The Cancer Institute is a leader in cutting-edge treatments. Using a truly multidisciplinary approach, patients have access to advanced diagnostics, minimally invasive surgical interventions, and personalized genomic and immune-oncologic treatment options. Our team of cancer specialists – many of whom completed fellowships and specialty training at prestigious academic centers – offers comprehensive services for individuals with a cancer diagnosis.

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Submissions from 2021

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Clinical implementation of automated treatment planning for whole-brain radiotherapy., Eun Young Han, Carlos E Cardenas, Callistus Nguyen, Donald Hancock, Yao Xiao, Raymond Mumme, Laurence E Court, Dong Joo Rhee, Tucker J Netherton, Jing Li, Debra Nana Yeboa, Chenyang Wang, Tina M Briere, Peter Balter, Mary K Martel, and Zhifei Wen

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Hepatic Plexus Nerve Block for Microwave Ablation of Hepatic Tumors., Frank Hao, Navid Eghbalieh, Alexandra So, and Edward Wolfgang Lee

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LB180 - Clinical biomarker studies with two fusion-enhanced versions of oncolytic HSV (RP1 and RP2) alone and in combination with nivolumab in cancer patients indicate potent immune activation, Kevin J. Harrington, Francesca Aroldi, Joseph J. Sacco, Mohammed M. Milhem, Brendan Curti, Ari M. Vanderwalde, Scott Baum, Adel Samson, Anna C. Pavlick, Jason A. Chesney, Jiaxin Niu, Terence D. Rhodes, Tawnya L. Bowles, Robert Conry, Anna Olsson-Brown, Douglas E. Laux, Pablo Nenclares, Lavita Menezes, Alex Deterding, Victoria Roulstone, Joan Kyula, Suzanne Thomas, Praveen K. Bommareddy, Selda Samakoglu, Andrea Pirzkall, Robert S. Coffin, and Mark R. Middleton

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The frequency of medical reversals in a cross-sectional analysis of high-impact oncology journals, 2009-2018., Alyson Haslam, Jennifer Gill, Tyler Crain, Diana Herrera-Perez, Emerson Y Chen, Talal Hilal, Myung S Kim, and Vinay Prasad

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The frequency of assessment of progression in randomized oncology clinical trials., Alyson Haslam, Jennifer Gill, and Vinay Prasad

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Correction to: Physician-directed genetic screening to evaluate personal risk for medically actionable disorders: a large multi-center cohort study., Eden V Haverfield, Edward D Esplin, Sienna J Aguilar, Kathryn E Hatchell, Kelly E Ormond, Andrea Hanson-Kahn, Paldeep S Atwal, Sarah Macklin-Mantia, Stephanie Hines, Caron W-M Sak, Steven Tucker, Steven B Bleyl, Peter J Hulick, Ora K Gordon, Lea Velsher, Jessica Y J Gu, Scott M Weissman, Teresa Kruisselbrink, Christopher Abel, Michele Kettles, Anne Slavotinek, Bryce A Mendelsohn, Robert C Green, Swaroop Aradhya, and Robert L Nussbaum

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Physician-directed genetic screening to evaluate personal risk for medically actionable disorders: a large multi-center cohort study., Eden V Haverfield, Edward D Esplin, Sienna J Aguilar, Kathryn E Hatchell, Kelly E Ormond, Andrea Hanson-Kahn, Paldeep S Atwal, Sarah Macklin-Mantia, Stephanie Hines, Caron W-M Sak, Steven Tucker, Steven B Bleyl, Peter J Hulick, Ora K Gordon, Lea Velsher, Jessica Y J Gu, Scott M Weissman, Teresa Kruisselbrink, Christopher Abel, Michele Kettles, Anne Slavotinek, Bryce A Mendelsohn, Robert C Green, Swaroop Aradhya, and Robert L Nussbaum

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Receipt of Tobacco Treatment and One-Year Smoking Cessation Rates Following Lung Cancer Screening in the Veterans Health Administration., Jaimee L Heffner, Scott Coggeshall, Chelle L Wheat, Paul Krebs, Laura C Feemster, Deborah E Klein, Linda Nici, Hannah Johnson, and Steven B Zeliadt

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Digital twins for predictive oncology will be a paradigm shift for precision cancer care., Tina Hernandez-Boussard, Paul Macklin, Emily J Greenspan, Amy L Gryshuk, Eric Stahlberg, Tanveer Syeda-Mahmood, and Ilya Shmulevich

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Impact of Molecular Features of Diffuse Large B-Cell Lymphoma on Treatment Outcomes with Anti-CD19 Chimeric Antigen Receptor (CAR) T-Cell Therapy, Brian T. Hill, Neil Bailey, Krish Patel, John M Pagel, and See full list of authors in comments

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First report of the safety/tolerability and preliminary antitumor activity of HB-201 and HB-202, an arenavirus-based cancer immunotherapy, in patients with HPV16+ cancers., Alan L. Ho, Marshall R. Posner, and Rom Leidner

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Intravenous Cetirizine vs Intravenous Diphenhydramine for the Prevention of Hypersensitivity Infusion Reactions: Results of an Exploratory Phase 2 Study., Jarrod P Holmes, Julio A Peguero, R Campbell Garland, Janine North, Stacia Young, Lonnie D Brent, and Nancy Joseph-Ridge

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Intravenous Cetirizine vs Intravenous Diphenhydramine for the Prevention of Hypersensitivity Infusion Reactions: Results of an Exploratory Phase 2 Study., Jarrod P Holmes, Julio A Peguero, R Campbell Garland, Janine North, Stacia Young, Lonnie D Brent, and Nancy Joseph-Ridge

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Mogamulizumab in Combination with Nivolumab in a Phase I/II Study of Patients with Locally Advanced or Metastatic Solid Tumors., David S Hong, Olivier Rixe, Vi K Chiu, Patrick M Forde, Tomislav Dragovich, Yanyan Lou, Asha Nayak-Kapoor, Rom Leidner, James N Atkins, Agron Collaku, Floyd E Fox, Margaret A Marshall, and Anthony J Olszanski

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EpiMap: Fine-tuning integrative epigenomics maps to understand complex human regulatory genomic circuitry., Dave S B Hoon, Negin Rahimzadeh, and Matias A Bustos

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Reconciling Non-Genetic Plasticity with Somatic Evolution in Cancer., Sui Huang

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A Case of Vaccine-Preventable Back Pain, Gerald Hutfles and Tricia James

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Integrated genetic and metabolic landscapes predict vulnerabilities of temozolomide resistant glioblastoma cells., Selva Rupa Christinal Immanuel, Avinash D Ghanate, Dharmeshkumar S Parmar, Ritu Yadav, Riya Uthup, Venkateswarlu Panchagnula, and Anu Raghunathan

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In Their Voice: What Do Caregivers of Patients with Cancer Need?, Ahlam Jadalla

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The Effects of Cardiorespiratory and Motor Skill Fitness on Intrinsic Functional Connectivity of Neural Networks in Individuals with Parkinson's Disease., Behnaz Jarrahi, Sarah C McEwen, Daniel P Holschneider, Dawn M Schiehser, Andrew J Petkus, Megan E Gomez, Jack D Van Horn, Vincent Filoteo, Michael W Jakowec, and Giselle M Petzinger

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Initial results of a first-in-human, dose escalation study of a cell-based vaccine in HLA A*02+ patients (pts) with recurrent, locally advanced or metastatic HPV16+ solid tumors: SQZ-PBMC-HPV-101., Antonio Jimeno, Joaquina C. Baranda, Matthew H Taylor, and See all authors in comments

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Phase I, First-in-Human Study of the Probody Therapeutic CX-2029 in Adults with Advanced Solid Tumor Malignancies., Melissa Johnson, Anthony El-Khoueiry, Navid Hafez, Nehal Lakhani, Hirva Mamdani, Jordi Rodon, Rachel E Sanborn, Javier Garcia-Corbacho, Valentina Boni, Mark Stroh, Alison L Hannah, Song Wang, Henry Castro, and Alexander Spira

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Effect of prior therapy on tumor mutational burden in NSCLC., Sushma Jonna, Ari Vanderwalde, Jorge Nieva, Kelsey Anne Poorman, Michelle Saul, Xinyu von Buttlar, John Y Hu, and Stephen V Liu

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Toxicity After Stereotactic Body Radiation Therapy for Prostate Cancer in Patients With Inflammatory Bowel Disease: A Multi-institutional Matched Case-Control Series., Jesus E Juarez, Tahmineh Romero, Constantine A Mantz, Abigail Pepin, Nima Aghdam, Simeng Suy, Michael L Steinberg, Rebecca G Levin-Epstein, Nicholas G Nickols, Irving D Kaplan, Robert M Meier, Huong T Pham, Patrick W Linson, Robert L Hong, Mark K Buyyounouski, Hilary P Bagshaw, Donald B Fuller, Alan J Katz, Andrew Loblaw, Sean P Collins, and Amar U Kishan

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Microfluidic Single-Cell Proteomics Assay Chip: Lung Cancer Cell Line Case Study., Yugyung Jung, Minkook Son, Yu Ri Nam, Jongchan Choi, James R Heath, and Sung Yang

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Plexin-B2 orchestrates collective stem cell dynamics via actomyosin contractility, cytoskeletal tension and adhesion., Chrystian Junqueira Alves, Rafael Dariolli, Jonathan Haydak, Sangjo Kang, Theodore Hannah, Robert J Wiener, Stefanie DeFronzo, Rut Tejero, Gabriele L Gusella, Aarthi Ramakrishnan, Rodrigo Alves Dias, Alexandre Wojcinski, Santosh Kesari, Li Shen, Eric A Sobie, José Paulo Rodrigues Furtado de Mendonça, Evren U Azeloglu, Hongyan Zou, and Roland H Friedel

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Results of a randomized phase 3 study of oral sapacitabine in elderly patients with newly diagnosed acute myeloid leukemia (SEAMLESS)., Hagop M Kantarjian, Kebede H Begna, Jessica K Altman, Stuart L Goldberg, Mikkael A Sekeres, Stephen A Strickland, Martha L Arellano, David F Claxton, Maria R Baer, Marc Gautier, Ellin Berman, Karen Seiter, Scott R Solomon, Gary J Schiller, Selina M Luger, Aleksandra Butrym, Gianluca Gaidano, Xavier G Thomas, Pau Montesinos, David A Rizzieri, Donald Quick, Parameswaran Venugopal, Rakesh Gaur, Lori J Maness, Tapan M Kadia, Farhad Ravandi, Marc E Buyse, and Judy H Chiao

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Multi-omic Profiling of Simultaneous Ductal Carcinoma In Situ and Invasive Breast Cancer, Henry G. Kaplan, Anna B. Berry, Alexa Dowdell, and Brian D. Piening

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Treatment of PCM1-JAK2 fusion tyrosine kinase gene-related acute lymphoblastic leukemia with stem cell transplantation, Henry G Kaplan, Carlo Bifulco, Ruyun Jin, James M Scanlan, and David Colvin

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Risk Factors for Intravesical Recurrence after Minimally Invasive Nephroureterectomy for Upper Tract Urothelial Cancer (ROBUUST Collaboration)., Andrew B Katims, Rollin Say, Ithaar Derweesh, Robert Uzzo, Andrea Minervini, Zhenjie Wu, Firas Abdollah, Chandru Sundaram, Matteo Ferro, Koon Rha, Alex Mottrie, Giuseppe Rosiello, Giuseppe Simone, Daniel D Eun, Adam Reese, Laura C Kidd, James R Porter, Amit Satish Bhattu, Mark L Gonzalgo, Vitaly Margulis, Jamil Marcus, Alyssa Danno, Margaret Meagher, Riccardo Tellini, Andrea Mari, Alessandro Veccia, Alireza Ghoreifi, Riccardo Autorino, Hooman Djaladat, and Reza Mehrazin

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Doxorubicin in combination with cisplatin, 5-flourouracil, and vincristine is feasible and effective in unresectable hepatoblastoma: A Children's Oncology Group study., Howard M Katzenstein, Marcio H Malogolowkin, Mark D Krailo, Jin Piao, Alexander J Towbin, M Beth McCarville, Gregory M Tiao, Stephen P Dunn, Max R Langham, Eugene D McGahren, Milton J Finegold, Sarangarajan Ranganathan, Christopher B Weldon, Patrick A Thompson, Angela Trobaugh-Lotrario, Allison F O'Neill, Wayne L Furman, Nadia Chung, Jessica Randazzo, Carlos Rodriguez-Galindo, and Rebecka L Meyers

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Human Breast Extracellular Matrix Microstructures and Protein Hydrogel 3D Cultures of Mammary Epithelial Cells., Chandler R Keller, Yang Hu, Kelsey F Ruud, Anika E VanDeen, Steve R Martinez, Barry T Kahn, Zhiwu Zhang, Roland K Chen, and Weimin Li

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Treatment dependent improvements in survival of stage 2/3 rectal cancer patients treated with trimodality therapy between 2006-2016, an NCDB analysis., Hagen F Kennecke, Henry T. Bahnson, and See list of authors in comments

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CCTG CO.28 primary endpoint analysis: Neoadjuvant chemotherapy, excision and observation for early rectal cancer, the NEO trial., Hagen F Kennecke, Carl J. Brown, and See full list of authors in comments

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Mesenchymal stem cells in the treatment of severe COVID-19., Santosh Kesari, Gregory C Kasper, Lev Verkh, Terese C Hammond, Marla L Matal, Jay W Hammerling, Nikolai Tankovich, Adrianus P Lim, Kevin H Zhao, Tiffany Juarez, Roberta E Redfern, Jaya M Gill, Natsuko Nomura, Audrey Hiemer, Annie Heng, and Jessica Shoemaker

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Response to: Is there any association between a delay in surgery and nodal positivity in the ER-negative Her2 negative breast cancer subgroups?, Adam Khader and Trevan Fischer

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The regulatory saga of fedratinib., Shannon Khal, Vinay Prasad, and Alison Palumbo

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"Custom" Plate in a Day-Accurate Predictive Hole Fabrication Using Point-of-Care 3-Dimensional Printing., Baber Khatib, Marcus Couey, Ashish Patel, Allen C Cheng, and Richard Bryan Bell

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Machine learning models to predict failure in administration of intrapleural tPA/DNase in patients with complicated parapneumonic effusions/empyema: A multicenter study, D Khemasuwan, S Shojaee, C Reddy, CR Gilbert, JA Gorden, A Balwan, S Trinidad, B Bixby, JS Sorensen, and Candice L. Wilshire

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Machine learning models to predict failure in administration of intrapleural tPA/DNase in patients with complicated parapneumonic effusions/empyema: A multicenter study, D Khemasuwan, S Shojaee, C Reddy, CR Gilbert, JA Gorden, A Balwan, S Trinidad, B Bixby, JS Sorensen, and Candice L. Wilshire

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A Case Series of Metastatic Metaplastic Breast Carcinoma Treated With Anti-PD-1 Therapy., Isaac Kim, Venkatesh Rajamanickam, Brady Bernard, Brie Chun, Yaping Wu, Maritza Martel, Zhaoyu Sun, William L Redmond, Katherine Sanchez, Reva Basho, Heather McArthur, and David B Page

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Improved image reconstruction of, Julian Kirchner, Joseph A O'Donoghue, Anton S Becker, and Gary A Ulaner

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Awareness, Knowledge, and Preferences of United States (US) Patients with Chronic Lymphocytic Leukemia (CLL) and Their Caregivers Related to Finite Duration (FD) Therapy and Minimal (Measurable) Residual Disease (MRD), Brian Koffman, Neil Bailey, John M Pagel, and See all authors in comments

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Trough levels of ipilimumab in serum as a potential biomarker of clinical outcomes for patients with advanced melanoma after treatment with ipilimumab., Yoshinobu Koguchi, Noriko Iwamoto, Takashi Shimada, Shu-Ching Chang, John Cha, Brendan Curti, Walter Urba, Brian D. Piening, and William L. Redmond

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Genomic and functional characterization of a mucosal symbiont involved in early-stage colorectal cancer., Melissa C Kordahi, Ian B Stanaway, Marion Avril, Denise Chac, Marie-Pierre Blanc, Benjamin Ross, Christian Diener, Sumita Jain, Paul McCleary, Ana Parker, Vincent Friedman, Jennifer Huang, Wynn Burke, Sean M Gibbons, Amy D Willis, Richard P Darveau, William M Grady, Cynthia W Ko, and R William DePaolo

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Changes in Carcinoid Syndrome Symptoms Among Patients Receiving Telotristat Ethyl in US Clinical Practice: Findings from the TELEPRO-II Real-World Study., Matthew H Kulke, Hagen F Kennecke, Kris Murali, and Vijay N Joish

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Quality Is King: Fundamental Insights into Tumor Antigenicity from Virus-Associated Merkel Cell Carcinoma., Miranda C Lahman, Kelly G Paulson, Paul T Nghiem, and Aude G Chapuis

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An empirical antigen selection method identifies neoantigens that either elicit broad anti-tumor T cell responses or drive tumor growth., Hubert Lam, Lisa K McNeil, Hanna Starobinets, Victoria L DeVault, Roger B Cohen, Przemyslaw Twardowski, Melissa L Johnson, Maura L Gillison, Mark N Stein, Ulka N Vaishampayan, Arthur P DeCillis, James J Foti, Vijetha Vemulapalli, Emily Tjon, Kyle Ferber, Daniel B DeOliveira, Wendy Broom, Parul Agnihotri, Elizabeth M Jaffee, Kwok-Kin Wong, Charles G Drake, Pamela M Carroll, Thomas A Davis, and Jessica Baker Flechtner

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Unaltered IL-2 encapsulated in acoustically active lipid microspheres for systemic but targeted microdose delivery to tumor microenvironment., Clayton Larsen, Llew Keltner, William L. Redmond, and Rhodemann Li

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WNT Signaling as a Therapeutic Target for Glioblastoma., Michael Latour, Nam-Gu Her, Santosh Kesari, and Elmar Nurmemmedov

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Lung cancer diagnosed on pap smear: A case report and review of the literature., Marie-Claire Leaf, Diana Pearre, Fabio Cappuccini, and Krishnansu S Tewari

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Lenvatinib plus pembrolizumab in patients with either treatment-naive or previously treated metastatic renal cell carcinoma (Study 111/KEYNOTE-146): a phase 1b/2 study., Chung-Han Lee, Amishi Yogesh Shah, Drew Rasco, Arpit Rao, Matthew H Taylor, Christopher Di Simone, James J Hsieh, Alvaro Pinto, David R Shaffer, Regina Girones Sarrio, Allen Lee Cohn, Nicholas J Vogelzang, Mehmet Asim Bilen, Sara Gunnestad Ribe, Musaberk Goksel, Øyvind Krohn Tennøe, Donald Richards, Randy F Sweis, Jay Courtright, Daniel Heinrich, Sharad Jain, Jane Wu, Emmett V Schmidt, Rodolfo F Perini, Peter Kubiak, Chinyere E Okpara, Alan D Smith, and Robert J Motzer

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Integrated analysis of plasma and single immune cells uncovers metabolic changes in individuals with COVID-19., Jihoon W Lee, Yapeng Su, Priyanka Baloni, Daniel Chen, Ana Jimena Pavlovitch-Bedzyk, Dan Yuan, Venkata R Duvvuri, Rachel H Ng, Jongchan Choi, Jingyi Xie, Rongyu Zhang, Kim Murray, Sergey A Kornilov, Brett Smith, Andrew T Magis, Dave Hoon, Jennifer J Hadlock, Jason D Goldman, Nathan D Price, Raphael Gottardo, Mark M Davis, Leroy Hood, Philip D Greenberg, and James R Heath

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Cordycepin inhibits the proliferation of malignant peripheral nerve sheath tumor cells through the p53/Sp1/tubulin pathway., Ming-Jen Lee, Jen-Chieh Lee, Jung-Hsien Hsieh, May-Yao Lin, I-An Shih, Huey-Ling You, and Kai Wang

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Molecular interaction of HIC, an agonist of P2Y1 receptor, and its role in prostate cancer apoptosis., Hien Thi Thu Le, Akshaya Murugesan, Thiyagarajan Ramesh, Olli Yli-Harja, Saravanan Konda Mani, and Meenakshisundaram Kandhavelu

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Neoadjuvant immunoradiotherapy results in high rate of complete pathological response and clinical to pathological downstaging in locally advanced head and neck squamous cell carcinoma., Rom Leidner, Marka Crittenden, Kristina Young, Hong Xiao, Yaping Wu, Marcus A Couey, Ashish A Patel, Allen C Cheng, Amber L Watters, Carlo Bifulco, George Morris, Lessli Rushforth, Shorin Nemeth, Walter J Urba, Michael Gough, and R Bryan Bell

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Cancer microenvironment and genomics: evolution in process., Stanley P Leong, Isaac P Witz, Orit Sagi-Assif, Sivan Izraely, Jonathan Sleeman, Brian Piening, Bernard A Fox, Carlo B Bifulco, Rachel Martini, Lisa Newman, Melissa Davis, Lauren M Sanders, David Haussler, Olena M Vaske, and Marlys Witte

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Beyond Sedlis-A novel histology-specific nomogram for predicting cervical cancer recurrence risk: An NRG/GOG ancillary analysis., Kimberly Levinson, Anna L Beavis, Christopher Purdy, Anne F Rositch, Akila Viswanathan, Aaron H Wolfson, Michael G Kelly, Krishnansu S Tewari, Leah McNally, Saketh R Guntupalli, Omar Ragab, Yi-Chun Lee, David S Miller, Warner K Huh, Kelly J Wilkinson, Nicola M Spirtos, Linda Van Le, Yovanni Casablanca, Laura L Holman, Steven E Waggoner, and Amanda N Fader

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Pembrolizumab with low-dose carboplatin for recurrent platinum-resistant ovarian, fallopian tube, and primary peritoneal cancer: survival and immune correlates., John B Liao, William R Gwin, Renata R Urban, Katie M Hitchcock-Bernhardt, Andrew L Coveler, Doreen M Higgins, Jennifer S Childs, Hania N Shakalia, Ron E Swensen, Sasha E Stanton, Anna V Tinker, Tanya A Wahl, Richard G Ancheta, Kathryn F McGonigle, James Y Dai, Mary L Disis, and Barbara A Goff

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Disrupting tumour vasculature and recruitment of aPDL1-loaded platelets control tumour metastasis., Hongjun Li, Zejun Wang, Zhaowei Chen, Tianyuan Ci, Guojun Chen, Di Wen, Ruoxin Li, Jinqiang Wang, Huan Meng, R Bryan Bell, Zhifeng Gu, Gianpietro Dotti, and Zhen Gu

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Measurements of Functional Network Connectivity Using Resting State Arterial Spin Labeling During Neurosurgery., Thomas Lindner, Hajrullah Ahmeti, Michael Helle, Olav Jansen, Jens Fiehler, Lasse Dührsen, Michael Synowitz, Santosh Kesari, and Stephan Ulmer

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Effects of yoga, cognitive behavioral therapy, and a behavioral placebo on sleep: A nationwide multicenter phase III RCT in cancer survivors., Po-Ju Lin, Charles E. Heckler, Alison Conlin, and See full list of authors in comments

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Improved Survival Outcomes in Medically Fit Patients With Early-Stage Non-Small-Cell Lung Cancer Undergoing Stereotactic Body Radiotherapy., Jason Liu, Caressa Hui, Colton Ladbury, Thomas Waddington, Loretta Erhunmwunsee, Dan Raz, Jae Kim, Ravi Salgia, Stafford Chenery, Daryl Pearlstein, Amanda Schwer, and Arya Amini

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Niraparib in the maintenance treatment of advanced epithelial ovarian, fallopian tube, or primary peritoneal cancer: safety and efficacy., Marisa C Liu, Joyce Sutedja, and Krishnansu S Tewari

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Characterization of the immune response in patients with cancer of the oral cavity after neoadjuvant immunotherapy with the IRX-2 regimen., Siyu Liu, Emily Bellile, Ariane Nguyen, Katie Zarins, Nisha D'Silva, Laura Rozek, Gregory T Wolf, Maureen A Sartor, INSPIRE Trial Clinical Investigators, and Richard Bryan Bell

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Epigenetic Regulation of Immunotherapy Response in Triple-Negative Breast Cancer., Pere Llinàs-Arias, Sandra Íñiguez-Muñoz, Kelly McCann, Leonie Voorwerk, Javier I J Orozco, Miquel Ensenyat-Mendez, Borja Sesé, Maggie L DiNome, and Diego M Marzese

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Axicabtagene Ciloleucel as Second-Line Therapy for Large B-Cell Lymphoma., Frederick L Locke, David B Miklos, Caron A Jacobson, Miguel-Angel Perales, Marie-José Kersten, Olalekan O Oluwole, Armin Ghobadi, Aaron P Rapoport, Joseph McGuirk, John M Pagel, Javier Muñoz, Umar Farooq, Tom van Meerten, Patrick M Reagan, Anna Sureda, Ian W Flinn, Peter Vandenberghe, Kevin W Song, Michael Dickinson, Monique C Minnema, Peter A Riedell, Lori A Leslie, Sridhar Chaganti, Yin Yang, Simone Filosto, Jina Shah, Marco Schupp, Christina To, Paul Cheng, Leo I Gordon, Jason R Westin, and All ZUMA-7 Investigators and Contributing Kite Members

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Caregiver-Oncologist Prognostic Concordance, Caregiver Mastery, and Caregiver Psychological Health and Quality of Life., Kah Poh Loh, Mostafa R Mohamed, Sindhuja Kadambi, Eva Culakova, Huiwen Xu, Allison Magnuson, Marie Flannery, Paul R Duberstein, Ronald M Epstein, Colin McHugh, Ryan D Nipp, Kelly M Trevino, Chandrika Sanapala, Bianca A Hall, Beverly Canin, Arlene A Gayle, Alison Conlin, James Bearden, and Supriya G Mohile

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Characterization of outcomes and practices utilized in the management of internal carotid artery injury not requiring definitive endovascular management., Nyall R London, Abdulaziz AlQahtani, Siani Barbosa, Paolo Castelnuovo, Davide Locatelli, Aldo Stamm, Aaron A Cohen-Gadol, Hussam Elbosraty, Roy Casiano, Jacques Morcos, Ernesto Pasquini, Georgio Frank, Diego Mazzatenta, Garni Barkhoudarian, Chester Griffiths, Daniel Kelly, Christos Georgalas, Trichy N Janakiram, Piero Nicolai, Daniel M Prevedello, and Ricardo L Carrau

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Standard-Dose Pembrolizumab Plus Alternate-Dose Ipilimumab in Advanced Melanoma: KEYNOTE-029 Cohort 1C, a Phase 2 Randomized Study of Two Dosing Schedules., Georgina V Long, Caroline Robert, Marcus O Butler, Felix Couture, Matteo S Carlino, Steven O'Day, Victoria Atkinson, Jonathan S Cebon, Michael P Brown, Stephane Dalle, Andrew G Hill, Geoffrey T Gibney, Steven McCune, Alexander M Menzies, Cuizhen Niu, Nageatte Ibrahim, Blanca Homet Moreno, and Adi Diab

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A CRISPR/Cas9-engineered ARID1A-deficient human gastric cancer organoid model reveals essential and non-essential modes of oncogenic transformation., Yuan-Hung Lo, Kevin S Kolahi, Yuhong Du, Chiung-Ying Chang, Andrey Krokhotin, Ajay Nair, Walter D Sobba, Kasper Karlsson, Sunny J Jones, Teri A Longacre, Amanda T Mah, Bahar Tercan, Alexandra Sockell, Hang Xu, Jose A Seoane, Jin Chen, Ilya Shmulevich, Jonathan S Weissman, Christina Curtis, Andrea Califano, Haian Fu, Gerald R Crabtree, and Calvin J Kuo

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Beyond the Chemotherapy Certificate: Building a Knowledge Base Virtually for Oncology Nursing Practice Across a Health System., Julianne Luttrell, Sarah Sumner, Emy-Lee Marie Anglo Ricafrente, and Marlon G Saria

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Resolution of tissue signatures of therapy response in patients with recurrent GBM treated with neoadjuvant anti-PD1., Yue Lu, Alphonsus H C Ng, Frances E Chow, Richard G Everson, Beth A Helmink, Michael T Tetzlaff, Rohit Thakur, Jennifer A Wargo, Timothy F Cloughesy, Robert M Prins, and James R Heath

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Coinfection of, Samragnyi Madala, Kira MacDougall, Balarama Krishna Surapaneni, Robin Park, Mohit Girotra, and Anup Kasi

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Neoadjuvant immunotherapy is reshaping cancer management across multiple tumour types: The future is now!, Michele Maio, Christian Blank, Andrea Necchi, Anna Maria Di Giacomo, Ramy Ibrahim, Michael Lahn, Bernard A Fox, R Bryan Bell, Giampaolo Tortora, and Alexander M M Eggermont

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A vision of immuno-oncology: the Siena think tank of the Italian network for tumor biotherapy (NIBIT) foundation., Michele Maio, Michael Lahn, Anna Maria Di Giacomo, Alessia Covre, Luana Calabrò, Ramy Ibrahim, Bernard Fox, and Siena Think Tank

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354 Lenvatinib and pembrolizumab in advanced endometrial carcinoma (EC): long-term efficacy and safety update from a phase 1b/2 study, Vicky Makker, Matthew H Taylor, and See full list of authors in comments

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Streamlining brain tumor surgery care during the COVID-19 pandemic: A case-control study., Regin Jay Mallari, Michael B Avery, Alex Corlin, Amalia Eisenberg, Terese C Hammond, Neil A Martin, Garni Barkhoudarian, and Daniel F Kelly

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Endoscopic Endonasal and Supraorbital Removal of Tuberculum Sellae Meningiomas: Anatomic Guides and Operative Nuances for Keyhole Approach Selection., Regin Jay Mallari, Jai Deep Thakur, John H Rhee, Amalia Eisenberg, Howard Krauss, Chester Griffiths, Walavan Sivakumar, Garni Barkhoudarian, and Daniel F Kelly

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Continued proportional age shift of confirmed positive COVID-19 incidence over time to children and young adults: Washington State March-August 2020., Judith Malmgren, Boya Guo, and Henry G Kaplan

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Adjuvant T-DM1 versus trastuzumab in patients with residual invasive disease after neoadjuvant therapy for HER2-positive breast cancer: subgroup analyses from KATHERINE., E P Mamounas, M Untch, M S Mano, C-S Huang, C E Geyer, G von Minckwitz, N Wolmark, X Pivot, S Kuemmel, M P DiGiovanna, B Kaufman, G Kunz, A K Conlin, J C Alcedo, T Kuehn, I Wapnir, A Fontana, J Hackmann, J Polikoff, M Saghatchian, A Brufsky, Y Yang, M Zimovjanova, T Boulet, H Liu, D Tesarowski, L H Lam, C Song, M Smitt, and S Loibl

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Prognostic gene expression signatures of breast cancer are lacking a sensible biological meaning., Kalifa Manjang, Shailesh Tripathi, Olli Yli-Harja, Matthias Dehmer, Galina Glazko, and Frank Emmert-Streib

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Limitations of Explainability for Established Prognostic Biomarkers of Prostate Cancer., Kalifa Manjang, Olli Yli-Harja, Matthias Dehmer, and Frank Emmert-Streib

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A phase I/II study of rovalpituzumab tesirine in delta-like 3-expressing advanced solid tumors., Aaron S Mansfield, David S Hong, Christine L Hann, Anna F Farago, Himisha Beltran, Saiama N Waqar, Andrew E Hendifar, Lowell B Anthony, Matthew H Taylor, Alan H Bryce, Scott T Tagawa, Karl Lewis, Jiaxin Niu, Christine H Chung, James M Cleary, Michael Rossi, Carrianne Ludwig, Ricardo Valenzuela, Yan Luo, and Rahul Aggarwal

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Trifluridine/tipiracil in patients with metastatic gastroesophageal junction cancer: a subgroup analysis from the phase 3 TAGS study., Wasat Mansoor, Hendrik-Tobias Arkenau, Maria Alsina, Kohei Shitara, Peter Thuss-Patience, Sinead Cuffe, Mikhail Dvorkin, David Park, Takayuki Ando, Marc Van Den Eynde, Giordano D Beretta, Alberto Zaniboni, Toshihiko Doi, Josep Tabernero, David H Ilson, Lukas Makris, Karim A Benhadji, and Eric Van Cutsem

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Large polyps: Pearls for the referring and receiving endoscopist., Eric Markarian, Brian M Fung, Mohit Girotra, and James H Tabibian

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Defining Risk Categories for a Significant Decline in Estimated Glomerular Filtration Rate After Robotic Partial Nephrectomy: Implications for Patient Follow-up., Alberto Martini, Ugo Giovanni Falagario, Shivaram Cumarasamy, Ronney Abaza, Daniel D Eun, Akshay Bhandari, James R Porter, Ashok K Hemal, and Ketan K Badani

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Phosphorylation of SMAD3 in immune cells predicts survival of patients with early stage non-small cell lung cancer., Sebastian Marwitz, Carmen Ballesteros-Merino, Shawn M. Jensen, Martin Reck, Christian Kugler, Sven Perner, Daniel Drömann, Torsten Goldmann, and Bernard A Fox

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Durability of Response to Primary Chemoablation of Low-Grade Upper Tract Urothelial Carcinoma Using UGN-101, a Mitomycin-Containing Reverse Thermal Gel: OLYMPUS Trial Final Report., Surena F Matin, Phillip M Pierorazio, Nir Kleinmann, John L Gore, Ahmad Shabsigh, Brian Hu, Karim Chamie, Guilherme Godoy, Scott G Hubosky, Marcelino Rivera, Michael O'Donnell, Marcus Quek, Jay D Raman, John J Knoedler, Douglas Scherr, Christopher Weight, Alon Weizer, Michael Woods, Hristos Kaimakliotis, Angela B Smith, Jennifer M Linehan, Jonathan Coleman, Mitchell R Humphreys, Raymond Pak, David Lifshitz, Michael Verni, Ifat Klein, Marina Konorty, Dalit Strauss-Ayali, Gil Hakim, Elyse Seltzer, Mark Schoenberg, and Seth P Lerner

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Recognizing Unmet Need in the Era of Targeted Therapy for CLL/SLL: "What's Past Is Prologue" (Shakespeare)., Anthony R Mato, Matthew S Davids, Jeff Sharman, Lindsey E Roeker, Neil Kay, Arnon Kater, Kerry Rogers, Meghan C Thompson, Joanna Rhodes, Andre Goy, Alan Skarbnik, Stephen J Schuster, Constantine S Tam, Toby A Eyre, Susan O'Brien, Chadi Nabhan, Nicole Lamanna, Clare Sun, Mazyar Shadman, John M Pagel, Chaitra Ujjani, Danielle Brander, Catherine C Coombs, Nitin Jain, Chan Y Cheah, Jennifer R Brown, John F Seymour, and Jennifer A Woyach

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Pirtobrutinib in relapsed or refractory B-cell malignancies (BRUIN): a phase 1/2 study., Anthony R Mato, Nirav N Shah, Wojciech Jurczak, Chan Y Cheah, John M Pagel, Jennifer A Woyach, Bita Fakhri, Toby A Eyre, Nicole Lamanna, Manish R Patel, Alvaro Alencar, Ewa Lech-Maranda, William G Wierda, Catherine C Coombs, James N Gerson, Paolo Ghia, Steven Le Gouill, David John Lewis, Suchitra Sundaram, Jonathon B Cohen, Ian W Flinn, Constantine S Tam, Minal A Barve, Bryone Kuss, Justin Taylor, Omar Abdel-Wahab, Stephen J Schuster, M Lia Palomba, Katharine L Lewis, Lindsey E Roeker, Matthew S Davids, Xuan Ni Tan, Timothy S Fenske, Johan Wallin, Donald E Tsai, Nora C Ku, Edward Zhu, Jessica Chen, Ming Yin, Binoj Nair, Kevin Ebata, Narasimha Marella, Jennifer R Brown, and Michael Wang

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Vertebral Augmentation of Cancer-Related Spinal Compression Fractures: A Systematic Review and Meta-Analysis., Ryan Mattie, Nick Brar, Jennifer T Tram, Zachary L McCormick, Douglas P Beall, Andrew Fox, and Mikhail Saltychev

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How we approach hemangiomas in infants., Jennifer L R Mayer, Stefanos Intzes, Vikash S Oza, and Francine Blei

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A Microcosm of Disparities in Breast Cancer: Comparison Between a Private Hospital and a Safety-Net County Hospital Within Los Angeles County., Natalie C McClintock, Reed I Ayabe, Ruben D Salas Parra, Amy H Kaji, Javier I Orozco, Diego M Marzese, Estela Samuels, Stacey L Stern, Christine Dauphine, and Junko J Ozao-Choy

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Detection of Human Papillomavirus Integration in Brain Metastases from Oropharyngeal Tumors by Targeted Sequencing., Brian McEllin, Brian C Searle, Lisa DePledge, George Sun, Charles Cobbs, and Mohsen Karimi

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Micro-Loss; Expanding Our Vocabulary to Describe Grief during the Time of Covid., Danielle McLaughlin

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Electronic Charting of Radiation Therapy Planning and Treatment: Report of Task Group 262., James G Mechalakos, Sonja Dieterich, Luis E Fong de Los Santos, Sandra C Fontenla, Joseph Hanley, Vijay A Harwalkar, Linda X Hong, Y Jessica Huang, Grace Gwe-Ya Kim, Susan L Richardson, Steven G Sutlief, Sridhar Yaddanapudi, Sue Merkel, and Mark Parry

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Defining Immunogenic and Radioimmunogenic Tumors., Terry R Medler, Tiffany C Blair, Marka R Crittenden, and Michael J Gough

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Complicated pleural space infections are associated with prolonged recovery and reduced work effectiveness Chest 2021 Annual Meeting Orlando, Florida, AM Meggyesy, Candice L. Wilshire, and See all authors in comments

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Outpatient thoracentesis for pleural effusion following cardiac surgery appears safe with ongoing anticoagulation and antiplatelet use Chest 2021 Annual Meeting Orlando, Florida, AM Meggyesy, Candice L. Wilshire, and See all authors in comments