The Cancer Institute is a leader in cutting-edge treatments. Using a truly multidisciplinary approach, patients have access to advanced diagnostics, minimally invasive surgical interventions, and personalized genomic and immune-oncologic treatment options. Our team of cancer specialists – many of whom completed fellowships and specialty training at prestigious academic centers – offers comprehensive services for individuals with a cancer diagnosis.

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Submissions from 2023

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Race, Gene Expression Signatures, and Clinical Outcomes of Patients With High-Risk Early Breast Cancer., Beverly Kyalwazi, Christina Yau, Michael J Campbell, Toshio F Yoshimatsu, A Jo Chien, Anne M Wallace, Andres Forero-Torres, Lajos Pusztai, Erin D Ellis, Kathy S Albain, Anne H Blaes, Barbara B Haley, Judy C Boughey, Anthony D Elias, Amy S Clark, Claudine J Isaacs, Rita Nanda, Hyo S Han, Rachel L Yung, Debasish Tripathy, Kristen K Edmiston, Rebecca K Viscusi, Donald W Northfelt, Qamar J Khan, Smita M Asare, Amy Wilson, Gillian L Hirst, Ruixiao Lu, William Fraser Symmans, Douglas Yee, Angela M DeMichele, Laura J van 't Veer, Laura J Esserman, and Olufunmilayo I Olopade

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Efficacy and Safety of Mitomycin Gel (UGN-101) as an Adjuvant Therapy After Complete Endoscopic Management of Upper Tract Urothelial Carcinoma., Craig Labbate, Solomon Woldu, Katie Murray, Kyle Rose, Wade Sexton, Isamu Tachibana, Hristov Kaimakliotis, Joseph Jacob, Rian Dickstein, Jennifer Linehan, Alan Nieder, Marc Bjurlin, Mitchell Humphreys, Saum Ghodoussipor, Marcus Quek, Michael O'Donnell, Brian Eisner, Adam Feldman, Yair Lotan, and Surena F Matin

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Uterine Inflammatory Myofibroblastic Tumors: Proposed Risk Stratification Model Using Integrated Clinicopathologic and Molecular Analysis., Nicholas R Ladwig, Gregory R Bean, Melike Pekmezci, John Boscardin, Nancy M Joseph, Nicole Therrien, Ankur R Sangoi, Brian D. Piening, Venkatesh Rajamanickam, Matthew Galvin, Brady Bernard, Charles Zaloudek, Joseph T Rabban, Karuna Garg, and Sarah E Umetsu

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Bone Biomarkers and Subsequent Survival in Men with Hormone-sensitive Prostate Cancer: Results from the SWOG S1216 Phase 3 Trial of Androgen Deprivation Therapy with or Without Orteronel., Primo N Lara, Edward Mayerson, Erik Gertz, Catherine Tangen, Amir Goldkorn, Marta van Loan, Maha Hussain, Shilpa Gupta, Jingsong Zhang, Mamta Parikh, Przemyslaw Twardowski, David I Quinn, Michael LeBlanc, Nicholas J Vogelzang, Ian Thompson, and Neeraj Agarwal

Updates in Cardio-Oncology, ME Layoun

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Regulation of human and mouse bystander T cell activation responses by PD-1., Catherine T Le, Logan V Vick, Craig Collins, Cordelia Dunai, Michael K Sheng, Lam T Khuat, Isabel Barao, Sean J Judge, Ethan G Aguilar, Brendan Curti, Maneesh Dave, Dan L Longo, Bruce R Blazar, Robert J Canter, Arta M Monjazeb, and William J Murphy

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Interprofessional Collaboration Optimizes Oncology Navigation Efficiency and Value​, Lauri Ledbeter, Whitney Daws, Rebekah Hart, and Lindsay Shimizu

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Safety of adjuvant atezolizumab after pneumonectomy/bilobectomy in stage II-IIIA non-small cell lung cancer in the randomized phase III IMpower010 trial., Jay M Lee, Eric Vallieres, Beiying Ding, Ann Johnson, Jan Bhagwakar, Sanam Rashidi, Qian Cindy Zhu, Barbara J Gitlitz, Benny Weksler, Kimberly E Costas, and Nasser Altorki

Transforming Treatment Approaches in Head and Neck Cancer: The Potential of Immunotherapy in Neoadjuvant, Adjuvant and Metastatic Disease, R Leidner

TCR engagers VS CAR-T, Rom Leidner

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First-in-human phase I/Ib study of NIZ985, a recombinant heterodimer of IL-15 and IL-15Rα, as a single agent and in combination with spartalizumab in patients with advanced and metastatic solid tumors., Rom Leidner, Kevin Conlon, Douglas G McNeel, Andrea Wang-Gillam, Sumati Gupta, Robert Wesolowski, Monica Chaudhari, Nadia Hassounah, Jong Bong Lee, Lang Ho Lee, Jessica A O'Keeffe, Nancy Lewis, George N Pavlakis, and John A Thompson

Amivantamab in Patients with Advanced NSCLC and MET Exon 14 Skipping Mutation: Results from the CHRYSALIS Study, N Leighl, Rachel Sanborn, and See all authors in comments

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Radiofrequency Ablation Provides Rapid and Durable Pain Relief for the Palliative Treatment of Lytic Bone Metastases Independent of Radiation Therapy: Final Results from the OsteoCool Tumor Ablation Post-Market Study., Jason Levy, Elizabeth David, Thomas Hopkins, Jonathan Morris, Nam D Tran, Hamed Farid, Francesco Massari, William G O'Connell, Alexander Vogel, Afshin Gangi, Peter Sunenshine, Robert Dixon, Nicolas Von der Höh, and Sandeep Bagla

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Preparing Hematology/Oncology Fellows for Success: Implementing an Annual Career Development and Research Retreat., Akeem R Lewis, Grace M Choong, Elizabeth Cathcart-Rake, Narjust Florez, Urshila Durani, Siddhartha Yadav, Harry Fuentes, Karl Sorensen, Daniel S Childs, Antoine Saliba, Jonas Paludo, and Timothy J Hobday

Phase 1/1b study of PRGN-3005 autologous UltraCAR-T cells manufactured overnight for infusion next day to advanced stage platinum resistant ovarian cancer patients, JB Liao, SE Stanton, and See all authors in comments

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Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial., Linda M Liau, Keyoumars Ashkan, Steven Brem, Jian L Campian, John E Trusheim, Fabio M Iwamoto, David D Tran, George Ansstas, Charles Cobbs, Jason A Heth, Michael E Salacz, Stacy D'Andre, Robert D Aiken, Yaron A Moshel, Joo Y Nam, Clement P Pillainayagam, Stephanie A Wagner, Kevin A Walter, Rekha Chaudhary, Samuel A Goldlust, Ian Y Lee, Daniela A Bota, Heinrich Elinzano, Jai Grewal, Kevin Lillehei, Tom Mikkelsen, Tobias Walbert, Steven Abram, Andrew J Brenner, Matthew G Ewend, Simon Khagi, Darren S Lovick, Jana Portnow, Lyndon Kim, William G Loudon, Nina L Martinez, Reid C Thompson, David E Avigan, Karen L Fink, Francois J Geoffroy, Pierre Giglio, Oleg Gligich, Dietmar Krex, Scott M Lindhorst, Jose Lutzky, Hans-Jörg Meisel, Minou Nadji-Ohl, Lhagva Sanchin, Andrew Sloan, Lynne P Taylor, Julian K Wu, Erin M Dunbar, Arnold B Etame, Santosh Kesari, David Mathieu, David E Piccioni, David S Baskin, Michel Lacroix, Sven-Axel May, Pamela Z New, Timothy J Pluard, Steven A Toms, Victor Tse, Scott Peak, John L Villano, James D Battiste, Paul J Mulholland, Michael L Pearlman, Kevin Petrecca, Michael Schulder, Robert M Prins, Alton L Boynton, and Marnix L Bosch

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Route of Administration for UGN-101 and Impact on Oncological and Safety Outcomes., Jennifer M Linehan, Josh Gottlieb, Solomon L Woldu, Craig Labbate, Kyle Rose, Wade Sexton, Hristos Kaimakliotis, Joseph Jacob, Rian Dickstein, Alan Nieder, Marc Bjurlin, Mitchell Humphreys, Saum Ghodoussipor, Marcus Quek, Michael O'Donnell, Brian H Eisner, Adam S Feldman, Surena F Matin, Yair Lotan, and Katie S Murray

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Corrigendum to "Route of Administration for UGN-101 and Impact on Oncological and Safety Outcomes" [Eur. Urol. Focus (2023)]., Jennifer M Linehan, Josh Gottlieb, Solomon L Woldu, Craig Labbate, Kyle Rose, Wade Sexton, Hristos Kaimakliotis, Joseph Jacob, Rian Dickstein, Alan Nieder, Marc Bjurlin, Mitchell Humphreys, Saum Ghodoussipour, Marcus Quek, Michael O'Donnell, Brian H Eisner, Adam S Feldman, Surena F Matin, Yair Lotan, and Katie S Murray

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Long-term survival after salvage pemetrexed for refractory primary T-cell lymphoma of the CNS., Andy Liu, Huda Alalami, Xuemo Fan, Chirag Patil, Jaya M Gill, Santosh Kesari, and Jethro Hu

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Chromatin insulation orchestrates matrix metalloproteinase gene cluster expression reprogramming in aggressive breast cancer tumors., Pere Llinàs-Arias, Miquel Ensenyat-Mendez, Sandra Íñiguez-Muñoz, Javier I Orozco, Betsy Valdez, Matthew P Salomon, Chikako Matsuba, Maria Solivellas-Pieras, Andrés F Bedoya-López, Borja Sesé, Anja Mezger, Mattias Ormestad, Fernando Unzueta, Siri H Strand, Alexander D Boiko, E Shelley Hwang, Javier Cortés, Maggie L DiNome, Manel Esteller, Mathieu Lupien, and Diego M Marzese

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3-D chromatin conformation, accessibility, and gene expression profiling of triple-negative breast cancer., Pere Llinàs-Arias, Miquel Ensenyat-Méndez, Javier I Orozco, Sandra Íñiguez-Muñoz, Betsy Valdez, Chuan Wang, Anja Mezger, Eunkyoung Choi, Yan Zhou Tran, Liqun Yao, Franziska Bonath, Remi-André Olsen, Mattias Ormestad, Manel Esteller, Mathieu Lupien, and Diego M Marzese

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Trends and Factors Associated with Prophylactic Anticoagulation Strategies in COVID-19: an Analysis of the AHA COVID-19 CVD Registry, Mathew Lopes, Hsin-Fang Li, Reed Sorensen, Sandeep Das, Steven M. Bradley, James A. de Lemos, Gregory Andrew Roth, Tracy Wang, Erin Ann Bohula, and Tyler J Gluckman

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An Analysis of Patient Characteristics Associated with Myelosuppression Among Small Cell Lung Cancer (SCLC) Patients Treated in US Community Cancer Care Practices, L Lopez-Gonzalez, Rachel E Sanborn, Roshanthi Weerasinghe, Amy S. Parrish, and See full list of authors in comments

SGN-B6A, an integrin beta-6 (ITGB6)-targeted antibody-drug conjugate (ADC), in patients with advanced solid tumors: Updated results from a phase 1 study (SGNB6A-001), JS Lopez, Rachel Sanborn, and See all authors in comments

Long-term efficacy, safety, and predictors of response to amivantamab among patients with post-platinum EGFR Ex20ins-mutated advanced NSCLC, PG Lopez, Rachel E Sanborn, and See full list of authors in comments

Long-term efficacy, safety, and predictors of response to amivantamab among patients with post-platinum EGFR Ex20ins-mutated advanced NSCLC, PG Lopez, RE Sanborn, and See full list of authors in comments

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Feasibility of circulating tumor DNA (ctDNA) to guide organ preservation in patients with node-negative rectal cancer undergoing neoadjuvant chemotherapy, excision, and observation in the phase II CCTG CO.28 trial, Jonathan M. Loree, Hagen F Kennecke, and See full list of authors in comments

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ACR-ARS Practice Parameter for Radiation Oncology., Simon Lo, Samuel Chao, Eleanor Harris, Jonathan Knisely, Join Y Luh, Pranshu Mohindra, Tony S Quang, Jason Ye, William Small, and Naomi R Schechter

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Commentary: The next step forward for enhanced recovery after surgery: Postdischarge benefits., Brian Louie

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Lorigerlimab, a bispecific PD-1×CTLA-4 DART molecule in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC): A phase 1 expansion (exp) cohort., Jason J. Luke, Rachel E Sanborn, and See full list of authors in comments

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CT251 / 14 - Phase 1/2 study of HST-1011, an oral CBL-B inhibitor, alone and in combination with anti-PD1 in patients with advanced solid tumors, J Luke, Rachel E Sanborn, and See full list of authors in comments

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Neuroinflammation: A Modifiable Pathway Linking Obesity, Alzheimer's disease, and Depression., Maria Ly, Gary Z Yu, Ali Mian, Austin Cramer, Somayeh Meysami, David A Merrill, Amjad Samara, Sarah A Eisenstein, Tamara Hershey, Ganesh M Babulal, Eric J Lenze, John C Morris, Tammie L S Benzinger, and Cyrus A Raji

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Evolution in the treatment of gastroesophageal reflux disease over the last century: from a crural-centered to a lower esophageal sphincter-centered approach and back., Emily M Mackay and Brian E Louie

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A Phase Ib/II Study of Lenvatinib and Pembrolizumab in Advanced Endometrial Carcinoma (Study 111/KEYNOTE-146): Long-Term Efficacy and Safety Update., Vicky Makker, Carol Aghajanian, Allen L Cohn, Margarita Romeo, Raquel Bratos, Marcia S Brose, Mark Messing, Lea Dutta, Corina E Dutcus, Jie Huang, Emmett V Schmidt, Robert Orlowski, and Matthew H Taylor

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Persistence of patient-detected breast cancer over time: 1990-2019., Judith A Malmgren, Mary K Atwood, and Henry G Kaplan

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COVID-19 related change in breast cancer diagnosis, stage, treatment, and case volume: 2019-2021., Judith A Malmgren, Boya Guo, Mary K Atwood, Paula Hallam, Laura A Roberts, and Henry G Kaplan

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Plasma phosphocreatine (PC) as a predictive biomarker for immune checkpoint inhibition in patients with refractory metastatic colorectal cancer (mCRC): Analysis of the CCTG CO.26 trial., Lucy Xiaolu Ma, Hagen F Kennecke, and See full list of authors in comments

Plasma arginine as a candidate predictive biomarker for response to immune checkpoint inhibition (ICI) in metastatic colorectal cancer (mCRC): Analysis of the CCTG CO.26 trial, LX Ma, H Kennecke, and See all authors in comments

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Structural surfaceomics reveals an AML-specific conformation of integrin β, Kamal Mandal, Gianina Wicaksono, Clinton Yu, Jarrett J Adams, Michael R Hoopmann, William C Temple, Adila Izgutdina, Bonell Patiño Escobar, Maryna Gorelik, Christian H Ihling, Matthew A Nix, Akul Naik, William H Xie, Juwita Hübner, Lisa A Rollins, Sandy M Reid, Emilio Ramos, Corynn Kasap, Veronica Steri, Juan Antonio Camara Serrano, Fernando Salangsang, Paul Phojanakong, Melanie McMillan, Victor Gavallos, Andrew D Leavitt, Aaron C Logan, Cliona M Rooney, Justin Eyquem, Andrea Sinz, Benjamin J Huang, Elliot Stieglitz, Catherine C Smith, Robert L Moritz, Sachdev S Sidhu, Lan Huang, and Arun P Wiita

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Precision nephrology identified tumor necrosis factor activation variability in minimal change disease and focal segmental glomerulosclerosis., Laura H Mariani, Sean Eddy, Fadhl M AlAkwaa, Phillip J McCown, Jennifer L Harder, Viji Nair, Felix Eichinger, Sebastian Martini, Adebowale D Ademola, Vincent Boima, Heather N Reich, Jamal El Saghir, Bradley Godfrey, Wenjun Ju, Emily C Tanner, Virginia Vega-Warner, Noel L Wys, Sharon G Adler, Gerald B Appel, Ambarish Athavale, Meredith A Atkinson, Serena M Bagnasco, Laura Barisoni, Elizabeth Brown, Daniel C Cattran, Gaia M Coppock, Katherine M Dell, Vimal K Derebail, Fernando C Fervenza, Alessia Fornoni, Crystal A Gadegbeku, Keisha L Gibson, Laurence A Greenbaum, Sangeeta R Hingorani, Michelle A Hladunewich, Jeffrey B Hodgin, Marie C Hogan, Lawrence B Holzman, J Ashley Jefferson, Frederick J Kaskel, Jeffrey B Kopp, Richard A Lafayette, Kevin V Lemley, John C Lieske, Jen-Jar Lin, Rajarasee Menon, Kevin E Meyers, Patrick H Nachman, Cynthia C Nast, Michelle M O'Shaughnessy, Edgar A Otto, Kimberly J Reidy, Kamalanathan K Sambandam, John R Sedor, Christine B Sethna, Pamela Singer, Tarak Srivastava, Cheryl L Tran, Katherine Tuttle, Suzanne M Vento, Chia-Shi Wang, Akinlolu O Ojo, Dwomoa Adu, Debbie S Gipson, Howard Trachtman, and Matthias Kretzler

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Hyper-Dependence on NHEJ Enables Synergy Between DNA-PK Inhibitors and Low-Dose Doxorubicin in Leiomyosarcoma., Adrián Mariño-Enríquez, Jan Philipp Novotny, Doga C Gulhan, Isabella Klooster, Antuan V Tran, Macy Kasbo, Meijun Z Lundberg, Wen-Bin Ou, Derrick L Tao, Daniel F Pilco-Janeta, Victor Y Mao, Frank T Zenke, Brittaney A Leeper, Prafulla C Gokhale, Glenn S Cowley, Laurence H Baker, Karla V Ballman, David E Root, Joachim Albers, Peter J Park, Suzanne George, and Jonathan A Fletcher

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Pirtobrutinib after a Covalent BTK Inhibitor in Chronic Lymphocytic Leukemia., Anthony R Mato, Jennifer A Woyach, Jennifer R Brown, Paolo Ghia, Krish Patel, Toby A Eyre, Talha Munir, Ewa Lech-Maranda, Nicole Lamanna, Constantine S Tam, Nirav N Shah, Catherine C Coombs, Chaitra S Ujjani, Bita Fakhri, Chan Y Cheah, Manish R Patel, Alvaro J Alencar, Jonathon B Cohen, James N Gerson, Ian W Flinn, Shuo Ma, Deepa Jagadeesh, Joanna M Rhodes, Francisco Hernandez-Ilizaliturri, Pier L Zinzani, John F Seymour, Minna Balbas, Binoj Nair, Paolo Abada, Chunxiao Wang, Amy S Ruppert, Denise Wang, Donald E Tsai, William G Wierda, and Wojciech Jurczak

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Operational Ontology for Oncology (O3) - A Professional Society Based, Multi-Stakeholder, Consensus Driven Informatics Standard Supporting Clinical and Research use of "Real -World" Data from Patients Treated for Cancer: Operational Ontology for Radiation Oncology., C S Mayo, M U Feng, K K Brock, R Kudner, P Balter, J C Buchsbaum, A Caissie, E Covington, E C Daugherty, A L Dekker, C D Fuller, A L Hallstrom, D S Hong, J C Hong, S C Kamran, E Katsoulakis, J Kildea, A V Krauze, J J Kruse, T McNutt, M Mierzwa, A Moreno, J R Palta, R Popple, T G Purdie, Susan L Richardson, G C Sharp, S Shiraishi, L Tarbox, A M Venkatesan, A Witztum, K E Woods, J Yao, K Farahani, S Aneja, P E Gabriel, L Hadjiiski, D Ruan, J H Siewerdsen, S Bratt, M Casagni, S Chen, J Christodouleas, A DiDonato, J Hayman, R Kapoor, S Kravitz, S Sebastian, M Von Siebenthal, and Y Xiao

Neoadjuvant HER2-targeted Therapy +/- Immunotherapy with Pembrolizumab (neoHIP): An Open Label Randomized Phase II Trial, H McArthur, David B. Page, and See all authors in comments

A Single Arm Phase 2 Study of Peri-Operative Immune Checkpoint Inhibition and Cryoablation in Women With Hormone Receptor-Negative, HER2-Negative Early Stage/Resectable Breast Cancer, H McArthur, David Page, and See full list of authors in comments

Neoadjuvant HER2-targeted Therapy +/- Immunotherapy with Pembrolizumab (neoHIP): An Open Label Randomized Phase II Trial, H McArthur, David Page, and See full list of authors in comments

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Missed Opportunities: the Timing and Frequency of Screening Colonoscopy in Patients That Develop Esophageal Adenocarcinoma., Sarah C McKay, Melissa L DeSouza, Christy M Dunst, Kevin M Reavis, Daniel Davila Bradley, and Steven R DeMeester

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Missed Opportunities: the Timing and Frequency of Screening Colonoscopy in Patients That Develop Esophageal Adenocarcinoma., Sarah C McKay, Melissa L DeSouza, Christy M Dunst, Kevin M Reavis, Daniel Davila Bradley, and Steven R DeMeester

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Tumor differentiation impacts response to neoadjuvant therapy and survival in patients with esophageal adenocarcinoma., Sarah C McKay, Brian Louie, Daniela Molena, Weston G Andrews, Thomas Boerner, Wayne L Hofstetter, Jonathan Yeung, Gail E Darling, Ahmed Sharata, Christian G Peyre, Colin Dunn, John C Lipham, Horia Marginean, and Steven R DeMeester

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Safety of Extending Implanted Vascular Access Device Maintenance Flush Frequency., Monica McManus, Mary Jo Sarver, Elizabeth Ser, and Kelle Rene Gross

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Myeloid MyD88 restricts CD8+ T cell response to radiation therapy in pancreatic cancer, Terry R Medler, Tiffany Blair, Alejandro F Alice, Alexa K Dowdell, Brian D. Piening, Marka R Crittenden, and Michael J. Gough

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Myeloid MyD88 restricts CD8, Terry R Medler, Tiffany C Blair, Alejandro F Alice, Alexa K Dowdell, Brian D Piening, Marka R Crittenden, and Michael J Gough

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Tumor resident memory CD8 T cells and concomitant tumor immunity develop independently of CD4 help., Terry R Medler, Gwen Kramer, Shelly Bambina, Andrew J Gunderson, Alejandro Alice, Tiffany Blair, Lauren Zebertavage, Thomas Duhen, Rebekka Duhen, Kristina Young, Marka R Crittenden, and Michael J Gough

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Muscle mass cross-sectional area is associated with survival outcomes in malignant pleural disease related to lung cancer., Austin M Meggyesy, Candice L. Wilshire, Shu-Ching Chang, Jed A Gorden, and Christopher R Gilbert

Characterizing cancer’s dark matter, short-lived proteins, and defective ribosomal products, presented by cancer and contained in the DPV-001 cancer vaccine, R Meng, Will Redmond, Carlo Bifulco, Rachel Sanborn, RB Bell, Walter Urba, Rom Leidner, Brian Piening, Bernard Fox, and See full list of authors in comments

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Cobimetinib Plus Vemurafenib in Patients With Solid Tumors With, Funda Meric-Bernstam, Michael Rothe, Pam K Mangat, Elizabeth Garrett-Mayer, Rodolfo Gutierrez, Eugene R Ahn, Timothy L Cannon, Steven Powell, John C Krauss, Christopher M Reynolds, Margaret von Mehren, Deepti Behl, Carmen J Calfa, Herbert L Duvivier, Henry G Kaplan, Michael B Livingston, Manish R Sharma, Walter Urba, Gina N Grantham, Dominique C Hinshaw, Abigail Gregory, Susan Halabi, and Richard L Schilsky

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Novel TCF4:TCF12 heterodimer inhibits glioblastoma growth., Svetlana A Mikheeva, Cory C Funk, Philip J Horner, Robert C Rostomily, and Andrei M Mikheev

Abstract CT226: Crizotinib (C) in patients (pts) with solid tumors with MET amplification (amp) or mutation (mut): Results from the Targeted Agent and Profiling Utilization Registry (TAPUR) Study, Kathryn F. Mileham, Rom Leidner, and See full list of authors in comments

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Breast Cancer Screening, Diagnosis, and Surgery during the Pre- and Peri-pandemic: Experience of Patients in a Statewide Health Information Exchange., Zheng Z Milgrom, Daniel P Milgrom, Yan Han, Siu L Hui, David A Haggstrom, Carla S Fisher, and Eneida A Mendonca

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ASO Author Reflections: Patient Interest and Outcomes with Simultaneous Symmetry Procedures in Oncoplastic Breast-Conserving Surgery., Janelle-Cheri Millen and Janie Grumley

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Simultaneous Symmetry Procedure in Patients Undergoing Oncoplastic Breast-Conserving Surgery: An Evaluation of Patient Desire and Revision Rates., Janelle-Cheri Millen, Katherine M Jackson, Stacey Stern, Javier I Orozco, Crystal E Fancher, and Janie Grumley

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ASO Visual Abstract: Simultaneous Symmetry Procedure in Patients Undergoing Oncoplastic Breast-Conserving Surgery: An Evaluation of Patient Desire and Revision Rates., Janelle-Cheri Millen, Katherine Jackson, Stacey L Stern, Javier I J Orozco, Crystal E Fancher, and Janie Grumley

Simultaneous identification of KRAS mutation-carrying multiple neoepitopes by differential ion mobility-assisted targeted-mass spectrometry, Y Minegishi, Eric Tran, Will Redmond, Brian Piening, Bernard Fox, and See all authors in comments

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Multicenter International Study of the Consensus Immunoscore for the Prediction of Relapse and Survival in Early-Stage Colon Cancer., Bernhard Mlecnik, Alessandro Lugli, Gabriela Bindea, Florence Marliot, Carlo Bifulco, Jiun-Kae Jack Lee, Inti Zlobec, Tilman T Rau, Martin D Berger, Iris D Nagtegaal, Elisa Vink-Börger, Arndt Hartmann, Carol I Geppert, Julie Kolwelter, Susanne Merkel, Robert Grützmann, Marc Van den Eynde, Anne Jouret-Mourin, Alex Kartheuser, Daniel Léonard, Christophe Remue, Julia Wang, Prashant Bavi, Michael H A Roehrl, Pamela S Ohashi, Linh T Nguyen, SeongJun Han, Heather L MacGregor, Sara Hafezi-Bakhtiari, Bradly G Wouters, Giuseppe V Masucci, Emilia K Andersson, Eva Zavadova, Michal Vocka, Jan Spacek, Lubos Petruzelka, Bohuslav Konopasek, Pavel Dundr, Helena Skalova, Kristyna Nemejcova, Gerardo Botti, Fabiana Tatangelo, Paolo Delrio, Gennaro Ciliberto, Michele Maio, Luigi Laghi, Fabio Grizzi, Tessa Fredriksen, Bénédicte Buttard, Lucie Lafontaine, Pauline Maby, Amine Majdi, Assia Hijazi, Carine El Sissy, Amos Kirilovsky, Anne Berger, Christine Lagorce, Christopher Paustian, Carmen Ballesteros-Merino, Jeroen Dijkstra, Carlijn van de Water, Shannon van Lent-van Vliet, Nikki Knijn, Ana-Maria Mușină, Dragos-Viorel Scripcariu, Boryana Popivanova, Mingli Xu, Tomonobu Fujita, Shoichi Hazama, Nobuaki Suzuki, Hiroaki Nagano, Kiyotaka Okuno, Toshihiko Torigoe, Noriyuki Sato, Tomohisa Furuhata, Ichiro Takemasa, Prabhu Patel, Hemangini H Vora, Birva Shah, Jayendrakumar B Patel, Kruti N Rajvik, Shashank J Pandya, Shilin N Shukla, Yili Wang, Guanjun Zhang, Yutaka Kawakami, Francesco M Marincola, Paolo A Ascierto, Bernard A Fox, Franck Pagès, and Jérôme Galon

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Health-related quality of life with pembrolizumab or placebo plus chemotherapy with or without bevacizumab for persistent, recurrent, or metastatic cervical cancer (KEYNOTE-826): a randomised, double-blind, placebo-controlled, phase 3 trial., Bradley J Monk, Krishnansu S Tewari, Coraline Dubot, M Valeria Caceres, Kosei Hasegawa, Ronnie Shapira-Frommer, Pamela Salman, Eduardo Yañez, Mahmut Gümüş, Mivael Olivera Hurtado de Mendoza, Vanessa Samouëlian, Vincent Castonguay, Alexander Arkhipov, Cumhur Tekin, Kan Li, Allison Martin Nguyen, Matthew J Monberg, Nicoletta Colombo, and Domenica Lorusso

Peripheral and tissue persistence of agenT-797, an allogeneic iNKT cell-based cell therapy for the treatment of cancer, J Moon, Rachel Sanborn, Dave Hoon, and See full list of authors in comments

A phase 1/1b study of the tumor-activated IL-2 prodrug WTX-124 alone or in combination with pembrolizumab in patients with immunotherapy-sensitive locally advanced or metastatic solid tumors, JC Moser, Brendan Curti, and See full list of authors in comments

PD-1 expression on tumor-infiltrating T-lymphocytes as determinant of the head and neck cancer tumor immune microenvironment rather than anatomical site, T Muijlwijk, Bernard Fox, and See full list of authors in comments

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Breast Conservation Surgery and Mastectomy have Similar Locoregional Recurrence Following Neoadjuvant Chemotherapy: Results from 1,462 Patients on the Prospective, Randomized I-SPY2 Trial., Rita A Mukhtar, Harrison Chau, Hannah Woriax, Mara Piltin, Gretchen Ahrendt, Julia Tchou, Hongmei Yu, Qian Ding, Catherine Lu Dugan, Jori Sheade, Angelena Crown, Michael Carr, Jasmine Wong, Jennifer Son, Rachel Yang, Theresa Chan, Alicia Terando, Michael Alvarado, Cheryl Ewing, Jennifer Tonneson, Nina Tamirisa, Rebekah Gould, Puneet Singh, Constantine Godellas, Kelsey Larson, Akiko Chiba, Roshni Rao, Candice Sauder, Lauren Postlewait, Marie Catherine Lee, William Fraser Symmans, Laura J Esserman, Judy C Boughey, and ISPY-2 Locoregional Working Group

Localized Contrastive and Attention Based Multiple Instance Learning for Automatic Staging of Histopathology Images., N Naik, Carlo Bifulco, Brian Piening, and See full list of authors in comments

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Integrated Hospital- and Home-Based Palliative Care for Cancer Patients in Vietnam: People-Centered Outcomes., Viet Nguyen, Quach Thanh Khanh, Mevhibe Hocaoglu, Hoang Thi Mong Huyen, Dang Huy Quoc Thinh, and Eric L Krakauer

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Building the foundation for a community-generated national research blueprint for inherited bleeding disorders: research priorities for ultra-rare inherited bleeding disorders., Diane Nugent, Suchitra S Acharya, Kimberly J Baumann, Camille Bedrosian, Rebecca Bialas, Kai Brown, Deya Corzo, Amar Haidar, Catherine P M Hayward, Peter Marks, Marzia Menegatti, Margaret E Miller, Kate Nammacher, Roberta Palla, Skye Peltier, Rajiv K Pruthi, Michael Recht, Benny Sørensen, Michael Tarantino, Alisa S Wolberg, and Amy D Shapiro

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Building the foundation for a community-generated national research blueprint for inherited bleeding disorders: research priorities for ultra-rare inherited bleeding disorders., Diane Nugent, Suchitra S Acharya, Kimberly J Baumann, Camille Bedrosian, Rebecca Bialas, Kai Brown, Deya Corzo, Amar Haidar, Catherine P M Hayward, Peter Marks, Marzia Menegatti, Margaret E Miller, Kate Nammacher, Roberta Palla, Skye Peltier, Rajiv K Pruthi, Michael Recht, Benny Sørensen, Michael Tarantino, Alisa S Wolberg, and Amy D Shapiro

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A Plain Language Summary of Results from the GARNET Study of Dostarlimab in Patients with Endometrial Cancer., Ana Oaknin, Lucy Gilbert, Anna V Tinker, Jubilee Brown, Cara Mathews, Joshua Press, Renaud Sabatier, David M O'Malley, Vanessa Samouelian, Valentina Boni, Linda Duska, Sharad Ghamande, Prafull Ghatage, Rebecca Kristeleit, Charles Leath, Yuping Dong, Jennifer Veneris, and Bhavana Pothuri

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Reconstructing the Mandible: Jaw-In-A-Day: Where We Were, Where We Are, and the Future., David Omole, Baber Khatib, Ashish A Patel, Allen Cheng, Andrew Salama, Lawrence E Brecht, and David L Hirsch

Molecular features associated with long survival on tebentafusp in previously untreated metastatic uveal melanoma in a phase 3 trial, M Orloff, Brendan Curti, and See full list of authors in comments

A phase II study of nivolumab plus ipilimumab and androgen receptor antagonist bicalutamide to stimulate thymic T cell generation in HER2-negative metastatic breast cancer. Page D. SABCS Annual Meeting; 2023 December 7; San Antonio, TX., David Page

Association of pathologic complete response with the 27-gene IO score and week 3 IOpath response following neoadjuvant pembrolizumab +/- intralymphatic cytokines in the neoIRX trial. Page D. SABCS Annual Meeting; 2023 December 6; San Antonio, TX., David Page

Novel Directions of ADCs in Breast Cancer. Binaytara Foundation Highlights from SABCS 2022; 2023 January 20; Seattle, WA., David B Page

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A phase Ib trial of pembrolizumab plus paclitaxel or flat-dose capecitabine in 1st/2nd line metastatic triple-negative breast cancer., David B Page, Joanna Pucilowska, Brie Chun, Isaac Kim, Katherine Sanchez, Nicole Moxon, Staci Mellinger, Yaping Wu, Yoshinobu Koguchi, Valerie Conrad, William L Redmond, Maritza Martel, Zhaoyu Sun, Mary B Campbell, Alison Conlin, Anupama Acheson, Reva Basho, Philomena McAndrew, Mary El-Masry, Dorothy Park, Laura Bennetts, Robert S Seitz, Tyler J Nielsen, Kimberly McGregor, Venkatesh Rajamanickam, Brady Bernard, Walter J Urba, and Heather L McArthur

A phase II study of nivolumab plus ipilimumab and androgen receptor antagonist bicalutamide to stimulate thymic T cell generation in HER2-negative metastatic breast cancer, David Page, Allison Conlin, Sasha Stanton, Walter Urba, Will Redmond, and See full list of authors in comments

Association of pathologic complete response with the 27-gene IO score and week 3 IOpath response following neoadjuvant pembrolizumab +/- intralymphatic cytokines in the neoIRX trial, David Page, Will Redmond, Allison Conlin, S Stanton, and See full list of authors in comments

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Multi-institutional validation of a radiomics-based artificial intelligence method for predicting response to PD-1/PD-L1 immune checkpoint inhibitor (ICI) therapy in stage IV NSCLC, RB Parikh, Brendan Curti, and See full list of authors in comments

Phase 1/2 study of the bispecific 4–1BB and PD-L1 antibody INBRX-105 alone and in combination with pembrolizumab in select solid tumors, JC Park, Rachel Sanborn, and See full list of authors in comments

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Management of infusion-related reactions (IRRs) in patients receiving amivantamab in the CHRYSALIS study., Keunchil Park, Joshua K Sabari, Eric B Haura, Catherine A Shu, Alexander Spira, Ravi Salgia, Karen L Reckamp, Rachel E Sanborn, Ramaswamy Govindan, Joshua M Bauml, Joshua C Curtin, John Xie, Amy Roshak, Patricia Lorenzini, Dawn Millington, Meena Thayu, Roland E Knoblauch, and Byoung Chul Cho

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268 - Outpatient CAR T Cell Therapy Is Safe and Feasible in Patients with Lymphoma Treated in Non-University Medical Centers: A Multicenter, Retrospective Analysis, Krish Patel, Megumi Bailey, Neil Bailey, Suzanne Fanning, Kayla Gulley, Jens Frisvold, Sonia Glennie, Vanessa Dunleavy, Sandra Benitez-Kruidenier, Julia Parker, Shannon Williams, Suzan Sullivan, Carol Dean, Heidi Hohmann, Chiachun Lu, Catherine Tierney, Grace Mun, Daniel N Egan, and James Essell

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CT132 / 20 - Trial in progress: A phase 1/2 study of ASP1570, a novel inhibitor of DGKζ, in participants with locally advanced or metastatic solid tumors who have progressed on, or are ineligible for, all available standard therapies, Manish R. Patel, David J Park, and See full list of authors in comments

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Screening for occult cancer after unprovoked venous thromboembolism: Assessing the current literature and future directions., Sarah S Patel, Derrick Tao, Hannah S McMurry, and Joseph J Shatzel

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Incidence, demographics, and survival of malignant hemangioendothelioma in the United States., Kelly G Paulson, Vinod Ravi, Brian P Rubin, Min Park, Elizabeth T Loggers, Lee D Cranmer, and Michael J Wagner

Multi-parametric assessment of the immune response to a trio immunotherapy in patients with recurrent or metastatic head and neck squamous cell carcinoma, C Paustian, Matthew Taylor, Will Redmond, B Bernard, RB Bell, Carlo Bifulco, Brian Piening, Walter Urba, Bernard Fox, Rom Leidner, and See full list of authors in comments

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Using Aromatherapy to Improve Nighttime Comfort in Hospitalized Patients With Cancer: A Pilot Study., Leah Phillips, Marwa Kilani, Sherri Mendelson, and Ross J Bindler

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Does Aromatherapy Improve Nighttime Comfort for Hospitalized Oncology Patients: A Pilot Study, Leah Phillips, Sherri Mendelson, Marwa Kilani, and Ross Bindler

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Correction to: Clinical characteristics associated with falls in patients with non-metastatic castration-resistant prostate cancer treated with apalutamide., YaoYao Pollock, Matthew R Smith, Fred Saad, Simon Chowdhury, Stéphane Oudard, Boris Hadaschik, David Olmos, Ji Youl Lee, Hiroji Uemura, Amitabha Bhaumik, Anil Londhe, Brendan Rooney, Sabine D Brookman-May, Peter De Porre, Suneel D Mundle, and Eric J Small

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Abstract 6764: Multi-parametric comparison of scRNA-seq with CITE-seq and ultrahigh-plex spatial phenotyping of proteins in FFPE head and neck tumor biopsies: An opportunity to generate uniquely comprehensive multi-omic single cell datasets to investigate the tumor microenvironment, Aditya Pratapa, Brady Bernard, Brian D. Piening, Rom Leidner, Bernard A Fox, and See all authors in comments

The role of dendritic cells in radiation-induced immune responses., A Preet Kaur, A Alice, MR Crittenden, and MJ Gough

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Toward structuring real-world data: Deep learning for extracting oncology information from clinical text with patient-level supervision., Sam Preston, Mu Wei, Rajesh Rao, Robert Tinn, Naoto Usuyama, Michael Lucas, Yu Gu, Roshanthi Weerasinghe, Soohee Lee, Brian D. Piening, Paul Tittel, Naveen Valluri, Tristan Naumann, Carlo Bifulco, and Hoifung Poon

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Neoantigen-targeted CD8+ T cell responses with PD-1 blockade therapy, Cristina Puig-Saus, Barbara Sennino, Songming Peng, Clifford L Wang, Zheng Pan, Benjamin Yuen, Bhamini Purandare, Duo An, Boi B Quach, Diana Nguyen, Huiming Xia, Sameeha Jilani, Kevin Shao, Claire McHugh, John Greer, Phillip Peabody, Saparya Nayak, Jonathan Hoover, Sara Said, Kyle Jacoby, Olivier Dalmas, Susan P Foy, Andrew Conroy, Michael C Yi, Christine Shieh, William Lu, Katharine Heeringa, Yan Ma, Shahab Chizari, Melissa J Pilling, Marc Ting, Ramya Tunuguntla, Salemiz Sandoval, Robert Moot, Theresa Hunter, Sidi Zhao, Justin D Saco, Ivan Perez-Garcilazo, Egmidio Medina, Agustin Vega-Crespo, Ignacio Baselga-Carretero, Gabriel Abril-Rodriguez, Grace Cherry, Deborah J Wong, Jasreet Hundal, Bartosz Chmielowski, Daniel E Speiser, Michael T Bethune, Xiaoyan R Bao, Alena Gros, Obi L Griffith, Malachi Griffith, James R Heath, Alex Franzusoff, Stefanie J Mandl, and Antoni Ribas

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A Network Landscape of HPVOPC Reveals Methylation Alterations as Significant Drivers of Gene Expression via an Immune-Mediated GPCR Signal., Jesse R Qualliotine, Takuya Nakagawa, Sara Brin Rosenthal, Sayed Sadat, Carmen Ballesteros-Merino, Guorong Xu, Adam Mark, Art Nasamran, J Silvio Gutkind, Kathleen M Fisch, Theresa Guo, Bernard A Fox, Zubair Khan, Alfredo A Molinolo, and Joseph A Califano

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Visceral and Subcutaneous Abdominal Fat Predict Brain Volume Loss at Midlife in 10,001 Individuals., Cyrus A Raji, Somayeh Meysami, Sam Hashemi, Saurabh Garg, Nasrin Akbari, Ahmed Gouda, Yosef Gavriel Chodakiewitz, Thanh Duc Nguyen, Kellyann Niotis, David A Merrill, and Rajpaul Attariwala

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Cancer stem cell assay-guided chemotherapy improves survival of patients with recurrent glioblastoma in a randomized trial., Tulika Ranjan, Soma Sengupta, Michael J Glantz, Richard M Green, Alexander Yu, Dawit Aregawi, Rekha Chaudhary, Ricky Chen, Mario Zuccarello, Christine Lu-Emerson, Hugh D Moulding, Neil Belman, Jon Glass, Aaron Mammoser, Mark Anderson, Jagan Valluri, Nicholas Marko, Jason Schroeder, Steven Jubelirer, Frances Chow, Pier Paolo Claudio, Anthony M Alberico, Seth T Lirette, Krista L Denning, and Candace M Howard