The Cancer Institute is a leader in cutting-edge treatments. Using a truly multidisciplinary approach, patients have access to advanced diagnostics, minimally invasive surgical interventions, and personalized genomic and immune-oncologic treatment options. Our team of cancer specialists – many of whom completed fellowships and specialty training at prestigious academic centers – offers comprehensive services for individuals with a cancer diagnosis.

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Submissions from 2018

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Tumor cell-released autophagosomes (TRAP) enhance apoptosis and immunosuppressive functions of neutrophils., Rong Gao, Jie Ma, Zhifa Wen, Peiying Yang, Jinjin Zhao, Meng Xue, Yongqiang Chen, Mohanad Aldarouish, Hong-Ming Hu, Xue-Jun Zhu, Ning Pan, and Li-Xin Wang

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Randomized phase II study of fulvestrant and erlotinib compared with erlotinib alone in patients with advanced or metastatic non-small cell lung cancer., Edward B Garon, Jill M Siegfried, Laura P Stabile, Patricia A Young, Diana C Marquez-Garban, David J Park, Ravi Patel, Eddie H Hu, Saeed Sadeghi, Rupesh J Parikh, Karen L Reckamp, Brad Adams, Robert M Elashoff, David Elashoff, Tristan Grogan, He-Jing Wang, Sanja Dacic, Meghan Brennan, Yacgley Valdes, Simon Davenport, Steven M Dubinett, Michael F Press, Dennis J Slamon, and Richard J Pietras

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Pathologists' Use of Second Opinions in Interpretation of Melanocytic Cutaneous Lesions: Policies, Practices, and Perceptions., Berta M Geller, Paul D Frederick, Stevan R Knezevich, Jason P Lott, Heidi D Nelson, Linda J Titus, Patricia A Carney, Anna N A Tosteson, Tracy L Onega, Raymond L Barnhill, Martin A Weinstock, David E Elder, Michael W Piepkorn, and Joann G Elmore

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Voxel-Wise Analysis of Fluoroethyltyrosine PET and MRI in the Assessment of Recurrent Glioblastoma During Antiangiogenic Therapy., Elizabeth George, Marie F Kijewski, Shipra Dubey, Anthony P Belanger, David A Reardon, Patrick Y Wen, Santosh Kesari, Laura Horky, Mi-Ae Park, and Raymond Y Huang

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Randomized phase III study of docetaxel plus bavituximab in previously treated advanced non-squamous non-small-cell lung cancer., D E Gerber, L Horn, M Boyer, Rachel E Sanborn, R Natale, R Palmero, P Bidoli, I Bondarenko, P Germonpre, D Ghizdavescu, A Kotsakis, H Lena, G Losonczy, K Park, W-C Su, M Tang, J Lai, N L Kallinteris, J S Shan, M Reck, and D R Spigel

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A Placebo-Controlled Phase II Study of Ruxolitinib in Combination With Pemetrexed and Cisplatin for First-Line Treatment of Patients With Advanced Nonsquamous Non-Small-Cell Lung Cancer and Systemic Inflammation., Giuseppe Giaccone, Rachel E Sanborn, Saiama N Waqar, Alex Martinez-Marti, Santiago Ponce, Huiling Zhen, Gerard Kennealey, Susan Erickson-Viitanen, and Eric Schaefer

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The Impact of the ASAP Trial: Maybe We Shouldn't Act So Quickly., Christopher R Gilbert, Jason A Akulian, and Jed A Gorden

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The decision to biopsy in a lung cancer screening program: Potential impact of risk calculators., Christopher R Gilbert, Alexander S Carlson, Candice L. Wilshire, Ralph W Aye, Alexander S Farivar, Adam J Bograd, and Jed A Gorden

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The economic impact of a nurse practitioner-directed lung cancer screening, incidental pulmonary nodule, and tobacco-cessation clinic., Christopher R Gilbert, Rob Ely, Joelle T Fathi, Brian E Louie, Candice L. Wilshire, Hannah Modin, Ralph W Aye, Alexander S Farivar, Eric Vallières, and Jed A Gorden

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Impact of latency time on survival for adolescents and young adults with a second primary malignancy., Melanie Goldfarb, Aaron S Rosenberg, Qian Li, and Theresa H M Keegan

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TP73 DNA methylation and upregulation of ΔNp73 are associated with an adverse prognosis in breast cancer, Laura C Gomez, Mayra L Sottile, Martin E Guerrero-Gimenez, Felipe C M Zoppino, Analia L Redondo, Francisco E Gago, Javier I Orozco, Olga M Tello, Maria Roqué, Silvina B Nadin, Diego M Marzese, and Laura M Vargas-Roig

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Oncofertility in the setting of advanced cervical cancer - A case report., Catherine Gordon, Joseph C Carmichael, and Krishnansu S Tewari

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Implantable biomaterials to provide local immunotherapy following surgical resection., Michael J Gough, Jason R Baird, and R Bryan Bell

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Inducible T cell Co-stimulator (ICOS) is upregulated on lymphocytes following radiation of tumors and ICOS agonism in combination with radiation results in enhanced tumor control, Michael J. Gough, Shelly Bambina, Monica Gostissa, Christopher Harvey, David Friedman, and Marka R Crittenden

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Leptomeningeal Metastases., Jerome J Graber and Santosh Kesari

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Epigenomic and Transcriptomic Characterization of Secondary Breast Cancers., Amanda N Graff-Baker, Javier I Orozco, Diego M Marzese, Matthew P Salomon, Dave S B Hoon, and Melanie Goldfarb

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TumorNext-Lynch-MMR: a comprehensive next generation sequencing assay for the detection of germline and somatic mutations in genes associated with mismatch repair deficiency and Lynch syndrome., Phillip N Gray, Pei Tsai, Daniel Chen, Sitao Wu, Jayne Hoo, Wenbo Mu, Bing Li, Huy Vuong, Hsiao-Mei Lu, Navanjot Batth, Sara Willett, Lisa Uyeda, Swati Shah, Chia-Ling Gau, Monalyn Umali, Carin Espenschied, Mike Janicek, Sandra Brown, David Margileth, Lavinia Dobrea, Lawrence Wagman, Huma Rana, Michael J Hall, Theodora Ross, Jonathan Terdiman, Carey Cullinane, Savita Ries, Ellen Totten, and Aaron M Elliott

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Challenges to Educating Smokers About Lung Cancer Screening: a Qualitative Study of Decision Making Experiences in Primary Care., Preston A Greene, George Sayre, Jaimee L Heffner, Deborah E Klein, Paul Krebs, David H Au, and Steven B Zeliadt

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Phase II Feasibility Study of a Weight Loss Intervention in Female Breast and Colorectal Cancer Survivors (SWOG S1008)., Heather Greenlee, Danika L Lew, Dawn L Hershman, Vicky A Newman, Lisa Hansen, Sheri J Hartman, Judith Korner, Zaixing Shi, Christine L Sardo Molmenti, Antoine Sayegh, Lou Fehrenbacher, Shelly Lo, Jennifer Klemp, Kristine Rinn, John M Robertson, Joseph Unger, Julie Gralow, Kathy Albain, Robert Krouse, and Carol Fabian

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Clinical trial experience with CA4P anticancer therapy: focus on efficacy, cardiovascular adverse events, and hypertension management., Rachel Grisham, Bonnie Ky, Krishnansu S Tewari, David J Chaplin, and Joan Walker

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Loss of inter-cellular cooperation by complete epithelial-mesenchymal transition supports favorable outcomes in basal breast cancer patients., Anne Grosse-Wilde, Rolf E Kuestner, Stephanie M Skelton, Ellie MacIntosh, Aymeric Fouquier d'Hérouël, Gökhan Ertaylan, Antonio Del Sol, Alexander Skupin, and Sui Huang

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Aberrant Lck Signal via CD28 Costimulation Augments Antigen-Specific Functionality and Tumor Control by Redirected T Cells with PD-1 Blockade in Humanized Mice., Pratiksha Gulati, Julia Rühl, Abhilash Kannan, Magdalena Pircher, Petra Schuberth, Katarzyna J Nytko, Martin Pruschy, Simon Sulser, Mark Haefner, Shawn Jensen, Alex Soltermann, Wolfgang Jungraithmayr, Maya Eisenring, Thomas Winder, Panagiotis Samaras, Annett Tabor, Rene Stenger, Roger Stupp, Walter Weder, Christoph Renner, Christian Münz, and Ulf Petrausch

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Exploring optimal sequencing of radiation and immunotherapy combinations., Andrew J Gunderson and Kristina H Young

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Plasma vs Tissue Next-Generation Sequencing in Non-Small Cell Lung Cancer-Either, Both, or Neither?, Bishal Gyawali and Howard Jack West

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Regional Thoracic Surgery Quality Collaboration Formation: Providence Thoracic Surgery Initiative., John R Handy, Kimberly Costas, Robert McKenna, Steven Nisco, Raymond Schaerf, Kenton Stephens, Eric Vallières, Kasia Konieczny, Roshanthi Weerasinghe, Mansen Wang, Katherine Lothrop, and Cathy Betzer

Where's the Money? Revenues associated with 3000 Lung Cancer Screens, John Handy Jr., Courtney Wood, Erika Rauch, Kevin Olson, Roshanthi Weerasinghe, Rachel Sanborn, and Micheal Skokan

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Expert Consensus Document on Pulmonary Metastasectomy., J R Handy, R M Bremner, T S Crocenzi, F C Detterbeck, H C Fernando, P M Fidias, S Firestone, C A Johnstone, M Lanuti, V R Litle, K A Kesler, J D Mitchell, H I Pass, H J Ross, and T K Varghese

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Prognostic Value of ACVRL1 Expression in Metastatic Colorectal Cancer Patients Receiving First-line Chemotherapy With Bevacizumab: Results From the Triplet Plus Bevacizumab (TRIBE) Study., Diana L Hanna, Fotios Loupakis, Dongyun Yang, Chiara Cremolini, Marta Schirripa, Meng Li, Satoshi Matsusaka, Martin D Berger, Yuji Miyamoto, Wu Zhang, Yan Ning, Carlotta Antoniotti, Lisa Salvatore, Miriana Moran, Gary Zeger, Stephanie H Astrow, Alfredo Falcone, and Heinz-Josef Lenz

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Meta-Analysis of Local Invasive Breast Cancer Recurrence After Electron Intraoperative Radiotherapy., Jay K Harness, Kalatu Davies, Christina Via, Elizabeth Brooks, April Zambelli-Weiner, Chirag Shah, and Frank Vicini

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ASO Author Reflections: Meta-Analysis of Local Recurrence of Invasive Breast Cancer After Electron Intraoperative Radiotherapy., Jay K Harness and Chirag Shah

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Expression of LC3B and FIP200/Atg17 in brain metastases of breast cancer., Nooshin Hashemi-Sadraei, Gaëlle M Müller-Greven, Fadi W Abdul-Karim, Ilya Ulasov, Erinn Downs-Kelly, Monica E Burgett, Adam Lauko, Maha A Qadan, Robert J Weil, Manmeet S Ahluwalia, Lingling Du, Richard A Prayson, Samuel T Chao, Thomas G Budd, Jill Barnholtz-Sloan, Amy S Nowacki, Ruth A Keri, and Candece L Gladson

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Rethinking medulloblastoma from a targeted therapeutics perspective., Yuuri Hashimoto, Marta Penas-Prado, Shouhao Zhou, Jun Wei, Soumen Khatua, Tiffany R Hodges, Nader Sanai, Joanne Xiu, Zoran Gatalica, Lyndon Kim, Santosh Kesari, Ganesh Rao, David Spetzler, and Amy Heimberger

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Smokers' Inaccurate Beliefs about the Benefits of Lung Cancer Screening., Jaimee L Heffner, Paul Krebs, Hannah Johnson, Preston A Greene, Deborah E Klein, Laura C Feemster, Christopher G Slatore, David H Au, and Steven B Zeliadt

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Catheter-Related Thrombosis in Patients with Lymphoma or Myeloma Undergoing Autologous Stem Cell Transplantation., Livia Hegerova, Adam Bachan, Qing Cao, Huong X Vu, John Rogosheske, Mark T Reding, Claudio G Brunstein, Mukta Arora, Celalettin Ustun, Gregory M Vercellotti, and Veronika Bachanova

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Mindfulness-Based Interventions for Hematology and Oncology Patients with Pain., Denise Hess

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Integrative Molecular Characterization of Malignant Pleural Mesothelioma., Julija Hmeljak, Francisco Sanchez-Vega, Katherine A Hoadley, Juliann Shih, Chip Stewart, David Heiman, Patrick Tarpey, Ludmila Danilova, Esther Drill, Ewan A Gibb, Reanne Bowlby, Rupa Kanchi, Hatice U Osmanbeyoglu, Yoshitaka Sekido, Jumpei Takeshita, Yulia Newton, Kiley Graim, Manaswi Gupta, Carl M Gay, Lixia Diao, David L Gibbs, Vesteinn Thorsson, Lisa Iype, Havish Kantheti, David T Severson, Gloria Ravegnini, Patrice Desmeules, Achim A Jungbluth, William D Travis, Sanja Dacic, Lucian R Chirieac, Françoise Galateau-Sallé, Junya Fujimoto, Aliya N Husain, Henrique C Silveira, Valerie W Rusch, Robert C Rintoul, Harvey Pass, Hedy Kindler, Marjorie G Zauderer, David J Kwiatkowski, Raphael Bueno, Anne S Tsao, Jenette Creaney, Tara Lichtenberg, Kristen Leraas, Jay Bowen, Ina Felau, Jean Claude Zenklusen, Rehan Akbani, Andrew D Cherniack, Lauren A Byers, Michael S Noble, Jonathan A Fletcher, A Gordon Robertson, Ronglai Shen, Hiroyuki Aburatani, Bruce W Robinson, Peter Campbell, and Marc Ladanyi

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Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer., Katherine A Hoadley, Christina Yau, Toshinori Hinoue, Denise M Wolf, Alexander J Lazar, Esther Drill, Ronglai Shen, Alison M Taylor, Andrew D Cherniack, Vésteinn Thorsson, Rehan Akbani, Reanne Bowlby, Christopher K Wong, Maciej Wiznerowicz, Francisco Sanchez-Vega, A Gordon Robertson, Barbara G Schneider, Michael S Lawrence, Houtan Noushmehr, Tathiane M Malta, Joshua M Stuart, Christopher C Benz, and Peter W Laird

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Early loss of Histone H2B monoubiquitylation alters chromatin accessibility and activates key immune pathways that facilitate progression of ovarian cancer., Jagmohan Hooda, Marian Novak, Matthew P Salomon, Chikako Matsuba, Romela I Ramos, Emily MacDuffie, Melissa Song, Michelle S Hirsch, Jenny Lester, Vinita Parkash, Beth Y Karlan, Moshe Oren, Dave S B Hoon, and Ronny Drapkin

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Ensartinib (X-396) in ALK-Positive Non-Small Cell Lung Cancer: Results from a First-in-Human Phase I/II, Multicenter Study., Leora Horn, Jeffrey R Infante, Karen L Reckamp, George R Blumenschein, Ticiana A Leal, Saiama N Waqar, Barbara J Gitlitz, Rachel E Sanborn, Jennifer G Whisenant, Liping Du, Joel W Neal, Jon P Gockerman, Gary Dukart, Kimberly Harrow, Chris Liang, James J Gibbons, Allison Holzhausen, Christine M Lovly, and Heather A Wakelee

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New and Important Changes in the TNM Staging System for Breast Cancer., Gabriel N Hortobagyi, Stephen B Edge, and Armando Giuliano

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Pathogenic Germline Variants in 10,389 Adult Cancers., Kuan-Lin Huang, R Jay Mashl, Yige Wu, Deborah I Ritter, Jiayin Wang, Clara Oh, Marta Paczkowska, Sheila Reynolds, Matthew A Wyczalkowski, Ninad Oak, Adam D Scott, Michal Krassowski, Andrew D Cherniack, Kathleen E Houlahan, Reyka Jayasinghe, Liang-Bo Wang, Daniel Cui Zhou, Di Liu, Song Cao, Young Won Kim, Amanda Koire, Joshua F McMichael, Vishwanathan Hucthagowder, Tae-Beom Kim, Abigail Hahn, Chen Wang, Michael D McLellan, Fahd Al-Mulla, Kimberly J Johnson, Olivier Lichtarge, Paul C Boutros, Benjamin Raphael, Alexander J Lazar, Wei Zhang, Michael C Wendl, Ramaswamy Govindan, Sanjay Jain, David Wheeler, Shashikant Kulkarni, John F Dipersio, Jüri Reimand, Funda Meric-Bernstam, Ken Chen, Ilya Shmulevich, Sharon E Plon, Feng Chen, and Li Ding

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Single cell sequencing to identify TCRs that recognize autologous tumor cells after vaccination with allogeinic DRibble vaccine, Hong-Ming Hu, Christopher C. Paustian, Zhifa Wen, Tarsem L. Moudgil, Traci L. Hilton, Sam Bookhardt, Guangjie Yu, Eric Tran, Venkatesh Rajamanickam, Walter Urba, Rachel E. Sanborn, and Bernard A. Fox

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Coordinated responses to individual tumor antigens by IgG antibody and CD8+ T cells following cancer vaccination., Tyler W Hulett, Shawn M. Jensen, Phillip A Wilmarth, Ashok P Reddy, Carmen Ballesteros-Merino, Michael E Afentoulis, Christopher Dubay, Larry L David, and Bernard A Fox

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Internal and External Validation of a 90-Day Percentage Erection Fullness Score Model Predicting Potency Recovery Following Robot-assisted Radical Prostatectomy., Linda M Huynh, Douglas Skarecky, Timothy Wilson, Clayon Lau, Christian Wagner, James R Porter, Jorn H Witt, and Thomas E Ahlering

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Protection from chemotherapy- and antibiotic-mediated dysbiosis of the gut microbiota by a probiotic with digestive enzymes supplement., Thomas E Ichim, Santosh Kesari, and Kim Shafer

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Predominance of triple wild-type and IGF2R mutations in mucosal melanomas., Yuuki Iida, Matthew P Salomon, Keisuke Hata, Kevin Tran, Shuichi Ohe, Chester Griffiths, Sandy C Hsu, Nellie Nelson, and Dave S B Hoon

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The Metastatic Microenvironment: Melanoma-Microglia Cross-Talk Promotes the Malignant Phenotype of Melanoma Cells., Sivan Izraely, Shlomit Ben-Menachem, Orit Sagi-Assif, Alona Telerman, Inna Zubrilov, Ofir Ashkenazi, Tsipi Meshel, Shelly Maman, Javier I J Orozco, Matthew P Salomon, Diego M Marzese, Metsada Pasmanik-Chor, Eli Pikarsky, Marcelo Ehrlich, Dave S B Hoon, and Isaac P Witz

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Endoscopic Approaches to Cricopharyngeal Myotomy and Pyloromyotomy., Anee Sophia Jackson and Ralph W Aye

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Management of complex pleural space infections: as the pendulum swings European Respiratory Society International Congress 2018 Paris, France, AS Jackson, Candice L. Wilshire, and See all authors in comments

Treatment of surveillance detected disease after resection of primary non-small cell lung cancer The 26th European Conference on General Thoracic Surgery Ljubljana, Slovenia, AS Jackson, Candice L. Wilshire, and See all authors in comments

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Variable adoption of intrapleural fibrinolytic therapy for pleural space infections European Respiratory Society International Congress 2018 Paris, France, AS Jackson, Candice L. Wilshire, and See all authors in comments

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Systematic Analysis of Splice-Site-Creating Mutations in Cancer., Reyka G Jayasinghe, Song Cao, Qingsong Gao, Michael C Wendl, Nam Sy Vo, Sheila M Reynolds, Yanyan Zhao, Héctor Climente-González, Shengjie Chai, Fang Wang, Rajees Varghese, Mo Huang, Wen-Wei Liang, Matthew A Wyczalkowski, Sohini Sengupta, Zhi Li, Samuel H Payne, David Fenyö, Jeffrey H Miner, Matthew J Walter, Benjamin Vincent, Eduardo Eyras, Ken Chen, Ilya Shmulevich, Feng Chen, and Li Ding

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Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk., Xuemei Ji, Yohan Bossé, Maria Teresa Landi, Jiang Gui, Xiangjun Xiao, David Qian, Philippe Joubert, Maxime Lamontagne, Yafang Li, Ivan Gorlov, Mariella de Biasi, Younghun Han, Olga Gorlova, Rayjean J Hung, Xifeng Wu, James McKay, Xuchen Zong, Robert Carreras-Torres, David C Christiani, Neil Caporaso, Mattias Johansson, Geoffrey Liu, Stig E Bojesen, Loic Le Marchand, Demetrios Albanes, Heike Bickeböller, Melinda C Aldrich, William S Bush, Adonina Tardon, Gad Rennert, Chu Chen, M Dawn Teare, John K Field, Lambertus A Kiemeney, Philip Lazarus, Aage Haugen, Stephen Lam, Matthew B Schabath, Angeline S Andrew, Hongbing Shen, Yun-Chul Hong, Jian-Min Yuan, Pier A Bertazzi, Angela C Pesatori, Yuanqing Ye, Nancy Diao, Li Su, Ruyang Zhang, Yonathan Brhane, Natasha Leighl, Jakob S Johansen, Anders Mellemgaard, Walid Saliba, Christopher Haiman, Lynne Wilkens, Ana Fernandez-Somoano, Guillermo Fernandez-Tardon, Erik H F M van der Heijden, Jin Hee Kim, Juncheng Dai, Zhibin Hu, Michael P A Davies, Michael W Marcus, Hans Brunnström, Jonas Manjer, Olle Melander, David C Muller, Kim Overvad, Antonia Trichopoulou, Rosario Tumino, Jennifer Doherty, Gary E Goodman, Angela Cox, Fiona Taylor, Penella Woll, Irene Brüske, Judith Manz, Thomas Muley, Angela Risch, Albert Rosenberger, Kjell Grankvist, Mikael Johansson, Frances Shepherd, Ming-Sound Tsao, Susanne M Arnold, Eric B Haura, Ciprian Bolca, Ivana Holcatova, Vladimir Janout, Milica Kontic, Jolanta Lissowska, Anush Mukeria, Simona Ognjanovic, Tadeusz M Orlowski, Ghislaine Scelo, Beata Swiatkowska, David Zaridze, Per Bakke, Vidar Skaug, Shanbeh Zienolddiny, Eric J Duell, Lesley M Butler, Woon-Puay Koh, Yu-Tang Gao, Richard Houlston, John McLaughlin, Victoria Stevens, David C Nickle, Ma'en Obeidat, Wim Timens, Bin Zhu, Lei Song, María Soler Artigas, Martin D Tobin, Louise V Wain, Fangyi Gu, Jinyoung Byun, Ahsan Kamal, Dakai Zhu, Rachel F Tyndale, Wei-Qi Wei, Stephen Chanock, Paul Brennan, and Christopher I Amos

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Unleashing endogenous TNF-alpha as a cancer immunotherapeutic., Steven F Josephs, Thomas E Ichim, Stephen M Prince, Santosh Kesari, Francesco M Marincola, Anton Rolando Escobedo, and Amir Jafri

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Management of complex pleural space infections: as the pendulum swings The American Association for Thoracic Surgery 98th Annual Meeting Resident Poster Competition San Diego, California, NM Kanodra, Candice L. Wilshire, and See all authors in comments

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Pharmacokinetics of dacarbazine (DTIC) in pregnancy., Ira Kantrowitz-Gordon, Karen Hays, Olumide Kayode, Aditya R Kumar, Henry G Kaplan, Joel M Reid, Stephanie L Safgren, Matthew M Ames, Thomas R Easterling, and Mary F Hebert

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Genomic Profiling in Patients With Malignant Peripheral Nerve Sheath Tumors Reveals Multiple Pathways With Targetable Mutations., Henry G Kaplan, Steven Rostad, Jeffrey S Ross, Siraj M Ali, and Sherri Z Millis

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Pegzilarginase in combination with agonist anti-OX40 therapy enhances T cell priming and effector function leading to improved tumor regression and survival, Melissa Kasiewicz, Annah Rolig, Elizabeth Sturgill, Mark Badeaux, Scott Rowlinson, and William L. Redmond

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Tamoxifen overrides autophagy inhibition in Beclin-1-deficient glioma cells and their resistance to adenovirus-mediated oncolysis via upregulation of PUMA and BAX., Natalya V Kaverina, Zaira G Kadagidze, Anton V Borovjagin, Apollon I Karseladze, Chung Kwon Kim, Maciej S Lesniak, Jason Miska, Peng Zhang, Maria A Baryshnikova, Ting Xiao, David Ornelles, Charles Cobbs, Andrey Khramtsov, and Ilya V Ulasov

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Applying genomics in heart transplantation., Brendan J Keating, Alexandre C Pereira, Michael Snyder, and Brian D. Piening

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Digitally Recorded Education: Effects on Anxiety and Knowledge Recall in Patients Receiving First-Time Chemotherapy., Kathy A Keener and Elizabeth J Winokur

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Phase I Study of the Investigational Aurora A Kinase Inhibitor Alisertib plus Rituximab or Rituximab/vincristine in Relapsed/refractory Aggressive B-cell Lymphoma., Kevin R Kelly, Jonathan W Friedberg, Steven I Park, Kevin T McDonagh, John Hayslip, Daniel Persky, Jia Ruan, Soham Puvvada, Peter J Rosen, Swaminathan Padmanabhan Iyer, Alexandra Stefanovic, Steven H Bernstein, Steven Weitman, Anand B Karnad, Gregory Monohan, Ari VanderWalde, Raul Mena, Monika Schmelz, Catherine Spier, Susan Groshen, Karthik Venkatakrishnan, Xiaofei Zhou, Emily Sheldon-Waniga, E Jane Leonard, and Daruka Mahadevan

A Tale of Two Bladders- High-Grade Non-muscle Invasive Bladder Cancer and Muscle Invasive Bladder Cancer: Evolving treatment paradigms, Mark J. Kelly

Focal Ablation for Locally Advance Prostate Cancer, Mark J. Kelly

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Functional Anatomic Computer Engineered Surgery Protocol for the Management of Self-Inflicted Gunshot Wounds to the Maxillofacial Skeleton., Baber Khatib, Karl Cuddy, Allen Cheng, Ashish Patel, Felix Sim, Melissa Amundson, Savannah Gelesko, Tuan Bui, Eric J Dierks, and Richard Bryan Bell

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The Radial Forearm Flap: A Technique Modification for Oral Cavity Composite Defects Involving a Marginal Mandibulectomy., Baber Khatib, Ashish Patel, Eric J Dierks, and Allen Cheng

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Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas., Theo A Knijnenburg, Linghua Wang, Michael T Zimmermann, Nyasha Chambwe, Galen F Gao, Andrew D Cherniack, Huihui Fan, Hui Shen, Gregory P Way, Casey S Greene, Yuexin Liu, Rehan Akbani, Bin Feng, Lawrence A Donehower, Chase Miller, Yang Shen, Mostafa Karimi, Haoran Chen, Pora Kim, Peilin Jia, Eve Shinbrot, Shaojun Zhang, Jianfang Liu, Hai Hu, Matthew H Bailey, Christina Yau, Denise Wolf, Zhongming Zhao, John N Weinstein, Lei Li, Li Ding, Gordon B Mills, Peter W Laird, David A Wheeler, Ilya Shmulevich, Raymond J Monnat, Yonghong Xiao, and Chen Wang

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Authentication of M14 melanoma cell line proves misidentification of MDA-MB-435 breast cancer cell line., Christopher Korch, Erin M Hall, Wilhelm G Dirks, Margaret Ewing, Mark Faries, Marileila Varella-Garcia, Steven Robinson, Douglas Storts, Jacqueline A Turner, Ying Wang, Edward C Burnett, Lyn Healy, Douglas Kniss, Richard M Neve, Raymond W Nims, Yvonne A Reid, William A Robinson, and Amanda Capes-Davis

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Reprogrammed lipid metabolism in bladder cancer with cisplatin resistance., Min Young Lee, Austin Yeon, Muhammad Shahid, Eunho Cho, Vikram Sairam, Robert Figlin, Khae-Hwan Kim, and Jayoung Kim

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Growth hormone-secreting pituitary macroadenoma presenting concurrently with non-Hodgkin's lymphoma and responding to doxorubicin treatment: case report and review of the literature., Gregory P Lekovic, Asheesh Batra, Zachary R Barnard, Eric P Wilkinson, Richard Balena, Sheri Palejwala, and Garni Barkhoudarian

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Novel frontiers in detecting cancer metastasis., Stanley P Leong, Carmen Ballesteros-Merino, Shawn M Jensen, Sebastian Marwitz, Carlo Bifulco, Bernard A Fox, and Mojca Skoberne

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Transversus Abdominis Plane Block Improves Perioperative Outcome After Esophagectomy Versus Epidural., Gal Levy, Mark A Cordes, Alexander S Farivar, Ralph W Aye, and Brian E Louie

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First results on survival from a large Phase 3 clinical trial of an autologous dendritic cell vaccine in newly diagnosed glioblastoma., Linda M Liau, Keyoumars Ashkan, David D Tran, Jian L Campian, John E Trusheim, Charles S Cobbs, Jason A Heth, Michael Salacz, Sarah Taylor, Stacy D D'Andre, Fabio M Iwamoto, Edward J Dropcho, Yaron A Moshel, Kevin A Walter, Clement P Pillainayagam, Robert Aiken, Rekha Chaudhary, Samuel A Goldlust, Daniela A Bota, Paul Duic, Jai Grewal, Heinrich Elinzano, Steven A Toms, Kevin O Lillehei, Tom Mikkelsen, Tobias Walbert, Steven R Abram, Andrew J Brenner, Steven Brem, Matthew G Ewend, Simon Khagi, Jana Portnow, Lyndon J Kim, William G Loudon, Reid C Thompson, David E Avigan, Karen L Fink, Francois J Geoffroy, Scott Lindhorst, Jose Lutzky, Andrew E Sloan, Gabriele Schackert, Dietmar Krex, Hans-Jorg Meisel, Julian Wu, Raphael P Davis, Christopher Duma, Arnold B Etame, David Mathieu, Santosh Kesari, David Piccioni, Manfred Westphal, David S Baskin, Pamela Z New, Michel Lacroix, Sven-Axel May, Timothy J Pluard, Victor Tse, Richard M Green, John L Villano, Michael Pearlman, Kevin Petrecca, Michael Schulder, Lynne P Taylor, Anthony E Maida, Robert M Prins, Timothy F Cloughesy, Paul Mulholland, and Marnix L Bosch

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Detection of Minimal Residual Disease and Its Clinical Applications in Melanoma and Breast Cancer Patients., Selena Y Lin, Javier I J Orozco, and Dave S B Hoon

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SPIO Enhance the Cross-Presentation and Migration of DCs and Anionic SPIO Influence the Nanoadjuvant Effects Related to Interleukin-1β., Hui Liu, Heng Dong, Na Zhou, Shiling Dong, Lin Chen, Yanxiang Zhu, Hong-Ming Hu, and Yongbin Mou

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An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics., Jianfang Liu, Tara Lichtenberg, Katherine A Hoadley, Laila M Poisson, Alexander J Lazar, Andrew D Cherniack, Albert J Kovatich, Christopher C Benz, Douglas A Levine, Adrian V Lee, Larsson Omberg, Denise M Wolf, Craig D Shriver, Vesteinn Thorsson, and Hai Hu

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Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas., Yang Liu, Nilay S Sethi, Toshinori Hinoue, Barbara G Schneider, Andrew D Cherniack, Francisco Sanchez-Vega, Jose A Seoane, Farshad Farshidfar, Reanne Bowlby, Mirazul Islam, Jaegil Kim, Walid Chatila, Rehan Akbani, Rupa S Kanchi, Charles S Rabkin, Joseph E Willis, Kenneth K Wang, Shannon J McCall, Lopa Mishra, Akinyemi I Ojesina, Susan Bullman, Chandra Sekhar Pedamallu, Alexander J Lazar, Ryo Sakai, Vésteinn Thorsson, Adam J Bass, and Peter W Laird

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miR-29c plays a suppressive role in breast cancer by targeting the TIMP3/STAT1/FOXO1 pathway., Wan Li, Jie Yi, Xiangjin Zheng, Shiwei Liu, Weiqi Fu, Liwen Ren, Li Li, Dave S B Hoon, Jinhua Wang, and Guanhua Du

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Genome-wide interaction study of smoking behavior and non-small cell lung cancer risk in Caucasian population., Yafang Li, Xiangjun Xiao, Younghun Han, Olga Gorlova, David Qian, Natasha Leighl, Jakob S Johansen, Matt Barnett, Chu Chen, Gary E Goodman, Angela Cox, Fiona Taylor, Penella Woll, H-Erich Wichmann, Judith Manz, Thomas Muley, Angela Risch, Albert Rosenberger, Susanne M Arnold, Eric B Haura, Ciprian Bolca, Ivana Holcatova, Vladimir Janout, Milica Kontic, Jolanta Lissowska, Anush Mukeria, Simona Ognjanovic, Tadeusz M Orlowski, Ghislaine Scelo, Beata Swiatkowska, David Zaridze, Per Bakke, Vidar Skaug, Shanbeh Zienolddiny, Eric J Duell, Lesley M Butler, Richard Houlston, María Soler Artigas, Kjell Grankvist, Mikael Johansson, Frances A Shepherd, Michael W Marcus, Hans Brunnström, Jonas Manjer, Olle Melander, David C Muller, Kim Overvad, Antonia Trichopoulou, Rosario Tumino, Geoffrey Liu, Stig E Bojesen, Xifeng Wu, Loic Le Marchand, Demetrios Albanes, Heike Bickeböller, Melinda C Aldrich, William S Bush, Adonina Tardon, Gad Rennert, M Dawn Teare, John K Field, Lambertus A Kiemeney, Philip Lazarus, Aage Haugen, Stephen Lam, Matthew B Schabath, Angeline S Andrew, Pier Alberto Bertazzi, Angela C Pesatori, David C Christiani, Neil Caporaso, Mattias Johansson, James D McKay, Paul Brennan, Rayjean J Hung, and Christopher I Amos

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Open-source digital image analysis of whole-slide multiplex immunohistochemistry, Nikhil Lonberg, Carmen Ballesteros-Merino, Shawn Jensen, and Bernard A Fox

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Pharmacokinetic drug evaluation of niraparib for the treatment of ovarian cancer., Teresa C Longoria and Krishnansu S Tewari

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Evaluation of a novel cryoballoon swipe ablation system in bench, porcine, and human esophagus models., B E Louie, W Hofstetter, G Triadafilopoulos, and B L Weusten

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Epirubicin and Ifosfamide with Preoperative Radiation for High-Risk Soft Tissue Sarcomas., Eric Lu, Kelly S Perlewitz, James B Hayden, Arthur Y Hung, Yee-Cheen Doung, Lara E Davis, Atiya Mansoor, John T Vetto, Kevin G Billingsley, Andy Kaempf, Byung Park, and Christopher W Ryan

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Re: "MACRA 2018 and the Virtual Group": Logistics of Participating in a MACRA Virtual Group., Join Y Luh

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Reconciling the Effects of Screening on Prostate Cancer Mortality in the ERSPC and PLCO Trials., Join Y Luh, Steven E Finkelstein, Jeff M Michalski, and Howard Sandler

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Follow the trail: Using insights from the growth of palliative care to propose a roadmap for cancer rehabilitation., Kathleen D Lyons, Lynne S Padgett, Timothy F Marshall, Joseph A Greer, Julie K Silver, Vishwa S Raj, David S Zucker, Jack B Fu, Mackenzi Pergolotti, Alix G Sleight, and Catherine M Alfano

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Art and Challenges of Precision Medicine: Interpreting and Integrating Genomic Data Into Clinical Practice., Subha Madhavan, Somasundaram Subramaniam, Thomas D Brown, and James L Chen

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PD-L1 expression with immune-infiltrate evaluation and outcome prediction in melanoma patients treated with ipilimumab., Gabriele Madonna, Carmen Ballesteros-Merino, Zipei Feng, Carlo Bifulco, Mariaelena Capone, Diana Giannarelli, Domenico Mallardo, Ester Simeone, Antonio M Grimaldi, Corrado Caracò, Gerardo Botti, Bernard A Fox, and Paolo A Ascierto

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Testicular tumors in prepubescent patients., Ilan I Maizlin, Matthew Dellinger, Kenneth W Gow, Adam B Goldin, Melanie Goldfarb, Jed G Nuchtern, Monica Langer, Sanjeev A Vasudevan, John J Doski, Mehul V Raval, and Elizabeth A Beierle

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Differential presentation and survival of de novo and recurrent metastatic breast cancer over time: 1990-2010., Judith A Malmgren, Musa Mayer, Mary K Atwood, and Henry G Kaplan

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Examination of a paradox: recurrent metastatic breast cancer incidence decline without improved distant disease survival: 1990-2011., Judith Malmgren, Marc Hurlbert, Mary Atwood, and Henry G Kaplan

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Starting the Fight in the Tumor: Expert Recommendations for the Development of Human Intratumoral Immunotherapy (HIT-IT)., A Marabelle, R Andtbacka, K Harrington, I Melero, R Leidner, T de Baere, C Robert, P A Ascierto, J-F Baurain, M Imperiale, S Rahimian, D Tersago, E Klumper, M Hendriks, R Kumar, M Stern, K Öhrling, C Massacesi, I Tchakov, A Tse, J-Y Douillard, J Tabernero, J Haanen, and J Brody

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Anticancer activity study of A, Gabriella Marucci, Claudia Santinelli, Michela Buccioni, Aleix Martí Navia, Catia Lambertucci, Anastasia Zhurina, Olli Yli-Harja, Rosaria Volpini, and Meenakshisundaram Kandhavelu

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Alternative splicing and cancer metastasis: prognostic and therapeutic applications., Diego M Marzese, Ayla O Manughian-Peter, Javier I J Orozco, and Dave S B Hoon

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Modular Organization and Assembly of SWI/SNF Family Chromatin Remodeling Complexes., Nazar Mashtalir, Andrew R D'Avino, Brittany C Michel, Jie Luo, Joshua Pan, Jordan E Otto, Hayley J Zullow, Zachary M McKenzie, Rachel L Kubiak, Roodolph St Pierre, Alfredo M Valencia, Steven J Poynter, Seth H Cassel, Jeffrey A Ranish, and Cigall Kadoch

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Does treatment of the hiatus influence the outcomes of magnetic sphincter augmentation for chronic GERD? The Society of Surgery of the Alimentary Tract, 59th Annual Meeting Digestive Diseases Week, M Matias, S Blitz, Candice L. Wilshire, AS Jackson, AS Farivar, RW Aye, CM Dunst, and BE Louie

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Venetoclax As Monotherapy or in Combination: Patterns of Use and Predictors of Outcomes in an International Multicenter Study of CLL Patients, Anthony R. Mato, John M Pagel, Neil Bailey, and See all authors in comments

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Outcomes of front-line ibrutinib treated CLL patients excluded from landmark clinical trial., Anthony R Mato, Lindsey E Roeker, John N Allan, John M Pagel, Danielle M Brander, Brian T Hill, Bruce D Cheson, Richard R Furman, Nicole Lamanna, Constantine S Tam, Sasanka Handunnetti, Ryan Jacobs, Frederick Lansigan, Erica Bhavsar, Paul M Barr, Mazyar Shadman, Alan P Skarbnik, Andre Goy, Douglas F Beach, Jakub Svoboda, Jeffrey J Pu, Alison R Sehgal, Clive S Zent, Hande H Tuncer, Stephen J Schuster, Peter V Pickens, Nirav N Shah, Joanna Rhodes, Chaitra S Ujjani, and Chadi Nabhan

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Real world outcomes and management strategies for venetoclax-treated chronic lymphocytic leukemia patients in the United States., Anthony R Mato, Meghan Thompson, John N Allan, Danielle M Brander, John M Pagel, Chaitra S Ujjani, Brian T Hill, Nicole Lamanna, Frederick Lansigan, Ryan Jacobs, Mazyar Shadman, Alan P Skarbnik, Jeffrey J Pu, Paul M Barr, Alison R Sehgal, Bruce D Cheson, Clive S Zent, Hande H Tuncer, Stephen J Schuster, Peter V Pickens, Nirav N Shah, Andre Goy, Allison M Winter, Christine Garcia, Kaitlin Kennard, Krista Isaac, Colleen Dorsey, Lisa M Gashonia, Arun K Singavi, Lindsey E Roeker, Andrew Zelenetz, Annalynn Williams, Christina Howlett, Hanna Weissbrot, Naveed Ali, Sirin Khajavian, Andrea Sitlinger, Eve Tranchito, Joanna Rhodes, Joshua Felsenfeld, Neil Bailey, Bhavisha Patel, Timothy F Burns, Melissa Yacur, Mansi Malhotra, Jakub Svoboda, Richard R Furman, and Chadi Nabhan

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American Association of Physicists in Medicine Task Group 263: Standardizing Nomenclatures in Radiation Oncology., Charles S Mayo, Jean M Moran, Walter Bosch, Ying Xiao, Todd McNutt, Richard Popple, Jeff Michalski, Mary Feng, Lawrence B Marks, Clifton D Fuller, Ellen Yorke, Jatinder Palta, Peter E Gabriel, Andrea Molineu, Martha M Matuszak, Elizabeth Covington, Kathryn Masi, Susan L Richardson, Timothy Ritter, Tomasz Morgas, Stella Flampouri, Lakshmi Santanam, Joseph A Moore, Thomas G Purdie, Robert C Miller, Coen Hurkmans, Judy Adams, Qing-Rong Jackie Wu, Colleen J Fox, Ramon Alfredo Siochi, Norman L Brown, Wilko Verbakel, Yves Archambault, Steven J Chmura, Andre L Dekker, Don G Eagle, Thomas J Fitzgerald, Theodore Hong, Rishabh Kapoor, Beth Lansing, Shruti Jolly, Mary E Napolitano, James Percy, Mark S Rose, Salim Siddiqui, Christof Schadt, William E Simon, William L Straube, Sara T St James, Kenneth Ulin, Sue S Yom, and Torunn I Yock