The Digestive Health Institute is a network of highly trained doctors and surgeons who treat disorders of the gastrointestinal (GI) tract, as well as the liver, gallbladder and pancreas. As it becomes increasingly complex to treat digestive diseases and GI cancer, optimizing care relies more on the close collaboration of experts from across disciplines.

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Submissions from 2024

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Type B Lactic Acidosis: A Very Rare but Fatal Complication of Gastrointestinal Solid Tumor., Fuad I Abaleka, Genanew Bedanie, Diego Olavarria Bernal, Selome F Yewedalsew, and Tasur Seen

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Early recapture of response with tofacitinib 10 mg twice daily in patients with ulcerative colitis in OCTAVE Open following dose reduction or treatment interruption in OCTAVE Sustain., Jessica R Allegretti, Krisztina B Gecse, Michael Chiorean, Marjorie Argollo, Xiang Guo, Nervin Lawendy, Chinyu Su, Rajiv Mundayat, Jerome Paulissen, Leonardo Salese, and Peter M Irving

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Dietary intake and continuous blood glucose measurement in nurses working either 12-hour day shifts or night shifts, Rachel Carlson, Teresa Rangel, Lindsey Miller, and Sushana Sudhi

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Real-world clinical outcomes and healthcare costs in patients with Crohn's disease treated with vedolizumab versus ustekinumab in the United States., Michael Chiorean, Jeanne Jiang, Ninfa Candela, Grace Chen, Hela Romdhani, Dominick Latremouille-Viau, Sherry Shi, Rebecca Bungay, Annie Guerin, and Tao Fan

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Same day discharge colon surgery: is it financially worth it?, Karleigh R Curfman, Gabrielle E Blair, Callan L Kosnik, Sunshine A Pille, Michael E Parsons, Chirag A Shah, Christopher C Neighorn, and Laila Rashidi

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Use of a Novel Artificial Intelligence System Leads to the Detection of Significantly Higher Number of Adenomas During Screening and Surveillance Colonoscopy: Results From a Large, Prospective, US Multicenter, Randomized Clinical Trial., Madhav Desai, Karlee Ausk, Donald Brannan, Rajiv Chhabra, Walter Chan, Michael Chiorean, Seth A Gross, Mohit Girotra, Gregory Haber, Reed B Hogan, Bobby Jacob, Sreeni Jonnalagadda, Lulu Iles-Shih, Navin Kumar, Joanna Law, Linda Lee, Otto Lin, Meir Mizrahi, Paulo Pacheco, Sravanthi Parasa, Jennifer Phan, Vonda Reeves, Amrita Sethi, David Snell, James Underwood, Nanda Venu, Kavel Visrodia, Alina Wong, Jessica Winn, Cindy Haden Wright, and Prateek Sharma

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Metagenomic estimation of dietary intake from human stool., Christian Diener and Sean M Gibbons

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Differences in nutritional profile by chronotype among 12-h day shift and night shift nurses., Rachel Faulkner, Teresa Rangel, Rebecca Penders, Trisha Saul, Ross Bindler, Lindsey Miller, and Marian Wilson

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Randomized Placebo-Controlled, Biomarker-Stratified Phase Ib Microbiome Modulation in Melanoma: Impact of Antibiotic Preconditioning on Microbiome and Immunity., Isabella C Glitza, Yongwoo David Seo, Christine N Spencer, Jennifer R Wortman, Elizabeth M Burton, Farah A Alayli, Christopher P Loo, Shikha Gautam, Ashish Damania, Julie Densmore, Justin Fairchild, Christopher R Cabanski, Matthew C Wong, Christine B Peterson, Brian Weiner, Nathan Hicks, John G Auniņš, Christopher McChalicher, Emily Walsh, Michael T Tetzlaff, Omid Hamid, Patrick A Ott, Genevieve M Boland, Ryan J Sullivan, Kenneth F Grossmann, Nadim J Ajami, Theresa LaVallee, Matthew R Henn, Hussein A Tawbi, and Jennifer A Wargo

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Body Mass Index and Mortality in Cardiogenic Shock., Maya Guglin, Elric Zweck, Manreet Kanwar, Shashank S Sinha, Arvind Bhimaraj, Borui Li, Jacob Abraham, Saraschandra Vallabhajosyula, Jaime Hernandez-Montfort, Rachna Kataria, Daniel Burkhoff, and Navin K Kapur

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Correction: Management of symptomatic, asymptomatic, and recurrent hiatal hernia: a systematic review and meta-analysis., Nader M Hanna, Sunjay S Kumar, Amelia T Collings, Yagnik K Pandya, James Kurtz, Keshav Kooragayala, Meghan W Barber, Mykola Paranyak, Marina Kurian, Jeffrey Chiu, Ahmed Abou-Setta, Mohammed T Ansari, Bethany J Slater, Geoffrey P Kohn, and Shaun Daly

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Management of symptomatic, asymptomatic, and recurrent hiatal hernia: a systematic review and meta-analysis., Nader M Hanna, Sunjay S Kumar, Amelia T Collings, Yagnik K Pandya, James Kurtz, Keshav Kooragayala, Meghan W Barber, Mykola Paranyak, Marina Kurian, Jeffrey Chiu, Ahmed Abou-Setta, Mohammed T Ansari, Bethany J Slater, Geoffrey P Kohn, and Shaun Daly

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Human-in-the-loop informed deep learning rectal tumor segmentation on pre-treatment MRI, Michael Kong, Marka R Crittenden, Michael J. Gough, Kristina H Young, and See full list of authors in comments

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Peristomal cutaneous amebiasis causing rapidly progressive necrotic wound of a left lower quadrant end colostomy., Debra Lai, Byung Kyu Kim, and Amir Bastawrous

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Physician perceptions on the current and future impact of artificial intelligence to the field of gastroenterology., Cadman L Leggett, Sravanthi Parasa, Alessandro Repici, Tyler M Berzin, Seth A Gross, and Prateek Sharma

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Evolving Gender Parity of Industry Research Funding to Surgical Oncologists: An Open Payments Database Analysis., Jason M Lizalek, Brooke J Fitzpatrick, Brianna L Foley, Collin E Dougherty, Anton J Bilchik, Joshua M V Mammen, and Juan A Santamaria-Barria

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Five-Year Outcomes from a Prospective Study on the Safety and Efficacy of Phasix-ST Mesh Use at the Hiatus During Paraesophageal Hernia Repair., Sarah C McKay, Christy M Dunst, Daniel Davila-Bradley, Kevin M Reavis, and Steven R DeMeester

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Consensus statements on the current landscape of artificial intelligence applications in endoscopy, addressing roadblocks, and advancing artificial intelligence in gastroenterology., Sravanthi Parasa, Tyler Berzin, Cadman Leggett, Seth Gross, Alessandro Repici, Omer F Ahmad, Austin Chiang, Nayantara Coelho-Prabhu, Jonathan Cohen, Evelien Dekker, Rajesh N Keswani, Charles E Kahn, Cesare Hassan, Nicholas Petrick, Peter Mountney, Jonathan Ng, Michael Riegler, Yuichi Mori, Yutaka Saito, Shyam Thakkar, Irving Waxman, Michael Bradley Wallace, and Prateek Sharma

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Association between class III obesity and overall survival in previously untreated younger patients with acute myeloid leukemia enrolled on SWOG S1203, Mary-Elizabeth Percival, Michelle Zhang, Megan Othus, Kerry McMillen, Harry Erba, Guillermo Garcia-Manero, John Pagel, and Mohamed Sorror

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Clostridioides difficile Colitis., Luke Pumiglia, Lexi Wilson, and Laila Rashidi

Nursing Dietary Intake and Continuous Blood Glucose Measurement, Teresa Rangel and Rachel Carlson

Relationships between Dietary Intake and Alertness Among 12-Hour Shift Nurses, Teresa Rangel, Charis Williams, and Ross Bindler

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Socially vulnerable patients are more likely to fail outpatient management of symptomatic cholelithiasis., Udai S Sibia, John R Klune, Cristina B Feather, Deanna Rider, Douglas Hanes, and Richard Essner

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Early Experiences With Bundled Payments for Care Improvement for Major Bowel Surgery., Udai S Sibia, John R Klune, Said Saiolghalam, and Anton J Bilchik

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The Milan score: A novel manometric tool for a more efficient diagnosis of gastro-esophageal reflux disease., Stefano Siboni, Marco Sozzi, Ivan Kristo, Sara Boveri, Benjamin D Rogers, Nicola De Bortoli, Anthony Hobson, Brian E Louie, Yeong Yeh Lee, Salvatore Tolone, Elisa Marabotto, Pierfrancesco Visaggi, Jordan Haworth, Megan L Ivy, Garrett Greenan, Takahiro Masuda, Roberto Penagini, Benedetta Barcella, Marina Coletta, Dimitrios Theodorou, Tania Triantafyllou, Chiara Facchini, Vincent Tee, Luigi Bonavina, Lorenzo Cusmai, Sebastian F Schoppmann, Edoardo Savarino, Emanuele Asti, and C Prakash Gyawali

“A Pinch of Salt – A Podcast by ERA”, Katherine Tuttle

“Cases in Diabetes, Kidney, and Cardio-Renal-Metabolic Disease”, Katherine Tuttle

“Glycemic Management in Persons with Diabetes and CKD”, Katherine Tuttle

“Kidney Disease and Obesity”, Katherine Tuttle

“Miracle weight-loss drugs could halt kidney disease too”, Katherine Tuttle

National Geographic Interview feature article, Katherine Tuttle

“Transformation of CKD Care to Delivery Kidney Health”, Katherine Tuttle

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Efficacy and safety of aldosterone synthase inhibition with and without empagliflozin for chronic kidney disease: a randomised, controlled, phase 2 trial., Katherine R Tuttle, Sibylle J Hauske, Maria Eugenia Canziani, Maria Luiza Caramori, David Cherney, Lisa Cronin, Hiddo J L Heerspink, Christian Hugo, Masaomi Nangaku, Ricardo Correa Rotter, Arnold Silva, Shimoli V Shah, Zhichao Sun, Dorothea Urbach, Dick de Zeeuw, Peter Rossing, and ASi in CKD group

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Anal Condyloma and Human Papillomavirus: Recognition, Treatment, and Prevention., Kenley R Unruh and Debra D Lai

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Ambulatory Robotic Colectomy: Factors Affecting and Affected by Postoperative Opioid Use., Michael M Vu, Jace J Franko, Anna Buzadzhi, Beau Prey, Maksim Rusev, Marta M Lavery, and Laila Rashidi

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Achievement of clinical, endoscopic, and histologic outcomes in patients with ulcerative colitis treated with etrasimod, and association with fecal calprotectin and C-reactive protein: results from the Phase 2 OASIS trial., Andres J Yarur, Michael Chiorean, Julián Panés, Vipul Jairath, Jinkun Zhang, Christopher J Rabbat, William J Sandborn, Séverine Vermeire, and Laurent Peyrin-Biroulet

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Oncologic outcomes following transanal total mesorectal excision: the United States experience., Makda Getachew Zewde, Daniel K Peyser, Allen T Yu, Antoinette Bonaccorso, Erin Moshier, Karim Alavi, Robert Goldstone, John H Marks, Justin A Maykel, Elisabeth C McLemore, Dana Sands, Scott R Steele, Steven D Wexner, Mark Whiteford, and Patricia Sylla

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Optimization of a standardized letter of recommendation for faculty who wish to support candidates applying to surgical training programs., Clare Zipf-Sigler, Alisha L Nguyen, Amber Huang, Ryan De Leon, Shannon Helbling, Eliza B Littleton, and Anjali S Kumar

Submissions from 2023

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Early recapture of response with tofacitinib 10 mg twice daily in patients with ulcerative colitis in OCTAVE Open following dose reduction or treatment interruption in OCTAVE Sustain., Jessica R Allegretti, Krisztina B Gecse, Michael Chiorean, Marjorie Argollo, Xiang Guo, Nervin Lawendy, Chinyu Su, Rajiv Mundayat, Jerome Paulissen, Leonardo Salese, and Peter M Irving

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Gut microbiota analyses of inflammatory bowel diseases from a representative Saudi population., Raed M Alsulaiman, Abdulaziz A Al-Quorain, Fahad A Al-Muhanna, Stanley Piotrowski, Ezzeddin A Kurdi, Chittibabu Vatte, Ahmed A Alquorain, Noorah H Alfaraj, Abdulaziz M Alrezuk, Fred L Robinson, Alexa K Dowdell, Turki A Alamri, Lauren Hamilton, Hetal Lad, Hui Gao, Divya Gandla, Brendan J Keating, Ryan Meng, Brian D. Piening, and Amein K Al-Ali

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American Society for Gastrointestinal Endoscopy guideline on management of post-liver transplant biliary strictures: methodology and review of evidence., Stuart K Amateau, Divyanshoo R Kohli, Madhav Desai, Srinath Chinnakotla, M Edwyn Harrison, Jean M Chalhoub, Nayantara Coelho-Prabhu, Sherif E Elhanafi, Nauzer Forbes, Larissa L Fujii-Lau, Richard S Kwon, Jorge D Machicado, Neil B Marya, Swati Pawa, Wenly Ruan, Sunil G Sheth, Nikhil R Thiruvengadam, Nirav C Thosani, Bashar J Qumseya, and ASGE Standards of Practice Committee Chair

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Identifying barriers to shared decision-making about bariatric surgery in two large health systems., David Arterburn, Leah Tuzzio, Jane Anau, Cara C Lewis, Neely Williams, Anita Courcoulas, Diana Stilwell, Ali Tavakkoli, Bestoun Ahmed, Margie Wilcox, Gary S Fischer, Kathleen Paul, Matt Handley, Anirban Gupta, and Kathleen McTigue

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Nutrition support teams: Institution, evolution, and innovation., Albert Barrocas, Denise Baird Schwartz, Bruce R Bistrian, Peggi Guenter, Charles Mueller, Ronni Chernoff, and Jeanette M Hasse

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Health-care expenditures are less for minimally invasive than open colectomy for colon cancer: A US commercial claims database analysis., Amir L Bastawrous, I-Fan Shih, Yanli Li, Marissa Khalil, Biruk Almaz, and Robert K Cleary

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Impact of Eating a Carbohydrate-Restricted Diet on Cortical Atrophy in a Cross-Section of Amyloid Positive Patients with Alzheimer's Disease: A Small Sample Study., Jennifer Bramen, Prabha Siddarth, Emily S Popa, Gavin T Kress, Molly Rapozo, John F Hodes, Aarthi Ganapathi, Colby B Slyapich, Ryan M. Glatt, Kyron P Pierce, Verna R Porter, Claudia L Wong, Mihae Kim, Richelin V Dye, Stella Panos, Tess Bookheimer, Tori Togashi, Spencer Loong, Cyrus A Raji, Susan Y Bookheimer, Jared C Roach, and David A Merrill

Results from an expanded phase 1 trial of botensilimab, a multifunctional anti-CTLA-4, plus balstilimab (anti-PD-1) for metastatic heavily pretreated microsatellite stable colorectal cancer, AJ Bullock, RE Sanborn, and See all authors in comments

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American Society for Gastrointestinal Endoscopy guideline on post-ERCP pancreatitis prevention strategies: methodology and review of evidence., James L Buxbaum, Martin Freeman, Stuart K Amateau, Jean M Chalhoub, Aneesa Chowdhury, Nayantara Coelho-Prabhu, Rishi Das, Madhav Desai, Sherif E Elhanafi, Nauzer Forbes, Larissa L Fujii-Lau, Divyanshoo R Kohli, Richard S Kwon, Jorge D Machicado, Neil B Marya, Swati Pawa, Wenly H Ruan, Jonathan Sadik, Sunil G Sheth, Nikhil R Thiruvengadam, Nirav C Thosani, Selena Zhou, and Bashar J Qumseya

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American Society for Gastrointestinal Endoscopy guideline on post-ERCP pancreatitis prevention strategies: summary and recommendations., James L Buxbaum, Martin Freeman, Stuart K Amateau, Jean M Chalhoub, Nayantara Coelho-Prabhu, Madhav Desai, Sherif E Elhanafi, Nauzer Forbes, Larissa L Fujii-Lau, Divyanshoo R Kohli, Richard S Kwon, Jorge D Machicado, Neil B Marya, Swati Pawa, Wenly H Ruan, Sunil G Sheth, Nikhil R Thiruvengadam, Nirav C Thosani, and Bashar J Qumseya

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Personalized Clostridioides difficile engraftment risk prediction and probiotic therapy assessment in the human gut, Alex Carr, Nitin S Baliga, Christian Diener, and Sean M Gibbons

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Direct Oral Anticoagulants and Warfarin Safety in Rural Patients with Obesity., Zachary R Caverley, Ross J Bindler, Pamela Soh, and Sherri Mendelson

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Impact of Food Environments on Obesity Rates: A State-Level Analysis., Elizabeth Cerceo, Elena Sharma, Anne Boguslavsky, and Jean-Sebastien Rachoin

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Liver Metastases and Immune Checkpoint Inhibitor Efficacy in Patients With Refractory Metastatic Colorectal Cancer: A Secondary Analysis of a Randomized Clinical Trial., Eric X Chen, Jonathan M Loree, Emma Titmuss, Derek J Jonker, Hagen F Kennecke, Scott Berry, Felix Couture, Chaudharry E Ahmad, John R Goffin, Petr Kavan, Mohammed Harb, Bruce Colwell, Setareh Samimi, Benoit Samson, Tahir Abbas, Nathalie Aucoin, Francine Aubin, Sheryl Koski, Alice C Wei, Dongsheng Tu, and Chris J O'Callaghan

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Modeling of Treatment Outcomes with Tofacitinib Maintenance Therapy in Patients with Ulcerative Colitis: A Post Hoc Analysis of Data from the OCTAVE Clinical Program., Michael Chiorean, Marco Daperno, Charlie W Lees, Gianluca Bonfanti, Dimitrios Soudis, Irene Modesto, J Jasper Deuring, and Roger A Edwards

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Consensus classification of pediatric hepatocellular tumors: A report from the Children's Hepatic tumors International Collaboration (CHIC)., Soo-Jin Cho, Sarangarajan Ranganathan, Rita Alaggio, Rudolf Maibach, Yukichi Tanaka, Takeshi Inoue, Ivo Leuschner, Ronald de Krijger, Christian Vokuhl, Mark Krailo, Marcio Malogolowkin, Rebecka Meyers, Piotr Czauderna, Eiso Hiyama, Marc Ansari, Bruce Morland, Angela Trobaugh-Lotrario, Allison F O'Neill, Arun Rangaswami, Beate Häberle, and Dolores López-Terrada

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Tirzepatide and potential use for metabolically healthy obesity., Sidar Copur, Cem Tanriover, Furkan Yavuz, Katherine R Tuttle, and Mehmet Kanbay

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Comparison of robotic versus laparoscopic right colectomy node retrieval in the obese population., Karleigh R Curfman, Jessica M Gowing, Ruben M Lesnick, James M Scanlan, Ulrik G Wallin, John A Griffin, and Laila Rashidi

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Piperacillin-Tazobactam Compared With Cefoxitin as Antimicrobial Prophylaxis for Pancreatoduodenectomy: A Randomized Clinical Trial., Michael I D'Angelica, Ryan J Ellis, Jason B Liu, Brian C Brajcich, Mithat Gönen, Vanessa M Thompson, Mark E Cohen, Susan K Seo, Emily C Zabor, Michele L Babicky, David J Bentrem, Stephen W Behrman, Kimberly A Bertens, Scott A Celinski, Carlos H F Chan, Mary Dillhoff, Matthew E B Dixon, Carlos Fernandez-Del Castillo, Sepideh Gholami, Michael G House, Paul J Karanicolas, Harish Lavu, Shishir K Maithel, John C McAuliffe, Mark J Ott, Bradley N Reames, Dominic E Sanford, Umut Sarpel, Courtney L Scaife, Pablo E Serrano, Travis Smith, Rebecca A Snyder, Mark S Talamonti, Sharon M Weber, Adam C Yopp, Henry A Pitt, and Clifford Y Ko

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Results from a phase 1a/1b study of botensilimab (BOT), a novel innate/adaptive immune activator, plus balstilimab (BAL; anti-PD-1 antibody) in metastatic heavily pretreated microsatellite stable colorectal cancer (MSS CRC)., Anthony B. El-Khoueiry, K A Margolin, Rachel E Sanborn, and See all authors in comments

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Pemphigus vulgaris presenting with epigastric pain., Marawan Elmassry, Jerapas Thongpiya, Pitchaporn Yingchoncharoen, Jali Garza, Matthew Soape, and Kanak Das

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American Society for Gastrointestinal Endoscopy guideline on endoscopic submucosal dissection for the management of early esophageal and gastric cancers: summary and recommendations., Nauzer Forbes, Sherif E Elhanafi, Mohammad A Al-Haddad, Nirav C Thosani, Peter V Draganov, Mohamed O Othman, Eugene P Ceppa, Vivek Kaul, Michael M Feely, Ilyas Sahin, James L Buxbaum, Audrey H Calderwood, Jean M Chalhoub, Nayantara Coelho-Prabhu, Madhav Desai, Larissa L Fujii-Lau, Divyanshoo R Kohli, Richard S Kwon, Jorge D Machicado, Neil B Marya, Swati Pawa, Wenly Ruan, Sunil G Sheth, Andrew C Storm, Nikhil R Thiruvengadam, and Bashar J Qumseya

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ASGE Guideline on the role of endoscopy in the diagnosis of malignancy in biliary strictures of undetermined etiology: Summary and Recommendations., Larissa L Fujii-Lau, Nirav C Thosani, Mohammad Al-Haddad, Jared Acoba, Curtis J Wray, Rodrick Zvavanjanja, Stuart K Amateau, James L Buxbaum, Audrey H Calderwood, Jean M Chalhoub, Nayantara Coelho-Prabhu, Madhav Desai, Sherif E Elhanafi, Douglas S Fishman, Nauzer Forbes, Laith H Jamil, Terry L Jue, Divyanshoo R Kohli, Richard S Kwon, Joanna K Law, Jeffrey K Lee, Jorge D Machicado, Neil B Marya, Swati Pawa, Wenly Ruan, Mandeep S Sawhney, Sunil G Sheth, Andrew Storm, Nikhil R Thiruvengadam, Bashar J Qumseya, and ASGE Standards of Practice Committee Chair (2020-2023)

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ASGE Guideline on role of endoscopy in the diagnosis of malignancy in biliary strictures of undetermined etiology: Methodology and Review of Evidence., Larissa L Fujii-Lau, Nirav C Thosani, Mohammad Al-Haddad, Jared Acoba, Curtis J Wray, Rodrick Zvavanjanja, Stuart K Amateau, James L Buxbaum, Sachin Wani, Audrey H Calderwood, Jean M Chalhoub, Nayantara Coelho-Prabhu, Madhav Desai, Sherif E Elhanafi, Douglas S Fishman, Nauzer Forbes, Laith H Jamil, Terry L Jue, Divyanshoo R Kohli, Richard S Kwon, Joanna K Law, Jeffrey K Lee, Jorge D Machicado, Neil B Marya, Swati Pawa, Wenly Ruan, Mandeep S Sawhney, Sunil G Sheth, Andrew Storm, Nikhil R Thiruvengadam, Bashar J Qumseya, and ASGE Standards of Practice Committee Chair (2020-2023)

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Spatial profiling of cancer-associated fibroblasts of sporadic early onset colon cancer microenvironment., Satoru Furuhashi, Matias A Bustos, Shodai Mizuno, Suyeon Ryu, Yalda Naeini, Anton J Bilchik, and Dave SB Hoon

Temporal shift in heart failure diagnoses among hospitalized patients within a large US integrated health system, Tyler Gluckman, ST Chiu, J Remick, and See full list of authors in comments

363 Billion Reasons to Care: Reversing the Risking Tide of Cardiovascular Events, Tyler Gluckman and H Page

Hemodynamic Profile of Obesity in Cardiogenic Shock, ME Guglin, Jacob Abraham, and See full list of authors in comments

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Monitoring and Surveillance of Patients with Gastroenteropancreatic Neuroendocrine Tumors Undergoing Radioligand Therapy., Thorvardur R Halfdanarson, Nadine Mallak, Scott Paulson, Chandrikha Chandrasekharan, Mona Natwa, Ayse Tuba Kendi, and Hagen F Kennecke

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Biliary and pancreatic stents., Samuel Han; Jorge V Obando; Amit Bhatt; Juan Carlos Bucobo; Dennis Chen; Andrew P Copland; Koushik K Das; Mohit Girotra; Allon Kahn; Kumar Krishnan; Sonali S Sakaria; Monica Saumoy; Guru Trikudanathan; Arvind J Trindade; Julie Yang; Ryan J Law; ASGE Technology Committee Chair; David R Lichtenstein; and (previous Committee Chair, 2019-2021)

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Serum miRNA profiles are altered in patients with primary sclerosing cholangitis receiving high-dose ursodeoxycholic acid., Jessica T Hochberg, Aalam Sohal, Priya Handa, Bryan D Maliken, Take-Kyun Kim, Kai Wang, Eric Gochanour, Yu Li, J Bart Rose, James E Nelson, Keith D Lindor, Nicholas F LaRusso, and Kris V Kowdley

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A Diagnostic Conundrum - Small bowel obstruction from undiagnosed endometriosis following uterine perforation., Erina Horikawa, Carmen R Abbe, Brian E Staley, and Luay Ailabouni

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Generally-healthy individuals with aberrant bowel movement frequencies show enrichment for microbially-derived blood metabolites associated with impaired kidney function., James P Johnson, Christian Diener, Anne E Levine, Tomasz Wilmanski, David L Suskind, Alexandra Ralevski, Jennifer J Hadlock, Andrew T Magis, Leroy Hood, Noa Rappaport, and Sean M Gibbons

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Management of pediatric toxic ingestions in the emergency department., Mia Kanak, Stacy M Tarango, and Deborah R Liu

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The risk for chronic kidney disease in metabolically healthy obese patients: A systematic review and meta-analysis., Mehmet Kanbay, Sidar Copur, Dimitrie Siriopol, Abdullah B Yildiz, Metehan Berkkan, Kathherine R Tuttle, and Carmine Zoccali

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Hormone Receptor-Positive Breast Cancer Sensitive to Pembrolizumab: Evidence of the Pathogenicity of the MLH1 Variant 1835del3., Henry G Kaplan, Jeffrey R Whiteaker, Brianna Nelson, Richard G Ivey, Travis D Lorentzen, Uliana Voytovich, Lei Zhao, David J Corwin, Robert Resta, and Amanda G Paulovich

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NCI Rectal-Anal Task Force consensus recommendations for design of clinical trials in rectal cancer., Hagen F Kennecke, Rebecca Auer, May Cho, N Arvind Dasari, Cynthia Davies-Venn, Cathy Eng, Jennifer Dorth, Julio Garcia-Aguilar, Manju George, Karyn A Goodman, Lillian Kreppel, Joshua E Meyer, Jose Monzon, Leonard Saltz, Deborah Schrag, J Joshua Smith, Jason A Zell, Prajnan Das, and National Cancer Institute Rectal-Anal Task Force

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A Novel Noninvasive Device and Method for Assessing Endothelial Function Is Associated With Measures of Obesity and Fitness., Kellen A Knowles, Kerry J Stewart, Pamela Ouyang, Kathy Magliato, Michael D Whitt, and Harry A Silber

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American Society for Gastrointestinal Endoscopy guideline on management of post-liver transplant biliary strictures: summary and recommendations., Divyanshoo R Kohli, Stuart K Amateau, Madhav Desai, Srinath Chinnakotla, M Edwyn Harrison, Jean M Chalhoub, Nayantara Coelho-Prabhu, Sherif E Elhanafi, Nauzer Forbes, Larissa L Fujii-Lau, Richard S Kwon, Jorge D Machicado, Neil B Marya, Swati Pawa, Wenly Ruan, Sunil G Sheth, Nikhil R Thiruvengadam, Nirav C Thosani, Bashar J Qumseya, and ASGE Standards of Practice Committee Chair

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The Effect of Preoperative Carbohydrate Intake on Length of Stay and Postoperative Recovery Following Laparoscopic Living Donor Nephrectomy., Morgan Kuiper, Melanie Gillingham, Julie Martin, Daniella Gardner, and Sandra Van Calcar

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Incarcerated Prolapsed Sigmoid Intussusception Presenting as Rectal Prolapse Without a Lead Point., Debra Lai, Marta M Lavery, and Ulrik Wallin

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Apposition of Fibroblasts With Metaplastic Gastric Cells Promotes Dysplastic Transition., Su-Hyung Lee, Ela W Contreras Panta, David Gibbs, Yoonkyung Won, Jimin Min, Changqing Zhang, Joseph T Roland, Se-Hoon Hong, Yoojin Sohn, Evan Krystofiak, Bogun Jang, Lorenzo Ferri, Veena Sangwan, Jiannis Ragoussis, Sophie Camilleri-Broët, Joseph Caruso, Chira Chen-Tanyolac, Michael Strasser, Philippe Gascard, Thea D Tlsty, Sui Huang, Eunyoung Choi, and James R Goldenring

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Postvaccination Symptoms After a Fourth Dose of mRNA SARS-CoV-2 Vaccination in Patients With Inflammatory Bowel Disease., Yoo Jin Lee, Dalin Li, Angela Mujukian, Philip Debbas, Melissa Hampton, Emebet Mengesha, Susan Cheng, Joseph E Ebinger, Michael Chiorean, Donald Lum, Oriana M Damas, Jonathan Braun, Dermot P B McGovern, and Gil Y Melmed

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Growth phase estimation for abundant bacterial populations sampled longitudinally from human stool metagenomes., Joe J Lim, Christian Diener, James Wilson, Jacob J Valenzuela, Nitin S Baliga, and Sean M Gibbons

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Feasibility of circulating tumor DNA (ctDNA) to guide organ preservation in patients with node-negative rectal cancer undergoing neoadjuvant chemotherapy, excision, and observation in the phase II CCTG CO.28 trial, Jonathan M. Loree, Hagen F Kennecke, and See full list of authors in comments

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Clinical validation of contrast-enhanced ultrasound liver imaging reporting and data system in a prospective multinational study in North America and Europe., Andrej Lyshchik, Corinne E Wessner, Kristen Bradigan, John R Eisenbrey, Flemming Forsberg, Misung Yi, Scott W Keith, Yuko Kono, Stephanie R Wilson, Alexandra Medellin, Shuchi K Rodgers, Virginia Planz, Aya Kamaya, Lisa Finch, David Fetzer, Annalisa Berzigotti, Paul S Sidhu, and Fabio Piscaglia

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Evolution in the treatment of gastroesophageal reflux disease over the last century: from a crural-centered to a lower esophageal sphincter-centered approach and back., Emily M Mackay and Brian E Louie

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Obesity Modifies Clinical Outcomes of Right Ventricular Dysfunction., Janet I Ma, Emily K Zern, Juhi K Parekh, Ndidi Owunna, Nona Jiang, Dongyu Wang, Paula K Rambarat, Eugene Pomerantsev, Michael H Picard, and Jennifer E Ho

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A water-soluble alternative to simethicone for gastrointestinal endoscopy: Results of a clinical trial., Teri S Mallard, Sandra S Roswell, Evan P Sylvester, Cori L Ofstead, James M Scanlan, John J Brandabur, and Amarnath V Ramakrishnan

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Plasma phosphocreatine (PC) as a predictive biomarker for immune checkpoint inhibition in patients with refractory metastatic colorectal cancer (mCRC): Analysis of the CCTG CO.26 trial., Lucy Xiaolu Ma, Hagen F Kennecke, and See full list of authors in comments

Plasma arginine as a candidate predictive biomarker for response to immune checkpoint inhibition (ICI) in metastatic colorectal cancer (mCRC): Analysis of the CCTG CO.26 trial, LX Ma, H Kennecke, and See all authors in comments

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Disease-specific loss of microbial cross-feeding interactions in the human gut., Vanessa R Marcelino, Caitlin Welsh, Christian Diener, Emily L Gulliver, Emily L Rutten, Remy B Young, Edward M Giles, Sean M Gibbons, Chris Greening, and Samuel C Forster

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Disease-specific loss of microbial cross-feeding interactions in the human gut, Vanessa R. Marcelino, Caitlin Welsh, Christian Diener, Emily L. Gulliver, Emily L. Rutten, Remy B. Young, Edward M. Giles, Sean M Gibbons, Chris Greening, and Samuel C. Forster

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Diaphragmatic relaxing incisions for complex hiatal reconstruction: longer-term follow-up confirms safety, efficacy and rare complications., Sarah C McKay, Steven R DeMeester, Ahmed Sharata, Melissa L DeSouza, Daniel Davila Bradley, Kevin M Reavis, and Christy M Dunst

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Missed Opportunities: the Timing and Frequency of Screening Colonoscopy in Patients That Develop Esophageal Adenocarcinoma., Sarah C McKay, Melissa L DeSouza, Christy M Dunst, Kevin M Reavis, Daniel Davila Bradley, and Steven R DeMeester

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Missed Opportunities: the Timing and Frequency of Screening Colonoscopy in Patients That Develop Esophageal Adenocarcinoma., Sarah C McKay, Melissa L DeSouza, Christy M Dunst, Kevin M Reavis, Daniel Davila Bradley, and Steven R DeMeester

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Best Practices in Esophageal, Gastroduodenal, and Colonic Stenting., Renato Medas, Joel Ferreira-Silva, Mohit Girotra, Monique Barakat, James H Tabibian, and Eduardo Rodrigues-Pinto

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Multicenter International Study of the Consensus Immunoscore for the Prediction of Relapse and Survival in Early-Stage Colon Cancer., Bernhard Mlecnik, Alessandro Lugli, Gabriela Bindea, Florence Marliot, Carlo Bifulco, Jiun-Kae Jack Lee, Inti Zlobec, Tilman T Rau, Martin D Berger, Iris D Nagtegaal, Elisa Vink-Börger, Arndt Hartmann, Carol I Geppert, Julie Kolwelter, Susanne Merkel, Robert Grützmann, Marc Van den Eynde, Anne Jouret-Mourin, Alex Kartheuser, Daniel Léonard, Christophe Remue, Julia Wang, Prashant Bavi, Michael H A Roehrl, Pamela S Ohashi, Linh T Nguyen, SeongJun Han, Heather L MacGregor, Sara Hafezi-Bakhtiari, Bradly G Wouters, Giuseppe V Masucci, Emilia K Andersson, Eva Zavadova, Michal Vocka, Jan Spacek, Lubos Petruzelka, Bohuslav Konopasek, Pavel Dundr, Helena Skalova, Kristyna Nemejcova, Gerardo Botti, Fabiana Tatangelo, Paolo Delrio, Gennaro Ciliberto, Michele Maio, Luigi Laghi, Fabio Grizzi, Tessa Fredriksen, Bénédicte Buttard, Lucie Lafontaine, Pauline Maby, Amine Majdi, Assia Hijazi, Carine El Sissy, Amos Kirilovsky, Anne Berger, Christine Lagorce, Christopher Paustian, Carmen Ballesteros-Merino, Jeroen Dijkstra, Carlijn van de Water, Shannon van Lent-van Vliet, Nikki Knijn, Ana-Maria Mușină, Dragos-Viorel Scripcariu, Boryana Popivanova, Mingli Xu, Tomonobu Fujita, Shoichi Hazama, Nobuaki Suzuki, Hiroaki Nagano, Kiyotaka Okuno, Toshihiko Torigoe, Noriyuki Sato, Tomohisa Furuhata, Ichiro Takemasa, Prabhu Patel, Hemangini H Vora, Birva Shah, Jayendrakumar B Patel, Kruti N Rajvik, Shashank J Pandya, Shilin N Shukla, Yili Wang, Guanjun Zhang, Yutaka Kawakami, Francesco M Marincola, Paolo A Ascierto, Bernard A Fox, Franck Pagès, and Jérôme Galon

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Benefits and challenges in implementation of artificial intelligence in colonoscopy: World Endoscopy Organization position statement., Yuichi Mori, James E East, Cesare Hassan, Natalie Halvorsen, Tyler M Berzin, Michael Byrne, Daniel von Renteln, David G Hewett, Alessandro Repici, Mohan Ramchandani, Maryam Al Khatry, Shin-Ei Kudo, Pu Wang, Honggang Yu, Yutaka Saito, Masashi Misawa, Sravanthi Parasa, Carolina Ogawa Matsubayashi, Haruhiko Ogata, Hisao Tajiri, Nonthalee Pausawasdi, Evelien Dekker, Omer F Ahmad, Prateek Sharma, and Douglas K Rex

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Geographical region and clinical outcomes of patients with primary biliary cholangitis from Western Europe., Carla F Murillo Perez, Alessio Gerussi, Palak J Trivedi, Christophe Corpechot, Adriaan J van der Meer, Pier Maria Battezzati, Keith D Lindor, Frederik Nevens, Kris V Kowdley, Tony Bruns, Nora Cazzagon, Annarosa Floreani, Atsushi Tanaka, Xiong Ma, Andrew L Mason, Aliya Gulamhusein, Cyriel Y Ponsioen, Marco Carbone, Ana Lleo, Marlyn J Mayo, George N Dalekos, Nikolaos K Gatselis, Douglas Thorburn, Xavier Verhelst, Albert Parés, Harry L A Janssen, Gideon M Hirschfield, Bettina E Hansen, Pietro Invernizzi, Willem J Lammers, and GLOBAL PBC Study Group

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Mirizzi Syndrome in the Setting of Hemorrhagic Cholecystitis., Priscilla Natcher and Danielle Hayes

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Transperitoneal Versus Retroperitoneal Robotic-Assisted Partial Nephrectomy in Patients with Obesity., Kennedy E Okhawere, Jordan Miller Rich, Alp Tuna Beksac, Laura Zuluaga, Indu Saini, Burak Ucpinar, Joshua Levieddin, Iretiayo T Joel, Anthony Deluxe, Michael D Stifelman, Simone Crivellaro, Ronney Abaza, Daniel D Eun, Akshay Bhandari, Ashok K Hemal, James Porter, Ahmed Mansour, Phillip M Pierorazio, Osama Zaytoun, and Ketan K Badani