Providence research from Washington locations.

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Submissions from 2020

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Antiproliferative and apoptotic effects of indole derivative, N-(2-hydroxy-5-nitrophenyl (4'-methylphenyl) methyl) indoline in breast cancer cells., Suresh Palanivel, Akshaya Murugesan, Kumar Subramanian, Olli Yli-Harja, and Meenakshisundaram Kandhavelu

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Inflammation resolution: a dual-pronged approach to averting cytokine storms in COVID-19?, Dipak Panigrahy, Molly M Gilligan, Sui Huang, Allison Gartung, Irene Cortés-Puch, Patricia J Sime, Richard P Phipps, Charles N Serhan, and Bruce D Hammock

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Deep phenotyping during pregnancy for predictive and preventive medicine., Alison G Paquette, Leroy Hood, Nathan D Price, and Yoel Sadovsky

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Prevalence of Gastrointestinal Symptoms and Fecal Viral Shedding in Patients With Coronavirus Disease 2019: A Systematic Review and Meta-analysis., Sravanthi Parasa, Madhav Desai, Viveksandeep Thoguluva Chandrasekar, Harsh K Patel, Kevin F Kennedy, Thomas Roesch, Marco Spadaccini, Matteo Colombo, Roberto Gabbiadini, Everson L A Artifon, Alessandro Repici, and Prateek Sharma

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Global Impact of the COVID-19 Pandemic on Endoscopy: An International Survey of 252 Centers from 55 Countries., Sravanthi Parasa, Nageshwar Reddy, Douglas O Faigel, Alessandro Repici, Fabian Emura, and Prateek Sharma

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Pre-existing immunity to influenza virus hemagglutinin stalk might drive selection for antibody-escape mutant viruses in a human challenge model., Jae-Keun Park, Yongli Xiao, Mitchell D Ramuta, Luz Angela Rosas, Sharon Fong, Alexis M Matthews, Ashley D Freeman, Monica A Gouzoulis, Natalia A Batchenkova, Xingdong Yang, Kelsey Scherler, Li Qi, Susan Reed, Rani Athota, Lindsay Czajkowski, Alison Han, David M Morens, Kathie-Anne Walters, Matthew J Memoli, John C Kash, and Jeffery K Taubenberger

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Investigating the Effects of Brainstem Neuronal Adaptation on Cardiovascular Homeostasis., James H Park, Jonathan Gorky, Babatunde Ogunnaike, Rajanikanth Vadigepalli, and James S Schwaber

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A Phase 2, Open-Label, Multicenter Study of Tazemetostat in Combination with Rituximab for the Treatment of Relapsed or Refractory Follicular Lymphoma, Krish Patel, Neil Bailey, and John M Pagel

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Real World Observational Study Using Clonoseq® Next Generation Sequencing in Hematologic Malignancies: The 'Watch' Registry, Krish Patel, Neil Bailey, John M Pagel, and See all authors in comments

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Employed Mothers’ Satisfaction with the Breastfeeding Provisions in the Patient Protection and Affordable Care Act, Rebecca Penders

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Intricate Genetic Programs Controlling Dormancy in Mycobacterium tuberculosis., Eliza Jr Peterson, Abrar A Abidi, Mario L Arrieta-Ortiz, Boris Aguilar, James T Yurkovich, Amardeep Kaur, Min Pan, Vivek Srinivas, Ilya Shmulevich, and Nitin Baliga

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Causal mutations from adaptive laboratory evolution are outlined by multiple scales of genome annotations and condition-specificity., Patrick V Phaneuf, James T Yurkovich, David Heckmann, Muyao Wu, Troy E Sandberg, Zachary A King, Justin Tan, Bernhard O Palsson, and Adam M Feist

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Ageotypes: Distinct Biomolecular Trajectories in Human Aging., Brian D. Piening, Jennifer Lovejoy, and John C Earls

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Acquiring and Analyzing Data Independent Acquisition Proteomics Experiments without Spectrum Libraries., Lindsay K Pino, Seth C Just, Michael J MacCoss, and Brian C Searle

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Absence of full-length dystrophin impairs normal maturation and contraction of cardiomyocytes derived from human-induced pluripotent stem cells., J Manuel Pioner, Xuan Guan, Jordan M Klaiman, Alice W Racca, Lil Pabon, Veronica Muskheli, Jesse Macadangdang, Cecilia Ferrantini, Michael R Hoopmann, Robert L Moritz, Deok-Ho Kim, Chiara Tesi, Corrado Poggesi, Charles E Murry, Martin K Childers, David L Mack, and Michael Regnier

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Decision Matrix-Guided Treatment of Infected Hip Resurfacing., James W. Pritchett

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AKI and Hypercalcemia in a Patient with Weakness and Fatigue., Cheyenne Rahimi, Mathias Stroemel, and Nicole K Andeen

POSTER: Improving Metabolic Monitoring Guideline Adherence in Psychiatry Residency Outpatient Clinic., Shane Rall, Amy Burns, and Lucas Salg

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Birds of a Feather? Genetic Counseling, Genetic Testing, and Humanism., Robert Resta

Comparison of echocardiographic outcomes following transcatheter aortic valve replacement with Edwards S3 23mm versus Medtronic Evolut 26mm valves, Michael Ring, Ruyun Jin, Rollie Parrish, Brydan Curtis, Matthew Forrester, Branden Reynolds, and Sameer Gafoor

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Gemogenovatucel-T (Vigil) immunotherapy as maintenance in frontline stage III/IV ovarian cancer (VITAL): a randomised, double-blind, placebo-controlled, phase 2b trial., Rodney P Rocconi, Elizabeth A Grosen, Sharad A Ghamande, John K Chan, Minal A Barve, Jonathan Oh, Devansu Tewari, Peter C Morris, Erin E Stevens, Justin N Bottsford-Miller, Min Tang, Phylicia Aaron, Laura Stanbery, Staci Horvath, Gladice Wallraven, Ernest Bognar, Luisa Manning, John Nemunaitis, David Shanahan, Brian M Slomovitz, Thomas J Herzog, Bradley J Monk, and Robert L Coleman

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P0516 (S1638). - An Unexpected Cause of Colitis in a Cardiac Transplant Patient, Medora D. Rodrigues, Michele Rooney, Deirdre M Mooney, Nishant Puri, and Steve Serrao

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P0357 (S1601). - Malignant Melanoma of the Gallbladder Masquerading as Cholangitis and Cholecystitis, Medora Rodrigues, Sanjay Logani, Juan Mejia, Wichit Srikureja, and Nishant Puri

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Retrospective multicenter study on endoscopic treatment of upper gastrointestinal postsurgical leaks., Eduardo Rodrigues-Pinto, Pedro Pereira, Bernardo Sousa-Pinto, Hany Shehab, Rolando Pinho, Michael C Larsen, Shayan Irani, Richard A Kozarek, Antonio Capogreco, Alessandro Repici, Ealaf Shemmeri, Brian Louie, Pawel Rogalski, Andrzej Baniukiewicz, Andrzej Dabrowski, João Correia de Sousa, Silvia Barrias, Yervant Ichkhanian, Vivek Kumbhari, Mouen A Khashab, Nicole Bowers, Allison R Schulman, and Guilherme Macedo

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Worldwide Examination of Patients with CLL Hospitalized for COVID-19, Lindsey E. Roeker, Neil Bailey, and See full list of authors in comments

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Emergence of Organisms., Andrea Roli and Stuart A Kauffman

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A small sustained increase in NOD1 abundance promotes ligand-independent inflammatory and oncogene transcriptional responses., Leah M Rommereim, Ajay Suresh Akhade, Bhaskar Dutta, Carolyn Hutcheon, Nicolas W Lounsbury, Clifford C Rostomily, Ram Savan, Iain D C Fraser, Ronald N Germain, and Naeha Subramanian

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Composition of Caenorhabditis elegans extracellular vesicles suggests roles in metabolism, immunity, and aging., Joshua C Russell, Taek-Kyun Kim, Ayush Noori, Gennifer E Merrihew, Julia E Robbins, Alexandra Golubeva, Kai Wang, Michael J MacCoss, and Matt Kaeberlein

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Modeling the Hepatology Workforce in the United States: A Predicted Critical Shortage., Mark W Russo, Oren K Fix, Ayman A Koteish, Katie Duggan, Marcia Ditmyer, Michael Fuchs, Raymond T Chung, and Gautham Reddy

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Society for Immunotherapy of Cancer clinical and biomarkers data sharing resource document: Volume I-conceptual challenges., Sergio Rutella, Michael A Cannarile, Sacha Gnjatic, Bruno Gomes, Justin Guinney, Vaios Karanikas, Mohan Karkada, John M Kirkwood, Beatrix Kotlan, Giuseppe V Masucci, Els Meeusen, Anne Monette, Aung Naing, Vésteinn Thorsson, Nicholas Tschernia, Ena Wang, Daniel K Wells, Timothy L Wyant, and Alessandra Cesano

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Advancing human health in the decade ahead: pregnancy as a key window for discovery: A Burroughs Wellcome Fund Pregnancy Think Tank., Yoel Sadovsky, Sam Mesiano, Graham J Burton, Michelle Lampl, Jeffrey C Murray, Rachel M Freathy, Anita Mahadevan-Jansen, Ashley Moffett, Nathan D Price, Paul H Wise, Derek E Wildman, Ralph Snyderman, Nigel Paneth, John Anthony Capra, Marcelo A Nobrega, Yaacov Barak, and Louis J Muglia

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Defining the proteolytic landscape during enterovirus infection., Mohsan Saeed, Sebastian Kapell, Nicholas T Hertz, Xianfang Wu, Kierstin Bell, Alison W Ashbrook, Milica Tesic Mark, Henry A Zebroski, Maxwell L Neal, Malin Flodström-Tullberg, Margaret R MacDonald, John D Aitchison, Henrik Molina, and Charles M Rice

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Semiautomated Glasgow-Blatchford Bleeding Score helps direct bed placement for patients with upper gastrointestinal bleeding., Drew B Schembre, Robson E Ely, Janice M Connolly, Kunjali T Padhya, Rohit Sharda, and John J Brandabur

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Generating high quality libraries for DIA MS with empirically corrected peptide predictions., Brian C Searle, Kristian E Swearingen, Christopher A Barnes, Tobias Schmidt, Siegfried Gessulat, Bernhard Küster, and Mathias Wilhelm

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The Influence of Surgical Intervention and Sagittal Alignment on Frailty in Adult Cervical Deformity., Frank A Segreto, Peter Gust Passias, Avery E Brown, Samantha R Horn, Cole A Bortz, Katherine E Pierce, Haddy Alas, Virginie Lafage, Renaud Lafage, Justin S Smith, Breton G Line, Bassel G Diebo, Michael P Kelly, Gregory M Mundis, Themistocles S Protopsaltis, Alex Soroceanu, Han Jo Kim, Eric O Klineberg, Douglas C Burton, Robert A Hart, Frank J Schwab, Shay Bess, Christopher I Shaffrey, and Christopher P Ames

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Serum-borne lipids amplify TLR-activated inflammatory responses., Naveen Sharma, Ajay Suresh Akhade, Sana Ismaeel, and Ayub Qadri

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Developing Quality Metrics For Upper Endoscopy., Prateek Sharma, Sravanthi Parasa, and Nicholas Shaheen

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Use of a report card to evaluate outcomes of achalasia surgery: beyond the Eckardt score., Ealaf Shemmeri, Ralph W Aye, Alexander S Farivar, Adam J Bograd, and Brian E Louie

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Circulating MicroRNAs and Extracellular Vesicle-Containing MicroRNAs as Response Biomarkers of Anti-programmed Cell Death Protein 1 or Programmed Death-Ligand 1 Therapy in NSCLC., Takehito Shukuya, Vikas Ghai, Joseph M Amann, Tamio Okimoto, Konstantin Shilo, Taek-Kyun Kim, Kai Wang, and David P Carbone

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Current Status and Future Prospects of Genome-Scale Metabolic Modeling to Optimize the Use of Mesenchymal Stem Cells in Regenerative Medicine., Þóra Sigmarsdóttir, Sarah McGarrity, Óttar Rolfsson, James T Yurkovich, and Ólafur E Sigurjónsson

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Discovery of a new ligament of the lumbar spine: the midline interlaminar ligament., Emily Simonds, Joe Iwanaga, Basem Ishak, Miguel Angel Reina, Rod J Oskouian, and R Shane Tubbs

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Using Simulation to Assess Cardiology Fellow Performance of Transthoracic Echocardiography: Lessons for Training in the COVID-19 Pandemic., Kavisha Singh, Alvin Chandra, Katy Lonergan, and Anish Bhatt

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Associations Between High-Density Lipoprotein Particles and Ischemic Events by Vascular Domain, Sex, and Ethnicity: A Pooled Cohort Analysis., Kavisha Singh, Alvin Chandra, Thomas Sperry, Parag H Joshi, Amit Khera, Salim S Virani, Christie M Ballantyne, James D Otvos, Robin P F Dullaart, Eke G Gruppen, Margery A Connelly, Colby R Ayers, and Anand Rohatgi

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Presentation 1375-288: When a Pulmonary Embolism is more than meets the eye: Initial Presentation of Patent Ductus Arteriosus in an Adult, Kavisha Singh, Amit Khera, and Michael Luna

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Abstract 14090: Multiparity is Associated With Aortic Pathology in Women From the Dallas Heart Study, Kavisha Singh, Rina Mauricio, Wanpen Vongpatanasin, Katy Lonergan, Monika Sanghavi, Amit Khera, James A De Lemos, Colby Ayers, and Parag H. Joshi

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Behavior-related gene regulatory networks: A new level of organization in the brain., Saurabh Sinha, Beryl M Jones, Ian M Traniello, Syed A Bukhari, Marc S Halfon, Hans A Hofmann, Sui Huang, Paul S Katz, Jason Keagy, Vincent J Lynch, Marla B Sokolowski, Lisa J Stubbs, Shayan Tabe-Bordbar, Mariana F Wolfner, and Gene E Robinson

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The Cancer Rehabilitation Medicine Metrics Consortium: A Path to Enhanced, Multi-Site Outcome Assessment to Enhance Care and Demonstrate Value., Sean R Smith, Mary Vargo, David S Zucker, Maryanne Henderson, Samman Shahpar, Eric M Wisotzky, Christian Custodio, Jeffrey Basford, Gina Jay, Lynn Gerber, and Andrea Cheville

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Surgical Management of Non-Small Cell Lung Cancer Invading the Fissure: Less Is More?, Shane P Smith, Adam J Bograd, Gal Levy, Shu-Ching Chang, Alexander S Farivar, Ralph W Aye, Brian Louie, and Eric Vallieres

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PerSort Facilitates Characterization and Elimination of Persister Subpopulation in Mycobacteria., Vivek Srinivas, Mario L Arrieta-Ortiz, Amardeep Kaur, Eliza Jr Peterson, and Nitin Baliga

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Dynamics of a birth-death process based on combinatorial innovation., Mike Steel, Wim Hordijk, and Stuart A Kauffman

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Multiomic Immunophenotyping of COVID-19 Patients Reveals Early Infection Trajectories., Yapeng Su, Daniel Chen, Christopher Lausted, Dan Yuan, Jongchan Choi, Cheng Dai, Valentin Voillet, Kelsey Scherler, Pamela Troisch, Venkata R Duvvuri, Priyanka Baloni, Guangrong Qin, Brett Smith, Sergey Kornilov, Clifford Rostomily, Alex Xu, Jing Li, Shen Dong, Alissa Rothchild, Jing Zhou, Kim Murray, Rick Edmark, Sunga Hong, Lesley Jones, Yong Zhou, Ryan Roper, Sean Mackay, D Shane O'Mahony, Christopher Dale, Julie A Wallick, Heather A Algren, Zager A Michael, Andrew T Magis, Wei Wei, Nathan D Price, Sui Huang, Naeha Subramanian, Kai Wang, Jennifer Hadlock, Leroy Hood, Alan Aderem, Jeffrey A Bluestone, Lewis L Lanier, Phil Greenberg, Raphael Gottardo, Mark M Davis, Jason D Goldman, James R Heath, and ISB-Swedish COVID19 Biobanking Unit

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Multi-omics resolves a sharp disease-state shift between mild and moderate COVID-19, Yapeng Su, Daniel Chen, Dan Yuan, Christopher Lausted, Jongchan Choi, Chengzhen L Dai, Valentin Voillet, Venkata R Duvvuri, Kelsey Scherler, Pamela Troisch, Priyanka Baloni, Guangrong Qin, Brett Smith, Sergey A Kornilov, Clifford Rostomily, Alex Xu, Jing Li, Shen Dong, Alissa Rothchild, Jing Zhou, Kim Murray, Rick Edmark, Sunga Hong, John Heath, John Earls, Rongyu Zhang, Jingyi Xie, Sarah Li, Ryan Roper, Lesley Jones, Yong Zhou, Lee Rowen, Rachel Liu, Sean Mackay, D Shane O'Mahony, chris dale, Julie A Wallick, Heather A Algren, Zager A. Michael, ISB-Swedish COVID19 Biobanking Unit, Wei Wei, Nathan D Price, Sui Huang, Naeha Subramanian, Kai Wang, Andrew T Magis, Jennifer Hadlock, Leroy Hood, Alan Aderem, Jeffrey A. Bluestone, Lewis L. Lanier, Philip D. Greenberg, Raphael Gottardo, Mark M. Davis, Jason D Goldman, and James R. Heath

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Multi-omic single-cell snapshots reveal multiple independent trajectories to drug tolerance in a melanoma cell line., Yapeng Su, Melissa E Ko, Hanjun Cheng, Ronghui Zhu, Min Xue, Jessica Wang, Jihoon W Lee, Luke Frankiw, Alexander Xu, Stephanie Wong, Lidia Robert, Kaitlyn Takata, Dan Yuan, Yue Lu, Sui Huang, Antoni Ribas, Raphael Levine, Garry P Nolan, Wei Wei, Sylvia K Plevritis, Guideng Li, David Baltimore, and James R Heath

POSTER: CLOSE ALL THE CRACKS! TRANSITIONS OF CARE IN THE OUTPATIENT SETTING, Brian Swett, Christine Prato, and Amy Burns

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Active learning narrows achievement gaps for underrepresented students in undergraduate science, technology, engineering, and math., Elli J Theobald, Mariah J Hill, Elisa Tran, Sweta Agrawal, E Nicole Arroyo, Shawn Behling, Nyasha Chambwe, Dianne Laboy Cintrón, Jacob D Cooper, Gideon Dunster, Jared A Grummer, Kelly Hennessey, Jennifer Hsiao, Nicole Iranon, Leonard Jones, Hannah Jordt, Marlowe Keller, Melissa E Lacey, Caitlin E Littlefield, Alexander Lowe, Shannon Newman, Vera Okolo, Savannah Olroyd, Brandon R Peecook, Sarah B Pickett, David L Slager, Itzue W Caviedes-Solis, Kathryn E Stanchak, Vasudha Sundaravardan, Camila Valdebenito, Claire R Williams, Kaitlin Zinsli, and Scott Freeman

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Multiplatform Integrative Analysis of Immunogenomic Data for Biomarker Discovery., Vésteinn Thorsson

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Sequential Wnt Agonist Then Antagonist Treatment Accelerates Tissue Repair and Minimizes Fibrosis., Xiao-Jun Tian, Dong Zhou, Haiyan Fu, Rong Zhang, Xiaojie Wang, Sui Huang, Youhua Liu, and Jianhua Xing

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Angiotensin Converting Enzyme Inhibitors and Angiotensin Receptor Blockers and the Risk of SARS-CoV-2 Infection or Hospitalization With COVID-19 Disease: A Systematic Review and Meta-Analysis., Imad M Tleyjeh, Aref A Bin Abdulhak, Haytham Tlayjeh, Mouaz H Al-Mallah, M Rizwan Sohail, Leslie C Hassett, Jolanta M Siller-Matula, and Tarek Kashour

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Preface., Laurence C Torsher, Richard P Dutton, Thomas M McLoughlin, and Francis V Salinas

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Sodium Glucose Cotransporter 2 Inhibition Heralds a Call-to-Action for Diabetic Kidney Disease., Katherine Tuttle, David Z Cherney, and Diabetic Kidney Disease Task Force of the American Society of Nephrology

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Evaluating the Regional Uptake of Minimally Invasive Colorectal Surgery: a Report from the Surgical Care Outcomes Assessment Program., Kenley R Unruh, Amir Bastawrous, Greta V Bernier, David R Flum, Anjali S Kumar, Ravi Moonka, Richard C Thirlby, and Vlad V Simianu

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The optimal treatment of stage I nonsmall cell lung cancer in the era of SABR and modern day lung resections., Eric Vallieres

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Biofilms of the non-tuberculous Mycobacterium chelonae form an extracellular matrix and display distinct expression patterns, Perla Vega-Dominguez, Eliza Jr Peterson, Min Pan, Alessandro Di Maio, Saumya Singh, Siva Umapathy, Deepak K Saini, Nitin Baliga, and Apoorva Bhatt

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Clinical Research in Hepatology in the COVID-19 Pandemic and Post-Pandemic Era: Challenges and the Need for Innovation., Elizabeth C Verna, Marina Serper, Jaime Chu, Kathleen Corey, Oren K Fix, Karen Hoyt, Kimberly A Page, Rohit Loomba, Ming Li, Gregory T Everson, Michael W Fried, Guadalupe Garcia-Tsao, Norah Terrault, Anna S Lok, Raymond T Chung, and K Rajender Reddy

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Erratum: Viswanathan, A., et al. Battling Glioblastoma: A Novel Tyrosine Kinase Inhibitor with Multi-Dimensional Anti-Tumor Effect (Running Title: Cancer Cells Death Signalling Activation)., Anisha Viswanathan, Aliyu Musa, Akshaya Murugesan, João R Vale, Carlos A M Afonso, Saravanan Konda Mani, Olli Yli-Harja, Nuno R Candeias, and Meenakshisundaram Kandhavelu

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BioHackathon 2015: Semantics of data for life sciences and reproducible research., Rutger A Vos, Toshiaki Katayama, Hiroyuki Mishima, Shin Kawano, Shuichi Kawashima, Jin-Dong Kim, Yuki Moriya, Toshiaki Tokimatsu, Atsuko Yamaguchi, Yasunori Yamamoto, Hongyan Wu, Peter Amstutz, Erick Antezana, Nobuyuki P Aoki, Kazuharu Arakawa, Jerven T Bolleman, Evan Bolton, Raoul J P Bonnal, Hidemasa Bono, Kees Burger, Hirokazu Chiba, Kevin B Cohen, Eric W Deutsch, Jesualdo T Fernández-Breis, Gang Fu, Takatomo Fujisawa, Atsushi Fukushima, Alexander García, Naohisa Goto, Tudor Groza, Colin Hercus, Robert Hoehndorf, Kotone Itaya, Nick Juty, Takeshi Kawashima, Jee-Hyub Kim, Akira R Kinjo, Masaaki Kotera, Kouji Kozaki, Sadahiro Kumagai, Tatsuya Kushida, Thomas Lütteke, Masaaki Matsubara, Joe Miyamoto, Attayeb Mohsen, Hiroshi Mori, Yuki Naito, Takeru Nakazato, Jeremy Nguyen-Xuan, Kozo Nishida, Naoki Nishida, Hiroyo Nishide, Soichi Ogishima, Tazro Ohta, Shujiro Okuda, Benedict Paten, Jean-Luc Perret, Philip Prathipati, Pjotr Prins, Núria Queralt-Rosinach, Daisuke Shinmachi, Shinya Suzuki, Tsuyosi Tabata, Terue Takatsuki, Kieron Taylor, Mark Thompson, Ikuo Uchiyama, Bruno Vieira, Chih-Hsuan Wei, Mark Wilkinson, Issaku Yamada, Ryota Yamanaka, Kazutoshi Yoshitake, Akiyasu C Yoshizawa, Michel Dumontier, Kenjiro Kosaki, and Toshihisa Takagi

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A Comparative Meta-Analysis of Unidisciplinary Psychology and Interdisciplinary Treatment Outcomes Following Acceptance and Commitment Therapy for Adults with Chronic Pain., Kevin E Vowles, Melissa Pielech, Karlyn A Edwards, Mindy L McEntee, and Robert W Bailey

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Integrated Behavioral Treatment for Veterans With Co-Morbid Chronic Pain and Hazardous Opioid Use: A Randomized Controlled Pilot Trial., Kevin E Vowles, Katie Witkiewitz, Karen J Cusack, Wesley P Gilliam, Karen E Cardon, Sarah Bowen, Karlyn A Edwards, Mindy L McEntee, and Robert W Bailey

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Multiomic blood correlates of genetic risk identify presymptomatic disease alterations., Michael Wainberg, Andrew T Magis, John C Earls, Jennifer C Lovejoy, Nasa Sinnott-Armstrong, Gilbert S Omenn, Leroy Hood, and Nathan D Price

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Circulating activated lymphocyte subsets as potential blood biomarkers of cancer progression., Ying-Yi Wang, Na Zhou, Hong-Sheng Liu, Xiao-Lei Gong, Rui Zhu, Xiao-Yuan Li, Zhao Sun, Xu-Hong Zong, Ning-Ning Li, Chang-Ting Meng, Chun-Mei Bai, and Tai-Sheng Li

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Association Analysis of Driver Gene-Related Genetic Variants Identified Novel Lung Cancer Susceptibility Loci with 20,871 Lung Cancer Cases and 15,971 Controls., Yuzhuo Wang, Olga Y Gorlova, Ivan P Gorlov, Meng Zhu, Juncheng Dai, Demetrius Albanes, Stephen Lam, Adonina Tardon, Chu Chen, Gary E Goodman, Stig E Bojesen, Maria Teresa Landi, Mattias Johansson, Angela Risch, Heunz-Erich Wichmann, Heike Bickeboller, David C Christiani, Gad Rennert, Susanne M Arnold, Paul Brennan, John K Field, Sanjay Shete, Loïc Le Marchand, Olle Melander, Hans Brunnstrom, Geoffrey Liu, Rayjean J Hung, Angeline S Andrew, Lambertus A Kiemeney, Shanbeh Zienolddiny, Kjell Grankvist, Mikael Johansson, Neil E Caporaso, Penella J Woll, Philip Lazarus, Matthew B Schabath, Melinda C Aldrich, Victoria L Stevens, Hongxia Ma, Guangfu Jin, Zhibin Hu, Christopher I Amos, and Hongbing Shen

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Upper and Lower Limb Movement Kinematics in Aging, Zheng Wang, Callie Lane, Matthew Terza, Pravin Khemani, Su Lui, Walker S McKinney, and Matthew W Mosconi

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Single-Cell Sequencing-Enabled Hexokinase 2 Assay for Noninvasive Bladder Cancer Diagnosis and Screening by Detecting Rare Malignant Cells in Urine., Zhuo Wang, Jie Chen, Liu Yang, Mingzhe Cao, Yanlan Yu, Rulin Zhang, Heng Quan, Qi Jiang, Yingqi Hua, Wei Wei, Peihua Lu, Jun Wu, and Qihui Shi

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Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models., Ying-Wooi Wan, Rami Al-Ouran, Carl G Mangleburg, Thanneer M Perumal, Tom V Lee, Katherine Allison, Vivek Swarup, Cory C Funk, Chris Gaiteri, Mariet Allen, Minghui Wang, Sarah M Neuner, Catherine C Kaczorowski, Vivek M Philip, Gareth R Howell, Heidi Martini-Stoica, Hui Zheng, Hongkang Mei, Xiaoyan Zhong, Jungwoo Wren Kim, Valina L Dawson, Ted M Dawson, Ping-Chieh Pao, Li-Huei Tsai, Jean-Vianney Haure-Mirande, Michelle E Ehrlich, Paramita Chakrabarty, Yona Levites, Xue Wang, Eric B Dammer, Gyan Srivastava, Sumit Mukherjee, Solveig K Sieberts, Larsson Omberg, Kristen D Dang, James A Eddy, Phil Snyder, Yooree Chae, Sandeep Amberkar, Wenbin Wei, Winston Hide, Christoph Preuss, Ayla Ergun, Phillip J Ebert, David C Airey, Sara Mostafavi, Lei Yu, Hans-Ulrich Klein, Accelerating Medicines Partnership, Alzheimer’s Disease Consortium, Gregory W Carter, David A Collier, Todd E Golde, Allan I Levey, David A Bennett, Karol Estrada, T Matthew Townsend, Bin Zhang, Eric Schadt, Philip L De Jager, Nathan D Price, Nilüfer Ertekin-Taner, Zhandong Liu, Joshua M Shulman, Lara M Mangravite, and Benjamin A Logsdon

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A primary human T-cell spectral library to facilitate large scale quantitative T-cell proteomics., Harshi Weerakoon, Jeremy Potriquet, Alok K Shah, Sarah Reed, Buddhika Jayakody, Charu Kapil, Mukul K Midha, Robert L Moritz, Ailin Lepletier, Jason Mulvenna, John J Miles, and Michelle M Hill

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Development and implementation of a primary care clinic workflow protocol to meet opioid prescribing guidelines., Lori M Weller

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Key Parameters of Tumor Epitope Immunogenicity Revealed Through a Consortium Approach Improve Neoantigen Prediction., Daniel K Wells, Marit M van Buuren, Kristen K Dang, Vanessa M Hubbard-Lucey, Kathleen C F Sheehan, Katie M Campbell, Andrew Lamb, Jeffrey P Ward, John Sidney, Ana B Blazquez, Andrew J Rech, Jesse M Zaretsky, Begonya Comin-Anduix, Alphonsus H C Ng, William Chour, Thomas V Yu, Hira Rizvi, Jia M Chen, Patrice Manning, Gabriela M Steiner, Xengie C Doan, Taha Merghoub, Justin Guinney, Adam Kolom, Cheryl Selinsky, Antoni Ribas, Matthew D Hellmann, Nir Hacohen, Alessandro Sette, James R Heath, Nina Bhardwaj, Fred Ramsdell, Robert D Schreiber, Ton N Schumacher, Pia Kvistborg, and Nadine A Defranoux

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Loss of the neural-specific BAF subunit ACTL6B relieves repression of early response genes and causes recessive autism., Wendy Wenderski, Lu Wang, Andrey Krokhotin, Jessica J Walsh, Hongjie Li, Hirotaka Shoji, Shereen Ghosh, Renee D George, Erik L Miller, Laura Elias, Mark A Gillespie, Esther Y Son, Brett T Staahl, Seung Tae Baek, Valentina Stanley, Cynthia Moncada, Zohar Shipony, Sara B Linker, Maria C N Marchetto, Fred H Gage, Dillon Chen, Tipu Sultan, Maha S Zaki, Jeffrey A Ranish, Tsuyoshi Miyakawa, Liqun Luo, Robert C Malenka, Gerald R Crabtree, and Joseph G Gleeson

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Association between Tunneled Pleural Catheter Use and Infection in Patients Immunosuppressed from Antineoplastic Therapy: A Multicenter Study., Candice L. Wilshire, Shu-Ching Chang, Christopher R Gilbert, Jason A Akulian, Mohammed K AlSarraj, Rachelle Asciak, Benjamin T Bevill, Kevin R Davidson, Ashley Delgado, Horiana B Grosu, Felix J F Herth, Hans J Lee, Justin E Lewis, Fabien Maldonado, David E Ost, Nicholas J Pastis, Najib M Rahman, Chakravarthy B Reddy, Lance J Roller, Trinidad M Sanchez, Samira Shojaee, Henry Steer, Jeffrey Thiboutot, Momen M Wahidi, Amber N Wright, Lonny B Yarmus, and Jed A Gorden

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Electronic Medical Record Inaccuracies: Multicenter Analysis of Challenges with Modified Lung Cancer Screening Criteria., Candice L. Wilshire, Carson C Fuller, Christopher R Gilbert, John R Handy, Kimberly E Costas, Brian Louie, Ralph W Aye, Alexander S Farivar, Eric Vallières, and Jed A Gorden

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Temporal Trends in Tunneled Pleural Catheter Utilization in Patients With Malignancy: A Multicenter Review., Candice L. Wilshire, Christopher R Gilbert, Jed A Gorden, Shu-Ching Chang, Jason A Akulian, Ashley Delgado, Amber N Wright, Mohammed K AlSarraj, Momen M Wahidi, Kevin R Davidson, Rachelle Asciak, Najib M Rahman, Benjamin T Bevill, Justin E Lewis, Nicholas J Pastis, Horiana B Grosu, David E Ost, Felix J F Herth, Hans J Lee, Jeffrey Thiboutot, Lonny B Yarmus, Fabien Maldonado, Lance J Roller, Chakravarthy B Reddy, Trinidad M Sanchez, Samira Shojaee, and Henry Steer

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Not following the rules in guideline care for lung cancer diagnosis and staging has negative impact., Candice L. Wilshire, Joshua R Rayburn, Shu-Ching Chang, Christopher R Gilbert, Brian Louie, Ralph W Aye, Alexander S Farivar, Adam J Bograd, Eric Vallières, and Jed A Gorden

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Siponimod enriches regulatory T and B lymphocytes in secondary progressive multiple sclerosis., Qi Wu, Elizabeth A Mills, Qin Wang, Catherine A Dowling, Caitlyn Fisher, Britany Kirch, Steven K Lundy, David A Fox, Yang Mao-Draayer, AMS04 Study Group, James Bowden, and Stanley Cohan

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SOSTDC1-producing follicular helper T cells promote regulatory follicular T cell differentiation., Xin Wu, Yun Wang, Rui Huang, Qujing Gai, Haofei Liu, Meimei Shi, Xiang Zhang, Yonglin Zuo, Longjuan Chen, Qiwen Zhao, Yu Shi, Fengchao Wang, Xiaowei Yan, Huiping Lu, Senlin Xu, Xiaohong Yao, Lin Chen, Xia Zhang, Qiang Tian, Ziyan Yang, Bo Zhong, Chen Dong, Yan Wang, Xiu-Wu Bian, and Xindong Liu

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Autocatalytic chemical networks at the origin of metabolism., Joana C Xavier, Wim Hordijk, Stuart Kauffman, Mike Steel, and William F Martin

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The Cancer Microbiome: Distinguishing Direct and Indirect Effects Requires a Systemic View., Joao B Xavier, Vincent B Young, Joseph Skufca, Fiona Ginty, Traci Testerman, Alexander T Pearson, Paul Macklin, Amir Mitchell, Ilya Shmulevich, Lei Xie, J Gregory Caporaso, Keith A Crandall, Nicole L Simone, Filipa Godoy-Vitorino, Timothy J Griffin, Katrine L Whiteson, Heather H Gustafson, Daniel J Slade, Thomas M Schmidt, Marina R S Walther-Antonio, Tal Korem, Bobbie-Jo M Webb-Robertson, Mark P Styczynski, W Evan Johnson, Christian Jobin, Jason M Ridlon, Andrew Y Koh, Michael Yu, Libusha Kelly, and Jennifer A Wargo

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Correction to: Small Molecule KRAS Agonist for Mutant KRAS Cancer Therapy., Ke Xu, Dongkyoo Park, Andrew T Magis, Jun Zhang, Wei Zhou, Gabriel L Sica, Suresh S Ramalingam, Walter J Curran, and Xingming Deng

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Epigenetic biotypes of post-traumatic stress disorder in war-zone exposed veteran and active duty males., Ruoting Yang, Aarti Gautam, Derese Getnet, Bernie J Daigle, Stacy Miller, Burook Misganaw, Kelsey R Dean, Raina Kumar, Seid Muhie, Kai Wang, Inyoul Lee, Duna Abu-Amara, Janine D Flory, PTSD Systems Biology Consortium, Leroy Hood, Owen M Wolkowitz, Synthia H Mellon, Francis J Doyle, Rachel Yehuda, Charles R Marmar, Kerry J Ressler, Rasha Hammamieh, and Marti Jett

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Correction: A DNA methylation clock associated with age-related illnesses and mortality is accelerated in men with combat PTSD., Ruoting Yang, Gwyneth W Y Wu, Josine E Verhoeven, Aarti Gautam, Victor I Reus, Jee In Kang, Janine D Flory, Duna Abu-Amara, PTSD Systems Biology Consortium, Leroy Hood, Francis J Doyle, Rachel Yehuda, Charles R Marmar, Marti Jett, Rasha Hammamieh, Synthia H Mellon, and Owen M Wolkowitz

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Combining deep learning with token selection for patient phenotyping from electronic health records., Zhen Yang, Matthias Dehmer, Olli Yli-Harja, and Frank Emmert-Streib

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Diagnosing spinal cord ischemia: Are we doing enough catheter angiography?, Robert J Young, Jason H Huang, and Ruth Thiex

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Predictors of survival following surgical resection of limited-stage small cell lung cancer., Nicolas Zhou, Matthew Bott, Bernard J Park, Eric Vallieres, Candice L. Wilshire, Kazuhiro Yasufuku, Jonathan D Spicer, David R Jones, Boris Sepesi, and Small Cell Lung Cancer Working Group

Predictors of overall survival following surgical resection of small cell lung cancer, N Zhou, KG Mitchell, EM Corsini, DR Jones, MJ Bott, Candice L. Wilshire, SG Swisher, MB Antonoff, DC Rice, GL Walsh, RJ Mehran, WL Hofstetter, JA Roth, and See additional authors in comments

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Measurement of Organ-Specific and Acute-Phase Blood Protein Levels in Early Lyme Disease., Yong Zhou, Shizhen Qin, Mingjuan Sun, Li Tang, Xiaowei Yan, Taek-Kyun Kim, Juan Caballero, Gustavo Glusman, Mary E Brunkow, Mark J Soloski, Alison W Rebman, Carol Scavarda, Denise Cooper, Gilbert S Omenn, Robert L Moritz, Gary P Wormser, Nathan D Price, John N Aucott, and Leroy Hood

Submissions from 2019

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Protein-Catalyzed Capture Agents., Heather D Agnew, Matthew B Coppock, Matthew N Idso, Bert T Lai, JingXin Liang, Amy M McCarthy-Torrens, Carmen M Warren, and James R Heath

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Clinical Data: Sources and Types, Regulatory Constraints, Applications., Stanley C Ahalt, Christopher G Chute, Karamarie Fecho, Gustavo Glusman, Jennifer Hadlock, Casey Overby Taylor, Emily R Pfaff, Peter N Robinson, Harold Solbrig, Casey Ta, Nicholas Tatonetti, and Chunhua Weng

Incidence of incidental findings and the rate of downstream interventions in lung cancer screening: A multistate, community-based healthcare network experience, SE Anton, LC Horslen, CA Henson, Candice L. Wilshire, CR Gilbert, KM Spiegel, JR Rayburn, AS Carlson, CC Fuller, and M Bretta

High variability in radiologist reporting of incidental findings during lung cancer screening in a community-based healthcare network The American, SE Anton, Candice L. Wilshire, See all authors in comments, and CR Gilbert

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Personalized Nutrition: Translating the Science of NutriGenomics Into Practice: Proceedings From the 2018 American College of Nutrition Meeting., Okezie I Aruoma, Sharon Hausman-Cohen, Jessica Pizano, Michael A Schmidt, Deanna M Minich, Yael Joffe, Sebastian Brandhorst, Simon J Evans, and David M Brady

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Genome-scale metabolic model of the rat liver predicts effects of diet restriction., Priyanka Baloni, Vineet Sangar, James T Yurkovich, Max Robinson, Scott Taylor, Christine M Karbowski, Hisham K Hamadeh, Yudong D He, and Nathan D Price