The Cancer Institute is a leader in cutting-edge treatments. Using a truly multidisciplinary approach, patients have access to advanced diagnostics, minimally invasive surgical interventions, and personalized genomic and immune-oncologic treatment options. Our team of cancer specialists – many of whom completed fellowships and specialty training at prestigious academic centers – offers comprehensive services for individuals with a cancer diagnosis.

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Submissions from 2019

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Epigenetic Classifiers for Precision Diagnosis of Brain Tumors., Javier I Orozco, Ayla O Manughian-Peter, Matthew P Salomon, and Diego M Marzese

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A phase Ib study of pre-operative, locoregional IRX-2 cytokine immunotherapy to prime immune responses in patients with early stage breast cancer., David B Page, Joanna Pucilowska, Katherine G Sanchez, Alison K Conlin, Anupama Acheson, Kelly S Perlewitz, James H Imatani, Shagheyegh Aliabadi-Wahle, Nikki Moxon, Staci Mellinger, Amanda Y Seino, Maritza Martel, Yaping Wu, Zhaoyu Sun, William L. Redmond, Valerie Conrad, Venkatesh Rajamanickam, Dottie Waddell, Deborah Laxague, Monil Shah, Shu-Ching Chang, and Walter Urba

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Real-world treatment patterns and adverse events in metastatic renal cell carcinoma from a large US claims database., Sumanta Pal, Jun Gong, Shivani K Mhatre, Shih-Wen Lin, Andy Surinach, Sarika Ogale, Rini Vohra, Herschel Wallen, and Daniel George

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Preoperative stimulation of resolution and inflammation blockade eradicates micrometastases., Dipak Panigrahy, Allison Gartung, Jun Yang, Haixia Yang, Molly M Gilligan, Megan L Sulciner, Swati S Bhasin, Diane R Bielenberg, Jaimie Chang, Birgitta A Schmidt, Julia Piwowarski, Anna Fishbein, Dulce Soler-Ferran, Matthew A Sparks, Steven J Staffa, Vidula Sukhatme, Bruce D Hammock, Mark W Kieran, Sui Huang, Manoj Bhasin, Charles N Serhan, and Vikas P Sukhatme

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First-In-Human Study of Cemiplimab Alone or In Combination with Radiotherapy and/or Low Dose Cyclophosphamide in Patients with Advanced Malignancies., Kyriakos P Papadopoulos, Melissa L Johnson, Albert Craig Lockhart, Kathleen N Moore, Gerald S Falchook, Silvia C Formenti, Aung Naing, Richard D Carvajal, Lee S Rosen, Glen J Weiss, Rom Leidner, Jingjin Li, Anne Paccaly, Minjie Feng, Elizabeth Stankevich, Israel Lowy, Matthew G Fury, and Marka R Crittenden

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Unique Neoantigens Arise from Somatic Mutations in Patients with Gastrointestinal Cancers., Maria R Parkhurst, Paul F Robbins, Eric Tran, Todd D Prickett, Jared J Gartner, Li Jia, Gabriel Ivey, Yong F Li, Mona El-Gamil, Almin Lalani, Jessica S Crystal, Abraham Sachs, Eric Groh, Satyajit Ray, Lien T Ngo, Scott Kivitz, Anna Pasetto, Rami Yossef, Frank J Lowery, Stephanie L Goff, Winifred Lo, Gal Cafri, Drew C Deniger, Parisa Malekzadeh, Mojgan Ahmadzadeh, John R Wunderlich, Robert P T Somerville, and Steven A Rosenberg

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Peritumoral administration of DRibbles-pulsed antigen-presenting cells enhances the antitumor efficacy of anti-GITR and anti-PD-1 antibodies via an antigen presenting independent mechanism., Jaina M Patel, Zhihua Cui, Zhi-Fa Wen, Catherine T Dinh, and Hong-Ming Hu

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Duvelisib for CLL/SLL and Follicular Non-Hodgkin Lymphoma., Krish Patel, Alexey Danilov, and John M Pagel

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Duvelisib for CLL/SLL and follicular non-Hodgkin lymphoma., Krish Patel, Alexey V Danilov, and John M Pagel

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Exploring a Future for PI3K Inhibitors in Chronic Lymphocytic Leukemia., Krish Patel and John M Pagel

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Impact of dosing frequency (once daily or twice daily) on patient adherence to oral targeted therapies for hematologic malignancies: a retrospective cohort study among managed care enrollees., Krish Patel, Vinjamuri S Sudhir, Shaum Kabadi, Joanna C Huang, Sanchita Porwal, Kushan Thakkar, and John M Pagel

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Analysis of cell-free circulating tumor DNA in 419 patients with glioblastoma and other primary brain tumors., David E Piccioni, Achal Singh Achrol, Lesli A Kiedrowski, Kimberly C Banks, Najee Boucher, Garni Barkhoudarian, Daniel F Kelly, Tiffany Juarez, Richard B Lanman, Victoria M Raymond, Minhdan Nguyen, Judy D Truong, Annie Heng, Jaya Mini Gill, Marlon G Saria, Sandeep C Pingle, and Santosh Kesari

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Comprehensive Genomic Tumor Profiling, Brian D. Piening

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Glioblastoma Mimicking Viral Encephalitis Responds to Acyclovir: A Case Series and Literature Review., Keenan J Piper, Haidn Foster, Brandon Gabel, Burt Nabors, and Charles Cobbs

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Blockade of TGF-β signaling to enhance the antitumor response is accompanied by dysregulation of the functional activity of CD4, Magdalena J Polanczyk, Edwin Walker, Daniel Haley, Bella S Guerrouahen, and Emmanuel T Akporiaye

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A Pan-Cancer Approach to Predict Responsiveness to Immune Checkpoint Inhibitors by Machine Learning., Maurizio Polano, Marco Chierici, Michele Dal Bo, Davide Gentilini, Federica Di Cintio, Lorena Baboci, David L Gibbs, Cesare Furlanello, and Giuseppe Toffoli

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OX40 Agonist Tumor Immunotherapy Does Not Impact Regulatory T Cell Suppressive Function., Fanny Polesso, Minhaz Sarker, Andrew D Weinberg, Susan E Murray, and Amy E Moran

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OX40 Agonist Tumor Immunotherapy Does Not Impact Regulatory T Cell Suppressive Function., Fanny Polesso, Minhaz Sarker, Andrew D Weinberg, Susan E Murray, and Amy E Moran

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Recurrence After Robotic Retroperitoneal Lymph Node Dissection Raises More Questions than Answers., James R Porter, Scott Eggener, Erik Castle, and Phillip Pierorazio

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Regeneration Enhances Metastasis: A Novel Role for Neurovascular Signaling in Promoting Melanoma Brain Metastasis., Roshini Prakash, Sivan Izraely, Nikita S Thareja, Rex H Lee, Maya Rappaport, Riki Kawaguchi, Orit Sagi-Assif, Shlomit Ben-Menachem, Tsipi Meshel, Michal Machnicki, Shuichi Ohe, Dave S B Hoon, Giovanni Coppola, Isaac P Witz, and S Thomas Carmichael

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Immunological Complexity of the Prostate Cancer Microenvironment Influences the Response to Immunotherapy., Nataliya Prokhnevska, Dana A Emerson, Haydn T Kissick, and William L. Redmond

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Upregulation of Ganglioside GD3 Synthase (ST8SIA1) Promotes Distant Organ Metastasis In Melanoma Patients, Irene Ramos

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Renal Considerations in the Oncology Patient, Sridhar K. Reddy

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Non-TB Mycobacterial Infection-Bronchiectasis Nexus., Jerome M Reich

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Non-TB Mycobacterial Infection-Bronchiectasis Nexus., Jerome M Reich

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Two Radiographic Features Favoring Radiation Pneumonitis in the Differential Diagnosis., Jerome M Reich

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Current Controversies in Cardiothoracic Imaging: Low-dose Computerized Tomographic Overdiagnosis of Lung Cancer is Substantial; Its Consequences are Underappreciated-Point., Jerome M Reich and Jong S Kim

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Earlier Diagnosis Not Self-Evidently Beneficial: Natural History of Subcentimeter Lung Cancers., Jerome M Reich and Jong S Kim

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Birds of a Feather? Genetic Counseling, Genetic Testing, and Humanism., Robert Resta

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INTRODUCTION TO EXPLORING THE EXOME SPECIAL ISSUE., Robert Resta, Jennifer Sullivan, and Allyn McConkie-Rosell

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Provider Attitudes and Practice Patterns for Direct-Acting Antiviral Therapy for Patients with Hepatocellular Carcinoma., Nicole E Rich, Ju Dong Yang, Ponni V Perumalswami, Naim Alkhouri, Whitney Jackson, Neehar D Parikh, Neil Mehta, Reena Salgia, Andres Duarte-Rojo, Laura Kulik, Mina Rakoski, Adnan Said, Omobonike Oloruntoba, George N Ioannou, Maarouf A Hoteit, Andrew M Moon, Amol S Rangnekar, Sheila L Eswaran, Elizabeth Zheng, Janice H Jou, James Hanje, Anjana Pillai, Ruben Hernaez, Robert Wong, Steven Scaglione, Hrishikesh Samant, Devika Kapuria, Shaun Chandna, Russell Rosenblatt, Veeral Ajmera, Catherine Frenette, Sanjaya K Satapathy, Parvez Mantry, Prasun Jalal, Binu V John, Oren K Fix, Michael Leise, Christina C Lindenmeyer, Avegail Flores, Nayan Patel, Z Gordon Jiang, Nyan Latt, Renumathy Dhanasekaran, Mobolaji Odewole, Sofia Kagan, Jorge A Marrero, and Amit G Singal

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Phase Ib with expansion study of olaparib plus weekly (Metronomic) carboplatin and paclitaxel in relapsed ovarian cancer patients., Saul Eugene Rivkin, James Moon, Desiree S Iriarte, Erik Bailey, Heather L Sloan, Gary E Goodman, Amy E BonDurant, Dan Velijovich, Tanya Wahl, Peter Jiang, Chirag A Shah, Charles Drescher, MF Fer, Henry G Kaplan, and Erin D Ellis

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Tumor Lysis, Adverse Events, and Dose Adjustments in 297 Venetoclax-Treated CLL Patient in Routine Clinical Practice., Lindsey E Roeker, Christopher P Fox, Toby A Eyre, Danielle M Brander, John N Allan, Stephen J Schuster, Chadi Nabhan, Brian T Hill, Nirav N Shah, Frederick Lansigan, Maryam Yazdy, Bruce D Cheson, Nicole Lamanna, Arun K Singavi, Catherine C Coombs, Paul M Barr, Alan P Skarbnik, Mazyar Shadman, Chaitra S Ujjani, Hande H Tuncer, Allison M Winter, Joanna Rhodes, Colleen Dorsey, Hannah Morse, Charlene Kabel, John M Pagel, Annalynn M Williams, Ryan Jacobs, Andre Goy, Sivraj Muralikrishnan, Laurie Pearson, Andrea Sitlinger, Neil Bailey, Anna Schuh, Amy A Kirkwood, and Anthony R Mato

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Nomogram for Predicting Individual Survival After Recurrence of Advanced-Stage, High-Grade Ovarian Carcinoma., Peter G Rose, James J Java, Ritu Salani, Melissa A Geller, Angeles Alvarez Secord, Krishnansu S Tewari, David P Bender, David G Mutch, Michael L Friedlander, Linda Van Le, Michael W Method, Chad A Hamilton, Roger B Lee, Robert M Wenham, Saketh R Guntupalli, Maurie Markman, Franco M Muggia, Deborah K Armstrong, Michael A Bookman, Robert A Burger, and Larry J Copeland

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Cervical cancer in Tanzania: A systematic review of current challenges in six domains., Ava S Runge, Megan E Bernstein, Alexa N Lucas, and Krishnansu S Tewari

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Immunotherapy Toxicities., Katherine Sanchez, David B Page, and Walter Urba

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Phase I/II trial of nano-camptothecin CRLX101 with capecitabine and radiotherapy as neoadjuvant treatment for locally advanced rectal cancer., Hanna K Sanoff, Dominic H Moon, Dominic T Moore, Jeremiah Boles, Courtney Bui, William Blackstock, Bert H O'Neil, Somasundaram Subramaniam, Autumn J McRee, Cheryl Carlson, Michael S Lee, Joel E Tepper, and Andrew Z Wang

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ASO Author Reflections: The Changing Landscape for Industry Support to Surgical Oncologists., Juan A Santamaria-Barria and Anton J Bilchik

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Changing Trends in Industry Funding for Surgical Oncologists., Juan A Santamaria-Barria, Stacey L Stern, Adam Khader, Mary Garland-Kledzik, Anthony J Scholer, Trevan D Fischer, and Anton J Bilchik

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Hospitalized patients quantify verbal pain intensity descriptors: methodological issues and values for 26 descriptors., Judith M Schlaeger, Kevin C Cain, Erin K Myklebust, Keesha L Powell-Roach, Brenda W Dyal, and Diana J Wilkie

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Developing "Nurse AMIE": A tablet-based supportive care intervention for women with metastatic breast cancer., Kathryn H Schmitz, Xiaochen Zhang, Renate Winkels, Erica Schleicher, Katlynn Mathis, Shawna Doerksen, Leah Cream, Jennifer Rosenberg, Rena Kass, Michelle Farnan, Patricia Halpin-Murphy, Robin Suess, David S Zucker, and Michael Hayes

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Downregulation of CENPF Remodels Prostate Cancer Cells and Alters Cellular Metabolism., Muhammad Shahid, Minhyung Kim, Min Young Lee, Austin Yeon, Sungyong You, Hyung L Kim, and Jayoung Kim

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Downregulation of CENPF Remodels Prostate Cancer Cells and Alters Cellular Metabolism., Muhammad Shahid, Minhyung Kim, Min Young Lee, Austin Yeon, Sungyong You, Hyung L Kim, and Jayoung Kim

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Glioblastoma: Biology, Diagnosis, and Treatment, Akanksha Sharma, Maciej M. Mrugala, and Jan Buckner

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ELEVATE TN: Phase 3 Study of Acalabrutinib Combined with Obinutuzumab (O) or Alone Vs O Plus Chlorambucil (Clb) in Patients (Pts) with Treatment-Naive Chronic Lymphocytic Leukemia (CLL)., Jeff P Sharman, Versha Banerji, Laura Maria Fogliatto, Yair Herishanu, Talha Munir, Renata Walewska, George Follows, Karin Karlsson, Paolo Ghia, Gillian Corbett, Patricia Walker, Miklos Egyed, Wojciech Jurczak, Gilles Salles, Ann Janssens, Florence Cymbalista, William G Wierda, Steven Coutre, John M Pagel, Alan Skarbnik, Manali Kamdar, Jennifer Woyach, Raquel Izumi, Veerendra Munugalavadla, Priti Patel, Min Hui Wang, Sofia Wong, and John C Byrd

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Final Results of a Randomized, Phase III Study of Rituximab With or Without Idelalisib Followed by Open-Label Idelalisib in Patients With Relapsed Chronic Lymphocytic Leukemia., Jeff P Sharman, Steven E Coutre, Richard R Furman, Bruce D Cheson, John M Pagel, Peter Hillmen, Jacqueline C Barrientos, Andrew D Zelenetz, Thomas J Kipps, Ian W Flinn, Paolo Ghia, Herbert Eradat, Thomas Ervin, Nicole Lamanna, Bertrand Coiffier, Andrew R Pettitt, Shuo Ma, Eugen Tausch, Paula Cramer, Julie Huang, Siddhartha Mitra, Michael Hallek, Susan M O'Brien, and Stephan Stilgenbauer

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Melanoma Within Basal Cell Carcinoma Nests Discovered During Mohs Micrographic Surgery., Christine M Shaver, Steven E Kolker, and Richard G Bennett

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Body Mass Index (BMI), BMI Change, and Overall Survival in Patients With SCLC and NSCLC: A Pooled Analysis of the International Lung Cancer Consortium., Daniel Shepshelovich, Wei Xu, Lin Lu, Aline Fares, Ping Yang, David Christiani, Jie Zhang, Kouya Shiraishi, Brid M Ryan, Chu Chen, Ann G Schwartz, Adonina Tardon, Xifeng Wu, Matthew B Schabath, M Dawn Teare, Loic Le Marchand, Zuo-Feng Zhang, John K Field, Hermann Brenner, Nancy Diao, Juntao Xie, Takashi Kohno, Curtis C Harris, Angela S Wenzlaff, Guillermo Fernandez-Tardon, Yuanqing Ye, Fiona Taylor, Lynne R Wilkens, Michael Davies, Yi Liu, Matt J Barnett, Gary E Goodman, Hal Morgenstern, Bernd Holleczek, M Catherine Brown, Geoffrey Liu, and Rayjean Hung

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Trifluridine/tipiracil (FTD/TPI) in patients (pts) aged ≥65 years with metastatic gastric/gastroesophageal junction cancer (mGC/mGEJC): Subgroup analysis from TAGS., Kohei Shitara, Toshihiko Doi, Hisashi Hosaka, Peter C. Thuss-Patience, Armando Santoro, Paula Jiménez-Fonseca, Federico Longo, Ozgur Ozyilkan, Irfan Cicin, David Park, Mohamedtaki Abdulaziz Tejani, Aziz Zaanan, Domenico Bilancia, Carles Pericay, Mustafa Ozguroglu, Maria Alsina, Lukas Makris, Sandra McGuigan, and David H. Ilson

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High-Dose Ipilimumab and High-Dose Interleukin-2 for Patients With Advanced Melanoma., Ann W Silk, Howard L Kaufman, Brendan Curti, Janice M Mehnert, Kim Margolin, David McDermott, Joseph Clark, Jenna Newman, Praveen K Bommareddy, Lisa Denzin, Saltanat Najmi, Azra Haider, Weichung Shih, Michael P Kane, and Andrew Zloza

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Oncoplastic Breast Surgery: From Oblivion to Mainstream., Melvin J Silverstein

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The Breast Centers That Almost Never Were., Melvin J Silverstein

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Immunotherapy for Head and Neck Cancer., Felix Sim, Rom Leidner, and Richard Bryan Bell

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Immunotherapy for Head and Neck Cancer., Felix Sim, Rom Leidner, and Richard Bryan Bell

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Immunotherapy for Head and Neck Cancer., Felix Sim, Rom Leidner, and Richard Bryan Bell

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Primary Cardiac Sarcoma: A Rare, Aggressive Malignancy with a High Propensity for Brain Metastases., Brittany L Siontis, Lili Zhao, Monika Leja, Jonathan B McHugh, Maryann M Shango, Laurence H Baker, Scott M Schuetze, and Rashmi Chugh

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Painting a portrait: Analysis of national health survey data for cancer genetic counseling., Monica H Stamp, Ora K Gordon, Christopher P Childers, and Kimberly K Childers

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Major pathologic response on biopsy (MPRbx) in patients with advanced melanoma treated with anti-PD-1: evidence for an early, on-therapy biomarker of response., J E Stein, A Soni, L Danilova, T R Cottrell, T F Gajewski, F S Hodi, S Bhatia, W J Urba, W H Sharfman, M Wind-Rotolo, R Edwards, E J Lipson, and J M Taube

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A multi-institutional analysis of 263 hilar tumors during robot-assisted partial nephrectomy., Peter L Sunaryo, David J Paulucci, Kennedy Okhawere, Alp Tuna Beksac, John P Sfakianos, Ronney Abaza, Daniel D Eun, Akshay Bhandari, Ashok K Hemal, James R Porter, and Ketan K Badani

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Subcellular compartmentalization of PKM2 identifies anti-PKM2 therapy response in vitro and in vivo mouse model of human non-small-cell lung cancer., Akiko Suzuki, Sachin Puri, Pamela Leland, Ankit Puri, Tarsem Moudgil, Bernard A Fox, Raj K Puri, and Bharat H Joshi

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Colon cancer as a subsequent malignant neoplasm in young adults., Annabelle Teng, Daniel Nelson, Ahmed N Dehal, Shu-Ching Chang, Trevan D Fischer, Scott R Steele, and Melanie Goldfarb

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Implications of Prolonged Time to Pancreaticoduodenectomy After Neoadjuvant Chemoradiation., Annabelle Teng, Trang Nguyen, Anton J Bilchik, Victoria O'Connor, and David Y Lee

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Pediatric gastric adenocarcinoma: A National Cancer Data Base review., Robert A Tessler, Matthew Dellinger, Morgan K Richards, Adam B Goldin, Elizabeth A Beierle, John J Doski, Melanie Goldfarb, Monica Langer, Jed G Nuchtern, Mehul V Raval, Sanjeev Vasudevan, and Kenneth W Gow

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Recurrence of Melanoma After a Negative Sentinel Node Biopsy: Predictors and Impact of Recurrence Site on Survival., Daniel C Thomas, Gang Han, Stanley P Leong, Mohammed Kashani-Sabet, John Vetto, Barbara Pockaj, Richard L White, Mark B Faries, Schlomo Schneebaum, Nicola Mozzillo, Kim J Charney, Vernon K Sondak, Jane L Messina, Jonathan S Zager, and Dale Han

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Recurrence of Melanoma After a Negative Sentinel Node Biopsy: Predictors and Impact of Recurrence Site on Survival., Daniel C Thomas, Gang Han, Stanley P Leong, Mohammed Kashani-Sabet, John Vetto, Barbara Pockaj, Richard L White, Mark B Faries, Schlomo Schneebaum, Nicola Mozzillo, Kim J Charney, Vernon K Sondak, Jane L Messina, Jonathan S Zager, and Dale Han

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Preoperative Ultrasound Assessment of Regional Lymph Nodes in Melanoma Patients Does not Provide Reliable Nodal Staging: Results from a Large Multicenter Trial., John F Thompson, Lauren E Haydu, Roger F Uren, Robert H Andtbacka, Jonathan S Zager, Peter D Beitsch, Doreen M Agnese, Nicola Mozzillo, Alessandro Testori, Tawnya L Bowles, Harald J Hoekstra, Mark C Kelley, Jeffrey Sussman, Schlomo Schneebaum, B Mark Smithers, Gregory McKinnon, Eddy Hsueh, Lisa Jacobs, Erwin Schultz, Douglas Reintgen, John M Kane, Erica B Friedman, Hejing Wang, Lisa Van Kreuningen, Vicki Schiller, David A Elashoff, Robert Elashoff, Alistair J Cochran, Stacey Stern, and Mark B Faries

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Predictive Markers Require Thorough Analytic Validation., Megan L Troxell, Regan S Fulton, Paul E Swanson, Andrew M Bellizzi, Patrick L Fitzgibbons, Abiy B Ambaye, Thomas S Haas, Jeffrey D Goldsmith, Patti A Loykasek, Dylan V Miller, Dennis O'Malley, Jingxin Qiu, Mohamed E Salama, Kurt B Schaberg, Robert A Schwartz, Jinru Shia, Thomas A Summers, and Yaping Wu

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Mild Cognitive Deficits from Cancer Treatments, Jason Tse

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Development and Pilot Testing of an Assessment Tool for Performance of Invasive Mediastinal Staging., Simon R Turner, Basil S Nasir, Hollis Lai, Kazuhiro Yasufuku, Colin Schieman, Brian E Louie, and Eric Lr Bédard

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The Immune Microenvironment Impacts Survival in Western Patients with Gastric Adenocarcinoma., Abhineet Uppal, Ahmed N Dehal, Shu-Ching Chang, Dany Barrak, Yalda Naeini, John R Jalas, and Anton J Bilchik

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Regional Node Basin Recurrence in Melanoma Patients: More Common After Node Dissection for Macroscopic Rather than Clinically Occult Nodal Disease., Abhineet Uppal, Stacey L Stern, John F Thompson, Leland J Foshag, Nicola Mizzollo, Omgo E Nieweg, Harald J Hoekstra, Daniel F Roses, Vernon K Sondak, Mohammed Kashani-Sabet, Brendon J Coventry, Alistair J Cochran, Manabu Fujita, Myung Sim-Shin, David Elashoff, Robert M Elashoff, and Mark B Faries

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Duodenal GI stromal tumors: Is radical resection necessary?, Abhineet Uppal, Mansen Wang, Trevan D Fischer, and Melanie Goldfarb

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Yttrium-90-labeled anti-CD45 antibody followed by a reduced-intensity hematopoietic cell transplantation for patients with relapsed/refractory leukemia or myelodysplasia., Phuong Vo, Ted A Gooley, Joseph G Rajendran, Darrell R Fisher, Johnnie J Orozco, Damian J Green, Ajay K Gopal, Robyn Haaf, Margaret Nartea, Rainer Storb, Frederick R Appelbaum, Oliver W Press, John M Pagel, and Brenda M Sandmaier

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A Simple Measure of Hepatocellular Carcinoma Burden Predicts Tumor Recurrence after Liver Transplantation: The RH-IML Classification., Philip Vutien, Jennifer Dodge, Kiran M Bambha, Eric M Nordstrom, Jane Gralla, Kristen Campbell, Claire Levek, Trevor Nydam, Oren Fix, George Ioannou, and Scott W Biggins

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A Simple Measure of Hepatocellular Carcinoma Burden Predicts Tumor Recurrence After Liver Transplantation: The Recurrent Hepatocellular Carcinoma-Initial, Maximum, Last Classification., Philip Vutien, Jennifer Dodge, Kiran M Bambha, Eric M Nordstrom, Jane Gralla, Kristen Campbell, Claire Levek, Trevor Nydam, Oren K Fix, George Ioannou, and Scott W Biggins

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The Cancer Immunotherapy Biomarker Testing Landscape., Eric E Walk, Sophia L Yohe, Amy Beckman, Andrew Schade, Mary M Zutter, John Pfeifer, and Anna B Berry

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Phase 1 Trial of Fruquintinib in Patients with Advanced Solid Tumors: Results of the Dose Escalation Phase., A Wang-Gillam, H Park, H Yeckes-Rodin, Thomas Stanton, M Kosmo, S Fan, N Sauter, and M Kanie

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Programmed Cell Death Receptor (PD-1) Ligand (PD-L1) expression in Philadelphia chromosome-negative myeloproliferative neoplasms., Jen-Chin Wang, Chi Chen, Ajay Kundra, Sreenath Kodali, Anita Pandey, Ching Wong, Tony Cheung, Vladimir Gotlieb, Gardith Joseph, and Sophia Tribie

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Pancreatic islet cell tumors in adolescents and young adults., Alicia M Waters, Ilan I Maizlin, Robert T Russell, Matthew Dellinger, Kenneth W Gow, Adam Goldin, Melanie Goldfarb, Jed G Nuchtern, Monica Langer, Sanjeev A Vasudevan, John J Doski, Mehul Raval, and Elizabeth A Beierle

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Prevalence of trismus in patients with head and neck cancer: A systematic review with meta-analysis., Amber L Watters, Shane Cope, Meir N Keller, Mariela Padilla, and Reyes Enciso

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Special Issue on Single-Cell Multiomics for Immuno-Oncology and Cancer Systems Biology., Wei Wei and Rong Fan

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A Randomized Double-Blind Placebo-Controlled Phase 2 Trial Of Dendritic Cell Vaccine ICT-107 In Newly Diagnosed Patients With Glioblastoma., Patrick Y Wen, David A Reardon, Terri S Armstrong, Surasak Phuphanich, Robert D Aiken, Joseph C Landolfi, William T Curry, Jay-Jiguang Zhu, Michael Glantz, David M Peereboom, James Markert, Renato LaRocca, Donald M O'Rourke, Karen Fink, Lyndon Kim, Michael Gruber, Glenn J Lesser, Edward Pan, Santosh Kesari, Alona Muzikansky, Clemencia Pinilla, Radleigh G Santos, and John S Yu

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Buparlisib in Patients With Recurrent Glioblastoma Harboring Phosphatidylinositol 3-Kinase Pathway Activation: An Open-Label, Multicenter, Multi-Arm, Phase II Trial., Patrick Y Wen, Mehdi Touat, Brian M Alexander, Ingo K Mellinghoff, Shakti Ramkissoon, Christine S McCluskey, Kristine Pelton, Sam Haidar, Sankha S Basu, Sarah C Gaffey, Loreal E Brown, Juan Emmanuel Martinez-Ledesma, Shaofang Wu, Jungwoo Kim, Wei Wei, Mi-Ae Park, Jason T Huse, John G Kuhn, Mikael L Rinne, Howard Colman, Nathalie Y R Agar, Antonio M Omuro, Lisa M DeAngelis, Mark R Gilbert, John F de Groot, Timothy F Cloughesy, Andrew S Chi, Thomas M Roberts, Jean J Zhao, Eudocia Q Lee, Lakshmi Nayak, James R Heath, Laura L Horky, Tracy T Batchelor, Rameen Beroukhim, Susan M Chang, Azra H Ligon, Ian F Dunn, Dimpy Koul, Geoffrey S Young, Michael D Prados, David A Reardon, W K Alfred Yung, and Keith L Ligon

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Buparlisib in Patients With Recurrent Glioblastoma Harboring Phosphatidylinositol 3-Kinase Pathway Activation: An Open-Label, Multicenter, Multi-Arm, Phase II Trial., Patrick Y Wen, Mehdi Touat, Brian M Alexander, Ingo K Mellinghoff, Shakti Ramkissoon, Christine S McCluskey, Kristine Pelton, Sam Haidar, Sankha S Basu, Sarah C Gaffey, Loreal E Brown, Juan Emmanuel Martinez-Ledesma, Shaofang Wu, Jungwoo Kim, Wei Wei, Mi-Ae Park, Jason T Huse, John G Kuhn, Mikael L Rinne, Howard Colman, Nathalie Y R Agar, Antonio M Omuro, Lisa M DeAngelis, Mark R Gilbert, John F de Groot, Timothy F Cloughesy, Andrew S Chi, Thomas M Roberts, Jean J Zhao, Eudocia Q Lee, Lakshmi Nayak, James R Heath, Laura L Horky, Tracy T Batchelor, Rameen Beroukhim, Susan M Chang, Azra H Ligon, Ian F Dunn, Dimpy Koul, Geoffrey S Young, Michael D Prados, David A Reardon, W K Alfred Yung, and Keith L Ligon

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Atezolizumab in combination with carboplatin plus nab-paclitaxel chemotherapy compared with chemotherapy alone as first-line treatment for metastatic non-squamous non-small-cell lung cancer (IMpower130): a multicentre, randomised, open-label, phase 3 trial., Howard J. West, Michael McCleod, Maen Hussein, Alessandro Morabito, Achim Rittmeyer, Henry J Conter, Hans-Georg Kopp, Davey Daniel, Steven McCune, Tarek Mekhail, Alona Zer, Niels Reinmuth, Ahad Sadiq, Alan Sandler, Wei Lin, Tania Ochi Lohmann, Venice Archer, Lijia Wang, Marcin Kowanetz, and Federico Cappuzzo

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Navigation’s Impact on Clinical Trial Participation in Cancer Research: Barriers, Evidence, and Strategies, Claire White, Laura Hynes, Lucy J. Gansauer, Mary Van Cleave, Lavinia Dobrea, Amy Meleason, and Daniel McGough

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Recurrence rates for patients with early-stage breast cancer treated with IOERT at a community hospital per the ASTRO consensus statement for APBI., Venita L Williams, Tanuja Bhandari, Lillian J Chen, Lawrence D Wagman, Michele Carpenter, Jay K Harness, Rajesh Khanijou, Maher Gobran, Windy Olaya, Melissa I Carandang, and Robert B Ash

Lung cancer screening: Implementation in a multi-state, community-based setting The International Association for the Study of Lung Cancer 20th World Conference on Lung Cancer Barcelona, Candice L. Wilshire

Relationship between lung cancer screening centers in the United States and high-risk individuals The International Association for the Study of Lung Cancer 20th World Conference on Lung Cancer Barcelona, Spain, Candice L. Wilshire

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Expression and effects of leukemia inhibitory factor on nucleus pulposus degeneration., Qiang Xiao, Ji-Huan Zeng, Hao Zhou, Quan-He Qiu, Bo Ke, Liang Deng, Zhen-Ming Hu, Jeffrey Roh, and Min Dai

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Small Molecule KRAS Agonist for Mutant KRAS Cancer Therapy., Ke Xu, Dongkyoo Park, Andrew T Magis, Jun Zhang, Wei Zhou, Gabriel L Sica, Suresh S Ramalingam, Walter J Curran, and Xingming Deng

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Repurposed Drugs in Treating Glioblastoma Multiforme: Clinical Trials Update., S Yadavalli, V M Yenugonda, and S Kesari

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Activation of Wnt signaling promotes olaparib resistant ovarian cancer., Tomomi M Yamamoto, Alexandra McMellen, Zachary L Watson, Jennifer Aguilera, Rebecca Ferguson, Elmar Nurmemmedov, Tanay Thakar, George-Lucian Moldovan, Hyunmin Kim, Diana M Cittelly, Annette M Joglar, Elyse P Brennecke, Heidi Wilson, Kian Behbakht, Matthew J Sikora, and Benjamin G Bitler

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Toxicities and Outcomes of Acalabrutinib-Treated Patients with Chronic Lymphocytic Leukemia: A Retrospective Analysis of Real World Patients, Maryam Sarraf Yazdy, John M Pagel, Neil Bailey, Krish Patel, and See full list of authors in comments

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How Many Nodes Need to be Removed to Make Esophagectomy an Adequate Cancer Operation, and Does the Number Change When a Patient has Chemoradiotherapy Before Surgery?, Jonathan C Yeung, Manjit S Bains, Arianna Barbetta, Tamar Nobel, Steven R DeMeester, Brian E Louie, Mark B Orringer, Linda W Martin, Rishindra M Reddy, Francisco Schlottmann, and Daniela Molena

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Daratumumab, bortezomib, cyclophosphamide and dexamethasone in newly diagnosed and relapsed multiple myeloma: LYRA study., Habte Yimer, Jason Melear, Edward Faber, William Bensinger, John M Burke, Mohit Narang, Don Stevens, Sriya Gunawardena, Yana Lutska, Keqin Qi, Jon Ukropec, Ming Qi, Thomas S Lin, and Robert M Rifkin

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Daratumumab, bortezomib, cyclophosphamide and dexamethasone in newly diagnosed and relapsed multiple myeloma: LYRA study., Habte Yimer, Jason Melear, Edward Faber, William Bensinger, John M Burke, Mohit Narang, Don Stevens, Sriya Gunawardena, Yana Lutska, Keqin Qi, Jon Ukropec, Ming Qi, Thomas S Lin, and Robert M Rifkin

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A systems approach to clinical oncology uses deep phenotyping to deliver personalized care., James T Yurkovich, Qiang Tian, Nathan D Price, and Leroy Hood

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A microbial-based cancer vaccine for induction of EGFRvIII-specific CD8+ T cells and anti-tumor immunity., Lauren Zebertavage, Shelly Bambina, Jessica Shugart, Alejandro Alice, Kyra D Zens, Peter Lauer, Bill Hanson, Michael J. Gough, Marka R Crittenden, and Keith S Bahjat

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STAT3 Activation-Induced Fatty Acid Oxidation in CD8, Chunyan Zhang, Chanyu Yue, Andreas Herrmann, Jieun Song, Colt Egelston, Tianyi Wang, Zhifang Zhang, Wenzhao Li, Heehyoung Lee, Maryam Aftabizadeh, Yi Jia Li, Peter P Lee, Stephen Forman, George Somlo, Peiguo Chu, Laura Kruper, Joanne Mortimer, Dave S B Hoon, Wendong Huang, Saul Priceman, and Hua Yu