The Cancer Institute is a leader in cutting-edge treatments. Using a truly multidisciplinary approach, patients have access to advanced diagnostics, minimally invasive surgical interventions, and personalized genomic and immune-oncologic treatment options. Our team of cancer specialists – many of whom completed fellowships and specialty training at prestigious academic centers – offers comprehensive services for individuals with a cancer diagnosis.

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Submissions from 2018

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Improvement in TNM staging of pulmonary neuroendocrine tumors requires histology and regrouping of tumor size., Maria Cattoni, Eric Vallières, Lisa M Brown, Amir A Sarkeshik, Stefano Margaritora, Alessandra Siciliani, Pier Luigi Filosso, Francesco Guerrera, Andrea Imperatori, Nicola Rotolo, Farhood Farjah, Grace Wandell, Kimberly E Costas, Catherine Mann, Michal Hubka, Stephen Kaplan, Alexander S Farivar, Ralph W Aye, and Brian E Louie

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Early Identification of Intracranial Hemorrhage Using a Predictive Nomogram, Frances Chandler, Joyce Kane, Amanda Blackford, Margaux Weinberger, Kavitha Wagner, Ivana Gojo, Melanie Cohen, and Colleen Apostol

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Chemotherapy-generated cell debris stimulates colon carcinoma tumor growth via osteopontin., Jaimie Chang, Swati S Bhasin, Diane R Bielenberg, Vikas P Sukhatme, Manoj Bhasin, Sui Huang, Mark W Kieran, and Dipak Panigrahy

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Evaluating the potential benefit of reduced planning target volume margins for low and intermediate risk patients with prostate cancer using real-time electromagnetic tracking., Avinash R Chaurasia, Kelly J Sun, Christopher Premo, Timothy Brand, Brent Tinnel, Stacie Barczak, John Halligan, Michael Brown, and Dusten Macdonald

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Programmed Cell Death Receptor (PD-1), PD-1 Ligand (PD-L1) Expression in Philadelphia Chromosome Negative Myeloid Neoplasms, Chi Chen, Anita Pandey, Ajay Kundra, Sreenath Kodali, Ching Wong, Tony W. Cheung, Vladimir K. Gotlieb, Gardith Joseph, Sophia Tribie, and Jen-Chin Wang

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A Phase II Study of Celecoxib With Irinotecan, 5-Fluorouracil, and Leucovorin in Patients With Previously Untreated Advanced or Metastatic Colorectal Cancer., Emerson Y Chen, Charles D Blanke, Daniel G Haller, Al B Benson, Tomislav Dragovich, Heinz-Josef Lenz, Carlos Robles, Hong Li, Motomi Mori, Nora Mattek, Rachel E Sanborn, and Charles D Lopez

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Targeting Mcl-1 enhances DNA replication stress sensitivity to cancer therapy., Guo Chen, Andrew T Magis, Ke Xu, Dongkyoo Park, David S Yu, Taofeek K Owonikoko, Gabriel L Sica, Sarah W Satola, Suresh S Ramalingam, Walter J Curran, Paul W Doetsch, and Xingming Deng

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Blocking immunoinhibitory receptor LILRB2 reprograms tumor-associated myeloid cells and promotes antitumor immunity., Hui-Ming Chen, William van der Touw, Yuan Shuo Wang, Kyeongah Kang, Sunny Mai, Jilu Zhang, Dayanira Alsina-Beauchamp, James A Duty, Sathish Kumar Mungamuri, Bin Zhang, Thomas Moran, Richard Flavell, Stuart Aaronson, Hong-Ming Hu, Hisashi Arase, Suresh Ramanathan, Raja Flores, Ping-Ying Pan, and Shu-Hsia Chen

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Histopathology of locally advanced colorectal carcinoma, with emphasis on tumor invasion of adherent peritoneal membranes., Jey-Hsin Chen

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Relapse pathway of glioblastoma revealed by single-cell molecular analysis., Xuelian Chen, Qin Wen, Andres Stucky, Yunjing Zeng, Shengjia Gao, William G Loudon, Hector W Ho, Mustafa H Kabeer, Shengwen Calvin Li, Xi Zhang, and Jiang F Zhong

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Phase IIIb safety results from an expanded-access protocol of talimogene laherparepvec for patients with unresected, stage IIIB-IVM1c melanoma., Jason Chesney, Sanjay Awasthi, Brendan Curti, Laura Hutchins, Gerald Linette, Pierre Triozzi, Marcus C B Tan, Russell E Brown, John Nemunaitis, Eric Whitman, Christopher Windham, Jose Lutzky, Gerald F Downey, Nicolas Batty, and Thomas Amatruda

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Reply to S. Nakamura et al and S. Narod et al., Christopher P Childers, Kimberly K Childers, Melinda Maggard-Gibbons, and James Macinko

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National Distribution of Cancer Genetic Testing in the United States: Evidence for a Gender Disparity in Hereditary Breast and Ovarian Cancer., Kimberly K Childers, Melinda Maggard-Gibbons, James Macinko, and Christopher P Childers

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Surgical Interventions for Advanced Parameningeal Rhabdomyosarcoma of Children and Adolescents., Paul J Choi, Joe Iwanaga, R Shane Tubbs, and Emre Yilmaz

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Emerging Cellular Therapies for Glioblastoma Multiforme., Paul J Choi, R Shane Tubbs, and Rod J Oskouian

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Rates of Prevalent Colorectal Cancer Occurrence in Persons 75 Years of Age and Older: A Population-Based National Study., Vijit Chouhan, Emad Mansoor, Sravanthi Parasa, and Gregory S Cooper

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Implementation of an integrated computerized prescriber order-entry system for chemotherapy in a multisite safety-net health system., Clement Chung, Shital Patel, Rosetta Lee, Lily Fu, Sean Reilly, Tuyet Ho, Jason Lionetti, Michael D George, and Pam Taylor

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A multi-center phase II study of high dose interleukin-2 sequenced with vemurafenib in patients with BRAF-V600 mutation positive metastatic melanoma., Joseph I Clark, Jatinder Singh, Marc S Ernstoff, Christopher D Lao, Lawrence E Flaherty, Theodore F Logan, Brendan Curti, Sanjiv S Agarwala, Bret Taback, Lee Cranmer, Jose Lutzky, Theresa L Luna, Sandra Aung, and David H Lawson

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Balancing the benefits and harms of thyroid cancer surveillance in survivors of Childhood, adolescent and young adult cancer: Recommendations from the international Late Effects of Childhood Cancer Guideline Harmonization Group in collaboration with the PanCareSurFup Consortium., S C Clement, L C M Kremer, F A Verburg, J H Simmons, M Goldfarb, R P Peeters, E K Alexander, E Bardi, E Brignardello, L S Constine, C A Dinauer, V M Drozd, F Felicetti, E Frey, A Heinzel, M M van den Heuvel-Eibrink, S A Huang, T P Links, K Lorenz, R L Mulder, S J Neggers, E J M Nieveen van Dijkum, K C Oeffinger, R R van Rijn, S A Rivkees, C M Ronckers, A B Schneider, R Skinner, J D Wasserman, T Wynn, M M Hudson, P C Nathan, and H M van Santen

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An early feasibility study of the Nativis Voyager, Charles Cobbs, Edward McClay, J Paul Duic, L Burt Nabors, Donna Morgan Murray, and Santosh Kesari

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Safety and efficacy of pomalidomide, dexamethasone and pegylated liposomal doxorubicin for patients with relapsed or refractory multiple myeloma., Alexa Cohen, Tanya M Spektor, Laura Stampleman, Alberto Bessudo, Peter J Rosen, Leonard M Klein, Thomas Woliver, Marshall Flam, Shahrooz Eshaghian, Youram Nassir, Tina Maluso, Regina A Swift, Robert Vescio, and James R Berenson

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Evolution of the graded repair of CSF leaks and skull base defects in endonasal endoscopic tumor surgery: trends in repair failure and meningitis rates in 509 patients., Andrew Conger, Fan Zhao, Xiaowen Wang, Amy Eisenberg, Chester Griffiths, Felice Esposito, Ricardo L Carrau, Garni Barkhoudarian, and Daniel F Kelly

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Implementation and Validation of an Automated Flow Cytometry Analysis Pipeline for Human Immune Profiling., Valerie Conrad, Christopher Dubay, Mehrnoush Malek, Ryan R Brinkman, Yoshinobu Koguchi, and William L. Redmond

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Prediagnostic circulating markers of inflammation and risk of oesophageal adenocarcinoma: a study within the National Cancer Institute Cohort Consortium., Michael B Cook, Matthew J Barnett, Cathryn H Bock, Amanda J Cross, Phyllis J Goodman, Gary E Goodman, Christopher A Haiman, Kay-Tee Khaw, Marjorie L McCullough, Christine C Newton, Marie-Christine Boutron-Ruault, Eiliv Lund, Martin Rutegård, Mark D Thornquist, Michael Spriggs, Carol Giffen, Neal D Freedman, Troy Kemp, Candyce H Kroenke, Loïc Le Marchand, Jin Young Park, Michael Simon, Lynne R Wilkens, Ligia Pinto, Allan Hildesheim, and Peter T Campbell

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Delayed immune-related events after discontinuation of immunotherapy – DIRE syndrome?, Marcus Couey, R. Bryan Bell, Ashish Patel, Marka R Crittenden, Brendan Curti, and Rom Leidner

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Tumor cure by radiation therapy and checkpoint inhibitors depends on pre-existing immunity., Marka R Crittenden, Lauren Zebertavage, Gwen Kramer, Shelly Bambina, David Friedman, Victoria Troesch, Tiffany Blair, Jason R Baird, Alejandro F Alice, and Michael J Gough

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Immunotherapy in Advanced Renal Cancer - Is Cure Possible?, Brendan D Curti

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Rare but Recurrent ROS1 Fusions Resulting From Chromosome 6q22 Microdeletions are Targetable Oncogenes in Glioma., Monika A Davare, Jacob J Henderson, Anupriya Agarwal, Jacob P Wagner, Sudarshan R Iyer, Nameeta Shah, Randy Woltjer, Romel Somwar, Stephen W Gilheeney, Ana DeCarvalo, Tom Mikkelson, Erwin G Van Meir, Marc Ladanyi, and Brian J Druker

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Current Imaging Modalities Understage One-Third of Patients with Stage I Rectal Cancer: Implications for Treatment Selection., Ahmed Dehal, Amanda N Graff-Baker, Brooke Vuong, Daniel Nelson, Shu-Ching Chang, Melanie Goldfarb, and Anton J Bilchik

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Neoadjuvant Chemotherapy Improves Survival in Patients with Clinical T4b Colon Cancer., Ahmed N Dehal, Amanda N Graff-Baker, Brooke Vuong, Trevan Fischer, Samuel J Klempner, Shu-Ching Chang, Gary Grunkemeier, Anton J Bilchik, and Melanie Goldfarb

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Correlation Between Clinical and Pathologic Staging in Colon Cancer: Implications for Neoadjuvant Treatment., Ahmed N Dehal, Amanda N Graff-Baker, Brooke Vuong, Daniel Nelson, Shu-Ching Chang, David Y Lee, Melanie Goldfarb, and Anton J Bilchik

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Robot-assisted partial nephrectomy for large renal masses: a multi-institutional series., Joan C Delto, David Paulucci, Michael W Helbig, Ketan K Badani, Daniel Eun, James Porter, Ronney Abaza, Ashok K Hemal, and Akshay Bhandari

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The Role of Precision Medicine in the Diagnosis and Treatment of Patients with Rare Cancers., Michael J Demeure

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Modified carbazoles destabilize microtubules and kill glioblastoma multiform cells., Philippe Diaz, Eric Horne, Cong Xu, Ernest Hamel, Michael Wagenbach, Ravil R Petrov, Benjamin Uhlenbruck, Brian Haas, Parvinder Hothi, Linda Wordeman, Rick Gussio, and Nephi Stella

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Randomized phase II trial of autologous dendritic cell vaccines versus autologous tumor cell vaccines in metastatic melanoma: 5-year follow up and additional analyses., Robert O. Dillman, Andrew N Cornforth, Gabriel I Nistor, Edward F McClay, Thomas T Amatruda, and Carol Depriest

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Digitizing omics profiles by divergence from a baseline., Wikum Dinalankara, Qian Ke, Yiran Xu, Lanlan Ji, Nicole Pagane, Anching Lien, Tejasvi Matam, Elana J Fertig, Nathan D Price, Laurent Younes, Luigi Marchionni, and Donald Geman

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Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics., Li Ding, Matthew H Bailey, Eduard Porta-Pardo, Vesteinn Thorsson, Antonio Colaprico, Denis Bertrand, David L Gibbs, Amila Weerasinghe, Kuan-Lin Huang, Collin Tokheim, Isidro Cortés-Ciriano, Reyka Jayasinghe, Feng Chen, Lihua Yu, Sam Sun, Catharina Olsen, Jaegil Kim, Alison M Taylor, Andrew D Cherniack, Rehan Akbani, Chayaporn Suphavilai, Niranjan Nagarajan, Joshua M Stuart, Gordon B Mills, Matthew A Wyczalkowski, Benjamin G Vincent, Carolyn M Hutter, Jean Claude Zenklusen, Katherine A Hoadley, Michael C Wendl, Llya Shmulevich, Alexander J Lazar, David A Wheeler, and Gad Getz

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Recent Approvals in Immunotherapy Options for Patients with Lung Cancer, Lavinia Dobrea and Timothy E. Byun

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Navigating the Complex Terrain of Clinical Trials, Lavinia Dobrea and Lucy Gansauer

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The Navigator's Role in Supporting Clinical Trials, Lavinia Dobrea and Lucy J. Gansauer

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Polyethyleneimine modification of aluminum hydroxide nanoparticle enhances antigen transportation and cross-presentation of dendritic cells., Heng Dong, Zhi-Fa Wen, Lin Chen, Na Zhou, Hui Liu, Shiling Dong, Hong-Ming Hu, and Yongbin Mou

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Co-expression of CD39 and CD103 identifies tumor-reactive CD8 T cells in human solid tumors., Thomas Duhen, Rebekka Duhen, Ryan Montler, Jake Moses, Tarsem Moudgil, Noel F de Miranda, Cheri P Goodall, Tiffany C Blair, Bernard A Fox, Jason E McDermott, Shu-Ching Chang, Gary Grunkemeier, Rom Leidner, Richard Bryan Bell, and Andrew D Weinberg

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Earle A. Chiles Research Institute 2017 Year In Review, Earle A. Chiles Research Institute

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Overcoming Tumor-Induced Immune Suppression: From Relieving Inhibition to Providing Costimulation with T Cell Agonists., Dana A Emerson and William L Redmond

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Correlation between Surgeon's assessment and radiographic evaluation of residual disease in women with advanced stage ovarian cancer reported to have undergone optimal surgical cytoreduction: An NRG Oncology/Gynecologic Oncology Group study., Ramez N Eskander, James Kauderer, Krishnansu S Tewari, Robert S Mannel, Robert E Bristow, David M O'Malley, Stephen C Rubin, Gretchen E Glaser, Chad A Hamilton, Keiichi Fujiwara, Warner K Huh, Frederick Ueland, Jean-Marie Stephan, and Robert A Burger

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Multiplatform profiling of meningioma provides molecular insight and prioritization of drug targets for rational clinical trial design., Richard G Everson, Yuuri Hashimoto, Jacob L Freeman, Tiffany R Hodges, Jason Huse, Shouhao Zhou, Joanne Xiu, David Spetzler, Nader Sanai, Lyndon Kim, Santosh Kesari, Andrew Brenner, Franco De Monte, Amy Heimberger, and Shaan M Raza

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The role of Galectin-3 in modulating tumor growth and immunosuppression within the tumor microenvironment., Mohammad Farhad, Annah S Rolig, and William L Redmond

Defining recurrence surveillance in typical and atypical pulmonary carcinoid, AF Feczko, CL Wilshire, and See all authors in comments

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Endoscopic Resection in the Esophagus., Andrew F Feczko and Brian E Louie

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Profiles of Brain Metastases: Prioritization of Therapeutic Targets., Sherise D Ferguson, Siyuan Zheng, Joanne Xiu, Shouhao Zhou, Mustafa Khasraw, Priscilla K Brastianos, Santosh Kesari, Jethro Hu, Jeremy Rudnick, Michael E Salacz, David Piccioni, Suyun Huang, Michael A Davies, Isabella C Glitza, John V Heymach, Jianjun Zhang, Nuhad K Ibrahim, John F DeGroot, Joseph McCarty, Barbara J O'Brien, Raymond Sawaya, Roeland G W Verhaak, Sandeep K Reddy, Waldemar Priebe, Zoran Gatalica, David Spetzler, and Amy B Heimberger

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Ependymomas overexpress chemoresistance and DNA repair-related proteins., Sherise D Ferguson, Shouhao Zhou, Joanne Xiu, Yuuri Hashimoto, Nader Sanai, Lyndon Kim, Santosh Kesari, John de Groot, David Spetzler, and Amy B Heimberger

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Fine mapping of MHC region in lung cancer highlights independent susceptibility loci by ethnicity., Aida Ferreiro-Iglesias, Corina Lesseur, James McKay, Rayjean J Hung, Younghun Han, Xuchen Zong, David Christiani, Mattias Johansson, Xiangjun Xiao, Yafang Li, David C Qian, Xuemei Ji, Geoffrey Liu, Neil Caporaso, Ghislaine Scelo, David Zaridze, Anush Mukeriya, Milica Kontic, Simona Ognjanovic, Jolanta Lissowska, Małgorzata Szołkowska, Beata Swiatkowska, Vladimir Janout, Ivana Holcatova, Ciprian Bolca, Milan Savic, Miodrag Ognjanovic, Stig Egil Bojesen, Xifeng Wu, Demetrios Albanes, Melinda C Aldrich, Adonina Tardon, Ana Fernandez-Somoano, Guillermo Fernandez-Tardon, Loic Le Marchand, Gadi Rennert, Chu Chen, Jennifer Doherty, Gary Goodman, Heike Bickeböller, H-Erich Wichmann, Angela Risch, Albert Rosenberger, Hongbing Shen, Juncheng Dai, John K Field, Michael Davies, Penella Woll, M Dawn Teare, Lambertus A Kiemeney, Erik H F M van der Heijden, Jian-Min Yuan, Yun-Chul Hong, Aage Haugen, Shanbeh Zienolddiny, Stephen Lam, Ming-Sound Tsao, Mikael Johansson, Kjell Grankvist, Matthew B Schabath, Angeline Andrew, Eric Duell, Olle Melander, Hans Brunnström, Philip Lazarus, Susanne Arnold, Stacey Slone, Jinyoung Byun, Ahsan Kamal, Dakai Zhu, Maria Teresa Landi, Christopher I Amos, and Paul Brennan

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Pediatric-protocol of multimodal therapy is associated with improved survival in AYAs and adults with rhabdomyosarcoma., Trevan D Fischer, Shrawan G Gaitonde, Bradley C Bandera, Mehul V Raval, Sanjeev A Vasudevan, Kenneth W Gow, Elizabeth A Beierle, John J Doski, Adam B Goldin, Monica Langer, Jed G Nuchtern, Stacey Stern, Leland J Foshag, and Melanie Goldfarb

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The Negative Impact of Body Mass Index on the Tumor Microenvironment in Colon Cancer: Results of a Prospective Trial., Devin C Flaherty, John R Jalas, Myung S Sim, Alexander Stojadinovic, Mladjan Protic, Delphine J Lee, and Anton J Bilchik

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Driver Fusions and Their Implications in the Development and Treatment of Human Cancers., Qingsong Gao, Wen-Wei Liang, Steven M Foltz, Gnanavel Mutharasu, Reyka G Jayasinghe, Song Cao, Wen-Wei Liao, Sheila M Reynolds, Matthew A Wyczalkowski, Lijun Yao, Lihua Yu, Sam Q Sun, Ken Chen, Alexander J Lazar, Ryan C Fields, Michael C Wendl, Brian A Van Tine, Ravi Vij, Feng Chen, Matti Nykter, Ilya Shmulevich, and Li Ding

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Tumor cell-released autophagosomes (TRAP) enhance apoptosis and immunosuppressive functions of neutrophils., Rong Gao, Jie Ma, Zhifa Wen, Peiying Yang, Jinjin Zhao, Meng Xue, Yongqiang Chen, Mohanad Aldarouish, Hong-Ming Hu, Xue-Jun Zhu, Ning Pan, and Li-Xin Wang

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Randomized phase II study of fulvestrant and erlotinib compared with erlotinib alone in patients with advanced or metastatic non-small cell lung cancer., Edward B Garon, Jill M Siegfried, Laura P Stabile, Patricia A Young, Diana C Marquez-Garban, David J Park, Ravi Patel, Eddie H Hu, Saeed Sadeghi, Rupesh J Parikh, Karen L Reckamp, Brad Adams, Robert M Elashoff, David Elashoff, Tristan Grogan, He-Jing Wang, Sanja Dacic, Meghan Brennan, Yacgley Valdes, Simon Davenport, Steven M Dubinett, Michael F Press, Dennis J Slamon, and Richard J Pietras

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Pathologists' Use of Second Opinions in Interpretation of Melanocytic Cutaneous Lesions: Policies, Practices, and Perceptions., Berta M Geller, Paul D Frederick, Stevan R Knezevich, Jason P Lott, Heidi D Nelson, Linda J Titus, Patricia A Carney, Anna N A Tosteson, Tracy L Onega, Raymond L Barnhill, Martin A Weinstock, David E Elder, Michael W Piepkorn, and Joann G Elmore

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Voxel-Wise Analysis of Fluoroethyltyrosine PET and MRI in the Assessment of Recurrent Glioblastoma During Antiangiogenic Therapy., Elizabeth George, Marie F Kijewski, Shipra Dubey, Anthony P Belanger, David A Reardon, Patrick Y Wen, Santosh Kesari, Laura Horky, Mi-Ae Park, and Raymond Y Huang

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Randomized phase III study of docetaxel plus bavituximab in previously treated advanced non-squamous non-small-cell lung cancer., D E Gerber, L Horn, M Boyer, Rachel E Sanborn, R Natale, R Palmero, P Bidoli, I Bondarenko, P Germonpre, D Ghizdavescu, A Kotsakis, H Lena, G Losonczy, K Park, W-C Su, M Tang, J Lai, N L Kallinteris, J S Shan, M Reck, and D R Spigel

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A Placebo-Controlled Phase II Study of Ruxolitinib in Combination With Pemetrexed and Cisplatin for First-Line Treatment of Patients With Advanced Nonsquamous Non-Small-Cell Lung Cancer and Systemic Inflammation., Giuseppe Giaccone, Rachel E Sanborn, Saiama N Waqar, Alex Martinez-Marti, Santiago Ponce, Huiling Zhen, Gerard Kennealey, Susan Erickson-Viitanen, and Eric Schaefer

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The Impact of the ASAP Trial: Maybe We Shouldn't Act So Quickly., Christopher R Gilbert, Jason A Akulian, and Jed A Gorden

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The decision to biopsy in a lung cancer screening program: Potential impact of risk calculators., Christopher R Gilbert, Alexander S Carlson, Candice L Wilshire, Ralph W Aye, Alexander S Farivar, Adam J Bograd, and Jed A Gorden

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The economic impact of a nurse practitioner-directed lung cancer screening, incidental pulmonary nodule, and tobacco-cessation clinic., Christopher R Gilbert, Rob Ely, Joelle T Fathi, Brian E Louie, Candice L Wilshire, Hannah Modin, Ralph W Aye, Alexander S Farivar, Eric Vallières, and Jed A Gorden

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Impact of latency time on survival for adolescents and young adults with a second primary malignancy., Melanie Goldfarb, Aaron S Rosenberg, Qian Li, and Theresa H M Keegan

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TP73 DNA methylation and upregulation of ΔNp73 are associated with an adverse prognosis in breast cancer, Laura C Gomez, Mayra L Sottile, Martin E Guerrero-Gimenez, Felipe C M Zoppino, Analia L Redondo, Francisco E Gago, Javier I Orozco, Olga M Tello, Maria Roqué, Silvina B Nadin, Diego M Marzese, and Laura M Vargas-Roig

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Oncofertility in the setting of advanced cervical cancer - A case report., Catherine Gordon, Joseph C Carmichael, and Krishnansu S Tewari

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Implantable biomaterials to provide local immunotherapy following surgical resection., Michael J Gough, Jason R Baird, and R Bryan Bell

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Inducible T cell Co-stimulator (ICOS) is upregulated on lymphocytes following radiation of tumors and ICOS agonism in combination with radiation results in enhanced tumor control, Michael J. Gough, Shelly Bambina, Monica Gostissa, Christopher Harvey, David Friedman, and Marka R Crittenden

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Leptomeningeal Metastases., Jerome J Graber and Santosh Kesari

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Epigenomic and Transcriptomic Characterization of Secondary Breast Cancers., Amanda N Graff-Baker, Javier I Orozco, Diego M Marzese, Matthew P Salomon, Dave S B Hoon, and Melanie Goldfarb

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TumorNext-Lynch-MMR: a comprehensive next generation sequencing assay for the detection of germline and somatic mutations in genes associated with mismatch repair deficiency and Lynch syndrome., Phillip N Gray, Pei Tsai, Daniel Chen, Sitao Wu, Jayne Hoo, Wenbo Mu, Bing Li, Huy Vuong, Hsiao-Mei Lu, Navanjot Batth, Sara Willett, Lisa Uyeda, Swati Shah, Chia-Ling Gau, Monalyn Umali, Carin Espenschied, Mike Janicek, Sandra Brown, David Margileth, Lavinia Dobrea, Lawrence Wagman, Huma Rana, Michael J Hall, Theodora Ross, Jonathan Terdiman, Carey Cullinane, Savita Ries, Ellen Totten, and Aaron M Elliott

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Challenges to Educating Smokers About Lung Cancer Screening: a Qualitative Study of Decision Making Experiences in Primary Care., Preston A Greene, George Sayre, Jaimee L Heffner, Deborah E Klein, Paul Krebs, David H Au, and Steven B Zeliadt

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Phase II Feasibility Study of a Weight Loss Intervention in Female Breast and Colorectal Cancer Survivors (SWOG S1008)., Heather Greenlee, Danika L Lew, Dawn L Hershman, Vicky A Newman, Lisa Hansen, Sheri J Hartman, Judith Korner, Zaixing Shi, Christine L Sardo Molmenti, Antoine Sayegh, Lou Fehrenbacher, Shelly Lo, Jennifer Klemp, Kristine Rinn, John M Robertson, Joseph Unger, Julie Gralow, Kathy Albain, Robert Krouse, and Carol Fabian

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Clinical trial experience with CA4P anticancer therapy: focus on efficacy, cardiovascular adverse events, and hypertension management., Rachel Grisham, Bonnie Ky, Krishnansu S Tewari, David J Chaplin, and Joan Walker

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Loss of inter-cellular cooperation by complete epithelial-mesenchymal transition supports favorable outcomes in basal breast cancer patients., Anne Grosse-Wilde, Rolf E Kuestner, Stephanie M Skelton, Ellie MacIntosh, Aymeric Fouquier d'Hérouël, Gökhan Ertaylan, Antonio Del Sol, Alexander Skupin, and Sui Huang

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Aberrant Lck Signal via CD28 Costimulation Augments Antigen-Specific Functionality and Tumor Control by Redirected T Cells with PD-1 Blockade in Humanized Mice., Pratiksha Gulati, Julia Rühl, Abhilash Kannan, Magdalena Pircher, Petra Schuberth, Katarzyna J Nytko, Martin Pruschy, Simon Sulser, Mark Haefner, Shawn Jensen, Alex Soltermann, Wolfgang Jungraithmayr, Maya Eisenring, Thomas Winder, Panagiotis Samaras, Annett Tabor, Rene Stenger, Roger Stupp, Walter Weder, Christoph Renner, Christian Münz, and Ulf Petrausch

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Exploring optimal sequencing of radiation and immunotherapy combinations., Andrew J Gunderson and Kristina H Young

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Plasma vs Tissue Next-Generation Sequencing in Non-Small Cell Lung Cancer-Either, Both, or Neither?, Bishal Gyawali and Howard Jack West

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Regional Thoracic Surgery Quality Collaboration Formation: Providence Thoracic Surgery Initiative., John R Handy, Kimberly Costas, Robert McKenna, Steven Nisco, Raymond Schaerf, Kenton Stephens, Eric Vallières, Kasia Konieczny, Roshanthi Weerasinghe, Mansen Wang, Katherine Lothrop, and Cathy Betzer

Where's the Money? Revenues associated with 3000 Lung Cancer Screens, John Handy Jr., Courtney Wood, Erika Rauch, Kevin Olson, Roshanthi Weerasinghe, Rachel Sanborn, and Micheal Skokan

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Expert Consensus Document on Pulmonary Metastasectomy., J R Handy, R M Bremner, T S Crocenzi, F C Detterbeck, H C Fernando, P M Fidias, S Firestone, C A Johnstone, M Lanuti, V R Litle, K A Kesler, J D Mitchell, H I Pass, H J Ross, and T K Varghese

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Prognostic Value of ACVRL1 Expression in Metastatic Colorectal Cancer Patients Receiving First-line Chemotherapy With Bevacizumab: Results From the Triplet Plus Bevacizumab (TRIBE) Study., Diana L Hanna, Fotios Loupakis, Dongyun Yang, Chiara Cremolini, Marta Schirripa, Meng Li, Satoshi Matsusaka, Martin D Berger, Yuji Miyamoto, Wu Zhang, Yan Ning, Carlotta Antoniotti, Lisa Salvatore, Miriana Moran, Gary Zeger, Stephanie H Astrow, Alfredo Falcone, and Heinz-Josef Lenz

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Meta-Analysis of Local Invasive Breast Cancer Recurrence After Electron Intraoperative Radiotherapy., Jay K Harness, Kalatu Davies, Christina Via, Elizabeth Brooks, April Zambelli-Weiner, Chirag Shah, and Frank Vicini

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ASO Author Reflections: Meta-Analysis of Local Recurrence of Invasive Breast Cancer After Electron Intraoperative Radiotherapy., Jay K Harness and Chirag Shah

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Expression of LC3B and FIP200/Atg17 in brain metastases of breast cancer., Nooshin Hashemi-Sadraei, Gaëlle M Müller-Greven, Fadi W Abdul-Karim, Ilya Ulasov, Erinn Downs-Kelly, Monica E Burgett, Adam Lauko, Maha A Qadan, Robert J Weil, Manmeet S Ahluwalia, Lingling Du, Richard A Prayson, Samuel T Chao, Thomas G Budd, Jill Barnholtz-Sloan, Amy S Nowacki, Ruth A Keri, and Candece L Gladson

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Rethinking medulloblastoma from a targeted therapeutics perspective., Yuuri Hashimoto, Marta Penas-Prado, Shouhao Zhou, Jun Wei, Soumen Khatua, Tiffany R Hodges, Nader Sanai, Joanne Xiu, Zoran Gatalica, Lyndon Kim, Santosh Kesari, Ganesh Rao, David Spetzler, and Amy Heimberger

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Smokers' Inaccurate Beliefs about the Benefits of Lung Cancer Screening., Jaimee L Heffner, Paul Krebs, Hannah Johnson, Preston A Greene, Deborah E Klein, Laura C Feemster, Christopher G Slatore, David H Au, and Steven B Zeliadt

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Catheter-Related Thrombosis in Patients with Lymphoma or Myeloma Undergoing Autologous Stem Cell Transplantation., Livia Hegerova, Adam Bachan, Qing Cao, Huong X Vu, John Rogosheske, Mark T Reding, Claudio G Brunstein, Mukta Arora, Celalettin Ustun, Gregory M Vercellotti, and Veronika Bachanova

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Mindfulness-Based Interventions for Hematology and Oncology Patients with Pain., Denise Hess

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Integrative Molecular Characterization of Malignant Pleural Mesothelioma., Julija Hmeljak, Francisco Sanchez-Vega, Katherine A Hoadley, Juliann Shih, Chip Stewart, David Heiman, Patrick Tarpey, Ludmila Danilova, Esther Drill, Ewan A Gibb, Reanne Bowlby, Rupa Kanchi, Hatice U Osmanbeyoglu, Yoshitaka Sekido, Jumpei Takeshita, Yulia Newton, Kiley Graim, Manaswi Gupta, Carl M Gay, Lixia Diao, David L Gibbs, Vesteinn Thorsson, Lisa Iype, Havish Kantheti, David T Severson, Gloria Ravegnini, Patrice Desmeules, Achim A Jungbluth, William D Travis, Sanja Dacic, Lucian R Chirieac, Françoise Galateau-Sallé, Junya Fujimoto, Aliya N Husain, Henrique C Silveira, Valerie W Rusch, Robert C Rintoul, Harvey Pass, Hedy Kindler, Marjorie G Zauderer, David J Kwiatkowski, Raphael Bueno, Anne S Tsao, Jenette Creaney, Tara Lichtenberg, Kristen Leraas, Jay Bowen, Ina Felau, Jean Claude Zenklusen, Rehan Akbani, Andrew D Cherniack, Lauren A Byers, Michael S Noble, Jonathan A Fletcher, A Gordon Robertson, Ronglai Shen, Hiroyuki Aburatani, Bruce W Robinson, Peter Campbell, and Marc Ladanyi

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Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer., Katherine A Hoadley, Christina Yau, Toshinori Hinoue, Denise M Wolf, Alexander J Lazar, Esther Drill, Ronglai Shen, Alison M Taylor, Andrew D Cherniack, Vésteinn Thorsson, Rehan Akbani, Reanne Bowlby, Christopher K Wong, Maciej Wiznerowicz, Francisco Sanchez-Vega, A Gordon Robertson, Barbara G Schneider, Michael S Lawrence, Houtan Noushmehr, Tathiane M Malta, Joshua M Stuart, Christopher C Benz, and Peter W Laird

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Early loss of Histone H2B monoubiquitylation alters chromatin accessibility and activates key immune pathways that facilitate progression of ovarian cancer., Jagmohan Hooda, Marian Novak, Matthew P Salomon, Chikako Matsuba, Romela I Ramos, Emily MacDuffie, Melissa Song, Michelle S Hirsch, Jenny Lester, Vinita Parkash, Beth Y Karlan, Moshe Oren, Dave S B Hoon, and Ronny Drapkin

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Ensartinib (X-396) in ALK-Positive Non-Small Cell Lung Cancer: Results from a First-in-Human Phase I/II, Multicenter Study., Leora Horn, Jeffrey R Infante, Karen L Reckamp, George R Blumenschein, Ticiana A Leal, Saiama N Waqar, Barbara J Gitlitz, Rachel E Sanborn, Jennifer G Whisenant, Liping Du, Joel W Neal, Jon P Gockerman, Gary Dukart, Kimberly Harrow, Chris Liang, James J Gibbons, Allison Holzhausen, Christine M Lovly, and Heather A Wakelee

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New and Important Changes in the TNM Staging System for Breast Cancer., Gabriel N Hortobagyi, Stephen B Edge, and Armando Giuliano

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Pathogenic Germline Variants in 10,389 Adult Cancers., Kuan-Lin Huang, R Jay Mashl, Yige Wu, Deborah I Ritter, Jiayin Wang, Clara Oh, Marta Paczkowska, Sheila Reynolds, Matthew A Wyczalkowski, Ninad Oak, Adam D Scott, Michal Krassowski, Andrew D Cherniack, Kathleen E Houlahan, Reyka Jayasinghe, Liang-Bo Wang, Daniel Cui Zhou, Di Liu, Song Cao, Young Won Kim, Amanda Koire, Joshua F McMichael, Vishwanathan Hucthagowder, Tae-Beom Kim, Abigail Hahn, Chen Wang, Michael D McLellan, Fahd Al-Mulla, Kimberly J Johnson, Olivier Lichtarge, Paul C Boutros, Benjamin Raphael, Alexander J Lazar, Wei Zhang, Michael C Wendl, Ramaswamy Govindan, Sanjay Jain, David Wheeler, Shashikant Kulkarni, John F Dipersio, Jüri Reimand, Funda Meric-Bernstam, Ken Chen, Ilya Shmulevich, Sharon E Plon, Feng Chen, and Li Ding

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Single cell sequencing to identify TCRs that recognize autologous tumor cells after vaccination with allogeinic DRibble vaccine, Hong-Ming Hu, Christopher C. Paustian, Zhifa Wen, Tarsem L. Moudgil, Traci L. Hilton, Sam Bookhardt, Guangjie Yu, Eric Tran, Venkatesh Rajamanickam, Walter Urba, Rachel E. Sanborn, and Bernard A. Fox

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Coordinated responses to individual tumor antigens by IgG antibody and CD8+ T cells following cancer vaccination., Tyler W Hulett, Shawn M. Jensen, Phillip A Wilmarth, Ashok P Reddy, Carmen Ballesteros-Merino, Michael E Afentoulis, Christopher Dubay, Larry L David, and Bernard A Fox

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Internal and External Validation of a 90-Day Percentage Erection Fullness Score Model Predicting Potency Recovery Following Robot-assisted Radical Prostatectomy., Linda M Huynh, Douglas Skarecky, Timothy Wilson, Clayon Lau, Christian Wagner, James R Porter, Jorn H Witt, and Thomas E Ahlering

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Protection from chemotherapy- and antibiotic-mediated dysbiosis of the gut microbiota by a probiotic with digestive enzymes supplement., Thomas E Ichim, Santosh Kesari, and Kim Shafer