The Cancer Institute is a leader in cutting-edge treatments. Using a truly multidisciplinary approach, patients have access to advanced diagnostics, minimally invasive surgical interventions, and personalized genomic and immune-oncologic treatment options. Our team of cancer specialists – many of whom completed fellowships and specialty training at prestigious academic centers – offers comprehensive services for individuals with a cancer diagnosis.

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Submissions from 2024

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Type B Lactic Acidosis: A Very Rare but Fatal Complication of Gastrointestinal Solid Tumor., Fuad I Abaleka, Genanew Bedanie, Diego Olavarria Bernal, Selome F Yewedalsew, and Tasur Seen

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PRESTO: A Phase III, Open-Label Study of Intensification of Androgen Blockade in Patients With High-Risk Biochemically Relapsed Castration-Sensitive Prostate Cancer (AFT-19)., Rahul Aggarwal, Glenn Heller, David W Hillman, Han Xiao, Joel Picus, Mary-Ellen Taplin, Tanya Dorff, Leonard Appleman, Douglas Weckstein, Akash Patnaik, Alan Bryce, Daniel Shevrin, James Mohler, Daniel Anderson, Arpit Rao, Scott Tagawa, Alan Tan, Susan Halabi, Katharine Dooley, Patrick O'Brien, Ronald Chen, Charles J Ryan, Scott E Eggener, Michael J Morris, EORTC-55994 Study Group, and Brendan Curti (EORTC-55994 Study Group)

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Neoadjuvant Trebananib plus Paclitaxel-based Chemotherapy for Stage II/III Breast Cancer in the Adaptively Randomized I-SPY2 Trial-Efficacy and Biomarker Discovery., Kathy S Albain, Christina Yau, Emanuel F Petricoin, Denise M Wolf, Julie E Lang, A Jo Chien, Tufia Haddad, Andres Forero-Torres, Anne M Wallace, Henry G Kaplan, Lajos Pusztai, David Euhus, Rita Nanda, Anthony D Elias, Amy S Clark, Constantine Godellas, Judy C Boughey, Claudine Isaacs, Debu Tripathy, Janice Lu, Rachel L Yung, Rosa I Gallagher, Julia D Wulfkuhle, Lamorna Brown-Swigart, Gregor Krings, Yunn Yi Chen, David A Potter, Erica Stringer-Reasor, Sarah Blair, Smita M Asare, Amy Wilson, Gillian L Hirst, Ruby Singhrao, Meredith Buxton, Julia L Clennell, Ashish Sanil, Scott Berry, Adam L Asare, Jeffrey B Matthews, Angela M DeMichele, Nola M Hylton, Michelle Melisko, Jane Perlmutter, Hope S Rugo, W Fraser Symmans, Laura J Van't Veer, Douglas Yee, Donald A Berry, and Laura J Esserman

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A phase 1 study of triple-targeted therapy with BRAF, MEK, and AKT inhibitors for patients with BRAF-mutated cancers., Alain P Algazi, James Moon, Christopher D Lao, Bartosz Chmielowski, Kari L Kendra, Karl D Lewis, Rene Gonzalez, Kevin Kim, John E Godwin, Brendan D. Curti, Michaella Latkovic-Taber, Shirley H Lomeli, Brandon T Gufford, Philip O Scumpia, Roger S Lo, Megan Othus, and Antoni Ribas

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Large-scale genome-wide association study of 398,238 women unveils seven novel loci associated with high-grade serous epithelial ovarian cancer risk., Daniel R Barnes, Jonathan P Tyrer, Joe Dennis, Goska Leslie, Manjeet K Bolla, Michael Lush, Amber M Aeilts, Kristiina Aittomäki, Nadine Andrieu, Irene L Andrulis, Hoda Anton-Culver, Adalgeir Arason, Banu K Arun, Judith Balmaña, Elisa V Bandera, Rosa B Barkardottir, Lieke P V Berger, Amy Berrington de Gonzalez, Pascaline Berthet, Katarzyna Białkowska, Line Bjørge, Amie M Blanco, Marinus J Blok, Kristie A Bobolis, Natalia V Bogdanova, James D Brenton, Henriett Butz, Saundra S Buys, Maria A Caligo, Ian Campbell, Carmen Castillo, Kathleen B M Claes, Sarah V Colonna, Linda S Cook, Mary B Daly, Agnieszka Dansonka-Mieszkowska, Miguel de la Hoya, Anna deFazio, Allison DePersia, Yuan Chun Ding, Susan M Domchek, Thilo Dörk, Zakaria Einbeigi, Christoph Engel, D Gareth Evans, Lenka Foretova, Renée T Fortner, Florentia Fostira, Maria Cristina Foti, Eitan Friedman, Megan N Frone, Patricia A Ganz, Aleksandra Gentry-Maharaj, Gord Glendon, Andrew K Godwin, Anna González-Neira, Mark H Greene, Jacek Gronwald, Aliana Guerrieri-Gonzaga, Ute Hamann, Thomas V O Hansen, Holly R Harris, Jan Hauke, Florian Heitz, Frans B L Hogervorst, Maartje J Hooning, John L Hopper, Chad D Huff, David G Huntsman, Evgeny N Imyanitov, Louise Izatt, Anna Jakubowska, Paul A James, Ramunas Janavicius, Esther M John, Siddhartha Kar, Beth Y Karlan, Catherine J Kennedy, Lambertus A L M Kiemeney, Irene Konstantopoulou, Jolanta Kupryjanczyk, Yael Laitman, Ofer Lavie, Kate Lawrenson, Jenny Lester, Fabienne Lesueur, Carlos Lopez-Pleguezuelos, Phuong L Mai, Siranoush Manoukian, Taymaa May, Iain A McNeish, Usha Menon, Roger L Milne, Francesmary Modugno, Jennifer M Mongiovi, Marco Montagna, Kirsten B Moysich, Susan L Neuhausen, Finn C Nielsen, Catherine Noguès, Edit Oláh, Olufunmilayo I Olopade, Ana Osorio, Laura Papi, Harsh Pathak, Celeste L Pearce, Inge S Pedersen, Ana Peixoto, Tanja Pejovic, Pei-Chen Peng, Beth N Peshkin, Paolo Peterlongo, C Bethan Powell, Darya Prokofyeva, Miquel Angel Pujana, Paolo Radice, Muhammad U Rashid, Gad Rennert, George Richenberg, Dale P Sandler, Naoko Sasamoto, Veronica W Setiawan, Priyanka Sharma, Weiva Sieh, Christian F Singer, Katie Snape, Anna P Sokolenko, Penny Soucy, Melissa C Southey, Dominique Stoppa-Lyonnet, Rebecca Sutphen, Christian Sutter, Manuel R Teixeira, Kathryn L Terry, Liv Cecilie V Thomsen, Marc Tischkowitz, Amanda E Toland, Toon Van Gorp, Ana Vega, Digna R Velez Edwards, Penelope M Webb, Jeffrey N Weitzel, Nicolas Wentzensen, Alice S Whittemore, Stacey J Winham, Anna H Wu, Siddhartha Yadav, Yao Yu, Argyrios Ziogas, Andrew Berchuck, Fergus J Couch, Ellen L Goode, Marc T Goodman, Alvaro N Monteiro, Kenneth Offit, Susan J Ramus, Harvey A Risch, Joellen M Schildkraut, Mads Thomassen, Jacques Simard, Douglas F Easton, Michelle R Jones, Georgia Chenevix-Trench, Simon A Gayther, Antonis C Antoniou, and Paul D P Pharoah

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The Journey to Improve the College of American Pathologists Cancer Biomarker Reporting Protocols., Brett Baskovich, Alexander Baras, Raja R Seethala, Patrick L Fitzgibbons, Frank Schneider, Brent T Harris, and Joseph Khoury

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A Phase 1/2 Study to Evaluate the Safety and Activity of Nivolumab in Combination With Vorolanib, a Vascular Endothelial Growth Factor Tyrosine Kinase Inhibitor, in Patients With Refractory Thoracic Tumors., Kathryn E Beckermann, Christine M Bestvina, Badi El Osta, Rachel E Sanborn, Hossein Borghaei, Philip Edward Lammers, Giovanni Selvaggi, Jennifer G Whisenant, Ellen Heimann-Nichols, Lynne Berry, Chih-Yuan Hsu, Yu Shyr, Leora Horn, and Heather Wakelee

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Treatment practices and response in kaposiform hemangioendothelioma: A multicenter cohort study., Alexandra J Borst, Whitney Eng, Morgan Griffin, Kiersten W Ricci, Elissa Engel, Denise M Adams, Jillian Dayneka, Sally J Cohen-Cutler, Steven M Andreoli, Melinda D Wu, Allison P Wheeler, Kenneth M Heym, Shelley E Crary, Taizo A Nakano, Rachael R Schulte, Bhuvana A Setty, Thomas W McLean, Kristy S Pahl, Stefanos Intzes, Irina Pateva, Max Teitelbaum, Zili Zong, Yimei Li, and Michael R Jeng

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Sunitinib in Patients With Breast Cancer With, Carmen J Calfa, Michael Rothe, Pam K Mangat, Elizabeth Garrett-Mayer, Eugene R Ahn, Monika L Burness, Keerthi Gogineni, Nitin Rohatgi, Tareq Al Baghdadi, Alison Conlin, Anu Gaba, Omid Hamid, Jairam Krishnamurthy, Naga Jyothi Gavini, Philip J Gold, Jordi Rodon, Jens Rueter, Ramya Thota, Gina N Grantham, Dominique C Hinshaw, Abigail Gregory, Susan Halabi, and Richard L Schilsky

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Integrative systems biology reveals NKG2A-biased immune responses correlate with protection in infectious disease, autoimmune disease, and cancer., Daniel G Chen, Jingyi Xie, Jongchan Choi, Rachel H Ng, Rongyu Zhang, Sarah Li, Rick Edmark, Hong Zheng, Ben Solomon, Katie M Campbell, Egmidio Medina, Antoni Ribas, Purvesh Khatri, Lewis L Lanier, Philip J Mease, Jason D Goldman, Yapeng Su, and James R Heath

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MRI-derived radiomics assessing tumor-infiltrating macrophages enable prediction of immune-phenotype, immunotherapy response and survival in glioma., Di Chen, Rui Zhang, Xiaoming Huang, Chunxia Ji, Wei Xia, Ying Qi, Xinyu Yang, Lishuang Lin, Jing Wang, Haixia Cheng, Weijun Tang, Jinhua Yu, Dave S B Hoon, Jun Zhang, Xin Gao, and Yu Yao

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Preoperative immune checkpoint inhibition and cryoablation in early-stage breast cancer., Elizabeth Comen, Sadna Budhu, Yuval Elhanati, David B Page, Teresa Rasalan-Ho, Erika Ritter, Phillip Wong, George Plitas, Sujata Patil, Edi Brogi, Maxine Jochelson, Yolanda Bryce, Stephen B Solomon, Larry Norton, Taha Merghoub, and Heather L McArthur

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Consensus Recommendations on the Management of Toxicity Associated with CD3xCD20 Bispecific Antibody Therapy., Jennifer L Crombie, Tara Graff, Lorenzo Falchi, Yasmin H Karimi, Rajat Bannerji, Loretta J Nastoupil, Catherine Thieblemont, Renata Ursu, Nancy L Bartlett, Victoria R Nachar, Jonathan Weiss, Jane Osterson, Krish Patel, Joshua D Brody, Jeremy S Abramson, Matthew A Lunning, Nirav N Shah, Ayed Ayed, Manali Kamdar, Benjamin M Parsons, Paolo Caimi, Ian W Flynn, Alex F Herrera, Jeff P Sharman, Marshall McKenna, Philippe Armand, Brad S Kahl, Sonali M Smith, Andrew D Zelenetz, Lihua E Budde, Martin Hutchings, Tycel J Phillips, and Michael Dickinson

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Same day discharge colon surgery: is it financially worth it?, Karleigh R Curfman, Gabrielle E Blair, Callan L Kosnik, Sunshine A Pille, Michael E Parsons, Chirag A Shah, Christopher C Neighorn, and Laila Rashidi

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Paraneoplastic Syndrome Case Presented As Nystagmus and Ataxia., Khaled M Darwesh

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Paraneoplastic Syndrome Case Presented As Nystagmus and Ataxia., Khaled M Darwesh

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The future of targeting cytotoxic T-lymphocyte-associated protein-4: Is there a role?, Anna Maria Di Giacomo, Michael Lahn, Alexander Mm Eggermont, Bernard Fox, Ramy Ibrahim, Padmanee Sharma, James P Allison, and Michele Maio

Developing Combination Immunotherapy Trials with Vaccines that Contain Cancer’s Dark Matter, Bernard Fox

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A randomized phase III study of standard versus high-dose cytarabine with or without vorinostat for AML., Guillermo Garcia-Manero, Nikolai A Podoltsev, Megan Othus, John M Pagel, Jerald P Radich, Min Fang, David A Rizzieri, Guido Marcucci, Stephen A Strickland, Mark R Litzow, M Lynn Savoie, Bruno C Medeiros, Mikkael A Sekeres, Tara L Lin, Geoffrey L Uy, Bayard L Powell, Jonathan E Kolitz, Richard A Larson, Richard M Stone, David Claxton, James Essell, Selina M Luger, Sanjay R Mohan, Anna Moseley, Frederick R Appelbaum, and Harry P Erba

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Erosive pustular dermatosis-like eruption of the scalp secondary to amivantamab: A case series., Mariya N George, Riyad N H Seervai, and Susan Y Chon

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Randomized Placebo-Controlled, Biomarker-Stratified Phase Ib Microbiome Modulation in Melanoma: Impact of Antibiotic Preconditioning on Microbiome and Immunity., Isabella C Glitza, Yongwoo David Seo, Christine N Spencer, Jennifer R Wortman, Elizabeth M Burton, Farah A Alayli, Christopher P Loo, Shikha Gautam, Ashish Damania, Julie Densmore, Justin Fairchild, Christopher R Cabanski, Matthew C Wong, Christine B Peterson, Brian Weiner, Nathan Hicks, John G Auniņš, Christopher McChalicher, Emily Walsh, Michael T Tetzlaff, Omid Hamid, Patrick A Ott, Genevieve M Boland, Ryan J Sullivan, Kenneth F Grossmann, Nadim J Ajami, Theresa LaVallee, Matthew R Henn, Hussein A Tawbi, and Jennifer A Wargo

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Phase 1 trial of TPI 287, a microtubule stabilizing agent, in combination with bevacizumab in adults with recurrent glioblastoma., Samuel A Goldlust, Louis B Nabors, Sigmund Hsu, Nimish Mohile, Paul J Duic, Tara Benkers, Samuel Singer, Mayank Rao, Lori Cappello, Sandra L Silberman, and George Farmer

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Population Screening for High-Risk Patient Identification Partnership with CARE-Comprehensive Assessment, Risk, and Education., Ora K Gordon, Brad Bott, Nanor Parseghian, Kimberly K Childers, and Sandra Brown

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Multi-Cancer Early Detection Testing (MCED), Ora K Gordon, Brad Bott, Nanor Parseghian, Paul Psychogios, Kimberly K Childers, and Sandra Brown

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Characteristics and Survival Outcomes of Patients With Metastatic, Allan Hackshaw, Otto Fajardo, Urania Dafni, Hans Gelderblom, Pilar Garrido, Salvatore Siena, Matthew H Taylor, Walter Bordogna, and Christos Nikolaidis

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A phase 1/2 clinical trial of invariant natural killer T cell therapy in moderate-severe acute respiratory distress syndrome., Terese C Hammond, Marco A Purbhoo, Sapana Kadel, Jerome Ritz, Sarah Nikiforow, Heather Daley, Kit Shaw, Koen van Besien, Alexandra Gomez-Arteaga, Don Stevens, Waldo Ortuzar, Xavier Michelet, Rachel Smith, Darrian Moskowitz, Reed Masakayan, Burcu Yigit, Shannon Boi, Kah Teong Soh, John Chamberland, Xin Song, Yu Qin, Ilya Mishchenko, Maurice Kirby, Valeriia Nasonenko, Alexa Buffa, Jennifer S Buell, Dhan Chand, Marc van Dijk, Justin Stebbing, and Mark A Exley

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A data-driven approach to improve wellness and reduce recurrence in cancer survivors., Ramkumar Hariharan, Leroy Hood, and Nathan D Price

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Smoking Status and Survival in Patients With Early-Stage Primary Cutaneous Melanoma., Katherine M Jackson, Peter C Jones, Laura M Fluke, Trevan D Fischer, John F Thompson, Alistair J Cochran, Stacey L Stern, Mark B Faries, Dave S B Hoon, and Leland J Foshag

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Image-based multiplex immune profiling of cancer tissues: translational implications. A report of the International Immuno-oncology Biomarker Working Group on Breast Cancer., Chowdhury Arif Jahangir, David B Page, Glenn Broeckx, Claudia A Gonzalez, Caoimbhe Burke, Clodagh Murphy, Jorge S Reis-Filho, Amy Ly, Paul W Harms, Rajarsi R Gupta, Michael Vieth, Akira I Hida, Mohamed Kahila, Zuzana Kos, Paul J van Diest, Sara Verbandt, Jeppe Thagaard, Reena Khiroya, Khalid Abduljabbar, Gabriela Acosta Haab, Balazs Acs, Sylvia Adams, Jonas S Almeida, Isabel Alvarado-Cabrero, Farid Azmoudeh-Ardalan, Sunil Badve, Nurkhairul Bariyah Baharun, Enrique R Bellolio, Vydehi Bheemaraju, Kim Rm Blenman, Luciana Botinelly Mendonça Fujimoto, Octavio Burgues, Alexandros Chardas, Maggie Chon U Cheang, Francesco Ciompi, Lee Ad Cooper, An Coosemans, Germán Corredor, Flavio Luis Dantas Portela, Frederik Deman, Sandra Demaria, Sarah N Dudgeon, Mahmoud Elghazawy, Claudio Fernandez-Martín, Susan Fineberg, Stephen B Fox, Jennifer M Giltnane, Sacha Gnjatic, Paula I Gonzalez-Ericsson, Anita Grigoriadis, Niels Halama, Matthew G Hanna, Aparna Harbhajanka, Steven N Hart, Johan Hartman, Stephen Hewitt, Hugo M Horlings, Zaheed Husain, Sheeba Irshad, Emiel Am Janssen, Tatsuki R Kataoka, Kosuke Kawaguchi, Andrey I Khramtsov, Umay Kiraz, Pawan Kirtani, Liudmila L Kodach, Konstanty Korski, Guray Akturk, Ely Scott, Anikó Kovács, Anne-Vibeke Laenkholm, Corinna Lang-Schwarz, Denis Larsimont, Jochen K Lennerz, Marvin Lerousseau, Xiaoxian Li, Anant Madabhushi, Sai K Maley, Vidya Manur Narasimhamurthy, Douglas K Marks, Elizabeth S McDonald, Ravi Mehrotra, Stefan Michiels, Durga Kharidehal, Fayyaz Ul Amir Afsar Minhas, Shachi Mittal, David A Moore, Shamim Mushtaq, Hussain Nighat, Thomas Papathomas, Frederique Penault-Llorca, Rashindrie D Perera, Christopher J Pinard, Juan Carlos Pinto-Cardenas, Giancarlo Pruneri, Lajos Pusztai, Nasir Mahmood Rajpoot, Bernardo Leon Rapoport, Tilman T Rau, Joana M Ribeiro, David Rimm, Anne Vincent-Salomon, Joel Saltz, Shahin Sayed, Evangelos Hytopoulos, Sarah Mahon, Kalliopi P Siziopikou, Christos Sotiriou, Albrecht Stenzinger, Maher A Sughayer, Daniel Sur, Fraser Symmans, Sunao Tanaka, Timothy Taxter, Sabine Tejpar, Jonas Teuwen, E Aubrey Thompson, Trine Tramm, William T Tran, Jeroen van der Laak, Gregory E Verghese, Giuseppe Viale, Noorul Wahab, Thomas Walter, Yannick Waumans, Hannah Y Wen, Wentao Yang, Yinyin Yuan, John Bartlett, Sibylle Loibl, Carsten Denkert, Peter Savas, Sherene Loi, Elisabeth Specht Stovgaard, Roberto Salgado, William M Gallagher, and Arman Rahman

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Multi-omic profiling of simultaneous ductal carcinoma in situ and invasive breast cancer., Henry G Kaplan, Alexa K Dowdell, Anna B Berry, Racheli Ben Shimol, Fred L Robinson, Christopher A Carney, and Brian D. Piening

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The RAPID Consortium: A Platform for Clinical and Translational Pituitary Tumor Research., Michael Karsy, Varun Kshettry, Paul Gardner, Michael Chicoine, Juan C Fernandez-Miranda, James J Evans, Garni Barkhoudarian, Douglas Hardesty, Won Kim, Gabriel Zada, Tomiko Crocker, Ildiko Torok, and Andrew Little

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Pilot Study of High-Dose Pemetrexed in Patients with Progressive Chordoma., Santosh Kesari, Naveed Wagle, Jose Carrillo, Akanksha Sharma, Minhdan Nguyen, Judy D Truong, Jaya Mini Gill, Raffi Nersesian, Natsuko Nomura, Elnaz Rahbarlayegh, Garni Barkhoudarian, Walavan Sivakumar, Daniel F Kelly, Howard Krauss, Matias A Bustos, Dave Hoon, Lars Anker, Arun S Singh, Kamalesh K Sankhala, and Tiffany Juarez

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Zentangle® Pilot Study: A Mindfulness Exercise for Oncology Nurses., McKenzie Klee, Mary Heitschmidt, Theodore Hiemstra, Krista Lodewyk, Mary Ellen Hand, Madeline McIntosh, Catherine Yockey, and Jessica Bishop-Royse

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Radiation Therapy With or Without Cisplatin for Local Recurrences of Endometrial Cancer: Results From an NRG Oncology/GOG Prospective Randomized Multicenter Clinical Trial., Ann H Klopp, Danielle Enserro, Matthew Powell, Marcus Randall, Julian C Schink, Robert S Mannel, Laura Holman, David Bender, Christina L Kushnir, Floor Backes, Susan L Zweizig, Steven Waggoner, Kristin A Bradley, Lana DeSouza Lawrence, Parviz Hanjani, Christopher J Darus, William Small, Higinia R Cardenes, Jonathan M Feddock, and David S Miller

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Human-in-the-loop informed deep learning rectal tumor segmentation on pre-treatment MRI, Michael Kong, Marka R Crittenden, Michael J. Gough, Kristina H Young, and See full list of authors in comments

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Peristomal cutaneous amebiasis causing rapidly progressive necrotic wound of a left lower quadrant end colostomy., Debra Lai, Byung Kyu Kim, and Amir Bastawrous

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Markers of bone metabolism and overall survival in men with bone-metastatic hormone sensitive prostate cancer (HSPC): A subset analysis of SWOG S1216, a phase III trial of androgen deprivation with or without orteronel., Primo N Lara, Edward Mayerson, Erik Gertz, Catherine Tangen, Amir Goldkorn, Marta van Loan, Maha Hussain, Shilpa Gupta, Jingsong Zhang, Mamta Parikh, Przemyslaw W Twardowski, David I Quinn, Michael LeBlanc, Ian Thompson, and Neeraj Agarwal

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Digital twins in medicine., R Laubenbacher, B Mehrad, Ilya Shmulevich, and N Trayanova

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In Silico Approach to Molecular Profiling of the Transition from Ovarian Epithelial Cells to Low-Grade Serous Ovarian Tumors for Targeted Therapeutic Insights., Asim Leblebici, Ceren Sancar, Bahar Tercan, Zerrin Isik, Mehmet Emin Arayici, Ender Berat Ellidokuz, Yasemin Basbinar, and Nuri Yildirim

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Trastuzumab deruxtecan in patients with solid tumours harbouring specific activating HER2 mutations (DESTINY-PanTumor01): an international, phase 2 study., Bob T Li, Funda Meric-Bernstam, Aditya Bardia, Yoichi Naito, Salvatore Siena, Philippe Aftimos, Ian Churchill Anderson, Giuseppe Curigliano, Maria de Miguel, Maitri Kalra, Do-Youn Oh, Joon Oh Park, Sophie Postel-Vinay, Sun Young Rha, Taroh Satoh, Iben Spanggaard, Flavia Michelini, Ann Smith, Karime Kalil Machado, Cristina Saura, and DESTINY-PanTumor01 study group

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NK-92MI Cells Engineered with Anti-claudin-6 Chimeric Antigen Receptors in Immunotherapy for Ovarian Cancer., Junping Li, Hong Hu, Hui Lian, Shuo Yang, Manting Liu, Jinping He, Bihui Cao, Dongni Chen, Yuling Hu, Chen Zhi, Yan Shen, Xiaodie Ye, Bingjia He, Ming Zhao, Weijun Fan, Linfeng Xu, Rom Leidner, Qingde Wu, Lili Yang, and Zhenfeng Zhang

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Lung Cancer in Ever- and Never-Smokers: Findings from Multi-Population GWAS Studies., Yafang Li, Xiangjun Xiao, Jianrong Li, Younghun Han, Chao Cheng, Gail F Fernandes, Shannon E Slewitzke, Susan M Rosenberg, Meng Zhu, Jinyoung Byun, Yohan Bossé, James D McKay, Demetrios Albanes, Stephen Lam, Adonina Tardon, Chu Chen, Stig E Bojesen, Maria T Landi, Mattias Johansson, Angela Risch, Heike Bickeböller, H-Erich Wichmann, David C Christiani, Gad Rennert, Susanne M Arnold, Gary E Goodman, John K Field, Michael P A Davies, Sanjay Shete, Loïc Le Marchand, Geoffrey Liu, Rayjean J Hung, Angeline S Andrew, Lambertus A Kiemeney, Ryan Sun, Shanbeh Zienolddiny, Kjell Grankvist, Mikael Johansson, Neil E Caporaso, Angela Cox, Yun-Chul Hong, Philip Lazarus, Matthew B Schabath, Melinda C Aldrich, Ann G Schwartz, Ivan Gorlov, Kristen S Purrington, Ping Yang, Yanhong Liu, Joan E Bailey-Wilson, Susan M Pinney, Diptasri Mandal, James C Willey, Colette Gaba, Paul Brennan, Jun Xia, Hongbing Shen, and Christopher I Amos

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SITC Clinical Immuno-Oncology Network (SCION) commentary on measurement and interpretation of essential biomarkers in early clinical trials., Michael T Lotze, Tricia Cottrell, Carlo Bifulco, Laura Chow, Leslie Cope, Sacha Gnjatic, Holden T Maecker, and Joe Yeong Poh Shen

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Implementing a Graduate Nurse Residency Program, Julianne Luttrell and Leah Scaramuzzo

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Evaluation of potential biomarkers for lenvatinib plus pembrolizumab among patients with advanced endometrial cancer: results from Study 111/KEYNOTE-146., Vicky Makker, Matthew H Taylor, Carol Aghajanian, Allen L Cohn, Marcia S Brose, Christopher Di Simone, Zhu Alexander Cao, Leah Suttner, Andrey Loboda, Razvan Cristescu, Petar Jelinic, Robert Orlowski, Lea Dutta, Junji Matsui, Corina E Dutcus, Yukinori Minoshima, and Mark J Messing

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Hypoxia drives shared and distinct transcriptomic changes in two invasive glioma stem cell lines., Valerie J Marallano, Mary E Ughetta, Rut Tejero, Sidhanta Nanda, Rohana Ramalingam, Lauren Stalbow, Anirudh Sattiraju, Yong Huang, Aarthi Ramakrishnan, Li Shen, Alexandre Wojcinski, Santosh Kesari, Hongyan Zou, Alexander M Tsankov, and Roland H Friedel

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The Dance Between Tumor Molecular Biology and Antitumor Immune Response., K A Margolin

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Evaluation of the EMulate Therapeutics Voyager's ultra-low radiofrequency energy in murine model of glioblastoma., Rajesh Mukthavaram, Pengfei Jiang, Sandra Pastorino, Natsuko Nomura, Feng Lin, and Santosh Kesari

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Tissue-specific thresholds of mutation burden associated with anti-PD-1/L1 therapy benefit and prognosis in microsatellite-stable cancers., Maishara Muquith, Magdalena Espinoza, Andrew Elliott, Joanne Xiu, Andreas Seeber, Wafik El-Deiry, Emmanuel S Antonarakis, Stephanie L Graff, Michael J Hall, Hossein Borghaei, Dave S B Hoon, Stephen V Liu, Patrick C Ma, Rana R McKay, Trisha Wise-Draper, John Marshall, George W Sledge, David Spetzler, Hao Zhu, and David Hsiehchen

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Imaging as an early biomarker to predict sensitivity to everolimus for progressive NF2-related vestibular schwannoma., Phioanh Leia Nghiemphu, Jeremie Vitte, Eva Dombi, Thien Nguyen, Naveed Wagle, Akira Ishiyama, Ali R Sepahdari, David Cachia, Brigitte C Widemann, Derald E Brackmann, Joni K Doherty, Michel Kalamarides, and Marco Giovannini

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Adjuvant Radiotherapy for Surgically Resected Stage III Merkel Cell Carcinoma., Seyed Saeed Pairawan, Chloe E Dominguez, Naveenraj Solomon, David Caba-Molina, Michael O'Leary, Mark E Reeves, and Jukes P Namm

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Gene regulatory network topology governs resistance and treatment escape in glioma stem-like cells., James H Park, Parvinder Hothi, Adrian Lopez Garcia de Lomana, Min Pan, Rachel Calder, Serdar Turkarslan, Wei-Ju Wu, Hwahyung Lee, Anoop P Patel, Charles Cobbs, Sui Huang, and Nitin S Baliga

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Posterior Ischemic Optic Neuropathy Because of Hematologic Malignancy., Ankush U Patel, Uresh S Patel, and Eugene May

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7P Patient-relevant endpoints from PAPILLON: Amivantamab plus chemotherapy vs chemotherapy as first-line treatment of EGFR exon 20 insertion-mutated (Ex20ins) advanced NSCLC, L Paz-Ares, Rachel E Sanborn, and See full list of authors in comments

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Association between class III obesity and overall survival in previously untreated younger patients with acute myeloid leukemia enrolled on SWOG S1203, Mary-Elizabeth Percival, Michelle Zhang, Megan Othus, Kerry McMillen, Harry Erba, Guillermo Garcia-Manero, John Pagel, and Mohamed Sorror

Standardizing Chemotherapy Education Patient Practices to Increase Nurses’ Self-Efficacy, Julia Persons

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BRAF(V600E)-mutant metastatic NSCLC: disease overview and treatment landscape, David Planchard, Rachel E Sanborn, Marcelo V Negrao, Aria Vaishnavi, and Egbert F Smit

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Circulating cancer-specific CD8 T cell frequency is associated with response to PD-1 blockade in Merkel cell carcinoma., Thomas Pulliam, Saumya Jani, Lichen Jing, Heeju Ryu, Ana Jojic, Carolyn Shasha, Jiajia Zhang, Rima Kulikauskas, Candice Church, Charlie Garnett-Benson, Ted Gooley, Aude Chapuis, Kelly G Paulson, Kellie N Smith, Drew M Pardoll, Evan W Newell, David M Koelle, Suzanne L Topalian, and Paul Nghiem

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Mutation Patterns Predict Drug Sensitivity in Acute Myeloid Leukemia., Guangrong Qin, Jin Dai, Sylvia Chien, Timothy J Martins, Brenda Loera, Quy H Nguyen, Melanie L Oakes, Bahar Tercan, Boris Aguilar, Lauren Hagen, Jeannine McCune, Richard Gelinas, Raymond J Monnat, Ilya Shmulevich, and Pamela S Becker

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Exercise-Related Physical Activity Relates to Brain Volumes in 10,125 Individuals., Cyrus A Raji, Somayeh Meysami, Sam Hashemi, Saurabh Garg, Nasrin Akbari, Gouda Ahmed, Yosef Gavriel Chodakiewitz, Thanh Duc Nguyen, Kellyann Niotis, David A Merrill, and Rajpaul Attariwala

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Genome-wide association analyses of ovarian cancer patients undergoing primary debulking surgery identify candidate genes for residual disease., Dhanya Ramachandran, Jonathan P Tyrer, Stefan Kommoss, Anna DeFazio, Marjorie J Riggan, AOCS Group, Penelope M Webb, Peter A Fasching, Diether Lambrechts, María J García, Cristina Rodríguez-Antona, Marc T Goodman, Francesmary Modugno, Kirsten B Moysich, Beth Y Karlan, Jenny Lester, Susanne K Kjaer, Allan Jensen, Estrid Høgdall, Ellen L Goode, William A Cliby, Amanika Kumar, Chen Wang, Julie M Cunningham, Stacey J Winham, Alvaro N Monteiro, Joellen M Schildkraut, Daniel W Cramer, Kathryn L Terry, Linda Titus, Line Bjorge, Liv Cecilie Vestrheim Thomsen, OPAL Study Group, Tanja Pejovic, Claus K Høgdall, Iain A McNeish, Taymaa May, David G Huntsman, Jacobus Pfisterer, Ulrich Canzler, Tjoung-Won Park-Simon, Willibald Schröder, Antje Belau, Lars Hanker, Philipp Harter, Jalid Sehouli, Rainer Kimmig, Nikolaus de Gregorio, Barbara Schmalfeldt, Klaus Baumann, Felix Hilpert, Alexander Burges, Boris Winterhoff, Peter Schürmann, Lisa-Marie Speith, Peter Hillemanns, Andrew Berchuck, Sharon E Johnatty, Susan J Ramus, Georgia Chenevix-Trench, Paul D P Pharoah, Thilo Dörk, and Florian Heitz

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Norepinephrine induces anoikis resistance in high-grade serous ovarian cancer precursor cells., Hunter D Reavis, Stefan M Gysler, Grace B McKenney, Matthew Knarr, Hannah J Lusk, Priyanka Rawat, Hannah S Rendulich, Marilyn A Mitchell, Dara S Berger, Jamie Moon, Suyeon Ryu, Monica Mainigi, Marcin P Iwanicki, Dave Hoon, Laura M Sanchez, and Ronny Drapkin

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Order From Chaos: The Benefits of Standardized Nomenclature in Radiation Oncology., Susan L Richardson, Walter R Bosch, Charles S Mayo, Todd R McNutt, Jean M Moran, Richard A Popple, Ying Xiao, and Elizabeth L Covington

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Regorafenib in Patients With Solid Tumors With, Vaibhav Sahai, Michael Rothe, Pam K Mangat, Elizabeth Garrett-Mayer, Vijay Suhag, Elie G Dib, Inderjit Mehmi, Kunal C Kadakia, Evan Pisick, Herbert L Duvivier, Phat Le, Rui Li, David P Michelin, Ryan E Wilcox, Gina N Grantham, Dominique C Hinshaw, Abigail Gregory, Susan Halabi, and Richard L Schilsky

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Exploring the Genomic Landscape of Hepatobiliary Cancers to Establish a Novel Molecular Classification System., Anthony J Scholer, Rebecca Marcus, Mary Garland-Kledzik, Debopriya Ghosh, Miquel Ensenyat-Mendez, Joshua Germany, Juan A Santamaria-Barria, Adam Khader, Javier I Orozco, and Melanie Goldfarb

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Socially vulnerable patients are more likely to fail outpatient management of symptomatic cholelithiasis., Udai S Sibia, John R Klune, Cristina B Feather, Deanna Rider, Douglas Hanes, and Richard Essner

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Early Experiences With Bundled Payments for Care Improvement for Major Bowel Surgery., Udai S Sibia, John R Klune, Said Saiolghalam, and Anton J Bilchik

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Analysis of 10-year trends in Medicare Physician Fee Schedule payments in surgery., Udai S Sibia, Janelle-Cheri Millen, John R Klune, Anton Bilchik, and Leland J Foshag

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Impact of Fall Education to Oncology Staff on Oncology Patient Fall Rates, Danni Sloane

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Safety and efficacy of zandelisib plus zanubrutinib in previously treated follicular and mantle cell lymphomas., Jacob D Soumerai, Catherine S Diefenbach, Deepa Jagadeesh, Adam Asch, Abhijeet Kumar, Michaela L Tsai, Thomas A Jandl, Izidore S Lossos, Vaishalee P Kenkre, Farrukh Awan, William Novotny, Jane Huang, Lu Miao, Prabhu Rajagopalan, Richard G Ghalie, and Andrew D Zelenetz

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Advances and challenges in cancer immunoprevention and immune interception., Sasha Stanton, Philip E Castle, Olivera J Finn, Shizuko Sei, and Leisha A Emens

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A real-world study of treatment sequences and second-line clinical outcomes in patients with HER2-positive metastatic breast cancer in US community practice., Della Varghese, Giovanna I Cruz, Colden Johanson, Liz Toland, Miguel Miranda, Eleanor C Faherty, David Harland, and Henry G Kaplan

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Management of Neurologic Complications in Patients with Brain and Spine Tumors., Alipi V Bonm and Lynne P Taylor

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Interventions to Mitigate Financial Toxicity in Adult Patients with Cancer in the United States: A Scoping Review., Seiichi Villalona, Brenda S Castillo, Carlos Chavez Perez, Alana Ferreira, Isoris Nivar, Juan Cisneros, and Carmen E Guerra

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Incidence and Presenting Characteristics of Angiosarcoma in the US, 2001-2020., Michael J Wagner, Vinod Ravi, Stephanie K Schaub, Ed Y Kim, Jeremy Sharib, Harveshp Mogal, Min Park, Michaela Tsai, Daniela Duarte-Bateman, Anthony Tufaro, Elizabeth T Loggers, Lee D Cranmer, Bonny Chau, Michael J Hassett, Juneko Grilley-Olson, and Kelly G Paulson

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Individualised neoantigen therapy mRNA-4157 (V940) plus pembrolizumab versus pembrolizumab monotherapy in resected melanoma (KEYNOTE-942): a randomised, phase 2b study., Jeffrey S Weber, Matteo S Carlino, Adnan Khattak, Tarek Meniawy, George Ansstas, Matthew H Taylor, Kevin B Kim, Meredith McKean, Georgina V Long, Ryan J Sullivan, Mark Faries, Thuy T Tran, C Lance Cowey, Andrew Pecora, Montaser Shaheen, Jennifer Segar, Theresa Medina, Victoria Atkinson, Geoffrey T Gibney, Jason J Luke, Sajeve Thomas, Elizabeth I Buchbinder, Jane A Healy, Mo Huang, Manju Morrissey, Igor Feldman, Vasudha Sehgal, Celine Robert-Tissot, Peijie Hou, Lili Zhu, Michelle Brown, Praveen Aanur, Robert S Meehan, and Tal Zaks

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Natural Killer Cell Infiltration in Prostate Cancers Predict Improved Patient Outcomes., Nicholas A Zorko, Allison Makovec, Andrew Elliott, Samuel Kellen, John R Lozada, Ali T Arafa, Martin Felices, Madison Shackelford, Pedro Barata, Yousef Zakharia, Vivek Narayan, Mark N Stein, Kevin K Zarrabi, Akash Patniak, Mehmet A Bilen, Milan Radovich, George Sledge, Wafik S El-Deiry, Elisabeth I Heath, Dave Hoon, Chadi Nabhan, Jeffrey S Miller, Justin H Hwang, and Emmanuel S Antonarakis

Submissions from 2023

Deep Learning Applications Using H&E Images Improve Clinical Sequencing Workflows, J Abel, Brian Piening, Carlo Bifulco, and See full list of authors in comments

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Heterogeneity in the Metastatic Microenvironment: JunB-Expressing Microglia Cells as Potential Drivers of Melanoma Brain Metastasis Progression., Orit Adir, Orit Sagi-Assif, Tsipi Meshel, Shlomit Ben-Menachem, Metsada Pasmanik-Chor, Dave Hoon, Isaac P Witz, and Sivan Izraely

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Multi-omics inference of differential breast cancer-related transcriptional regulatory network gene hubs between young Black and White patients., Boris Aguilar, Kawther Abdilleh, and George K Acquaah-Mensah

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Pertuzumab Plus Trastuzumab in Patients With Endometrial Cancer With, Eugene R Ahn, Michael Rothe, Pam K Mangat, Elizabeth Garrett-Mayer, Hussein M Ali-Ahmad, John Chan, Michael L Maitland, Sapna R Patel, Zachary Reese, Ani S Balmanoukian, Charles W Drescher, Rui Li, Apostolia M Tsimberidou, Charles A Leath, Raegan O'Lone, Gina N Grantham, Susan Halabi, and Richard L Schilsky

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AAPM BTSC Report 377: Physicist Brachytherapy Training in 2021-A survey of therapeutic medical physics residency program directors., Manik Aima, Samantha J Simiele, Susan L Richardson, and Christopher S Melhus

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Case report: ex vivo tumor organoid drug testing identifies therapeutic options for stage IV ovarian carcinoma, Marwah Al-Aloosi, Amanda M Prechtl, Payel Chatterjee, Brady Bernard, Christopher J Kemp, Rachele Rosati, Robert L Diaz, Lauren R Appleyard, Shalini Pereira, Alex Rajewski, Amber McDonald, Eva J Gordon, and Carla Grandori

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Liquid biopsies and minimal residual disease in myeloid malignancies., Sabine Allam, Kristina Nasr, Farhan Khalid, Zunairah Shah, Mahammed Ziauddin Khan Suheb, Sana Mulla, Sindhu Vikash, Maroun Bou Zerdan, Faiz Anwer, and Chakra P Chaulagain

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Vemurafenib- and Cobimetinib-Associated Drug Reaction With Eosinophilia and Systemic Symptoms in a Patient With Metastatic Melanoma., Miriam Al-Saedy, Salsabeal Al-Saedy, and Chad Rieck

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Gut microbiota analyses of inflammatory bowel diseases from a representative Saudi population., Raed M Alsulaiman, Abdulaziz A Al-Quorain, Fahad A Al-Muhanna, Stanley Piotrowski, Ezzeddin A Kurdi, Chittibabu Vatte, Ahmed A Alquorain, Noorah H Alfaraj, Abdulaziz M Alrezuk, Fred L Robinson, Alexa K Dowdell, Turki A Alamri, Lauren Hamilton, Hetal Lad, Hui Gao, Divya Gandla, Brendan J Keating, Ryan Meng, Brian D. Piening, and Amein K Al-Ali

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Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 1st-3rd, 2022-Naples, Italy)., Paolo A Ascierto, Sanjiv S Agarwala, Allison Betof Warner, Marc S Ernstoff, Bernard A Fox, Thomas F Gajewski, Jérôme Galon, Claus Garbe, Brian R Gastman, Jeffrey E Gershenwald, Pawel Kalinski, Michelle Krogsgaard, Rom S Leidner, Roger S Lo, Alexander M Menzies, Olivier Michielin, Poulikos I Poulikakos, Jeffrey S Weber, Corrado Caracò, Iman Osman, Igor Puzanov, and Magdalena Thurin

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The "Great Debate" at Immunotherapy Bridge 2022, Naples, November 30th-December 1st, 2022., Paolo A Ascierto, Renier Brentjens, Samir N Khleif, Kunle Odunsi, Katayoun Rezvani, Marco Ruella, Ryan J Sullivan, Bernard A Fox, and Igor Puzanov

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Nivolumab and Relatlimab in Patients With Advanced Melanoma That Had Progressed on Anti-Programmed Death-1/Programmed Death Ligand 1 Therapy: Results From the Phase I/IIa RELATIVITY-020 Trial., Paolo Antonio Ascierto, Evan J Lipson, Reinhard Dummer, James Larkin, Georgina V Long, Rachel E Sanborn, Vanna Chiarion-Sileni, Brigitte Dréno, Stéphane Dalle, Dirk Schadendorf, Margaret K Callahan, Marta Nyakas, Victoria Atkinson, Carlos Alberto Gomez-Roca, Naoya Yamazaki, Hussein A Tawbi, Naomey Sarkis, Deepti Warad, Sonia Dolfi, Priyam Mitra, Satyendra Suryawanshi, and Jean-Jacques Grob

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Rare presence of Charcot-Leyden crystals in acute myeloid leukemia., Sujan Badal, Mahnoosh Taheri, Peter Jiang, and Kirstine Oh

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An expanded safety/feasibility study of the EMulate Therapeutics Voyager™ System in patients with recurrent glioblastoma., Garni Barkhoudarian, Michael Badruddoja, Nicholas Blondin, Sajeel Chowdhary, Charles Cobbs, Julius Paul Duic, John Paul Flores, Ekokobe Fonkem, Edward McClay, Louis Burt Nabors, Michael Salacz, Lynn Taylor, Brian Vaillant, Jaya Gill, and Santosh Kesari

A phase 1 study of AGEN2373, a novel CD137 agonist antibody designed to avoid hepatoxicity, in patients with advanced solid tumors, MA Barve, MH Taylor, and See all authors in comments

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Early Utilization of Mechanical Circulatory Support in Acute Myocardial Infarction Complicated by Cardiogenic Shock: The National Cardiogenic Shock Initiative., Mir B Basir, Alejandro Lemor, Sarah Gorgis, Kirit C Patel, Brian C Kolski, Aditya S Bharadwaj, Joshua W Todd, Behnam N Tehrani, Alexander G Truesdell, David M Lasorda, Thomas A Lalonde, Amir Kaki, Theodore L Schrieber, Nainesh C Patel, Shaun R Senter, Joseph L Gelormini, Steven P Marso, Ayaz M Rahman, Robert E Federici, Charles E Wilkins, A Thomas McRae, Ali Nsair, Christopher P Caputo, Matheen A Khuddus, Juan J Chahin, Allison G Dupont, Andrew M Goldsweig, Michael J Lim, Navin K Kapur, David H W Wohns, Yueren Zhou, Michael J Hacala, and William W O'Neill

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Health-care expenditures are less for minimally invasive than open colectomy for colon cancer: A US commercial claims database analysis., Amir L Bastawrous, I-Fan Shih, Yanli Li, Marissa Khalil, Biruk Almaz, and Robert K Cleary

Cancer Immunotherapy 102, RB Bell

Enhancing Anti-tumor Immunity for the Treatment of Head and Neck Cancer, RB Bell

Enhancing Anti-tumor Immunity for the Treatment of Head and Neck Cancer, RB Bell

Neoadjuvant Immunoradiotherapy Prior to Surgery: Towards a New Paradigm in the Management of Locally Advanced Head and Neck Cancer, RB Bell

State of the Art of Head and Neck Cancer Immunotherapy Translational Research, RB Bell

Transforming Treatment Approaches in Head and Neck Cancer: The Potential of Immunotherapy in Neoadjuvant, Adjuvant and Metastatic Disease, RB Bell