The Cancer Institute is a leader in cutting-edge treatments. Using a truly multidisciplinary approach, patients have access to advanced diagnostics, minimally invasive surgical interventions, and personalized genomic and immune-oncologic treatment options. Our team of cancer specialists – many of whom completed fellowships and specialty training at prestigious academic centers – offers comprehensive services for individuals with a cancer diagnosis.

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Submissions from 2022

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For Ethical Fundraising from Patients, Respect them as Partners., Brendan Curti

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Chapter 72: Cancer of the Skin, Brendan Curti, Sancy Leachman, and Walter Urba

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Intratumoral oncolytic virus V937 plus ipilimumab in patients with advanced melanoma: the phase 1b MITCI study., Brendan Curti, Jon Richards, John R Hyngstrom, Gregory A Daniels, Mark Faries, Lynn Feun, Kim A Margolin, Sigrun Hallmeyer, Mark Grose, Yiwei Zhang, Anlong Li, and Robert H I Andtbacka

Open-label, phase 2, multicenter study of lasofoxifene (LAS) combined with abemaciclib (Abema) for treating pre- and postmenopausal women with locally advanced or metastatic ER+/HER2− breast cancer and an ESR1 mutation after progression on prior therapies., Senthil Damodaran, Paul V. Plourde, Halle CF Moore, Ian Churchill Anderson, and David Jay Portman

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Dose escalation of davoceticept, a conditional CD28 costimulator and dual checkpoint inhibitor, in advanced malignancies (NEON-1), Diwakar Davar, Rachel E Sanborn, and See full list of authors in comments

Phase 1 study of SEA-TGT, a human, nonfucosylated monoclonal antibody directed to TIGIT with enhanced immune effector function, in patients with advanced malignancies (SGNTGT-001, trial in progress), D Davar, Rachel E Sanborn, and See full list of authors in comments

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The TP53 Database: transition from the International Agency for Research on Cancer to the US National Cancer Institute., Kelvin César de Andrade, Elaine E Lee, Elise M Tookmanian, Chimene A Kesserwan, James J Manfredi, Jessica N Hatton, Jennifer K Loukissas, Jiri Zavadil, Lei Zhou, Magali Olivier, Megan N Frone, Owais Shahzada, William J R Longabaugh, Christian P Kratz, David Malkin, Pierre Hainaut, and Sharon A Savage

PIVOT IO 001: First disclosure of efficacy and safety of bempegaldesleukin (BEMPEG) plus nivolumab (NIVO) vs NIVO monotherapy in advanced melanoma (MEL), A Diab, Brendan Curti, and See all authors in comments

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Comparison of health-care utilization and expenditures for minimally invasive vs. open colectomy for benign disease., Sarah E Diaz, Yongjin F Lee, Amir Bastawrous, I-Fan Shih, Shih-Hao Lee, Yanli Li, and Robert K Cleary

546 A phase I dose escalation study of STEMVAC, a multi-antigen, multi-epitope Th1 selective plasmid-based vaccine, targeting stem cell associated proteins in patients with advanced breast cancer, Mary Disis, Sasha Stanton, and See all authors in comments

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Automatic Patient Matching for Genome-Guided Adoptive Cell Immunotherapy Trials at a Large Health System, Alexa K Dowdell, Tucker Bower, Benjamin Cosgrove, Roshanthi Weerasinghe, Ann Vita, Brian D. Piening, Carlo Bifulco, Eric Tran, and Rom Leidner

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Latinx attitudes, barriers, and experiences with genetic counseling and testing: A systematic review., Heather A Dron, Daiana Bucio, Jennifer L Young, Holly K Tabor, and Mildred K Cho

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OX40 agonist stimulation increases and sustains humoral and cell-mediated responses to SARS-CoV-2 protein and saRNA vaccines., Rebekka Duhen, Michael Beymer, Shawn M. Jensen, Srinivas Abbina, Suraj Abraham, Nikita Jain, Anitha Thomas, Andrew J Geall, Hong-Ming Hu, Bernard A Fox, and Andrew D Weinberg

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PD-1 and ICOS co-expression identifies tumor-reactive CD4 T cells in human solid tumors., Rebekka Duhen, Olivier Fesneau, Kimberly Samson, Alexandra K Frye, Michael Beymer, Venkatesh Rajamanickam, David Ross, Eric Tran, Brady Bernard, Andrew D Weinberg, and Thomas Duhen

Aperçu de l’immunothérapie et défis de l’immuno-oncologie, T Duhen

PD-1 and ICOS co-expression identifies tumor-reactive CD4 T cells in human solid tumors, Thomas Duhen

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Prognostic significance of ethnicity and age in advanced stage epithelial ovarian cancer: An NRG oncology/gynecologic oncology group study., Nefertiti C duPont, Danielle Enserro, Mark F Brady, Katherine Moxley, Joan L Walker, Casey Cosgrove, Kristin Bixel, Krishnansu S Tewari, Premal Thaker, Andrea E Wahner Hendrickson, Stephen Rubin, Keiichi Fujiwara, A Catherine Casey, John Soper, Robert A Burger, and Bradley J Monk

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Prognostic significance of ethnicity and age in advanced stage epithelial ovarian cancer: An NRG oncology/gynecologic oncology group study., Nefertiti C duPont, Danielle Enserro, Mark F Brady, Katherine Moxley, Joan L Walker, Casey Cosgrove, Kristin Bixel, Krishnansu S Tewari, Premal Thaker, Andrea E Wahner Hendrickson, Stephen Rubin, Keiichi Fujiwara, A Catherine Casey, John Soper, Robert A Burger, and Bradley J Monk

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The Emergence of Virtual Tumor Boards in Neuro-Oncology: Opportunities and Challenges., Chukwuyem Ekhator, Santosh Kesari, Ramya Tadipatri, Ekokobe Fonkem, and Jai Grewal

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Survival and Toxicities after, Erica C Emmons, Steven Bishay, Liping Du, Henry Krebs, Ripal T Gandhi, Zachary S Collins, Ryan O'Hara, Nabeel M Akhter, Eric A Wang, Christopher Grilli, Jayson S Brower, Shannon R Peck, Michael Petroziello, Ahmed K Abdel Aal, Jafar Golzarian, Andrew S Kennedy, Lea Matsuoka, Daniel Y Sze, and Daniel B Brown

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Epigenetic Signatures Predict Pathologic Nodal Stage in Breast Cancer Patients with Estrogen Receptor-Positive, Clinically Node-Positive Disease., Miquel Ensenyat-Mendez, Dennis Rünger, Javier I Orozco, Julie Le, Jennifer L Baker, Joanne Weidhaas, Diego M Marzese, and Maggie L DiNome

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Real-world burden of chemotherapy-induced myelosuppression in patients with small cell lung cancer: a retrospective analysis of electronic medical data from community cancer care providers., Robert S. Epstein, Roshanthi Weerasinghe, Amy S. Parrish, JoAnn Krenitsky, Rachel E Sanborn, and Tehseen Salimi

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T Cells Engineered to Express Immunoreceptors Targeting the Frequently Expressed Medullary Thyroid Cancer Antigens Calcitonin, CEA, and RET M918T., Timothy A Erickson, Yi-Ping Shih, Joseph Fass, Myungkyu Jang, and Eric Tran

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How I treat brain metastases of melanoma., Z Eroglu, T O Topcu, H M Yu, and K A Margolin

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ACR Appropriateness Criteria® Management of Liver Cancer: 2022 Update., Expert Panel on Interventional Radiology, Erica M Knavel Koepsel, Amanda R Smolock, Jason W Pinchot, Charles Y Kim, Osmanuddin Ahmed, Murthy R K Chamarthy, Elizabeth M Hecht, Gloria L Hwang, David E Kaplan, Join Y Luh, Jorge A Marrero, Eric J Monroe, George A Poultsides, Matthew J Scheidt, and Eric J Hohenwalter

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Dental management in head and neck cancers: from intensity-modulated radiotherapy with photons to proton therapy., Sabah Falek, Rajesh Regmi, Joel Herault, Melanie Dore, Anthony Vela, Pauline Dutheil, Cyril Moignier, Pierre-Yves Marcy, Julien Drouet, Arnaud Beddok, Noah E Letwin, Joel Epstein, Upendra Parvathaneni, and Juliette Thariat

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ASO Visual Abstract: Landmark Series-Addressing Disparities in Breast Cancer Screening: New Recommendations for Black Women., Oluwadamilola M Fayanju, Christine E Edmonds, Sylvia A Reyes, Cletus Arciero, Vivian J Bea, Angelena Crown, and Kathie-Ann Joseph

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The Landmark Series-Addressing Disparities in Breast Cancer Screening: New Recommendations for Black Women., Oluwadamilola M Fayanju, Christine E Edmonds, Sylvia A Reyes, Cletus Arciero, Vivian J Bea, Angelena Crown, and Kathie-Ann Joseph

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A Phase II, Single-arm Trial of Sunitinib and Erlotinib in Advanced Renal Cell Carcinoma., Zizhen Feng, Brendan Curti, David I Quinn, John M Strother, Zunqiu Chen, Rebecca Agnor, Tomasz M Beer, and Christopher W Ryan

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Phase II Randomized Trial of Transoral Surgery and Low-Dose Intensity Modulated Radiation Therapy in Resectable p16+ Locally Advanced Oropharynx Cancer: An ECOG-ACRIN Cancer Research Group Trial (E3311)., Robert L Ferris, Yael Flamand, Gregory S Weinstein, Shuli Li, Harry Quon, Ranee Mehra, Joaquin J Garcia, Christine H Chung, Maura L Gillison, Umamaheswar Duvvuri, Bert W O'Malley, Enver Ozer, Giovana R Thomas, Wayne M Koch, Neil D Gross, Richard Bryan Bell, Nabil F Saba, Miriam Lango, Eduardo Méndez, and Barbara Burtness

Identification of a subset of tumor-reactive CD8 TILs expressing NKG2A in HNSCC and CRC., O Fesneau, Thomas Duhen, and See full list of authors in comments

Identification of a subset of tumor-reactive CD8 TIL expressing NKG2A in HNSCC and CRC, O Fesneau, K Samson, V Rajamanickam, D Ross, and Thomas Duhen

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Roadmap on plasticity and epigenetics in cancer., Jasmine Foo, David Basanta, Russell C Rockne, Carly Strelez, Curran Shah, Kimya Ghaffarian, Shannon M Mumenthaler, Kelly Mitchell, Justin D Lathia, David Frankhouser, Sergio Branciamore, Ya-Huei Kuo, Guido Marcucci, Robert Vander Velde, Andriy Marusyk, Sui Huang, Kishore Hari, Mohit Kumar Jolly, Haralampos Hatzikirou, Kamrine Poels, Mary Spilker, Blerta Shtylla, Mark Robertson-Tessi, and Alexander R A Anderson

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Observed Concordance of Prostate Lesions on MRI with MRI/Ultrasound Fusion Biopsy Results, Kelcie Foshag, Scott King, Chance Brock, and Abigail Cone

40 years of experiences moving science from the bench to 1st in human clinical trials of immunotherapy and gene therapy, Bernard Fox

A Vision for Personalizing Treatments to Overcome Cancer’s Escape Mechanisms and Improve Outcomes for Patients, Bernard Fox

A Vision to Cure More Patients with Cancer by Better Identifying the Impact of Treatment and Modifying Therapy Appropriately, Bernard Fox

Cancer Vaccines: A Phoenix Rising from the Ashes, Bernard Fox

Combining 10x scRNA-seq and 100 plex mIF: Too much data or complimentary technologies to examine what works, Bernard Fox

Complex Cancer Vaccines: An Approach to Induce Immunity Against Gastroesophageal Malignancies in 2022, Bernard Fox

Comprehensive Spatial Phenotyping: Mapping the Tumor Microenvironment at Scale, Bernard Fox

Immune Activating and Cancer Vaccine Technology, Bernard Fox

Overview of Immunotherapy and Challenges for Immuno-Oncology, Bernard Fox

Progress in Cellular Immunotherapy - It is not Just Mutations: A Vision into Combinations to Expect in 2023 and Beyond, Bernard Fox

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Non-viral precision T cell receptor replacement for personalized cell therapy., Susan P Foy, Kyle Jacoby, Daniela A Bota, Theresa Hunter, Zheng Pan, Eric Stawiski, Yan Ma, William Lu, Songming Peng, Clifford L Wang, Benjamin Yuen, Olivier Dalmas, Katharine Heeringa, Barbara Sennino, Andy Conroy, Michael T Bethune, Ines Mende, William White, Monica Kukreja, Swetha Gunturu, Emily Humphrey, Adeel Hussaini, Duo An, Adam J Litterman, Boi Bryant Quach, Alphonsus H C Ng, Yue Lu, Chad Smith, Katie M Campbell, Daniel Anaya, Lindsey Skrdlant, Eva Yi-Hsuan Huang, Ventura Mendoza, Jyoti Mathur, Luke Dengler, Bhamini Purandare, Robert Moot, Michael C Yi, Roel Funke, Alison Sibley, Todd Stallings-Schmitt, David Y Oh, Bartosz Chmielowski, Mehrdad Abedi, Yuan Yuan, Jeffrey A Sosman, Sylvia M Lee, Adam J Schoenfeld, David Baltimore, James R Heath, Alex Franzusoff, Antoni Ribas, Arati V Rao, and Stefanie J Mandl

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Correction: Interplay between soluble CD74 and macrophage-migration inhibitory factor drives tumor growth and influences patient survival in melanoma., Yasunari Fukuda, Matias A Bustos, Sung-Nam Cho, Jason Roszik, Suyeon Ryu, Victor M Lopez, Jared K Burks, Jeffrey E Lee, Elizabeth A Grimm, Dave S B Hoon, and Suhendan Ekmekcioglu

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Interplay between soluble CD74 and macrophage-migration inhibitory factor drives tumor growth and influences patient survival in melanoma., Yasunari Fukuda, Matias A Bustos, Sung-Nam Cho, Jason Roszik, Suyeon Ryu, Victor M Renteria-Lopez, Jared K Burks, Jeffrey E Lee, Elizabeth A Grimm, Dave Hoon, and Suhendan Ekmekcioglu

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Recommended phase 2 dose (RP2D) of HB-200 arenavirus-based cancer immunotherapies in patients with HPV16+ cancers., Siqing Fu, Rom Leidner, and Matthew H Taylor

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Differentiation of Subjective Cognitive Decline, Mild Cognitive Impairment, and Dementia Using qEEG/ERP-Based Cognitive Testing and Volumetric MRI in an Outpatient Specialty Memory Clinic., Aarthi S Ganapathi, Ryan M Glatt, Tess H Bookheimer, Emily S Popa, Morgan L Ingemanson, Casey J Richards, John F Hodes, Kyron P Pierce, Colby B Slyapich, Fatima Iqbal, Jenna Mattinson, Melanie G Lampa, Jaya M Gill, Ynez M Tongson, Claudia L Wong, Mihae Kim, Verna R Porter, Santosh Kesari, Somayeh Meysami, Karen J Miller, Jennifer E Bramen, David A Merrill, and Prabha Siddarth

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Organ Preservation in Patients With Rectal Adenocarcinoma Treated With Total Neoadjuvant Therapy., Julio Garcia-Aguilar, Sujata Patil, Marc J Gollub, Jin K Kim, Jonathan B Yuval, Hannah M Thompson, Floris S Verheij, Dana M Omer, Meghan Lee, Richard F Dunne, Jorge Marcet, Peter Cataldo, Blase Polite, Daniel O Herzig, David Liska, Samuel Oommen, Charles M Friel, Charles Ternent, Andrew L Coveler, Steven Hunt, Anita Gregory, Madhulika G Varma, Brian L Bello, Joseph C Carmichael, John Krauss, Ana Gleisner, Philip B Paty, Martin R Weiser, Garrett M Nash, Emmanouil Pappou, José G Guillem, Larissa Temple, Iris H Wei, Maria Widmar, Sabrina Lin, Neil H Segal, Andrea Cercek, Rona Yaeger, J Joshua Smith, Karyn A Goodman, Abraham J Wu, and Leonard B Saltz

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Management of the undescended testis in children: An American pediatric surgical association outcomes and evidence based practice committee systematic review., Robert L Gates, Julia Shelton, Karen A Diefenbach, Meghan Arnold, Shawn D St Peter, Elizabeth J Renaud, Mark B Slidell, Stig Sømme, Patricia Valusek, Gustavo A Villalona, Jarod P McAteer, Alana L Beres, Joanne Baerg, Rebecca M Rentea, Lorraine Kelley-Quon, Akemi L Kawaguchi, Yue-Yung Hu, Doug Miniati, Robert Ricca, and Robert Baird

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Label-free plasma proteomics for the identification of the putative biomarkers of oral squamous cell carcinoma., Shashyendra Singh Gautam, Raghwendra Pratap Singh, Kajal Karsauliya, Ashish Kumar Sonker, Panga Jaipal Reddy, Divya Mehrotra, Sameer Gupta, Sudhir Singh, Rashmi Kumar, and Sheelendra Pratap Singh

A Phase 1 Study of TAK-676, a Novel STING Agonist, Plus Pembrolizumab Following Radiation Therapy in Patients with Advanced Non–Small-Cell Lung Cancer (NSCLC), Triple-Negative Breast Cancer (TNBC), or Squamous-Cell Carcinoma of the Head and Neck (SCCHN), NK Gerber, DB Page, and See all authors in comments

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A phase 2 study of an off-the-shelf, multi-neoantigen vector (ADXS-503) in patients with metastatic non–small cell lung cancer either progressing on prior pembrolizumab or in the first-line setting., Gregory James Gerstner, Rachel E Sanborn, and See full list of authors in comments

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Verification of a Novel Minimally Invasive Device for the Isolation of Rare Circulating Tumor Cells (CTC) in Cancer Patients' Blood., Paul Friedrich Geus, Felix Hehnen, Sophia Krakowski, Klaus Lücke, Dave Hoon, Nikolaj Frost, Ulrich Kertzscher, and Gabi Wendt

Safety Analyses of NRG BR004: A Randomized, Double-blind, Phase III Trial of Taxane/Trastuzumab/Pertuzumab with Atezolizumab or Placebo in First-line HER2-Postive Metastatic Breast Cancer (MBC), CE Geyer and DB Page

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Robotic post-chemotherapy retroperitoneal lymph node dissection for testicular cancer: A multicenter collaborative study., Alireza Ghoreifi, Anirban P Mitra, George McClintock, Fady Baky, Zachary McDowell, Etienne Lavallée, Ragheed Saoud, Jie Cai, Inderbir S Gill, John Sfakianos, James R Porter, Aditya Bagrodia, Nariman Ahmadi, Scott Eggener, John F Ward, and Hooman Djaladat

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Management of recurrent transudative pleural effusions: can we REDUCE unnecessary interventions?, Christopher R Gilbert and José M Porcel

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Safety of Nivolumab Added to Chemoradiation Therapy Platforms for Intermediate and High-Risk Locoregionally Advanced Head and Neck Squamous Cell Carcinoma: Radiation Therapy Oncology Group Foundation 3504., Maura L Gillison, Robert L Ferris, Jonathan Harris, A Dimitrios Colevas, Loren K Mell, Christina Kong, Richard C Jordan, Kevin L Moore, Minh-Tam Truong, Claudia Kirsch, Arnab Chakravarti, Dukagjin M Blakaj, David A Clump, James P Ohr, John F Deeken, Michael F Gensheimer, Nabil F Saba, Jennifer A Dorth, David I Rosenthal, Rom S Leidner, Randall J Kimple, Mitchell Machtay, Walter J Curran, Pedro Torres-Saavedra, and Quynh Thu Le

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Malignant Myopericytoma of the Right Foot: A Case Report, Ryan Glendenning

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A phase 1b, multicenter, dose-escalation study of subasumstat (TAK-981) in combination with pembrolizumab in patients (pts) with advanced solid tumors., Sanjay Goel, Rachel E Sanborn, and See full list of authors in comments

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Differences in the management of thyroid nodules in children and adolescents as compared to adults., Melanie Goldfarb and Catherine Dinauer

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Survivorship, Quality of Life, and Transition to Adult Care for Pediatric and Adolescent Thyroid Cancer Survivors., Melanie Goldfarb and Aime T Franco

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COVID-19 and Cancer: Special Considerations for Patients Receiving Immunotherapy and Immunosuppressive Cancer Therapies., Jason D Goldman, Michael A Gonzalez, Maria Madeleine Rüthrich, Elad Sharon, and Marie von Lilienfeld-Toal

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Safety and tolerability of MEDI0562, an OX40 agonist monoclonal antibody, in combination with durvalumab or tremelimumab in adult patients with advanced solid tumors., Jonathan W Goldman, Sarina A Piha-Paul, Brendan Curti, Katrina S Pedersen, Todd M Bauer, Stefanie L Groenland, Richard D Carvajal, Vaishali Chhaya, Gray Kirby, Kelly McGlinchey, Scott A Hammond, Katie L Streicher, Danielle Townsley, Young Kwang Chae, Jens Voortman, Aurelien Marabelle, and John Powderly

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Safety of Tumor Treating Fields (TTFields) therapy in pediatric patients with malignant brain tumors: Post-marketing surveillance data., Stewart Goldman, Ashley Margol, Eugene I Hwang, Kazuhiro Tanaka, Bogdana Suchorska, John R Crawford, and Santosh Kesari

The Development and Dynamics of Pre-existing immunity in tumors, Michael Gough

Fluorescence tagging to monitor CD8 T cell recirculation from the tumor to the tumor-draining lymph node: the impact of focal radiation therapy on recirculation, Michael J. Gough

Tumor resident memory CD8 T cell formation and concomitant tumor immunity is CD40L dependent and CD4 independent, Michael J. Gough

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The paradox of radiation and T cells in tumors., Michael J. Gough and Marka R Crittenden

Tumor resident memory CD8 T cell formation and concomitant tumor immunity is CD40L dependent and CD4 independent., Michael J. Gough, Thomas Duhen, Marka R Crittenden, and See all authors in comments

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Primary Care Physicians and Patients Prefer Colonoscopy for Colorectal Cancer Screening., Jessica M Gowing, Beth-Ann Shanker, Tendai K Thomas, and Robert K Cleary

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Pembrolizumab plus dinaciclib in patients with hematologic malignancies: the phase 1b KEYNOTE-155 study., Gareth P Gregory, Shaji Kumar, Ding Wang, Daruka Mahadevan, Patricia Walker, Nina Wagner-Johnston, Carolina Escobar, Rajat Bannerji, Divaya Bhutani, Julie Chang, Francisco J Hernandez-Ilizaliturri, Andreas Klein, John M Pagel, Witold Rybka, Andrew J Yee, Anne Mohrbacher, Mo Huang, Mohammed Farooqui, Patricia Marinello, and Hang Quach

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Impact of neurofibromatosis type 1 in an adult community population., Timothy A Gregory, Peter Simon B Molina, Gregory D Phillips, and John W Henson

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Prospective biomarker study in newly diagnosed glioblastoma: Cyto-C clinical trial., Corinne E Griguer, Claudia R Oliva, Christopher S Coffey, Merit E Cudkowicz, Robin A Conwit, Anna L Gudjonsdottir, Dixie J Ecklund, Janel K Fedler, Tina M Neill-Hudson, Louis B Nabors, Melanie Benge, James R Hackney, Marianne Chase, Timothy P Leonard, Toral Patel, Howard Colman, Macarena de la Fuente, Rekha Chaudhary, Karen Marder, Teri Kreisl, Nimish Mohile, Milan G Chheda, Katharine McNeill, Priya Kumthekar, Aclan Dogan, Jan Drappatz, Vinay Puduvalli, Agnes Kowalska, Jerome J Graber, Elizabeth Gerstner, Stephen Clark, Michael Salacz, and James Markert

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Outcomes of Lymph Node Dissection in Nephroureterectomy in the Treatment of Upper Tract Urothelial Carcinoma: Analysis of the ROBUUST Registry., Kevin Hakimi, Umberto Carbonara, Hooman Djaladat, Reza Mehrazin, Daniel Eun, Adam Reese, Mark L Gonzalgo, Vitaly Margulis, Robert G Uzzo, James R Porter, Chandru P Sundaram, Firas Abdollah, Alexandre Mottrie, Riccardo Tellini, Matteo Ferro, Arman Walia, Ava Saidian, Shady Soliman, Julia Yuan, Alessandro Veccia, Alireza Ghoreifi, Giovanni Cacciamani, Amit S Bhattu, Xiaosong Meng, Jason M Farrow, Marcus Jamil, Andrea Minervini, Koon H Rha, Zhenjie Wu, Giuseppe Simone, Riccardo Autorino, and Ithaar H Derweesh

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Clinical Course of Two Patients with COVID-19 Respiratory Failure After Administration of the Anticancer Small Molecule, RRx-001., Terese Catherine Hammond, Raymond C Lee, Bryan Oronsky, Tony R Reid, Scott Caroen, Tiffany M Juarez, Jaya Gill, Annie Heng, and Santosh Kesari

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Intratumoral Electroporation of Plasmid Encoded IL12 and Membrane-Anchored Anti-CD3 Increases Systemic Tumor Immunity., Mia Han, Bianca Nguyen, Jack Y Lee, Erica Browning, Jun Zhang, Anandaroop Mukhopadhyay, Ravindra Gujar, Jon Salazar, Reneta Hermiz, Lauren Svenson, Annah S Rolig, William L. Redmond, Alain P Algazi, Adil I Daud, David A Canton, and Christopher G Twitty

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Long-Term Outcomes of Patients on a Phase II Prospective Trial of Oligometastatic Hormone-Sensitive Prostate Cancer Treated with Androgen Deprivation and External Beam Radiation., Claire Hao, Colton Ladbury, Yung Lyou, Saro Manoukian, Christopher Ruel, Paul Frankel, Tanya Dorff, Jeffrey Wong, Sumanta Pal, Przemyslaw Twardowski, and Savita Dandapani

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Risk factors for cervical cancer among distinct populations in low-resource countries: feasibility of cervical cancer screen-and-treat program on ukerewe island of lake victoria, Tanzania., Anjali Y Hari, Megan Bernstein, Jamie Temko, Danielle E Brabender, Aricia Shen, and Krishnansu S Tewari

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Assessment of Regional Variability in COVID-19 Outcomes Among Patients With Cancer in the United States., Jessica E Hawley, Tianyi Sun, David D Chism, Narjust Duma, Julie C Fu, Na Tosha N Gatson, Sanjay Mishra, Ryan H Nguyen, Sonya A Reid, Oscar K Serrano, Sunny R K Singh, Neeta K Venepalli, Ziad Bakouny, Babar Bashir, Mehmet A Bilen, Paolo F Caimi, Toni K Choueiri, Scott J Dawsey, Leslie A Fecher, Daniel B Flora, Christopher R Friese, Michael J Glover, Cyndi J Gonzalez, Sharad Goyal, Thorvardur R Halfdanarson, Dawn L Hershman, Hina Khan, Chris Labaki, Mark A Lewis, Rana R McKay, Ian Messing, Nathan A Pennell, Matthew Puc, Deepak Ravindranathan, Terence D Rhodes, Andrea V Rivera, John Roller, Gary K Schwartz, Sumit A Shah, Justin A Shaya, Mitrianna Streckfuss, Michael A Thompson, Elizabeth M Wulff-Burchfield, Zhuoer Xie, Peter Paul Yu, Jeremy L Warner, Dimpy P Shah, Benjamin French, Clara Hwang, COVID-19 and Cancer Consortium (CCC19), and Hagen F Kennecke (COVID-19 and Cancer Consortium (CCC19))

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EDI and open access: How JACMP is the future of ethical publishing-A tale in two parts., Samantha G Hedrick and Susan L Richardson

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Radiofrequency ablation in the management of primary hepatic and biliary tumors., Richard Hendriquez, Tara Keihanian, Jatinder Goyal, Rtika R Abraham, Rajnish Mishra, and Mohit Girotra

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Pulmonary Open, Robotic, and Thoracoscopic Lobectomy study: Outcomes and risk factors of conversion during minimally invasive lobectomy., Luis J Herrera, Lana Y Schumacher, Matthew G Hartwig, Charles T Bakhos, Rishindra M Reddy, Eric Vallieres, and Michael S Kent

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5 Development of a vaccine to intercept oral cancer, Traci Hilton, Tarsem Moudgil, Richard Bryan Bell, and See all authors in comments

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731 A first-in-human trial of an integrin beta-6 targeted antibody-drug conjugate (ADC), SGN-B6A, in patients with advanced solid tumors: interim results of a phase 1 study (SGNB6A-001), Antoine Hollebecque, Rachel E Sanborn, and See full list of authors in comments

"Cisplatin-induced DNA damage triggers MRE11a proteasomal degradation mediated by UBQLN4 in solid tumors", DSB Hoon, Y Shiloh, T Murakami, Y Kobayashi, and MA Bustos

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Meta-analysis of randomized controlled trials on primary ambulatory thromboprophylaxis in patients with nonpancreatic gastrointestinal cancers receiving chemotherapy., Thura Win Htut, Kyaw Zin Thein, Donald Quick, and Thein Hlaing Oo

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Development and Validation of a Breast Cancer Polygenic Risk Score on the Basis of Genetic Ancestry Composition., Elisha Hughes, Susanne Wagner, Dmitry Pruss, Ryan Bernhisel, Braden Probst, Victor Abkevich, Timothy Simmons, Brooke Hullinger, Thaddeus Judkins, Eric Rosenthal, Benjamin Roa, Susan M Domchek, Charis Eng, Judy Garber, Monique Gary, Jennifer Klemp, Semanti Mukherjee, Kenneth Offit, Olufunmilayo I Olopade, Joseph Vijai, Jeffrey N Weitzel, Pat Whitworth, Lamis Yehia, Ora K Gordon, Holly Pederson, Allison Kurian, Thomas P Slavin, Alexander Gutin, and Jerry S Lanchbury

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Real-world evidence of a successful biosimilar adoption program., Sophia Z Humphreys

8 Universal LCMS-based assay platform, refmAb-Q nSMOL, for monitoring monoclonal antibody therapeutics using one reference antibody, Noriko Iawmoto, Yoshinobu Koguchi, Kotoko Yokoyama, Akinobu Hamada, Atsushi Yonezawa, Brian Piening, Eric Tran, Bernard Fox, William Redmond, and Takashi Shimada

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A Blood-Based Metabolite Panel for Distinguishing Ovarian Cancer from Benign Pelvic Masses., Ehsan Irajizad, Chae Y Han, Joseph Celestino, Ranran Wu, Eunice Murage, Rachelle Spencer, Jennifer B Dennison, Jody Vykoukal, James P Long, Kim Anh Do, Charles Drescher, Karen Lu, Zhen Lu, Robert C Bast, Sam Hanash, and Johannes F Fahrmann

Proteogenomic Characterization of Head and Neck Squamous Cell Cancer Immunopeptidomes to Detect Non Canonical Protein Targets for Cancer Immunotherapy., N Iwamoto, Richard Bryan Bell, Carlo Bifulco, Walter Urba, Rom Leidner, Brian D. Piening, Bernard A Fox, and See full author list in comments

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A rapid and universal liquid chromatograph-mass spectrometry-based platform, refmAb-Q nSMOL, for monitoring monoclonal antibody therapeutics., Noriko Iwamoto, Yoshinobu Koguchi, Kotoko Yokoyama, Akinobu Hamada, Atsushi Yonezawa, Brian D Piening, Eric Tran, Bernard A Fox, William L Redmond, and Takashi Shimada

Uncovering the dark immunopeptidome of head and neck squamous cell carcinoma (HNSCC): relevance for universal cancer vaccines, immunological monitoring and TIL therapy, Noriko Iwamoto, Takashi Shimada, Tarsem Moudgil, Ryan Meng, Tanisha Christie, Alexa Dowdell, Rom Leidner, Bryan Bell, William Redmond, Eric Tran, Hong-Ming Hu, Traci Hilton, Brian Piening, Yoshinobu Koguchi, and Bernard Fox

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RECOVERY AND SURVIVAL IN COVID-19 RESPIRATORY FAILURE‚ WHEN TREATED WITH AVIPTADIL, Dushyantha Jayaweera, David J Park, and See full list of authors in comments

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Agent-based computational modeling of glioblastoma predicts that stromal density is central to oncolytic virus efficacy., Adrianne L Jenner, Munisha Smalley, David Goldman, William F Goins, Charles Cobbs, Ralph B Puchalski, E Antonio Chiocca, Sean Lawler, Paul Macklin, Aaron Goldman, and Morgan Craig

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Interim results of an ongoing phase 1/2a study of HPN328, a tri-specific, half-life extended, DLL3-targeting, T-cell engager, in patients with small cell lung cancer and other neuroendocrine cancers., Melissa Lynne Johnson, Rachel E Sanborn, and See full list of authors in comments

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Tyrosine kinase-altered spindle cell neoplasms with EGFR internal tandem duplications., Erica Kao, Navin Pinto, Angela Trobaugh-Lotrario, Gail H Deutsch, Yu Wu, Wenjing Wang, Erin R Rudzinski, and Yajuan J Liu

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PCM1-JAK2 Fusion Tyrosine Kinase Gene-Related Neoplasia: A Systematic Review of the Clinical Literature., Henry G Kaplan, Ruyun Jin, Carlo Bifulco, James M Scanlan, and David R Corwin