The Cancer Institute is a leader in cutting-edge treatments. Using a truly multidisciplinary approach, patients have access to advanced diagnostics, minimally invasive surgical interventions, and personalized genomic and immune-oncologic treatment options. Our team of cancer specialists – many of whom completed fellowships and specialty training at prestigious academic centers – offers comprehensive services for individuals with a cancer diagnosis.

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Submissions from 2018

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Menopausal-Related Symptoms in Women One Year After Breast Cancer Surgery., Melissa Mazor, Kathryn Lee, Anand Dhruva, Janine K Cataldo, Steven M Paul, Michelle Melisko, Betty J Smoot, Jon D Levine, Charles Elboim, Yvette P Conley, and Christine Miaskowksi

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Assessment of local tissue water in the arms and trunk of breast cancer survivors with and without upper extremity lymphoedema., Melissa Mazor, Betty J Smoot, Judy Mastick, Grace Mausisa, Steven M Paul, Kord M Kober, Charles Elboim, Komal Singh, Yvette P Conley, Gabby Mickevicius, Jennifer Field, Heather Hutchison, and Christine Miaskowski

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Radiation recall myelitis following paclitaxel chemotherapy: The first reported case., Shearwood McClelland, Paul H Cooper, Anupama K Acheson, Jeremy N Ciporen, Jerry J Jaboin, and Timur Mitin

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Preoperative relative cerebral blood volume analysis in gliomas predicts survival and mitigates risk of biopsy sampling error., Brendan J McCullough, Valerie Ader, Brian Aguedan, Xu Feng, Daniel Susanto, Tara L Benkers, John W Henson, Marc Mayberg, Charles S Cobbs, Ryder P Gwinn, Stephen J Monteith, David W Newell, Johnny Delashaw, Sarah J Fouke, Steven Rostad, and Bart P Keogh

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Analysis and visualization of linked molecular and clinical cancer data by using Oncoscape., Lisa G McFerrin, Michael Zager, Jianan Zhang, Gretchen Krenn, Robert McDermott, Desert Horse-Grant, Emily Silgard, Kara Colevas, Paul Shannon, Hamid Bolouri, and Eric C Holland

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Multicenter Trial of Stereotactic Body Radiation Therapy for Low- and Intermediate-Risk Prostate Cancer: Survival and Toxicity Endpoints., Robert M Meier, Daniel A Bloch, Cristian Cotrutz, Alan C Beckman, George T Henning, Shermian A Woodhouse, Shirnett K Williamson, Najeeb Mohideen, John J Dombrowski, Robert L Hong, David G Brachman, Patrick W Linson, and Irving D Kaplan

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The safety and feasibility of minimally invasive sentinel lymph node staging using indocyanine green in the management of endometrial cancer., Alberto A Mendivil, Lisa N Abaid, John V Brown, Kristina M Mori, Tiffany L Beck, Howard D Epstein, John P Micha, and Bram H Goldstein

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The Impact of an Enhanced Recovery After Surgery Program on Patients Treated for Gynecologic Cancer in the Community Hospital Setting., Alberto A Mendivil, Justin R Busch, David C Richards, Heather Vittori, and Bram H Goldstein

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Human Gut Microbiota and Gastrointestinal Cancer., Changting Meng, Chunmei Bai, Thomas D Brown, Leroy E Hood, and Qiang Tian

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Is There a Role for VATS Sleeve Lobectomy in Lung Cancer?, Natalie N Merchant, Robert McKenna, and Osita Onugha

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Preliminary evaluation of a novel whole slide multispectral assessment of seven markers: Potential to minimize bias in the characterization of the tumor immune environment, Carmen Ballesteros Merino, Shawn Jensen, Carla Coltharp, Kristin Roman, Chichung Wang, Nikhil Lonberg, Sebastian Marwitz, Tarsem Moudgil, William Miller, William Redmond, Yoshinobu Koguchi, Carlo Bifulco, Clifford Hoyt, and Bernard A. Fox

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Targeting TWIST1 through loss of function inhibits tumorigenicity of human glioblastoma., Andrei M Mikheev, Svetlana A Mikheeva, Liza J Severs, Cory C Funk, Lei Huang, José L McFaline-Figueroa, Jeanette Schwensen, Cole Trapnell, Nathan D Price, Stephen Wong, and Robert C Rostomily

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Venous Flare Reactions: A Case Report of Reactions Following Etoposide Infusion., Jaya Mini Gill, Janice Frost, Rachelle Park, and Marlon G Saria

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Robotic retroperitoneal lymph node dissection for testicular cancer: feasibility and latest outcomes., Harsha R Mittakanti and James R Porter

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The GSK3 Signaling Axis Regulates Adaptive Glutamine Metabolism in Lung Squamous Cell Carcinoma., Milica Momcilovic, Sean T Bailey, Jason T Lee, Michael C Fishbein, Daniel Braas, James Go, Thomas G Graeber, Francesco Parlati, Susan Demo, Rui Li, Tonya C Walser, Michael Gricowski, Robert Shuman, Julio Ibarra, Deborah Fridman, Michael E Phelps, Karam Badran, Maie St John, Nicholas M Bernthal, Noah Federman, Jane Yanagawa, Steven M Dubinett, Saman Sadeghi, Heather R Christofk, and David B Shackelford

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The incidence of occult malignancy following uterine morcellation: A ten-year single institution experience retrospective cohort study., Kristina M Mori, Lisa N Abaid, Alberto A Mendivil, John V Brown, Tiffany L Beck, John P Micha, Howard D Epstein, and Bram H Goldstein

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Simulation Study of cDNA Dataset to Investigate Possible Association of Differentially Expressed Genes of Human THP1-Monocytic Cells in Cancer Progression Affected by Bacterial Shiga Toxins., Syed A Muhammad, Jinlei Guo, Thanh M Nguyen, Xiaogang Wu, Baogang Bai, X Frank Yang, and Jake Y Chen

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Antibody drug conjugates: Progress, pitfalls, and promises., Anubhab Mukherjee, Ariana K Waters, Ivan Babic, Elmar Nurmemmedov, Mark C Glassy, Santosh Kesari, and Venkata Mahidhar Yenugonda

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The contribution of cholesterol and epigenetic changes to the pathophysiology of breast cancer., Maliha T Munir, Christopher Ponce, Catherine A Powell, Kaiser Tarafdar, Teruyoshi Yanagita, Mahua Choudhury, Lauren S Gollahon, and Shaikh M Rahman

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Tucatinib with capecitabine and trastuzumab in advanced HER2-positive metastatic breast cancer with and without brain metastases: a non-randomised, open-label, phase 1b study., Rashmi Murthy, Virginia F Borges, Alison Conlin, Jorge Chaves, Marc Chamberlain, Todd Gray, Alex Vo, and Erika Hamilton

Strategies For Clinical Implementation: Precision Oncology At Three Distinct Institutions., Lincoln D Nadauld, James M Ford, Daryl Pritchard, and Thomas Brown

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How our Neuro-Oncology Team Provides Next-generation Cancer Care, Joy Nakhla, Viorela Pop, Lavinia Dobrea, Lawrence D. Wagman, and Lars Anker

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Sentinel node evaluation in prostate cancer., Ramkishen Narayanan and Timothy G Wilson

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Adjuvant Radiation is Associated with Improved Survival for Select Patients with Non-metastatic Adrenocortical Carcinoma., Daniel Nelson, Shu-Ching Chang, Brad C Bandera, Trevan D Fischer, Robert Wollman, and Melanie Goldfarb

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Adjuvant Radiation is Associated with Improved Survival for Select Patients with Non-metastatic Adrenocortical Carcinoma., Daniel Nelson, Shu-Ching Chang, Bradley Bandera, Trevan D Fischer, Robert Wollman, and Melanie Goldfarb

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Resectable Distal Pancreas Cancer: Time to Reconsider the Role of Upfront Surgery., Daniel W Nelson, Shu-Ching Chang, Gary Grunkemeier, Ahmed N Dehal, David Y Lee, Trevan D Fischer, L Andrew DiFronzo, and Victoria V O'Connor

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ASO Author Reflections: Incorporating Adjuvant Radiation into the Treatment Planning for Select Adrenocortical Carcinomas., Daniel W Nelson and Melanie Goldfarb

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Both the intratumoral immune and microbial microenvironment are linked to recurrence in human colon cancer: results from a prospective, multicenter nodal ultrastaging trial., Juliana Noguti, Alfred A Chan, Bradley Bandera, Colin J Brislawn, Mladjan Protic, Myung S Sim, Janet K Jansson, Anton J Bilchik, and Delphine J Lee

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Potent Immune Modulation by MEDI6383, an Engineered Human OX40 Ligand IgG4P Fc Fusion Protein., Michael D Oberst, Catherine Augé, Chad Morris, Stacy Kentner, Kathy Mulgrew, Kelly McGlinchey, James Hair, Shino Hanabuchi, Qun Du, Melissa Damschroder, Hui Feng, Steven Eck, Nicholas Buss, Lolke de Haan, Andrew J Pierce, Haesun Park, Andrew Sylwester, Michael K Axthelm, Louis Picker, Nicholas P Morris, Andrew D Weinberg, and Scott A Hammond

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Accuracy of Digital Pathologic Analysis vs Traditional Microscopy in the Interpretation of Melanocytic Lesions., Tracy Onega, Raymond L Barnhill, Michael W Piepkorn, Gary M Longton, David E Elder, Martin A Weinstock, Stevan R Knezevich, Lisa M Reisch, Patricia A Carney, Heidi D Nelson, Andrea C Radick, and Joann G Elmore

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Epigenetic profiling for the molecular classification of metastatic brain tumors., Javier I Orozco, Theo A Knijnenburg, Ayla O Manughian-Peter, Matthew P Salomon, Garni Barkhoudarian, John R Jalas, James S Wilmott, Parvinder Hothi, Xiaowen Wang, Yuki Takasumi, Michael E Buckland, John F Thompson, Georgina V Long, Charles S Cobbs, Ilya Shmulevich, Daniel F Kelly, Richard A Scolyer, Dave S B Hoon, and Diego M Marzese

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Second cycle remission achievement with 7+3 and survival in adults with newly diagnosed acute myeloid leukemia: analysis of recent SWOG trials., Megan Othus, Elihu H Estey, Guillermo Garcia-Manero, Brent L Wood, Derek L Stirewalt, John E Godwin, James K Weick, Jeanne E Anderson, Frederick R Appelbaum, Harry P Erba, and Roland B Walter

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Patient-reported outcomes in a phase II, North American study of alectinib in patients with ALK-positive, crizotinib-resistant, non-small cell lung cancer., Sai-Hong Ignatius Ou, Mark A Socinski, Shirish Gadgeel, Leena Gandhi, Howard West, Alberto Alejandro Chiappori, Victor Cohen, Gregory J Riely, Vlatka Smoljanovic, Walter Bordogna, Elaine Wright, Kendra Debusk, Ali Zeaiter, and Alice T Shaw

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Monosomy 17 in potentially curable HER2-amplified breast cancer: prognostic and predictive impact., David B Page, Hannah Wen, Edi Brogi, Dana Dure, Dara Ross, Kateri J Spinelli, Sujata Patil, Larry Norton, Clifford Hudis, and Heather L McArthur

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Updated efficacy of first or second-line pembrolizumab plus in metastatic triple negative breast cancer and correlations with baseline lymphocyte and naïve CD4+ T-cell count, David Page, Joanna Pucilowska, Laura Bennetts, I Kim, Katherine Sanchez, Maritza Martel, Alison Conlin, Nikki Moxon, Staci Mellinger, Anupama Acheson, K Kemmer, Z Mitri, J Vuky, J Ahn, C Abaya, T Manigault, R Basho, Walter Urba, and HL McArthur

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International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study., Franck Pagès, Bernhard Mlecnik, Florence Marliot, Gabriela Bindea, Fang-Shu Ou, Carlo Bifulco, Alessandro Lugli, Inti Zlobec, Tilman T Rau, Martin D Berger, Iris D Nagtegaal, Elisa Vink-Börger, Arndt Hartmann, Carol Geppert, Julie Kolwelter, Susanne Merkel, Robert Grützmann, Marc Van den Eynde, Anne Jouret-Mourin, Alex Kartheuser, Daniel Léonard, Christophe Remue, Julia Y Wang, Prashant Bavi, Michael H A Roehrl, Pamela S Ohashi, Linh T Nguyen, SeongJun Han, Heather L MacGregor, Sara Hafezi-Bakhtiari, Bradly G Wouters, Giuseppe V Masucci, Emilia K Andersson, Eva Zavadova, Michal Vocka, Jan Spacek, Lubos Petruzelka, Bohuslav Konopasek, Pavel Dundr, Helena Skalova, Kristyna Nemejcova, Gerardo Botti, Fabiana Tatangelo, Paolo Delrio, Gennaro Ciliberto, Michele Maio, Luigi Laghi, Fabio Grizzi, Tessa Fredriksen, Bénédicte Buttard, Mihaela Angelova, Angela Vasaturo, Pauline Maby, Sarah E Church, Helen K Angell, Lucie Lafontaine, Daniela Bruni, Carine El Sissy, Nacilla Haicheur, Amos Kirilovsky, Anne Berger, Christine Lagorce, Jeffrey P Meyers, Christopher Paustian, Zipei Feng, Carmen Ballesteros-Merino, Jeroen Dijkstra, Carlijn van de Water, Shannon van Lent-van Vliet, Nikki Knijn, Ana-Maria Mușină, Dragos-Viorel Scripcariu, Boryana Popivanova, Mingli Xu, Tomonobu Fujita, Shoichi Hazama, Nobuaki Suzuki, Hiroaki Nagano, Kiyotaka Okuno, Toshihiko Torigoe, Noriyuki Sato, Tomohisa Furuhata, Ichiro Takemasa, Kyogo Itoh, Prabhu S Patel, Hemangini H Vora, Birva Shah, Jayendrakumar B Patel, Kruti N Rajvik, Shashank J Pandya, Shilin N Shukla, Yili Wang, Guanjun Zhang, Yutaka Kawakami, Francesco M Marincola, Paolo A Ascierto, Daniel J Sargent, Bernard A Fox, and Jérôme Galon

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Imaging-Ambiguous Lesions of Meckel's Cave-Utility of Endoscopic Endonasal Transpterygoid Biopsy., Sheri K Palejwala, Fan Zhao, Kayla C Lanker, Walavan Sivakumar, Yuki Takasumi, Chester F Griffiths, Garni Barkhoudarian, and Daniel F Kelly

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Development and Validation of a Model to Determine Risk of Progression of Barrett's Esophagus to Neoplasia., Sravanthi Parasa, Sreekar Vennalaganti, Srinivas Gaddam, Prashanth Vennalaganti, Patrick Young, Neil Gupta, Prashanthi Thota, Brooks Cash, Sharad Mathur, Richard Sampliner, Fouad Moawad, David Lieberman, Ajay Bansal, Kevin F Kennedy, John Vargo, Gary Falk, Manon Spaander, Marco Bruno, and Prateek Sharma

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Targeted treatment of advanced ovarian cancer: spotlight on rucaparib., Diana C Pearre and Krishnansu S Tewari

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Reply to M. McKenzie et al., Harry Peled, Kathleen Bickel, and Christina Puchalski

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Prospective study of serial 18F-FDG PET and 18F-fluoride (18F-NaF) PET to predict time to skeletal related events, time-to-progression, and survival in patients with bone-dominant metastatic breast cancer., Lanell M Peterson, Janet O'Sullivan, Qian Vicky Wu, Alena Novakova-Jiresova, Isaac Jenkins, Jean H Lee, Andrew Shields, Susan Montgomery, Hannah M Linden, Julie R Gralow, Vijayakrishna K Gadi, Mark Muzi, Paul E Kinahan, David A Mankoff, and Jennifer M Specht

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Bevacizumab in Cervical Cancer: 5 Years After., Krista S Pfaendler, Marisa C Liu, and Krishnansu S Tewari

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Safety of commercial airflight in patients with brain tumors: a case series., Michelle Phillips, Marlon Garzo Saria, Amy Eisenberg, Daniel F Kelly, and Garni Barkhoudarian

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Efficacy and toxicity of therapy immediately after treatment with nivolumab in relapsed multiple myeloma., Matthew J Pianko, Samuel A Funt, David B Page, Deepika Cattry, Emma C Scott, Stephen M Ansell, Ivan M Borrello, Martin Gutierrez, Nikoletta Lendvai, Hani Hassoun, C Ola Landgren, and Alexander M Lesokhin

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Effectiveness of Subcutaneously Administered Leuprolide Acetate to Achieve Low Nadir Testosterone in Prostate Cancer Patients., Christopher M Pieczonka, Przemyslaw Twardowski, Joseph Renzulli, Jason Hafron, Deborah M Boldt-Houle, Stuart Atkinson, and Scott Eggener

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New Clues to Human Longevity, Brian D. Piening

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Impact of Specimen Heterogeneity on Biomarkers in Repository Samples from Patients with Acute Myeloid Leukemia: A SWOG Report., Era L Pogosova-Agadjanyan, Anna Moseley, Megan Othus, Frederick R Appelbaum, Thomas R Chauncey, I-Ming L Chen, Harry P Erba, John E Godwin, Min Fang, Kenneth J Kopecky, Alan F List, Galina L Pogosov, Jerald P Radich, Cheryl L Willman, Brent L Wood, Soheil Meshinchi, and Derek L Stirewalt

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Late stage tumor regression after PD-L1 blockade with a concurrent OX40 agonist., Fanny Polesso, Andrew D Weinberg, and Amy E Moran

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Percutaneous coronary intervention in cancer patients: a report of the prevalence and outcomes in the United States., Jessica E Potts, Cezar A Iliescu, Juan C Lopez Mattei, Sara C Martinez, Lene Holmvang, Peter Ludman, Mark A De Belder, Chun Shing Kwok, Muhammad Rashid, David L Fischman, and Mamas A Mamas

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An anatomic transcriptional atlas of human glioblastoma., Ralph B Puchalski, Nameeta Shah, Jeremy Miller, Rachel Dalley, Steve R Nomura, Jae-Guen Yoon, Kimberly A Smith, Michael Lankerovich, Darren Bertagnolli, Kris Bickley, Andrew F Boe, Krissy Brouner, Stephanie Butler, Shiella Caldejon, Mike Chapin, Suvro Datta, Nick Dee, Tsega Desta, Tim Dolbeare, Nadezhda Dotson, Amanda Ebbert, David Feng, Xu Feng, Michael Fisher, Garrett Gee, Jeff Goldy, Lindsey Gourley, Benjamin W Gregor, Guangyu Gu, Nika Hejazinia, John Hohmann, Parvinder Hothi, Robert Howard, Kevin Joines, Ali Kriedberg, Leonard Kuan, Chris Lau, Felix Lee, Hwahyung Lee, Tracy Lemon, Fuhui Long, Naveed Mastan, Erika Mott, Chantal Murthy, Kiet Ngo, Eric Olson, Melissa Reding, Zack Riley, David Rosen, David Sandman, Nadiya Shapovalova, Clifford R Slaughterbeck, Andrew Sodt, Graham Stockdale, Aaron Szafer, Wayne Wakeman, Paul E Wohnoutka, Steven J White, Don Marsh, Robert C Rostomily, Lydia Ng, Chinh Dang, Allan Jones, Bart Keogh, Haley R Gittleman, Jill S Barnholtz-Sloan, Patrick J Cimino, Megha S Uppin, C Dirk Keene, Farrokh R Farrokhi, Justin D Lathia, Michael E Berens, Antonio Iavarone, Amy Bernard, Ed Lein, John W Phillips, Steven W Rostad, Charles Cobbs, Michael J Hawrylycz, and Greg D Foltz

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Tumor infiltrating lymphocyte recruitment after peri-lymphatic IRX-2 cytokine immunotherapy in resectable breast cancer and head and neck carcinoma, Joanna Pucilowska, Venkatesh Rajamanickam, Nikki Moxon, Monil Shah, Maritza Martel, Alison Conlin, James E. Egan, and David B. Page

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Perilymphatic IRX-2 cytokine therapy to enhance tumor infiltrating lymphocytes and PD-L1 expression preceding curative-intent therapy in early stage breast cancer, Joanna Pucilowska, Venkatesh Rajamanickam, Katherine Sanchez, Valerie Conrad, Alison Conlin, Shagheyegh Aliabadi-Wahle, Shu-Ching Chang, Gary Grunkemeier, Nikki Moxon, Staci Mellinger, Maritza Martel, James Egan, Monil Shah, and David B Page

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The Integrated Genomic Landscape of Thymic Epithelial Tumors., Milan Radovich, Curtis R Pickering, Ina Felau, Gavin Ha, Hailei Zhang, Heejoon Jo, Katherine A Hoadley, Pavana Anur, Jiexin Zhang, Mike McLellan, Reanne Bowlby, Thomas Matthew, Ludmila Danilova, Apurva M Hegde, Jaegil Kim, Mark D M Leiserson, Geetika Sethi, Charles Lu, Michael Ryan, Xiaoping Su, Andrew D Cherniack, Gordon Robertson, Rehan Akbani, Paul Spellman, John N Weinstein, D Neil Hayes, Ben Raphael, Tara Lichtenberg, Kristen Leraas, Jean Claude Zenklusen, Junya Fujimoto, Cristovam Scapulatempo-Neto, Andre L Moreira, David Hwang, James Huang, Mirella Marino, Robert Korst, Giuseppe Giaccone, Yesim Gokmen-Polar, Sunil Badve, Arun Rajan, Philipp Ströbel, Nicolas Girard, Ming S Tsao, Alexander Marx, Anne S Tsao, and Patrick J Loehrer

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Reviewing the Risk of Colorectal Cancer in Inflammatory Bowel Disease After Liver Trasnplantation for Primary Sclerosing Cholangitis., Bhavana Bhagya Rao, Bret Lashner, and Kris V Kowdley

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Referrals for palliative care and hospice are underutilized in patients with advanced non-small cell lung cancer, JR Rayburn, Candice L. Wilshire, CR Gilbert, BE Louie, RW Aye, AS Farivar, E Vallières, and JA Gorden

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Multistate healthcare network underutilizes valuable end-of-life resources in stage IV non-small cell lung cancer, JR Rayburn, Candice L. Wilshire, CR Gilbert, RK Weerasinghe, BE Louie, RW Aye, AS Farivar, E Vallières, and JA Gorden

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Patterns of multidisciplinary tumor board utilization in the management of non-small cell lung cancer The American Thoracic Society San Diego, California, JR Rayburn, Candice L. Wilshire, and See all authors in comments

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Reducing the use of catheters, tubes and imaging after hiatal hernia surgery significantly reduces length of hospital stay Society of American Gastrointestinal and Endoscopic Surgeons Annual Meeting Seattle, Washington, JR Rayburn, Candice L. Wilshire, and See all authors in comments

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Performance status and resource utilization in patients receiving palliative with stage IV advanced non-small cell lung cancer The International Association for the Study of Lung Cancer 19th World Conferenc, J Rayburn, Candice L. Wilshire, Christopher R Gilbert, Roshanthi Weerasignhe, Brian Louie, Ralph W Aye, Alexander S Farivar, Eric Vallieres, and Jed A Gorden

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Chirping Rales in Hypersensitivity Pneumonitis., Jerome M Reich

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Reservations Regarding Lung Cancer Screening Guidelines., Jerome M Reich

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Sarcoidosis in WTC-Exposed workers., Jerome M Reich

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The Curious Omission of Treatment as a Predictor of Pulmonary Sarcoidosis Mortality., Jerome M Reich

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Erratum to inequivalence of non-aggressiveness in clinically diagnosed lung cancers and overdiagnosis in lung cancer screening trials., Jerome M Reich and Jong S Kim

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Pazopanib with low fat meal (PALM) in advanced renal cell carcinoma., Melissa A Reimers, Maryann M Shango, Stephanie Daignault-Newton, Rachel Dedinsky, Danielle Karsies, Shawna Kraft, Liam Riddle, Jeremy A Felton, Bo Wen, Christina Gersch, James M Rae, Bruce G Redman, and Ajjai S Alva

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What have we been trying to do and have we been any good at it? A history of measuring the success of genetic counseling., Robert G Resta

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Limitations in learning: How treatment verifications fail and what to do about it?, Susan Richardson and Bruce Thomadsen

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Adverse Events, Patterns of Tumor Lysis Syndrome Prophylaxis and Management, and Dosing Patterns in a Large Cohort of Venetoclax Treated CLL Patients in Community and Academic Settings, Lindsey E. Roeker, Neil Bailey, and See full list of authors in comments

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NKTR-214 (CD122-biased agonist) and NKTR-262 (TLR7/8 agonist) combination treatment pairs local innate immune activation with systemic CD8+ T cell expansion to enhance anti-tumor immunity, Annah S. Rolig, Daniel Rose, Saul Kivimäe, Deborah Charych, Werner Rubas, Jonathan Zalevsky, and William L. Redmond

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Genetic modifiers of radon-induced lung cancer risk: a genome-wide interaction study in former uranium miners., Albert Rosenberger, Rayjean J Hung, David C Christiani, Neil E Caporaso, Geoffrey Liu, Stig E Bojesen, Loic Le Marchand, Ch A Haiman, Demetrios Albanes, Melinda C Aldrich, Adonina Tardon, G Fernández-Tardón, Gad Rennert, John K Field, B Kiemeney, Philip Lazarus, Aage Haugen, Shanbeh Zienolddiny, Stephen Lam, Matthew B Schabath, Angeline S Andrew, Hans Brunnsstöm, Gary E Goodman, Jennifer A Doherty, Chu Chen, M Dawn Teare, H-Erich Wichmann, Judith Manz, Angela Risch, Thomas R Muley, Mikael Johansson, Paul Brennan, Maria Teresa Landi, Christopher I Amos, Beate Pesch, Georg Johnen, Thomas Brüning, Heike Bickeböller, and Maria Gomolka

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Comparison of Quality Oncology Practice Initiative Metrics in Solid Tumor Oncology Clinic With or Without Concomitant Supportive Oncology Consultation., Rachel Rosenblum, Ran Huo, Bethann Scarborough, Nathan Goldstein, and Cardinale B Smith

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MHC class I loaded ligands from breast cancer cell lines: A potential HLA-I-typed antigen collection., Dmitri V Rozanov, Nikita D Rozanov, Kami E Chiotti, Ashok Reddy, Phillip A Wilmarth, Larry L David, Seung W Cha, Sunghee Woo, Pavel Pevzner, Vineet Bafna, Gregory G Burrows, Juha K Rantala, Trevor Levin, Pavana Anur, Katie Johnson-Camacho, Shaadi Tabatabaei, Daniel J Munson, Tullia C Bruno, Jill E Slansky, John W Kappler, Naoto Hirano, Sebastian Boegel, Bernard A Fox, Colt Egelston, Diana L Simons, Grecia Jimenez, Peter P Lee, Joe W Gray, and Paul T Spellman

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Brain metastasis DNA methylomes, a novel resource for the identification of biological and clinical features., Matthew P Salomon, Javier I J Orozco, James S Wilmott, Parvinder Hothi, Ayla O Manughian-Peter, C Cobbs, Richard A Scolyer, Dave S B Hoon, and Diego M Marzese

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The Epigenomic Landscape of Pituitary Adenomas Reveals Specific Alterations and Differentiates Among Acromegaly, Cushing's Disease and Endocrine-Inactive Subtypes., Matthew P Salomon, Xiaowen Wang, Diego M Marzese, Sandy C Hsu, Nellie Nelson, Xin Zhang, Chikako Matsuba, Yuki Takasumi, Carmen Ballesteros-Merino, Bernard A Fox, Garni Barkhoudarian, Daniel F Kelly, and Dave S B Hoon

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Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images., Joel Saltz, Rajarsi Gupta, Le Hou, Tahsin Kurc, Pankaj Singh, Vu Nguyen, Dimitris Samaras, Kenneth R Shroyer, Tianhao Zhao, Rebecca Batiste, John Van Arnam, Ilya Shmulevich, Arvind U K Rao, Alexander J Lazar, Ashish Sharma, and Vésteinn Thorsson

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Preliminary results from a first-in-human phase 1 study of the CD40 agonist monoclonal antibody (mAb) CDX-1140, Rachel Sanborn, Michael S. Gordon, Mark O'Hara, Nina Bhardwaj, Yi He, Tracey Rawls, Tibor Keler, and Michael Yellin

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Oncogenic Signaling Pathways in The Cancer Genome Atlas., Francisco Sanchez-Vega, Marco Mina, Joshua Armenia, Walid K Chatila, Augustin Luna, Konnor C La, Sofia Dimitriadoy, David L Liu, Havish S Kantheti, Sadegh Saghafinia, Debyani Chakravarty, Foysal Daian, Qingsong Gao, Matthew H Bailey, Wen-Wei Liang, Steven M Foltz, Ilya Shmulevich, Li Ding, Zachary Heins, Angelica Ochoa, Benjamin Gross, Jianjiong Gao, Hongxin Zhang, Ritika Kundra, Cyriac Kandoth, Istemi Bahceci, Leonard Dervishi, Ugur Dogrusoz, Wanding Zhou, Hui Shen, Peter W Laird, Gregory P Way, Casey S Greene, Han Liang, Yonghong Xiao, Chen Wang, Antonio Iavarone, Alice H Berger, Trever G Bivona, Alexander J Lazar, Gary D Hammer, Thomas Giordano, Lawrence N Kwong, Grant McArthur, Chenfei Huang, Aaron D Tward, Mitchell J Frederick, Frank McCormick, Matthew Meyerson, Eliezer M Van Allen, Andrew D Cherniack, Giovanni Ciriello, Chris Sander, and Nikolaus Schultz

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Vitamin D3 decreases glycolysis and invasiveness, and increases cellular stiffness in breast cancer cells, Julianna Maria Santos, Zeina Shereen Khan, Maliha Tabassum Munir, Kaiser Tarafdar, Shaikh Mizanoor Rahman, and Fazle Hussain

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Poor outcome with hematopoietic stem cell transplantation for bone marrow failure and MDS with severe MIRAGE syndrome phenotype., Jay Sarthy, Ji Zha, Daria Babushok, Archana Shenoy, Jian-Meng Fan, Gerald Wertheim, Adam Himebauch, Ashley Munchel, Agne Taraseviciute, Samuel Yang, Hirohito Shima, Satoshi Narumi, Soheil Meshinchi, and Timothy S Olson

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Evolution of the mutational process under relaxed selection in Caenorhabditis elegans., Ayush Shekhar Saxena, Matthew P Salomon, Chikako Matsuba, Shu-Dan Yeh, and Charles F Baer

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Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas., Franz X Schaub, Varsha Dhankani, Ashton C Berger, Mihir Trivedi, Anne B Richardson, Reid Shaw, Wei Zhao, Xiaoyang Zhang, Andrea Ventura, Yuexin Liu, Donald E Ayer, Peter J Hurlin, Andrew D Cherniack, Robert N Eisenman, Brady Bernard, Carla Grandori, and Bernard Brady

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Telomerase reverse transcriptase promoter alterations across cancer types as detected by next-generation sequencing: A clinical and molecular analysis of 423 patients., Maria Schwaederle, Nithya Krishnamurthy, Gregory A Daniels, David E Piccioni, Santosh Kesari, Paul T Fanta, Richard B Schwab, Sandip P Patel, Barbara A Parker, and Razelle Kurzrock

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Impact of tumour histology on survival in advanced cervical carcinoma: an NRG Oncology/Gynaecologic Oncology Group Study., Leigh G Seamon, James J Java, Bradley J Monk, Richard T Penson, Jubilee Brown, Robert S Mannel, Anna Oaknin, Mario M Leitao, Eric L Eisenhauer, Harry J Long, Shu Y Liao, and Krishnansu S Tewari

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Editorial: frequency of surveillance and survival in hepatocellular carcinoma., N H Senussi and K V Kowdley

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The Ecstacy of Gold: Patent Expirations for Trastuzumab, Bevacizumab, Rituximab, and Cetuximab., Tasha R Serna-Gallegos, Christopher J La-Fargue, and Krishnansu S Tewari

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The Ecstacy of Gold: Patent Expirations for Trastuzumab, Bevacizumab, Rituximab, and Cetuximab, Tasha R. Serna-Gallegos, Christopher J. La-Fargue, and Krishnansu S Tewari

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Centromere protein F (CENPF), a microtubule binding protein, modulates cancer metabolism by regulating pyruvate kinase M2 phosphorylation signaling., Muhammad Shahid, Minyoung Lee, Honit Piplani, Allen M Andres, Bo Zhou, Austin Yeon, Minjung Kim, Hyung L Kim, and Jayoung Kim

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Large pseudoencapsulated subcutaneous angiomyxoma: Surgical management., Christine M Shaver, Steven E Kolker, and Richard G Bennett

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Integrated Molecular Characterization of Testicular Germ Cell Tumors., Hui Shen, Juliann Shih, Daniel P Hollern, Linghua Wang, Reanne Bowlby, Satish K Tickoo, Vésteinn Thorsson, Andrew J Mungall, Yulia Newton, Apurva M Hegde, Joshua Armenia, Francisco Sánchez-Vega, John Pluta, Louise C Pyle, Rohit Mehra, Victor E Reuter, Guilherme Godoy, Jeffrey Jones, Carl S Shelley, Darren R Feldman, Daniel O Vidal, Davor Lessel, Tomislav Kulis, Flavio M Cárcano, Kristen M Leraas, Tara M Lichtenberg, Denise Brooks, Andrew D Cherniack, Juok Cho, David I Heiman, Katayoon Kasaian, Minwei Liu, Michael S Noble, Liu Xi, Hailei Zhang, Wanding Zhou, Jean C ZenKlusen, Carolyn M Hutter, Ina Felau, Jiashan Zhang, Nikolaus Schultz, Gad Getz, Matthew Meyerson, Joshua M Stuart, Rehan Akbani, David A Wheeler, Peter W Laird, Katherine L Nathanson, Victoria K Cortessis, and Katherine A Hoadley

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Immunotherapy in metastatic urothelial carcinoma: focus on immune checkpoint inhibition., Arlene Siefker-Radtke and Brendan Curti

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Intraoperative Radiation Therapy (IORT): A Series of 1000 Tumors., Melvin J Silverstein, Melinda Epstein, Brian Kim, Kevin Lin, Sadia Khan, Lincoln Snyder, Lisa Guerra, Colleen Coleman, and Peter Chen

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Gastric hibernoma: a novel location and presentation of a rare tumor., Shane P Smith, Andrew F Feczko, Matias Mihura, Jey-Hsin Chen, and Alexander S Farivar

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Glioblastoma radiomics: can genomic and molecular characteristics correlate with imaging response patterns?, Michael H Soike, Emory R McTyre, Nameeta Shah, Ralph B Puchalski, Jordan A Holmes, Anna K Paulsson, Lance D Miller, Christina K Cramer, Glenn J Lesser, Roy E Strowd, William H Hinson, Ryan T Mott, Annette J Johnson, Hui-Wen Lo, Adrian W Laxton, Stephen B Tatter, Waldemar Debinski, and Michael D Chan

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Multimodality Therapy for N2 Non-Small Cell Lung Cancer: An Evolving Paradigm., Jonathan D Spicer, Jitesh B Shewale, David B Nelson, Kyle G Mitchell, Matthew J Bott, Eric Vallieres, Candice L. Wilshire, Ara A Vaporciyan, Stephen G Swisher, David R Jones, Gail E Darling, and Boris Sepesi

Pulmonary nodule resection characteristics: experience from lung cancer screening programs in a multi-state, community-based health care network The American Thoracic Society San Diego, California, KM Spiegel, Candice L. Wilshire, and See all authors in comments

Referrals for Lung Cancer Screening: frontline health care professional participation remains low in the community The American Thoracic Society San Diego, California, KM Spiegel, Candice L. Wilshire, and See all authors in comments

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Disparities in fertility-sparing surgery in adolescent and young women with stage I ovarian dysgerminoma., Laura L Stafman, Ilan I Maizlin, Matthew Dellinger, Kenneth W Gow, Melanie Goldfarb, Jed G Nuchtern, Monica Langer, Sanjeev A Vasudevan, John J Doski, Adam B Goldin, Mehul Raval, and Elizabeth A Beierle

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Combined anti-PD-1 and anti-LAG-3 checkpoint blockade enhances CD8+ TIL effector function while reducing Tregs leading to reduced immune suppression and improved overall survival, Elizabeth Sturgill, Courtney Mick, David Jenkins, Johanna Kaufmann, and William L. Redmond

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An update on the Society for Immunotherapy of Cancer consensus statement on tumor immunotherapy for the treatment of cutaneous melanoma: version 2.0., Ryan J Sullivan, Michael B Atkins, John M Kirkwood, Sanjiv S Agarwala, Joseph I Clark, Marc S Ernstoff, Leslie Fecher, Thomas F Gajewski, Brian Gastman, David H Lawson, Jose Lutzky, David F McDermott, Kim A Margolin, Janice M Mehnert, Anna C Pavlick, Jon M Richards, Krista M Rubin, William Sharfman, Steven Silverstein, Craig L Slingluff, Vernon K Sondak, Ahmad A Tarhini, John A Thompson, Walter J Urba, Richard L White, Eric D Whitman, F Stephen Hodi, and Howard L Kaufman

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Association of Immunologic Markers With Survival in Upfront Resectable Pancreatic Cancer., Ephraim S Tang, Philippa H Newell, Ronald F Wolf, Paul Daniel Hansen, Benjamin Cottam, Carmen Ballesteros-Merino, and Michael J Gough