The Digestive Health Institute is a network of highly trained doctors and surgeons who treat disorders of the gastrointestinal (GI) tract, as well as the liver, gallbladder and pancreas. As it becomes increasingly complex to treat digestive diseases and GI cancer, optimizing care relies more on the close collaboration of experts from across disciplines.

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Submissions from 2019

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Innovative use of mesh bolster for adult Morgagni hernia repair., Nabiel Azar, Robert Azar, Katie Robertson, and Priya Gupta

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Minimally invasive sigmoidectomy for diverticular disease decreases inpatient opioid use: Results of a propensity score-matched study., Amir Bastawrous, I-Fan Shih, Yanli Li, and Robert K Cleary

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The utility of CT scan for the diagnostic evaluation of acute abdominal pain., Timothy Bax, Matthew Macha, and John Mayberry

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Magnetic Sphincter Augmentation Superior to Proton Pump Inhibitors for Regurgitation in a 1-year Randomized Trial., Reginald Bell, John Lipham, Brian E Louie, Valerie Williams, James Luketich, Michael Hill, William Richards, Christy Dunst, Dan Lister, Lauren McDowell-Jacobs, Patrick Reardon, Karen Woods, Jon Gould, F Paul Buckley, Shanu Kothari, Leena Khaitan, C Daniel Smith, Adrian Park, Christopher Smith, Garth Jacobsen, Ghulam Abbas, and Philip Katz

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Effects of Age and Sex of on Response to Ursodeoxycholic Acid and Transplant-free Survival in Patients With Primary Biliary Cholangitis., Angela C Cheung, Willem J Lammers, Carla F Murillo Perez, Henk R van Buuren, Aliya Gulamhusein, Palak J Trivedi, Konstantinos N Lazaridis, Cyriel Y Ponsioen, Annarosa Floreani, Gideon M Hirschfield, Christophe Corpechot, Marlyn J Mayo, Pietro Invernizzi, Pier Maria Battezzati, Albert Parés, Frederik Nevens, Douglas Thorburn, Andrew L Mason, Marco Carbone, Kris V Kowdley, Tony Bruns, George N Dalekos, Nikolaos K Gatselis, Xavier Verhelst, Keith D Lindor, Ana Lleo, Raoul Poupon, Harry L Janssen, and Bettina E Hansen

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Commentary: Adherence with a low-FODMAP diet in irritable bowel syndrome: are eating disorders the missing link?, Bruno P Chumpitazi, Ligia Alfaro-Cruz, Jasmine K Zia, Robert J Shulman, and Margaret M Heitkemper

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Dieulafoy Lesion: An Unusual Cause of Excessive Gastric Bleeding in a Neonate., Alison Kirse Coit, Uma Pisharody, and Michael Kamitsuka

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Outcomes following early versus delayed cholecystectomy performed for acute cholangitis., Andrew Discolo, Shelby Reiter, Bryce French, Danielle Hayes, Gary Lucas, Lancy Tan, James M Scanlan, and Ryan Martinez

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Factors Associated With Progression and Outcomes of Early-stage Primary Biliary Cholangitis., Nikolaos K Gatselis, Jorn C Goet, Kalliopi Zachou, Willem J Lammers, Harry L A Janssen, Gideon Hirschfield, Christophe Corpechot, Keith D Lindor, Pietro Invernizzi, Marlyn J Mayo, Pier Maria Battezzati, Annarosa Floreani, Albert Pares, Vasiliki Lygoura, Frederik Nevens, Andrew L Mason, Kris V Kowdley, Cyriel Y Ponsioen, Tony Bruns, Douglas Thorburn, Xavier Verhelst, Maren H Harms, Henk R van Buuren, Bettina E Hansen, and George N Dalekos

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A Pilot Genome-Wide Analysis Study Identifies Loci Associated With Response to Obeticholic Acid in Patients With NASH., Samer Gawrieh, Xiuqing Guo, Jingyi Tan, Marie Lauzon, Kent D Taylor, Rohit Loomba, Oscar W Cummings, Sreekumar Pillai, Pallav Bhatnagar, Kris V Kowdley, Katherine Yates, Laura A Wilson, Yii-Der Ida Chen, Jerome I Rotter, and Naga Chalasani

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Histologic Findings of Advanced Fibrosis and Cirrhosis in Patients With Nonalcoholic Fatty Liver Disease Who Have Normal Aminotransferase Levels., Samer Gawrieh, Laura A Wilson, Oscar W Cummings, Jeanne M Clark, Rohit Loomba, Bilal Hameed, Manal F Abdelmalek, Srinivasan Dasarathy, Brent A Neuschwander-Tetri, Kris V Kowdley, David Kleiner, Edward Doo, James Tonascia, Arun Sanyal, and Naga Chalasani

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Alterations in Phosphorylation of Hepatocyte Ribosomal Protein S6 Control Plasmodium Liver Stage Infection., Elizabeth K K Glennon, Laura S Austin, Nadia Arang, Heather S Kain, Fred D Mast, Kamalakannan Vijayan, John D Aitchison, Stefan H I Kappe, and Alexis Kaushansky

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Epidemiology of Colorectal Cancer in Average Risk Adults 20-39 Years of Age: A Population-Based National Study., Michael Glover, Emad Mansoor, Muhammed Panhwar, Sravanthi Parasa, and Gregory S Cooper

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Blockade of fibroblast activation protein in combination with radiation treatment in murine models of pancreatic adenocarcinoma., Andrew J Gunderson, Tomoko Yamazaki, Kayla McCarty, Michaela Phillips, Alejandro F Alice, Shelly Bambina, Lauren Zebertavage, David Friedman, Benjamin Cottam, Pippa Newell, Michael J. Gough, Marka R Crittenden, Pieter Van der Veken, and Kristina H Young

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Endoscopic Ultrasound Assessment of Pancreatic Duct Diameter Predicts Neuroendocrine Tumors and Other Pancreas Masses., Nikhil Gupta, Ravi Kankotia, Ara Sahakian, Preeth Jayaram, Alex Shindel, Elizabeth Dong, Paul Korc, Mohamad Eloubeidi, and James Buxbaum

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The Value of Quick Sepsis-Related Organ Failure Assessment Scores in Patients With Acute Pancreatitis Who Present to Emergency Departments: A Three-Year Cohort Study., Alexander Hallac, Nishant Puri, David Applebury, Kurt Myers, Parag Dhumal, Ashish Thatte, and Wichit Srikureja

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Number needed to treat with ursodeoxycholic acid therapy to prevent liver transplantation or death in primary biliary cholangitis., Maren H Harms, Rozanne C de Veer, Willem J Lammers, Christophe Corpechot, Douglas Thorburn, Harry L A Janssen, Keith D Lindor, Palak J Trivedi, Gideon M Hirschfield, Albert Pares, Annarosa Floreani, Marlyn J Mayo, Pietro Invernizzi, Pier Maria Battezzati, Frederik Nevens, Cyriel Y Ponsioen, Andrew L Mason, Kris V Kowdley, Bettina E Hansen, Henk R van Buuren, and Adriaan J van der Meer

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Ursodeoxycholic acid therapy and liver transplant-free survival in patients with primary biliary cholangitis., Maren H Harms, Henk R van Buuren, Christophe Corpechot, Douglas Thorburn, Harry L A Janssen, Keith D Lindor, Gideon M Hirschfield, Albert Parés, Annarosa Floreani, Marlyn J Mayo, Pietro Invernizzi, Pier Maria Battezzati, Frederik Nevens, Cyriel Y Ponsioen, Andrew L Mason, Kris V Kowdley, Willem J Lammers, Bettina E Hansen, and Adriaan J van der Meer

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Healthy Weight Initiative, Stephanie Horlton (Presenter), Kathy Schwab, Lindsey Coppel, Ruth Fischer-Wright, and Mary Potter

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Octogenarians exhibit quality of life improvement but increased morbidity after paraesophageal hernia repair., Anahita D Jalilvand, Edward L Jones, Sara E Martin Del Campo, and Kyle A Perry

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Randomized Phase II Study Evaluating Palbociclib in Addition to Letrozole as Neoadjuvant Therapy in Estrogen Receptor-Positive Early Breast Cancer: PALLET Trial., Stephen Johnston, Shannon Puhalla, Duncan Wheatley, Alistair Ring, Peter Barry, Chris Holcombe, Jean Francois Boileau, Louise Provencher, André Robidoux, Mothaffar Rimawi, Stuart A McIntosh, Ibrahim Shalaby, Robert C Stein, Michael Thirlwell, David Dolling, James Morden, Claire Snowdon, Sophie Perry, Chester Cornman, Leona M Batten, Lisa K Jeffs, Andrew Dodson, Vera Martins, Arjun Modi, C Kent Osborne, Katherine L Pogue-Geile, Maggie Chon U Cheang, Norman Wolmark, Thomas B Julian, Kate Fisher, Mairead MacKenzie, Maggie Wilcox, Cynthia Huang Bartlett, Maria Koehler, Mitch Dowsett, Judith M Bliss, and Samuel A Jacobs

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Safety and Efficacy of Durvalumab and Tremelimumab Alone or in Combination in Patients with Advanced Gastric and Gastroesophageal Junction Adenocarcinoma., Ronan J Kelly, Jeeyun Lee, Yung-Jue Bang, Khaldoun Almhanna, Mariela Blum Murphy, Daniel V T Catenacci, Hyun Cheol Chung, Zev A Wainberg, Michael K Gibson, Keun-Wook Lee, Johanna C Bendell, Crystal S Denlinger, Cheng Ean Chee, Takeshi Omori, Rom Leidner, Heinz-Josef Lenz, Yee Chao, Marlon C Rebelatto, Philip Brohawn, Peng He, Jennifer McDevitt, Siddharth Sheth, Judson M Englert, and Geoffrey Y Ku

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Characterization of patients with both alcoholic and nonalcoholic fatty liver disease in a large United States cohort., George Khoudari, Amandeep Singh, Mazen Noureddin, Danielle Fritze, Rocio Lopez, Imad Asaad, Eric Lawitz, Fred Poordad, Kris V Kowdley, and Naim Alkhouri

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Radioembolization with Yttrium-90 Microspheres for the Treatment of Liver Metastases of Pancreatic Adenocarcinoma: A Multicenter Analysis., Alexander Y Kim, Shelby Frantz, Jayson Brower, and Nabeel Akhter

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Association of Histologic Disease Activity With Progression of Nonalcoholic Fatty Liver Disease., David E Kleiner, Elizabeth M Brunt, Laura A Wilson, Cynthia Behling, Cynthia Guy, Melissa Contos, Oscar Cummings, Matthew Yeh, Ryan Gill, Naga Chalasani, Brent A Neuschwander-Tetri, Anna Mae Diehl, Srinivasan Dasarathy, Norah Terrault, Kris V Kowdley, Rohit Loomba, Patricia Belt, James Tonascia, Joel E Lavine, and Arun J Sanyal

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ACG Clinical Guideline: Hereditary Hemochromatosis., Kris V Kowdley, Kyle E Brown, Joseph Ahn, and Vinay Sundaram

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ACG Clinical Guideline: Hereditary Hemochromatosis., Kris V Kowdley, Kyle E Brown, Joseph Ahn, and Vinay Sundaram

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Short-Term and Long-Term Outcomes of Paraesophageal Hernia Repair., Anne-Sophie Laliberte and Brian E Louie

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Efficacy and safety of ruzasvir 60 mg and uprifosbuvir 450 mg for 12 weeks in adults with chronic hepatitis C virus genotype 1, 2, 3, 4 or 6 infection., Eric Lawitz, Fred Poordad, Leah J Anderson, Michelle Vesay, Michelle M Kelly, Hong Liu, Wei Gao, Doreen Fernsler, Ernest Asante-Appiah, Michael N Robertson, George J Hanna, Eliav Barr, Joan Butterton, Kris V Kowdley, Tarek Hassanein, Amandeep Sahota, Stuart C Gordon, and Wendy W Yeh

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Underestimation of Liver Transplantation for Alcoholic Hepatitis in the National Transplant Database., Brian P Lee, Gene Y Im, John P Rice, Ethan Weinberg, Christine Hsu, Oren K Fix, George Therapondos, Hyosun Han, David W Victor, Sheila Eswaran, Haripriya Maddur, and Norah A Terrault

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Model to Calculate Harms and Benefits of Early vs Delayed Liver Transplantation for Patients with Alcohol-Associated Hepatitis., Brian P Lee, Sumeyye Samur, Ozden O Dalgic, Emily D Bethea, Michael R Lucey, Ethan Weinberg, Christine Hsu, Mary E Rinella, Gene Y Im, Oren K Fix, George Therapondos, Hyosun Han, David W Victor, Michael D Voigt, Sheila Eswaran, Norah A Terrault, and Jagpreet Chhatwal

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Duration of Oxaliplatin-Containing Adjuvant Therapy for Stage III Colon Cancer: ASCO Clinical Practice Guideline., Christopher Lieu, Erin B Kennedy, Emily Bergsland, Jordan Berlin, Thomas J George, Sharlene Gill, Philip J Gold, Alex Hantel, Lee Jones, Najjia Mahmoud, Jeffrey Meyerhardt, Arden M Morris, Erika Ruíz-García, Y Nancy You, and Nancy Baxter

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Objective Evidence of Reflux Control After Magnetic Sphincter Augmentation: One Year Results From a Post Approval Study., Brian Louie, C Daniel Smith, Christopher C Smith, Reginald C W Bell, George Kevin Gillian, Jeffrey S Mandel, Kyle A Perry, Walter Kurt Birkenhagen, Paul A Taiganides, Christy M Dunst, Howard M McCollister, John C Lipham, Leena K Khaitan, Shawn T Tsuda, Blair A Jobe, Shanu N Kothari, and Jon C Gould

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Precision Medicine in Pancreatic Disease-Knowledge Gaps and Research Opportunities: Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop., Mark E Lowe, Dana K Andersen, Richard M Caprioli, Jyoti Choudhary, Zobeida Cruz-Monserrate, Anil K Dasyam, Christopher E Forsmark, Fred S Gorelick, Joe W Gray, Mark Haupt, Kimberly A Kelly, Kenneth P Olive, Sylvia K Plevritis, Noa Rappaport, Holger R Roth, Hanno Steen, S Joshua Swamidass, Temel Tirkes, Aliye Uc, Kirill Veselkov, David C Whitcomb, and Aida Habtezion

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Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal Cancer., Winifred Lo, Maria Parkhurst, Paul F Robbins, Eric Tran, Yong-Chen Lu, Li Jia, Jared J Gartner, Anna Pasetto, Drew Deniger, Parisa Malekzadeh, Thomas E Shelton, Todd Prickett, Satyajit Ray, Scott Kivitz, Biman C Paria, Isaac Kriley, David S Schrump, and Steven A Rosenberg

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Surgical and anesthetic management for hepatectomy in two pediatric patients with trisomy 18, pulmonary hypertension, and hepatoblastoma., Donald J Lucas, Jeremy Rubinstein, Ankush Gosain, Greg Tiao, Tim Head, J Nick Pratap, Regan Williams, Sara Helmig, James Geller, Max Langham, and Angela Trobaugh-Lotrario

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Current perspectives into the evaluation and management of hepatitis B: a review., Vignan Manne, Eric Gochanour, and Kris V Kowdley

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Obeticholic acid in primary biliary cholangitis: where we stand., Vignan Manne and Kris V Kowdley

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Incorporating a Detailed Case Log System to Standardize Robotic Colon and Rectal Surgery Resident Training and Performance Evaluation., Rachel Martin, June Hsu, Mark K Soliman, Amir Bastawrous, and Robert K Cleary

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CLINICAL PRACTICE GUIDELINES FOR THE PERIOPERATIVE NUTRITION, METABOLIC, AND NONSURGICAL SUPPORT OF PATIENTS UNDERGOING BARIATRIC PROCEDURES - 2019 UPDATE: COSPONSORED BY AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS/AMERICAN COLLEGE OF ENDOCRINOLOGY, THE OBESITY SOCIETY, AMERICAN SOCIETY FOR METABOLIC & BARIATRIC SURGERY, OBESITY MEDICINE ASSOCIATION, AND AMERICAN SOCIETY OF ANESTHESIOLOGISTS., Jeffrey I Mechanick, Caroline Apovian, Stacy Brethauer, W Timothy Garvey, Aaron M Joffe, Julie Kim, Robert F Kushner, Richard Lindquist, Rachel Pessah-Pollack, Jennifer Seger, Richard Urman, Stephanie Adams, John B Cleek, Riccardo Correa, M Kathleen Figaro, Karen Flanders, Jayleen Grams, Daniel L Hurley, Shanu Kothari, Michael V Seger, and Christopher D Still

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Real-World Characterization of Dimethyl Fumarate-Related Gastrointestinal Events in Multiple Sclerosis: Management Strategies to Improve Persistence on Treatment and Patient Outcomes., Jinny Min, Stanley Cohan, Enrique Alvarez, Jacob Sloane, J Theodore Phillips, Anneke van der Walt, Irene Koulinska, Fang Fang, Catherine Miller, and Andrew Chan

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Epidemiologic features of a large hepatitis C cohort evaluated in a major health system in the western United States., Nizar A Mukhtar, Erik M Ness, Manan Jhaveri, Oren K Fix, Marquis Hart, Christopher Dale, Cheryl Pratt, and Kris V Kowdley

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Development and validation of a web-based electronic application in managing antithrombotic agents in patients undergoing GI endoscopy., Venkat Nutalapati, Krishna Teja Tokala, Madhav Desai, Vijay Kanakadandi, Mojtaba Olyaee, Sravanthi Parasa, and Amit Rastogi

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Estimating neoplasia detection rate (NDR) in patients with Barrett's oesophagus based on index endoscopy: a systematic review and meta-analysis., Sravanthi Parasa, Madhav Desai, Anusha Vittal, Viveksandeep T Chandrasekar, Asad Pervez, Kevin F Kennedy, Neil Gupta, Nicholas J Shaheen, and Prateek Sharma

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Unique Neoantigens Arise from Somatic Mutations in Patients with Gastrointestinal Cancers., Maria R Parkhurst, Paul F Robbins, Eric Tran, Todd D Prickett, Jared J Gartner, Li Jia, Gabriel Ivey, Yong F Li, Mona El-Gamil, Almin Lalani, Jessica S Crystal, Abraham Sachs, Eric Groh, Satyajit Ray, Lien T Ngo, Scott Kivitz, Anna Pasetto, Rami Yossef, Frank J Lowery, Stephanie L Goff, Winifred Lo, Gal Cafri, Drew C Deniger, Parisa Malekzadeh, Mojgan Ahmadzadeh, John R Wunderlich, Robert P T Somerville, and Steven A Rosenberg

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A library of human gut bacterial isolates paired with longitudinal multiomics data enables mechanistic microbiome research., M Poyet, M Groussin, S M Gibbons, J Avila-Pacheco, X Jiang, S M Kearney, A R Perrotta, B Berdy, S Zhao, T D Lieberman, P K Swanson, M Smith, S Roesemann, J E Alexander, S A Rich, J Livny, H Vlamakis, C Clish, K Bullock, A Deik, J Scott, K A Pierce, R J Xavier, and E J Alm

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Early experience with cap-assisted endoscopic pancreatic necrosectomy: A technique to enhance safe tissue extraction and decrease interventions., Nishant Puri, Alexander Hallac, and Wichit Srikureja

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Laparoscopic anti-reflux procedures with hepatic shoulder technique in the surgical management of large hiatal hernias and paraesophageal hernias: a follow-up study., Philippe J Quilici, Alexander Tovar, Jung Li, and Tiffany Herrera

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Treatment of patients with HIV or hepatitis C by pharmacist clinicians in a patient-centered medical home., Keenan L Ryan, Bernadette Jakeman, Jessica Conklin, Larry J Pineda, Paulina Deming, and Renee-Claude Mercier

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Treatment of patients with HIV or hepatitis C by pharmacist clinicians in a patient-centered medical home., Keenan L Ryan, Bernadette Jakeman, Jessica Conklin, Larry J Pineda, Paulina Deming, and Renee-Claude Mercier

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Apixaban-induced haematoma causing small bowel intussusception., Ariel P Santos, Jennifer M Rodriguez, and Grace Berry

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Apixaban-induced haematoma causing small bowel intussusception., Ariel P Santos, Jennifer M Rodriguez, and Grace Berry

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Role of the Nutrition Support Clinician on a Hospital Bioethics Committee., Denise Baird Schwartz, Karen Pavic-Zabinski, and Katherine Tull

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Pediatric cholestatic liver disease: Successful transition of care., Praveen Kc Selvakumar, Vera Hupertz, Naveen Mittal, Kris V Kowdley, and Naim Alkhouri

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Mechanisms and Treatments of Pruritus in Primary Biliary Cholangitis., Raj A Shah and Kris V Kowdley

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Serum ferritin as a biomarker for NAFLD: ready for prime time?, Raj A Shah and Kris V Kowdley

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Developing Quality Metrics For Upper Endoscopy., Prateek Sharma, Sravanthi Parasa, and Nicholas Shaheen

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Use of a report card to evaluate outcomes of achalasia surgery: beyond the Eckardt score., Ealaf Shemmeri, Ralph W Aye, Alexander S Farivar, Adam J Bograd, and Brian E Louie

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Trifluridine/tipiracil (FTD/TPI) in patients (pts) aged ≥65 years with metastatic gastric/gastroesophageal junction cancer (mGC/mGEJC): Subgroup analysis from TAGS., Kohei Shitara, Toshihiko Doi, Hisashi Hosaka, Peter C. Thuss-Patience, Armando Santoro, Paula Jiménez-Fonseca, Federico Longo, Ozgur Ozyilkan, Irfan Cicin, David Park, Mohamedtaki Abdulaziz Tejani, Aziz Zaanan, Domenico Bilancia, Carles Pericay, Mustafa Ozguroglu, Maria Alsina, Lukas Makris, Sandra McGuigan, and David H. Ilson

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Compassionate use of cefiderocol in the treatment of an intraabdominal infection due to multidrug resistant Pseudomonas aeruginosa: A case report., Ryan W Stevens and Megan Clancy

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The nonsteroidal FXR agonist cilofexor (GS-9674) improves markers of cholestasis and liver injury in patients with PSC., Michael Trauner, Aliya Gulamhusein, Bilal Hameed, Stephen Caldwell, Mitchell L Shiffman, Charles Landis, Bertus Eksteen, Kosh Agarwal, Andrew Muir, Simon Rushbrook, Xiaomin Lu, Jun Xu, Jen-Chieh Chuang, Andrew N Billin, Chuhan Chung, Georgia Li, G Mani Subramanian, Robert P Myers, Christopher L Bowlus, and Kris V Kowdley

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The Immune Microenvironment Impacts Survival in Western Patients with Gastric Adenocarcinoma., Abhineet Uppal, Ahmed N Dehal, Shu-Ching Chang, Dany Barrak, Yalda Naeini, John R Jalas, and Anton J Bilchik

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Duodenal GI stromal tumors: Is radical resection necessary?, Abhineet Uppal, Mansen Wang, Trevan D Fischer, and Melanie Goldfarb

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Winning the Battle and the War Against C. difficile, Emily Villegas

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A Simple Measure of Hepatocellular Carcinoma Burden Predicts Tumor Recurrence after Liver Transplantation: The RH-IML Classification., Philip Vutien, Jennifer Dodge, Kiran M Bambha, Eric M Nordstrom, Jane Gralla, Kristen Campbell, Claire Levek, Trevor Nydam, Oren Fix, George Ioannou, and Scott W Biggins

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A Simple Measure of Hepatocellular Carcinoma Burden Predicts Tumor Recurrence After Liver Transplantation: The Recurrent Hepatocellular Carcinoma-Initial, Maximum, Last Classification., Philip Vutien, Jennifer Dodge, Kiran M Bambha, Eric M Nordstrom, Jane Gralla, Kristen Campbell, Claire Levek, Trevor Nydam, Oren K Fix, George Ioannou, and Scott W Biggins

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Mechanisms of Weight Loss After Sleeve Gastrectomy and Adjustable Gastric Banding: Far More Than Just Restriction., Yanmin Wang, Xiaomei Guo, Xiao Lu, Samer G Mattar, and Ghassan Kassab

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Can Impedance-pH Testing on Medications Reliably Identify Patients with GERD as Defined by Pathologic Esophageal Acid Exposure off Medications?, Marc A Ward, Christy M Dunst, Matthew E Glasgow, Ezra N Teitelbaum, Walaa F Abdelmoaty, Kevin M Reavis, Lee L Swanstrӧm, and Steven R DeMeester

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Laparoscopic vagal nerve blocking device explantation: case series and report of operative technique., Tarin C Worrest, Bruce M Wolfe, Samer G Mattar, and Erin W Gilbert

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Diagnosis and Management of Primary Biliary Cholangitis., Zobair M Younossi, David Bernstein, Mitchell L Shiffman, Paul Kwo, W Ray Kim, Kris V Kowdley, and Ira M Jacobson

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Obeticholic acid for the treatment of non-alcoholic steatohepatitis: interim analysis from a multicentre, randomised, placebo-controlled phase 3 trial., Zobair M Younossi, Vlad Ratziu, Rohit Loomba, Mary Rinella, Quentin M Anstee, Zachary Goodman, Pierre Bedossa, Andreas Geier, Susanne Beckebaum, Philip N Newsome, David Sheridan, Muhammad Y Sheikh, James Trotter, Whitfield Knapple, Eric Lawitz, Manal F Abdelmalek, Kris V Kowdley, Aldo J Montano-Loza, Jerome Boursier, Philippe Mathurin, Elisabetta Bugianesi, Giuseppe Mazzella, Antonio Olveira, Helena Cortez-Pinto, Isabel Graupera, David Orr, Lise Lotte Gluud, Jean-Francois Dufour, David Shapiro, Jason Campagna, Luna Zaru, Leigh MacConell, Reshma Shringarpure, Stephen Harrison, and Arun J Sanyal

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Obeticholic acid for the treatment of non-alcoholic steatohepatitis: interim analysis from a multicentre, randomised, placebo-controlled phase 3 trial., Zobair M Younossi, Vlad Ratziu, Rohit Loomba, Mary Rinella, Quentin M Anstee, Zachary Goodman, Pierre Bedossa, Andreas Geier, Susanne Beckebaum, Philip N Newsome, David Sheridan, Muhammad Y Sheikh, James Trotter, Whitfield Knapple, Eric Lawitz, Manal F Abdelmalek, Kris V Kowdley, Aldo J Montano-Loza, Jerome Boursier, Philippe Mathurin, Elisabetta Bugianesi, Giuseppe Mazzella, Antonio Olveira, Helena Cortez-Pinto, Isabel Graupera, David Orr, Lise Lotte Gluud, Jean-Francois Dufour, David Shapiro, Jason Campagna, Luna Zaru, Leigh MacConell, Reshma Shringarpure, Stephen Harrison, and Arun J Sanyal

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Adaptive Evolution within Gut Microbiomes of Healthy People., Shijie Zhao, Tami D Lieberman, Mathilde Poyet, Kathryn M Kauffman, Sean M Gibbons, Mathieu Groussin, Ramnik J Xavier, and Eric J Alm

Submissions from 2018

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A research agenda for curing chronic hepatitis B virus infection., Harvey Alter, Timothy Block, Nathaniel Brown, Alan Brownstein, Carol Brosgart, Kyong-Mi Chang, Pei-Jer Chen, Francis V Chisari, Chari Cohen, Hashem El-Serag, Jordan Feld, Robert Gish, Jeffrey Glenn, Tim Greten, Haitao Guo, Ju-Tao Guo, Yujin Hoshida, Jianming Hu, Kris V Kowdley, Wenhui Li, Jake Liang, Stephan Locarnini, Anna S Lok, William Mason, Brian McMahon, Anand Mehta, Robert Perrillo, Peter Revill, Charles M Rice, JoAnn Rinaudo, Raymond Schinazi, Christoph Seeger, Kirty Shetty, John Tavis, and Fabien Zoulim

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Efficacy of Glecaprevir/Pibrentasvir for 8 or 12 Weeks in Patients With Hepatitis C Virus Genotype 2, 4, 5, or 6 Infection Without Cirrhosis., Tarik Asselah, Kris V Kowdley, Neddie Zadeikis, Stanley Wang, Tarek Hassanein, Yves Horsmans, Massimo Colombo, Filipe Calinas, Humberto Aguilar, Victor de Ledinghen, Parvez S Mantry, Christophe Hezode, Rui Tato Marinho, Kosh Agarwal, Frederik Nevens, Magdy Elkhashab, Jens Kort, Ran Liu, Teresa I Ng, Preethi Krishnan, Chih-Wei Lin, and Federico J Mensa

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Discussion of "Sarcopenia is not associated with morbidity, mortality, or recurrence after esophagectomy for cancer"., Ralph W. Aye MD

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Haptoglobin 2 Allele is Associated With Histologic Response to Vitamin E in Subjects With Nonalcoholic Steatohepatitis., Bubu A Banini, Sophie C Cazanave, Katherine P Yates, Amon Asgharpour, Robert Vincent, Faridoddin Mirshahi, Peter Le, Melissa J Contos, James Tonascia, Naga P Chalasani, Kris V Kowdley, Arthur J McCullough, Cynthia A Behling, Jeffrey B Schwimmer, Joel E Lavine, and Arun J Sanyal

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Hepatic R2* is more strongly associated with proton density fat fraction than histologic liver iron scores in patients with nonalcoholic fatty liver disease., Mustafa R Bashir, Tanya Wolfson, Anthony C Gamst, Kathryn J Fowler, Michael Ohliger, Shetal N Shah, Adina Alazraki, Andrew T Trout, Cynthia Behling, Daniela S Allende, Rohit Loomba, Arun Sanyal, Jeffrey Schwimmer, Joel E Lavine, Wei Shen, James Tonascia, Mark L Van Natta, Adrija Mamidipalli, Jonathan Hooker, Kris V Kowdley, Michael S Middleton, and Claude B Sirlin

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A Hill Gastropexy Combined with Nissen Fundoplication Appears Equivalent to a Collis-Nissen in the Management of Short Esophagus., Oliver C Bellevue, Brian E Louie, Zeljka Jutric, Alexander S Farivar, and Ralph W Aye

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Laparoscopic magnetic sphincter augmentation versus double-dose proton pump inhibitors for management of moderate-to-severe regurgitation in GERD: a randomized controlled trial., R C Bell, J C Lipham, B E Louie, V A Williams, J D Luketich, M A Hill, W O Richards, C M Dunst, D G Lister, L E McDowell-Jacobs, P R Reardon, K L Woods, J C Gould, F Buckley, S N Kothari, L Khaitan, C D Smith, A Park, C C Smith, G R Jacobsen, G Abbas, and P O Katz

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Research priorities for the discovery of a cure for chronic hepatitis B: Report of a workshop., Timothy M Block, Harvey Alter, Nathaniel Brown, Alan Brownstein, Carol Brosgart, Kyong-Mi Chang, Pei-Jer Chen, Chari Cohen, Hashem El-Serag, Jordan Feld, Robert Gish, Jeffrey Glenn, Tim F Greten, Juo-Tao Guo, Yujin Hoshida, Kris V Kowdley, Wenhui Li, Anna S Lok, Brian McMahon, Anand Mehta, Robert Perrillo, Charles M Rice, JoAnn Rinaudo, Raymond F Schinazi, and Kirti Shetty

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Sofosbuvir, Velpatasvir, and Voxilaprevir for Treatment of Recurrent Hepatitis C Virus Infection After Liver Transplantation., Maria G Cardona-Gonzalez, Jason D Goldman, Lawrence Narayan, Diana M Brainard, and Kris V Kowdley

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Antibiotic Utilization Before Endourological Surgery for Urolithiasis: Endourological Society Survey Results., Evan C Carlos, Ramy F Youssef, Adam G Kaplan, Daniel A Wollin, Brent B Winship, Brian H Eisner, Roger L Sur, Glenn M Preminger, and Michael E Lipkin

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Relationship Between Three Commonly Used Non-invasive Fibrosis Biomarkers and Improvement in Fibrosis Stage in Patients With NASH., Naga Chalasani, Manal F Abdelmalek, Rohit Loomba, Kris V Kowdley, Arthur J McCullough, Srinivasan Dasarathy, Brent A Neuschwander-Tetri, Norah Terrault, Beatrice Ferguson, Reshma Shringarpure, David Shapiro, and Arun J Sanyal

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Histopathology of locally advanced colorectal carcinoma, with emphasis on tumor invasion of adherent peritoneal membranes., Jey-Hsin Chen

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Hepatitis C virus re-treatment in the era of direct-acting antivirals: projections in the USA., J Chhatwal, Q Chen, T Ayer, E D Bethea, F Kanwal, K V Kowdley, X Wang, M S Roberts, and S C Gordon

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Rates of Prevalent Colorectal Cancer Occurrence in Persons 75 Years of Age and Older: A Population-Based National Study., Vijit Chouhan, Emad Mansoor, Sravanthi Parasa, and Gregory S Cooper

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Intracorporeal versus extracorporeal anastomosis for minimally invasive right colectomy: A multi-center propensity score-matched comparison of outcomes., Robert K Cleary, Andrew Kassir, Craig S Johnson, Amir L Bastawrous, Mark K Soliman, Daryl S Marx, Luca Giordano, Tobi J Reidy, Eduardo Parra-Davila, Vincent J Obias, Joseph C Carmichael, Darren Pollock, and Alessio Pigazzi

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Prediagnostic circulating markers of inflammation and risk of oesophageal adenocarcinoma: a study within the National Cancer Institute Cohort Consortium., Michael B Cook, Matthew J Barnett, Cathryn H Bock, Amanda J Cross, Phyllis J Goodman, Gary E Goodman, Christopher A Haiman, Kay-Tee Khaw, Marjorie L McCullough, Christine C Newton, Marie-Christine Boutron-Ruault, Eiliv Lund, Martin Rutegård, Mark D Thornquist, Michael Spriggs, Carol Giffen, Neal D Freedman, Troy Kemp, Candyce H Kroenke, Loïc Le Marchand, Jin Young Park, Michael Simon, Lynne R Wilkens, Ligia Pinto, Allan Hildesheim, and Peter T Campbell

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Current Imaging Modalities Understage One-Third of Patients with Stage I Rectal Cancer: Implications for Treatment Selection., Ahmed Dehal, Amanda N Graff-Baker, Brooke Vuong, Daniel Nelson, Shu-Ching Chang, Melanie Goldfarb, and Anton J Bilchik

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Neoadjuvant Chemotherapy Improves Survival in Patients with Clinical T4b Colon Cancer., Ahmed N Dehal, Amanda N Graff-Baker, Brooke Vuong, Trevan Fischer, Samuel J Klempner, Shu-Ching Chang, Gary Grunkemeier, Anton J Bilchik, and Melanie Goldfarb

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Increasing prevalence of high-grade dysplasia and adenocarcinoma on index endoscopy in Barrett's esophagus over the past 2 decades: data from a multicenter U.S. consortium., Madhav Desai, David A Lieberman, Kevin F Kennedy, Nour Hamade, Prashanthi Thota, Sravanthi Parasa, Venkat Subhash Gorrepati, Ajay Bansal, Neil Gupta, Srinivas Gaddam, Patrick E Young, Sharad Mathur, Fouad J Moawad, Brooks D Cash, Richard Sampliner, John J Vargo, Gary W Falk, and Prateek Sharma

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The Effect of Formal Robotic Residency Training on the Adoption of Minimally Invasive Surgery by Young Colorectal Surgeons., David E Disbrow, Stephanie M Pannell, Beth-Ann Shanker, Jeremy Albright, Juan Wu, Amir Bastawrous, Mark Soliman, Jane Ferraro, and Robert K Cleary

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Macrophage-derived IL-1β/NF-κB signaling mediates parenteral nutrition-associated cholestasis., Karim C El Kasmi, Padade M Vue, Aimee L Anderson, Michael W Devereaux, Swati Ghosh, Natarajan Balasubramaniyan, Sophie A Fillon, Carola Dahrenmoeller, Ayed Allawzi, Crystal Woods, Sarah McKenna, Clyde J Wright, Linda Johnson, Angelo D'Alessandro, Julie A Reisz, Eva Nozik-Grayck, Frederick J Suchy, and Ronald J Sokol

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American Society for Metabolic and Bariatric Surgery estimation of metabolic and bariatric procedures performed in the United States in 2016., Wayne J English, Eric J DeMaria, Stacy A Brethauer, Samer G Mattar, Raul J Rosenthal, and John M Morton

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Endoscopic Resection in the Esophagus., Andrew F Feczko and Brian E Louie

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Histochemistry in the diagnosis of non-neoplastic gastrointestinal disorders., Patrick L Fitzgibbons

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The Negative Impact of Body Mass Index on the Tumor Microenvironment in Colon Cancer: Results of a Prospective Trial., Devin C Flaherty, John R Jalas, Myung S Sim, Alexander Stojadinovic, Mladjan Protic, Delphine J Lee, and Anton J Bilchik

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Endovascular Coil Migration Into the Intestinal Lumen: Two Cases of Successful Nonoperative Management., Bryce French and D Hayes

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Diagnosis and Treatment of Invasive Aspergillus fumigatus Wound Infection Following Subtotal Colectomy for Perforated Toxic Megacolon in an Immunosuppressed Patient., Bryce French, Katherine Mandell, and Ryan Martinez