The Digestive Health Institute is a network of highly trained doctors and surgeons who treat disorders of the gastrointestinal (GI) tract, as well as the liver, gallbladder and pancreas. As it becomes increasingly complex to treat digestive diseases and GI cancer, optimizing care relies more on the close collaboration of experts from across disciplines.

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Submissions from 2021

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DUOX2 variants associate with preclinical disturbances in microbiota-immune homeostasis and increased inflammatory bowel disease risk., Helmut Grasberger, Andrew T Magis, Elisa Sheng, Matthew P Conomos, Min Zhang, Lea S Garzotto, Guoqing Hou, Shrinivas Bishu, Hiroko Nagao-Kitamoto, Mohamad El-Zataari, Sho Kitamoto, Nobuhiko Kamada, Ryan Stidham, Yasutada Akiba, Jonathan Kaunitz, Yael Haberman, Subra Kugathasan, Lee A Denson, Gilbert S Omenn, and John Y Kao

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Germinal center reactions in tertiary lymphoid structures associate with neoantigen burden, humoral immunity and long-term survivorship in pancreatic cancer., Andrew J Gunderson, Venkatesh Rajamanickam, Cynthia Bui, Brady Bernard, Joanna Pucilowska, Carmen Ballesteros-Merino, Mark Schmidt, Kayla McCarty, Michaela Philips, Brian D. Piening, Christopher Dubay, Terry R Medler, Phillipa Newell, Paul D Hansen, Eric Tran, Ephraim Tang, Carlo Bifulco, Marka R Crittenden, Michael J. Gough, and Kristina H Young

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Robotic surgical management of sigmoid colon cancer in pregnancy: A case series., Edward R Hagen, Leigh Gerson, Laila Rashidi, and Amir Bastawrous

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Hepatic Plexus Nerve Block for Microwave Ablation of Hepatic Tumors., Frank Hao, Navid Eghbalieh, Alexandra So, and Edward Wolfgang Lee

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Congenital Myenteric Hypoganglionosis., Raj P Kapur, Andrew M Bellizzi, Steffan Bond, Haiying Chen, Jeong S Han, Robin D LeGallo, Craig Midgen, Alysa A Poulin, Naseem Uddin, Mikako Warren, José E Velázquez Vega, and Craig W Zuppan

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Case series and review of Ayurvedic medication induced liver injury., Christopher M Karousatos, Justin K Lee, David R Braxton, and Tse-Ling Fong

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Diagnostic Concordance of Cytology and Histology in Samples Obtained via Endoscopic Ultrasound-Guided Fine-Needle Biopsy (EUS-FNB)., Tara Keihanian, Liege Diaz, Liza Plafsky, Uday Shergill, Jinendra Satiya, Rtika Abraham, Monica Garcia-Buitrago, James H Tabibian, and Mohit Girotra

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Response: Incorporating Telemedicine in Gastroenterology practice and training., Tara Keihanian and Mohit Girotra

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Evaluation of MyFitnessPal’s Recommended Protein Intake Compared to The United States Recommended Dietary Allowances, Matthew C. Kokos, Christina Dobrowski, Aarika Merrill, Shaekira L. Niehuser, Teresa Bigand, and Ross J. Bindler

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Genomic and functional characterization of a mucosal symbiont involved in early-stage colorectal cancer., Melissa C Kordahi, Ian B Stanaway, Marion Avril, Denise Chac, Marie-Pierre Blanc, Benjamin Ross, Christian Diener, Sumita Jain, Paul McCleary, Ana Parker, Vincent Friedman, Jennifer Huang, Wynn Burke, Sean M Gibbons, Amy D Willis, Richard P Darveau, William M Grady, Cynthia W Ko, and R William DePaolo

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Changes in Carcinoid Syndrome Symptoms Among Patients Receiving Telotristat Ethyl in US Clinical Practice: Findings from the TELEPRO-II Real-World Study., Matthew H Kulke, Hagen F Kennecke, Kris Murali, and Vijay N Joish

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Changes in Hemoglobin Levels in Patients with Hiatal Hernia and Anemia Demonstrates a Durable Resolution When Surgery Utilized, Anne Sophie Laliberte, John A. Brandabur, Shu-Ching Chang, Peter U. Balik, Anee Sophia Jackson, Adam J Bograd, Ralph W Aye, Alexander S Farivar, and Brian Louie

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Coinfection of, Samragnyi Madala, Kira MacDougall, Balarama Krishna Surapaneni, Robin Park, Mohit Girotra, and Anup Kasi

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Trifluridine/tipiracil in patients with metastatic gastroesophageal junction cancer: a subgroup analysis from the phase 3 TAGS study., Wasat Mansoor, Hendrik-Tobias Arkenau, Maria Alsina, Kohei Shitara, Peter Thuss-Patience, Sinead Cuffe, Mikhail Dvorkin, David Park, Takayuki Ando, Marc Van Den Eynde, Giordano D Beretta, Alberto Zaniboni, Toshihiko Doi, Josep Tabernero, David H Ilson, Lukas Makris, Karim A Benhadji, and Eric Van Cutsem

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Large polyps: Pearls for the referring and receiving endoscopist., Eric Markarian, Brian M Fung, Mohit Girotra, and James H Tabibian

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POEM: clinical outcomes beyond 5 years., Sarah C McKay, Christy M Dunst, Ahmed M Sharata, Reid Fletcher, Kevin M Reavis, Daniel Davila Bradley, Steven R DeMeester, Dolores Müller, Brett Parker, and Lee L Swanström

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Suspecting and Diagnosing the Patient with Spondyloarthritis and What to Expect from Therapy., Philip J Mease

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Outcomes of colostomy takedown following Hartmann's procedure: successful restoration of continuity comes with a high risk of morbidity., Kasim L Mirza, Carey J Wickham, Erik R Noren, Grace S Hwang, Glenn T Ault, Adrian E Ortega, Mehraneh D Jafari, and Kyle G Cologne

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High Resolution Manometry in a Functioning Fundoplication - Establishing a Standard Profile: Retrospective Chart Review., Dolores T Müller, Brett Parker, Reid Fletcher, Ahmed M Sharata, Daniel Davila Bradley, Steven R DeMeester, Kevin M Reavis, Lee L Swanstrom, and Christy M Dunst

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Regulation of MRE11A by UBQLN4 leads to cisplatin resistance in patients with esophageal squamous cell carcinoma., Tomohiro Murakami, Yoshiaki Shoji, Tomohiko Nishi, Shu-Ching Chang, Ron D Jachimowicz, Sojun Hoshimoto, Shigeshi Ono, Yosef Shiloh, Hiroya Takeuchi, Yuko Kitagawa, Dave Hoon, and Matias Bustos

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Collagenous Gastritis in Primary Selective IgM Deficiency: Transition to EBV+ Gastric Adenocarcinoma., Tejal Narsai, Houfen Su, David Braxton, and Sudhir Gupta

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Eating Disorders: Identification and Management in General Medical and Psychiatric Settings., Rebecca A Owens, Evelyn Attia, Joyce J Fitzpatrick, Kathryn Phillips, and Stephanie Nolan

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Educational intervention to improve quality of care in Barrett's esophagus: the AQUIRE randomized controlled trial., Sravanthi Parasa, Michael B Wallace, Sachin Srinivasan, Suneha Sundaram, Kevin F Kennedy, Lucas J Williams, and Prateek Sharma

Integrated Personal Omics Profiling for Obesity, Brian D. Piening

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Decreased Antibody Responses to Ad26.COV2.S Relative to SARS-CoV-2 mRNA Vaccines in Patients with Inflammatory Bowel Disease., Valeriya Pozdnyakova, Gregory J Botwin, Kimia Sobhani, John Prostko, Jonathan Braun, Dermot P B McGovern, Gil Y Melmed, CORALE-IBD study group, Keren Appel, Andrea Banty, Edward Feldman, Christina Ha, Rashmi Kumar, Susie Lee, Shervin Rabizadeh, Theodore Stein, Gaurav Syal, Stephan Targan, Eric Vasiliauskas, David Ziring, Philip Debbas, Melissa Hampton, Emebet Mengesha, James L Stewart, Edwin C Frias, Susan Cheng, Joseph Ebinger, Jane Figuereido, Brigid Boland, Aline Charabaty, Michael Chiorean, Erica Cohen, Ann Flynn, John Valentine, David Fudman, Arash Horizon, Jason Hou, Caroline Hwang, Mark Lazarev, Donald Lum, Rebecca Fausel, Swapna Reddy, Mark Mattar, Mark Metwally, Arthur Ostrov, Nimisha Parekh, Laura Raffals, Sarah Sheibani, Corey Siegel, Douglas Wolf, and Ziad Younes

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Operating costs, fiscal impact, value analysis and guidance for the routine use of robotic technology in abdominal surgical procedures., Philippe J Quilici, Harry Wolberg, and Nathaniel McConnell

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Analysis of Reported Adverse Events With Colonic Stents: An FDA MAUDE Database Study., Daryl Ramai, Matthew DeLuca, Antonio Facciorusso, Andrew Ofosu, Mohit Girotra, James H Tabibian, Eduardo Rodrigues-Pinto, Douglas G Adler, and Monique T Barakat

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Progression to pseudomyxoma peritonei in patients with low grade appendiceal mucinous neoplasms discovered at time of appendectomy., Shelby Reiter, Colin J Rog, Mohamed Alassas, and Evan Ong

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Facebook Live: HMR Weight Management: Insights into Successful Weight Loss, Rick Riess and Frances Broyles

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Ethical Aspects of Artificially Administered Nutrition and Hydration: An ASPEN Position Paper., Denise Baird Schwartz, Albert Barrocas, Maria Giuseppina Annetta, Kathleen Stratton, Carol McGinnis, Gil Hardy, Theodoric Wong, Diego Arenas, Mary Pat Turon-Findley, Rubén Gustavo Kliger, Kelly Green Corkins, Jay Mirtallo, Teruyoshi Amagai, and Peggi Guenter

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Association of Obesity with Cardiovascular Risk Factors and Kidney Disease Outcomes in Primary Proteinuric Glomerulopathies., Paras P Shah, Tammy M Brady, Kevin E C Meyers, Michelle M O'Shaughnessy, Keisha L Gibson, Tarak Srivastava, Jarcy Zee, Daniel Cattran, Katherine Tuttle, Crystal Gadegbeku, Dorey Glenn, Vimal Derebail, Abigail Smith, Chia-Shi Wang, Brenda W Gillespie, Markus Bitzer, and Christine B Sethna

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Plasma MMP-2 and MMP-7 levels are elevated first month after surgery and may promote growth of residual metastases., Hmc Shantha Kumara, Hiromichi Miyagaki, Sajith A Herath, Erica Pettke, Xiaohong Yan, Vesna Cekic, and Richard L Whelan

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Esophageal Necrosis as an Unexpected Complication of Diabetic Ketoacidosis, Hayden Smith and Tricia James

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Role of hospitalization for inflammatory bowel disease in the post-biologic era., Celine R Soriano, Charleston R Powell, Michael Chiorean, and Vlad V Simianu

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Ongoing Global Impact of the COVID-19 Pandemic on Endoscopy: A Subsequent International Survey of 121 Centers From 35 Countries., Sachin Srinivasan, Suneha Sundaram, Fabian Emura, Nageshwar Reddy, Douglas O Faigel, Alessandro Repici, Sravanthi Parasa, and Prateek Sharma

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Facebook Live: New Year, New You: Personalize your plate and start moving, Niki Strealy and Stacey Cochran

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A novel microRNA-based prognostic model outperforms standard prognostic models in patients with acetaminophen-induced acute liver failure., Oliver D Tavabie, Constantine J Karvellas, Siamak Salehi, Jaime L Speiser, Christopher F Rose, Krishna Menon, Andreas Prachalias, Michael A Heneghan, Kosh Agarwal, William M Lee, Mark J W McPhail, Varuna R Aluvihare, United States Acute Liver Failure Study Group, and Oren K Fix (United States Acute Liver Failure Study Group)

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Impact of Image Resolution on Deep Learning Performance in Endoscopy Image Classification: An Experimental Study Using a Large Dataset of Endoscopic Images., Vajira Thambawita, Inga Strümke, Steven A Hicks, Pål Halvorsen, Sravanthi Parasa, and Michael A Riegler

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Author Correction: Gut microbiome pattern reflects healthy ageing and predicts survival in humans., Tomasz Wilmanski, Christian Diener, Noa Rappaport, Sushmita Patwardhan, Jack Wiedrick, Jodi Lapidus, John C Earls, Anat Zimmer, Gustavo Glusman, Max Robinson, James T Yurkovich, Deborah M Kado, Jane A Cauley, Joseph Zmuda, Nancy E Lane, Andrew T Magis, Jennifer C Lovejoy, Leroy Hood, Sean M Gibbons, Eric S Orwoll, and Nathan D Price

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Gut microbiome pattern reflects healthy ageing and predicts survival in humans., Tomasz Wilmanski, Christian Diener, Noa Rappaport, Sushmita Patwardhan, Jack Wiedrick, Jodi Lapidus, John C Earls, Anat Zimmer, Gustavo Glusman, Max Robinson, James T Yurkovich, Deborah M Kado, Jane A Cauley, Joseph Zmuda, Nancy E Lane, Andrew T Magis, Jennifer C Lovejoy, Leroy Hood, Sean M Gibbons, Eric S Orwoll, and Nathan D Price

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From taxonomy to metabolic output: what factors define gut microbiome health?, Tomasz Wilmanski, Noa Rappaport, Christian Diener, Sean M Gibbons, and Nathan D Price

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Acute PR3-ANCA vasculitis in an asymptomatic COVID-19 teenager., Taylor Wintler, Monica Zherebtsov, Susanne Carmack, Rebecca Muntean, and Sarah J Hill

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Improved gastrointestinal profile with diroximel fumarate is associated with a positive impact on quality of life compared with dimethyl fumarate: results from the randomized, double-blind, phase III EVOLVE-MS-2 study., Annette Wundes, Sibyl Wray, Ralf Gold, Barry A Singer, Elzbieta Jasinska, Tjalf Ziemssen, Jerome de Seze, P Repovic, Hailu Chen, Jerome Hanna, Jordan Messer, Catherine Miller, and Robert T Naismith

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Exploration of Lipid Metabolism in Gastric Cancer: A Novel Prognostic Genes Expression Profile., Zhen Xiong, Yao Lin, Yan Yu, Xianghui Zhou, Jun Fan, Colin J Rog, Kailin Cai, Zheng Wang, Zhijie Chang, Guobin Wang, Kaixiong Tao, and Ming Cai

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Alternative management of delayed spontaneous oesophageal perforation by endoscopic stenting., Christina Zhu, Adan Castrodad, and Ariel P Santos

Submissions from 2020

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Effects of diet and exercise on adipocytokine levels in patients with moderate to severe chronic kidney disease., Nihal Aydemir, Mindy M Pike, Aseel Alsouqi, Samuel A E Headley, Katherine Tuttle, Elizabeth E Evans, Charles M Milch, Kelsey A Moody, Michael Germain, Loren Lipworth, Jonathan Himmelfarb, T A Ikizler, and Cassianne Robinson-Cohen

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Minimally invasive sigmoidectomy for diverticular disease decreases inpatient opioid use: Results of a propensity score-matched study., Amir Bastawrous, I-Fan Shih, Yanli Li, and Robert K Cleary

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Planting the Seeds of Health and Resilience, Shawna Beese, Teresa Bigand, and Marian L. Wilson

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Position statement on priorities for artificial intelligence in GI endoscopy: a report by the ASGE Task Force., Tyler M Berzin, Sravanthi Parasa, Michael B Wallace, Seth A Gross, Alessandro Repici, and Prateek Sharma

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BMI influences relationships among health factors for adults with persistent pain who use prescription opioids., Teresa Bigand, Ruth Bindler, Lois James, Kenn Daratha, and Marian Wilson

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Pilot testing an electronic food diary among Registered Nurses working night shifts., Teresa Bigand, Moriah Cason, Tullamora Diede, and Marian Wilson

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Barriers and Facilitators to Healthy Eating among Adult Food Bank Users., Teresa Bigand, Jeremy Dietz, Hannah N Gubitz, and Marian Wilson

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Comment on: Systematic review of the introduction and evaluation of magnetic augmentation of the lower oesophageal sphincter for gastro-oesophageal reflux disease., L Bonavina, N Boyle, C Dunn, T Horbach, T B Knowles, J C Lipham, Brian Louie, S Markar, S F Schppmann, and J Zehetner

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Margetuximab plus pembrolizumab in patients with previously treated, HER2-positive gastro-oesophageal adenocarcinoma (CP-MGAH22-05): a single-arm, phase 1b-2 trial., Daniel V T Catenacci, Yoon-Koo Kang, Haeseong Park, Hope E Uronis, Keun-Wook Lee, Matthew C H Ng, Peter C Enzinger, Se Hoon Park, Philip J Gold, Jill Lacy, Howard S Hochster, Sang Cheul Oh, Yeul Hong Kim, Kristen A Marrone, Ronan J Kelly, Rosalyn A Juergens, Jong Gwang Kim, Johanna C Bendell, Thierry Alcindor, Sun Jin Sym, Eun-Kee Song, Cheng Ean Chee, Yee Chao, Sunnie Kim, A Craig Lockhart, Keith L Knutson, Jennifer Yen, Aleksandra Franovic, Jeffrey L Nordstrom, Daner Li, Jon Wigginton, Jan K Davidson-Moncada, Minori Koshiji Rosales, Yung-Jue Bang, and CP-MGAH22-5 Study Group

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Minimally Invasive Esophagectomy: A Consensus Statement., Robert J Cerfolio, Anne-Sophie Laliberte, Shanda Blackmon, Jelle P Ruurda, Richard van Hillegersberg, Inderpal Sarkaria, and Brian Louie

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Development of a prenatal clinical care pathway for uncomplicated gastroschisis and literature review., S Chabra, S Peterson, and E Cheng

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Post operative pediatric appendicitis nurse-driven discharge: Patient outcomes and nursing perspectives., Michael Chisum, Amber May, Mansen Wang, Ed Hagen, and Robert Weinsheimer

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Multi-Center Analysis of Liver Transplantation for Combined Hepatocellular Carcinoma-Cholangiocarcinoma Liver Tumors., Leigh Anne Dageforde, Neeta Vachharajani, Parissa Tabrizian, Vatche Agopian, Karim Halazun, Erin Maynard, Kristopher Croome, David Nagorney, Johnny C Hong, David Lee, Cristina Ferrone, Erin Baker, William Jarnagin, Alan Hemming, Gabriel Schnickel, Shoko Kimura, Ronald Busuttil, Jessica Lindemann, Sander Florman, Matthew L Holzner, Rami Srouji, Marc Najjar, Lavanya Yohanathan, Jane Cheng, Hiral Amin, Charles A Rickert, Ju Dong Yang, Joohyun Kim, Jennifer Pasko, William C Chapman, and Maria B Majella Doyle

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Characterizing diversity in the tumor-immune microenvironment of distinct subclasses of gastroesophageal adenocarcinomas., S Derks, L K de Klerk, X Xu, T Fleitas, K X Liu, Y Liu, F Dietlein, C Margolis, A M Chiaravalli, A C Da Silva, S Ogino, F G Akarca, G J Freeman, S J Rodig, J L Hornick, E van Allen, B Li, S X Liu, V Thorsson, and A J Bass

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MICOM: Metagenome-Scale Modeling To Infer Metabolic Interactions in the Gut Microbiota., Christian Diener, Sean M Gibbons, and Osbaldo Resendis-Antonio

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Outcomes following early versus delayed cholecystectomy performed for acute cholangitis., Andrew Discolo, Shelby Reiter, Bryce French, Danielle Hayes, Gary Lucas, Lancy Tan, James Scanlan, and Ryan Martinez

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Regression of Barrett's esophagus after magnetic sphincter augmentation: intermediate-term results., Colin P Dunn, Justin C Henning, Jason A Sterris, Paul Won, Caitlin C Houghton, Nikolai A Bildzukewicz, and John C Lipham

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Magnetic sphincter augmentation with hiatal hernia repair: long term outcomes., Colin P Dunn, Jasmine Zhao, Jennifer C Wang, Tanu A Patel, Luke Putnam, Aleeson Eka, Caitlin C Houghton, Nikolai A Bildzukewicz, and John C Lipham

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American Society for Metabolic and Bariatric Surgery 2018 estimate of metabolic and bariatric procedures performed in the United States., Wayne J English, Eric J DeMaria, Matthew M Hutter, Shanu N Kothari, Samer G Mattar, Stacy A Brethauer, and John M Morton

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The Use of Visceral Proteins as Nutrition Markers: An ASPEN Position Paper., David C Evans, Mark R Corkins, Ainsley Malone, Sarah Miller, Kris M Mogensen, Peggi Guenter, Gordon L Jensen, and ASPEN Malnutrition Committee

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Not in the Same Vein: Inflammatory Bowel Disease, Malignancy, and Enterocolic Lymphocytic Phlebitis., Orly N Farber, Alexa Weingarden, Christopher Lee, David R Braxton, David Bingham, Gregory Scott, Nielsen Fernandez-Becker, Daniel Goff, Andrew Shelton, and Cindy Kin

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It's Time to Rethink Our Assumptions About Acute Wilson's Disease., Oren K Fix

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Clinical Best Practice Advice for Hepatology and Liver Transplant Providers During the COVID-19 Pandemic: AASLD Expert Panel Consensus Statement., Oren K Fix, Bilal Hameed, Robert J Fontana, Ryan M Kwok, Brendan M McGuire, David C Mulligan, Daniel S Pratt, Mark W Russo, Michael L Schilsky, Elizabeth C Verna, Rohit Loomba, David E Cohen, Jorge A Bezerra, K Rajender Reddy, and Raymond T Chung

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Telemedicine and Telehepatology During the COVID-19 Pandemic., Oren K Fix and Marina Serper

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Safety and efficacy of magnetic sphincter augmentation dilation., Reid Fletcher, Christy M Dunst, Walaa F Abdelmoaty, Evan T Alicuben, Ealaf Shemmeri, Brett Parker, Dolores Müller, Ahmed M Sharata, Kevin M Reavis, Daniel Davila Bradley, Nikolai A Bildzukewicz, Brian Louie, John C Lipham, and Steven R DeMeester

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A Randomized Trial Comparing Antibiotics with Appendectomy for Appendicitis., David R Flum, Giana H Davidson, Sarah E Monsell, Nathan I Shapiro, Stephen R Odom, Sabrina E Sanchez, F Thurston Drake, Katherine Fischkoff, Jeffrey Johnson, Joe H Patton, Heather Evans, Joseph Cuschieri, Amber K Sabbatini, Brett A Faine, Dionne A Skeete, Mike K Liang, Vance Sohn, Karen McGrane, Matthew E Kutcher, Bruce Chung, Damien W Carter, Patricia Ayoung-Chee, William Chiang, Amy Rushing, Steven Steinberg, Careen S Foster, Shaina M Schaetzel, Thea P Price, Katherine Mandell, Lisa Ferrigno, Matthew Salzberg, Daniel A DeUgarte, Amy H Kaji, Gregory J Moran, Darin Saltzman, Hasan B Alam, Pauline K Park, Lillian S Kao, Callie M Thompson, Wesley H Self, Julianna T Yu, Abigail Wiebusch, Robert J Winchell, Sunday Clark, Anusha Krishnadasan, Erin Fannon, Danielle C Lavallee, Bryan A Comstock, Bonnie Bizzell, Patrick J Heagerty, Larry G Kessler, and David A Talan

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Colon and Rectal Surgery Robotic Training Programs: An Evaluation of Gender Disparities., Katherine E Foley, Kevin M Izquierdo, Madrigal G von Muchow, Amir Bastawrous, Robert K Cleary, and Mark K Soliman

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Prognostic Impact and Utility of Immunoprofiling in the Selection of Patients with Colorectal Peritoneal Carcinomatosis for Cytoreductive Surgery (CRS) and Heated Intraperitoneal Chemotherapy (HIPEC)., Mary Garland-Kledzik, Abhineet Uppal, Yalda Naeini, Stacey L Stern, Richard Erali, Anthony J Scholer, Adam Khader, Juan A Santamaria-Barria, Kathleen Cummins-Perry, Yi Zhou, Konstantinos I Votanopoulos, Perry Shen, Edward A Levine, and Anton J Bilchik

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Prior tonsillectomy is associated with an increased risk of esophageal adenocarcinoma., Katherine S Garman, Teminioluwa A Ajayi, Harold J Boutte, Shih-Ting Chiu, Richard J von Furstenberg, Benjamin R Lloyd, Cecelia Zhang, Mark W Onaitis, Shein-Chung Chow, and Shannon J McCall

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Management of early hepatocellular carcinoma: results of the Delphi consensus process of the Americas Hepato-Pancreato-Biliary Association., Sepideh Gholami, Lauren M Perry, Jason W Denbo, Kenneth Chavin, Philippa H Newell, Quan Ly, Charles St Hill, Gareth Morris-Stiff, Jonathan Kessler, Timothy L Frankel, Neehar D Parikh, Prejesh Philips, George Salti, Toms Augustin, Federico Aucejo, Meelie Debroy, Natalie Coburn, and Susanne G Warner

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Primary Sclerosing Cholangitis: Epidemiology, Genetics, Diagnosis, and Current Management., Eric Gochanour, Channa Jayasekera, and Kris V Kowdley

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Organ Preservation in the Treatment of Stage II and III Rectal Cancer., Ed Hagen and Robert K Cleary

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Perianal basal cell carcinoma: a common cancer in an uncommon location., Ed Hagen, Nathan Hite, John A Griffin, and Rodney Kratz

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Laparoscopic Transhiatal Esophagectomy for Invasive Esophageal Adenocarcinoma., Kelly R Haisley, Walaa F Abdelmoaty, and Christy M Dunst

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The Modern Age of POEM: the Past, Present and Future of Per-Oral Endoscopic Myotomy., Kelly R Haisley and Lee L Swanström

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Full-thickness resection device (FTRD) for treatment of upper gastrointestinal tract lesions: the first international experience., Kaveh Hajifathalian, Yervant Ichkhanian, Qais Dawod, Alexander Meining, Arthur Schmidt, Nicholas Glaser, Kia Vosoughi, David L Diehl, Ian S Grimm, Theodore James, Adam W Templeton, Jason B Samarasena, Nabil El Hage Chehade, John G Lee, Kenneth J Chang, Meir Mizrahi, Mohammed Barawi, Shayan Irani, Shai Friedland, Paul Korc, Abdul Aziz Aadam, Mohammad Al-Haddad, Thomas E Kowalski, George Smallfield, Gregory G Ginsberg, Norio Fukami, Michael Lajin, Nikhil A Kumta, Shou-Jiang Tang, Yehia Naga, Stuart K Amateau, Franklin Kasmin, Martin Goetz, Stefan Seewald, Vivek Kumbhari, Saowanee Ngamruengphong, Srihari Mahdev, Saurabh Mukewar, Kartik Sampath, David L Carr-Locke, Mouen A Khashab, and Reem Z Sharaiha

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How we treat left-sided vs right-sided colon cancer., Diana L Hanna and Heinz-Josef Lenz

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Number needed to treat with ursodeoxycholic acid therapy to prevent liver transplantation or death in primary biliary cholangitis., Maren H Harms, Rozanne C de Veer, Willem J Lammers, Christophe Corpechot, Douglas Thorburn, Harry L A Janssen, Keith D Lindor, Palak J Trivedi, Gideon M Hirschfield, Albert Pares, Annarosa Floreani, Marlyn J Mayo, Pietro Invernizzi, Pier Maria Battezzati, Frederik Nevens, Cyriel Y Ponsioen, Andrew L Mason, Kris V Kowdley, Bettina E Hansen, Henk R van Buuren, and Adriaan J van der Meer

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Endoscopic transpapillary stenting for the management of acute cholecystitis., Danielle Hayes, Gary Lucas, Andrew Discolo, Bryce French, and Sean Wells

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Is interval appendectomy really needed? A closer look at neoplasm rates in adult patients undergoing interval appendectomy after complicated appendicitis., Danielle Hayes, Shelby Reiter, Ed Hagen, Gary Lucas, Isabelle Chu, Tobias Muñiz, and Ryan Martinez

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An atypical case of necrotizing fasciitis secondary to perforated cecal cancer., Laura S Heidelberg, Erica Pettke, Teresa E Wagner, and Lauren Angotti

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Thrombospondin-1 counteracts the p97 inhibitor CB-5083 in colon carcinoma cells., Nam-Gu Her, Santosh Kesari, and Elmar Nurmemmedov

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Development and Pilot Testing of the Inflammatory Bowel Disease Nutrition Care Pathway., Caroline Hwang, Kelly Issokson, Catherine Giguere-Rich, Swapna Reddy, Andrew Tinsley, Welmoed K Van Deen, Harry Bray, Donald Lum, Humberto Aguilar, Timothy L Zisman, Ziad Younes, Damara Crate, Ridhima Oberai, Alandra Weaver, Gil Melmed, Corey Siegel, and Jason K Hou

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A large multicenter cohort on the use of full-thickness resection device for difficult colonic lesions., Y Ichkhanian, K Vosoughi, D L Diehl, I S Grimm, T W James, A W Templeton, K Hajifathalian, J L Tokar, J B Samarasena, N El Hage Chehade, J Lee, K Chang, M Mizrahi, M Barawi, S Irani, S Friedland, Paul Korc, A A Aadam, M A Al-Haddad, T E Kowalski, A Novikov, G Smallfield, G G Ginsberg, V M Oza, D Panuu, N Fukami, H Pohl, Michael Lajin, N A Kumta, S J Tang, Y M Naga, S K Amateau, G O I Brewer, V Kumbhari, R Sharaiha, and Mouen A Khashab

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Determinant factors on differences in survival for gastric cancer between the US and Japan using nationwide databases., Yuri Ito, Isao Miyashiro, Takashi Ishikawa, Kohei Akazawa, Keisuke Fukui, Hitoshi Katai, Souya Nunobe, Ichiro Oda, Yoh Isobe, Shunichi Tsujitani, Hiroyuki Ono, Satoshi Tanabe, Takeo Fukagawa, Satoshi Suzuki, Yoshihiro Kakeji, Mitsuru Sasako, Anton J Bilchik, and Manabu Fujita

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Modulation of Immune Checkpoints by Chemotherapy in Human Colorectal Liver Metastases., Neda Jabbari, Heidi L Kenerson, Christopher Lausted, Xiaowei Yan, Changting Meng, Kevin M Sullivan, Priyanka Baloni, Dani E Bergey, Venu G Pillarisetty, Leroy Hood, Raymond S Yeung, and Qiang Tian

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Institutional prevalence of class III obesity modifies risk of adverse obstetrical outcomes., Jennifer L Katz Eriksen, Vivienne L Souter, Peter G Napolitano, and Suchitra Chandrasekaran

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Cholecystectomy for Biliary Pancreatitis Is Often Not Performed During Index Hospitalization and Is Associated With Worse Outcomes., Divyanshoo R Kohli, Madhav Desai, Kevin F Kennedy, Sravanthi Parasa, and Prateek Sharma

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Patterns of Alcohol Use After Early Liver Transplantation for Alcoholic Hepatitis., Brian P Lee, Gene Y Im, John P Rice, Ann Lazar, Ethan Weinberg, Hyosun Han, Haripriya Maddur, R Mark Ghobrial, George Therapondos, Christine Hsu, Oren K Fix, Sheila Eswaran, Kirti Shetty, Jag Chhatwal, Ozden O Dalgic, Neha Jakhete, Constance Mobley, David W Victor, Neil Mehta, Lisanne Dinges, Mary Rinella, Thomas D Schiano, Michael R Lucey, and Norah Terrault

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Longitudinal analysis reveals transition barriers between dominant ecological states in the gut microbiome., Roie Levy, Andrew T Magis, John C Earls, Ohad Manor, Tomasz Wilmanski, Jennifer Lovejoy, Sean M Gibbons, Gilbert S Omenn, Leroy Hood, and Nathan D Price

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Multicenter validation of association between decline in MRI-PDFF and histologic response in nonalcoholic steatohepatitis., Rohit Loomba, Brent A Neuschwander-Tetri, Arun Sanyal, Naga Chalasani, Anna Mae Diehl, Norah Terrault, Kris Kowdley, Srinivasan Dasarathy, David Kleiner, Cynthia Behling, Joel Lavine, Mark Van Natta, Michael Middleton, James Tonascia, and Claude Sirlin

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Commentary: Defining low-risk lesions for esophageal preservation informed by resecting the organ., Brian Louie

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Response to the Comment on "Objective Evidence of Reflux Control After Magnetic Sphincter Augmentation: One Year Results From a Post Approval Study"., Brian Louie, Christy Dunst, and John C Lipham

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Alpha1-Antitrypsin Deficiency: A Cause of Chronic Liver Disease., Vignan Manne and Kris V Kowdley

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Health and disease markers correlate with gut microbiome composition across thousands of people., Ohad Manor, Chengzhen L Dai, Sergey A Kornilov, Brett Smith, Nathan D Price, Jennifer C Lovejoy, Sean M Gibbons, and Andrew T Magis