The Cancer Institute is a leader in cutting-edge treatments. Using a truly multidisciplinary approach, patients have access to advanced diagnostics, minimally invasive surgical interventions, and personalized genomic and immune-oncologic treatment options. Our team of cancer specialists – many of whom completed fellowships and specialty training at prestigious academic centers – offers comprehensive services for individuals with a cancer diagnosis.

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Submissions from 2023

Long-term efficacy, safety, and predictors of response to amivantamab among patients with post-platinum EGFR Ex20ins-mutated advanced NSCLC, PG Lopez, RE Sanborn, and See full list of authors in comments

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Feasibility of circulating tumor DNA (ctDNA) to guide organ preservation in patients with node-negative rectal cancer undergoing neoadjuvant chemotherapy, excision, and observation in the phase II CCTG CO.28 trial, Jonathan M. Loree, Hagen F Kennecke, and See full list of authors in comments

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ACR-ARS Practice Parameter for Radiation Oncology., Simon Lo, Samuel Chao, Eleanor Harris, Jonathan Knisely, Join Y Luh, Pranshu Mohindra, Tony S Quang, Jason Ye, William Small, and Naomi R Schechter

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Commentary: The next step forward for enhanced recovery after surgery: Postdischarge benefits., Brian Louie

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Lorigerlimab, a bispecific PD-1×CTLA-4 DART molecule in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC): A phase 1 expansion (exp) cohort., Jason J. Luke, Rachel E Sanborn, and See full list of authors in comments

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CT251 / 14 - Phase 1/2 study of HST-1011, an oral CBL-B inhibitor, alone and in combination with anti-PD1 in patients with advanced solid tumors, J Luke, Rachel E Sanborn, and See full list of authors in comments

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Neuroinflammation: A Modifiable Pathway Linking Obesity, Alzheimer's disease, and Depression., Maria Ly, Gary Z Yu, Ali Mian, Austin Cramer, Somayeh Meysami, David A Merrill, Amjad Samara, Sarah A Eisenstein, Tamara Hershey, Ganesh M Babulal, Eric J Lenze, John C Morris, Tammie L S Benzinger, and Cyrus A Raji

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Evolution in the treatment of gastroesophageal reflux disease over the last century: from a crural-centered to a lower esophageal sphincter-centered approach and back., Emily M Mackay and Brian E Louie

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A Phase Ib/II Study of Lenvatinib and Pembrolizumab in Advanced Endometrial Carcinoma (Study 111/KEYNOTE-146): Long-Term Efficacy and Safety Update., Vicky Makker, Carol Aghajanian, Allen L Cohn, Margarita Romeo, Raquel Bratos, Marcia S Brose, Mark Messing, Lea Dutta, Corina E Dutcus, Jie Huang, Emmett V Schmidt, Robert Orlowski, and Matthew H Taylor

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Persistence of patient-detected breast cancer over time: 1990-2019., Judith A Malmgren, Mary K Atwood, and Henry G Kaplan

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COVID-19 related change in breast cancer diagnosis, stage, treatment, and case volume: 2019-2021., Judith A Malmgren, Boya Guo, Mary K Atwood, Paula Hallam, Laura A Roberts, and Henry G Kaplan

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Plasma phosphocreatine (PC) as a predictive biomarker for immune checkpoint inhibition in patients with refractory metastatic colorectal cancer (mCRC): Analysis of the CCTG CO.26 trial., Lucy Xiaolu Ma, Hagen F Kennecke, and See full list of authors in comments

Plasma arginine as a candidate predictive biomarker for response to immune checkpoint inhibition (ICI) in metastatic colorectal cancer (mCRC): Analysis of the CCTG CO.26 trial, LX Ma, H Kennecke, and See all authors in comments

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Structural surfaceomics reveals an AML-specific conformation of integrin β, Kamal Mandal, Gianina Wicaksono, Clinton Yu, Jarrett J Adams, Michael R Hoopmann, William C Temple, Adila Izgutdina, Bonell Patiño Escobar, Maryna Gorelik, Christian H Ihling, Matthew A Nix, Akul Naik, William H Xie, Juwita Hübner, Lisa A Rollins, Sandy M Reid, Emilio Ramos, Corynn Kasap, Veronica Steri, Juan Antonio Camara Serrano, Fernando Salangsang, Paul Phojanakong, Melanie McMillan, Victor Gavallos, Andrew D Leavitt, Aaron C Logan, Cliona M Rooney, Justin Eyquem, Andrea Sinz, Benjamin J Huang, Elliot Stieglitz, Catherine C Smith, Robert L Moritz, Sachdev S Sidhu, Lan Huang, and Arun P Wiita

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Precision nephrology identified tumor necrosis factor activation variability in minimal change disease and focal segmental glomerulosclerosis., Laura H Mariani, Sean Eddy, Fadhl M AlAkwaa, Phillip J McCown, Jennifer L Harder, Viji Nair, Felix Eichinger, Sebastian Martini, Adebowale D Ademola, Vincent Boima, Heather N Reich, Jamal El Saghir, Bradley Godfrey, Wenjun Ju, Emily C Tanner, Virginia Vega-Warner, Noel L Wys, Sharon G Adler, Gerald B Appel, Ambarish Athavale, Meredith A Atkinson, Serena M Bagnasco, Laura Barisoni, Elizabeth Brown, Daniel C Cattran, Gaia M Coppock, Katherine M Dell, Vimal K Derebail, Fernando C Fervenza, Alessia Fornoni, Crystal A Gadegbeku, Keisha L Gibson, Laurence A Greenbaum, Sangeeta R Hingorani, Michelle A Hladunewich, Jeffrey B Hodgin, Marie C Hogan, Lawrence B Holzman, J Ashley Jefferson, Frederick J Kaskel, Jeffrey B Kopp, Richard A Lafayette, Kevin V Lemley, John C Lieske, Jen-Jar Lin, Rajarasee Menon, Kevin E Meyers, Patrick H Nachman, Cynthia C Nast, Michelle M O'Shaughnessy, Edgar A Otto, Kimberly J Reidy, Kamalanathan K Sambandam, John R Sedor, Christine B Sethna, Pamela Singer, Tarak Srivastava, Cheryl L Tran, Katherine Tuttle, Suzanne M Vento, Chia-Shi Wang, Akinlolu O Ojo, Dwomoa Adu, Debbie S Gipson, Howard Trachtman, and Matthias Kretzler

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Hyper-Dependence on NHEJ Enables Synergy Between DNA-PK Inhibitors and Low-Dose Doxorubicin in Leiomyosarcoma., Adrián Mariño-Enríquez, Jan Philipp Novotny, Doga C Gulhan, Isabella Klooster, Antuan V Tran, Macy Kasbo, Meijun Z Lundberg, Wen-Bin Ou, Derrick L Tao, Daniel F Pilco-Janeta, Victor Y Mao, Frank T Zenke, Brittaney A Leeper, Prafulla C Gokhale, Glenn S Cowley, Laurence H Baker, Karla V Ballman, David E Root, Joachim Albers, Peter J Park, Suzanne George, and Jonathan A Fletcher

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Pirtobrutinib after a Covalent BTK Inhibitor in Chronic Lymphocytic Leukemia., Anthony R Mato, Jennifer A Woyach, Jennifer R Brown, Paolo Ghia, Krish Patel, Toby A Eyre, Talha Munir, Ewa Lech-Maranda, Nicole Lamanna, Constantine S Tam, Nirav N Shah, Catherine C Coombs, Chaitra S Ujjani, Bita Fakhri, Chan Y Cheah, Manish R Patel, Alvaro J Alencar, Jonathon B Cohen, James N Gerson, Ian W Flinn, Shuo Ma, Deepa Jagadeesh, Joanna M Rhodes, Francisco Hernandez-Ilizaliturri, Pier L Zinzani, John F Seymour, Minna Balbas, Binoj Nair, Paolo Abada, Chunxiao Wang, Amy S Ruppert, Denise Wang, Donald E Tsai, William G Wierda, and Wojciech Jurczak

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Operational Ontology for Oncology (O3) - A Professional Society Based, Multi-Stakeholder, Consensus Driven Informatics Standard Supporting Clinical and Research use of "Real -World" Data from Patients Treated for Cancer: Operational Ontology for Radiation Oncology., C S Mayo, M U Feng, K K Brock, R Kudner, P Balter, J C Buchsbaum, A Caissie, E Covington, E C Daugherty, A L Dekker, C D Fuller, A L Hallstrom, D S Hong, J C Hong, S C Kamran, E Katsoulakis, J Kildea, A V Krauze, J J Kruse, T McNutt, M Mierzwa, A Moreno, J R Palta, R Popple, T G Purdie, Susan L Richardson, G C Sharp, S Shiraishi, L Tarbox, A M Venkatesan, A Witztum, K E Woods, J Yao, K Farahani, S Aneja, P E Gabriel, L Hadjiiski, D Ruan, J H Siewerdsen, S Bratt, M Casagni, S Chen, J Christodouleas, A DiDonato, J Hayman, R Kapoor, S Kravitz, S Sebastian, M Von Siebenthal, and Y Xiao

Neoadjuvant HER2-targeted Therapy +/- Immunotherapy with Pembrolizumab (neoHIP): An Open Label Randomized Phase II Trial, H McArthur, David B. Page, and See all authors in comments

A Single Arm Phase 2 Study of Peri-Operative Immune Checkpoint Inhibition and Cryoablation in Women With Hormone Receptor-Negative, HER2-Negative Early Stage/Resectable Breast Cancer, H McArthur, David Page, and See full list of authors in comments

Neoadjuvant HER2-targeted Therapy +/- Immunotherapy with Pembrolizumab (neoHIP): An Open Label Randomized Phase II Trial, H McArthur, David Page, and See full list of authors in comments

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Missed Opportunities: the Timing and Frequency of Screening Colonoscopy in Patients That Develop Esophageal Adenocarcinoma., Sarah C McKay, Melissa L DeSouza, Christy M Dunst, Kevin M Reavis, Daniel Davila Bradley, and Steven R DeMeester

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Missed Opportunities: the Timing and Frequency of Screening Colonoscopy in Patients That Develop Esophageal Adenocarcinoma., Sarah C McKay, Melissa L DeSouza, Christy M Dunst, Kevin M Reavis, Daniel Davila Bradley, and Steven R DeMeester

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Tumor differentiation impacts response to neoadjuvant therapy and survival in patients with esophageal adenocarcinoma., Sarah C McKay, Brian Louie, Daniela Molena, Weston G Andrews, Thomas Boerner, Wayne L Hofstetter, Jonathan Yeung, Gail E Darling, Ahmed Sharata, Christian G Peyre, Colin Dunn, John C Lipham, Horia Marginean, and Steven R DeMeester

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Safety of Extending Implanted Vascular Access Device Maintenance Flush Frequency., Monica McManus, Mary Jo Sarver, Elizabeth Ser, and Kelle Rene Gross

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Myeloid MyD88 restricts CD8+ T cell response to radiation therapy in pancreatic cancer, Terry R Medler, Tiffany Blair, Alejandro F Alice, Alexa K Dowdell, Brian D. Piening, Marka R Crittenden, and Michael J. Gough

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Myeloid MyD88 restricts CD8, Terry R Medler, Tiffany C Blair, Alejandro F Alice, Alexa K Dowdell, Brian D Piening, Marka R Crittenden, and Michael J Gough

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Tumor resident memory CD8 T cells and concomitant tumor immunity develop independently of CD4 help., Terry R Medler, Gwen Kramer, Shelly Bambina, Andrew J Gunderson, Alejandro Alice, Tiffany Blair, Lauren Zebertavage, Thomas Duhen, Rebekka Duhen, Kristina Young, Marka R Crittenden, and Michael J Gough

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Muscle mass cross-sectional area is associated with survival outcomes in malignant pleural disease related to lung cancer., Austin M Meggyesy, Candice L. Wilshire, Shu-Ching Chang, Jed A Gorden, and Christopher R Gilbert

Characterizing cancer’s dark matter, short-lived proteins, and defective ribosomal products, presented by cancer and contained in the DPV-001 cancer vaccine, R Meng, Will Redmond, Carlo Bifulco, Rachel Sanborn, RB Bell, Walter Urba, Rom Leidner, Brian Piening, Bernard Fox, and See full list of authors in comments

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Cobimetinib Plus Vemurafenib in Patients With Solid Tumors With, Funda Meric-Bernstam, Michael Rothe, Pam K Mangat, Elizabeth Garrett-Mayer, Rodolfo Gutierrez, Eugene R Ahn, Timothy L Cannon, Steven Powell, John C Krauss, Christopher M Reynolds, Margaret von Mehren, Deepti Behl, Carmen J Calfa, Herbert L Duvivier, Henry G Kaplan, Michael B Livingston, Manish R Sharma, Walter Urba, Gina N Grantham, Dominique C Hinshaw, Abigail Gregory, Susan Halabi, and Richard L Schilsky

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Novel TCF4:TCF12 heterodimer inhibits glioblastoma growth., Svetlana A Mikheeva, Cory C Funk, Philip J Horner, Robert C Rostomily, and Andrei M Mikheev

Abstract CT226: Crizotinib (C) in patients (pts) with solid tumors with MET amplification (amp) or mutation (mut): Results from the Targeted Agent and Profiling Utilization Registry (TAPUR) Study, Kathryn F. Mileham, Rom Leidner, and See full list of authors in comments

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Breast Cancer Screening, Diagnosis, and Surgery during the Pre- and Peri-pandemic: Experience of Patients in a Statewide Health Information Exchange., Zheng Z Milgrom, Daniel P Milgrom, Yan Han, Siu L Hui, David A Haggstrom, Carla S Fisher, and Eneida A Mendonca

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ASO Author Reflections: Patient Interest and Outcomes with Simultaneous Symmetry Procedures in Oncoplastic Breast-Conserving Surgery., Janelle-Cheri Millen and Janie Grumley

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Simultaneous Symmetry Procedure in Patients Undergoing Oncoplastic Breast-Conserving Surgery: An Evaluation of Patient Desire and Revision Rates., Janelle-Cheri Millen, Katherine M Jackson, Stacey Stern, Javier I Orozco, Crystal E Fancher, and Janie Grumley

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ASO Visual Abstract: Simultaneous Symmetry Procedure in Patients Undergoing Oncoplastic Breast-Conserving Surgery: An Evaluation of Patient Desire and Revision Rates., Janelle-Cheri Millen, Katherine Jackson, Stacey L Stern, Javier I J Orozco, Crystal E Fancher, and Janie Grumley

Simultaneous identification of KRAS mutation-carrying multiple neoepitopes by differential ion mobility-assisted targeted-mass spectrometry, Y Minegishi, Eric Tran, Will Redmond, Brian Piening, Bernard Fox, and See all authors in comments

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Multicenter International Study of the Consensus Immunoscore for the Prediction of Relapse and Survival in Early-Stage Colon Cancer., Bernhard Mlecnik, Alessandro Lugli, Gabriela Bindea, Florence Marliot, Carlo Bifulco, Jiun-Kae Jack Lee, Inti Zlobec, Tilman T Rau, Martin D Berger, Iris D Nagtegaal, Elisa Vink-Börger, Arndt Hartmann, Carol I Geppert, Julie Kolwelter, Susanne Merkel, Robert Grützmann, Marc Van den Eynde, Anne Jouret-Mourin, Alex Kartheuser, Daniel Léonard, Christophe Remue, Julia Wang, Prashant Bavi, Michael H A Roehrl, Pamela S Ohashi, Linh T Nguyen, SeongJun Han, Heather L MacGregor, Sara Hafezi-Bakhtiari, Bradly G Wouters, Giuseppe V Masucci, Emilia K Andersson, Eva Zavadova, Michal Vocka, Jan Spacek, Lubos Petruzelka, Bohuslav Konopasek, Pavel Dundr, Helena Skalova, Kristyna Nemejcova, Gerardo Botti, Fabiana Tatangelo, Paolo Delrio, Gennaro Ciliberto, Michele Maio, Luigi Laghi, Fabio Grizzi, Tessa Fredriksen, Bénédicte Buttard, Lucie Lafontaine, Pauline Maby, Amine Majdi, Assia Hijazi, Carine El Sissy, Amos Kirilovsky, Anne Berger, Christine Lagorce, Christopher Paustian, Carmen Ballesteros-Merino, Jeroen Dijkstra, Carlijn van de Water, Shannon van Lent-van Vliet, Nikki Knijn, Ana-Maria Mușină, Dragos-Viorel Scripcariu, Boryana Popivanova, Mingli Xu, Tomonobu Fujita, Shoichi Hazama, Nobuaki Suzuki, Hiroaki Nagano, Kiyotaka Okuno, Toshihiko Torigoe, Noriyuki Sato, Tomohisa Furuhata, Ichiro Takemasa, Prabhu Patel, Hemangini H Vora, Birva Shah, Jayendrakumar B Patel, Kruti N Rajvik, Shashank J Pandya, Shilin N Shukla, Yili Wang, Guanjun Zhang, Yutaka Kawakami, Francesco M Marincola, Paolo A Ascierto, Bernard A Fox, Franck Pagès, and Jérôme Galon

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Health-related quality of life with pembrolizumab or placebo plus chemotherapy with or without bevacizumab for persistent, recurrent, or metastatic cervical cancer (KEYNOTE-826): a randomised, double-blind, placebo-controlled, phase 3 trial., Bradley J Monk, Krishnansu S Tewari, Coraline Dubot, M Valeria Caceres, Kosei Hasegawa, Ronnie Shapira-Frommer, Pamela Salman, Eduardo Yañez, Mahmut Gümüş, Mivael Olivera Hurtado de Mendoza, Vanessa Samouëlian, Vincent Castonguay, Alexander Arkhipov, Cumhur Tekin, Kan Li, Allison Martin Nguyen, Matthew J Monberg, Nicoletta Colombo, and Domenica Lorusso

Peripheral and tissue persistence of agenT-797, an allogeneic iNKT cell-based cell therapy for the treatment of cancer, J Moon, Rachel Sanborn, Dave Hoon, and See full list of authors in comments

A phase 1/1b study of the tumor-activated IL-2 prodrug WTX-124 alone or in combination with pembrolizumab in patients with immunotherapy-sensitive locally advanced or metastatic solid tumors, JC Moser, Brendan Curti, and See full list of authors in comments

PD-1 expression on tumor-infiltrating T-lymphocytes as determinant of the head and neck cancer tumor immune microenvironment rather than anatomical site, T Muijlwijk, Bernard Fox, and See full list of authors in comments

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Breast Conservation Surgery and Mastectomy have Similar Locoregional Recurrence Following Neoadjuvant Chemotherapy: Results from 1,462 Patients on the Prospective, Randomized I-SPY2 Trial., Rita A Mukhtar, Harrison Chau, Hannah Woriax, Mara Piltin, Gretchen Ahrendt, Julia Tchou, Hongmei Yu, Qian Ding, Catherine Lu Dugan, Jori Sheade, Angelena Crown, Michael Carr, Jasmine Wong, Jennifer Son, Rachel Yang, Theresa Chan, Alicia Terando, Michael Alvarado, Cheryl Ewing, Jennifer Tonneson, Nina Tamirisa, Rebekah Gould, Puneet Singh, Constantine Godellas, Kelsey Larson, Akiko Chiba, Roshni Rao, Candice Sauder, Lauren Postlewait, Marie Catherine Lee, William Fraser Symmans, Laura J Esserman, Judy C Boughey, and ISPY-2 Locoregional Working Group

Localized Contrastive and Attention Based Multiple Instance Learning for Automatic Staging of Histopathology Images., N Naik, Carlo Bifulco, Brian Piening, and See full list of authors in comments

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Mycotic Aneurysm a Rare Complication from Infection Masquerading as Lung Cancer, Rithvik Nallapareddy, MD and Mary Anne Nidiry, MD

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Integrated Hospital- and Home-Based Palliative Care for Cancer Patients in Vietnam: People-Centered Outcomes., Viet Nguyen, Quach Thanh Khanh, Mevhibe Hocaoglu, Hoang Thi Mong Huyen, Dang Huy Quoc Thinh, and Eric L Krakauer

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Building the foundation for a community-generated national research blueprint for inherited bleeding disorders: research priorities for ultra-rare inherited bleeding disorders., Diane Nugent, Suchitra S Acharya, Kimberly J Baumann, Camille Bedrosian, Rebecca Bialas, Kai Brown, Deya Corzo, Amar Haidar, Catherine P M Hayward, Peter Marks, Marzia Menegatti, Margaret E Miller, Kate Nammacher, Roberta Palla, Skye Peltier, Rajiv K Pruthi, Michael Recht, Benny Sørensen, Michael Tarantino, Alisa S Wolberg, and Amy D Shapiro

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Building the foundation for a community-generated national research blueprint for inherited bleeding disorders: research priorities for ultra-rare inherited bleeding disorders., Diane Nugent, Suchitra S Acharya, Kimberly J Baumann, Camille Bedrosian, Rebecca Bialas, Kai Brown, Deya Corzo, Amar Haidar, Catherine P M Hayward, Peter Marks, Marzia Menegatti, Margaret E Miller, Kate Nammacher, Roberta Palla, Skye Peltier, Rajiv K Pruthi, Michael Recht, Benny Sørensen, Michael Tarantino, Alisa S Wolberg, and Amy D Shapiro

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A Plain Language Summary of Results from the GARNET Study of Dostarlimab in Patients with Endometrial Cancer., Ana Oaknin, Lucy Gilbert, Anna V Tinker, Jubilee Brown, Cara Mathews, Joshua Press, Renaud Sabatier, David M O'Malley, Vanessa Samouelian, Valentina Boni, Linda Duska, Sharad Ghamande, Prafull Ghatage, Rebecca Kristeleit, Charles Leath, Yuping Dong, Jennifer Veneris, and Bhavana Pothuri

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Reconstructing the Mandible: Jaw-In-A-Day: Where We Were, Where We Are, and the Future., David Omole, Baber Khatib, Ashish A Patel, Allen Cheng, Andrew Salama, Lawrence E Brecht, and David L Hirsch

Molecular features associated with long survival on tebentafusp in previously untreated metastatic uveal melanoma in a phase 3 trial, M Orloff, Brendan Curti, and See full list of authors in comments

A phase II study of nivolumab plus ipilimumab and androgen receptor antagonist bicalutamide to stimulate thymic T cell generation in HER2-negative metastatic breast cancer. Page D. SABCS Annual Meeting; 2023 December 7; San Antonio, TX., David Page

Association of pathologic complete response with the 27-gene IO score and week 3 IOpath response following neoadjuvant pembrolizumab +/- intralymphatic cytokines in the neoIRX trial. Page D. SABCS Annual Meeting; 2023 December 6; San Antonio, TX., David Page

Novel Directions of ADCs in Breast Cancer. Binaytara Foundation Highlights from SABCS 2022; 2023 January 20; Seattle, WA., David B Page

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A phase Ib trial of pembrolizumab plus paclitaxel or flat-dose capecitabine in 1st/2nd line metastatic triple-negative breast cancer., David B Page, Joanna Pucilowska, Brie Chun, Isaac Kim, Katherine Sanchez, Nicole Moxon, Staci Mellinger, Yaping Wu, Yoshinobu Koguchi, Valerie Conrad, William L Redmond, Maritza Martel, Zhaoyu Sun, Mary B Campbell, Alison Conlin, Anupama Acheson, Reva Basho, Philomena McAndrew, Mary El-Masry, Dorothy Park, Laura Bennetts, Robert S Seitz, Tyler J Nielsen, Kimberly McGregor, Venkatesh Rajamanickam, Brady Bernard, Walter J Urba, and Heather L McArthur

A phase II study of nivolumab plus ipilimumab and androgen receptor antagonist bicalutamide to stimulate thymic T cell generation in HER2-negative metastatic breast cancer, David Page, Allison Conlin, Sasha Stanton, Walter Urba, Will Redmond, and See full list of authors in comments

Association of pathologic complete response with the 27-gene IO score and week 3 IOpath response following neoadjuvant pembrolizumab +/- intralymphatic cytokines in the neoIRX trial, David Page, Will Redmond, Allison Conlin, S Stanton, and See full list of authors in comments

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Multi-institutional validation of a radiomics-based artificial intelligence method for predicting response to PD-1/PD-L1 immune checkpoint inhibitor (ICI) therapy in stage IV NSCLC, RB Parikh, Brendan Curti, and See full list of authors in comments

Phase 1/2 study of the bispecific 4–1BB and PD-L1 antibody INBRX-105 alone and in combination with pembrolizumab in select solid tumors, JC Park, Rachel Sanborn, and See full list of authors in comments

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Management of infusion-related reactions (IRRs) in patients receiving amivantamab in the CHRYSALIS study., Keunchil Park, Joshua K Sabari, Eric B Haura, Catherine A Shu, Alexander Spira, Ravi Salgia, Karen L Reckamp, Rachel E Sanborn, Ramaswamy Govindan, Joshua M Bauml, Joshua C Curtin, John Xie, Amy Roshak, Patricia Lorenzini, Dawn Millington, Meena Thayu, Roland E Knoblauch, and Byoung Chul Cho

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268 - Outpatient CAR T Cell Therapy Is Safe and Feasible in Patients with Lymphoma Treated in Non-University Medical Centers: A Multicenter, Retrospective Analysis, Krish Patel, Megumi Bailey, Neil Bailey, Suzanne Fanning, Kayla Gulley, Jens Frisvold, Sonia Glennie, Vanessa Dunleavy, Sandra Benitez-Kruidenier, Julia Parker, Shannon Williams, Suzan Sullivan, Carol Dean, Heidi Hohmann, Chiachun Lu, Catherine Tierney, Grace Mun, Daniel N Egan, and James Essell

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CT132 / 20 - Trial in progress: A phase 1/2 study of ASP1570, a novel inhibitor of DGKζ, in participants with locally advanced or metastatic solid tumors who have progressed on, or are ineligible for, all available standard therapies, Manish R. Patel, David J Park, and See full list of authors in comments

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Screening for occult cancer after unprovoked venous thromboembolism: Assessing the current literature and future directions., Sarah S Patel, Derrick Tao, Hannah S McMurry, and Joseph J Shatzel

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Incidence, demographics, and survival of malignant hemangioendothelioma in the United States., Kelly G Paulson, Vinod Ravi, Brian P Rubin, Min Park, Elizabeth T Loggers, Lee D Cranmer, and Michael J Wagner

Multi-parametric assessment of the immune response to a trio immunotherapy in patients with recurrent or metastatic head and neck squamous cell carcinoma, C Paustian, Matthew Taylor, Will Redmond, B Bernard, RB Bell, Carlo Bifulco, Brian Piening, Walter Urba, Bernard Fox, Rom Leidner, and See full list of authors in comments

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Using Aromatherapy to Improve Nighttime Comfort in Hospitalized Patients With Cancer: A Pilot Study., Leah Phillips, Marwa Kilani, Sherri Mendelson, and Ross J Bindler

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Does Aromatherapy Improve Nighttime Comfort for Hospitalized Oncology Patients: A Pilot Study, Leah Phillips, Sherri Mendelson, Marwa Kilani, and Ross Bindler

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Correction to: Clinical characteristics associated with falls in patients with non-metastatic castration-resistant prostate cancer treated with apalutamide., YaoYao Pollock, Matthew R Smith, Fred Saad, Simon Chowdhury, Stéphane Oudard, Boris Hadaschik, David Olmos, Ji Youl Lee, Hiroji Uemura, Amitabha Bhaumik, Anil Londhe, Brendan Rooney, Sabine D Brookman-May, Peter De Porre, Suneel D Mundle, and Eric J Small

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Abstract 6764: Multi-parametric comparison of scRNA-seq with CITE-seq and ultrahigh-plex spatial phenotyping of proteins in FFPE head and neck tumor biopsies: An opportunity to generate uniquely comprehensive multi-omic single cell datasets to investigate the tumor microenvironment, Aditya Pratapa, Brady Bernard, Brian D. Piening, Rom Leidner, Bernard A Fox, and See all authors in comments

The role of dendritic cells in radiation-induced immune responses., A Preet Kaur, A Alice, MR Crittenden, and MJ Gough

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Toward structuring real-world data: Deep learning for extracting oncology information from clinical text with patient-level supervision., Sam Preston, Mu Wei, Rajesh Rao, Robert Tinn, Naoto Usuyama, Michael Lucas, Yu Gu, Roshanthi Weerasinghe, Soohee Lee, Brian D. Piening, Paul Tittel, Naveen Valluri, Tristan Naumann, Carlo Bifulco, and Hoifung Poon

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Neoantigen-targeted CD8+ T cell responses with PD-1 blockade therapy, Cristina Puig-Saus, Barbara Sennino, Songming Peng, Clifford L Wang, Zheng Pan, Benjamin Yuen, Bhamini Purandare, Duo An, Boi B Quach, Diana Nguyen, Huiming Xia, Sameeha Jilani, Kevin Shao, Claire McHugh, John Greer, Phillip Peabody, Saparya Nayak, Jonathan Hoover, Sara Said, Kyle Jacoby, Olivier Dalmas, Susan P Foy, Andrew Conroy, Michael C Yi, Christine Shieh, William Lu, Katharine Heeringa, Yan Ma, Shahab Chizari, Melissa J Pilling, Marc Ting, Ramya Tunuguntla, Salemiz Sandoval, Robert Moot, Theresa Hunter, Sidi Zhao, Justin D Saco, Ivan Perez-Garcilazo, Egmidio Medina, Agustin Vega-Crespo, Ignacio Baselga-Carretero, Gabriel Abril-Rodriguez, Grace Cherry, Deborah J Wong, Jasreet Hundal, Bartosz Chmielowski, Daniel E Speiser, Michael T Bethune, Xiaoyan R Bao, Alena Gros, Obi L Griffith, Malachi Griffith, James R Heath, Alex Franzusoff, Stefanie J Mandl, and Antoni Ribas

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A Network Landscape of HPVOPC Reveals Methylation Alterations as Significant Drivers of Gene Expression via an Immune-Mediated GPCR Signal., Jesse R Qualliotine, Takuya Nakagawa, Sara Brin Rosenthal, Sayed Sadat, Carmen Ballesteros-Merino, Guorong Xu, Adam Mark, Art Nasamran, J Silvio Gutkind, Kathleen M Fisch, Theresa Guo, Bernard A Fox, Zubair Khan, Alfredo A Molinolo, and Joseph A Califano

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Visceral and Subcutaneous Abdominal Fat Predict Brain Volume Loss at Midlife in 10,001 Individuals., Cyrus A Raji, Somayeh Meysami, Sam Hashemi, Saurabh Garg, Nasrin Akbari, Ahmed Gouda, Yosef Gavriel Chodakiewitz, Thanh Duc Nguyen, Kellyann Niotis, David A Merrill, and Rajpaul Attariwala

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Cancer stem cell assay-guided chemotherapy improves survival of patients with recurrent glioblastoma in a randomized trial., Tulika Ranjan, Soma Sengupta, Michael J Glantz, Richard M Green, Alexander Yu, Dawit Aregawi, Rekha Chaudhary, Ricky Chen, Mario Zuccarello, Christine Lu-Emerson, Hugh D Moulding, Neil Belman, Jon Glass, Aaron Mammoser, Mark Anderson, Jagan Valluri, Nicholas Marko, Jason Schroeder, Steven Jubelirer, Frances Chow, Pier Paolo Claudio, Anthony M Alberico, Seth T Lirette, Krista L Denning, and Candace M Howard

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Genomic characterization of IDH-mutant astrocytoma progression to grade 4 in the treatment setting., Kirsi J Rautajoki, Serafiina Jaatinen, Anja Hartewig, Aliisa M Tiihonen, Matti Annala, Iida Salonen, Masi Valkonen, Vili Simola, Elisa M Vuorinen, Anni Kivinen, Minna J Rauhala, Riikka Nurminen, Kendra K Maass, Sirpa-Liisa Lahtela, Arja Jukkola, Olli Yli-Harja, Pauli Helén, Kristian W Pajtler, Pekka Ruusuvuori, Joonas Haapasalo, Wei Zhang, Hannu Haapasalo, and Matti Nykter

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Challenges and opportunities in the development of combination immunotherapy with OX40 agonists., William L Redmond

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Enhancement of anti-tumor efficacy of immune checkpoint blockade by alpha-TEA., William L. Redmond, Melissa Kasiewicz, and Emmanuel T Akporiaye

Multimodal single-cell analysis of human TILs across multiple tumor types reveals heterogeneity and potential opportunities for personalized immunotherapy, Will Redmond and See all authors in comments

Advances in Cancer Immunotherapy, WL Redmond

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AAPM medical physics practice guideline 13.a: HDR brachytherapy, part A., Susan L Richardson, Ivan M Buzurovic, Gil'ad N Cohen, Wesley S Culberson, Claire Dempsey, Bruce Libby, Christopher S Melhus, Robin A Miller, Daniel J Scanderbeg, and Samantha J Simiele

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Journal impact factors and the future of open access publishing., Susan L Richardson and Samantha G Hedrick

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Spontaneous Rupture of a Previously Asymptomatic Giant Angiomyolipoma, Reed Ritterbusch

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Multi-institutional Assessment of Pathologist Scoring HER2 Immunohistochemistry., Charles J Robbins, Aileen I Fernandez, Gang Han, Serena Wong, Malini Harigopal, Mirna Podoll, Kamaljeet Singh, Amy Ly, M Gabriela Kuba, Hannah Wen, Mary Ann Sanders, Jane Brock, Shi Wei, Oluwole Fadare, Krisztina Hanley, Julie Jorns, Olivia L Snir, Esther Yoon, Kim Rabe, T Rinda Soong, Emily S Reisenbichler, and David L Rimm

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Baseline Features and Reasons for Nonparticipation in the Colonoscopy Versus Fecal Immunochemical Test in Reducing Mortality From Colorectal Cancer (CONFIRM) Study, a Colorectal Cancer Screening Trial., Douglas J Robertson, Jason A Dominitz, Alexander Beed, Kathy D Boardman, Barbara J Del Curto, Peter D Guarino, Thomas F Imperiale, Andrew LaCasse, Meaghan F Larson, Samir Gupta, David Lieberman, Beata Planeta, Aasma Shaukat, Shanaz Sultan, Stacy B Menees, Sameer D Saini, Philip Schoenfeld, Stephan Goebel, Erik C von Rosenvinge, Gyorgy Baffy, Ildiko Halasz, Marcos C Pedrosa, Lyn Sue Kahng, Riaz Cassim, Katarina B Greer, Margaret F Kinnard, Divya B Bhatt, Kerry B Dunbar, William V Harford, John A Mengshol, Jed E Olson, Swati G Patel, Fadi Antaki, Deborah A Fisher, Brian A Sullivan, Christopher Lenza, Devang N Prajapati, Helen Wong, Rebecca Beyth, John G Lieb, Joseph Manlolo, Fernando V Ona, Rhonda A Cole, Natalia Khalaf, Charles J Kahi, Divyanshoo R Kohli, Tarun Rai, Prateek Sharma, Jiannis Anastasiou, Curt Hagedorn, Ronald S Fernando, Christian S Jackson, M Mazen Jamal, Robert H Lee, Farrukh Merchant, Folasade P May, Joseph R Pisegna, Endashaw Omer, Dipendra Parajuli, Adnan Said, Toan D Nguyen, Claudio Ruben Tombazzi, Paul A Feldman, Leslie Jacob, Rachel N Koppelman, Kyle P Lehenbauer, Deepak S Desai, Mohammad F Madhoun, William M Tierney, Minh Q Ho, Heather J Hockman, Christopher Lopez, Emily Carter Paulson, Martin Tobi, Hugo L Pinillos, Michele Young, Nancy C Ho, Ranjan Mascarenhas, Kirrichai Promrat, Pritesh R Mutha, William M Pandak, Tilak Shah, Mitchell Schubert, Frank S Pancotto, Andrew J Gawron, Amelia E Underwood, Samuel B Ho, Priscilla Magno-Pagatzaurtundua, Doris H Toro, Charles H Beymer, Andrew M Kaz, Jill Elwing, Jeffrey A Gill, Susan F Goldsmith, Michael D Yao, Petr Protiva, Heiko Pohl, and Tassos Kyriakides

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Bilateral Renal Auto-Transplantation for Retroperitoneal Sarcomas: Is It Underutilized?, Tyler P Robinson, Daniel P Milgrom, Santosh Nagaraju, William C Goggins, Kannan P Samy, and Leonidas G Koniaris

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Abstract CT133: Trial in progress: a multicenter phase 1/1b dose escalation study of WTX-124 as a monotherapy and in combination with pembrolizumab in patients with selected advanced or metastatic solid tumors, I Rodriquez-Rivera, Brendan Curti, and See full list of authors in comments

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Nivolumab Plus Ipilimumab in Patients With Solid Tumors With, Nitin Rohatgi, Michael Rothe, Pam K Mangat, Elizabeth Garrett-Mayer, Funda Meric-Bernstam, Evan Pisick, Olatunji B Alese, Christopher M Reynolds, Ramya Thota, Gina Vaccaro, Margaret von Mehren, Rebecca C Arend, Vi K Chiu, Herbert L Duvivier, Philip J Gold, Keely Hack, Alissa S Marr, Arthur Winer, Gina N Grantham, Dominique C Hinshaw, Abigail Gregory, Susan Halabi, and Richard L Schilsky

Intratumoral bacteria influence immunotherapy efficacy, AS Rolig, GH McGee, and Will Redmond

Antibiotic-induced yeast overgrowth impairs efficacy of aPD-1 immunotherapy, AS Rolig, GH McGee, and WL Redmond

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Characterization of murine lymphocyte activation and exhaustion markers by a 14-color flow cytometry panel., Daniel Rose, Annah S Rolig, and William L. Redmond

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Mitomycin Gel (UGN-101) as a Kidney-sparing Treatment for Upper Tract Urothelial Carcinoma in Patients with Imperative Indications and High-grade Disease., Kyle M Rose, Katie S Murray, Craig Labbate, Solomon Woldu, Jennifer Linehan, Joseph Jacob, Hristos Kaimakliotis, Rian Dickstein, Adam Feldman, Surena F Matin, Yair Lotan, Mitchell R Humphreys, and Wade J Sexton

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Polyclonal lymphoid expansion drives paraneoplastic autoimmunity in neuroblastoma., Miriam I Rosenberg, Erez Greenstein, Martin Buchkovich, Ayelet Peres, Eric Santoni-Rugiu, Lei Yang, Martin Mikl, Zalman Vaksman, David L Gibbs, Dan Reshef, Amy Salovin, Meredith S Irwin, Arlene Naranjo, Igor Ulitsky, Pedro A de Alarcon, Katherine K Matthay, Victor Weigman, Gur Yaari, Jessica A Panzer, Nir Friedman, and John M Maris

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The rationale, design and baseline data of FLOW, a kidney outcomes trial with once-weekly semaglutide in people with type 2 diabetes and chronic kidney disease., Peter Rossing, Florian M M Baeres, George Bakris, Heidrun Bosch-Traberg, Mette Gislum, Stephen C L Gough, Thomas Idorn, Jack Lawson, Kenneth W Mahaffey, Johannes F E Mann, Henriette Mersebach, Vlado Perkovic, Katherine Tuttle, and Richard Pratley

Safety and efficacy of D-1553 in KRAS G12C-mutated colorectal cancer: Results from a phase I/II study, D-Y Ruan, Rachel Sanborn, and See all authors in comments

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Phase 1, open-label, dose-escalation study on the safety, pharmacokinetics, and preliminary efficacy of intravenous Coxsackievirus A21 (V937), with or without pembrolizumab, in patients with advanced solid tumors., Charles M Rudin, Hardev S Pandha, Matthew Zibelman, Wallace L Akerley, Kevin J Harrington, Daphne Day, Andrew G Hill, Steven J O'Day, Timothy D Clay, Gavin M Wright, Ross R Jennens, David E Gerber, Jonathan E Rosenberg, Christy Ralph, David C Campbell, Brendan Curti, Jaime R Merchan, Yixin Ren, Emmett V Schmidt, Lisa Guttman, and Sumati Gupta

Multi-center real-world data curation and assessment of tumor growth rate and overall survival in advanced NSCLC treated with PD-(L)1 immune checkpoint inhibitor therapy, C Sako, Brendan Curti, Roshanthi Weerasignhe, and See all authors in comments

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A Case Report of Immune Checkpoint Inhibitor-Associated Acute Pancreatitis Presenting as Mixed DKA/HHS: Histopathological and Radiological Findings, Amanda Sams

Immune Pathway Antagonists, R Sanborn