The Cancer Institute is a leader in cutting-edge treatments. Using a truly multidisciplinary approach, patients have access to advanced diagnostics, minimally invasive surgical interventions, and personalized genomic and immune-oncologic treatment options. Our team of cancer specialists – many of whom completed fellowships and specialty training at prestigious academic centers – offers comprehensive services for individuals with a cancer diagnosis.

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Submissions from 2018

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New Clues to Human Longevity, Brian D. Piening

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Impact of Specimen Heterogeneity on Biomarkers in Repository Samples from Patients with Acute Myeloid Leukemia: A SWOG Report., Era L Pogosova-Agadjanyan, Anna Moseley, Megan Othus, Frederick R Appelbaum, Thomas R Chauncey, I-Ming L Chen, Harry P Erba, John E Godwin, Min Fang, Kenneth J Kopecky, Alan F List, Galina L Pogosov, Jerald P Radich, Cheryl L Willman, Brent L Wood, Soheil Meshinchi, and Derek L Stirewalt

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Late stage tumor regression after PD-L1 blockade with a concurrent OX40 agonist., Fanny Polesso, Andrew D Weinberg, and Amy E Moran

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Percutaneous coronary intervention in cancer patients: a report of the prevalence and outcomes in the United States., Jessica E Potts, Cezar A Iliescu, Juan C Lopez Mattei, Sara C Martinez, Lene Holmvang, Peter Ludman, Mark A De Belder, Chun Shing Kwok, Muhammad Rashid, David L Fischman, and Mamas A Mamas

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An anatomic transcriptional atlas of human glioblastoma., Ralph B Puchalski, Nameeta Shah, Jeremy Miller, Rachel Dalley, Steve R Nomura, Jae-Guen Yoon, Kimberly A Smith, Michael Lankerovich, Darren Bertagnolli, Kris Bickley, Andrew F Boe, Krissy Brouner, Stephanie Butler, Shiella Caldejon, Mike Chapin, Suvro Datta, Nick Dee, Tsega Desta, Tim Dolbeare, Nadezhda Dotson, Amanda Ebbert, David Feng, Xu Feng, Michael Fisher, Garrett Gee, Jeff Goldy, Lindsey Gourley, Benjamin W Gregor, Guangyu Gu, Nika Hejazinia, John Hohmann, Parvinder Hothi, Robert Howard, Kevin Joines, Ali Kriedberg, Leonard Kuan, Chris Lau, Felix Lee, Hwahyung Lee, Tracy Lemon, Fuhui Long, Naveed Mastan, Erika Mott, Chantal Murthy, Kiet Ngo, Eric Olson, Melissa Reding, Zack Riley, David Rosen, David Sandman, Nadiya Shapovalova, Clifford R Slaughterbeck, Andrew Sodt, Graham Stockdale, Aaron Szafer, Wayne Wakeman, Paul E Wohnoutka, Steven J White, Don Marsh, Robert C Rostomily, Lydia Ng, Chinh Dang, Allan Jones, Bart Keogh, Haley R Gittleman, Jill S Barnholtz-Sloan, Patrick J Cimino, Megha S Uppin, C Dirk Keene, Farrokh R Farrokhi, Justin D Lathia, Michael E Berens, Antonio Iavarone, Amy Bernard, Ed Lein, John W Phillips, Steven W Rostad, Charles Cobbs, Michael J Hawrylycz, and Greg D Foltz

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Tumor infiltrating lymphocyte recruitment after peri-lymphatic IRX-2 cytokine immunotherapy in resectable breast cancer and head and neck carcinoma, Joanna Pucilowska, Venkatesh Rajamanickam, Nikki Moxon, Monil Shah, Maritza Martel, Alison Conlin, James E. Egan, and David B. Page

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Perilymphatic IRX-2 cytokine therapy to enhance tumor infiltrating lymphocytes and PD-L1 expression preceding curative-intent therapy in early stage breast cancer, Joanna Pucilowska, Venkatesh Rajamanickam, Katherine Sanchez, Valerie Conrad, Alison Conlin, Shagheyegh Aliabadi-Wahle, Shu-Ching Chang, Gary Grunkemeier, Nikki Moxon, Staci Mellinger, Maritza Martel, James Egan, Monil Shah, and David B Page

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The Integrated Genomic Landscape of Thymic Epithelial Tumors., Milan Radovich, Curtis R Pickering, Ina Felau, Gavin Ha, Hailei Zhang, Heejoon Jo, Katherine A Hoadley, Pavana Anur, Jiexin Zhang, Mike McLellan, Reanne Bowlby, Thomas Matthew, Ludmila Danilova, Apurva M Hegde, Jaegil Kim, Mark D M Leiserson, Geetika Sethi, Charles Lu, Michael Ryan, Xiaoping Su, Andrew D Cherniack, Gordon Robertson, Rehan Akbani, Paul Spellman, John N Weinstein, D Neil Hayes, Ben Raphael, Tara Lichtenberg, Kristen Leraas, Jean Claude Zenklusen, Junya Fujimoto, Cristovam Scapulatempo-Neto, Andre L Moreira, David Hwang, James Huang, Mirella Marino, Robert Korst, Giuseppe Giaccone, Yesim Gokmen-Polar, Sunil Badve, Arun Rajan, Philipp Ströbel, Nicolas Girard, Ming S Tsao, Alexander Marx, Anne S Tsao, and Patrick J Loehrer

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Reviewing the Risk of Colorectal Cancer in Inflammatory Bowel Disease After Liver Trasnplantation for Primary Sclerosing Cholangitis., Bhavana Bhagya Rao, Bret Lashner, and Kris V Kowdley

Referrals for palliative care and hospice are underutilized in patients with advanced non-small cell lung cancer, JR Rayburn, CL Wilshire, CR Gilbert, BE Louie, RW Aye, AS Farivar, E Vallières, and JA Gorden

Multistate healthcare network underutilizes valuable end-of-life resources in stage IV non-small cell lung cancer, JR Rayburn, CL Wilshire, CR Gilbert, RK Weerasinghe, BE Louie, RW Aye, AS Farivar, E Vallières, and JA Gorden

Patterns of multidisciplinary tumor board utilization in the management of non-small cell lung cancer The American Thoracic Society San Diego, California, JR Rayburn, CL Wilshire, and See all authors in comments

Reducing the use of catheters, tubes and imaging after hiatal hernia surgery significantly reduces length of hospital stay Society of American Gastrointestinal and Endoscopic Surgeons Annual Meeting Seattle, Washington, JR Rayburn, CL Wilshire, and See all authors in comments

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Chirping Rales in Hypersensitivity Pneumonitis., Jerome M Reich

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Reservations Regarding Lung Cancer Screening Guidelines., Jerome M Reich

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Sarcoidosis in WTC-Exposed workers., Jerome M Reich

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The Curious Omission of Treatment as a Predictor of Pulmonary Sarcoidosis Mortality., Jerome M Reich

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Erratum to inequivalence of non-aggressiveness in clinically diagnosed lung cancers and overdiagnosis in lung cancer screening trials., Jerome M Reich and Jong S Kim

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Pazopanib with low fat meal (PALM) in advanced renal cell carcinoma., Melissa A Reimers, Maryann M Shango, Stephanie Daignault-Newton, Rachel Dedinsky, Danielle Karsies, Shawna Kraft, Liam Riddle, Jeremy A Felton, Bo Wen, Christina Gersch, James M Rae, Bruce G Redman, and Ajjai S Alva

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What have we been trying to do and have we been any good at it? A history of measuring the success of genetic counseling., Robert G Resta

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Limitations in learning: How treatment verifications fail and what to do about it?, Susan Richardson and Bruce Thomadsen

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Adverse Events, Patterns of Tumor Lysis Syndrome Prophylaxis and Management, and Dosing Patterns in a Large Cohort of Venetoclax Treated CLL Patients in Community and Academic Settings, Lindsey E. Roeker, Neil Bailey, and See full list of authors in comments

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NKTR-214 (CD122-biased agonist) and NKTR-262 (TLR7/8 agonist) combination treatment pairs local innate immune activation with systemic CD8+ T cell expansion to enhance anti-tumor immunity, Annah S. Rolig, Daniel Rose, Saul Kivimäe, Deborah Charych, Werner Rubas, Jonathan Zalevsky, and William L. Redmond

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Genetic modifiers of radon-induced lung cancer risk: a genome-wide interaction study in former uranium miners., Albert Rosenberger, Rayjean J Hung, David C Christiani, Neil E Caporaso, Geoffrey Liu, Stig E Bojesen, Loic Le Marchand, Ch A Haiman, Demetrios Albanes, Melinda C Aldrich, Adonina Tardon, G Fernández-Tardón, Gad Rennert, John K Field, B Kiemeney, Philip Lazarus, Aage Haugen, Shanbeh Zienolddiny, Stephen Lam, Matthew B Schabath, Angeline S Andrew, Hans Brunnsstöm, Gary E Goodman, Jennifer A Doherty, Chu Chen, M Dawn Teare, H-Erich Wichmann, Judith Manz, Angela Risch, Thomas R Muley, Mikael Johansson, Paul Brennan, Maria Teresa Landi, Christopher I Amos, Beate Pesch, Georg Johnen, Thomas Brüning, Heike Bickeböller, and Maria Gomolka

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Comparison of Quality Oncology Practice Initiative Metrics in Solid Tumor Oncology Clinic With or Without Concomitant Supportive Oncology Consultation., Rachel Rosenblum, Ran Huo, Bethann Scarborough, Nathan Goldstein, and Cardinale B Smith

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MHC class I loaded ligands from breast cancer cell lines: A potential HLA-I-typed antigen collection., Dmitri V Rozanov, Nikita D Rozanov, Kami E Chiotti, Ashok Reddy, Phillip A Wilmarth, Larry L David, Seung W Cha, Sunghee Woo, Pavel Pevzner, Vineet Bafna, Gregory G Burrows, Juha K Rantala, Trevor Levin, Pavana Anur, Katie Johnson-Camacho, Shaadi Tabatabaei, Daniel J Munson, Tullia C Bruno, Jill E Slansky, John W Kappler, Naoto Hirano, Sebastian Boegel, Bernard A Fox, Colt Egelston, Diana L Simons, Grecia Jimenez, Peter P Lee, Joe W Gray, and Paul T Spellman

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Brain metastasis DNA methylomes, a novel resource for the identification of biological and clinical features., Matthew P Salomon, Javier I J Orozco, James S Wilmott, Parvinder Hothi, Ayla O Manughian-Peter, C Cobbs, Richard A Scolyer, Dave S B Hoon, and Diego M Marzese

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The Epigenomic Landscape of Pituitary Adenomas Reveals Specific Alterations and Differentiates Among Acromegaly, Cushing's Disease and Endocrine-Inactive Subtypes., Matthew P Salomon, Xiaowen Wang, Diego M Marzese, Sandy C Hsu, Nellie Nelson, Xin Zhang, Chikako Matsuba, Yuki Takasumi, Carmen Ballesteros-Merino, Bernard A Fox, Garni Barkhoudarian, Daniel F Kelly, and Dave S B Hoon

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Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images., Joel Saltz, Rajarsi Gupta, Le Hou, Tahsin Kurc, Pankaj Singh, Vu Nguyen, Dimitris Samaras, Kenneth R Shroyer, Tianhao Zhao, Rebecca Batiste, John Van Arnam, Ilya Shmulevich, Arvind U K Rao, Alexander J Lazar, Ashish Sharma, and Vésteinn Thorsson

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Preliminary results from a first-in-human phase 1 study of the CD40 agonist monoclonal antibody (mAb) CDX-1140, Rachel Sanborn, Michael S. Gordon, Mark O'Hara, Nina Bhardwaj, Yi He, Tracey Rawls, Tibor Keler, and Michael Yellin

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Oncogenic Signaling Pathways in The Cancer Genome Atlas., Francisco Sanchez-Vega, Marco Mina, Joshua Armenia, Walid K Chatila, Augustin Luna, Konnor C La, Sofia Dimitriadoy, David L Liu, Havish S Kantheti, Sadegh Saghafinia, Debyani Chakravarty, Foysal Daian, Qingsong Gao, Matthew H Bailey, Wen-Wei Liang, Steven M Foltz, Ilya Shmulevich, Li Ding, Zachary Heins, Angelica Ochoa, Benjamin Gross, Jianjiong Gao, Hongxin Zhang, Ritika Kundra, Cyriac Kandoth, Istemi Bahceci, Leonard Dervishi, Ugur Dogrusoz, Wanding Zhou, Hui Shen, Peter W Laird, Gregory P Way, Casey S Greene, Han Liang, Yonghong Xiao, Chen Wang, Antonio Iavarone, Alice H Berger, Trever G Bivona, Alexander J Lazar, Gary D Hammer, Thomas Giordano, Lawrence N Kwong, Grant McArthur, Chenfei Huang, Aaron D Tward, Mitchell J Frederick, Frank McCormick, Matthew Meyerson, Eliezer M Van Allen, Andrew D Cherniack, Giovanni Ciriello, Chris Sander, and Nikolaus Schultz

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Vitamin D3 decreases glycolysis and invasiveness, and increases cellular stiffness in breast cancer cells, Julianna Maria Santos, Zeina Shereen Khan, Maliha Tabassum Munir, Kaiser Tarafdar, Shaikh Mizanoor Rahman, and Fazle Hussain

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Poor outcome with hematopoietic stem cell transplantation for bone marrow failure and MDS with severe MIRAGE syndrome phenotype., Jay Sarthy, Ji Zha, Daria Babushok, Archana Shenoy, Jian-Meng Fan, Gerald Wertheim, Adam Himebauch, Ashley Munchel, Agne Taraseviciute, Samuel Yang, Hirohito Shima, Satoshi Narumi, Soheil Meshinchi, and Timothy S Olson

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Evolution of the mutational process under relaxed selection in Caenorhabditis elegans., Ayush Shekhar Saxena, Matthew P Salomon, Chikako Matsuba, Shu-Dan Yeh, and Charles F Baer

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Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas., Franz X Schaub, Varsha Dhankani, Ashton C Berger, Mihir Trivedi, Anne B Richardson, Reid Shaw, Wei Zhao, Xiaoyang Zhang, Andrea Ventura, Yuexin Liu, Donald E Ayer, Peter J Hurlin, Andrew D Cherniack, Robert N Eisenman, Brady Bernard, Carla Grandori, and Bernard Brady

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Telomerase reverse transcriptase promoter alterations across cancer types as detected by next-generation sequencing: A clinical and molecular analysis of 423 patients., Maria Schwaederle, Nithya Krishnamurthy, Gregory A Daniels, David E Piccioni, Santosh Kesari, Paul T Fanta, Richard B Schwab, Sandip P Patel, Barbara A Parker, and Razelle Kurzrock

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Impact of tumour histology on survival in advanced cervical carcinoma: an NRG Oncology/Gynaecologic Oncology Group Study., Leigh G Seamon, James J Java, Bradley J Monk, Richard T Penson, Jubilee Brown, Robert S Mannel, Anna Oaknin, Mario M Leitao, Eric L Eisenhauer, Harry J Long, Shu Y Liao, and Krishnansu S Tewari

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Editorial: frequency of surveillance and survival in hepatocellular carcinoma., N H Senussi and K V Kowdley

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The Ecstacy of Gold: Patent Expirations for Trastuzumab, Bevacizumab, Rituximab, and Cetuximab., Tasha R Serna-Gallegos, Christopher J La-Fargue, and Krishnansu S Tewari

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The Ecstacy of Gold: Patent Expirations for Trastuzumab, Bevacizumab, Rituximab, and Cetuximab, Tasha R. Serna-Gallegos, Christopher J. La-Fargue, and Krishnansu S Tewari

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Centromere protein F (CENPF), a microtubule binding protein, modulates cancer metabolism by regulating pyruvate kinase M2 phosphorylation signaling., Muhammad Shahid, Minyoung Lee, Honit Piplani, Allen M Andres, Bo Zhou, Austin Yeon, Minjung Kim, Hyung L Kim, and Jayoung Kim

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Large pseudoencapsulated subcutaneous angiomyxoma: Surgical management., Christine M Shaver, Steven E Kolker, and Richard G Bennett

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Integrated Molecular Characterization of Testicular Germ Cell Tumors., Hui Shen, Juliann Shih, Daniel P Hollern, Linghua Wang, Reanne Bowlby, Satish K Tickoo, Vésteinn Thorsson, Andrew J Mungall, Yulia Newton, Apurva M Hegde, Joshua Armenia, Francisco Sánchez-Vega, John Pluta, Louise C Pyle, Rohit Mehra, Victor E Reuter, Guilherme Godoy, Jeffrey Jones, Carl S Shelley, Darren R Feldman, Daniel O Vidal, Davor Lessel, Tomislav Kulis, Flavio M Cárcano, Kristen M Leraas, Tara M Lichtenberg, Denise Brooks, Andrew D Cherniack, Juok Cho, David I Heiman, Katayoon Kasaian, Minwei Liu, Michael S Noble, Liu Xi, Hailei Zhang, Wanding Zhou, Jean C ZenKlusen, Carolyn M Hutter, Ina Felau, Jiashan Zhang, Nikolaus Schultz, Gad Getz, Matthew Meyerson, Joshua M Stuart, Rehan Akbani, David A Wheeler, Peter W Laird, Katherine L Nathanson, Victoria K Cortessis, and Katherine A Hoadley

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Immunotherapy in metastatic urothelial carcinoma: focus on immune checkpoint inhibition., Arlene Siefker-Radtke and Brendan Curti

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Intraoperative Radiation Therapy (IORT): A Series of 1000 Tumors., Melvin J Silverstein, Melinda Epstein, Brian Kim, Kevin Lin, Sadia Khan, Lincoln Snyder, Lisa Guerra, Colleen Coleman, and Peter Chen

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Gastric hibernoma: a novel location and presentation of a rare tumor., Shane P Smith, Andrew F Feczko, Matias Mihura, Jey-Hsin Chen, and Alexander S Farivar

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Glioblastoma radiomics: can genomic and molecular characteristics correlate with imaging response patterns?, Michael H Soike, Emory R McTyre, Nameeta Shah, Ralph B Puchalski, Jordan A Holmes, Anna K Paulsson, Lance D Miller, Christina K Cramer, Glenn J Lesser, Roy E Strowd, William H Hinson, Ryan T Mott, Annette J Johnson, Hui-Wen Lo, Adrian W Laxton, Stephen B Tatter, Waldemar Debinski, and Michael D Chan

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Multimodality Therapy for N2 Non-Small Cell Lung Cancer: An Evolving Paradigm., Jonathan D Spicer, Jitesh B Shewale, David B Nelson, Kyle G Mitchell, Matthew J Bott, Eric Vallieres, Candice Wilshire, Ara A Vaporciyan, Stephen G Swisher, David R Jones, Gail E Darling, and Boris Sepesi

Performance status and resource utilization in patients receiving palliative with stage IV advanced non-small cell lung cancer The International Association for the Study of Lung Cancer 19th World Conferenc, KM Spiegel, CL Wilshire, and See all authors in comments

Pulmonary nodule resection characteristics: experience from lung cancer screening programs in a multi-state, community-based health care network The American Thoracic Society San Diego, California, KM Spiegel, CL Wilshire, and See all authors in comments

Referrals for Lung Cancer Screening: frontline health care professional participation remains low in the community The American Thoracic Society San Diego, California, KM Spiegel, CL Wilshire, and See all authors in comments

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Disparities in fertility-sparing surgery in adolescent and young women with stage I ovarian dysgerminoma., Laura L Stafman, Ilan I Maizlin, Matthew Dellinger, Kenneth W Gow, Melanie Goldfarb, Jed G Nuchtern, Monica Langer, Sanjeev A Vasudevan, John J Doski, Adam B Goldin, Mehul Raval, and Elizabeth A Beierle

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Combined anti-PD-1 and anti-LAG-3 checkpoint blockade enhances CD8+ TIL effector function while reducing Tregs leading to reduced immune suppression and improved overall survival, Elizabeth Sturgill, Courtney Mick, David Jenkins, Johanna Kaufmann, and William L. Redmond

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An update on the Society for Immunotherapy of Cancer consensus statement on tumor immunotherapy for the treatment of cutaneous melanoma: version 2.0., Ryan J Sullivan, Michael B Atkins, John M Kirkwood, Sanjiv S Agarwala, Joseph I Clark, Marc S Ernstoff, Leslie Fecher, Thomas F Gajewski, Brian Gastman, David H Lawson, Jose Lutzky, David F McDermott, Kim A Margolin, Janice M Mehnert, Anna C Pavlick, Jon M Richards, Krista M Rubin, William Sharfman, Steven Silverstein, Craig L Slingluff, Vernon K Sondak, Ahmad A Tarhini, John A Thompson, Walter J Urba, Richard L White, Eric D Whitman, F Stephen Hodi, and Howard L Kaufman

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Association of Immunologic Markers With Survival in Upfront Resectable Pancreatic Cancer., Ephraim S Tang, Philippa H Newell, Ronald F Wolf, Paul Daniel Hansen, Benjamin Cottam, Carmen Ballesteros-Merino, and Michael J Gough

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Clinical outcomes five years after POEM for treatment of primary esophageal motility disorders., Ezra N Teitelbaum, Christy M Dunst, Kevin M Reavis, Ahmed M Sharata, Marc A Ward, Steven R DeMeester, and Lee L Swanström

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Ovarian Cancer, Krishnansu S Tewari, Richard T. Penson, and Bradley J. Monk

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Randomized phase II trial of bevacizumab plus everolimus versus bevacizumab alone for recurrent or persistent ovarian, fallopian tube or peritoneal carcinoma: An NRG oncology/gynecologic oncology group study., William P Tew, Michael W Sill, Joan L Walker, Angeles Alvarez Secord, Albert J Bonebrake, Jeanne M Schilder, Ashley Stuckey, Laurel Rice, Krishnansu S Tewari, and Carol A Aghajanian

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Tumor mutational burden is a determinant of immune-mediated survival in breast cancer., Alexandra Thomas, Eric D Routh, Ashok Pullikuth, Guangxu Jin, Jing Su, Jeff W Chou, Katherine A Hoadley, Cristin Print, Nick Knowlton, Michael A Black, Sandra Demaria, Ena Wang, Davide Bedognetti, Wendell D Jones, Gaurav A Mehta, Michael L Gatza, Charles M Perou, David B Page, Pierre Triozzi, and Lance D Miller

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Variability in invasive mediastinal staging for lung cancer: A multicenter regional study., Lucas W Thornblade, Douglas E Wood, Michael S Mulligan, Alexander S Farivar, Michal Hubka, Kimberly E Costas, Bahirathan Krishnadasan, and Farhood Farjah

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The Immune Landscape of Cancer., Vésteinn Thorsson, David L Gibbs, Scott D Brown, Denise Wolf, Dante S Bortone, Tai-Hsien Ou Yang, Eduard Porta-Pardo, Galen F Gao, Christopher L Plaisier, James A Eddy, Elad Ziv, Aedin C Culhane, Evan O Paull, I K Ashok Sivakumar, Andrew J Gentles, Raunaq Malhotra, Farshad Farshidfar, Antonio Colaprico, Joel S Parker, Lisle E Mose, Nam Sy Vo, Jianfang Liu, Yuexin Liu, Janet Rader, Varsha Dhankani, Sheila M Reynolds, Reanne Bowlby, Andrea Califano, Andrew D Cherniack, Dimitris Anastassiou, Davide Bedognetti, Arvind Rao, Ken Chen, Alexander Krasnitz, Hai Hu, Tathiane M Malta, Houtan Noushmehr, Chandra Sekhar Pedamallu, Susan Bullman, Akinyemi I Ojesina, Andrew Lamb, Wanding Zhou, Hui Shen, Toni K Choueiri, John N Weinstein, Justin Guinney, Joel Saltz, Robert A Holt, Charles E Rabkin, Alexander J Lazar, Jonathan S Serody, Elizabeth G Demicco, Mary L Disis, Benjamin G Vincent, and Llya Shmulevich

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Mertk is a therapeutic target in combination with radiation to promote adaptive immune tumor responses, Garth Tormoen, Jason R Baird, Gwen Kramer, Shelly Bambina, Marka R Crittenden, and Michael J. Gough

Role of the immunosuppressive microenvironment in immunotherapy., Garth W Tormoen, Marka R Crittenden, and Michael J. Gough

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Galectin - Method for Enhancing Specific Immunotherapies in Cancer Treatment, Peter G. Traber, William L. Redmond, Eliezer Zomer, Anatole Klyosov, and Stephanie N. Linch

Somatic Mutations and Immunotherapy, Eric Tran

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Su1776 - Superior Survival of South and East Asians with Colorectal Carcinoma in the United States, Abhineet Uppal, Ramkishen Narayanan, Shu-Ching Chang, Trevan Fischer, and Melanie Goldfarb

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Can high-volume teams of anesthesiologists and surgeons decrease perioperative costs for pancreatic surgery?, Abhineet Uppal, Brooke Vuong, Ahmed Dehal, Stacey L Stern, Juan Mejia, Roshanthi Weerasinghe, Vandana Kapoor, Evan Ong, Paul D Hansen, and Anton J Bilchik

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Adjuvant chemotherapy for resected earlier stage adenocarcinomas with unfavorable architecture. Should we incorporate histologic findings to the decision tree?, Eric Vallières

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Glatiramer Acetate Enhances Myeloid-Derived Suppressor Cell Function via Recognition of Paired Ig-like Receptor B., William van der Touw, Kyeongah Kang, Yi Luan, Ge Ma, Sunny Mai, Lihui Qin, Guanglin Bian, Ruihua Zhang, Sathish Kumar Mungamuri, Hong-Ming Hu, Cheng Cheng Zhang, Stuart A Aaronson, Marc Feldmann, Wen-Chin Yang, Shu-Hsia Chen, and Ping-Ying Pan

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Autophagosome-based strategy to monitor apparent tumor-specific CD8 T cells in patients with prostate cancer., Rieneke van de Ven, Traci L Hilton, Hong-Ming Hu, Christopher J Dubay, Daniel Haley, Christopher Paustian, Sachin Puri, Walter Urba, Brendan Curti, Sandra Aung, and Bernard A Fox

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Autophagosome-based strategy to monitor apparent tumor-specific CD8 T cells in patients with prostate cancer, Rieneke van de Ven, Traci L. Hilton, Hong-Ming Hu, Christopher J. Dubay, Daniel Haley, Christopher Paustian, Sachin Puri, Walter J. Urba, Brendan D. Curti, Sandra Aung, and Bernard A. Fox

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Variations in cancer care for adolescents and young adults (AYAs) with ductal carcinoma in situ., Amy Voci, Bradley Bandera, Emily Ho, Jihey Lee, Melanie Goldfarb, and Maggie DiNome

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Impact of port site scar on perception of patients with breast cancer: patient-reported outcomes., Amy Voci, David Lee, Emily Ho, Rebecca Crane-Okada, and Maggie DiNome

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Trastuzumab Emtansine for Residual Invasive HER2-Positive Breast Cancer., Gunter von Minckwitz, Chiun-Sheng Huang, Max S Mano, Sibylle Loibl, Eleftherios P Mamounas, Michael Untch, Norman Wolmark, Priya Rastogi, Andreas Schneeweiss, Andres Redondo, Hans H Fischer, William Jacot, Alison Conlin, Claudia Arce-Salinas, Irene L Wapnir, Christian Jackisch, Michael P DiGiovanna, Peter A Fasching, John P Crown, Pia Wülfing, Zhimin Shao, Elena Rota Caremoli, Haiyan Wu, Lisa H Lam, David Tesarowski, Melanie Smitt, Hannah Douthwaite, Stina M Singel, and Charles E Geyer

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What Are the Most Significant Cost and Value Drivers for Pancreatic Resection in an Integrated Healthcare System?, Brooke Vuong, Ahmed N Dehal, Abhineet Uppal, Stacey L Stern, Juan Mejia, Roshanthi Weerasinghe, Vandana Kapoor, Evan Ong, Paul D Hansen, and Anton J Bilchik

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Isolation of Breast cancer CTCs with multitargeted buoyant immunomicrobubbles., Guankui Wang, Halli Benasutti, Jessica F Jones, Guixin Shi, Michael Benchimol, Sandeep Pingle, Santosh Kesari, Yasan Yeh, Li-En Hsieh, Yu-Tsueng Liu, Anthony Elias, and Dmitri Simberg

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KDM6B counteracts EZH2-mediated suppression of IGFBP5 to confer resistance to PI3K/AKT inhibitor treatment in breast cancer., Wenyu Wang, Keng Gat Lim, Min Feng, Yi Bao, Puay Leng Lee, Cai Yu, Yufeng Chen, Hao Zhang, Diego M Marzese, Dave S B Hoon, and Qiang Yu

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Impact on Oncology Practices of Including Drug Costs in Bundled Payments., Jeffery C Ward, Laura A Levit, Ray D Page, John E Hennessy, John V Cox, Deborah Y Kamin, Suanna S Bruinooge, Ya-Chen Tina Shih, and Blase N Polite

Factors predicting attrition in community-based healthcare network lung cancer screening programs The International Association for the Study of Lung Cancer 19th World Conference on Lung Canc, RK Weerasinghe, CL Wilshire, and See all authors in comments

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Tumor cell-released autophagosomes (TRAPs) promote immunosuppression through induction of M2-like macrophages with increased expression of PD-L1., Zhi-Fa Wen, Hongxiang Liu, Rong Gao, Meng Zhou, Jie Ma, Yue Zhang, Jinjin Zhao, Yongqiang Chen, Tianyu Zhang, Fang Huang, Ning Pan, Jinping Zhang, Bernard A Fox, Hong-Ming Hu, and Li-Xin Wang

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Moving Beyond Limited and Extensive Staging of Small Cell Lung Cancer., Howard Jack West

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Redefining the Value Proposition of Precision Oncology: Can We Integrate Genomic Testing Without Overselling It?, Howard Jack West

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Paired Phase II Studies of Erlotinib/Bevacizumab for Advanced Bronchioloalveolar Carcinoma or Never Smokers With Advanced Non-Small-cell Lung Cancer: SWOG S0635 and S0636 Trials., Howard L West, James Moon, Antoinette J Wozniak, Philip Mack, Fred R Hirsch, Martin J Bury, Myron Kwong, Dorothy D Nguyen, Dennis F Moore, Jieling Miao, Mary Redman, Karen Kelly, and David R Gandara

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Tunneled pleural catheter use for pleural palliation does not increase infection rate in patients with treatment-related immunosuppression., Candice L Wilshire, Christopher R Gilbert, Brian E Louie, Ralph W Aye, Alexander S Farivar, Eric Vallières, and Jed A Gorden

Multicenter review suggests tunnelled pleural catheter use in antineoplastic therapy-related immun, CL Wilshire

Multicenter review of thymectomy indicated for myasthenia gravis favors a left-sided approach and lower severity class, CL Wilshire, CC Fuller, AF Ghanim, RJ Cerfolio, MW Onaitis, V Joshi, DA Wigle, RW Aye, AS Farivar, E Vallières, and BE Louie

Multicenter review of tunnelled pleural catheter implementation and use in patients with malignant pleural effusions, CL Wilshire, CR Gilbert, JA Akulian, R Asciak, B Bevill, KR Davidson, A Delgado, HJ Lee, JE Lewis, F Maldonado, NJ Pastis, NM Rahman, CB Reddy, and See additional authors in comments

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Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: American Society of Clinical Oncology/College of American Pathologists Clinical Practice Guideline Focused Update., Antonio C Wolff, M Elizabeth Hale Hammond, Kimberly H Allison, Brittany E Harvey, Pamela B Mangu, John M S Bartlett, Michael Bilous, Ian O Ellis, Patrick Fitzgibbons, Wedad Hanna, Robert B Jenkins, Michael F Press, Patricia A Spears, Gail H Vance, Giuseppe Viale, Lisa M McShane, and Mitchell Dowsett

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Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: American Society of Clinical Oncology/College of American Pathologists Clinical Practice Guideline Focused Update., Antonio C Wolff, M Elizabeth Hale Hammond, Kimberly H Allison, Brittany E Harvey, Pamela B Mangu, John M S Bartlett, Michael Bilous, Ian O Ellis, Patrick Fitzgibbons, Wedad Hanna, Robert B Jenkins, Michael F Press, Patricia A Spears, Gail H Vance, Giuseppe Viale, Lisa M McShane, and Mitchell Dowsett

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Rational design for cervical cancer therapeutics: cellular and non-cellular based strategies on the horizon for recurrent, metastatic or refractory cervical cancer., Juliet E Wolford and Krishnansu S Tewari

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ALT-803, an IL-15 superagonist, in combination with nivolumab in patients with metastatic non-small cell lung cancer: a non-randomised, open-label, phase 1b trial., John M Wrangle, Vamsidhar Velcheti, Manish R Patel, Elizabeth Garrett-Mayer, Elizabeth G Hill, James G Ravenel, Jeffrey S Miller, Mohammad Farhad, Kate Anderton, Kathryn Lindsey, Michele Taffaro-Neskey, Carol Sherman, Samantha Suriano, Marzena Swiderska-Syn, Amy Sion, Joni Harris, Andie R Edwards, Julie A Rytlewski, Catherine M Sanders, Erik C Yusko, Mark D Robinson, Carsten Krieg, William L Redmond, Jack O Egan, Peter R Rhode, Emily K Jeng, Amy D Rock, Hing C Wong, and Mark P Rubinstein

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Recurrent tumor-specific regulation of alternative polyadenylation of cancer-related genes., Zhuyi Xue, René L Warren, Ewan A Gibb, Daniel MacMillan, Johnathan Wong, Readman Chiu, S Austin Hammond, Chen Yang, Ka Ming Nip, Catherine A Ennis, Abigail Hahn, Sheila Reynolds, and Inanc Birol

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Whole-Mount Adult Ear Skin Imaging Reveals Defective Neuro-Vascular Branching Morphogenesis in Obese and Type 2 Diabetic Mouse Models., Tomoko Yamazaki, Wenling Li, Ling Yang, Ping Li, Haiming Cao, Sei-Ichiro Motegi, Mark C Udey, Elise Bernhard, Takahisa Nakamura, and Yoh-Suke Mukouyama

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Tissue Specific Origin, Development, and Pathological Perspectives of Pericytes., Tomoko Yamazaki and Yoh-Suke Mukouyama

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Molecular subgroups and B7-H4 expression levels predict responses to dendritic cell vaccines in glioblastoma: an exploratory randomized phase II clinical trial., Yu Yao, Feifei Luo, Chao Tang, Dikang Chen, Zhiyong Qin, Wei Hua, Ming Xu, Ping Zhong, Shuangquan Yu, Di Chen, Xiaojie Ding, Yi Zhang, Xiujuan Zheng, Jiao Yang, Jiawen Qian, Yuting Deng, Dave S B Hoon, Jian Hu, Yiwei Chu, and Liangfu Zhou

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Enhanced detection of neoantigen-reactive T cells targeting unique and shared oncogenes for personalized cancer immunotherapy., Rami Yossef, Eric Tran, Drew C Deniger, Alena Gros, Anna Pasetto, Maria R Parkhurst, Jared J Gartner, Todd D Prickett, Gal Cafri, Paul F Robbins, and Steven A Rosenberg

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P16-positive cystic squamous cell carcinoma in midline neck: metastasis from oropharynx or primary carcinoma arising from thyroglossal duct cyst?, Songlin Zhang, Hong D Xiao, Zhenjian Cai, Michael Covinsky, Karan Saluja, Maria O Patino, Xinmin Liu, and Hui Zhu

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Vx3-Functionalized Alumina Nanoparticles Assisted Enrichment of Ubiquitinated Proteins from Cancer Cells for Enhanced Cancer Immunotherapy., Jinjin Zhao, Ning Pan, Fang Huang, Mohanad Aldarouish, Zhifa Wen, Rong Gao, Yuye Zhang, Hong-Ming Hu, Yanfei Shen, and Li-Xin Wang

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Author Correction: Extracting Intercellular Signaling Network of Cancer Tissues using Ligand-Receptor Expression Patterns from Whole-tumor and Single-cell Transcriptomes., Joseph X Zhou, Roberto Taramelli, Edoardo Pedrini, Theo Knijnenburg, and Sui Huang

Submissions from 2017

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New Cancer Immunotherapy Agents in Development: a report from an associated program of the 31, Prasad S Adusumilli, Edward Cha, Mark Cornfeld, Thomas Davis, Adi Diab, Thomas W Dubensky, Elizabeth Evans, Jane L Grogan, Bryan A Irving, Rom Leidner, Shane A Olwill, Patrick Soon-Shiong, Frederic Triebel, David Tuck, Adrian Bot, Roger D Dansey, Charles G Drake, Gordon J Freeman, Ramy Ibrahim, Salil Patel, and Daniel S Chen