Providence research from Washington locations.

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Submissions from 2020

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Community is the Best Medicine, Ryder Gwinn, James Bowen, and Nancy B. Isenberg

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Number needed to treat with ursodeoxycholic acid therapy to prevent liver transplantation or death in primary biliary cholangitis., Maren H Harms, Rozanne C de Veer, Willem J Lammers, Christophe Corpechot, Douglas Thorburn, Harry L A Janssen, Keith D Lindor, Palak J Trivedi, Gideon M Hirschfield, Albert Pares, Annarosa Floreani, Marlyn J Mayo, Pietro Invernizzi, Pier Maria Battezzati, Frederik Nevens, Cyriel Y Ponsioen, Andrew L Mason, Kris V Kowdley, Bettina E Hansen, Henk R van Buuren, and Adriaan J van der Meer

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Endoscopic transpapillary stenting for the management of acute cholecystitis., Danielle Hayes, Gary Lucas, Andrew Discolo, Bryce French, and Sean Wells

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Is interval appendectomy really needed? A closer look at neoplasm rates in adult patients undergoing interval appendectomy after complicated appendicitis., Danielle Hayes, Shelby Reiter, Ed Hagen, Gary Lucas, Isabelle Chu, Tobias Muñiz, and Ryan Martinez

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Interdisciplinary Profile: An Established Chemist Journeys into Different Disciplines., James R Heath

POSTER: Patient-Focused Clinical Pathway for Inpatient Management of Opioid Use Disorder (OUD), Chris Hellekson, Amy Burns, and See full list of authors in comments

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Integration of time-series meta-omics data reveals how microbial ecosystems respond to disturbance., Malte Herold, Susana Martínez Arbas, Shaman Narayanasamy, Abdul R Sheik, Luise A K Kleine-Borgmann, Laura A Lebrun, Benoît J Kunath, Hugo Roume, Irina Bessarab, Rohan B H Williams, John D Gillece, James M Schupp, Paul S Keim, Christian Jäger, Michael R Hoopmann, Robert L Moritz, Yuzhen Ye, Sujun Li, Haixu Tang, Anna Heintz-Buschart, Patrick May, Emilie E L Muller, Cedric C Laczny, and Paul Wilmes

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Lumenal calcification and microvasculopathy in fetuin-A-deficient mice lead to multiple organ morbidity., Marietta Herrmann, Anne Babler, Irina Moshkova, Felix Gremse, Fabian Kiessling, Ulrike Kusebauch, Valentin Nelea, Rafael Kramann, Robert L Moritz, Marc D McKee, and Willi Jahnen-Dechent

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Improving Exempt Nurse Leader Work-Life Balance: An Innovation Study, Shelly Hicks Cain

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Facebook Live: Dr. Rod Hochman, Providence CEO and Prof. Jim Health Ph.D. discuss the science around Coronavirus., Rod Hochman and Jim Heath

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Engaging an unstably housed population with low-barrier buprenorphine treatment at a syringe services program: Lessons learned from Seattle, Washington., Julia E Hood, Caleb J Banta-Green, Jeffrey S Duchin, Joseph Breuner, Wendy Dell, Brad Finegood, Sara N Glick, Malin Hamblin, Shayla Holcomb, Darla Mosse, Thea Oliphant-Wells, and Mi-Hyun Mia Shim

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Insights from the First Phosphopeptide Challenge of the MS Resource Pillar of the HUPO Human Proteome Project., Michael R Hoopmann, Ulrike Kusebauch, Magnus Palmblad, Nuno Bandeira, David Shteynberg, Lingjie He, Bin Xia, Stoyan H Stoychev, Gilbert S Omenn, Susan T Weintraub, and Robert L Moritz

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Quality and Clinical Care Development in Spine Surgery-Connecting the Dots: An Expanded Clinical Narrative., Sarah Hopkins, Polly Brune, Jens R Chapman, Marc Horton, Rod J Oskouian, Akshal Patel, and Marc D Moisi

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Average Fitness Differences on NK Landscapes., Wim Hordijk, Stuart A Kauffman, and Peter F Stadler

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Building a circular RNA centered gene regulation network associated with cervical squamous cell carcinoma., Wei Hu, Qingqing Li, Xiaoyi He, Ming Gao, Zhanfu Zheng, Yuanlin Ding, Kai Wang, and Yuqing He

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Internal and External Validation of a 90-Day Percentage Erection Fullness Score Model Predicting Potency Recovery Following Robot-assisted Radical Prostatectomy., Linda M Huynh, Douglas Skarecky, Timothy Wilson, Clayon Lau, Christian Wagner, James Porter, Jorn H Witt, and Thomas E Ahlering

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Chapter: Cognitive Neurology, Nancy B. Isenberg

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Tips for Healthy Aging: A Conversation About Dementia with Dr. Nancy Isenberg, Nancy B. Isenberg

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The Petroclinoid Ligament: Its Morphometrics, Relationships, Variations, and Suggestion for New Terminology., Joe Iwanaga, Juan J Altafulla, Santiago Gutierrez, Graham Dupont, Koichi Watanabe, Zachary Litvack, and R Shane Tubbs

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Modulation of Immune Checkpoints by Chemotherapy in Human Colorectal Liver Metastases., Neda Jabbari, Heidi L Kenerson, Christopher Lausted, Xiaowei Yan, Changting Meng, Kevin M Sullivan, Priyanka Baloni, Dani E Bergey, Venu G Pillarisetty, Leroy Hood, Raymond S Yeung, and Qiang Tian

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Staging System for Neuroendocrine Tumors of the Lung Needs to Incorporate Histologic Grade., Anee Sophia Jackson, Adam Rosenthal, Maria Cattoni, Adam J Bograd, Alexander S Farivar, Ralph W Aye, Eric Vallières, and Brian Louie

Primary surgical management of complicated pleural space infections has superior outcomes when compared to intra-pleural fibrinolytic therapy, AS Jackson, Candice L. Wilshire, SC Chang, LC Horslen, JR Rayburn, CC Fuller, AS Farivar, AJ Bograd, RW Aye, BE Louie, E Vallières, CR Gilbert, and JA Gorden

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Comparative lipidomics of 5-Fluorouracil-sensitive and -resistant colorectal cancer cells reveals altered sphingomyelin and ceramide controlled by acid sphingomyelinase (SMPD1)., Jae Hun Jung, Kohei Taniguchi, Hyeong Min Lee, Min Young Lee, Raju Bandu, Kazumasa Komura, Kil Yeon Lee, Yukihiro Akao, and Kwang Pyo Kim

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National Cancer Institute Think-Tank Meeting Report on Proteomic Cartography and Biomarkers at the Single-Cell Level: Interrogation of Premalignant Lesions., Jacob Kagan, Robert L Moritz, Richard Mazurchuk, Je Hyuk Lee, Peter Vasili Kharchenko, Orit Rozenblatt-Rosen, Eytan Ruppin, Fredrik Edfors, Fiona Ginty, Yury Goltsev, James A Wells, John LaCava, Jessica L Riesterer, Ronald N Germain, Tujin Shi, Mark S Chee, Bogdan A Budnik, John R Yates, Brian T Chait, Jeffery R Moffitt, Richard D Smith, and Sudhir Srivastava

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Answering Schrödinger's "What Is Life?", Stuart Kauffman

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Theory of chemical evolution of molecule compositions in the universe, in the Miller-Urey experiment and the mass distribution of interstellar and intergalactic molecules., Stuart A Kauffman, Dávid Péter Jelenfi, and Gábor Vattay

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Theory of chemical evolution of molecule compositions in the universe, in the Miller-Urey experiment and the mass distribution of interstellar and intergalactic molecules., Stuart A Kauffman, Dávid Péter Jelenfi, and Gábor Vattay

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An Exploratory Pilot Study with Plasma Protein Signatures Associated with Response of Patients with Depression to Antidepressant Treatment for 10 Weeks., Eun Young Kim, Hee-Sung Ahn, Min Young Lee, Jiyoung Yu, Jeonghun Yeom, Hwangkyo Jeong, Hophil Min, Hyun Jeong Lee, Kyunggon Kim, and Yong Min Ahn

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Assembly of SNAPc, Bdp1, and TBP on the U6 snRNA gene promoter in Drosophila melanogaster., Mun Kyoung Kim, An Tranvo, Ann Marie Hurlburt, Neha Verma, Phuc Phan, Jie Luo, Jeff Ranish, and William E Stumph

Core transcriptional regulatory circuits in prion diseases., Taek-Kyun Kim, Inyoul Lee, Ji-Hoon Cho, Brenda Canine, Andrew Keller, Nathan D Price, Daehee Hwang, George Carlson, and Leroy Hood

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Cholecystectomy for Biliary Pancreatitis Is Often Not Performed During Index Hospitalization and Is Associated With Worse Outcomes., Divyanshoo R Kohli, Madhav Desai, Kevin F Kennedy, Sravanthi Parasa, and Prateek Sharma

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Plasma levels of soluble ACE2are associated with sex, Metabolic Syndrome, and its biomarkers in a large cohort, pointing to a possible mechanism for increased severity in COVID-19., Sergey A Kornilov, Isabelle Lucas, Kathleen Jade, Chengzhen L Dai, Jennifer C Lovejoy, and Andrew T Magis

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Ineffective esophageal motility is not a contraindication to total fundoplication., Anne-Sophie Laliberte, Brian Louie, Candice L. Wilshire, Alexander S Farivar, Adam J Bograd, and Ralph W Aye

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Patterns of Alcohol Use After Early Liver Transplantation for Alcoholic Hepatitis., Brian P Lee, Gene Y Im, John P Rice, Ann Lazar, Ethan Weinberg, Hyosun Han, Haripriya Maddur, R Mark Ghobrial, George Therapondos, Christine Hsu, Oren K Fix, Sheila Eswaran, Kirti Shetty, Jag Chhatwal, Ozden O Dalgic, Neha Jakhete, Constance Mobley, David W Victor, Neil Mehta, Lisanne Dinges, Mary Rinella, Thomas D Schiano, Michael R Lucey, and Norah Terrault

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Phase 1 study of CWP232291 in patients with relapsed or refractory acute myeloid leukemia and myelodysplastic syndrome., Je-Hwan Lee, Stefan Faderl, John M Pagel, Chul Won Jung, Sung-Soo Yoon, Animesh D Pardanani, Pamela S Becker, Howard Lee, Jeongeun Choi, Kyoungjune Lee, Minkyoung Kim, and Jorge E Cortes

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Epigenome signatures landscaped by histone H3K9me3 are associated with the synaptic dysfunction in Alzheimer's disease., Min Young Lee, Junghee Lee, Seung Jae Hyeon, Hyesun Cho, Yu Jin Hwang, Jong-Yeon Shin, Ann C McKee, Neil W Kowall, Jong-Il Kim, Thor D Stein, Daehee Hwang, and Hoon Ryu

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Characterizing the cancer-associated microbiome with small RNA sequencing data., Wei-Hao Lee, Kai-Pu Chen, Kai Wang, Hsuan-Cheng Huang, and Hsueh-Fen Juan

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Invited Commentary., Eric J Lehr and John Petersen

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Toward Increased Reliability, Transparency, and Accessibility in Cross-linking Mass Spectrometry., Alexander Leitner, Alexandre M J J Bonvin, Christoph H Borchers, Robert J Chalkley, Julia Chamot-Rooke, Colin W Combe, Jürgen Cox, Meng-Qiu Dong, Lutz Fischer, Michael Götze, Fabio C Gozzo, Albert J R Heck, Michael R Hoopmann, Lan Huang, Yasushi Ishihama, Andrew R Jones, Nir Kalisman, Oliver Kohlbacher, Karl Mechtler, Robert L Moritz, Eugen Netz, Petr Novak, Evgeniy Petrotchenko, Andrej Sali, Richard A Scheltema, Carla Schmidt, David Schriemer, Andrea Sinz, Frank Sobott, Florian Stengel, Konstantinos Thalassinos, Henning Urlaub, Rosa Viner, Juan A Vizcaíno, Marc R Wilkins, and Juri Rappsilber

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Longitudinal analysis reveals transition barriers between dominant ecological states in the gut microbiome., Roie Levy, Andrew T Magis, John C Earls, Ohad Manor, Tomasz Wilmanski, Jennifer Lovejoy, Sean M Gibbons, Gilbert S Omenn, Leroy Hood, and Nathan D Price

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Proceedings of the 2019 Santa Fe Bone Symposium: New Concepts in the Care of Osteoporosis and Rare Bone Diseases., E Michael Lewiecki, John P Bilezikian, Risa Kagan, Deborah Krakow, Michael R McClung, Paul D Miller, Eric T Rush, Christopher R Shuhart, Nelson B Watts, and Elaine W Yu

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MEMOTE for standardized genome-scale metabolic model testing., Christian Lieven, Moritz E Beber, Brett G Olivier, Frank T Bergmann, Meric Ataman, Parizad Babaei, Jennifer A Bartell, Lars M Blank, Siddharth Chauhan, Kevin Correia, Christian Diener, Andreas Dräger, Birgitta E Ebert, Janaka N Edirisinghe, José P Faria, Adam M Feist, Georgios Fengos, Ronan M T Fleming, Beatriz García-Jiménez, Vassily Hatzimanikatis, Wout van Helvoirt, Christopher S Henry, Henning Hermjakob, Markus J Herrgård, Ali Kaafarani, Hyun Uk Kim, Zachary King, Steffen Klamt, Edda Klipp, Jasper J Koehorst, Matthias König, Meiyappan Lakshmanan, Dong-Yup Lee, Sang Yup Lee, Sunjae Lee, Nathan E Lewis, Filipe Liu, Hongwu Ma, Daniel Machado, Radhakrishnan Mahadevan, Paulo Maia, Adil Mardinoglu, Gregory L Medlock, Jonathan M Monk, Jens Nielsen, Lars Keld Nielsen, Juan Nogales, Intawat Nookaew, Bernhard O Palsson, Jason A Papin, Kiran R Patil, Mark Poolman, Nathan D Price, Osbaldo Resendis-Antonio, Anne Richelle, Isabel Rocha, Benjamín J Sánchez, Peter J Schaap, Rahuman S Malik Sheriff, Saeed Shoaie, Nikolaus Sonnenschein, Bas Teusink, Paulo Vilaça, Jon Olav Vik, Judith A H Wodke, Joana C Xavier, Qianqian Yuan, Maksim Zakhartsev, and Cheng Zhang

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Publisher Correction: MEMOTE for standardized genome-scale metabolic model testing., Christian Lieven, Moritz E Beber, Brett G Olivier, Frank T Bergmann, Meric Ataman, Parizad Babaei, Jennifer A Bartell, Lars M Blank, Siddharth Chauhan, Kevin Correia, Christian Diener, Andreas Dräger, Birgitta E Ebert, Janaka N Edirisinghe, José P Faria, Adam M Feist, Georgios Fengos, Ronan M T Fleming, Beatriz García-Jiménez, Vassily Hatzimanikatis, Wout van Helvoirt, Christopher S Henry, Henning Hermjakob, Markus J Herrgård, Ali Kaafarani, Hyun Uk Kim, Zachary King, Steffen Klamt, Edda Klipp, Jasper J Koehorst, Matthias König, Meiyappan Lakshmanan, Dong-Yup Lee, Sang Yup Lee, Sunjae Lee, Nathan E Lewis, Filipe Liu, Hongwu Ma, Daniel Machado, Radhakrishnan Mahadevan, Paulo Maia, Adil Mardinoglu, Gregory L Medlock, Jonathan M Monk, Jens Nielsen, Lars Keld Nielsen, Juan Nogales, Intawat Nookaew, Bernhard O Palsson, Jason A Papin, Kiran R Patil, Mark Poolman, Nathan D Price, Osbaldo Resendis-Antonio, Anne Richelle, Isabel Rocha, Benjamín J Sánchez, Peter J Schaap, Rahuman S Malik Sheriff, Saeed Shoaie, Nikolaus Sonnenschein, Bas Teusink, Paulo Vilaça, Jon Olav Vik, Judith A H Wodke, Joana C Xavier, Qianqian Yuan, Maksim Zakhartsev, and Cheng Zhang

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iREAD: a tool for intron retention detection from RNA-seq data., Hong-Dong Li, Cory C Funk, and Nathan D Price

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IsoResolve: Predicting Splice Isoform Functions by Integrating Gene and Isoform-level Features with Domain Adaptation., Hong-Dong Li, Changhuo Yang, Zhimin Zhang, Mengyun Yang, Fang-Xiang Wu, Gilbert S Omenn, and Jianxin Wang

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The power of social media: A call for change in professional perspective., Kira Long

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Selective Translation of Low Abundance and Upregulated Transcripts in Halobacterium salinarum., Adrián López García de Lomana, Ulrike Kusebauch, Arjun V Raman, Min Pan, Serdar Turkarslan, Alan P R Lorenzetti, Robert L Moritz, and Nitin Baliga

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Commentary: Defining low-risk lesions for esophageal preservation informed by resecting the organ., Brian Louie

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Commentary: Toward Minimally Invasive Management of Epiphrenic Diverticula., Brian Louie

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Response to the Comment on "Objective Evidence of Reflux Control After Magnetic Sphincter Augmentation: One Year Results From a Post Approval Study"., Brian Louie, Christy Dunst, and John C Lipham

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A synthesis of bacterial and archaeal phenotypic trait data., Joshua S Madin, Daniel A Nielsen, Maria Brbic, Ross Corkrey, David Danko, Kyle Edwards, Martin K M Engqvist, Noah Fierer, Jemma L Geoghegan, Michael Gillings, Nikos C Kyrpides, Elena Litchman, Christopher E Mason, Lisa Moore, Søren L Nielsen, Ian T Paulsen, Nathan D Price, T B K Reddy, Matthew A Richards, Eduardo P C Rocha, Thomas M Schmidt, Heba Shaaban, Maulik Shukla, Fran Supek, Sasha G Tetu, Sara Vieira-Silva, Alice R Wattam, David A Westfall, and Mark Westoby

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Untargeted longitudinal analysis of a wellness cohort identifies markers of metastatic cancer years prior to diagnosis., Andrew T Magis, Noa Rappaport, Matthew P Conomos, Gilbert S Omenn, Jennifer C Lovejoy, Leroy Hood, and Nathan D Price

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Graph-based exploitation of gene ontology using GOxploreR for scrutinizing biological significance., Kalifa Manjang, Shailesh Tripathi, Olli Yli-Harja, Matthias Dehmer, and Frank Emmert-Streib

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Health and disease markers correlate with gut microbiome composition across thousands of people., Ohad Manor, Chengzhen L Dai, Sergey A Kornilov, Brett Smith, Nathan D Price, Jennifer C Lovejoy, Sean M Gibbons, and Andrew T Magis

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Consensus-Building efforts to identify best tools for screening and assessment for supportive services in oncology., Timothy F Marshall, Catherine M Alfano, Alix G Sleight, Richard P Moser, David S Zucker, Elise L Rice, Julie K Silver, Vishwa S Raj, Jack B Fu, Lynne S Padgett, Kathleen Doyle Lyons, Mary Vining Radomski, Raymond McKenna, and Mackenzi Pergolotti

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Roles of bacteriophages, plasmids and CRISPR immunity in microbial community dynamics revealed using time-series integrated meta-omics., Susana Martínez Arbas, Shaman Narayanasamy, Malte Herold, Laura A Lebrun, Michael R Hoopmann, Sujun Li, Tony J Lam, Benoît J Kunath, Nathan D Hicks, Cindy M Liu, Lance B Price, Cedric C Laczny, John D Gillece, James M Schupp, Paul S Keim, Robert L Moritz, Karoline Faust, Haixu Tang, Yuzhen Ye, Alexander Skupin, Patrick May, Emilie E L Muller, and Paul Wilmes

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A Structural Model of the Endogenous Human BAF Complex Informs Disease Mechanisms., Nazar Mashtalir, Hiroshi Suzuki, Daniel P Farrell, Akshay Sankar, Jie Luo, Martin Filipovski, Andrew R D'Avino, Roodolph St Pierre, Alfredo M Valencia, Takashi Onikubo, Robert G Roeder, Yan Han, Yuan He, Jeffrey A Ranish, Frank DiMaio, Thomas Walz, and Cigall Kadoch

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Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality., Fred D Mast, Arti T Navare, Almer M van der Sloot, Jasmin Coulombe-Huntington, Michael P Rout, Nitin Baliga, Alexis Kaushansky, Brian T Chait, Alan Aderem, Charles M Rice, Andrej Sali, Mike Tyers, and John D Aitchison

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Presentation 1209-083: Soluble FMS-Like Tyrosine Kinase-1 (Sflt-1) is Associated with Subclinical and Clinical ASCVD: The Dallas Heart Study, Rina Mauricio, Kavisha Singh, Monika Sanghavi, Colby Ayers, Anand Rohatgi, Wanpen Vongpatanasin, James de Lemos, and Amit Khera

Ineffective esophageal motility is not a contraindication to total fundoplication in appropriately selected patients The Annual Meeting of The Society of American Gastrointestinal and Endoscopic Surgeons Cleveland, Ohio, BM McCall, Candice L. Wilshire, and See all authors in comments

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Author Correction: New paradigms for understanding and step changes in treating active and chronic, persistent apicomplexan infections., Martin McPhillie, Ying Zhou, Kamal El Bissati, Jitender Dubey, Hernan Lorenzi, Michael Capper, Amanda K Lukens, Mark Hickman, Stephen Muench, Shiv Kumar Verma, Christopher R Weber, Kelsey Wheeler, James Gordon, Justin Sanders, Hong Moulton, Kai Wang, Taek-Kyun Kim, Yuqing He, Tatiana Santos, Stuart Woods, Patty Lee, David Donkin, Eric Kim, Laura Fraczek, Joseph Lykins, Farida Esaa, Fatima Alibana-Clouser, Sarah Dovgin, Louis Weiss, Gael Brasseur, Dyann Wirth, Michael Kent, Leroy Hood, Brigitte Meunieur, Craig W Roberts, S Samar Hasnain, Svetlana V Antonyuk, Colin Fishwick, and Rima McLeod

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Chronic elevation of plasma vascular endothelial growth factor-A (VEGF-A) is associated with a history of blast exposure., James S Meabon, David G Cook, Mayumi Yagi, Garth E Terry, Donna J Cross, Mark Muzi, Kathleen F Pagulayan, Aric F Logsdon, Abigail G Schindler, Vikas Ghai, Kai Wang, Shannon Fallen, Yong Zhou, Taek-Kyun Kim, Inyoul Lee, William A Banks, Erik S Carlson, Cynthia Mayer, Rebecca C Hendrickson, Murray A Raskind, Desiree A Marshall, Daniel P Perl, C Dirk Keene, and Elaine R Peskind

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Poor prognostic factors in predicting abatacept response in a phase III randomized controlled trial in psoriatic arthritis., Philip J Mease, Iain B McInnes, Vibeke Strand, Oliver FitzGerald, Harris A Ahmad, Yedid Elbez, and Subhashis Banerjee

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Return to work and functional status shows prolonged impact following management of a complicated pleural space infection The American Thoracic Society Philadelphia, Pennsylvania, AM Meggyesy, Candice L. Wilshire, and See all authors in comments

Stage IV non-small cell lung cancer outpatient palliative care referral results in longer survival but no decrease in hospital resource utilization in the last 30 days of life The American Thoracic Society Philadelphia, Pennsy, AM Meggyesy, Candice L. Wilshire, and See all authors in comments

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DIALib-QC an assessment tool for spectral libraries in data-independent acquisition proteomics., Mukul K Midha, David S Campbell, Charu Kapil, Ulrike Kusebauch, Michael R Hoopmann, Samuel L Bader, and Robert L Moritz

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A comprehensive spectral assay library to quantify the Escherichia coli proteome by DIA/SWATH-MS., Mukul K Midha, Ulrike Kusebauch, David Shteynberg, Charu Kapil, Samuel L Bader, Panga Jaipal Reddy, David S Campbell, Nitin Baliga, and Robert L Moritz

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A Review of the Scientific Rigor, Reproducibility, and Transparency Studies Conducted by the ABRF Research Groups., Sheenah M Mische, Nancy C Fisher, Susan M Meyn, Katia Sol Church, Rebecca L Hegstad-Davies, Frances Weis-Garcia, Marie Adams, John M Ashton, Kym M Delventhal, Julie A Dragon, Laura Holmes, Pratik Jagtap, Christopher E Mason, Magnus Palmblad, Brian C Searle, Christoph W Turck, and Kevin L Knudtson

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Comment on: "Active Surveillance Versus Immediate Surgery in Clinically Complete Responders After Neoadjuvant Chemoradiotherapy for Esophageal Cancer"., Daniela Molena, Brian Louie, and Steven R Demeester

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Simplified care-pathway selection for nonspecialist practice: the GLOBAL Primary Biliary Cholangitis Study Group Age, Bilirubin, Alkaline phosphatase risk assessment tool., Carla F Murillo Perez, Aliya Gulamhusein, Marco Carbone, Palak J Trivedi, Adriaan J van der Meer, Christophe Corpechot, Pier Maria Battezzati, Willem J Lammers, Nora Cazzagon, Annarosa Floreani, Albert Parés, Frederik Nevens, Ana Lleo, Marlyn J Mayo, Kris V Kowdley, Cyriel Y Ponsioen, George N Dalekos, Nikolaos K Gatselis, Douglas Thorburn, Andrew L Mason, Harry Janssen, Xavier Verhelst, Tony Bruns, Keith D Lindor, Olivier Chazouillères, Pietro Invernizzi, Bettina E Hansen, Gideon M Hirschfield, and GLOBAL PBC Study Group

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Design and synthesis of novel quinic acid derivatives:, Akshaya Murugesan, Suvi Holmstedt, Kenna C Brown, Alisa Koivuporras, Ana S Macedo, Nga Nguyen, Pedro Fonte, Patrícia Rijo, Olli Yli-Harja, Nuno R Candeias, and Meenakshisundaram Kandhavelu

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Transcriptomic analysis of glioblastoma multiforme providing new insights into GPR17 signaling communication., Gnanavel Mutharasu, Akshaya Murugesan, Saravanan Konda Mani, Olli Yli-Harja, and Meenakshisundaram Kandhavelu

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Effect of Pembrolizumab Plus Neoadjuvant Chemotherapy on Pathologic Complete Response in Women With Early-Stage Breast Cancer: An Analysis of the Ongoing Phase 2 Adaptively Randomized I-SPY2 Trial., Rita Nanda, Minetta C Liu, Christina Yau, Rebecca Shatsky, Lajos Pusztai, Anne Wallace, A Jo Chien, Andres Forero-Torres, Erin D Ellis, Heather Han, Amy Clark, Kathy Albain, Judy C Boughey, Nora T Jaskowiak, Anthony Elias, Claudine Isaacs, Kathleen Kemmer, Teresa Helsten, Melanie Majure, Erica Stringer-Reasor, Catherine Parker, Marie C Lee, Tufia Haddad, Ronald N Cohen, Smita Asare, Amy Wilson, Gillian L Hirst, Ruby Singhrao, Katherine Steeg, Adam Asare, Jeffrey B Matthews, Scott Berry, Ashish Sanil, Richard Schwab, W Fraser Symmans, Laura van 't Veer, Douglas Yee, Angela DeMichele, Nola M Hylton, Michelle Melisko, Jane Perlmutter, Hope S Rugo, Donald A Berry, and Laura J Esserman

POSTER: Optimizing Transgender Identification in Epic at the STHC Family Medicine Clinic., Cedar Neary, Sarah Wilhelm, and Amy Burns

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Efficacy of tofacitinib in reducing pain in patients with rheumatoid arthritis, psoriatic arthritis or ankylosing spondylitis., Alexis Ogdie, Kurt de Vlam, Iain B McInnes, Philip J Mease, Philip Baer, Tatjana Lukic, David Gruben, Kenneth Kwok, Cunshan Wang, Ming-Ann Hsu, and Anna Maniccia

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Pilot Study of an Integrated Smartphone and Breathalyzer Contingency Management Intervention for Alcohol Use., Oladunni Oluwoye, Hailey Reneau, Jalene Herron, Karl C Alcover, Sterling M McPherson, John Roll, and Michael G McDonell

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Research on the Human Proteome Reaches a Major Milestone: >90% of Predicted Human Proteins Now Credibly Detected, According to the HUPO Human Proteome Project., Gilbert S Omenn, Lydie Lane, Christopher M Overall, Ileana M Cristea, Fernando J Corrales, Cecilia Lindskog, Young-Ki Paik, Jennifer E Van Eyk, Siqi Liu, Stephen R Pennington, Michael P Snyder, Mark S Baker, Nuno Bandeira, Ruedi Aebersold, Robert L Moritz, and Eric W Deutsch

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Effect of Secukinumab on the Different GRAPPA-OMERACT Core Domains in Psoriatic Arthritis: A Pooled Analysis of 2049 Patients., Ana-Maria Orbai, Iain B McInnes, Laura C Coates, M Elaine Husni, Dafna D Gladman, Laure Gossec, Luminita Pricop, Olivier Chambenoit, Xiangyi Meng, and Philip Mease

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Treatment selection in patients with relapsed or refractory follicular lymphoma., John M Pagel

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Refining the management of relapsed or refractory follicular lymphoma., John M Pagel, John M Burke, and Lori A Leslie

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Refining the management of relapsed or refractory follicular lymphoma: case scenarios., John M Pagel, John M Burke, and Lori A Leslie

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Antiproliferative and apoptotic effects of indole derivative, N-(2-hydroxy-5-nitrophenyl (4'-methylphenyl) methyl) indoline in breast cancer cells., Suresh Palanivel, Akshaya Murugesan, Kumar Subramanian, Olli Yli-Harja, and Meenakshisundaram Kandhavelu

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Inflammation resolution: a dual-pronged approach to averting cytokine storms in COVID-19?, Dipak Panigrahy, Molly M Gilligan, Sui Huang, Allison Gartung, Irene Cortés-Puch, Patricia J Sime, Richard P Phipps, Charles N Serhan, and Bruce D Hammock

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Deep phenotyping during pregnancy for predictive and preventive medicine., Alison G Paquette, Leroy Hood, Nathan D Price, and Yoel Sadovsky

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Prevalence of Gastrointestinal Symptoms and Fecal Viral Shedding in Patients With Coronavirus Disease 2019: A Systematic Review and Meta-analysis., Sravanthi Parasa, Madhav Desai, Viveksandeep Thoguluva Chandrasekar, Harsh K Patel, Kevin F Kennedy, Thomas Roesch, Marco Spadaccini, Matteo Colombo, Roberto Gabbiadini, Everson L A Artifon, Alessandro Repici, and Prateek Sharma

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Global Impact of the COVID-19 Pandemic on Endoscopy: An International Survey of 252 Centers from 55 Countries., Sravanthi Parasa, Nageshwar Reddy, Douglas O Faigel, Alessandro Repici, Fabian Emura, and Prateek Sharma

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Pre-existing immunity to influenza virus hemagglutinin stalk might drive selection for antibody-escape mutant viruses in a human challenge model., Jae-Keun Park, Yongli Xiao, Mitchell D Ramuta, Luz Angela Rosas, Sharon Fong, Alexis M Matthews, Ashley D Freeman, Monica A Gouzoulis, Natalia A Batchenkova, Xingdong Yang, Kelsey Scherler, Li Qi, Susan Reed, Rani Athota, Lindsay Czajkowski, Alison Han, David M Morens, Kathie-Anne Walters, Matthew J Memoli, John C Kash, and Jeffery K Taubenberger

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Investigating the Effects of Brainstem Neuronal Adaptation on Cardiovascular Homeostasis., James H Park, Jonathan Gorky, Babatunde Ogunnaike, Rajanikanth Vadigepalli, and James S Schwaber

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A Phase 2, Open-Label, Multicenter Study of Tazemetostat in Combination with Rituximab for the Treatment of Relapsed or Refractory Follicular Lymphoma, Krish Patel, Neil Bailey, and John M Pagel

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Real World Observational Study Using Clonoseq® Next Generation Sequencing in Hematologic Malignancies: The 'Watch' Registry, Krish Patel, Neil Bailey, John M Pagel, and See all authors in comments

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Employed Mothers’ Satisfaction with the Breastfeeding Provisions in the Patient Protection and Affordable Care Act, Rebecca Penders

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Intricate Genetic Programs Controlling Dormancy in Mycobacterium tuberculosis., Eliza Jr Peterson, Abrar A Abidi, Mario L Arrieta-Ortiz, Boris Aguilar, James T Yurkovich, Amardeep Kaur, Min Pan, Vivek Srinivas, Ilya Shmulevich, and Nitin Baliga

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Causal mutations from adaptive laboratory evolution are outlined by multiple scales of genome annotations and condition-specificity., Patrick V Phaneuf, James T Yurkovich, David Heckmann, Muyao Wu, Troy E Sandberg, Zachary A King, Justin Tan, Bernhard O Palsson, and Adam M Feist

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Ageotypes: Distinct Biomolecular Trajectories in Human Aging., Brian D. Piening, Jennifer Lovejoy, and John C Earls

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Acquiring and Analyzing Data Independent Acquisition Proteomics Experiments without Spectrum Libraries., Lindsay K Pino, Seth C Just, Michael J MacCoss, and Brian C Searle

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Absence of full-length dystrophin impairs normal maturation and contraction of cardiomyocytes derived from human-induced pluripotent stem cells., J Manuel Pioner, Xuan Guan, Jordan M Klaiman, Alice W Racca, Lil Pabon, Veronica Muskheli, Jesse Macadangdang, Cecilia Ferrantini, Michael R Hoopmann, Robert L Moritz, Deok-Ho Kim, Chiara Tesi, Corrado Poggesi, Charles E Murry, Martin K Childers, David L Mack, and Michael Regnier

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Decision Matrix-Guided Treatment of Infected Hip Resurfacing., James W. Pritchett

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AKI and Hypercalcemia in a Patient with Weakness and Fatigue., Cheyenne Rahimi, Mathias Stroemel, and Nicole K Andeen

POSTER: Improving Metabolic Monitoring Guideline Adherence in Psychiatry Residency Outpatient Clinic., Shane Rall, Amy Burns, and Lucas Salg

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Birds of a Feather? Genetic Counseling, Genetic Testing, and Humanism., Robert Resta