The Cancer Institute is a leader in cutting-edge treatments. Using a truly multidisciplinary approach, patients have access to advanced diagnostics, minimally invasive surgical interventions, and personalized genomic and immune-oncologic treatment options. Our team of cancer specialists – many of whom completed fellowships and specialty training at prestigious academic centers – offers comprehensive services for individuals with a cancer diagnosis.

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Submissions from 2018

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Clinical outcomes five years after POEM for treatment of primary esophageal motility disorders., Ezra N Teitelbaum, Christy M Dunst, Kevin M Reavis, Ahmed M Sharata, Marc A Ward, Steven R DeMeester, and Lee L Swanström

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Ovarian Cancer, Krishnansu S Tewari, Richard T. Penson, and Bradley J. Monk

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Randomized phase II trial of bevacizumab plus everolimus versus bevacizumab alone for recurrent or persistent ovarian, fallopian tube or peritoneal carcinoma: An NRG oncology/gynecologic oncology group study., William P Tew, Michael W Sill, Joan L Walker, Angeles Alvarez Secord, Albert J Bonebrake, Jeanne M Schilder, Ashley Stuckey, Laurel Rice, Krishnansu S Tewari, and Carol A Aghajanian

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Tumor mutational burden is a determinant of immune-mediated survival in breast cancer., Alexandra Thomas, Eric D Routh, Ashok Pullikuth, Guangxu Jin, Jing Su, Jeff W Chou, Katherine A Hoadley, Cristin Print, Nick Knowlton, Michael A Black, Sandra Demaria, Ena Wang, Davide Bedognetti, Wendell D Jones, Gaurav A Mehta, Michael L Gatza, Charles M Perou, David B Page, Pierre Triozzi, and Lance D Miller

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Variability in invasive mediastinal staging for lung cancer: A multicenter regional study., Lucas W Thornblade, Douglas E Wood, Michael S Mulligan, Alexander S Farivar, Michal Hubka, Kimberly E Costas, Bahirathan Krishnadasan, and Farhood Farjah

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The Immune Landscape of Cancer., Vésteinn Thorsson, David L Gibbs, Scott D Brown, Denise Wolf, Dante S Bortone, Tai-Hsien Ou Yang, Eduard Porta-Pardo, Galen F Gao, Christopher L Plaisier, James A Eddy, Elad Ziv, Aedin C Culhane, Evan O Paull, I K Ashok Sivakumar, Andrew J Gentles, Raunaq Malhotra, Farshad Farshidfar, Antonio Colaprico, Joel S Parker, Lisle E Mose, Nam Sy Vo, Jianfang Liu, Yuexin Liu, Janet Rader, Varsha Dhankani, Sheila M Reynolds, Reanne Bowlby, Andrea Califano, Andrew D Cherniack, Dimitris Anastassiou, Davide Bedognetti, Arvind Rao, Ken Chen, Alexander Krasnitz, Hai Hu, Tathiane M Malta, Houtan Noushmehr, Chandra Sekhar Pedamallu, Susan Bullman, Akinyemi I Ojesina, Andrew Lamb, Wanding Zhou, Hui Shen, Toni K Choueiri, John N Weinstein, Justin Guinney, Joel Saltz, Robert A Holt, Charles E Rabkin, Alexander J Lazar, Jonathan S Serody, Elizabeth G Demicco, Mary L Disis, Benjamin G Vincent, and Llya Shmulevich

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Mertk is a therapeutic target in combination with radiation to promote adaptive immune tumor responses, Garth Tormoen, Jason R Baird, Gwen Kramer, Shelly Bambina, Marka R Crittenden, and Michael J. Gough

Role of the immunosuppressive microenvironment in immunotherapy., Garth W Tormoen, Marka R Crittenden, and Michael J. Gough

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Galectin - Method for Enhancing Specific Immunotherapies in Cancer Treatment, Peter G. Traber, William L. Redmond, Eliezer Zomer, Anatole Klyosov, and Stephanie N. Linch

Somatic Mutations and Immunotherapy, Eric Tran

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Su1776 - Superior Survival of South and East Asians with Colorectal Carcinoma in the United States, Abhineet Uppal, Ramkishen Narayanan, Shu-Ching Chang, Trevan Fischer, and Melanie Goldfarb

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Can high-volume teams of anesthesiologists and surgeons decrease perioperative costs for pancreatic surgery?, Abhineet Uppal, Brooke Vuong, Ahmed Dehal, Stacey L Stern, Juan Mejia, Roshanthi Weerasinghe, Vandana Kapoor, Evan Ong, Paul D Hansen, and Anton J Bilchik

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Adjuvant chemotherapy for resected earlier stage adenocarcinomas with unfavorable architecture. Should we incorporate histologic findings to the decision tree?, Eric Vallières

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Glatiramer Acetate Enhances Myeloid-Derived Suppressor Cell Function via Recognition of Paired Ig-like Receptor B., William van der Touw, Kyeongah Kang, Yi Luan, Ge Ma, Sunny Mai, Lihui Qin, Guanglin Bian, Ruihua Zhang, Sathish Kumar Mungamuri, Hong-Ming Hu, Cheng Cheng Zhang, Stuart A Aaronson, Marc Feldmann, Wen-Chin Yang, Shu-Hsia Chen, and Ping-Ying Pan

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Autophagosome-based strategy to monitor apparent tumor-specific CD8 T cells in patients with prostate cancer., Rieneke van de Ven, Traci L Hilton, Hong-Ming Hu, Christopher J Dubay, Daniel Haley, Christopher Paustian, Sachin Puri, Walter Urba, Brendan Curti, Sandra Aung, and Bernard A Fox

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Autophagosome-based strategy to monitor apparent tumor-specific CD8 T cells in patients with prostate cancer, Rieneke van de Ven, Traci L. Hilton, Hong-Ming Hu, Christopher J. Dubay, Daniel Haley, Christopher Paustian, Sachin Puri, Walter J. Urba, Brendan D. Curti, Sandra Aung, and Bernard A. Fox

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Variations in cancer care for adolescents and young adults (AYAs) with ductal carcinoma in situ., Amy Voci, Bradley Bandera, Emily Ho, Jihey Lee, Melanie Goldfarb, and Maggie DiNome

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Impact of port site scar on perception of patients with breast cancer: patient-reported outcomes., Amy Voci, David Lee, Emily Ho, Rebecca Crane-Okada, and Maggie DiNome

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Trastuzumab Emtansine for Residual Invasive HER2-Positive Breast Cancer., Gunter von Minckwitz, Chiun-Sheng Huang, Max S Mano, Sibylle Loibl, Eleftherios P Mamounas, Michael Untch, Norman Wolmark, Priya Rastogi, Andreas Schneeweiss, Andres Redondo, Hans H Fischer, William Jacot, Alison Conlin, Claudia Arce-Salinas, Irene L Wapnir, Christian Jackisch, Michael P DiGiovanna, Peter A Fasching, John P Crown, Pia Wülfing, Zhimin Shao, Elena Rota Caremoli, Haiyan Wu, Lisa H Lam, David Tesarowski, Melanie Smitt, Hannah Douthwaite, Stina M Singel, and Charles E Geyer

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What Are the Most Significant Cost and Value Drivers for Pancreatic Resection in an Integrated Healthcare System?, Brooke Vuong, Ahmed N Dehal, Abhineet Uppal, Stacey L Stern, Juan Mejia, Roshanthi Weerasinghe, Vandana Kapoor, Evan Ong, Paul D Hansen, and Anton J Bilchik

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Isolation of Breast cancer CTCs with multitargeted buoyant immunomicrobubbles., Guankui Wang, Halli Benasutti, Jessica F Jones, Guixin Shi, Michael Benchimol, Sandeep Pingle, Santosh Kesari, Yasan Yeh, Li-En Hsieh, Yu-Tsueng Liu, Anthony Elias, and Dmitri Simberg

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KDM6B counteracts EZH2-mediated suppression of IGFBP5 to confer resistance to PI3K/AKT inhibitor treatment in breast cancer., Wenyu Wang, Keng Gat Lim, Min Feng, Yi Bao, Puay Leng Lee, Cai Yu, Yufeng Chen, Hao Zhang, Diego M Marzese, Dave S B Hoon, and Qiang Yu

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Impact on Oncology Practices of Including Drug Costs in Bundled Payments., Jeffery C Ward, Laura A Levit, Ray D Page, John E Hennessy, John V Cox, Deborah Y Kamin, Suanna S Bruinooge, Ya-Chen Tina Shih, and Blase N Polite

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Factors predicting attrition in community-based healthcare network lung cancer screening programs The International Association for the Study of Lung Cancer 19th World Conference on Lung Canc, Roshanthi Weerasignhe, Candice L. Wilshire, and See all authors in comments

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Tumor cell-released autophagosomes (TRAPs) promote immunosuppression through induction of M2-like macrophages with increased expression of PD-L1., Zhi-Fa Wen, Hongxiang Liu, Rong Gao, Meng Zhou, Jie Ma, Yue Zhang, Jinjin Zhao, Yongqiang Chen, Tianyu Zhang, Fang Huang, Ning Pan, Jinping Zhang, Bernard A Fox, Hong-Ming Hu, and Li-Xin Wang

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Moving Beyond Limited and Extensive Staging of Small Cell Lung Cancer., Howard Jack West

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Redefining the Value Proposition of Precision Oncology: Can We Integrate Genomic Testing Without Overselling It?, Howard Jack West

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Paired Phase II Studies of Erlotinib/Bevacizumab for Advanced Bronchioloalveolar Carcinoma or Never Smokers With Advanced Non-Small-cell Lung Cancer: SWOG S0635 and S0636 Trials., Howard L West, James Moon, Antoinette J Wozniak, Philip Mack, Fred R Hirsch, Martin J Bury, Myron Kwong, Dorothy D Nguyen, Dennis F Moore, Jieling Miao, Mary Redman, Karen Kelly, and David R Gandara

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Multicenter review suggests tunnelled pleural catheter use in antineoplastic therapy-related immun, Candice L. Wilshire

Multicenter review of thymectomy indicated for myasthenia gravis favors a left-sided approach and lower severity class, Candice L. Wilshire, CC Fuller, AF Ghanim, RJ Cerfolio, MW Onaitis, V Joshi, DA Wigle, RW Aye, AS Farivar, E Vallières, and BE Louie

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Tunneled pleural catheter use for pleural palliation does not increase infection rate in patients with treatment-related immunosuppression., Candice L. Wilshire, Christopher R Gilbert, Brian E Louie, Ralph W Aye, Alexander S Farivar, Eric Vallières, and Jed A Gorden

Multicenter review of tunnelled pleural catheter implementation and use in patients with malignant pleural effusions, Candice L. Wilshire, CR Gilbert, JA Akulian, R Asciak, B Bevill, KR Davidson, A Delgado, HJ Lee, JE Lewis, F Maldonado, NJ Pastis, NM Rahman, CB Reddy, and See additional authors in comments

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Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: American Society of Clinical Oncology/College of American Pathologists Clinical Practice Guideline Focused Update., Antonio C Wolff, M Elizabeth Hale Hammond, Kimberly H Allison, Brittany E Harvey, Pamela B Mangu, John M S Bartlett, Michael Bilous, Ian O Ellis, Patrick Fitzgibbons, Wedad Hanna, Robert B Jenkins, Michael F Press, Patricia A Spears, Gail H Vance, Giuseppe Viale, Lisa M McShane, and Mitchell Dowsett

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Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: American Society of Clinical Oncology/College of American Pathologists Clinical Practice Guideline Focused Update., Antonio C Wolff, M Elizabeth Hale Hammond, Kimberly H Allison, Brittany E Harvey, Pamela B Mangu, John M S Bartlett, Michael Bilous, Ian O Ellis, Patrick Fitzgibbons, Wedad Hanna, Robert B Jenkins, Michael F Press, Patricia A Spears, Gail H Vance, Giuseppe Viale, Lisa M McShane, and Mitchell Dowsett

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Rational design for cervical cancer therapeutics: cellular and non-cellular based strategies on the horizon for recurrent, metastatic or refractory cervical cancer., Juliet E Wolford and Krishnansu S Tewari

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ALT-803, an IL-15 superagonist, in combination with nivolumab in patients with metastatic non-small cell lung cancer: a non-randomised, open-label, phase 1b trial., John M Wrangle, Vamsidhar Velcheti, Manish R Patel, Elizabeth Garrett-Mayer, Elizabeth G Hill, James G Ravenel, Jeffrey S Miller, Mohammad Farhad, Kate Anderton, Kathryn Lindsey, Michele Taffaro-Neskey, Carol Sherman, Samantha Suriano, Marzena Swiderska-Syn, Amy Sion, Joni Harris, Andie R Edwards, Julie A Rytlewski, Catherine M Sanders, Erik C Yusko, Mark D Robinson, Carsten Krieg, William L Redmond, Jack O Egan, Peter R Rhode, Emily K Jeng, Amy D Rock, Hing C Wong, and Mark P Rubinstein

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Recurrent tumor-specific regulation of alternative polyadenylation of cancer-related genes., Zhuyi Xue, René L Warren, Ewan A Gibb, Daniel MacMillan, Johnathan Wong, Readman Chiu, S Austin Hammond, Chen Yang, Ka Ming Nip, Catherine A Ennis, Abigail Hahn, Sheila Reynolds, and Inanc Birol

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Whole-Mount Adult Ear Skin Imaging Reveals Defective Neuro-Vascular Branching Morphogenesis in Obese and Type 2 Diabetic Mouse Models., Tomoko Yamazaki, Wenling Li, Ling Yang, Ping Li, Haiming Cao, Sei-Ichiro Motegi, Mark C Udey, Elise Bernhard, Takahisa Nakamura, and Yoh-Suke Mukouyama

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Tissue Specific Origin, Development, and Pathological Perspectives of Pericytes., Tomoko Yamazaki and Yoh-Suke Mukouyama

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Molecular subgroups and B7-H4 expression levels predict responses to dendritic cell vaccines in glioblastoma: an exploratory randomized phase II clinical trial., Yu Yao, Feifei Luo, Chao Tang, Dikang Chen, Zhiyong Qin, Wei Hua, Ming Xu, Ping Zhong, Shuangquan Yu, Di Chen, Xiaojie Ding, Yi Zhang, Xiujuan Zheng, Jiao Yang, Jiawen Qian, Yuting Deng, Dave S B Hoon, Jian Hu, Yiwei Chu, and Liangfu Zhou

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Enhanced detection of neoantigen-reactive T cells targeting unique and shared oncogenes for personalized cancer immunotherapy., Rami Yossef, Eric Tran, Drew C Deniger, Alena Gros, Anna Pasetto, Maria R Parkhurst, Jared J Gartner, Todd D Prickett, Gal Cafri, Paul F Robbins, and Steven A Rosenberg

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P16-positive cystic squamous cell carcinoma in midline neck: metastasis from oropharynx or primary carcinoma arising from thyroglossal duct cyst?, Songlin Zhang, Hong D Xiao, Zhenjian Cai, Michael Covinsky, Karan Saluja, Maria O Patino, Xinmin Liu, and Hui Zhu

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Vx3-Functionalized Alumina Nanoparticles Assisted Enrichment of Ubiquitinated Proteins from Cancer Cells for Enhanced Cancer Immunotherapy., Jinjin Zhao, Ning Pan, Fang Huang, Mohanad Aldarouish, Zhifa Wen, Rong Gao, Yuye Zhang, Hong-Ming Hu, Yanfei Shen, and Li-Xin Wang

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Author Correction: Extracting Intercellular Signaling Network of Cancer Tissues using Ligand-Receptor Expression Patterns from Whole-tumor and Single-cell Transcriptomes., Joseph X Zhou, Roberto Taramelli, Edoardo Pedrini, Theo Knijnenburg, and Sui Huang

Submissions from 2017

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New Cancer Immunotherapy Agents in Development: a report from an associated program of the 31, Prasad S Adusumilli, Edward Cha, Mark Cornfeld, Thomas Davis, Adi Diab, Thomas W Dubensky, Elizabeth Evans, Jane L Grogan, Bryan A Irving, Rom Leidner, Shane A Olwill, Patrick Soon-Shiong, Frederic Triebel, David Tuck, Adrian Bot, Roger D Dansey, Charles G Drake, Gordon J Freeman, Ramy Ibrahim, Salil Patel, and Daniel S Chen

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NADPH oxidase 5 (NOX5)-induced reactive oxygen signaling modulates normoxic HIF-1α and p27, Smitha Antony, Guojian Jiang, Yongzhong Wu, Jennifer L Meitzler, Hala R Makhlouf, Diana C Haines, Donna Butcher, Dave S B Hoon, Jiuping Ji, Yiping Zhang, Agnes Juhasz, Jiamo Lu, Han Liu, Iris Dahan, Mariam Konate, Krishnendu K Roy, and James H Doroshow

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Phase 1b trial of proteasome inhibitor carfilzomib with irinotecan in lung cancer and other irinotecan-sensitive malignancies that have progressed on prior therapy (Onyx IST reference number: CAR-IST-553)., Susanne M Arnold, Kari Chansky, Markos Leggas, Michael A Thompson, John L Villano, John Hamm, Rachel E Sanborn, Glen J Weiss, Gurkamal Chatta, and Maria Q Baggstrom

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Surgical Navigation: A Systematic Review of Indications, Treatments, and Outcomes in Oral and Maxillofacial Surgery., Iman Azarmehr, Kasper Stokbro, R Bryan Bell, and Torben Thygesen

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Emergency Presentations of Colorectal Cancer., Canaan Baer, Raman Menon, Sarah Bastawrous, and Amir Bastawrous

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STING expression and response to treatment with STING ligands in premalignant and malignant disease., Jason R Baird, Zipei Feng, Hong D Xiao, David Friedman, Ben Cottam, Bernard A Fox, Gwen Kramer, Rom S Leidner, Richard Bryan Bell, Kristina H Young, Marka R Crittenden, and Michael J Gough

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Microsurgical Endoscope-Assisted Gravity-Aided Transfalcine Approach for Contralateral Metastatic Deep Medial Cortical Tumors., Garni Barkhoudarian, Daniel Farahmand, Robert G Louis, Erol Oksuz, Danjuma Sale, Pablo Villanueva, and Daniel F Kelly

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Impact of ibrutinib dose adherence on therapeutic efficacy in patients with previously treated CLL/SLL., Paul M Barr, Jennifer R Brown, Peter Hillmen, Susan O'Brien, Jacqueline C Barrientos, Nishitha M Reddy, Steven Coutre, Stephen P Mulligan, Ulrich Jaeger, Richard R Furman, Florence Cymbalista, Marco Montillo, Claire Dearden, Tadeusz Robak, Carol Moreno, John M Pagel, Jan A Burger, Samuel Suzuki, Juthamas Sukbuntherng, George Cole, Danelle F James, and John C Byrd

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Agenda for Translating Physical Activity, Nutrition, and Weight Management Interventions for Cancer Survivors into Clinical and Community Practice., Karen Basen-Engquist, Catherine M Alfano, Melissa Maitin-Shepard, Cynthia A Thomson, Kathryn H Schmitz, Bernardine M Pinto, Kevin Stein, David S Zucker, Karen L Syrjala, Elizabeth Fallon, Colleen Doyle, and Wendy Demark-Wahnefried

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Immunotherapy of head and neck cancer: Emerging clinical trials from a National Cancer Institute Head and Neck Cancer Steering Committee Planning Meeting., Julie E Bauman, Ezra Cohen, Robert L Ferris, David J Adelstein, David M Brizel, John A Ridge, Brian O'Sullivan, Barbara A Burtness, Lisa H Butterfield, William E Carson, Mary L Disis, Bernard A Fox, Thomas F Gajewski, Maura L Gillison, James W Hodge, Quynh-Thu Le, David Raben, Scott E Strome, Jean Lynn, and Shakun Malik

Oral, Head and Neck Oncology and Reconstructive Surgery, R. Bryan Bell, Peter E. Andersen, and Rui P. Fernandes

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Relationships matter in oral cancer: will single-stain immunohistochemistry become irrelevant in the age of multispectral imaging?, R Bryan Bell and Bernard A Fox

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Erratum to 'Cytoreductive surgery for head and neck squamous cell carcinoma in the new age of immunotherapy' [Oral Oncol. 61 (2016) 166-176]., R Bryan Bell, Michael J Gough, Steven K Seung, Zeljka Jutric, Andrew D Weinberg, Bernard A Fox, Marka R Crittenden, Rom S Leidner, and Brendan Curti

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Head and neck surgeons at the vanguard of immunotherapy., Richard Bryan Bell

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Immunoprofiling as a predictor of patient's response to cancer therapy-promises and challenges., Daniel Bethmann, Zipei Feng, and Bernard A Fox

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IGF2 mRNA binding protein 3 (IMP3) promotes glioma cell migration by enhancing the translation of RELA/p65., Shruti Bhargava, Abhirami Visvanathan, Vikas Patil, Anuj Kumar, Santosh Kesari, Saumitra Das, Alangar S Hegde, Arimappamagan Arivazhagan, Vani Santosh, and Kumaravel Somasundaram

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Precision Oncology: Between Vaguely Right and Precisely Wrong., Amy Brock and Sui Huang

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Robot-Assisted Total Thymectomy: How I Teach It., Lisa M Brown and Brian Louie

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Photography in Telemedicine: Improving Diagnosis of Chronic Graft-Versus-Host Disease., Brianna Busby, Shannon Campbell, Rachel Cole, Charisse DeVries, Kamille Dobbins, Mary Beth Trimble, and Mihkaila Wickline

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Genome-wide chromatin accessibility, DNA methylation and gene expression analysis of histone deacetylase inhibition in triple-negative breast cancer., Matias A Bustos, Matthew P Salomon, Nellie Nelson, Sandy C Hsu, Maggie L DiNome, Dave S B Hoon, and Diego M Marzese

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MiR-200a Regulates CDK4/6 Inhibitor Effect by Targeting CDK6 in Metastatic Melanoma., Matias Bustos, Shigeshi Ono, Diego M Marzese, Takashi Oyama, Yuuki Iida, Garrett Cheung, Nellie Nelson, Sandy C Hsu, Qiang Yu, and Dave S B Hoon

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OA01. 03 Attrition Rate in Community-Based Lung Cancer Screening: One and Done: Topic: Pulmonology, AS Carlson, Candice L. Wilshire, Joelle T Fathi, JR Rayburn, Christopher R Gilbert, SC Blanshan, Brian Louie, Ralph W Aye, Alexander S Farivar, Eric Vallieres, and Jed A Gorden

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Attrition rate in community-based lung cancer screening: one and done, AS Carlson, Candice L. Wilshire, JT Fathi, CR Gilbert, SC Blanshan, BE Louie, RW Aye, AS Farivar, E Vallières, and JA Gorden

Attrition rate in community-based lung cancer screening: one and done The International Association for the Study of Lung Cancer 18th World Conference on Lung Cancer Yokohama, Japan, AS Carlson, Candice L. Wilshire, and See all authors in comments

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External Validation of a Prognostic Model of Survival for Resected Typical Bronchial Carcinoids., Maria Cattoni, Eric Vallieres, Lisa M Brown, Amir A Sarkeshik, Stefano Margaritora, Alessandra Siciliani, Andrea Imperatori, Nicola Rotolo, Farhood Farjah, Grace Wandell, Kimberly E Costas, Catherine Mann, Michal Hubka, Stephen Kaplan, Alexander S Farivar, Ralph W Aye, and Brian Louie

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The IASLC Lung Cancer Staging Project: External Validation of the Revision of the TNM Stage Groupings in the Eighth Edition of the TNM Classification of Lung Cancer., Kari Chansky, Frank C Detterbeck, Andrew G Nicholson, Valerie W Rusch, Eric Vallières, Patti Groome, Catherine Kennedy, Mark Krasnik, Michael Peake, Lynn Shemanski, Vanessa Bolejack, John J Crowley, Hisao Asamura, and Ramón Rami-Porta

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ATR Mutations Promote the Growth of Melanoma Tumors by Modulating the Immune Microenvironment., Chi-Fen Chen, Rolando Ruiz-Vega, Priya Vasudeva, Francisco Espitia, Tatiana B Krasieva, Sebastien de Feraudy, Bruce J Tromberg, Sharon Huang, Chad P Garner, Jie Wu, Dave S B Hoon, and Anand K Ganesan

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Cancer Rehabilitation: An Overview of Current Need, Delivery Models, and Levels of Care., Andrea L Cheville, Karen Mustian, Kerri Winters-Stone, David S Zucker, Gail L Gamble, and Catherine M Alfano

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National Estimates of Genetic Testing in Women With a History of Breast or Ovarian Cancer., Christopher P Childers, Kimberly K Childers, Melinda Maggard-Gibbons, and James Macinko

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POINT AND COUNTERPOINT, Geoffrey Lowell Chupp, Valerie G. Press, Andrea Gershon, Denitza P. Blagev, Caroline Mitchell, Rod Lawson, Wesley H. Self, Matthew W. Semler, Todd W. Rice, Alfin G. Vicencio, Joseph Piccione, Srinath Adusumalli, Bram Geller, Jay Giri, Jed A Gorden, Candice L. Wilshire, and Christopher R Gilbert

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Impact of Sequencing Targeted Therapies With High-dose Interleukin-2 Immunotherapy: An Analysis of Outcome and Survival of Patients With Metastatic Renal Cell Carcinoma From an On-going Observational IL-2 Clinical Trial: PROCLAIM, Joseph I Clark, Michael K K Wong, Howard L Kaufman, Gregory A Daniels, Michael A Morse, David F McDermott, Sanjiv S Agarwala, Lionel D Lewis, John H Stewart, Ulka Vaishampayan, Brendan Curti, René Gonzalez, Jose Lutzky, Venkatesh Rudraptna, Lee D Cranmer, Joanne M Jeter, Ralph J Hauke, Gerald Miletello, Mohammed M Milhem, Asim Amin, John M Richart, Mayer Fishman, Sigrun Hallmeyer, Sapna P Patel, Peter Van Veldhuizen, Neeraj Agarwal, Bret Taback, Jonathan S Treisman, Marc S Ernstoff, Jessica C Perritt, Hong Hua, Tharak B Rao, Janice P Dutcher, and Sandra Aung

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Results of a phase I-II study of fenretinide and rituximab for patients with indolent B-cell lymphoma and mantle cell lymphoma., Andrew J Cowan, Phillip A Stevenson, Ted A Gooley, Shani L Frayo, George R Oliveira, Stephen D Smith, Damian J Green, Jennifer E Roden, John M Pagel, Brent L Wood, Oliver W Press, and Ajay K Gopal

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Chemotherapy Safe Handling: Limiting Nursing Exposure With a Hazardous Drug Control Program., Rachael Crickman

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Improved survival and tumor control with Interleukin-2 is associated with the development of immune-related adverse events: data from the PROCLAIM, Brendan Curti, Gregory A Daniels, David F McDermott, Joseph I Clark, Howard L Kaufman, Theodore F Logan, Jatinder Singh, Meenu Kaur, Theresa L Luna, Nancy Gregory, Michael A Morse, Michael K K Wong, and Janice P Dutcher

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Phase I First-in-Human Study of Venetoclax in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma., Matthew S Davids, Andrew W Roberts, John F Seymour, John M Pagel, Brad S Kahl, William G Wierda, Soham Puvvada, Thomas J Kipps, Mary Ann Anderson, Ahmed Hamed Salem, Martin Dunbar, Ming Zhu, Franklin Peale, Jeremy A Ross, Lori Gressick, Monali Desai, Su Young Kim, Maria Verdugo, Rod A Humerickhouse, Gary B Gordon, and John F Gerecitano

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Effect of alkylaminophenols on growth inhibition and apoptosis of bone cancer cells., Phuong Doan, Tien Nguyen, Olli Yli-Harja, Nuno R Candeias, and Meenakshisundaram Kandhavelu

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Nivolumab in patients with advanced hepatocellular carcinoma (CheckMate 040): an open-label, non-comparative, phase 1/2 dose escalation and expansion trial., Anthony B El-Khoueiry, Bruno Sangro, Thomas Yau, Todd S Crocenzi, Masatoshi Kudo, Chiun Hsu, Tae-You Kim, Su-Pin Choo, Jörg Trojan, Theodore H Welling, Tim Meyer, Yoon-Koo Kang, Winnie Yeo, Akhil Chopra, Jeffrey Anderson, Christine Dela Cruz, Lixin Lang, Jaclyn Neely, Hao Tang, Homa B Dastani, and Ignacio Melero

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Pathologists' diagnosis of invasive melanoma and melanocytic proliferations: observer accuracy and reproducibility study., Joann G Elmore, Raymond L Barnhill, David E Elder, Gary M Longton, Margaret S Pepe, Lisa M Reisch, Patricia A Carney, Linda J Titus, Heidi D Nelson, Tracy Onega, Anna N A Tosteson, Martin A Weinstock, Stevan R Knezevich, and Michael W Piepkorn

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A Randomized Study Comparing Digital Imaging to Traditional Glass Slide Microscopy for Breast Biopsy and Cancer Diagnosis., Joann G Elmore, Gary M Longton, Margaret S Pepe, Patricia A Carney, Heidi D Nelson, Kimberly H Allison, Berta M Geller, Tracy Onega, Anna N A Tosteson, Ezgi Mercan, Linda G Shapiro, Tad T Brunyé, Thomas R Morgan, and Donald L Weaver

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Cancer immunotherapy: Opportunities and challenges in the rapidly evolving clinical landscape., Leisha A Emens, Paolo A Ascierto, Phillip K Darcy, Sandra Demaria, Alexander M M Eggermont, William L. Redmond, Barbara Seliger, and Francesco M Marincola

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Hypomethylation of CNTFRα is associated with proliferation and poor prognosis in lower grade gliomas., Kun Fan, Xiaowen Wang, Jingwen Zhang, Romela Irene Ramos, Haibo Zhang, Chunjie Li, Dan Ye, Jiansheng Kang, Diego M Marzese, Dave S B Hoon, and Wei Hua

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Long-Term Survival after Complete Surgical Resection and Adjuvant Immunotherapy for Distant Melanoma Metastases., Mark Faries, Nicola Mozzillo, Mohammed Kashani-Sabet, John F Thompson, Mark C Kelley, Ronald C DeConti, Jeffrey E Lee, James F Huth, Jeffrey Wagner, Angus Dalgleish, Daniel Pertschuk, Christopher Nardo, Stacey Stern, Robert Elashoff, Guy Gammon, and Donald L Morton

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Completion Dissection or Observation for Sentinel-Node Metastasis in Melanoma., Mark Faries, John F Thompson, Alistair J Cochran, Robert H Andtbacka, Nicola Mozzillo, Jonathan S Zager, Tiina Jahkola, Tawnya L Bowles, Alessandro Testori, Peter D Beitsch, Harald J Hoekstra, Marc Moncrieff, Christian Ingvar, Michel W J M Wouters, Michael S Sabel, Edward A Levine, Doreen Agnese, Michael Henderson, Reinhard Dummer, Carlo R Rossi, Rogerio I Neves, Steven D Trocha, Frances Wright, David R Byrd, Maurice Matter, Eddy Hsueh, Alastair MacKenzie-Ross, Douglas B Johnson, Patrick Terheyden, Adam C Berger, Tara L Huston, Jeffrey D Wayne, B Mark Smithers, Heather B Neuman, Schlomo Schneebaum, Jeffrey E Gershenwald, Charlotte E Ariyan, Darius C Desai, Lisa Jacobs, Kelly M McMasters, Anja Gesierich, Peter Hersey, Steven D Bines, John M Kane, Richard J Barth, Gregory McKinnon, Jeffrey M Farma, Erwin Schultz, Sergi Vidal-Sicart, Richard A Hoefer, James M Lewis, Randall Scheri, Mark C Kelley, Omgo E Nieweg, R Dirk Noyes, Dave S B Hoon, He-Jing Wang, David A Elashoff, and Robert M Elashoff

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C30 LUNG CANCER SCREENING: WHO, WHY, WHERE, AND HOW MUCH: Integrating Smoking Cessation Counseling And Treatment In A Lung Cancer Screening Program: An Effective Approach To Long-Term Smoking Cessation Success, Joelle T Fathi, SC Blanshan, AK Wilson, Candice L. Wilshire, Christopher R Gilbert, Ralph W Aye, Alexander S Farivar, Brian Louie, Eric Vallieres, and Jed A Gorden

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Electronic medical record inaccuracies: a multi-center analysis of the challenges for population-based lung cancer screening The American Thoracic Society Washington DC, JT Fathi, Candice L. Wilshire, and See all authors in comments

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Integrating smoking cessation counselling and treatment in a lung cancer screening program: an effective approach to long-term smoking cessation success The American Thoracic Society Wash, AF Feczko, Candice L. Wilshire, and See all authors in comments

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Multiparametric immune profiling in HPV- oral squamous cell cancer., Zipei Feng, Daniel Bethmann, Matthias Kappler, Carmen Ballesteros-Merino, Alexander Eckert, R Bryan Bell, Allen Cheng, Tuan Bui, Rom Leidner, Walter Urba, Kent Johnson, Clifford Hoyt, Carlo Bifulco, Juergen Bukur, Claudia Wickenhauser, Barbara Seliger, and Bernard A Fox

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Descriptive analysis of unplanned readmission and reoperation rates after intradural spinal tumor resection., Christian Fisahn, Felipe H Sanders, Marc Moisi, Jeni Page, Peter C Oakes, Mary Wingerson, Joe Dettori, R Shane Tubbs, Parthasarathi Chamiraju, Peter Nora, David Newell, Johnny Delashaw, Rod J Oskouian, and Jens R Chapman

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Human cytomegalovirus-mediated immunomodulation: Effects on glioblastoma progression., Haidn Foster, Ilya V Ulasov, and Charles Cobbs

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Frontline brentuximab vedotin in combination with dacarbazine or bendamustine in patients aged ≥60 years with HL., Jonathan W Friedberg, Andres Forero-Torres, Rodolfo E Bordoni, Vivian J M Cline, Dipti Patel Donnelly, Patrick J Flynn, Gregg Olsen, Robert Chen, Abraham Fong, Yinghui Wang, and Christopher A Yasenchak

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Minority and economically disadvantaged high-risk populations are underrepresented in both centralized and decentralized lung cancer screening models, CC Fuller, Candice L. Wilshire, and M Bretta

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A48 COPD: ISSUES IN HEALTH CARE DELIVERY: Electronic Medical Record Inaccuracies: A Multi-Center Analysis Of The Challenges For Population-Based Lung Cancer Screening, CC Fuller, Candice L. Wilshire, Christopher R Gilbert, Joelle T Fathi, JR Handy, KE Costas, Brian Louie, Ralph W Aye, Alexander S Farivar, Eric Vallieres, and Jed A Gorden

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D20 LUNG CANCER SCREENING: MOVING FROM POPULATION TO PERSON: Minority And Economically Disadvantaged High-Risk Populations Are Underrepresented In Both Centralized And Decentralized Lung Cancer Screening Models, CC Fuller, Candice L. Wilshire, BM McCall, Christopher R Gilbert, Joelle T Fathi, JR Handy, KE Costas, Brian Louie, Ralph W Aye, Alexander S Farivar, Eric Vallieres, and Jed A Gorden

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Sex-Specific Differences in Colon Cancer when Quality Measures Are Adhered to: Results from International, Prospective, Multicenter Clinical Trials., Shrawan G Gaitonde, Aviram Nissan, Mladjan Protić, Alexander Stojadinovic, Zev A Wainberg, David C Chen, and Anton J Bilchik

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Efficacy and Safety of Pembrolizumab in Patients Enrolled in KEYNOTE-030 in the United States: An Expanded Access Program., Tara C Gangadhar, Wen-Jen Hwu, Michael A Postow, Omid Hamid, Adil Daud, Roxana Dronca, Richard Joseph, Steven J O'Day, F S Hodi, Anna C Pavlick, Harriet Kluger, Romina P Oxborough, Aiming Yang, Mihaela Gazdoiu, Debra A Kush, Scot Ebbinghaus, and April K S Salama

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Genetic and Genomic Characterization of 462 Melanoma Patient-Derived Xenografts, Tumor Biopsies, and Cell Lines., Bradley Garman, Ioannis N Anastopoulos, Clemens Krepler, Patricia Brafford, Katrin Sproesser, Yuchao Jiang, Bradley Wubbenhorst, Ravi Amaravadi, Joseph Bennett, Marilda Beqiri, David Elder, Keith T Flaherty, Dennie T Frederick, Tara C Gangadhar, Michael Guarino, Dave S B Hoon, Giorgos Karakousis, Qin Liu, Nandita Mitra, Nicholas J Petrelli, Lynn Schuchter, Batool Shannan, Carol L Shields, Jennifer Wargo, Brandon Wenz, Melissa A Wilson, Min Xiao, Wei Xu, Xaiowei Xu, Xiangfan Yin, Nancy R Zhang, Michael A Davies, Meenhard Herlyn, and Katherine L Nathanson