The Cancer Institute is a leader in cutting-edge treatments. Using a truly multidisciplinary approach, patients have access to advanced diagnostics, minimally invasive surgical interventions, and personalized genomic and immune-oncologic treatment options. Our team of cancer specialists – many of whom completed fellowships and specialty training at prestigious academic centers – offers comprehensive services for individuals with a cancer diagnosis.

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Submissions from 2017

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D20 LUNG CANCER SCREENING: MOVING FROM POPULATION TO PERSON: Minority And Economically Disadvantaged High-Risk Populations Are Underrepresented In Both Centralized And Decentralized Lung Cancer Screening Models, CC Fuller, Candice L. Wilshire, BM McCall, Christopher R Gilbert, Joelle T Fathi, JR Handy, KE Costas, Brian Louie, Ralph W Aye, Alexander S Farivar, Eric Vallieres, and Jed A Gorden

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Sex-Specific Differences in Colon Cancer when Quality Measures Are Adhered to: Results from International, Prospective, Multicenter Clinical Trials., Shrawan G Gaitonde, Aviram Nissan, Mladjan Protić, Alexander Stojadinovic, Zev A Wainberg, David C Chen, and Anton J Bilchik

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Efficacy and Safety of Pembrolizumab in Patients Enrolled in KEYNOTE-030 in the United States: An Expanded Access Program., Tara C Gangadhar, Wen-Jen Hwu, Michael A Postow, Omid Hamid, Adil Daud, Roxana Dronca, Richard Joseph, Steven J O'Day, F S Hodi, Anna C Pavlick, Harriet Kluger, Romina P Oxborough, Aiming Yang, Mihaela Gazdoiu, Debra A Kush, Scot Ebbinghaus, and April K S Salama

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Genetic and Genomic Characterization of 462 Melanoma Patient-Derived Xenografts, Tumor Biopsies, and Cell Lines., Bradley Garman, Ioannis N Anastopoulos, Clemens Krepler, Patricia Brafford, Katrin Sproesser, Yuchao Jiang, Bradley Wubbenhorst, Ravi Amaravadi, Joseph Bennett, Marilda Beqiri, David Elder, Keith T Flaherty, Dennie T Frederick, Tara C Gangadhar, Michael Guarino, Dave S B Hoon, Giorgos Karakousis, Qin Liu, Nandita Mitra, Nicholas J Petrelli, Lynn Schuchter, Batool Shannan, Carol L Shields, Jennifer Wargo, Brandon Wenz, Melissa A Wilson, Min Xiao, Wei Xu, Xaiowei Xu, Xiangfan Yin, Nancy R Zhang, Michael A Davies, Meenhard Herlyn, and Katherine L Nathanson

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Effects of socioeconomic status on children with well-differentiated thyroid cancer., Evan F Garner, Ilan I Maizlin, Matthew B Dellinger, Kenneth W Gow, Melanie Goldfarb, Adam B Goldin, John J Doski, Monica Langer, Jed G Nuchtern, Sanjeev A Vasudevan, Mehul V Raval, and Elizabeth A Beierle

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Characteristics associated with requests by pathologists for second opinions on breast biopsies., Berta M Geller, Heidi D Nelson, Donald L Weaver, Paul D Frederick, Kimberly H Allison, Tracy Onega, Patricia A Carney, Anna N A Tosteson, and Joann G Elmore

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Low-Dose-Rate Brachytherapy Versus Cryotherapy in Low- and Intermediate-Risk Prostate Cancer., Matthew M Gestaut, Wendi Cai, Shilpa Vyas, Belur J Patel, Salman A Hasan, Yolanda MunozMaldonado, Niloyjyoti Deb, and Gregory Swanson

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A Cell-Surface Membrane Protein Signature for Glioblastoma., Dhimankrishna Ghosh, Cory C Funk, Juan Caballero, Nameeta Shah, Katherine Rouleau, John C Earls, Liliana Soroceanu, Greg Foltz, Charles Cobbs, Nathan D Price, and Leroy Hood

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P1.03-050 Outcomes after the Decision to Biopsy: Results from a Nurse Practitioner Run Multidisciplinary Lung Cancer Screening Program Topic: Screening, Christopher R Gilbert, Joelle T Fathi, Candice L. Wilshire, Brian Louie, Ralph W Aye, Alexander S Farivar, Eric Vallieres, and Jed A Gorden

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PS05.02 Outcomes of Radiotherapy and Endoscopic Airway Stenting for Central Airway Obstruction in Non-Small Cell Lung Cancer Topic: Pulmonology, Christopher R Gilbert, Candice L. Wilshire, V Mehta, T Barnett, and Jed A Gorden

The financial impact of a nurse practitioner directed lung cancer screening and tobacco related disease program, CR Gilbert, JT Fathi, RE Ely, HE Modin, Candice L. Wilshire, RW Aye, AS Farivar, BE Louie, E Vallières, and JA Gorden

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FDG-PET scanning has a limited role in the management of low and intermediate, CR Gilbert, Candice L. Wilshire, and See all authors in comments

Outcomes of radiotherapy and endoscopic airway stenting for central airway obstruction in non-small cell lung cancer International Association for the Study of Lung Cancer Multidisciplinary Symposium in Thoracic Oncology Chicago, Illinois, CR Gilbert, Candice L. Wilshire, and See all authors in comments

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Ureteroenteric anastomotic revision as initial management of stricture after urinary diversion., Greg E Gin, Nora H Ruel, Jaspreet S Parihar, Jonathan N Warner, Bertram E Yuh, Jonathan Yamzon, Timothy G Wilson, Clayton S Lau, and Kevin G Chan

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Chromosome 1q21.3 amplification is a trackable biomarker and actionable target for breast cancer recurrence., Jian Yuan Goh, Min Feng, Wenyu Wang, Gokce Oguz, Siti Maryam J M Yatim, Puay Leng Lee, Yi Bao, Tse Hui Lim, Panpan Wang, Wai Leong Tam, Annette R Kodahl, Maria B Lyng, Suman Sarma, Selena Y Lin, Alexander Lezhava, Yoon Sim Yap, Alvin S T Lim, Dave S B Hoon, Henrik J Ditzel, Soo Chin Lee, Ern Yu Tan, and Qiang Yu

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A View from the Plateau: Is There a Role for Allogeneic Stem Cell Transplantation in the Era of Highly Effective Therapies for Multiple Myeloma?, Damian J Green and William Bensinger

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Immunotherapy biomarkers 2016: overcoming the barriers., James L Gulley, Jay A Berzofsky, Marcus O Butler, Alessandra Cesano, Bernard A Fox, Sacha Gnjatic, Sylvia Janetzki, Shyam Kalavar, Vaios Karanikas, Samir N Khleif, Ilan Kirsch, Peter P Lee, Cristina Maccalli, Holden Maecker, Jeffrey Schlom, Barbara Seliger, Janet Siebert, David F Stroncek, Magdalena Thurin, Jianda Yuan, and Lisa H Butterfield

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A TNF-JNK-Axl-ERK signaling axis mediates primary resistance to EGFR inhibition in glioblastoma., Gao Guo, Ke Gong, Sonia Ali, Neha Ali, Shahzad Shallwani, Kimmo J Hatanpaa, Edward Pan, Bruce Mickey, Sandeep Burma, David H Wang, Santosh Kesari, Jann N Sarkaria, Dawen Zhao, and Amyn A Habib

Outcomes of radiotherapy and endoscopic airway stenting for central airway obstruction in non-small cell lung cancer The International Association for the Study of Lung Cancer 18th World Conference on Lung Cancer Yokohama, Japan, CA Henson, Candice L. Wilshire, and See all authors in comments

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In Reply: Refining Tumor Resection Techniques for Managing Inferior Pole Breast Malignancies., Dennis R Holmes and Melvin J Silverstein

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Intraoperative radiotherapy: Patient selection, management, and follow-up., Dennis R Holmes and Robert Zimmerman

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Intraoperative radiotherapy: Patient selection, management, and follow-up., Dennis R Holmes and Robert Zimmerman

Long-term impact of endoscopic thoracic sympathectomy on quality of life for patients with primary palmar hyperhidrosis, LC Horslen, Candice L. Wilshire, BE Louie, RW Aye, AS Farivar, and E Vallières

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Prognostic Value of Multiple Draining Lymph Node Basins in Melanoma: A Matched-Pair Analysis Based on the John Wayne Cancer Institute Experience., J Harrison Howard, Junko J Ozao-Choy, Jason M Hiles, Myung-Shin Sim, and Mark Faries

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Epigenetic Regulation of KPC1 Ubiquitin Ligase Affects the NF-κB Pathway in Melanoma., Yuuki Iida, Aaron Ciechanover, Diego M Marzese, Keisuke Hata, Matias Bustos, Shigeshi Ono, Jinhua Wang, Matthew P Salomon, Kevin Tran, Stella Lam, Sandy Hsu, Nellie Nelson, Yelena Kravtsova-Ivantsiv, Gordon B Mills, Michael A Davies, and Dave S B Hoon

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ANGPTL4 promotes the progression of cutaneous melanoma to brain metastasis., Sivan Izraely, Shlomit Ben-Menachem, Orit Sagi-Assif, Tsipi Meshel, Diego M Marzese, Shuichi Ohe, Inna Zubrilov, Metsada Pasmanik-Chor, Dave S B Hoon, and Isaac P Witz

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Predictors of responses to immune checkpoint blockade in advanced melanoma., N Jacquelot, M P Roberti, D P Enot, S Rusakiewicz, N Ternès, S Jegou, D M Woods, A L Sodré, M Hansen, Y Meirow, M Sade-Feldman, A Burra, S S Kwek, C Flament, M Messaoudene, C P M Duong, L Chen, B S Kwon, A C Anderson, V K Kuchroo, B Weide, F Aubin, C Borg, S Dalle, O Beatrix, M Ayyoub, B Balme, G Tomasic, A M Di Giacomo, M Maio, D Schadendorf, I Melero, B Dréno, A Khammari, R Dummer, M Levesque, Yoshinobu Koguchi, L Fong, M Lotem, M Baniyash, H Schmidt, I M Svane, G Kroemer, A Marabelle, S Michiels, A Cavalcanti, M J Smyth, J S Weber, A M Eggermont, and L Zitvogel

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Safety and Feasibility of Minimally Invasive Inguinal Lymph Node Dissection in Patients With Melanoma (SAFE-MILND): Report of a Prospective Multi-institutional Trial., James W Jakub, Alicia M Terando, Amod Sarnaik, Charlotte E Ariyan, Mark Faries, Sabino Zani, Heather B Neuman, Nabil Wasif, Jeffrey M Farma, Bruce J Averbook, Karl Y Bilimoria, Travis E Grotz, Jacob B Jake Allred, Vera J Suman, Mary Sue Brady, Douglas Tyler, Jeffrey D Wayne, and Heidi Nelson

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Does gated beam delivery impact delivery accuracy on an Elekta linac?, Mohammed Jermoumi, Roger Xie, Daliang Cao, David J Housley, and David M Shepard

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The Impact of Smoking on Sentinel Node Metastasis of Primary Cutaneous Melanoma., Maris S Jones, Peter C Jones, Stacey L Stern, David Elashoff, Dave S B Hoon, John Thompson, Nicola Mozzillo, Omgo E Nieweg, Dirk Noyes, Harald J Hoekstra, Jonathan S Zager, Daniel F Roses, Alessandro Testori, Brendon J Coventry, Mark B Smithers, Robert Andtbacka, Doreen Agnese, Erwin Schultz, Eddy C Hsueh, Mark Kelley, Schlomo Schneebaum, Lisa Jacobs, Tawnya Bowles, Mohammed Kashani-Sabet, Douglas Johnson, and Mark B Faries

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Is Pregnancy-Associated Melanoma Associated with Adverse Outcomes?, Maris S Jones, Jihey Lee, Stacey L Stern, and Mark Faries

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Analysis of 340 Patients with Solid Pseudopapillary Tumors of the Pancreas: A Closer Look at Patients with Metastatic Disease., Zeljka Jutric, Yelena Rozenfeld, Jan Grendar, Chet W Hammill, Maria A Cassera, Pippa H Newell, Paul D Hansen, and Ronald F Wolf

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Reply to "Analysis of 340 Patients with Solid Pseudopapillary Tumors of the Pancreas: A Closer Look at Patients with Metastatic Disease; Methodologic Issues," by Safiri, Saeid et al., Zeljka Jutric, Yelena Rozenfeld, Jan Grendar, and Ronald F Wolf

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Triple-negative breast cancer in the elderly: Prognosis and treatment., Henry G Kaplan, Judith A Malmgren, and Mary K Atwood

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Thin Melanoma with Nodal Involvement: Analysis of Demographic, Pathologic, and Treatment Factors with Regard to Prognosis., Giorgos Karakousis, Phyllis A Gimotty, Edmund K Bartlett, Myung-Shin Sim, Madalyn G Neuwirth, Douglas Fraker, Brian J Czerniecki, and Mark B Faries

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Astrocytes promote progression of breast cancer metastases to the brain via a KISS1-mediated autophagy., Natalya Kaverina, Anton V Borovjagin, Zaira Kadagidze, Anatoly Baryshnikov, Maria Baryshnikova, Dmitry Malin, Dhimankrishhna Ghosh, Nameeta Shah, Danny R Welch, Patrik Gabikian, Apollon Karseladze, Charles Cobbs, and Ilya V Ulasov

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Second Primary Malignant Neoplasms and Survival in Adolescent and Young Adult Cancer Survivors., Theresa H M Keegan, Archie Bleyer, Aaron S Rosenberg, Qian Li, and Melanie Goldfarb

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In Reply: Endoscopic and Gravity-Assisted Resection of Medial Temporo-occipital Lesions Through a Supracerebellar Transtentorial Approach: Technical Notes With Case Illustrations., Daniel F Kelly and Garni Barkhoudarian

Clinical Stage I vs Clinical Stage II Seminoma. Nuances and Assessing Treatment Guidelines, Mark J. Kelly

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Tumor-treating fields plus chemotherapy versus chemotherapy alone for glioblastoma at first recurrence: a post hoc analysis of the EF-14 trial., Santosh Kesari and Zvi Ram

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Brigatinib in Patients With Crizotinib-Refractory Anaplastic Lymphoma Kinase-Positive Non-Small-Cell Lung Cancer: A Randomized, Multicenter Phase II Trial., Dong-Wan Kim, Marcello Tiseo, Myung-Ju Ahn, Karen L Reckamp, Karin Holmskov Hansen, Sang-We Kim, Rudolf M Huber, Howard J. West, Harry J M Groen, Maximilian J Hochmair, Natasha B Leighl, Scott N Gettinger, Corey J Langer, Luis G Paz-Ares Rodríguez, Egbert F Smit, Edward S Kim, William Reichmann, Frank G Haluska, David Kerstein, and D Ross Camidge

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CCR4 is a determinant of melanoma brain metastasis., Anat Klein, Orit Sagi-Assif, Tsipi Meshel, Alona Telerman, Sivan Izraely, Shlomit Ben-Menachem, Jagadeesh Bayry, Diego M Marzese, Shuichi Ohe, Dave S B Hoon, Neta Erez, and Isaac P Witz

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A Comprehensive Patient-Derived Xenograft Collection Representing the Heterogeneity of Melanoma., Clemens Krepler, Katrin Sproesser, Patricia Brafford, Marilda Beqiri, Bradley Garman, Min Xiao, Batool Shannan, Andrea Watters, Michela Perego, Gao Zhang, Adina Vultur, Xiangfan Yin, Qin Liu, Ioannis N Anastopoulos, Bradley Wubbenhorst, Melissa A Wilson, Wei Xu, Giorgos Karakousis, Michael Feldman, Xiaowei Xu, Ravi Amaravadi, Tara C Gangadhar, David E Elder, Lauren E Haydu, Jennifer A Wargo, Michael A Davies, Yiling Lu, Gordon B Mills, Dennie T Frederick, Michal Barzily-Rokni, Keith T Flaherty, Dave S B Hoon, Michael Guarino, Joseph J Bennett, Randall W Ryan, Nicholas J Petrelli, Carol L Shields, Mizue Terai, Takami Sato, Andrew E Aplin, Alexander Roesch, David Darr, Steve Angus, Rakesh Kumar, Ensar Halilovic, Giordano Caponigro, Sebastien Jeay, Jens Wuerthner, Annette Walter, Matthias Ocker, Matthew B Boxer, Lynn Schuchter, Katherine L Nathanson, and Meenhard Herlyn

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Restriction Spectrum Imaging Improves Risk Stratification in Patients with Glioblastoma., A P Krishnan, R Karunamuni, K M Leyden, T M Seibert, R L Delfanti, J M Kuperman, H Bartsch, P Elbe, A Srikant, A M Dale, Santosh Kesari, D E Piccioni, J A Hattangadi-Gluth, N Farid, C R McDonald, and N S White

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Virtual Surgical Planning and Intraoperative Imaging in Management of Ballistic Facial and Mandibular Condylar Injuries., Philipp Kupfer, Allen Cheng, Ashish Patel, Melissa Amundson, Eric J Dierks, and R Bryan Bell

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Mutational Landscapes of Smoking-Related Cancers in Caucasians and African Americans: Precision Oncology Perspectives at Wake Forest Baptist Comprehensive Cancer Center., Ville Kytola, Umit Topaloglu, Lance D Miller, Rhonda L Bitting, Michael M Goodman, Ralph B D Agostino, Rodwige J Desnoyers, Carol Albright, George Yacoub, Shadi A Qasem, Barry DeYoung, Vesteinn Thorsson, Ilya Shmulevich, Meng Yang, Anastasia Shcherban, Matthew Pagni, Liang Liu, Matti Nykter, Kexin Chen, Gregory A Hawkins, Stefan C Grant, W Jeffrey Petty, Angela Tatiana Alistar, Edward A Levine, Edgar D Staren, Carl D Langefeld, Vincent Miller, Gaurav Singal, Robin M Petro, Mac Robinson, William Blackstock, Bayard L Powell, Lynne I Wagner, Kristie L Foley, Edward Abraham, Boris Pasche, and Wei Zhang

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Intensive care unit procedure utilization at the end of life among patients with cancer: a community hospital network experience The American Thoracic Society Washington DC, AS Laliberte, Candice L. Wilshire, and See all authors in comments

Mycobacterium bovis Bacillus Calmette-Guérin Alters Melanoma Microenvironment Favoring Antitumor T Cell Responses and Improving M2 Macrophage Function, Ricardo D Lardone, Alfred A Chan, Agnes F Lee, Leland J Foshag, Mark B Faries, Peter A Sieling, and Delphine J Lee

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Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade., Dung T Le, Jennifer N Durham, Kellie N Smith, Hao Wang, Bjarne R Bartlett, Laveet K Aulakh, Steve Lu, Holly Kemberling, Cara Wilt, Brandon S Luber, Fay Wong, Nilofer S Azad, Agnieszka A Rucki, Dan Laheru, Ross Donehower, Atif Zaheer, George A Fisher, Todd S Crocenzi, James J Lee, Tim F Greten, Austin G Duffy, Kristen K Ciombor, Aleksandra D Eyring, Bao H Lam, Andrew Joe, S Peter Kang, Matthias Holdhoff, Ludmila Danilova, Leslie Cope, Christian Meyer, Shibin Zhou, Richard M Goldberg, Deborah K Armstrong, Katherine M Bever, Amanda N Fader, Janis Taube, Franck Housseau, David Spetzler, Nianqing Xiao, Drew M Pardoll, Nickolas Papadopoulos, Kenneth W Kinzler, James R Eshleman, Bert Vogelstein, Robert A Anders, and Luis A Diaz

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The Importance of Standardization on Analyzing Circulating RNA., Inyoul Lee, David Baxter, Min Young Lee, Kelsey Scherler, and Kai Wang

Right internal jugular access as an alternative to femoral access for CardioMEMS implantation​, Rebecca Lewis, Lian Wang, Kateri Spinelli, Joshua Remick, Jeff Paulson, Jay Chappell, and Jacob Abraham

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Emerging Utility of Urinary Cell-free Nucleic Acid Biomarkers for Prostate, Bladder, and Renal Cancers., Selena Y Lin, Jennifer A Linehan, Timothy G Wilson, and Dave S B Hoon

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Modulation of Bax and mTOR for Cancer Therapeutics., Rui Li, Chunyong Ding, Jun Zhang, Maohua Xie, Dongkyoo Park, Ye Ding, Guo Chen, Guojing Zhang, Melissa Gilbert-Ross, Wei Zhou, Adam I Marcus, Shi-Yong Sun, Zhuo G Chen, Gabriel L Sica, Suresh S Ramalingam, Andrew T Magis, Haian Fu, Fadlo R Khuri, Walter J Curran, Taofeek K Owonikoko, Dong M Shin, Jia Zhou, and Xingming Deng

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Is tissue the issue?, Brian E Louie

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A Phase II Clinical Trial of an Aromatase Inhibitor for Postmenopausal Women with Lymphangioleiomyomatosis., Calvin Lu, Hye-Seung Lee, George P Pappas, Daniel F Dilling, Charles D Burger, Adrian Shifren, Srihari Veeraraghavan, Jeffrey T Chapman, Joseph Parambil, Stephen J Ruoss, Lisa R Young, Stephen R Hammes, Elizabeth J Kopras, Tammy Roads, Jeffrey P Krischer, and Francis X McCormack

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Mechanisms of radiotherapy-associated cognitive disability in patients with brain tumours., Milan T Makale, Carrie R McDonald, Jona A Hattangadi-Gluth, and Santosh Kesari

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The need for a network to establish and validate predictive biomarkers in cancer immunotherapy., Giuseppe V Masucci, Alessandra Cesano, Alexander Eggermont, Bernard A Fox, Ena Wang, Francesco M Marincola, Gennaro Ciliberto, Kevin Dobbin, Igor Puzanov, Janis Taube, Jennifer Wargo, Lisa H Butterfield, Lisa Villabona, Magdalena Thurin, Michael A Postow, Paul M Sondel, Sandra Demaria, Sanjiv Agarwala, and Paolo A Ascierto

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Community network lung cancer screening experience underrepresents medically underserved and geographically remote individuals, BM McCall, Candice L. Wilshire, CC Fuller, CR Gilbert, JT Fathi, JR Handy, KE Costas, BE Louie, RW Aye, AS Farivar, E Vallières, and JA Gorden

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Neuroinflammatory and cognitive consequences of combined radiation and immunotherapy in a novel preclinical model., Gwendolyn J McGinnis, David Friedman, Kristina H Young, Eileen Ruth S Torres, Charles R Thomas, Michael J Gough, and Jacob Raber

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Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes., James D McKay, Rayjean J Hung, Younghun Han, Xuchen Zong, Robert Carreras-Torres, David C Christiani, Neil E Caporaso, Mattias Johansson, Xiangjun Xiao, Yafang Li, Jinyoung Byun, Alison Dunning, Karen A Pooley, David C Qian, Xuemei Ji, Geoffrey Liu, Maria N Timofeeva, Stig E Bojesen, Xifeng Wu, Loic Le Marchand, Demetrios Albanes, Heike Bickeböller, Melinda C Aldrich, William S Bush, Adonina Tardon, Gad Rennert, M Dawn Teare, John K Field, Lambertus A Kiemeney, Philip Lazarus, Aage Haugen, Stephen Lam, Matthew B Schabath, Angeline S Andrew, Hongbing Shen, Yun-Chul Hong, Jian-Min Yuan, Pier Alberto Bertazzi, Angela C Pesatori, Yuanqing Ye, Nancy Diao, Li Su, Ruyang Zhang, Yonathan Brhane, Natasha Leighl, Jakob S Johansen, Anders Mellemgaard, Walid Saliba, Christopher A Haiman, Lynne R Wilkens, Ana Fernandez-Somoano, Guillermo Fernandez-Tardon, Henricus F M van der Heijden, Jin Hee Kim, Juncheng Dai, Zhibin Hu, Michael P A Davies, Michael W Marcus, Hans Brunnström, Jonas Manjer, Olle Melander, David C Muller, Kim Overvad, Antonia Trichopoulou, Rosario Tumino, Jennifer A Doherty, Matt P Barnett, Chu Chen, Gary E Goodman, Angela Cox, Fiona Taylor, Penella Woll, Irene Brüske, H-Erich Wichmann, Judith Manz, Thomas R Muley, Angela Risch, Albert Rosenberger, Kjell Grankvist, Mikael Johansson, Frances A Shepherd, Ming-Sound Tsao, Susanne M Arnold, Eric B Haura, Ciprian Bolca, Ivana Holcatova, Vladimir Janout, Milica Kontic, Jolanta Lissowska, Anush Mukeria, Simona Ognjanovic, Tadeusz M Orlowski, Ghislaine Scelo, Beata Swiatkowska, David Zaridze, Per Bakke, Vidar Skaug, Shanbeh Zienolddiny, Eric J Duell, Lesley M Butler, Woon-Puay Koh, Yu-Tang Gao, Richard S Houlston, John McLaughlin, Victoria L Stevens, Philippe Joubert, Maxime Lamontagne, David C Nickle, Ma'en Obeidat, Wim Timens, Bin Zhu, Lei Song, Linda Kachuri, María Soler Artigas, Martin D Tobin, Louise V Wain, Thorunn Rafnar, Thorgeir E Thorgeirsson, Gunnar W Reginsson, Kari Stefansson, Dana B Hancock, Laura J Bierut, Margaret R Spitz, Nathan C Gaddis, Sharon M Lutz, Fangyi Gu, Eric O Johnson, Ahsan Kamal, Claudio Pikielny, Dakai Zhu, Sara Lindströem, Xia Jiang, Rachel F Tyndale, Georgia Chenevix-Trench, Jonathan Beesley, Yohan Bossé, Stephen Chanock, Paul Brennan, Maria Teresa Landi, and Christopher I Amos

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Community network lung cancer screening experience underrepresents medically underserved and geographically remote individuals The International Association for the Study of Lung Ca, AM Meggyesy, Candice L. Wilshire, and See all authors in comments

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Timing of PD-1 Blockade Is Critical to Effective Combination Immunotherapy with Anti-OX40., David J Messenheimer, Shawn M. Jensen, Michael E Afentoulis, Keith W Wegman, Zipei Feng, David J Friedman, Michael J. Gough, Walter Urba, and Bernard A Fox

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Curcumin and Turmeric Modulate the Tumor-Promoting Effects of Iron In Vitro., Donald J Messner, Todd Robinson, and Kris V Kowdley

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Effect of Infla-Kine supplementation on the gene expression of inflammatory markers in peripheral mononuclear cells and on C-reactive protein in blood., Nina A Mikirova, Santosh Kesari, Thomas E Ichim, and Neil H Riordan

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Pack-Year Cigarette Smoking History for Determination of Lung Cancer Screening Eligibility. Comparison of the Electronic Medical Record versus a Shared Decision-making Conversation., Hannah E Modin, Joelle T Fathi, Christopher R Gilbert, Candice L. Wilshire, Andrew K Wilson, Ralph W Aye, Alexander S Farivar, Brian E Louie, Eric Vallières, and Jed A Gorden

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The Effect of Superparamagnetic Iron Oxide Nanoparticle Surface Charge on Antigen Cross-Presentation., Yongbin Mou, Yun Xing, Hongyan Ren, Zhihua Cui, Yu Zhang, Guangjie Yu, Walter J Urba, Qingang Hu, and Hongming Hu

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LINE-1 hypomethylation status of circulating cell-free DNA in plasma as a biomarker for colorectal cancer., Yuzo Nagai, Eiji Sunami, Yoko Yamamoto, Keisuke Hata, Satoshi Okada, Koji Murono, Koji Yasuda, Kensuke Otani, Takeshi Nishikawa, Toshiaki Tanaka, Tomomichi Kiyomatsu, Kazushige Kawai, Hiroaki Nozawa, Soichiro Ishihara, Dave S B Hoon, and Toshiaki Watanabe

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SMARCB1 is required for widespread BAF complex-mediated activation of enhancers and bivalent promoters., Robert T Nakayama, John L Pulice, Alfredo M Valencia, Matthew J McBride, Zachary M McKenzie, Mark A Gillespie, Wai Lim Ku, Mingxiang Teng, Kairong Cui, Robert T Williams, Seth H Cassel, He Qing, Christian J Widmer, George D Demetri, Rafael A Irizarry, Keji Zhao, Jeffrey A Ranish, and Cigall Kadoch

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Sex-specific associations of maternal birthweight with offspring birthweight in the Omega study., Collette N Ncube, Amelia R Gavin, Michelle A Williams, Chunfang Qiu, Tanya K Sorensen, and Daniel A Enquobahrie

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Impact of Time Between Diagnosis and SLNB on Outcomes in Cutaneous Melanoma., Daniel W Nelson, Stacey Stern, David E Elashoff, Robert Elashoff, John F Thompson, Nicola Mozzillo, Omgo E Nieweg, Harald J Hoekstra, Alistair J Cochran, and Mark B Faries

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Toxoplasma Modulates Signature Pathways of Human Epilepsy, Neurodegeneration & Cancer., Huân M Ngô, Ying Zhou, Hernan Lorenzi, Kai Wang, Taek-Kyun Kim, Yong Zhou, Kamal El Bissati, Ernest Mui, Laura Fraczek, Seesandra V Rajagopala, Craig W Roberts, Fiona L Henriquez, Alexandre Montpetit, Jenefer M Blackwell, Sarra E Jamieson, Kelsey Wheeler, Ian J Begeman, Carlos Naranjo-Galvis, Ney Alliey-Rodriguez, Roderick G Davis, Liliana Soroceanu, Charles Cobbs, Dennis A Steindler, Kenneth Boyer, A Gwendolyn Noble, Charles N Swisher, Peter T Heydemann, Peter Rabiah, Shawn Withers, Patricia Soteropoulos, Leroy Hood, and Rima McLeod

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The diagnostic challenge of low-grade ductal carcinoma in situ., Tracy Onega, Donald L Weaver, Paul D Frederick, Kimberly H Allison, Anna N A Tosteson, Patricia A Carney, Berta M Geller, Gary M Longton, Heidi D Nelson, Natalia V Oster, Margaret S Pepe, and Joann G Elmore

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RRx-001: a systemically non-toxic M2-to-M1 macrophage stimulating and prosensitizing agent in Phase II clinical trials., Bryan Oronsky, Ramasamy Paulmurugan, Kira Foygel, Jan Scicinski, Susan J Knox, Donna Peehl, Hongjuan Zhao, Shoucheng Ning, Pedro Cabrales, Thomas A Summers, Tony R Reid, William L Fitch, Michelle M Kim, Jane B Trepel, Min-Jung Lee, Santosh Kesari, Nacer D Abrouk, Regina M Day, Arnold Oronsky, Carolyn M Ray, and Corey A Carter

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The prognostic importance of scalp location in primary head and neck melanoma., Junko Ozao-Choy, Daniel W Nelson, Jason Hiles, Stacey L Stern, Jeong Lim Yoon, Myung Shin Sim, and Mark Faries

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Emergence of EGFR G724S mutation in EGFR-mutant lung adenocarcinoma post progression on osimertinib., A Oztan, S Fischer, A B Schrock, R L Erlich, C M Lovly, P J Stephens, J S Ross, V Miller, S M Ali, S-H I Ou, and L E Raez

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A Richter transformation PD-1 block party., John M Pagel

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Contemporary minimally invasive surgery for adrenal masses: it's not all about (pure) laparoscopy., Nicola Pavan, Ithaar Derweesh, Jens Rassweiler, Benjamin Challacombe, Homayoun Zargar, James Porter, Evangelos Liatsikos, Jihad Kaouk, Francesco Porpiglia, and Riccardo Autorino

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Robot assisted lymphadenectomy in urology: pelvic, retroperitoneal and inguinal., Giovannalberto Pini, Surena F Matin, Nazareno Suardi, Mihir Desai, Inderbir Gill, James Porter, Robert J Stein, Rene Sotelo, Franco Gaboardi, and Francesco Porpiglia

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Differentiated State of Initiating Tumor Cells Is Key to Distinctive Immune Responses Seen in H-Ras, Michael A Podolsky, Jacob T Bailey, Andrew J Gunderson, Carrie J Oakes, Kyle Breech, and Adam B Glick

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Ion channel expression patterns in glioblastoma stem cells with functional and therapeutic implications for malignancy., Julia Pollak, Karan G Rai, Cory C Funk, Sonali Arora, Eunjee Lee, Jun Zhu, Nathan D Price, Patrick J Paddison, Jan-Marino Ramirez, and Robert C Rostomily

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Multiscale mutation clustering algorithm identifies pan-cancer mutational clusters associated with pathway-level changes in gene expression., William Poole, Kalle Leinonen, Ilya Shmulevich, Theo A Knijnenburg, and Brady Bernard

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The Role of Lymphadenectomy for Renal Cell Carcinoma: Are we any Closer to an Answer?, James R Porter

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Lung Cancer and Family-Centered Patient Concerns, JR Rayburn, Candice L. Wilshire, Christopher R Gilbert, Brian Louie, Ralph W Aye, Alexander S Farivar, Eric Vallieres, and Jed A Gorden

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PS01.01 Treatment Planning in Non-Small Cell Lung Cancer shows Variable Utilization of Multidisciplinary Tumor Board Topic: Surgery, JR Rayburn, Candice L. Wilshire, Christopher R Gilbert, Brian Louie, Ralph W Aye, Alexander S Farivar, Eric Vallieres, and Jed A Gorden

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PS01. 02 Imaging Guideline-Recommendations Prior to Treatment for Non-Small Cell Lung Cancer Demonstrates Variable Compliance: Topic: Surgery, JR Rayburn, Candice L. Wilshire, Christopher R Gilbert, Brian Louie, Ralph W Aye, Alexander S Farivar, Eric Vallieres, and Jed A Gorden

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PS02. 04 Palliative care and hospice resources are underutilized in patients with advanced non-small cell lung cancer: topic: medical oncology, JR Rayburn, Candice L. Wilshire, Christopher R Gilbert, Brian Louie, Ralph W Aye, Alexander S Farivar, Eric Vallieres, and Jed A Gorden

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D22 THE COURSE OF CRITICAL ILLNESS: ADMISSION TO FOLLOW-UP: Underutilization Of End Of Life Care Plans And Palliative Care Resources In Lung Cancer Patients Admitted To Intensive Care Units, JR Rayburn, Candice L. Wilshire, Christopher R Gilbert, Roshanthi Weerasignhe, E Craig, and Jed A Gorden

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Imaging guideline-recommendations prior to treatment for non-small cell lung cancer demonstrates variable compliance International Association for the Study of Lung Cancer Multidisciplinary Symposium in Thoracic Oncology, JR Rayburn, Candice L. Wilshire, and See all authors in comments

Imaging guideline-recommendations prior to treatment for non-small cell lung cancer demonstrates variable compliance The International Association for the Study of Lung Cancer 18th World Conference on Lung Cancer Yokohama, JR Rayburn, Candice L. Wilshire, and See all authors in comments

Institutional assessment of adherence to guideline care in lung cancer diagnosis and staging negative impact of inconsistencies The American Thoracic Society Washington DC, JR Rayburn, Candice L. Wilshire, and See all authors in comments

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Palliative care and hospice resources are underutilized in patients with advanced non-small cell lung cancer International Association for the Study of Lung Cancer Multidisciplinary Symposium in Thoracic Oncology Chicago,, JR Rayburn, Candice L. Wilshire, and See all authors in comments

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Palliative care and hospice resources are underutilized in patients with advanced non-small cell lung cancer The International Association for the Study of Lung Cancer 18th World Conference on Lung Cancer Yokohama, Japan, JR Rayburn, Candice L. Wilshire, and See all authors in comments

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Treatment planning in non-small cell lung cancer shows variable utilization of multidisciplinary tumor board International Association for the Study of Lung Cancer Multidisciplinary Symposium in Thoracic Oncology Chicago,, JR Rayburn, Candice L. Wilshire, and See all authors in comments

Treatment planning in non-small cell lung cancer shows variable utilization of multidisciplinary tumor board The International Association for the Study of Lung Cancer 18th World Conference on Lung Cancer Yokohama, Japan, JR Rayburn, Candice L. Wilshire, and See all authors in comments

Underutilization of end of life care plans and palliative care resources in lung cancer patients admitted to intensive care units The American Thoracic Society Washington DC, JR Rayburn, Candice L. Wilshire, and See all authors in comments

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P3.13-029 Imaging Guideline-Recommendations Prior to Treatment for Non-Small Cell Lung Cancer Demonstrates Variable Compliance, J Rayburn, Candice L. Wilshire, Christopher R Gilbert, Brian Louie, Ralph W Aye, Alexander S Farivar, Eric Vallieres, and Jed A Gorden

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Anomalies in the dominant sarcoidosis paradigm justify its displacement., Jerome M Reich

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In Memoriam: Laurence E. Karp (1939-2016)., Robert Resta

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The ISB Cancer Genomics Cloud: A Flexible Cloud-Based Platform for Cancer Genomics Research., Sheila M Reynolds, Michael Miller, Phyliss Lee, Kalle Leinonen, Suzanne M Paquette, Zack Rodebaugh, Abigail Hahn, David L Gibbs, Joseph Slagel, William J Longabaugh, Varsha Dhankani, Madelyn Reyes, Todd Pihl, Mark Backus, Matthew Bookman, Nicole Deflaux, Jonathan Bingham, David Pot, and Ilya Shmulevich

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Tumor and Microenvironment Evolution during Immunotherapy with Nivolumab., Nadeem Riaz, Jonathan J Havel, Vladimir Makarov, Alexis Desrichard, Walter Urba, Jennifer S Sims, F Stephen Hodi, Salvador Martín-Algarra, Rajarsi Mandal, William H Sharfman, Shailender Bhatia, Wen-Jen Hwu, Thomas F Gajewski, Craig L Slingluff, Diego Chowell, Sviatoslav M Kendall, Han Chang, Rachna Shah, Fengshen Kuo, Luc G T Morris, John-William Sidhom, Jonathan P Schneck, Christine E Horak, Nils Weinhold, and Timothy A Chan