Providence research from Washington locations.

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Submissions from 2018

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Systematic Analysis of Splice-Site-Creating Mutations in Cancer., Reyka G Jayasinghe, Song Cao, Qingsong Gao, Michael C Wendl, Nam Sy Vo, Sheila M Reynolds, Yanyan Zhao, Héctor Climente-González, Shengjie Chai, Fang Wang, Rajees Varghese, Mo Huang, Wen-Wei Liang, Matthew A Wyczalkowski, Sohini Sengupta, Zhi Li, Samuel H Payne, David Fenyö, Jeffrey H Miner, Matthew J Walter, Benjamin Vincent, Eduardo Eyras, Ken Chen, Ilya Shmulevich, Feng Chen, and Li Ding

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Novel metrics for quantifying bacterial genome composition skews., Lena M Joesch-Cohen, Max Robinson, Neda Jabbari, Christopher G Lausted, and Gustavo Glusman

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Determining Relative Dynamic Stability of Cell States Using Boolean Network Model., Jae Il Joo, Joseph X Zhou, Sui Huang, and Kwang-Hyun Cho

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An RNAi screen in human cell lines reveals conserved DNA damage repair pathways that mitigate formaldehyde sensitivity., Eleonora Juarez, Nyasha Chambwe, Weiliang Tang, Asia D Mitchell, Nichole Owen, Anuradha Kumari, Raymond J Monnat, and Amanda K McCullough

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Emergence of diversity in homogeneous coupled Boolean networks., Chris Kang, Boris Aguilar, and Ilya Shmulevich

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Management of complex pleural space infections: as the pendulum swings The American Association for Thoracic Surgery 98th Annual Meeting Resident Poster Competition San Diego, California, NM Kanodra, Candice L. Wilshire, and See all authors in comments

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MAMMOTh: A new database for curated mathematical models of biomolecular systems., Fedor Kazantsev, Ilya Akberdin, Sergey Lashin, Natalia Ree, Vladimir Timonov, Alexander Ratushny, Tamara Khlebodarova, and Vitaly Likhoshvai

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The building blocks of successful translation of proteomics to the clinic., Paul Kearney, J Jay Boniface, Nathan D Price, and Leroy Hood

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Serum lipidomic analysis for the discovery of biomarkers for major depressive disorder in drug-free patients., Eun Young Kim, Jae Won Lee, Min Young Lee, Se Hyun Kim, Hyuck Jun Mok, Kyooseob Ha, Yong Min Ahn, and Kwang Pyo Kim

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Integrative structure and functional anatomy of a nuclear pore complex., Seung Joong Kim, Javier Fernandez-Martinez, Ilona Nudelman, Yi Shi, Wenzhu Zhang, Barak Raveh, Thurston Herricks, Brian D Slaughter, Joanna A Hogan, Paula Upla, Ilan E Chemmama, Riccardo Pellarin, Ignacia Echeverria, Manjunatha Shivaraju, Azraa S Chaudhury, Junjie Wang, Rosemary Williams, Jay R Unruh, Charles H Greenberg, Erica Y Jacobs, Zhiheng Yu, M Jason de la Cruz, Roxana Mironska, David L Stokes, John D Aitchison, Martin F Jarrold, Jennifer L Gerton, Steven J Ludtke, Christopher W Akey, Brian T Chait, Andrej Sali, and Michael P Rout

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ProbAnnoWeb and ProbAnnoPy: probabilistic annotation and gap-filling of metabolic reconstructions., Brendan King, Terry Farrah, Matthew A Richards, Michael Mundy, Evangelos Simeonidis, and Nathan D Price

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Molecular structure of promoter-bound yeast TFIID., Olga Kolesnikova, Adam Ben-Shem, Jie Luo, Jeff Ranish, Patrick Schultz, and Gabor Papai

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Selected reaction monitoring mass spectrometry of mastitis milk reveals pathogen-specific regulation of bovine host response proteins., Ulrike Kusebauch, Lorenzo E Hernández-Castellano, Stine L Bislev, Robert L Moritz, Christine M Røntved, and Emøke Bendixen

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Predicting Low-Risk for Sustained Alcohol Use After Early Liver Transplant for Acute Alcoholic Hepatitis: The SALT Score., Brian P Lee, Eric Vittinghoff, Christine Hsu, Hyosun Han, George Therapondos, Oren K Fix, David W Victor, Deepti Dronamraju, Gene Y Im, Michael D Voigt, John P Rice, Michael R Lucey, Sheila Eswaran, Po-Hung Chen, Zhiping Li, Haripriya Maddur, and Norah A Terrault

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ABRF Proteome Informatics Research Group (iPRG) 2016 Study: Inferring Proteoforms from Bottom-up Proteomics Data., Joon-Yong Lee, Hyungwon Choi, Christopher M Colangelo, Darryl Davis, Michael R Hoopmann, Lukas Käll, Henry Lam, Samuel H Payne, Yasset Perez-Riverol, Matthew The, Ryan Wilson, Susan T Weintraub, and Magnus Palmblad

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Surface Immobilization of Redox-Labile Fluorescent Probes: Enabling Single-Cell Co-Profiling of Aerobic Glycolysis and Oncogenic Protein Signaling Activities., Zhonghan Li, Hanjun Cheng, Shiqun Shao, Xiang Lu, Li Mo, Jonathan Tsang, Pu Zeng, Zhili Guo, Siwen Wang, David A Nathanson, James R Heath, Wei Wei, and Min Xue

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Reply to "Precision medicine in the clouds"., Andrew T Magis, John C Earls, Gustavo Glusman, Gilbert S Omenn, Jennifer C Lovejoy, Nathan D Price, and Leroy Hood

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The Iceman's Last Meal Consisted of Fat, Wild Meat, and Cereals., Frank Maixner, Dmitrij Turaev, Amaury Cazenave-Gassiot, Marek Janko, Ben Krause-Kyora, Michael R Hoopmann, Ulrike Kusebauch, Mark Sartain, Gea Guerriero, Niall O'Sullivan, Matthew Teasdale, Giovanna Cipollini, Alice Paladin, Valeria Mattiangeli, Marco Samadelli, Umberto Tecchiati, Andreas Putzer, Mine Palazoglu, John Meissen, Sandra Lösch, Philipp Rausch, John F Baines, Bum Jin Kim, Hyun-Joo An, Paul Gostner, Eduard Egarter-Vigl, Peter Malfertheiner, Andreas Keller, Robert W Stark, Markus Wenk, David Bishop, Daniel G Bradley, Oliver Fiehn, Lars Engstrand, Robert L Moritz, Philip Doble, Andre Franke, Almut Nebel, Klaus Oeggl, Thomas Rattei, Rudolf Grimm, and Albert Zink

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mRNA transcript distribution bias between Borrelia burgdorferi bacteria and their outer membrane vesicles., Anjali Malge, Vikas Ghai, Panga Jaipal Reddy, David Baxter, Taek-Kyun Kim, Robert L Moritz, and Kai Wang

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A Multi-omic Association Study of Trimethylamine N-Oxide., Ohad Manor, Niha Zubair, Matthew P Conomos, Xiaojing Xu, Jesse E Rohwer, Cynthia E Krafft, Jennifer C Lovejoy, and Andrew T Magis

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Anticancer activity study of A, Gabriella Marucci, Claudia Santinelli, Michela Buccioni, Aleix Martí Navia, Catia Lambertucci, Anastasia Zhurina, Olli Yli-Harja, Rosaria Volpini, and Meenakshisundaram Kandhavelu

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Modular Organization and Assembly of SWI/SNF Family Chromatin Remodeling Complexes., Nazar Mashtalir, Andrew R D'Avino, Brittany C Michel, Jie Luo, Joshua Pan, Jordan E Otto, Hayley J Zullow, Zachary M McKenzie, Rachel L Kubiak, Roodolph St Pierre, Alfredo M Valencia, Steven J Poynter, Seth H Cassel, Jeffrey A Ranish, and Cigall Kadoch

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Characterization of Peroxisomal Regulation Networks., Fred D Mast and John D Aitchison

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ESCRT-III is required for scissioning new peroxisomes from the endoplasmic reticulum., Fred D Mast, Thurston Herricks, Kathleen M Strehler, Leslie R Miller, Ramsey A Saleem, Richard A Rachubinski, and John D Aitchison

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Does treatment of the hiatus influence the outcomes of magnetic sphincter augmentation for chronic GERD? The Society of Surgery of the Alimentary Tract, 59th Annual Meeting Digestive Diseases Week, M Matias, S Blitz, Candice L. Wilshire, AS Jackson, AS Farivar, RW Aye, CM Dunst, and BE Louie

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Venetoclax As Monotherapy or in Combination: Patterns of Use and Predictors of Outcomes in an International Multicenter Study of CLL Patients, Anthony R. Mato, John M Pagel, Neil Bailey, and See all authors in comments

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Allosteric Inhibitor of KRas Identified Using a Barcoded Assay Microchip Platform., Amy M McCarthy, Jungwoo Kim, A Katrine Museth, Ryan K Henning, John E Heath, Emma Winson, Joseph J Oh, Jingxin Liang, Sunga Hong, and James R Heath

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Analysis and visualization of linked molecular and clinical cancer data by using Oncoscape., Lisa G McFerrin, Michael Zager, Jianan Zhang, Gretchen Krenn, Robert McDermott, Desert Horse-Grant, Emily Silgard, Kara Colevas, Paul Shannon, Hamid Bolouri, and Eric C Holland

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Flexible and Fast Mapping of Peptides to a Proteome with ProteoMapper., Luis Mendoza, Eric W Deutsch, Zhi Sun, David S Campbell, David Shteynberg, and Robert L Moritz

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The proBAM and proBed standard formats: enabling a seamless integration of genomics and proteomics data., Gerben Menschaert, Xiaojing Wang, Andrew R Jones, Fawaz Ghali, David Fenyö, Volodimir Olexiouk, Bing Zhang, Eric W Deutsch, Tobias Ternent, and Juan Antonio Vizcaíno

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Targeting TWIST1 through loss of function inhibits tumorigenicity of human glioblastoma., Andrei M Mikheev, Svetlana A Mikheeva, Liza J Severs, Cory C Funk, Lei Huang, José L McFaline-Figueroa, Jeanette Schwensen, Cole Trapnell, Nathan D Price, Stephen Wong, and Robert C Rostomily

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Partnership Between Islam and Palliative Care at Swedish Health Services, Hodo Mohamud, Renee Rassilyer-Bomers, Samantha Bohn, Greg Malone, Hilaire Thompson (Faculty Capstone Project Committee Chair), Eeeseung Byun (Committee Member), and Margaret Heitkemper (Committee Member)

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Simulation Study of cDNA Dataset to Investigate Possible Association of Differentially Expressed Genes of Human THP1-Monocytic Cells in Cancer Progression Affected by Bacterial Shiga Toxins., Syed A Muhammad, Jinlei Guo, Thanh M Nguyen, Xiaogang Wu, Baogang Bai, X Frank Yang, and Jake Y Chen

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Increased levels of RECQ5 shift DNA repair from canonical to alternative pathways., Henry C Olson, Luther Davis, Kostantin Kiianitsa, Kevin J Khoo, Yilun Liu, Theo A Knijnenburg, and Nancy Maizels

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Progress on Identifying and Characterizing the Human Proteome: 2018 Metrics from the HUPO Human Proteome Project., Gilbert S Omenn, Lydie Lane, Christopher M Overall, Fernando J Corrales, Jochen M Schwenk, Young-Ki Paik, Jennifer E Van Eyk, Siqi Liu, Michael Snyder, Mark S Baker, and Eric W Deutsch

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Systems biology approaches towards predictive microbial ecology., Anne E Otwell, Adrián López García de Lomana, Sean M Gibbons, Mónica V Orellana, and Nitin S Baliga

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Transcription Activation Domains of the Yeast Factors Met4 and Ino2: Tandem Activation Domains with Properties Similar to the Yeast Gcn4 Activator., Derek Pacheco, Linda Warfield, Michelle Brajcich, Hannah Robbins, Jie Luo, Jeff Ranish, and Steven Hahn

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Toward Completion of the Human Proteome Parts List: Progress Uncovering Proteins That Are Missing or Have Unknown Function and Developing Analytical Methods., Young-Ki Paik, Christopher M Overall, Fernando Corrales, Eric W Deutsch, Lydie Lane, and Gilbert S Omenn

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Temporal Transcriptomic Analysis of Metabolic Genes in Maternal Organs and Placenta During Murine Pregnancy., Alison Paquette, Priyanka Baloni, Anisa Holloman, Sanjay Nigam, Theo Bammler, Qingcheng Mao, and Nathan D Price

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Comparative transcriptomic analysis of human placentae at term and preterm delivery., Alison G Paquette, Heather M Brockway, Nathan D Price, and Louis J Muglia

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Distinct communication patterns of trophoblastic miRNA among the maternal-placental-fetal compartments., Alison G Paquette, Tianjiao Chu, Xiaogang Wu, Kai Wang, Nathan D Price, and Yoel Sadovsky

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Comparative analysis of gene expression in maternal peripheral blood and monocytes during spontaneous preterm labor., Alison G Paquette, Oksana Shynlova, Mark Kibschull, Nathan D Price, and Stephen J Lye

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Reply., Alison Paquette, Nathan D Price, and Stephen J Lye

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Structure of human TFIID and mechanism of TBP loading onto promoter DNA., Avinash B Patel, Robert K Louder, Basil J Greber, Sebastian Grünberg, Jie Luo, Jie Fang, Yutong Liu, Jeff Ranish, Steve Hahn, and Eva Nogales

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Effects of Delivering SLCO1B1 Pharmacogenetic Information in Randomized Trial and Observational Settings., Bruce Peyser, Emily P Perry, Kavisha Singh, Rosalynn D Gill, Michael R Mehan, Susanne B Haga, Michael D Musty, Nicholas A Milazzo, Dillon Savard, Yi-Ju Li, Gloria Trujilio, and Deepak Voora

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Editorial overview: Systems biology: Data, discovery, delivery., Nathan D Price and Eran Segal

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Stress response of a marine ammonia-oxidizing archaeon informs physiological status of environmental populations., Wei Qin, Shady A Amin, Rachel A Lundeen, Katherine R Heal, Willm Martens-Habbena, Serdar Turkarslan, Hidetoshi Urakawa, Kyle C Costa, Erik L Hendrickson, Tony Wang, David Ac Beck, Sonia M Tiquia-Arashiro, Fred Taub, Andrew D Holmes, Neeraja Vajrala, Paul M Berube, Todd M Lowe, James W Moffett, Allan H Devol, Nitin S Baliga, Daniel J Arp, Luis A Sayavedra-Soto, Murray Hackett, E Virginia Armbrust, Anitra E Ingalls, and David A Stahl

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The Integrated Genomic Landscape of Thymic Epithelial Tumors., Milan Radovich, Curtis R Pickering, Ina Felau, Gavin Ha, Hailei Zhang, Heejoon Jo, Katherine A Hoadley, Pavana Anur, Jiexin Zhang, Mike McLellan, Reanne Bowlby, Thomas Matthew, Ludmila Danilova, Apurva M Hegde, Jaegil Kim, Mark D M Leiserson, Geetika Sethi, Charles Lu, Michael Ryan, Xiaoping Su, Andrew D Cherniack, Gordon Robertson, Rehan Akbani, Paul Spellman, John N Weinstein, D Neil Hayes, Ben Raphael, Tara Lichtenberg, Kristen Leraas, Jean Claude Zenklusen, Junya Fujimoto, Cristovam Scapulatempo-Neto, Andre L Moreira, David Hwang, James Huang, Mirella Marino, Robert Korst, Giuseppe Giaccone, Yesim Gokmen-Polar, Sunil Badve, Arun Rajan, Philipp Ströbel, Nicolas Girard, Ming S Tsao, Alexander Marx, Anne S Tsao, and Patrick J Loehrer

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Referrals for palliative care and hospice are underutilized in patients with advanced non-small cell lung cancer, JR Rayburn, Candice L. Wilshire, CR Gilbert, BE Louie, RW Aye, AS Farivar, E Vallières, and JA Gorden

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Multistate healthcare network underutilizes valuable end-of-life resources in stage IV non-small cell lung cancer, JR Rayburn, Candice L. Wilshire, CR Gilbert, RK Weerasinghe, BE Louie, RW Aye, AS Farivar, E Vallières, and JA Gorden

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Patterns of multidisciplinary tumor board utilization in the management of non-small cell lung cancer The American Thoracic Society San Diego, California, JR Rayburn, Candice L. Wilshire, and See all authors in comments

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Reducing the use of catheters, tubes and imaging after hiatal hernia surgery significantly reduces length of hospital stay Society of American Gastrointestinal and Endoscopic Surgeons Annual Meeting Seattle, Washington, JR Rayburn, Candice L. Wilshire, and See all authors in comments

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Performance status and resource utilization in patients receiving palliative with stage IV advanced non-small cell lung cancer The International Association for the Study of Lung Cancer 19th World Conferenc, J Rayburn, Candice L. Wilshire, Christopher R Gilbert, Roshanthi Weerasignhe, Brian Louie, Ralph W Aye, Alexander S Farivar, Eric Vallieres, and Jed A Gorden

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Multiscale Analysis of Independent Alzheimer's Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus., Ben Readhead, Jean-Vianney Haure-Mirande, Cory C Funk, Matthew A Richards, Paul Shannon, Vahram Haroutunian, Mary Sano, Winnie S Liang, Noam D Beckmann, Nathan D Price, Eric M Reiman, Eric E Schadt, Michelle E Ehrlich, Sam Gandy, and Joel T Dudley

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Correction to: Linkage, whole genome sequence, and biological data implicate variants in RAB10 in Alzheimer's disease resilience., Perry G Ridge, Celeste M Karch, Simon Hsu, Ivan Arano, Craig C Teerlink, Mark T W Ebbert, Josue D Gonzalez Murcia, James M Farnham, Anna R Damato, Mariet Allen, Xue Wang, Oscar Harari, Victoria M Fernandez, Rita Guerreiro, Jose Bras, John Hardy, Ronald Munger, Maria Norton, Celeste Sassi, Andrew Singleton, Steven G Younkin, Dennis W Dickson, Todd E Golde, Nathan D Price, Nilüfer Ertekin-Taner, Carlos Cruchaga, Alison M Goate, Christopher Corcoran, JoAnn Tschanz, Lisa A Cannon-Albright, and John S K Kauwe

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Abstract 15297: High-Density Lipoprotein Function Associates With GlycA, a Novel Inflammation Marker, but Does Not Explain the Association Between GlycA and Incident Cardiovascular Events, Kayla A. Riggs, Parag H. Joshi, Amit Khera, Kavisha Singh, Oludamilola Akinmolayemi, Colby R. Ayers, and Anand Rohatgi

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Genotype Fingerprints Enable Fast and Private Comparison of Genetic Testing Results for Research and Direct-to-Consumer Applications., Max Robinson and Gustavo Glusman

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The Microbiome Stress Project: Toward a Global Meta-Analysis of Environmental Stressors and Their Effects on Microbial Communities., Jennifer D Rocca, Marie Simonin, Joanna R Blaszczak, Jessica G Ernakovich, Sean M Gibbons, Firas S Midani, and Alex D Washburne

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Adverse Events, Patterns of Tumor Lysis Syndrome Prophylaxis and Management, and Dosing Patterns in a Large Cohort of Venetoclax Treated CLL Patients in Community and Academic Settings, Lindsey E. Roeker, Neil Bailey, and See full list of authors in comments

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Extracellular vesicles in DLBCL provide abundant clues to aberrant transcriptional programming and genomic alterations., Sarah C Rutherford, Angela A Fachel, Sheng Li, Seema Sawh, Ashlesha Muley, Jennifer Ishii, Ashish Saxena, Pilar M Dominguez, Eloisi Caldas Lopes, Xabier Agirre, Nyasha Chambwe, Fabian Correa, Yanwen Jiang, Kristy L Richards, Doron Betel, and Rita Shaknovich

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Identification of novel GPR17-agonists by structural bioinformatics and signaling activation., Konda Mani Saravanan, Suresh Palanivel, Olli Yli-Harja, and Meenakshisundaram Kandhavelu

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Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas., Franz X Schaub, Varsha Dhankani, Ashton C Berger, Mihir Trivedi, Anne B Richardson, Reid Shaw, Wei Zhao, Xiaoyang Zhang, Andrea Ventura, Yuexin Liu, Donald E Ayer, Peter J Hurlin, Andrew D Cherniack, Robert N Eisenman, Brady Bernard, Carla Grandori, and Bernard Brady

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A tissue-based draft map of the murine MHC class I immunopeptidome., Heiko Schuster, Wenguang Shao, Tobias Weiss, Patrick G A Pedrioli, Patrick Roth, Michael Weller, David S Campbell, Eric W Deutsch, Robert L Moritz, Oliver Planz, Hans-Georg Rammensee, Ruedi Aebersold, and Etienne Caron

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Centromere protein F (CENPF), a microtubule binding protein, modulates cancer metabolism by regulating pyruvate kinase M2 phosphorylation signaling., Muhammad Shahid, Minyoung Lee, Honit Piplani, Allen M Andres, Bo Zhou, Austin Yeon, Minjung Kim, Hyung L Kim, and Jayoung Kim

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Menthol, a unique urinary volatile compound, is associated with chronic inflammation in interstitial cystitis., Muhammad Shahid, Min Young Lee, Austin Yeon, Eunho Cho, Vikram Sairam, Luis Valdiviez, Sungyong You, and Jayoung Kim

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A Chemical Approach for Profiling Intracellular AKT Signaling Dynamics from Single Cells., Shiqun Shao, Zhonghan Li, Hanjun Cheng, Siwen Wang, Nicole G Perkins, Priyanka Sarkar, Wei Wei, and Min Xue

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The SysteMHC Atlas project., Wenguang Shao, Patrick G A Pedrioli, Witold Wolski, Cristian Scurtescu, Emanuel Schmid, Juan A Vizcaíno, Mathieu Courcelles, Heiko Schuster, Daniel Kowalewski, Fabio Marino, Cecilia S L Arlehamn, Kerrie Vaughan, Bjoern Peters, Alessandro Sette, Tom H M Ottenhoff, Krista E Meijgaarden, Natalie Nieuwenhuizen, Stefan H E Kaufmann, Ralph Schlapbach, John C Castle, Alexey I Nesvizhskii, Morten Nielsen, Eric W Deutsch, David S Campbell, Robert L Moritz, Roman A Zubarev, Anders Jimmy Ytterberg, Anthony W Purcell, Miguel Marcilla, Alberto Paradela, Qi Wang, Catherine E Costello, Nicola Ternette, Peter A van Veelen, Cécile A C M van Els, Albert J R Heck, Gustavo A de Souza, Ludvig M Sollid, Arie Admon, Stefan Stevanovic, Hans-Georg Rammensee, Pierre Thibault, Claude Perreault, Michal Bassani-Sternberg, Ruedi Aebersold, and Etienne Caron

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Radical amino acid mutations persist longer in the absence of sex., Joel Sharbrough, Meagan Luse, Jeffrey L Boore, John M Logsdon, and Maurine Neiman

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Integrated Molecular Characterization of Testicular Germ Cell Tumors., Hui Shen, Juliann Shih, Daniel P Hollern, Linghua Wang, Reanne Bowlby, Satish K Tickoo, Vésteinn Thorsson, Andrew J Mungall, Yulia Newton, Apurva M Hegde, Joshua Armenia, Francisco Sánchez-Vega, John Pluta, Louise C Pyle, Rohit Mehra, Victor E Reuter, Guilherme Godoy, Jeffrey Jones, Carl S Shelley, Darren R Feldman, Daniel O Vidal, Davor Lessel, Tomislav Kulis, Flavio M Cárcano, Kristen M Leraas, Tara M Lichtenberg, Denise Brooks, Andrew D Cherniack, Juok Cho, David I Heiman, Katayoon Kasaian, Minwei Liu, Michael S Noble, Liu Xi, Hailei Zhang, Wanding Zhou, Jean C ZenKlusen, Carolyn M Hutter, Ina Felau, Jiashan Zhang, Nikolaus Schultz, Gad Getz, Matthew Meyerson, Joshua M Stuart, Rehan Akbani, David A Wheeler, Peter W Laird, Katherine L Nathanson, Victoria K Cortessis, and Katherine A Hoadley

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Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding., Leah V Sibener, Ricardo A Fernandes, Elizabeth M Kolawole, Catherine B Carbone, Fan Liu, Darren McAffee, Michael E Birnbaum, Xinbo Yang, Laura F Su, Wong Yu, Shen Dong, Marvin H Gee, Kevin M Jude, Mark M Davis, Jay T Groves, William A Goddard, James R Heath, Brian D Evavold, Ronald D Vale, and K Christopher Garcia

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Examining the paradox of high high-density lipoprotein and elevated cardiovascular risk., Kavisha Singh and Anand Rohatgi

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Robust determination of differential abundance in shotgun proteomics using nonparametric statistics., Patrick Slama, Michael R Hoopmann, Robert L Moritz, and Donald Geman

Pulmonary nodule resection characteristics: experience from lung cancer screening programs in a multi-state, community-based health care network The American Thoracic Society San Diego, California, KM Spiegel, Candice L. Wilshire, and See all authors in comments

Referrals for Lung Cancer Screening: frontline health care professional participation remains low in the community The American Thoracic Society San Diego, California, KM Spiegel, Candice L. Wilshire, and See all authors in comments

POSTER: A QUALITY IMPROVEMENT PROJECT TO INCREASE ADHERENCE TO THE COLLABORATIVE CARE MODEL AT THE SPOKANE TEACHING HEALTH CLINIC, Meghann Sprague, Sadeed Jawad, Christine Prato, and Amy Burns

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Lineage marker synchrony in hematopoietic genealogies refutes the PU.1/GATA1 toggle switch paradigm., Michael K Strasser, Philipp S Hoppe, Dirk Loeffler, Konstantinos D Kokkaliaris, Timm Schroeder, Fabian J Theis, and Carsten Marr

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Plasmodium Parasites Viewed through Proteomics., Kristian E Swearingen and Scott E Lindner

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Regulation of Pathogenic T Helper 17 Cell Differentiation by Steroid Receptor Coactivator-3., Kentaro Tanaka, Gustavo J Martinez, Xiaowei Yan, Weiwen Long, Kenji Ichiyama, Xinxin Chi, Byung-Seok Kim, Joseph M Reynolds, Yeonseok Chung, Shinya Tanaka, Lan Liao, Yoichi Nakanishi, Akihiko Yoshimura, Pan Zheng, Xiaohu Wang, Qiang Tian, Jianming Xu, Bert W O'Malley, and Chen Dong

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Regulation of Pathogenic T Helper 17 Cell Differentiation by Steroid Receptor Coactivator-3., Kentaro Tanaka, Gustavo J Martinez, Xiaowei Yan, Weiwen Long, Kenji Ichiyama, Xinxin Chi, Byung-Seok Kim, Joseph M Reynolds, Yeonseok Chung, Shinya Tanaka, Lan Liao, Yoichi Nakanishi, Akihiko Yoshimura, Pan Zheng, Xiaohu Wang, Qiang Tian, Jianming Xu, Bert W O'Malley, and Chen Dong

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Anatomic Study of Nutrient Foramina of Posterior Axis with Application to C2 Pedicle Screw Placement., Tamir Tawfik, Joe Iwanaga, Emre Yilmaz, Paul Choi, Charlotte Wilson, Emily Simonds, Jared J Marks, Haynes L Harkey, Rod J Oskouian, and R Shane Tubbs

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A Protein Standard That Emulates Homology for the Characterization of Protein Inference Algorithms., Matthew The, Fredrik Edfors, Yasset Perez-Riverol, Samuel H Payne, Michael R Hoopmann, Magnus Palmblad, Björn Forsström, and Lukas Käll

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Taking Systems Medicine to Heart., Kalliopi Trachana, Rhishikesh Bargaje, Gustavo Glusman, Nathan D Price, Sui Huang, and Leroy E Hood

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Gcn4-Mediator Specificity Is Mediated by a Large and Dynamic Fuzzy Protein-Protein Complex., Lisa M Tuttle, Derek Pacheco, Linda Warfield, Jie Luo, Jeff Ranish, Steven Hahn, and Rachel E Klevit

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Can high-volume teams of anesthesiologists and surgeons decrease perioperative costs for pancreatic surgery?, Abhineet Uppal, Brooke Vuong, Ahmed Dehal, Stacey L Stern, Juan Mejia, Roshanthi Weerasinghe, Vandana Kapoor, Evan Ong, Paul D Hansen, and Anton J Bilchik

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Ocean acidification conditions increase resilience of marine diatoms., Jacob J Valenzuela, Adrián López García de Lomana, Allison Lee, E V Armbrust, Mónica V Orellana, and Nitin S Baliga

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Decane-1,2-diol derivatives as potential antitumor agents for the treatment of glioblastoma., Anisha Viswanathan, Anastasia Zhurina, Benedicta Assoah, Aleksi Paakkunainen, Aliyu Musa, Dinesh Kute, Konda Mani Saravanan, Olli Yli-Harja, Nuno R Candeias, and Meenakshisundaram Kandhavelu

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Abstract 12183: SLCO1B1 Genotype-Guided Statin Therapy Lowers LDL Cholesterol in Patients With Statin-Intolerance- A Randomized Controlled Trial, Deepak Voora, Emily Perry, Kavisha Singh, Gloria Trujillo, Nicholas Milazzo, Dillon Savard, Susanne Haga, Michael D. Musty, Yi-Ju Li, and Bruce Peyser

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High-speed Raman-encoded molecular imaging of freshly excised tissue surfaces with topically applied SERRS nanoparticles., Yu Winston Wang, Qian Yang, Soyoung Kang, Matthew A Wall, and Jonathan T C Liu

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Factors predicting attrition in community-based healthcare network lung cancer screening programs The International Association for the Study of Lung Cancer 19th World Conference on Lung Canc, Roshanthi Weerasignhe, Candice L. Wilshire, and See all authors in comments

POSTER: A QI PROJECT TO BRIDGE THE GAP BETWEEN PCP TO PSCYHIATRY REFERRALS, Kourtney Whiteley and Amy Burns

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Multicenter review suggests tunnelled pleural catheter use in antineoplastic therapy-related immun, Candice L. Wilshire

Multicenter review of thymectomy indicated for myasthenia gravis favors a left-sided approach and lower severity class, Candice L. Wilshire, CC Fuller, AF Ghanim, RJ Cerfolio, MW Onaitis, V Joshi, DA Wigle, RW Aye, AS Farivar, E Vallières, and BE Louie

Multicenter review of tunnelled pleural catheter implementation and use in patients with malignant pleural effusions, Candice L. Wilshire, CR Gilbert, JA Akulian, R Asciak, B Bevill, KR Davidson, A Delgado, HJ Lee, JE Lewis, F Maldonado, NJ Pastis, NM Rahman, CB Reddy, and See additional authors in comments

TREATMENT REFRACTORY DEPRESSION, John Wurzel and Amy Burns

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Integrated measurement of intracellular proteins and transcripts in single cells., Alexander M Xu, Qianhe Liu, Kaitlyn L Takata, Sarah Jeoung, Yapeng Su, Igor Antoshechkin, Sisi Chen, Matthew Thomson, and James R Heath

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Recurrent tumor-specific regulation of alternative polyadenylation of cancer-related genes., Zhuyi Xue, René L Warren, Ewan A Gibb, Daniel MacMillan, Johnathan Wong, Readman Chiu, S Austin Hammond, Chen Yang, Ka Ming Nip, Catherine A Ennis, Abigail Hahn, Sheila Reynolds, and Inanc Birol

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Habitual sleep duration and sleep duration variation are independently associated with body mass index., X Xu, M P Conomos, O Manor, J E Rohwer, A T Magis, and J C Lovejoy

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S2 Alar-Iliac Screw Insertion: Technical Note with Pictorial Guide., Emre Yilmaz, Amir Abdul-Jabbar, Tamir Tawfik, Joe Iwanaga, Cameron K Schmidt, Jens R Chapman, Ronen Blecher, R Shane Tubbs, and Rod J Oskouian

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Single vs. dual chamber implantable cardioverter-defibrillators or programming of implantable cardioverter-defibrillators in patients without a bradycardia pacing indication: systematic review and meta-analysis., Emily P Zeitler, Gillian D Sanders, Kavisha Singh, Ruth Ann Greenfield, Anne M Gillis, Bruce L Wilkoff, Jonathan P Piccini, and Sana M Al-Khatib

Submissions from 2017

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New Guidelines for Publication of Manuscripts Describing Development and Application of Targeted Mass Spectrometry Measurements of Peptides and Proteins., Susan Abbatiello, Bradley L Ackermann, Christoph Borchers, Ralph A Bradshaw, Steven A Carr, Robert Chalkley, Meena Choi, Eric Deutsch, Bruno Domon, Andrew N Hoofnagle, Hasmik Keshishian, Eric Kuhn, Daniel C Liebler, Michael MacCoss, Brendan MacLean, D R Mani, Hendrik Neubert, Derek Smith, Olga Vitek, and Lisa Zimmerman