The Cancer Institute is a leader in cutting-edge treatments. Using a truly multidisciplinary approach, patients have access to advanced diagnostics, minimally invasive surgical interventions, and personalized genomic and immune-oncologic treatment options. Our team of cancer specialists – many of whom completed fellowships and specialty training at prestigious academic centers – offers comprehensive services for individuals with a cancer diagnosis.

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Submissions from 2019

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An Inflammatory Landscape for Preoperative Neurologic Deficits in Glioblastoma., Amal Katrib, Hyun-Hwan Jeong, Nina L Fransen, Kristin S Henzel, and Jeremy A Miller

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Safety and Efficacy of Durvalumab and Tremelimumab Alone or in Combination in Patients with Advanced Gastric and Gastroesophageal Junction Adenocarcinoma., Ronan J Kelly, Jeeyun Lee, Yung-Jue Bang, Khaldoun Almhanna, Mariela Blum Murphy, Daniel V T Catenacci, Hyun Cheol Chung, Zev A Wainberg, Michael K Gibson, Keun-Wook Lee, Johanna C Bendell, Crystal S Denlinger, Cheng Ean Chee, Takeshi Omori, Rom Leidner, Heinz-Josef Lenz, Yee Chao, Marlon C Rebelatto, Philip Brohawn, Peng He, Jennifer McDevitt, Siddharth Sheth, Judson M Englert, and Geoffrey Y Ku

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A phase 2 trial with ABI-009 (nab-sirolimus) as single-agent and combinations in recurrent high-grade glioma (rHGG) and in newly diagnosed glioblastoma (ndGBM), Santosh Kesari, Tiffany Jaurez, Jose Carrillo, Judy D Truong, Minhdan Nguyen, Annie Heng, Jaya Mini Gill, Hanh Nguyen, Natsuko Nomura, Berta Grigorian, Shihie Hou, Anita Schmid, and Neil Desai

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Neoadjuvant chemotherapy in patients with advanced endometrial cancer., Olivia R Khouri, Melissa K Frey, Fernanda Musa, Franco Muggia, Jessica Lee, Leslie Boyd, John P Curtin, and Bhavana Pothuri

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Radioembolization with Yttrium-90 Microspheres for the Treatment of Liver Metastases of Pancreatic Adenocarcinoma: A Multicenter Analysis., Alexander Y Kim, Shelby Frantz, Jayson Brower, and Nabeel Akhter

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"Chemotherapy-periodized" Exercise to Accommodate for Cyclical Variation in Fatigue., Amy A Kirkham, Kelcey A Bland, David S Zucker, Joshua Bovard, Tamara Shenkier, Donald C McKenzie, Margot K Davis, Karen A Gelmon, and Kristin L Campbell

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Long-term Outcomes of Stereotactic Body Radiotherapy for Low-Risk and Intermediate-Risk Prostate Cancer., Amar U Kishan, Audrey Dang, Alan J Katz, Constantine A Mantz, Sean P Collins, Nima Aghdam, Fang-I Chu, Irving D Kaplan, Limor Appelbaum, Donald B Fuller, Robert M Meier, D Andrew Loblaw, Patrick Cheung, Huong T Pham, Narek Shaverdian, Naomi Jiang, Ye Yuan, Hilary Bagshaw, Nicolas Prionas, Mark K Buyyounouski, Daniel E Spratt, Patrick W Linson, Robert L Hong, Nicholas G Nickols, Michael L Steinberg, Patrick A Kupelian, and Christopher R King

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Completion lymphadenectomy for a positive sentinel node biopsy in melanoma patients is not associated with a survival benefit., Nicholas D Klemen, Gang Han, Stanley P Leong, Mohammed Kashani-Sabet, John Vetto, Richard White, Schlomo Schneebaum, Barbara Pockaj, Nicola Mozzillo, Kim Charney, Harald Hoekstra, Vernon K Sondak, Jane L Messina, Jonathan S Zager, and Dale Han

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Completion lymphadenectomy for a positive sentinel node biopsy in melanoma patients is not associated with a survival benefit., Nicholas D Klemen, Gang Han, Stanley P Leong, Mohammed Kashani-Sabet, John Vetto, Richard White, Schlomo Schneebaum, Barbara Pockaj, Nicola Mozzillo, Kim Charney, Harald Hoekstra, Vernon K Sondak, Jane L Messina, Jonathan S Zager, and Dale Han

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Targeted Intraoperative Radiotherapy During Breast-conserving Surgery for Breast Cancer in Patients After Implant Augmentation., Hans-Christian Kolberg, Valery Uhl, Samuele Massarut, Dennis R Holmes, Cornelia Kolberg-Liedtke, Erica Whineray Kelly, György Lövey, and Jayant S Vaidya

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What's New in Ovarian Cancer, Jessica L. Kozuki

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Cytomegalovirus promotes murine glioblastoma growth via pericyte recruitment and angiogenesis., Harald Krenzlin, Prajna Behera, Viola Lorenz, Carmela Passaro, Mykola Zdioruk, Michal O Nowicki, Korneel Grauwet, Hong Zhang, Magdalena Skubal, Hirotaka Ito, Rachel Zane, Michael Gutknecht, Marion B Griessl, Franz Ricklefs, Lai Ding, Sharon Peled, Arun Rooj, C David James, Charles S Cobbs, Charles H Cook, E Antonio Chiocca, and Sean E Lawler

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Phase II Open-Label Study of Pembrolizumab in Treatment-Refractory, Microsatellite Instability-High/Mismatch Repair-Deficient Metastatic Colorectal Cancer: KEYNOTE-164., Dung T Le, Tae Won Kim, Eric Van Cutsem, Ravit Geva, Dirk Jäger, Hiroki Hara, Matthew Burge, Bert O'Neil, Petr Kavan, Takayuki Yoshino, Rosine Guimbaud, Hiroya Taniguchi, Elena Elez, Salah-Eddin Al-Batran, Patrick M Boland, Todd S Crocenzi, Chloe E Atreya, Yi Cui, Tong Dai, Patricia Marinello, Luis A Diaz, and Thierry André

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Results from a Phase IIb, Randomized, Multicenter Study of GVAX Pancreas and CRS-207 Compared with Chemotherapy in Adults with Previously Treated Metastatic Pancreatic Adenocarcinoma (ECLIPSE Study)., Dung T Le, Vincent J Picozzi, Andrew H Ko, Zev A Wainberg, Hedy Kindler, Andrea Wang-Gillam, Paul Oberstein, Michael A Morse, Herbert J Zeh, Colin Weekes, Tony Reid, Erkut Borazanci, Todd S Crocenzi, Noelle K LoConte, Benjamin Musher, Dan Laheru, Aimee Murphy, Chan Whiting, Nitya Nair, Amanda Enstrom, Sandy Ferber, Dirk G Brockstedt, and Elizabeth M Jaffee

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Characterizing the cancer-associated microbiome with small RNA sequencing data., Wei-Hao Lee, Kai-Pu Chen, Kai Wang, Hsuan-Cheng Huang, and Hsueh-Fen Juan

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The Impact of Gravity vs Suction-driven Therapeutic Thoracentesis on Pressure-related Complications: The GRAVITAS Multicenter Randomized Controlled Trial., Robert J Lentz, Samira Shojaee, Horiana B Grosu, Otis B Rickman, Lance Roller, Jasleen K Pannu, Zachary S DePew, Labib G Debiane, Joseph C Cicenia, Jason Akulian, Charla Walston, Trinidad M Sanchez, Kevin R Davidson, Nikhil Jagan, Sahar Ahmad, Christopher R Gilbert, John T Huggins, Heidi Chen, Richard W Light, Lonny Yarmus, David Feller-Kopman, Hans Lee, Najib M Rahman, and Fabien Maldonado

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Duration of Oxaliplatin-Containing Adjuvant Therapy for Stage III Colon Cancer: ASCO Clinical Practice Guideline., Christopher Lieu, Erin B Kennedy, Emily Bergsland, Jordan Berlin, Thomas J George, Sharlene Gill, Philip J Gold, Alex Hantel, Lee Jones, Najjia Mahmoud, Jeffrey Meyerhardt, Arden M Morris, Erika Ruíz-García, Y Nancy You, and Nancy Baxter

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Prospective Molecular Profiling of Circulating Tumor Cells from Patients with Melanoma Receiving Combinatorial Immunotherapy., Selena Y Lin, Shu-Ching Chang, Stella Lam, Romela Irene Ramos, Kevin Tran, Shuichi Ohe, Matthew P Salomon, Ali Asgar S Bhagat, Chwee Teck Lim, Trevan D Fischer, Leland J Foshag, Christine L Boley, Steven J O'Day, and Dave S B Hoon

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Evaluation of Surgical Resection Goal and Its Relationship to Extent of Resection and Patient Outcomes in a Multicenter Prospective Study of Patients With Surgically Treated, Nonfunctioning Pituitary Adenomas: A Case Series., Andrew S Little, Michael R Chicoine, Daniel F Kelly, Christina E Sarris, Michael A Mooney, William L White, Paul A Gardner, Juan C Fernandez-Miranda, Garni Barkhoudarian, James P Chandler, Daniel M Prevedello, Brandon D Liebelt, John Sfondouris, and Marc R Mayberg

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Epigenetic hypomethylation and upregulation of GD3s in triple negative breast cancer., Wan Li, Xiangjin Zheng, Liwen Ren, Weiqi Fu, Jinyi Liu, Jun Xv, Shiwei Liu, Jinhua Wang, and Guanhua Du

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Genetic interaction analysis among oncogenesis-related genes revealed novel genes and networks in lung cancer development., Yafang Li, Xiangjun Xiao, Yohan Bossé, Olga Gorlova, Ivan Gorlov, Younghun Han, Jinyoung Byun, Natasha Leighl, Jakob S Johansen, Matt Barnett, Chu Chen, Gary E Goodman, Angela Cox, Fiona Taylor, Penella Woll, H Erich Wichmann, Judith Manz, Thomas Muley, Angela Risch, Albert Rosenberger, Jiali Han, Katherine Siminovitch, Susanne M Arnold, Eric B Haura, Ciprian Bolca, Ivana Holcatova, Vladimir Janout, Milica Kontic, Jolanta Lissowska, Anush Mukeria, Simona Ognjanovic, Tadeusz M Orlowski, Ghislaine Scelo, Beata Swiatkowska, David Zaridze, Per Bakke, Vidar Skaug, Shanbeh Zienolddiny, Eric J Duell, Lesley M Butler, Richard Houlston, María Soler Artigas, Kjell Grankvist, Mikael Johansson, Frances A Shepherd, Michael W Marcus, Hans Brunnström, Jonas Manjer, Olle Melander, David C Muller, Kim Overvad, Antonia Trichopoulou, Rosario Tumino, Geoffrey Liu, Stig E Bojesen, Xifeng Wu, Loic Le Marchand, Demetrios Albanes, Heike Bickeböller, Melinda C Aldrich, William S Bush, Adonina Tardon, Gad Rennert, M Dawn Teare, John K Field, Lambertus A Kiemeney, Philip Lazarus, Aage Haugen, Stephen Lam, Matthew B Schabath, Angeline S Andrew, Pier Alberto Bertazzi, Angela C Pesatori, David C Christiani, Neil Caporaso, Mattias Johansson, James D McKay, Paul Brennan, Rayjean J Hung, and Christopher I Amos

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Liquid biopsy-based single-cell metabolic phenotyping of lung cancer patients for informative diagnostics., Ziming Li, Zhuo Wang, Yin Tang, Xiang Lu, Jie Chen, Yu Dong, Baojun Wu, Chunying Wang, Liu Yang, Zhili Guo, Min Xue, Shun Lu, Wei Wei, and Qihui Shi

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Engagement in HIV Care and Access to Cancer Treatment Among Patients With HIV-Associated Malignancies in Uganda., Daniel H Low, Warren Phipps, Jackson Orem, Corey Casper, and Rachel A Bender Ignacio

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Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal Cancer., Winifred Lo, Maria Parkhurst, Paul F Robbins, Eric Tran, Yong-Chen Lu, Li Jia, Jared J Gartner, Anna Pasetto, Drew Deniger, Parisa Malekzadeh, Thomas E Shelton, Todd Prickett, Satyajit Ray, Scott Kivitz, Biman C Paria, Isaac Kriley, David S Schrump, and Steven A Rosenberg

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Biological intratumoral therapy for the high-grade glioma part I: intratumoral delivery and immunotoxins., Joshua Loya, Charlie Zhang, Emily J Cox, Achal Singh Achrol, and Santosh Kesari

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Biological intratumoral therapy for the high-grade glioma part II: vector- and cell-based therapies and radioimmunotherapy., Joshua Loya, Charlie Zhang, Emily J Cox, Achal Singh Achrol, and Santosh Kesari

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Clinical Documentation and Patient Care Using Artificial Intelligence in Radiation Oncology., Join Y Luh, Reid F Thompson, and Steven Lin

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Introduction: the 12th Biennial Rivkin Center Ovarian Cancer Research Symposium., Nita J Maihle, Douglas A Levine, Kiran Dhillon, and Deborah Kay Armstrong

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Addressing current challenges and future directions in immuno-oncology: expert perspectives from the 2017 NIBIT Foundation Think Tank, Siena, Italy., Michele Maio, George Coukos, Soldano Ferrone, Bernard A Fox, Wolf H Fridman, Patrick L Garcia, Michael Lahn, Olivier Provendier, Vincenzo Russo, Dominik Rüttinger, Aiman Shalabi, Zlatko Trajanoski, Jean Viallet, Jedd D Wolchok, and Ramy Ibrahim

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Neoantigen screening identifies broad TP53 mutant immunogenicity in patients with epithelial cancers., Parisa Malekzadeh, Anna Pasetto, Paul F Robbins, Maria R Parkhurst, Biman C Paria, Li Jia, Jared J Gartner, Victoria Hill, Zhiya Yu, Nicholas P Restifo, Abraham Sachs, Eric Tran, Winifred Lo, Robert Pt Somerville, Steven A Rosenberg, and Drew C Deniger

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Neoantigen screening identifies broad TP53 mutant immunogenicity in patients with epithelial cancers., Parisa Malekzadeh, Anna Pasetto, Paul F Robbins, Maria R Parkhurst, Biman C Paria, Li Jia, Jared J Gartner, Victoria Hill, Zhiya Yu, Nicholas P Restifo, Abraham Sachs, Eric Tran, Winifred Lo, Robert Pt Somerville, Steven A Rosenberg, and Drew C Deniger

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Metastatic breast cancer survival improvement restricted by regional disparity: Surveillance, Epidemiology, and End Results and institutional analysis: 1990 to 2011., Judith A Malmgren, Gregory S Calip, Mary K Atwood, Musa Mayer, and Henry G Kaplan

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Consensus-Building efforts to identify best tools for screening and assessment for supportive services in oncology., Timothy F Marshall, Catherine M Alfano, Alix G Sleight, Richard P Moser, David S Zucker, Elise L Rice, Julie K Silver, Vishwa S Raj, Jack B Fu, Lynne S Padgett, Kathleen Doyle Lyons, Mary Vining Radomski, Raymond McKenna, and Mackenzi Pergolotti

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Defining Risk Categories for a Significant Decline in Estimated Glomerular Filtration Rate After Robotic Partial Nephrectomy: Implications for Patient Follow-up., Alberto Martini, Ugo Giovanni Falagario, Shivaram Cumarasamy, Ronney Abaza, Daniel D Eun, Akshay Bhandari, James R Porter, Ashok K Hemal, and Ketan K Badani

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Efficacy of Therapies Following Venetoclax Discontinuation in CLL: Focus on B-Cell Receptor Signal Transduction Inhibitors and Cellular Therapies, Anthony R. Mato, Neil Bailey, and See full list of authors in comments

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A retrospective comparison of venetoclax alone or in combination with an anti-CD20 monoclonal antibody in R/R CLL., Anthony R Mato, Lindsey E Roeker, Toby A Eyre, Chadi Nabhan, Nicole Lamanna, Brian T Hill, Danielle M Brander, Paul M Barr, Frederick Lansigan, Bruce D Cheson, Arun K Singavi, Maryam Sarraf Yazdy, Nirav N Shah, John N Allan, Erica B Bhavsar, Joanna Rhodes, Kaitlin Kennard, Stephen J Schuster, AnnaLynn M Williams, Alan P Skarbnik, Andre H Goy, Julie M Goodfriend, Colleen Dorsey, Catherine C Coombs, Hande Tuncer, Chaitra S Ujjani, Ryan Jacobs, Allison M Winter, John M Pagel, Neil Bailey, Anna Schuh, Mazyar Shadman, Andrea Sitlinger, Hanna Weissbrot, Sivraj Muralikrishnan, Andrew Zelenetz, Amy A Kirkwood, and Christopher P Fox

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Mitochondrial stress triggers a pro-survival response through epigenetic modifications of nuclear DNA., Lía Mayorga, Betiana N Salassa, Diego M Marzese, Mariana A Loos, Hernán D Eiroa, Fabiana Lubieniecki, Clara García Samartino, Patricia S Romano, and María Roqué

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Activating the Nucleic Acid-Sensing Machinery for Anticancer Immunity., Terry R Medler, Jaina M Patel, Alejandro Alice, Jason R Baird, Hong-Ming Hu, and Michael J Gough

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A Phase Ib study of isatuximab plus pomalidomide/dexamethasone in relapsed/refractory multiple myeloma., Joseph Mikhael, Paul Richardson, Saad Z Usmani, Noopur Raje, William Bensinger, Chatchada Karanes, Frank Campana, Dheepak Kanagavel, Franck Dubin, Qianying Liu, Dorothée Semiond, and Kenneth Anderson

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Terminal Bleeding in Angiosarcoma., Jaya Mini Gill, Brian Madden, Janice Frost, Rebecca Crane-Okada, Robert L Hulsman, Kristen Elliott, and Marlon G Saria

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Robotic retroperitoneal lymph node dissection for testicular cancer: feasibility and latest outcomes., Harsha R Mittakanti and James R Porter

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MITF has a central role in regulating starvation-induced autophagy in melanoma., Katrin Möller, Sara Sigurbjornsdottir, Asgeir O Arnthorsson, Vivian Pogenberg, Ramile Dilshat, Valerie Fock, Solveig H Brynjolfsdottir, Christian Bindesboll, Margret Bessadottir, Helga M Ogmundsdottir, Anne Simonsen, Lionel Larue, Matthias Wilmanns, Vesteinn Thorsson, Eirikur Steingrimsson, and Margret H Ogmundsdottir

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Meningioma-like Tumor of the Skin Revisited: A Distinct CD34+ Dermal Tumor With an Expanded Histologic Spectrum., Carlos Monteagudo, Ana I Jiménez, Angeles Arnandis, and Ronald J Barr

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Pronounced clinical response following the oncolytic vaccinia virus GL-ONC1 and chemotherapy in a heavily pretreated ovarian cancer patient., Kristina M Mori, Peter D Giuliano, Katrina L Lopez, Monica M King, Randy Bohart, and Bram H Goldstein

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Pronounced clinical response following the oncolytic vaccinia virus GL-ONC1 and chemotherapy in a heavily pretreated ovarian cancer patient., Kristina M Mori, Peter D Giuliano, Katrina L Lopez, Monica M King, Randy Bohart, and Bram H Goldstein

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Recent Progress in the Theranostics Application of Nanomedicine in Lung Cancer., Anubhab Mukherjee, Manash Paul, and Sudip Mukherjee

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Lipid-polymer hybrid nanoparticles as a next-generation drug delivery platform: state of the art, emerging technologies, and perspectives., Anubhab Mukherjee, Ariana K Waters, Pranav Kalyan, Achal Singh Achrol, Santosh Kesari, and Venkata Yenugonda

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A feasibility study of the Nativis Voyager, Michael Murphy, Anthony Dowling, Christopher Thien, Emma Priest, Donna Morgan Murray, and Santosh Kesari

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Anti-PD-1 monoclonal antibody MEDI0680 in a phase I study of patients with advanced solid malignancies., Aung Naing, Jeffrey Infante, Sanjay Goel, Howard Burris, Chelsea Black, Shannon Marshall, Ikbel Achour, Susannah Barbee, Rena May, Chris Morehouse, Kristen Pollizzi, Xuyang Song, Keith Steele, Nairouz Elgeioushi, Farzana Walcott, Joyson Karakunnel, Patricia LoRusso, Amy Weise, Joseph Eder, Brendan Curti, and Michael Oberst

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Impact of Effective Systemic Therapy on Metastasectomy in Stage IV Melanoma: A Matched-Pair Analysis., Daniel W Nelson, Trevan D Fischer, Amanda N Graff-Baker, Ahmed Dehal, Stacey L Stern, Anton J Bilchik, and Mark B Faries

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Expert Consensus Statement on Optimal Approach to Lobectomy for Non-Small Cell Lung Cancer., Calvin S H Ng, John K MacDonald, Sebastien Gilbert, Ali Z Khan, Young T Kim, Brian E Louie, M Blair Marshall, Ricardo S Santos, Marco Scarci, Yaron Shargal, and Hiran C Fernando

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Optimal Approach to Lobectomy for Non-Small Cell Lung Cancer: Systemic Review and Meta-Analysis., Calvin S H Ng, John K MacDonald, Sebastien Gilbert, Ali Z Khan, Young T Kim, Brian E Louie, M Blair Marshall, Ricardo S Santos, Marco Scarci, Yaron Shargal, and Hiran C Fernando

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Macrophage fatty acid oxidation inhibits atherosclerosis progression., Mitsunori Nomura, Jie Liu, Zu-Xi Yu, Tomoko Yamazaki, Ye Yan, Hiroyuki Kawagishi, Ilsa I Rovira, Chengyu Liu, Michael J Wolfgang, Yoh-Suke Mukouyama, and Toren Finkel

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A phase II randomized, double-blind trial of a polyvalent Vaccine-KLH conjugate (NSC 748933 IND# 14384) + OPT-821 versus OPT-821 in patients with epithelial ovarian, fallopian tube, or peritoneal cancer who are in second or third complete remission: An NRG Oncology/GOG study., Roisin E O'Cearbhaill, Wei Deng, Lee-May Chen, Joseph A Lucci, Kian Behbakht, Nick M Spirtos, Carolyn Y Muller, Benedict B Benigno, Matthew A Powell, Emily Berry, Krishnansu S Tewari, Parviz Hanjani, Heather A Lankes, Carol Aghajanian, and Paul J Sabbatini

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Clinical Implications of Transcriptomic Changes After Neoadjuvant Chemotherapy in Patients with Triple-Negative Breast Cancer., Javier I Orozco, Janie Grumley, Chikako Matsuba, Ayla O Manughian-Peter, Shu-Ching Chang, Grace Chang, Francisco E Gago, Matthew P Salomon, and Diego M Marzese

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Epigenetic Classifiers for Precision Diagnosis of Brain Tumors., Javier I Orozco, Ayla O Manughian-Peter, Matthew P Salomon, and Diego M Marzese

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A phase Ib study of pre-operative, locoregional IRX-2 cytokine immunotherapy to prime immune responses in patients with early stage breast cancer., David B Page, Joanna Pucilowska, Katherine G Sanchez, Alison K Conlin, Anupama Acheson, Kelly S Perlewitz, James H Imatani, Shagheyegh Aliabadi-Wahle, Nikki Moxon, Staci Mellinger, Amanda Y Seino, Maritza Martel, Yaping Wu, Zhaoyu Sun, William L. Redmond, Valerie Conrad, Venkatesh Rajamanickam, Dottie Waddell, Deborah Laxague, Monil Shah, Shu-Ching Chang, and Walter Urba

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Real-world treatment patterns and adverse events in metastatic renal cell carcinoma from a large US claims database., Sumanta Pal, Jun Gong, Shivani K Mhatre, Shih-Wen Lin, Andy Surinach, Sarika Ogale, Rini Vohra, Herschel Wallen, and Daniel George

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Preoperative stimulation of resolution and inflammation blockade eradicates micrometastases., Dipak Panigrahy, Allison Gartung, Jun Yang, Haixia Yang, Molly M Gilligan, Megan L Sulciner, Swati S Bhasin, Diane R Bielenberg, Jaimie Chang, Birgitta A Schmidt, Julia Piwowarski, Anna Fishbein, Dulce Soler-Ferran, Matthew A Sparks, Steven J Staffa, Vidula Sukhatme, Bruce D Hammock, Mark W Kieran, Sui Huang, Manoj Bhasin, Charles N Serhan, and Vikas P Sukhatme

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First-In-Human Study of Cemiplimab Alone or In Combination with Radiotherapy and/or Low Dose Cyclophosphamide in Patients with Advanced Malignancies., Kyriakos P Papadopoulos, Melissa L Johnson, Albert Craig Lockhart, Kathleen N Moore, Gerald S Falchook, Silvia C Formenti, Aung Naing, Richard D Carvajal, Lee S Rosen, Glen J Weiss, Rom Leidner, Jingjin Li, Anne Paccaly, Minjie Feng, Elizabeth Stankevich, Israel Lowy, Matthew G Fury, and Marka R Crittenden

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Unique Neoantigens Arise from Somatic Mutations in Patients with Gastrointestinal Cancers., Maria R Parkhurst, Paul F Robbins, Eric Tran, Todd D Prickett, Jared J Gartner, Li Jia, Gabriel Ivey, Yong F Li, Mona El-Gamil, Almin Lalani, Jessica S Crystal, Abraham Sachs, Eric Groh, Satyajit Ray, Lien T Ngo, Scott Kivitz, Anna Pasetto, Rami Yossef, Frank J Lowery, Stephanie L Goff, Winifred Lo, Gal Cafri, Drew C Deniger, Parisa Malekzadeh, Mojgan Ahmadzadeh, John R Wunderlich, Robert P T Somerville, and Steven A Rosenberg

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Peritumoral administration of DRibbles-pulsed antigen-presenting cells enhances the antitumor efficacy of anti-GITR and anti-PD-1 antibodies via an antigen presenting independent mechanism., Jaina M Patel, Zhihua Cui, Zhi-Fa Wen, Catherine T Dinh, and Hong-Ming Hu

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Duvelisib for CLL/SLL and Follicular Non-Hodgkin Lymphoma., Krish Patel, Alexey Danilov, and John M Pagel

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Duvelisib for CLL/SLL and follicular non-Hodgkin lymphoma., Krish Patel, Alexey V Danilov, and John M Pagel

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Exploring a Future for PI3K Inhibitors in Chronic Lymphocytic Leukemia., Krish Patel and John M Pagel

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Impact of dosing frequency (once daily or twice daily) on patient adherence to oral targeted therapies for hematologic malignancies: a retrospective cohort study among managed care enrollees., Krish Patel, Vinjamuri S Sudhir, Shaum Kabadi, Joanna C Huang, Sanchita Porwal, Kushan Thakkar, and John M Pagel

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Analysis of cell-free circulating tumor DNA in 419 patients with glioblastoma and other primary brain tumors., David E Piccioni, Achal Singh Achrol, Lesli A Kiedrowski, Kimberly C Banks, Najee Boucher, Garni Barkhoudarian, Daniel F Kelly, Tiffany Juarez, Richard B Lanman, Victoria M Raymond, Minhdan Nguyen, Judy D Truong, Annie Heng, Jaya Mini Gill, Marlon G Saria, Sandeep C Pingle, and Santosh Kesari

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Comprehensive Genomic Tumor Profiling, Brian D. Piening

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Glioblastoma Mimicking Viral Encephalitis Responds to Acyclovir: A Case Series and Literature Review., Keenan J Piper, Haidn Foster, Brandon Gabel, Burt Nabors, and Charles Cobbs

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Blockade of TGF-β signaling to enhance the antitumor response is accompanied by dysregulation of the functional activity of CD4, Magdalena J Polanczyk, Edwin Walker, Daniel Haley, Bella S Guerrouahen, and Emmanuel T Akporiaye

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A Pan-Cancer Approach to Predict Responsiveness to Immune Checkpoint Inhibitors by Machine Learning., Maurizio Polano, Marco Chierici, Michele Dal Bo, Davide Gentilini, Federica Di Cintio, Lorena Baboci, David L Gibbs, Cesare Furlanello, and Giuseppe Toffoli

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OX40 Agonist Tumor Immunotherapy Does Not Impact Regulatory T Cell Suppressive Function., Fanny Polesso, Minhaz Sarker, Andrew D Weinberg, Susan E Murray, and Amy E Moran

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OX40 Agonist Tumor Immunotherapy Does Not Impact Regulatory T Cell Suppressive Function., Fanny Polesso, Minhaz Sarker, Andrew D Weinberg, Susan E Murray, and Amy E Moran

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Recurrence After Robotic Retroperitoneal Lymph Node Dissection Raises More Questions than Answers., James R Porter, Scott Eggener, Erik Castle, and Phillip Pierorazio

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Regeneration Enhances Metastasis: A Novel Role for Neurovascular Signaling in Promoting Melanoma Brain Metastasis., Roshini Prakash, Sivan Izraely, Nikita S Thareja, Rex H Lee, Maya Rappaport, Riki Kawaguchi, Orit Sagi-Assif, Shlomit Ben-Menachem, Tsipi Meshel, Michal Machnicki, Shuichi Ohe, Dave S B Hoon, Giovanni Coppola, Isaac P Witz, and S Thomas Carmichael

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Immunological Complexity of the Prostate Cancer Microenvironment Influences the Response to Immunotherapy., Nataliya Prokhnevska, Dana A Emerson, Haydn T Kissick, and William L. Redmond

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Upregulation of Ganglioside GD3 Synthase (ST8SIA1) Promotes Distant Organ Metastasis In Melanoma Patients, Irene Ramos

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Renal Considerations in the Oncology Patient, Sridhar K. Reddy

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Non-TB Mycobacterial Infection-Bronchiectasis Nexus., Jerome M Reich

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Non-TB Mycobacterial Infection-Bronchiectasis Nexus., Jerome M Reich

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Two Radiographic Features Favoring Radiation Pneumonitis in the Differential Diagnosis., Jerome M Reich

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Current Controversies in Cardiothoracic Imaging: Low-dose Computerized Tomographic Overdiagnosis of Lung Cancer is Substantial; Its Consequences are Underappreciated-Point., Jerome M Reich and Jong S Kim

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Earlier Diagnosis Not Self-Evidently Beneficial: Natural History of Subcentimeter Lung Cancers., Jerome M Reich and Jong S Kim

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Birds of a Feather? Genetic Counseling, Genetic Testing, and Humanism., Robert Resta

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INTRODUCTION TO EXPLORING THE EXOME SPECIAL ISSUE., Robert Resta, Jennifer Sullivan, and Allyn McConkie-Rosell

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Provider Attitudes and Practice Patterns for Direct-Acting Antiviral Therapy for Patients with Hepatocellular Carcinoma., Nicole E Rich, Ju Dong Yang, Ponni V Perumalswami, Naim Alkhouri, Whitney Jackson, Neehar D Parikh, Neil Mehta, Reena Salgia, Andres Duarte-Rojo, Laura Kulik, Mina Rakoski, Adnan Said, Omobonike Oloruntoba, George N Ioannou, Maarouf A Hoteit, Andrew M Moon, Amol S Rangnekar, Sheila L Eswaran, Elizabeth Zheng, Janice H Jou, James Hanje, Anjana Pillai, Ruben Hernaez, Robert Wong, Steven Scaglione, Hrishikesh Samant, Devika Kapuria, Shaun Chandna, Russell Rosenblatt, Veeral Ajmera, Catherine Frenette, Sanjaya K Satapathy, Parvez Mantry, Prasun Jalal, Binu V John, Oren K Fix, Michael Leise, Christina C Lindenmeyer, Avegail Flores, Nayan Patel, Z Gordon Jiang, Nyan Latt, Renumathy Dhanasekaran, Mobolaji Odewole, Sofia Kagan, Jorge A Marrero, and Amit G Singal

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Phase Ib with expansion study of olaparib plus weekly (Metronomic) carboplatin and paclitaxel in relapsed ovarian cancer patients., Saul Eugene Rivkin, James Moon, Desiree S Iriarte, Erik Bailey, Heather L Sloan, Gary E Goodman, Amy E BonDurant, Dan Velijovich, Tanya Wahl, Peter Jiang, Chirag A Shah, Charles Drescher, MF Fer, Henry G Kaplan, and Erin D Ellis

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Tumor Lysis, Adverse Events, and Dose Adjustments in 297 Venetoclax-Treated CLL Patient in Routine Clinical Practice., Lindsey E Roeker, Christopher P Fox, Toby A Eyre, Danielle M Brander, John N Allan, Stephen J Schuster, Chadi Nabhan, Brian T Hill, Nirav N Shah, Frederick Lansigan, Maryam Yazdy, Bruce D Cheson, Nicole Lamanna, Arun K Singavi, Catherine C Coombs, Paul M Barr, Alan P Skarbnik, Mazyar Shadman, Chaitra S Ujjani, Hande H Tuncer, Allison M Winter, Joanna Rhodes, Colleen Dorsey, Hannah Morse, Charlene Kabel, John M Pagel, Annalynn M Williams, Ryan Jacobs, Andre Goy, Sivraj Muralikrishnan, Laurie Pearson, Andrea Sitlinger, Neil Bailey, Anna Schuh, Amy A Kirkwood, and Anthony R Mato

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Nomogram for Predicting Individual Survival After Recurrence of Advanced-Stage, High-Grade Ovarian Carcinoma., Peter G Rose, James J Java, Ritu Salani, Melissa A Geller, Angeles Alvarez Secord, Krishnansu S Tewari, David P Bender, David G Mutch, Michael L Friedlander, Linda Van Le, Michael W Method, Chad A Hamilton, Roger B Lee, Robert M Wenham, Saketh R Guntupalli, Maurie Markman, Franco M Muggia, Deborah K Armstrong, Michael A Bookman, Robert A Burger, and Larry J Copeland

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Cervical cancer in Tanzania: A systematic review of current challenges in six domains., Ava S Runge, Megan E Bernstein, Alexa N Lucas, and Krishnansu S Tewari

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Immunotherapy Toxicities., Katherine Sanchez, David B Page, and Walter Urba

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Phase I/II trial of nano-camptothecin CRLX101 with capecitabine and radiotherapy as neoadjuvant treatment for locally advanced rectal cancer., Hanna K Sanoff, Dominic H Moon, Dominic T Moore, Jeremiah Boles, Courtney Bui, William Blackstock, Bert H O'Neil, Somasundaram Subramaniam, Autumn J McRee, Cheryl Carlson, Michael S Lee, Joel E Tepper, and Andrew Z Wang

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ASO Author Reflections: The Changing Landscape for Industry Support to Surgical Oncologists., Juan A Santamaria-Barria and Anton J Bilchik

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Changing Trends in Industry Funding for Surgical Oncologists., Juan A Santamaria-Barria, Stacey L Stern, Adam Khader, Mary Garland-Kledzik, Anthony J Scholer, Trevan D Fischer, and Anton J Bilchik

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Hospitalized patients quantify verbal pain intensity descriptors: methodological issues and values for 26 descriptors., Judith M Schlaeger, Kevin C Cain, Erin K Myklebust, Keesha L Powell-Roach, Brenda W Dyal, and Diana J Wilkie

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Developing "Nurse AMIE": A tablet-based supportive care intervention for women with metastatic breast cancer., Kathryn H Schmitz, Xiaochen Zhang, Renate Winkels, Erica Schleicher, Katlynn Mathis, Shawna Doerksen, Leah Cream, Jennifer Rosenberg, Rena Kass, Michelle Farnan, Patricia Halpin-Murphy, Robin Suess, David S Zucker, and Michael Hayes

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Downregulation of CENPF Remodels Prostate Cancer Cells and Alters Cellular Metabolism., Muhammad Shahid, Minhyung Kim, Min Young Lee, Austin Yeon, Sungyong You, Hyung L Kim, and Jayoung Kim

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Downregulation of CENPF Remodels Prostate Cancer Cells and Alters Cellular Metabolism., Muhammad Shahid, Minhyung Kim, Min Young Lee, Austin Yeon, Sungyong You, Hyung L Kim, and Jayoung Kim

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Glioblastoma: Biology, Diagnosis, and Treatment, Akanksha Sharma, Maciej M. Mrugala, and Jan Buckner

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ELEVATE TN: Phase 3 Study of Acalabrutinib Combined with Obinutuzumab (O) or Alone Vs O Plus Chlorambucil (Clb) in Patients (Pts) with Treatment-Naive Chronic Lymphocytic Leukemia (CLL)., Jeff P Sharman, Versha Banerji, Laura Maria Fogliatto, Yair Herishanu, Talha Munir, Renata Walewska, George Follows, Karin Karlsson, Paolo Ghia, Gillian Corbett, Patricia Walker, Miklos Egyed, Wojciech Jurczak, Gilles Salles, Ann Janssens, Florence Cymbalista, William G Wierda, Steven Coutre, John M Pagel, Alan Skarbnik, Manali Kamdar, Jennifer Woyach, Raquel Izumi, Veerendra Munugalavadla, Priti Patel, Min Hui Wang, Sofia Wong, and John C Byrd