Submissions from 2020
Flt3 ligand augments immune responses to anti-DEC-205-NY-ESO-1 vaccine through expansion of dendritic cell subsets., Nina Bhardwaj, Philip A Friedlander, Anna C Pavlick, Marc S Ernstoff, Brian R Gastman, Brent A Hanks, Brendan Curti, Mark R Albertini, Jason J Luke, Ana B Blazquez, Sreekumar Balan, Davide Bedognetti, Joseph M Beechem, Andrea S Crocker, Leonard D'Amico, Patrick Danaher, Thomas A Davis, Thomas Hawthorne, Bruce W Hess, Tibor Keler, Lisa Lundgren, Chihiro Morishima, Nirasha Ramchurren, Darawan Rinchai, Andres M Salazar, Bob A Salim, Elad Sharon, Laura A Vitale, Ena Wang, Sarah Warren, Michael J Yellin, Mary L Disis, Martin A Cheever, and Steven P Fling
Flt3 ligand augments immune responses to anti-DEC-205-NY-ESO-1 vaccine through expansion of dendritic cell subsets, Nina Bhardwaj, Philip A. Friedlander, Anna C. Pavlick, Marc S. Ernstoff, Brian R. Gastman, Brent A. Hanks, Brendan Curti, Mark R. Albertini, Jason J. Luke, Ana B. Blazquez, Sreekumar Balan, Davide Bedognetti, Joseph M. Beechem, Andrea S. Crocker, Leonard D'Amico, Patrick Danaher, Thomas A. Davis, Thomas Hawthorne, Bruce W. Hess, Tibor Keler, Lisa Lundgren, Chihiro Morishima, Nirasha Ramchurren, Darawan Rinchai, Andres M. Salazar, Bob A. Salim, Elad Sharon, Laura A. Vitale, Ena Wang, Sarah Warren, Michael J. Yellin, Mary L. Disis, Martin A. Cheever, and Steven P. Fling
Integrating multiomics in the practice of diagnostic pathology, Carlo Bifulco
72 Routine use of comprehensive genomic profiling to assess tumor mutational burden across a community health system, Carlo Bifulco, Roshanthi Weerasinghe, Bela Bapat, Alexa K Dowdell, Shwetha Pindikuri, Sheila Reynolds, Nancy Biery, David Ball, Mary Campbell, Thomas R. Ward, Alisha Stein, Brock Schroeder, David Eberhard, and Brian D. Piening
72 Routine use of comprehensive genomic profiling to assess tumor mutational burden across a community health system, Carlo Bifulco, Roshanthi Weerasinghe, Bela Bepat, Alexa K Dowdell, Shwetha Pindikuri, Sheila Reynolds, Nancy Biery, David Ball, Mary Campbell, Thomas R. Ward, Alisha Stein, Brock Schroeder, David Eberhard, and Brian D. Piening
Dendritic Cell Maturation Defines Immunological Responsiveness of Tumors and Radiation, Tiffany Blair, S Bambina, Alejandro F Alice, Gwen Kramer, Jason R Baird, Terry R Medler, V Troesch, Marka R Crittenden, and Michael J. Gough
Dendritic Cell Maturation Defines Immunological Responsiveness of Tumors and Radiation, Tiffany C. Blair, Shelly Bambina, Alejandro F Alice, Gwen Kramer, Terry R Medler, Jason R Baird, Miranda L. Broz, Garth Tormoen, Victoria Troesch, Marka R Crittenden, and Michael J. Gough
Dendritic Cell Maturation Defines Immunological Responsiveness of Tumors to Radiation Therapy., Tiffany C Blair, Shelly Bambina, Alejandro F Alice, Gwen Kramer, Terry R Medler, Jason R Baird, Miranda L Broz, Garth W Tormoen, Victoria Troesch, Marka R Crittenden, and Michael J. Gough
Salvage Lung Resections After Definitive Chemoradiotherapy: A Safe and Effective Oncologic Option., Adam J Bograd, Catherine Mann, Jed A Gorden, Christopher R Gilbert, Alexander S Farivar, Ralph W Aye, Brian Louie, and Eric Vallières
Surgery as a Component of Multimodality Care for Known Stage IIIA-N2 Non-small Cell Lung Cancer., Adam J Bograd and Eric Vallières
Part Two: 8. Immunology, Christine Boley Ed.
CX-2009, a CD166-directed probody drug conjugate (PDC): Results from the first-in-human study in patients (Pts) with advanced cancer including breast cancer (BC)., Valentina Boni, Howard A. Burris III, Joyce F. Liu, Alexandra I. Spira, Hendrik-Tobias Arkenau, Mary J. Fidler, Lee S. Rosen, Randy F. Sweis, Nataliya Volodymyrivna Uboha, Rachel E Sanborn, Bert O'Neil, James J. Harding, Patricia LoRusso, Amy M. Weise, Javier Garcia-Corbacho, Ivan Victoria, John W. Frye, Rachel Li, Mark Stroh, and Funda Meric-Bernstam
The Landscape of Glycogen synthase kinase-3 beta (GSK-3b) Genomic Alterations in Cancer., Brittany A Borden, Yasmine Baca, Joanne Xiu, Fabio Tavora, Ira Winer, Benjamin A Weinberg, Ari M VanderWalde, Sourat Darabi, W Michael Korn, Andrew P Mazar, Francis J Giles, Lorin Crawford, Howard Safran, Wafik S El-Deiry, and Benedito A Carneiro
Transcriptome-wide association study reveals candidate causal genes for lung cancer., Yohan Bossé, Zhonglin Li, Jun Xia, Venkata Manem, Robert Carreras-Torres, Aurélie Gabriel, Nathalie Gaudreault, Demetrius Albanes, Melinda C Aldrich, Angeline Andrew, Susanne Arnold, Heike Bickeböller, Stig E Bojesen, Paul Brennan, Hans Brunnstrom, Neil Caporaso, Chu Chen, David C Christiani, John K Field, Gary E Goodman, Kjell Grankvist, Richard Houlston, Mattias Johansson, Mikael Johansson, Lambertus A Kiemeney, Stephen Lam, Maria T Landi, Philip Lazarus, Loic Le Marchand, Geoffrey Liu, Olle Melander, Gadi Rennert, Angela Risch, Susan M Rosenberg, Matthew B Schabath, Sanjay Shete, Zhuoyi Song, Victoria L Stevens, Adonina Tardon, H-Erich Wichmann, Penella Woll, Shan Zienolddiny, Ma'en Obeidat, Wim Timens, Rayjean J Hung, Philippe Joubert, Christopher I Amos, and James D McKay
PANEL DISCUSSION: Future Directions for Adoptive Cell Therapy, Adrian Bot, Andreas Bader, Christina Coughlin, and Andrew D Weinberg
The Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immunotherapy for the treatment of acute leukemia., Michael M Boyiadzis, Ivan Aksentijevich, Daniel A Arber, John Barrett, Renier J Brentjens, Jill Brufsky, Jorge Cortes, Marcos De Lima, Stephen J Forman, Ephraim J Fuchs, Linda J Fukas, Steven D Gore, Mark R Litzow, Jeffrey S Miller, John M Pagel, Edmund K Waller, and Martin S Tallman
Robotic Partial Nephrectomy versus Minimally Invasive Radical Nephrectomy for Clinical T2a Renal Mass: A Propensity Score Matched Comparison from the ROSULA (Robotic Surgery for Large Renal Mass) Collaborative Group., Aaron W Bradshaw, Riccardo Autorino, Giuseppe Simone, Bo Yang, Robert G Uzzo, Francesco Porpiglia, Umberto Capitanio, James R Porter, Riccardo Bertolo, Andrea Minervini, Clayton Lau, Kenneth Jacobsohn, Akbar Ashrafi, Daniel Eun, Alexander Mottrie, Wesley M White, Luigi Schips, Benjamin J Challacombe, Ottavio De Cobelli, Carmen M Mir, Alessandro Veccia, Alessandro Larcher, Alexander Kutikov, Monish Aron, Prokar Dasgupta, Francesco Montorsi, Inderbir S Gill, Chandru P Sundaram, Jihad Kaouk, and Ithaar H Derweesh
Core Curriculum for Oncology Nursing 6th ed. St. Louis, MO: Elsevier., Jeannine M. Brant, Diane G. Cope, and Marlon G Saria
Imaging center administrators report a lack of physician champion and resources for follow-up as barriers to lung cancer screening implementation in a community-based healthcare network The American Thoracic Society Philadelphia, Pennsylvania, KE Buehler, Candice L. Wilshire, and See all authors in comments
In the last month of life the majority of patients with stage IV non-small cell lung cancer experience in-hospital days and in-hospital death The American Thoracic Society Philadelphia, Pennsylvania, KE Buehler, Candice L. Wilshire, and See all authors in comments
A phase I/II study of HB-201, an arenavirus-based cancer immunotherapy, alone, or in combination with anti-PD-1 in patients with HPV16+ cancers., Bharat Burman, Jiaxin Niu, Rom Leidner, Ding Wang, Debra L. Richardson, Corinne Iacobucci, Andy Hwang, Xiaoping Qing, Igor Matushansky, Dmitriy Zamarin, Alan Loh Ho, David G. Pfister, and Marshall R. Posner
A Pilot Study Comparing the Efficacy of Lactate Dehydrogenase Levels Versus Circulating Cell-Free microRNAs in Monitoring Responses to Checkpoint Inhibitor Immunotherapy in Metastatic Melanoma Patients., Matias A Bustos, Rebecca Gross, Negin Rahimzadeh, Hunter Cole, Linh T Tran, Kevin Tran, Ling Takeshima, Stacey L Stern, Steven O'Day, and Dave Hoon
Integrated Assessment of Circulating Cell-Free MicroRNA Signatures in Plasma of Patients with Melanoma Brain Metastasis., Matias Bustos, Kevin Tran, Negin Rahimzadeh, Rebecca Gross, Selena Y Lin, Yoshiaki Shoji, Tomohiro Murakami, Christine L Boley, Linh T Tran, Hunter Cole, Daniel F Kelly, Steven J O'Day, and Dave Hoon
Acalabrutinib monotherapy in patients with relapsed/refractory chronic lymphocytic leukemia: updated phase 2 results., John C Byrd, William G Wierda, Anna Schuh, Stephen Devereux, Jorge M Chaves, Jennifer R Brown, Peter Hillmen, Peter Martin, Farrukh T Awan, Deborah M Stephens, Paolo Ghia, Jacqueline Barrientos, John M Pagel, Jennifer A Woyach, Kathleen Burke, Todd Covey, Michael Gulrajani, Ahmed Hamdy, Raquel Izumi, Melanie M Frigault, Priti Patel, Wayne Rothbaum, Min Hui Wang, Susan O'Brien, and Richard R Furman
Impact of pulmonary function on pulmonary complications after robotic-assisted thoracoscopic lobectomy., Christopher Cao, Brian E Louie, Franca Melfi, Giulia Veronesi, Rene Razzak, Gaetano Romano, Pierluigi Novellis, Neel K Ranganath, and Bernard J Park
Discovery of driver non-coding splice-site-creating mutations in cancer., Song Cao, Daniel Cui Zhou, Clara Oh, Reyka G Jayasinghe, Yanyan Zhao, Christopher J Yoon, Matthew A Wyczalkowski, Matthew H Bailey, Terrence Tsou, Qingsong Gao, Andrew Malone, Sheila Reynolds, Ilya Shmulevich, Michael C Wendl, Feng Chen, and Li Ding
PD-1 Blockade in Anaplastic Thyroid Carcinoma., Jaume Capdevila, Lori J Wirth, Thomas Ernst, Santiago Ponce Aix, Chia-Chi Lin, Rodryg Ramlau, Marcus O Butler, Jean-Pierre Delord, Hans Gelderblom, Paolo A Ascierto, Angelica Fasolo, Dagmar Führer, Marie Luise Hütter-Krönke, Patrick M Forde, Anna Wrona, Armando Santoro, Peter M Sadow, Sebastian Szpakowski, Hongqian Wu, Geraldine Bostel, Jason Faris, Scott Cameron, Andreea Varga, and Matthew H Taylor
Comprehensive Analysis of Genetic Ancestry and Its Molecular Correlates in Cancer., Jian Carrot-Zhang, Nyasha Chambwe, Jeffrey S Damrauer, Theo A Knijnenburg, A Gordon Robertson, Christina Yau, Wanding Zhou, Ashton C Berger, Kuan-Lin Huang, Justin Y Newberg, R Jay Mashl, Alessandro Romanel, Rosalyn W Sayaman, Francesca Demichelis, Ina Felau, Garrett M Frampton, Seunghun Han, Katherine A Hoadley, Anab Kemal, Peter W Laird, Alexander J Lazar, Xiuning Le, Ninad Oak, Hui Shen, Christopher K Wong, Jean C Zenklusen, Elad Ziv, Cancer Genome Atlas Analysis Network, Andrew D Cherniack, and Rameen Beroukhim
Margetuximab plus pembrolizumab in patients with previously treated, HER2-positive gastro-oesophageal adenocarcinoma (CP-MGAH22-05): a single-arm, phase 1b-2 trial., Daniel V T Catenacci, Yoon-Koo Kang, Haeseong Park, Hope E Uronis, Keun-Wook Lee, Matthew C H Ng, Peter C Enzinger, Se Hoon Park, Philip J Gold, Jill Lacy, Howard S Hochster, Sang Cheul Oh, Yeul Hong Kim, Kristen A Marrone, Ronan J Kelly, Rosalyn A Juergens, Jong Gwang Kim, Johanna C Bendell, Thierry Alcindor, Sun Jin Sym, Eun-Kee Song, Cheng Ean Chee, Yee Chao, Sunnie Kim, A Craig Lockhart, Keith L Knutson, Jennifer Yen, Aleksandra Franovic, Jeffrey L Nordstrom, Daner Li, Jon Wigginton, Jan K Davidson-Moncada, Minori Koshiji Rosales, Yung-Jue Bang, and CP-MGAH22-5 Study Group
Minimally Invasive Esophagectomy: A Consensus Statement., Robert J Cerfolio, Anne-Sophie Laliberte, Shanda Blackmon, Jelle P Ruurda, Richard van Hillegersberg, Inderpal Sarkaria, and Brian Louie
Society for Immunotherapy of Cancer clinical and biomarkers data sharing resource document: Volume II-practical challenges., Alessandra Cesano, Michael A Cannarile, Sacha Gnjatic, Bruno Gomes, Justin Guinney, Vaios Karanikas, Mohan Karkada, John M Kirkwood, Beatrix Kotlan, Giuseppe V Masucci, Els Meeusen, Anne Monette, Aung Naing, Vésteinn Thorsson, Nicholas Tschernia, Ena Wang, Daniel K Wells, Timothy L Wyant, and Sergio Rutella
Hysterectomy Versus Hysteropexy at the Time of Native Tissue Pelvic Organ Prolapse Repair: A Cost-Effectiveness Analysis., Olivia H Chang, Jonathan P Shepherd, Beri M Ridgeway, and Lauren A Cadish
Patient-reported outcomes at discontinuation of anti-angiogenesis therapy in the randomized trial of chemotherapy with bevacizumab for advanced cervical cancer: an NRG Oncology Group study., Dana Chase, Helen Q Huang, Bradley J Monk, Lois Michelle Ramondetta, Richard T Penson, Karen Gil, Lisa M Landrum, Mario Leitao, Ana Oaknin, Warner K Huh, Heather L Pulaski, Katina Robison, Saketh R Guntupalli, Debra Richardson, Ritu Salani, Michael W Sill, Lari B Wenzel, and Krishnansu S Tewari
Allosteric inhibitor of β-catenin selectively targets oncogenic Wnt signaling in colon cancer., Anton Cheltsov, Natsuko Nomura, Venkata Mahidhar Yenugonda, Jatin Roper, Rajesh Mukthavaram, Pengfei Jiang, Nam-Gu Her, Ivan Babic, Santosh Kesari, and Elmar Nurmemmedov
Enhanced B7-H4 expression in gliomas with low PD-L1 expression identifies super-cold tumors., Di Chen, Gaopeng Li, Chunxia Ji, Qiqi Lu, Ying Qi, Chao Tang, Ji Xiong, Jian Hu, Fatma Betul Aksoy Yasar, Yan Zhang, Dave S B Hoon, Yu Yao, and Liangfu Zhou
Cancer Systems Biology in the Era of Single-Cell Multi-Omics., Hanjun Cheng, Rong Fan, and Wei Wei
Multimodality screening and prevention of cervical cancer in sub-Saharan Africa: a collaborative model., Justine Chinn and Krishnansu S Tewari
1258O Amivantamab (JNJ-61186372), an EGFR-MET bispecific antibody, in combination with lazertinib, a 3rd-generation tyrosine kinase inhibitor (TKI), in advanced EGFR NSCLC, BC Cho, KH Lee, EK Cho, D-W Kim, J-S Lee, J-Y Han, S-W Kim, A Spira, EB Haura, EK Sabari, Rachel E Sanborn, JM Bauml, JE Gomez, P Lorenzini, JR Infante, J Xie, N Haddish-Berhane, M Thayu, RE Knoblauch, and K Park
A phase II trial evaluating the efficacy of high-dose Radioiodinated Tositumomab (Anti-CD20) antibody, etoposide and cyclophosphamide followed by autologous transplantation, for high-risk relapsed or refractory non-hodgkin lymphoma., Victor A Chow, Joseph G Rajendran, Darrell R Fisher, Frederick R Appelbaum, Ryan D Cassaday, Paul S Martin, Leona A Holmberg, Theodore A Gooley, Philip A Stevenson, John M Pagel, Damian J Green, Oliver W Press, and Ajay K Gopal
Impact of chemotherapy (chemo) on t-cell maturation and clonal proliferation in early-stage and metastatic breast cancer, Brie Chun, Joanna Pucilowska, Valerie Conrad, Mark Schmidt, Isaac Kim, Paul Fields, Alison Conlin, Heather McArthur, and David B Page
Unique challenges for glioblastoma immunotherapy - Discussions across neuro-oncology and non-neuro-oncology experts in cancer immunology., Pavlina Chuntova, Frances Chow, Payal Watchmaker, Mildred Galvez, Amy B Heimberger, Evan W Newell, Aaron Diaz, Ronald A DePinho, Ming O Li, E John Wherry, Duane Mitchell, Masaki Terabe, Derek A Wainwright, Jay A Berzofsky, Christel Herold-Mende, James R Heath, Michael Lim, Kim A Margolin, E Antonio Chiocca, Noriyuki Kasahara, Benjamin M Ellingson, Christine Brown, Yvonne Chen, Peter Fecci, David A Reardon, Gavin P Dunn, Linda M Liau, Joseph F Costello, Wolfgang Wick, Timothy Cloughesy, William C Timmer, Patrick Y Wen, Robert M Prins, Michael Platten, and Hideho Okada
Oncology Care Delivery in the COVID-19 Pandemic: An Opportunity to Study Innovations and Outcomes., Pelin Cinar, John Cox, Arif Kamal, Kathleen Bickel, Monika Krzyzanowska, James Armitage, Apar Kishor Ganti, Jeffery C Ward, Sandra Wong, Sagar Lonial, and Linda Bosserman
Robotic surgery for gynecologic cancers: indications, techniques and controversies., Kiran H Clair and Krishnansu S Tewari
Results of a randomized phase IIb trial of nelipepimut-S + trastuzumab vs trastuzumab to prevent recurrences in high-risk HER2 low-expressing breast cancer patients., G Travis Travis Clifton, Diane Hale, Timothy J Vreeland, Annelies T Hickerson, Jennifer K Litton, Gheath Alatrash, Rashmi K Murthy, Na Qiao, Anne V Philips, Jason J Lukas, Jarrod P Holmes, George E Peoples, and Elizabeth A Mittendorf
976TiP SPEARHEAD-2 trial design: A phase II pilot trial of ADP-A2M4 in combination with pembrolizumab in patients with recurrent or metastatic head and neck cancer, EE Cohen, L Dunn, P Neupane, M Gibson, Rom Leidner, P Savvides, N Hyland, T Trivedi, M Dudley, S Biswas, D Williams, and E Norry
Patient-reported outcomes from KATHERINE: A phase 3 study of adjuvant trastuzumab emtansine versus trastuzumab in patients with residual invasive disease after neoadjuvant therapy for human epidermal growth factor receptor 2-positive breast cancer., PierFranco Conte, Andreas Schneeweiss, Sibylle Loibl, Eleftherios P Mamounas, Gunter von Minckwitz, Max S Mano, Michael Untch, Chiun-Sheng Huang, Norman Wolmark, Priya Rastogi, Veronique D'Hondt, Andrés Redondo, Ljiljana Stamatovic, Hervé Bonnefoi, Hugo Castro-Salguero, Hans H Fischer, Tanya Wahl, Chunyan Song, Thomas Boulet, Peter Trask, and Charles E Geyer
Implementation of human papillomavirus video education for women participating in mass cervical cancer screening in Tanzania., Emma C Cooper, Justine A Maher, Ariana Naaseh, Elizabeth W Crawford, Justine O Chinn, Ava S Runge, Alexa N Lucas, Danielle C Zezoff, Kevin R Bera, Andreea I Dinicu, Kayla M White, Sujata E Tewari, Anjali Hari, Megan Bernstein, Jenny Chang, Argyrios Ziogas, Diana C Pearre, and Krishnansu S Tewari
Impact of Late Dosing on Testosterone Suppression with Two Different Leuprolide Acetate Formulations: In Situ Gel and Microsphere - An Analysis of US Clinical Data., E David Crawford, Jason M Hafron, Scott T Tagawa, Przemyslaw Twardowski, Richard G Harris, Judd W Moul, Thomas E Keane, Raoul S Concepcion, Celestia S Higano, Lucio N Gordan, Daniel P Petrylak, Chaundre K Cross, A Karim Kader, and Neal D Shore
The Impact of Late Luteinizing Hormone-Releasing Hormone Agonist Dosing on Testosterone Suppression in Patients with Prostate Cancer: An Analysis of United States Clinical Data., E David Crawford, Przemyslaw Twardowski, Raoul S Concepcion, Jason M Hafron, Richard G Harris, Judd W Moul, Lucio N Gordan, Daniel P Petrylak, Stuart N Atkinson, Deborah M Boldt-Houle, Thomas E Keane, Celestia S Higano, R Jonathan Henderson, A Karim Kader, Maha H Hussain, and Neal D Shore
Feasibility of Treating High Grade Gliomas in Children with Tumor-Treating Fields: A Case Series., John Crawford, Marlon G Saria, Girish Dhall, Ashley Margol, and Santosh Kesari
Oncoplastic breast-conserving therapy and intraoperative radiotherapy for management of carcinoma in situ of the breast: A single-center experience., Angelena Crown, Elizabeth Carlson, Flavio G Rocha, and Janie Grumley
ASO Author Reflections: Oncoplastic Surgery Does Not Compromise Surveillance Imaging., Angelena Crown and Janie Grumley
Oncoplastic Breast-Conserving Surgery: Can We Reduce Rates of Mastectomy and Chemotherapy Use in Patients with Traditional Indications for Mastectomy?, Angelena Crown, Nicketti Handy, Christina Weed, Ruby Laskin, Flavio G Rocha, and Janie Grumley
Evaluating Need for Additional Imaging and Biopsy After Oncoplastic Breast-Conserving Surgery., Angelena Crown, Ruby Laskin, Christina Weed, Flavio G Rocha, and Janie Grumley
Efficacy of bendamustine and rituximab in unfit patients with previously untreated chronic lymphocytic leukemia. Indirect comparison with ibrutinib in a real-world setting. A GIMEMA-ERIC and US study., Antonio Cuneo; Anthony R Mato; Gian Matteo Rigolin; Alfonso Piciocchi; Massimo Gentile; Luca Laurenti; John N Allan; John M Pagel; Danielle M Brander; Brian T Hill; Allison Winter; Nicole Lamanna; Constantine S Tam; Ryan Jacobs; Frederick Lansigan; Paul M Barr; Mazyar Shadman; Alan P Skarbnik; Jeffrey J Pu; Alison R Sehgal; Stephen J Schuster; Nirav N Shah; Chaitra S Ujjani; Lindsey Roeker; Ester Maria Orlandi; Atto Billio; Livio Trentin; Martin Spacek; Monia Marchetti; Alessandra Tedeschi; Fiorella Ilariucci; Gianluca Gaidano; Michael Doubek; Lucia Farina; Stefano Molica; Francesco Di Raimondo; Marta Coscia; Francesca Romana Mauro; Javier de la Serna; Angeles Medina Perez; Isacco Ferrarini; Giuseppe Cimino; Maurizio Cavallari; Rosalba Cucci; Marco Vignetti; Robin Foà; Paolo Ghia; and GIMEMA, European Research Initiative (ERIC) on CLL, US study group
Randomized phase II study of stereotactic body radiotherapy and interleukin-2 versus interleukin-2 in patients with metastatic melanoma., Brendan Curti, Marka R Crittenden, Steven K Seung, Christopher B Fountain, Roxanne Payne, ShuChing Chang, Jessica Fleser, Kimberly Phillips, Ian Malkasian, Lyn B Dobrunick, and Walter Urba
Multi-Center Analysis of Liver Transplantation for Combined Hepatocellular Carcinoma-Cholangiocarcinoma Liver Tumors., Leigh Anne Dageforde, Neeta Vachharajani, Parissa Tabrizian, Vatche Agopian, Karim Halazun, Erin Maynard, Kristopher Croome, David Nagorney, Johnny C Hong, David Lee, Cristina Ferrone, Erin Baker, William Jarnagin, Alan Hemming, Gabriel Schnickel, Shoko Kimura, Ronald Busuttil, Jessica Lindemann, Sander Florman, Matthew L Holzner, Rami Srouji, Marc Najjar, Lavanya Yohanathan, Jane Cheng, Hiral Amin, Charles A Rickert, Ju Dong Yang, Joohyun Kim, Jennifer Pasko, William C Chapman, and Maria B Majella Doyle
Genome-wide association study of INDELs identified four novel susceptibility loci associated with lung cancer risk., Juncheng Dai, Mingtao Huang, Christopher I Amos, Rayjean J Hung, Adonina Tardon, Angeline Andrew, Chu Chen, David C Christiani, Demetrius Albanes, Gadi Rennert, Jingyi Fan, Gary E Goodman, Geoffrey Liu, John K Field, Kjell Grankvist, Lambertus A Kiemeney, Loic Le Marchand, Matthew B Schabath, Mattias Johansson, Melinda C Aldrich, Mikael Johansson, Neil Caporaso, Philip Lazarus, Stephan Lam, Stig E Bojesen, Susanne Arnold, Maria Teresa Landi, Angela Risch, H-Erich Wichmann, Heike Bickeboller, Paul Brennan, Sanjay Shete, Olle Melander, Hans Brunnstrom, Shan Zienolddiny, Penella Woll, Victoria Stevens, Zhibin Hu, and Hongbing Shen
Review of Radium-223 and Metastatic Castration-Sensitive Prostate Cancer., Savita V Dandapani, Jeffrey Wong, and Przemyslaw Twardowski
Molecular genomic profiling of adrenocortical cancers in clinical practice., Sourat Darabi, David R Braxton, Burton L Eisenberg, and Michael J Demeure
Predictive Biomarkers for Immunotherapy Response Beyond PD-1/PD-L1., Sourat Darabi, David R Braxton, Burton L Eisenberg, and Michael J Demeure
Impact of geography and travel distance on outcomes in epithelial ovarian cancer: a national cancer database analysis., Ava Daruvala, F Lee Lucas, Jesse Sammon, Christopher Darus, and Leslie Bradford
368 REVEAL: Phase 1 dose-escalation study of NKTR-262, a novel TLR7/8 agonist, plus bempegaldesleukin: local innate immune activation and systemic adaptive immune expansion for treating solid tumors, Adi Daub, Brendan Curti, Mehmet Bilen, Andrew Brohl, Evidio Domingo-Musibay, Erkut Borazanci, Christine Fanton, Cat Haglund, Mona Vimal, Mann Muhsin, Mario Marcondes, Anh Nguyen, Mary Tagliaferri, Wei Lin, Jonathan Zalevsky, and Sandra D'Angelo
420 Progression-free survival and biomarker correlates of response with BEMPEG plus NIVO in previously untreated patients with metastatic melanoma: results from the PIVOT-02 study, Adi Daub, Scott Tykodi, Gregory Daniels, Michele Maio, Brendan Curti, Karl Lewis, Sekwon Jang, Ewa Kalinka, Igor Puzanov, Alexander Spira, Daneil Cho, Shanhong Guan, Erika Puente, Ute Hoch, Sue Currie, Tuan Nguyen, Wei Lin, Mary Tagliaferri, Jonathan Zalevsky, Mario Sznol, and Michael Hurwitz
Olaparib for Metastatic Castration-Resistant Prostate Cancer., Johann de Bono, Joaquin Mateo, Karim Fizazi, Fred Saad, Neal Shore, Shahneen Sandhu, Kim N Chi, Oliver Sartor, Neeraj Agarwal, David Olmos, Antoine Thiery-Vuillemin, Przemyslaw Twardowski, Niven Mehra, Carsten Goessl, Jinyu Kang, Joseph Burgents, Wenting Wu, Alexander Kohlmann, Carrie A Adelman, and Maha Hussain
Characterizing diversity in the tumor-immune microenvironment of distinct subclasses of gastroesophageal adenocarcinomas., S Derks, L K de Klerk, X Xu, T Fleitas, K X Liu, Y Liu, F Dietlein, C Margolis, A M Chiaravalli, A C Da Silva, S Ogino, F G Akarca, G J Freeman, S J Rodig, J L Hornick, E van Allen, B Li, S X Liu, V Thorsson, and A J Bass
368 REVEAL: Phase 1 dose-escalation study of NKTR-262, a novel TLR7/8 agonist, plus bempegaldesleukin: local innate immune activation and systemic adaptive immune expansion for treating solid tumors, Abi Diab, Brendan Curti, Mehmet Bilen, Andrew Brohl, Evidio Domingo-Musibay, Erkut Borazanci, Christine Falon, Cat Haglund, Mona Vimal, Mann Muhsin, Mario Marcondes, Anh Nguyen, Mary Tagliaferri, Wei Lin, Jonathan Zalevsky, and Sandra D'Angelo
Bempegaldesleukin (NKTR-214) plus Nivolumab in Patients with Advanced Solid Tumors: Phase I Dose-Escalation Study of Safety, Efficacy, and Immune Activation (PIVOT-02)., Adi Diab, Nizar M Tannir, Salah-Eddine Bentebibel, Patrick Hwu, Vassiliki Papadimitrakopoulou, Cara Haymaker, Harriet M Kluger, Scott N Gettinger, Mario Sznol, Scott S Tykodi, Brendan Curti, Mary A Tagliaferri, Jonathan Zalevsky, Alison L Hannah, Ute Hoch, Sandra Aung, Christie Fanton, Ahsan Rizwan, Ernesto Iacucci, Yijie Liao, Chantale Bernatchez, Michael E Hurwitz, and Daniel C Cho
420 Progression-free survival and biomarker correlates of response with BEMPEG plus NIVO in previously untreated patients with metastatic melanoma: results from the PIVOT-02 study, Adi Diab, Scott Tykodi, Gregory Daniels, Michele Maio, Brendan Curti, Karl Lewis, Sekwon Jang, Ewa Kalinka, Igor Puzanov, Alexander Spira, Daniel Cho, Shanhong Guan, Erika Puente, Ute Hoch, Sue Currie, Tuan Nguyen, Wei Lin, Mary Tagliaferri, Jonathan Zalevsky, Mario Sznol, and Michael Hurwitz
420 Progression-free survival and biomarker correlates of response with BEMPEG plus NIVO in previously untreated patients with metastatic melanoma: results from the PIVOT-02 study, Adi Diab, Scott Tykodi, Gregory Daniels, Michele Maio, Brendan Curti, Karl Lewis, Sekwon Jang, Ewa Kalinka, Igor Puzanov, Alexander Spira, Daniel Cho, Shanhong Guan, Erika Puente, Ute Hoch, Sue Currie, Tuan Nguyen, Wei Lin, Mary Tagliaferri, Jonathan Zalevsky, Mario Sznol, and Michawl Hurwitz
Autologous mastectomy reconstruction: Communication among the breast surgery team to maximize aesthetic and oncologic outcome., Brian P Dickinson, Dennis Holmes, Nikkie Vu-Huynh, Monica B Vu, Lincoln Snyder, Heather MacDonald, Lisa Guerra, Colleen Coleman, Crystal Fancher, Nahid Hamoui, Sadia Khan, Sadie Kim, January Lopez, Jennifer Overstreet, and Peter H Ashjian
Disparities in Amputation Rates for Non-metastatic Extremity Soft Tissue Sarcomas and the Impact on Survival., Joshua C Dilday, Daniel W Nelson, Trevan D Fischer, and Melanie Goldfarb
Genomic, proteomic, and immunologic associations with a durable complete remission of measurable metastatic melanoma induced by a patient-specific dendritic cell vaccine., Robert O Dillman, Gabriel I Nistor, and Aleksandra J Poole
Glioblastoma Multiforme Stem Cell Cycle Arrest by Alkylaminophenol Through the Modulation of EGFR and CSC Signaling Pathways., Phuong Doan, Aliyu Musa, Akshaya Murugesan, Vili Sipilä, Nuno R Candeias, Frank Emmert-Streib, Pekka Ruusuvuori, Kirsi Granberg, Olli Yli-Harja, and Meenakshisundaram Kandhavelu
Evolution of a 4-Benzyloxy-benzylamino Chemotype to Provide Efficacious, Potent, and Isoform Selective PPARα Agonists as Leads for Retinal Disorders., Xiaozheng Dou, Dinesh Nath, Henry Shin, Elmar Nurmemmedov, Philip C Bourne, Jian-Xing Ma, and Adam S Duerfeldt
Scrotal and Penile Erythrodysesthesia Associated with Neoadjuvant Capecitabine Chemoradiation., Julie Dricken, Erica Pettke, John A Griffin, Henry Y Li, and Vivek Mehta
CRI iAtlas: an interactive portal for immuno-oncology research., James A Eddy, Vésteinn Thorsson, Andrew E Lamb, David L Gibbs, Carolina Heimann, Jia Xin Yu, Verena Chung, Yooree Chae, Kristen Dang, Benjamin G Vincent, Ilya Shmulevich, and Justin Guinney
A phase II, open-label study of tomivosertib (eFT508) added on to continued checkpoint inhibitor therapy in patients (pts) with insufficient response to single-agent treatment., Anthony B. El-Khoueiry, Nishan Tchekmedyian, Rachel E Sanborn, Julio Antonio Peguero, Kerry Pulver, Vekas Dembla, Jacob Stephen Thomas, Gary Gene Chiang, Mark Densel, Neil Sankar, Stephen Theodore Worland, Lyon L. Gleich, and Robert S. Sikorski
418 A phase 1, dose escalation and dose expansion study of SQZ PBMC HPV as monotherapy and in combination with atezolizumab in HLA-A*02+ Patients with HPV16+ recurrent, or metastatic solid tumors, Cathy Eng, Joaquina Baranda, Matthew H Taylor, Michael Gordon, Ursula Matulonis, Filip Janku, Martin Kornacker, Asha Kamat, Oliver Rosen, and Antonio Jimeno
418 A phase 1, dose escalation and dose expansion study of SQZ PBMC HPV as monotherapy and in combination with atezolizumab in HLA-A*02+ Patients with HPV16+ recurrent, or metastatic solid tumors, Cathy Eng, Joaquina Baranda, Matthew H Taylor, Michael Gordon, Ursula Matulonis, Filip Janku, Martin Kornacker, Asha Kamat, Oliver Rosen, and Antonio Jimeno
Real-world burden of myelosuppression in patients with small cell lung cancer (SCLC): Retrospective, longitudinal data analysis., Robert S. Epstein, JoAnn Krenitsky, Roshanthi Weerasinghe, Amy S. Parrish, Rachel E Sanborn, and Tehseen Salimi
Design of Development Candidate eFT226, a First in Class Inhibitor of Eukaryotic Initiation Factor 4A RNA Helicase., Justin T Ernst, Peggy A Thompson, Christian Nilewski, Paul A Sprengeler, Samuel Sperry, Garrick Packard, Theodore Michels, Alan Xiang, Chinh Tran, Christopher J Wegerski, Boreth Eam, Nathan P Young, Sarah Fish, Joan Chen, Haleigh Howard, Jocelyn Staunton, Jolene Molter, Jeff Clarine, Andres Nevarez, Gary G Chiang, Jim R Appleman, Kevin R Webster, and Siegfried H Reich
The Combative Language of Cancer: A Plea for an Armistice., Matthew J Farrell
799 Durable responses and immune activation with intratumoral electroporation of pIL-12 plus pembrolizumab in actively progressing anti-PD-1 refractory advanced melanoma: KEYNOTE 695 interim data, Pablo Fernandez-Penas, Matteo Carlino, Katy Tsai, Victoria Atkinson, Monaster Shaheen, Sajeve Thomas, Catalin Mihalcioiu, Tom Van Hagen, Rachel Roberts-Thomson, Andrew Haydon, Andrew Mant, Marcus Butler, Gregory Daniels, Elizabeth Buchbinder, John Hyngstrom, Mecker Moller, Igor Puzanov, C Lance Cowey, Eric Whitman, Carmen Ballesteros-Merino, Shawn M. Jensen, Bernard A Fox, Emmett Schmidt, Clemens Krepler, Scott Diede, Erica Browning, Reneta Hermiz, Lauren Svenson, Jon Salazar, Jack Lee, Christopher Baker, Donna Bannavong, Jendy Sell, Kellie Malloy Foerter, David Canton, Sandra Aung, Christopher Twitty, Alain Algazi, and Adil Daud
799 Durable responses and immune activation with intratumoral electroporation of pIL-12 plus pembrolizumab in actively progressing anti-PD-1 refractory advanced melanoma: KEYNOTE 695 interim data, Pablo Fernandez-Penas, Matteo Carlino, Katy Tsai, Victoria Atkinson, Monater Shaheen, Sajeve Thomas, Catalin Mihalcioiu, Tom Van Hagen, Rachel Roberts-Thomson, Andrew Haydon, Andrew Mant, Marcus Butler, Gregory Daniels, Elizabeth Buchbinder, John Hyngstrom, Mecker Moller, Igor Puzanov, C Lance Cowey, Eric Whitman, Carmen Ballesteros-Merino, Shawn M. Jensen, Bernard A Fox, Emmett Schmidt, Clemens Krepler, Scott Diede, Erica Browning, Reneta Hermiz, Lauren Svenson, Jon Salazar, Jack Lee, Christopher Baker, Donna Bannavong, Jendy Sell, Kellie Malloy Foerter, David Canton, Sandra Aung, Christopher Twitty, Alain Algazi, and Adil Daud
A novel surgeon credentialing and quality assurance process using transoral surgery for oropharyngeal cancer in ECOG-ACRIN Cancer Research Group Trial E3311., Robert L Ferris, Yael Flamand, F Christopher Holsinger, Gregory S Weinstein, Harry Quon, Ranee Mehra, Joaquin J Garcia, Michael L Hinni, Neil D Gross, Erich M Sturgis, Umamaheswar Duvvuri, Eduardo Méndez, John A Ridge, J Scott Magnuson, Kerry A Higgins, Mihir R Patel, Russel B Smith, Daniel W Karakla, Michael E Kupferman, James P Malone, Benjamin L Judson, Jeremy Richmon, Jay O Boyle, Rodrigo Bayon, Bert W O'Malley, Enver Ozer, Giovana R Thomas, Wayne M Koch, Richard Bryan Bell, Nabil F Saba, Shuli Li, Elin R Sigurdson, and Barbara Burtness
Transoral robotic surgical resection followed by randomization to low- or standard-dose IMRT in resectable p16+ locally advanced oropharynx cancer: A trial of the ECOG-ACRIN Cancer Research Group (E3311)., Robert L. Ferris, Yael Flamand, Gregory S. Weinstein, Shuli Li, Harry Quon, Ranee Mehra, Joaquin J. Garcia, Christine H. Chung, Maura L. Gillison, Umamaheswar Duvvuri, Bert W. O'Malley, Enver Ozer, Giovanna R. Thomas, Wayne Koch, Michael Elliot Kupferman, Richard Bryan Bell, Nabil F. Saba, Miriam Lango, Eduardo Mendez, and Barbara Burtness
The Efficacy of Passive Valve Antimicrobial Swab Caps Against Existing Clabsi Prevention Bundle in an Adult Hematology Inpatient Population: A Quality Improvement Initiative, Joseph F. Ferry, Neil Bailey, Vanessa Dunleavy, Joanna Fesler, Judson Hall, Sonia Glennie, William Bensinger, Raya Mawad, Krish Patel, Daniel N Egan, John M Pagel, and Livia Hegerova
Resolution of eicosanoid/cytokine storm prevents carcinogen and inflammation-initiated hepatocellular cancer progression., Anna Fishbein, Weicang Wang, Haixia Yang, Jun Yang, Victoria M Hallisey, Jianjun Deng, Sanne M L Verheul, Sung Hee Hwang, Allison Gartung, Yuxin Wang, Diane R Bielenberg, Sui Huang, Mark W Kieran, Bruce D Hammock, and Dipak Panigrahy
Cetuximab in Patients with Breast Cancer, Non-Small Cell Lung Cancer, and Ovarian Cancer Without KRAS, NRAS, or BRAF Mutations: Results from the Targeted Agent and Profiling Utilization Registry (TAPUR) Study., Julie G Fisher, David Tait, Elizabeth Garrett-Mayer, Susan Halabi, Pam K Mangat, Julian C Schink, Ricardo H Alvarez, Dan Veljovich, Timothy L Cannon, Pamela A Crilley, Theodore Pollock, Carmen J Calfa, Tareq Al Baghdadi, Ramya Thota, Nicole Fleming, Jared A Cotta, Andrew L Rygiel, Sasha L Warren, and Richard L Schilsky
Colon and Rectal Surgery Robotic Training Programs: An Evaluation of Gender Disparities., Katherine E Foley, Kevin M Izquierdo, Madrigal G von Muchow, Amir Bastawrous, Robert K Cleary, and Mark K Soliman
A profile on the FoundationFocus CDxBRCA tests., Lindsey Ford, Juliet E Wolford, Sandra Brown, and Leslie M Randall
The combination of ibrutinib and rituximab demonstrates activity in first-line follicular lymphoma., Nathan H Fowler, Loretta Nastoupil, Sven De Vos, Mark Knapp, Ian W Flinn, Robert Chen, Ranjana H Advani, Sumeet Bhatia, Peter Martin, Raul Mena, Richard Eric Davis, Sattva S Neelapu, Karl Eckert, Jerry Ping, Melannie Co, Darrin M Beaupre, Jutta K Neuenburg, and M Lia Palomba
Cancer vaccines yesterday, today, and tomorrow: Cinderella no more?, Bernard A Fox
Immunotherapy-Induced Anti-Cancer Responses, Bernard A Fox
Immunotherapy-induced anti-cancer responses, Bernard A Fox
443 An immunotherapy trio in advanced HNSCC for coordinated B and T cell antigen response, Bernard A Fox, Tarsem Moudgil, Traci Hilton, Noriko Iwamoto, Christopher Paustian, Adi Mehta, Fridtjof Lund-Johansen, Rachel E Sanborn, Richard Bryan Bell, Madeleine Laws, Glenna McDonnell, Yoshinobu Koguchi, Carlo Bifulco, Brian D. Piening, Carmen Ballesteros-Merino, Shawn M. Jensen, Takashi Shimada, Hong-Ming Hu, Walter Urba, Rom Leidner, and Marcus Couey
443 An immunotherapy trio in advanced HNSCC for coordinated B and T cell antigen response, Bernard A Fox, Tarsem Moudgil, Traci Hilton, Noriko Iwamoto, Christopher Paustian, Adi Mehta, Fridtjof Lund-Johansen, Rachel E Sanborn, Richard Bryan Bell, Madeline Laws, Glenna McDonnell, Yoshinobu Koguchi, Carlo Bifulco, Brian D. Piening, Carmen Ballesteros-Merino, Shawn M. Jensen, Takashi Shimada, Hong-Ming Hu, Walter Urba, Rom Leidner, and Marcus Couey
Immunoscore as a parameter predicting time to recurrence and disease-free survival in T4N0 stage II colon cancer patients., Jerome Galon, Fabienne Hermitte, Bernhard Mlecnik, Alessandro Lugli, Carlo Bifulco, Iris D. Nagtegaal, Arndt Hartmann, Florence Marliot, Marc Van Den Eynde, Michael H.A. Roehrl, Pamela S. Ohashi, Eva Zavadova, Toshihiko Torigoe, Prabhudas S. Patel, Yili Wang, Yutaka Kawakami, Francesco Marincola, Paolo Antonio Ascierto, Bernard A Fox, and Franck Pages
Prognostic Impact and Utility of Immunoprofiling in the Selection of Patients with Colorectal Peritoneal Carcinomatosis for Cytoreductive Surgery (CRS) and Heated Intraperitoneal Chemotherapy (HIPEC)., Mary Garland-Kledzik, Abhineet Uppal, Yalda Naeini, Stacey L Stern, Richard Erali, Anthony J Scholer, Adam Khader, Juan A Santamaria-Barria, Kathleen Cummins-Perry, Yi Zhou, Konstantinos I Votanopoulos, Perry Shen, Edward A Levine, and Anton J Bilchik
