence Database Search Method for Identification of O-Fucosylated Proteins by Mass Spectrometry., Kristian E Swearingen, Jimmy K Eng, David Shteynberg, Vladimir Vigdorovich, Timothy A Springer, Luis Mendoza, D Noah Sather, Eric W Deutsch, Stefan H I Kappe, and Robert L Moritz

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Circulatory metastin/kisspeptin-1 in polycystic ovary syndrome: a systematic review and meta-analysis with diagnostic test accuracy., Seshadri Reddy Varikasuvu, V Satya Prasad, V C Vamshika, M V Satyanarayana, and Panga Jaipal Reddy

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Circulating Angiopoietin-like 8 protein (ANGPTL8/Betatrophin) in patients with polycystic ovary syndrome: a systematic review and multi effect size meta-analysis., Seshadri Reddy Varikasuvu, Panga Jaipal Reddy, and M V Satyanarayana

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Plasmodium Secretion Induces Hepatocyte Lysosome Exocytosis and Promotes Parasite Entry., Kamalakannan Vijayan, Igor Cestari, Fred D Mast, Elizabeth K K Glennon, Suzanne M McDermott, Heather S Kain, Alyssa M Brokaw, John D Aitchison, Kenneth Stuart, and Alexis Kaushansky

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2-(2-(2,4-dioxopentan-3-ylidene)hydrazineyl)benzonitrile as novel inhibitor of receptor tyrosine kinase and PI3K/AKT/mTOR signaling pathway in glioblastoma., Anisha Viswanathan, Dinesh Kute, Aliyu Musa, Saravanan Konda Mani, Vili Sipilä, Frank Emmert-Streib, Fedor I Zubkov, Atash V Gurbanov, Olli Yli-Harja, and Meenakshisundaram Kandhavelu

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Battling Glioblastoma: A Novel Tyrosine Kinase Inhibitor with Multi-Dimensional Anti-Tumor Effect (Running Title: Cancer Cells Death Signalling Activation)., Anisha Viswanathan, Aliyu Musa, Akshaya Murugesan, João R Vale, Carlos A M Afonso, Saravanan Konda Mani, Olli Yli-Harja, Nuno R Candeias, and Meenakshisundaram Kandhavelu

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The Human Immunopeptidome Project: a roadmap to predict and treat immune diseases., Juan Antonio Vizcaíno, Peter Kubiniok, Kevin Kovalchik, Qing Ma, Jérôme Despault Duquette, Ian Mongrain, Eric W Deutsch, Bjoern Peters, Alessandro Sette, Isabelle Sirois, and Etienne Caron

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A Simple Measure of Hepatocellular Carcinoma Burden Predicts Tumor Recurrence after Liver Transplantation: The RH-IML Classification., Philip Vutien, Jennifer Dodge, Kiran M Bambha, Eric M Nordstrom, Jane Gralla, Kristen Campbell, Claire Levek, Trevor Nydam, Oren Fix, George Ioannou, and Scott W Biggins

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A Simple Measure of Hepatocellular Carcinoma Burden Predicts Tumor Recurrence After Liver Transplantation: The Recurrent Hepatocellular Carcinoma-Initial, Maximum, Last Classification., Philip Vutien, Jennifer Dodge, Kiran M Bambha, Eric M Nordstrom, Jane Gralla, Kristen Campbell, Claire Levek, Trevor Nydam, Oren K Fix, George Ioannou, and Scott W Biggins

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Differential Effects of Influenza Virus NA, HA Head, and HA Stalk Antibodies on Peripheral Blood Leukocyte Gene Expression during Human Infection., Kathie-Anne Walters, Ruoqing Zhu, Michael Welge, Kelsey Scherler, Jae-Keun Park, Zainab Rahil, Hao Wang, Loretta Auvil, Colleen Bushell, Min Young Lee, David Baxter, Tyler Bristol, Luz Angela Rosas, Adriana Cervantes-Medina, Lindsay Czajkowski, Alison Han, Matthew J Memoli, Jeffery K Taubenberger, and John C Kash

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Special Issue on Software Tools and Resources: Acknowledging the Toolmakers of Science., Susan T Weintraub, Michael R Hoopmann, and Magnus Palmblad

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Special Issue on Single-Cell Multiomics for Immuno-Oncology and Cancer Systems Biology., Wei Wei and Rong Fan

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Buparlisib in Patients With Recurrent Glioblastoma Harboring Phosphatidylinositol 3-Kinase Pathway Activation: An Open-Label, Multicenter, Multi-Arm, Phase II Trial., Patrick Y Wen, Mehdi Touat, Brian M Alexander, Ingo K Mellinghoff, Shakti Ramkissoon, Christine S McCluskey, Kristine Pelton, Sam Haidar, Sankha S Basu, Sarah C Gaffey, Loreal E Brown, Juan Emmanuel Martinez-Ledesma, Shaofang Wu, Jungwoo Kim, Wei Wei, Mi-Ae Park, Jason T Huse, John G Kuhn, Mikael L Rinne, Howard Colman, Nathalie Y R Agar, Antonio M Omuro, Lisa M DeAngelis, Mark R Gilbert, John F de Groot, Timothy F Cloughesy, Andrew S Chi, Thomas M Roberts, Jean J Zhao, Eudocia Q Lee, Lakshmi Nayak, James R Heath, Laura L Horky, Tracy T Batchelor, Rameen Beroukhim, Susan M Chang, Azra H Ligon, Ian F Dunn, Dimpy Koul, Geoffrey S Young, Michael D Prados, David A Reardon, W K Alfred Yung, and Keith L Ligon

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Buparlisib in Patients With Recurrent Glioblastoma Harboring Phosphatidylinositol 3-Kinase Pathway Activation: An Open-Label, Multicenter, Multi-Arm, Phase II Trial., Patrick Y Wen, Mehdi Touat, Brian M Alexander, Ingo K Mellinghoff, Shakti Ramkissoon, Christine S McCluskey, Kristine Pelton, Sam Haidar, Sankha S Basu, Sarah C Gaffey, Loreal E Brown, Juan Emmanuel Martinez-Ledesma, Shaofang Wu, Jungwoo Kim, Wei Wei, Mi-Ae Park, Jason T Huse, John G Kuhn, Mikael L Rinne, Howard Colman, Nathalie Y R Agar, Antonio M Omuro, Lisa M DeAngelis, Mark R Gilbert, John F de Groot, Timothy F Cloughesy, Andrew S Chi, Thomas M Roberts, Jean J Zhao, Eudocia Q Lee, Lakshmi Nayak, James R Heath, Laura L Horky, Tracy T Batchelor, Rameen Beroukhim, Susan M Chang, Azra H Ligon, Ian F Dunn, Dimpy Koul, Geoffrey S Young, Michael D Prados, David A Reardon, W K Alfred Yung, and Keith L Ligon

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Blood metabolome predicts gut microbiome α-diversity in humans., Tomasz Wilmanski, Noa Rappaport, John C Earls, Andrew T Magis, Ohad Manor, Jennifer Lovejoy, Gilbert S Omenn, Leroy Hood, Sean M Gibbons, and Nathan D Price

Lung cancer screening: Implementation in a multi-state, community-based setting The International Association for the Study of Lung Cancer 20th World Conference on Lung Cancer Barcelona, CL Wilshire

Relationship between lung cancer screening centers in the United States and high-risk individuals The International Association for the Study of Lung Cancer 20th World Conference on Lung Cancer Barcelona, Spain, CL Wilshire

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Proximate grassland and shrub-encroached sites show dramatic restructuring of soil bacterial communities., Xingjia Xiang, Sean M Gibbons, He Li, Haihua Shen, and Haiyan Chu

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Small Molecule KRAS Agonist for Mutant KRAS Cancer Therapy., Ke Xu, Dongkyoo Park, Andrew T Magis, Jun Zhang, Wei Zhou, Gabriel L Sica, Suresh S Ramalingam, Walter J Curran, and Xingming Deng

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Toxicities and Outcomes of Acalabrutinib-Treated Patients with Chronic Lymphocytic Leukemia: A Retrospective Analysis of Real World Patients, Maryam Sarraf Yazdy, John M Pagel, Neil Bailey, Krish Patel, and See full list of authors in comments

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How Many Nodes Need to be Removed to Make Esophagectomy an Adequate Cancer Operation, and Does the Number Change When a Patient has Chemoradiotherapy Before Surgery?, Jonathan C Yeung, Manjit S Bains, Arianna Barbetta, Tamar Nobel, Steven R DeMeester, Brian E Louie, Mark B Orringer, Linda W Martin, Rishindra M Reddy, Francisco Schlottmann, and Daniela Molena

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Blood Is a Window into Health and Disease., James T Yurkovich and Leroy Hood

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A systems approach to clinical oncology uses deep phenotyping to deliver personalized care., James T Yurkovich, Qiang Tian, Nathan D Price, and Leroy Hood

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EcoFABs: advancing microbiome science through standardized fabricated ecosystems., Karsten Zengler, Kirsten Hofmockel, Nitin Baliga, Scott W Behie, Hans C Bernstein, James B Brown, José R Dinneny, Sheri A Floge, Samuel P Forry, Matthias Hess, Scott A Jackson, Christer Jansson, Stephen R Lindemann, Jennifer Pett-Ridge, Costas Maranas, Ophelia S Venturelli, Matthew D Wallenstein, Elizabeth A Shank, and Trent R Northen

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Survivin is a prognostic marker and therapeutic target for extranodal, nasal-type natural killer/T cell lymphoma., Li Zhang, Yi Wei, Xiaowei Yan, Na Li, Haolan Song, Li Yang, Yang Wu, Yu-Feng Xi, Hua-Wei Weng, Jian-Hua Li, Edward H Lin, and Li-Qun Zou

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Adaptive Evolution within Gut Microbiomes of Healthy People., Shijie Zhao, Tami D Lieberman, Mathilde Poyet, Kathryn M Kauffman, Sean M Gibbons, Mathieu Groussin, Ramnik J Xavier, and Eric J Alm

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Evaluation of Stein-O'Brien et al.: To See a World in a Grain of Sand-How to Reveal a Common Latent Space through Multiple Platform Omics Data., Joseph X Zhou

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Development of Hematopoietic Stem Cell-Engineered Invariant Natural Killer T Cell Therapy for Cancer., Yanni Zhu, Drake J Smith, Yang Zhou, Yan-Ruide Li, Jiaji Yu, Derek Lee, Yu-Chen Wang, Stefano Di Biase, Xi Wang, Christian Hardoy, Josh Ku, Tasha Tsao, Levina J Lin, Alexander T Pham, Heesung Moon, Jami McLaughlin, Donghui Cheng, Roger P Hollis, Beatriz Campo-Fernandez, Fabrizia Urbinati, Liu Wei, Larry Pang, Valerie Rezek, Beata Berent-Maoz, Mignonette H Macabali, David Gjertson, Xiaoyan Wang, Zoran Galic, Scott G Kitchen, Dong Sung An, Siwen Hu-Lieskovan, Paula J Kaplan-Lefko, Satiro N De Oliveira, Christopher S Seet, Sarah M Larson, Stephen J Forman, James R Heath, Jerome A Zack, Gay M Crooks, Caius G Radu, Antoni Ribas, Donald B Kohn, Owen N Witte, and Lili Yang

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Genetic Predisposition Impacts Clinical Changes in a Lifestyle Coaching Program., Niha Zubair, Matthew P Conomos, Leroy Hood, Gilbert S Omenn, Nathan D Price, Bonnie J Spring, Andrew T Magis, and Jennifer C Lovejoy

Submissions from 2018

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Cell death as a trigger for morphogenesis., Boris Aguilar, Ahmadreza Ghaffarizadeh, Christopher D Johnson, Gregory J Podgorski, Ilya Shmulevich, and Nicholas S Flann