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Submissions from 2024

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Let's Put AI to Really Good Use!, Jens R Chapman, Jeff Wang, and Karsten Wiechert

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Cannabis Use Disorder Trends and Health Care Utilization After Cervical and Lumbar Spine Fusions., Nicholas Dietz, Victoria Alkin, Nitin Agarwal, Mayur Sharma, Brent Garrison Oxford, Dengzhi Wang, Beatrice Ugiliweneza, Jersey Mettille, Maxwell Boakye, and Doniel Drazin

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Infarct Evolution on MR-DWI After Thrombectomy in Acute Stroke Patients Randomized to Nerinetide or Placebo: The REPERFUSE-NA1 Study., Joachim Fladt, Jen Guo, Jacinta L Specht, Meng Wang, Leona L Chan, Ryan Mctaggart, Brian H Buck, Richard Aviv, Richard H Swartz, Thalia S Field, Jason Tarpley, Ruchir Shah, Mayank Goyal, Michael Tymianski, Michael D Hill, Andrew Demchuk, Christopher d'Esterre, and Philip Barber

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The RAPID Consortium: A Platform for Clinical and Translational Pituitary Tumor Research., Michael Karsy, Varun Kshettry, Paul Gardner, Michael Chicoine, Juan C Fernandez-Miranda, James J Evans, Garni Barkhoudarian, Douglas Hardesty, Won Kim, Gabriel Zada, Tomiko Crocker, Ildiko Torok, and Andrew Little

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Pilot Study of High-Dose Pemetrexed in Patients with Progressive Chordoma., Santosh Kesari, Naveed Wagle, Jose Carrillo, Akanksha Sharma, Minhdan Nguyen, Judy D Truong, Jaya Mini Gill, Raffi Nersesian, Natsuko Nomura, Elnaz Rahbarlayegh, Garni Barkhoudarian, Walavan Sivakumar, Daniel F Kelly, Howard Krauss, Matias A Bustos, Dave Hoon, Lars Anker, Arun S Singh, Kamalesh K Sankhala, and Tiffany Juarez

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The Dance Between Tumor Molecular Biology and Antitumor Immune Response., K A Margolin

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Exercise-Related Physical Activity Relates to Brain Volumes in 10,125 Individuals., Cyrus A Raji, Somayeh Meysami, Sam Hashemi, Saurabh Garg, Nasrin Akbari, Gouda Ahmed, Yosef Gavriel Chodakiewitz, Thanh Duc Nguyen, Kellyann Niotis, David A Merrill, and Rajpaul Attariwala

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Analysis of 10-year trends in Medicare Physician Fee Schedule payments in surgery., Udai S Sibia, Janelle-Cheri Millen, John R Klune, Anton Bilchik, and Leland J Foshag

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Management of Neurologic Complications in Patients with Brain and Spine Tumors., Alipi V Bonm and Lynne P Taylor

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Persistent Lower Extremity Compensation for Sagittal Imbalance After Surgical Correction of Complex Adult Spinal Deformity: A Radiographic Analysis of Early Impact., Tyler K Williamson, Pooja Dave, Jamshaid M Mir, Justin S Smith, Renaud Lafage, Breton Line, Bassel G Diebo, Alan H Daniels, Jeffrey L Gum, Themistocles S Protopsaltis, D Kojo Hamilton, Alex Soroceanu, Justin K Scheer, Robert Eastlack, Michael P Kelly, Pierce Nunley, Khaled M Kebaish, Stephen Lewis, Lawrence G Lenke, Richard A Hostin, Munish C Gupta, Han Jo Kim, Christopher P Ames, Robert A Hart, Douglas C Burton, Christopher I Shaffrey, Eric O Klineberg, Frank J Schwab, Virginie Lafage, Dean Chou, Kai-Ming Fu, Shay Bess, Peter G Passias, and International Spine Study Group

Submissions from 2023

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Heterogeneity in the Metastatic Microenvironment: JunB-Expressing Microglia Cells as Potential Drivers of Melanoma Brain Metastasis Progression., Orit Adir, Orit Sagi-Assif, Tsipi Meshel, Shlomit Ben-Menachem, Metsada Pasmanik-Chor, Dave Hoon, Isaac P Witz, and Sivan Izraely

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Comprehensive Venous Outflow Predicts Functional Outcomes in Patients with Acute Ischemic Stroke Treated by Thrombectomy., G Adusumilli, T D Faizy, S Christensen, M Mlynash, Yince Loh, G W Albers, M G Lansberg, J Fiehler, and J J Heit

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Determining the best vertebra for measuring pelvic incidence and spinopelvic parameters in adult spinal deformity patients with transitional anatomy., Fares Ani, Themistocles S Protopsaltis, Yesha Parekh, Khalid Odeh, Renaud Lafage, Justin S Smith, Robert K Eastlack, Lawrence Lenke, Frank Schwab, Gregory M Mundis, Munish C Gupta, Eric O Klineberg, Virginie Lafage, Robert A Hart, Douglas Burton, Christopher P Ames, Christopher I Shaffrey, and Shay Bess

Motor Potentials Evoked from Globus Pallidus Interna Leads Indicate Capsular Proximity During Asleep Deep Brain Stimulation for Parkinson's Disease, H Anwar, Alyx Lesko, and See all authors in comments

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Retinal mid-peripheral capillary free zones are enlarged in cognitively unimpaired older adults at high risk for Alzheimer's disease., Edmund Arthur, Swetha Ravichandran, Peter J Snyder, Jessica Alber, Jennifer Strenger, Ava K Bittner, Rima Khankan, Stephanie L Adams, Nicole M Putnam, Karin R Lypka, Juan A Piantino, and Stuart Sinoff

Does Atrial Fibrillation (Afib) Impact The Rate Of 90 Days Modified Rankin Scale (mRS) In Patients Who Received Intravenous Thrombolytic (IVT) Before Endovascular Treatment (EVT)? Results From A Large Health System In Six Western States Of The US, R Bavarsad Shahripour, Alyx Lesko, and See all authors in comments

Does History Of Atrial Fibrillation (Afib) Impact TICI Scores In Acute Ischemic Stroke Patients Receiving Endovascular Treatment With Or Without IV Thrombolytics? Results From A Large Health System In Six Western States Of The United States, R Bavarsad Shahripour, Alyx Lesko, and See all authors in comments

The Impact Of Atrial Fibrillation (Afib) On The Discharge Disposition In Patients Who Received Acute Stroke Intervention Therapies. Results from A Large Health System In Six Western States Of The United States, R Bavarsad Shahripour, Alyx Lesko, and See all authors in comments

Retrospective Safety Study of Low Intensity Monitoring In Cases of Acute Ischemic Stroke That Received Thrombolytic Therapy, Y Bello, Alyx Lesko, and See all authors in comments

Enhancing Anti-tumor Immunity for the Treatment of Head and Neck Cancer, RB Bell

Enhancing Anti-tumor Immunity for the Treatment of Head and Neck Cancer, RB Bell

Neoadjuvant Immunoradiotherapy Prior to Surgery: Towards a New Paradigm in the Management of Locally Advanced Head and Neck Cancer, RB Bell

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Would you do it again? Discrepancies between patient and surgeon perceptions following adult spine deformity surgery., Shay Bess, Breton Line, Christopher Ames, Douglas Burton, Gregory Mundis, Robert Eastlack, Robert A Hart, Munish Gupta, Eric Klineberg, Han Jo Kim, Richard Hostin, Khaled Kebaish, Virgine Lafage, Renaud Lafage, Frank Schwab, Christopher Shaffrey, and Justin S Smith

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Postoperative Discharge to Acute Rehabilitation or Skilled Nursing Facility Compared to Home Does Not Reduce Hospital Readmissions, Return to Surgery or Improve Outcomes Following Adult Spine Deformity Surgery., Shay Bess, Breton G Line, Pierce Nunley, Christopher Ames, Douglas Burton, Gregory Mundis, Robert Eastlack, Robert A Hart, Munish Gupta, Eric Klineberg, Han Jo Kim, Michael Kelly, Richard Hostin, Khaled Kebaish, Virgine Lafage, Renaud Lafage, Frank Schwab, Christopher Shaffrey, Justin S Smith, and International Spine Study Group

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Impact of Eating a Carbohydrate-Restricted Diet on Cortical Atrophy in a Cross-Section of Amyloid Positive Patients with Alzheimer's Disease: A Small Sample Study., Jennifer Bramen, Prabha Siddarth, Emily S Popa, Gavin T Kress, Molly Rapozo, John F Hodes, Aarthi Ganapathi, Colby B Slyapich, Ryan M. Glatt, Kyron P Pierce, Verna R Porter, Claudia L Wong, Mihae Kim, Richelin V Dye, Stella Panos, Tess Bookheimer, Tori Togashi, Spencer Loong, Cyrus A Raji, Susan Y Bookheimer, Jared C Roach, and David A Merrill

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Non-Invasive Transcutaneous Afferent Patterned Stimulation Therapy Offers Action Tremor Relief in Parkinson's Disease., Salima Brillman, Pravin Khemani, Stuart H Isaacson, Rajesh Pahwa, Ruta Deshpande, Vivien Zraick, Apoorva Rajagopal, Dhira Khosla, and Kathryn H Rosenbluth

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The aging brain: risk factors and interventions for long term brain health in women., Jessica Z K Caldwell and Nancy B. Isenberg

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High-dose vitamin D3 supplementation in relapsing-remitting multiple sclerosis: a randomised clinical trial, Sandra D Cassard, Kathryn C Fitzgerald, Peiqing Qian, Susan A Emrich, Christina J Azevedo, Andrew D Goodman, Elizabeth A Sugar, Daniel Pelletier, Emmanuelle Waubant, and Ellen M Mowry

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Longitudinal Changes in Cognitive Test Scores in Patients With Relapsing Remitting Multiple Sclerosis: An Analysis of the DECIDE Dataset., Nina Castrogiovanni, Jop Mostert, Pavle Repovic, James D Bowen, Bernard M J Uitdehaag, Eva M M Strijbis, Gary R Cutter, and Marcus W Koch

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Binned Data Provide Better Imputation of Missing Time Series Data from Wearables., Shweta Chakrabarti, Nupur Biswas, Khushi Karnani, Vijay Padul, Lawrence D Jones, Santosh Kesari, and Shashaanka Ashili

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Morphoelectric and transcriptomic divergence of the layer 1 interneuron repertoire in human versus mouse neocortex., Thomas Chartrand, Rachel Dalley, Jennie Close, Natalia A Goriounova, Brian R Lee, Rusty Mann, Jeremy A Miller, Gabor Molnar, Alice Mukora, Lauren Alfiler, Katherine Baker, Trygve E Bakken, Jim Berg, Darren Bertagnolli, Thomas Braun, Krissy Brouner, Tamara Casper, Eva Adrienn Csajbok, Nick Dee, Tom Egdorf, Rachel Enstrom, Anna A Galakhova, Amanda Gary, Emily Gelfand, Jeff Goldy, Kristen Hadley, Tim S Heistek, DiJon Hill, Nik Jorstad, Lisa Kim, Agnes Katalin Kocsis, Lauren Kruse, Michael Kunst, Gabriela Leon, Brian Long, Matthew Mallory, Medea McGraw, Delissa McMillen, Erica J Melief, Norbert Mihut, Lindsay Ng, Julie Nyhus, Gáspár Oláh, Attila Ozsvár, Victoria Omstead, Zoltan Peterfi, Alice Pom, Lydia Potekhina, Ramkumar Rajanbabu, Marton Rozsa, Augustin Ruiz, Joanna Sandle, Susan M Sunkin, Ildiko Szots, Michael Tieu, Martin Toth, Jessica Trinh, Sara Vargas, David Vumbaco, Grace Williams, Julia Wilson, Zizhen Yao, Pal Barzo, Charles Cobbs, Richard G Ellenbogen, Luke Esposito, Manuel Ferreira, Nathan W Gouwens, Benjamin Grannan, Ryder P Gwinn, Jason S Hauptman, Tim Jarsky, C Dirk Keene, Andrew L Ko, Christof Koch, Jeffrey G Ojemann, Anoop Patel, Jacob Ruzevick, Daniel L Silbergeld, Kimberly Smith, Staci A Sorensen, Bosiljka Tasic, Jonathan T Ting, Jack Waters, Christiaan P J de Kock, Huib D Mansvelder, Gabor Tamas, Hongkui Zeng, Brian Kalmbach, and Ed S Lein

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Sexual and Gender Diversity in Pediatric Neurology: Why We Care., Alison Christy, Jaclyn Martindale, Jennifer Hranilovich, Casey Orozco-Poore, Finley Kernan-Schloss, Chase T M Anderson, Jonathan Strober, Wendy Mitchell, and Mackenzie P Lerario

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Stand by Me: Using an Enhanced Recovery After Surgery (ERAS) Checklist to Guide Early Mobility of Postoperative Craniotomy Patients on a Progressive Care Unit, Jerome Codilla, Alyssa Mooney, Joanna Arraiza, Sohl Chapman, Nkiru Chukwudi, and Ronald Rosales

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Vertebral-Venous fistulas: Single center experience and practical treatment approach., Matias Costa, Mohammed Basamh, Juan Vivanco-Suarez, Daniel Casanova, Matias Baldoncini, Abdullah Alobaid, Yince Loh, Akshal Patel, Cameron G McDougall, and Stephen J Monteith

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Novel Technique of Head-Mounted Augmented Reality-Assisted Endovascular Neurosurgery: Proof of Concept on a Flow Model., Matias Costa, Clifford A Pierre, Mohammed Basamh, Juan Vivanco-Suarez, Matias Baldoncini, and Stephen Monteith

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Transcranial Doppler emboli monitoring for stroke prevention after flow diverting stents., Matias Costa, Paul Schmitt, Jaleel N, Matias Baldoncini, Juan Vivanco-Suarez, Colleen Douville, Yince Loh, Akshal Patel, Stephen Monteith, and Bipin Chaurasia

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Longitudinal Assessment of Modern Spine Surgery Training: 10-Year Follow-up of a Nationwide Survey of Residency and Spine Fellowship Program Directors., Alan H Daniels, Daniel Alsoof, Christopher L McDonald, Andrew S Zhang, Bassel G Diebo, Craig P Eberson, Eren O Kuris, William Lavelle, Christopher P Ames, Christopher I Shaffrey, and Robert A Hart

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Capicua (CIC) mutations in gliomas in association with MAPK activation for exposing a potential therapeutic target., Sourat Darabi, Joanne Xiu, Timothy Samec, Santosh Kesari, Jose Carrillo, Sonikpreet Aulakh, Kyle M Walsh, Soma Sengupta, Ashley Sumrall, David Spetzler, Michael Glantz, and Michael J Demeure

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Hemodynamic Management in the Prevention and Treatment of Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage., Steven Deem, Michael Diringer, Sarah Livesay, and Miriam M Treggiari

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Practical considerations when providing palliative care to patients with neuroendocrine tumors in the context of routine disease management or hospice care., Jaydira Del Rivero, Josh Mailman, Michael W Rabow, Jennifer A Chan, Sarah Creed, Hagen F Kennecke, Janice Pasieka, Jennifer Zuar, Simron Singh, and Lauren Fishbein

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Height Gain Following Correction of Adult Spinal Deformity., Bassel G Diebo, Zachary L Tataryn, Daniel Alsoof, Renaud Lafage, Robert A Hart, Peter G Passias, Christopher P Ames, Justin K Scheer, Stephen J Lewis, Christopher I Shaffrey, Douglas C Burton, Vedat Deviren, Breton G Line, Alex Soroceanu, D Kojo Hamilton, Eric O Klineberg, Gregory M Mundis, Han Jo Kim, Jeffrey L Gum, Justin S Smith, Juan S Uribe, Michael P Kelly, Khaled M Kebaish, Munish C Gupta, Pierce D Nunley, Robert K Eastlack, Richard Hostin, Themistocles S Protopsaltis, Lawrence G Lenke, Frank J Schwab, Shay Bess, Virginie Lafage, and Alan H Daniels

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Immunotherapy for brain metastases and primary brain tumors., Anna M Di Giacomo, Maximilian J Mair, Michele Ceccarelli, Andrea Anichini, Ramy Ibrahim, Michael Weller, Michael Lahn, Alexander M M Eggermont, Bernard Fox, and Michele Maio

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Identification and surveillance of rare relapse-initiating stem cells during complete remission post-transplantation., Marios Dimitriou, Teresa Mortera-Blanco, Magnus Tobiasson, Stefania Mazzi, Madeleine Lehander, Kari Högstrand, Mohsen Karimi, Gunilla Walldin, Monika Jansson, Sofie Vonlanthen, Per Ljungman, Saskia M C Langemeijer, Tetsuichi Yoshizato, Eva S Hellstrom-Lindberg, Petter S Woll, and Sten Eirik W Jacobsen

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Impact of Race/Ethnicity on Hospital Resource Utilization After Elective Anterior Cervical Decompression and Fusion for Degenerative Myelopathy., Jerry Y Du, Collin W Blackburn, Jens R Chapman, Nicholas U Ahn, and Randall E Marcus

Functional Outcomes in Patients with Large Vessel Occlusion Anterior Circulation Strokes Presenting with Low NIHSS Score with or without Thrombectomy Treatment, M Duncan, Alyx Lesko, and See all authors in comments

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Advancing neurosurgical education in the age of online learning and global knowledge sharing: impact of Cerebrovascular Q&A webinar series., Umme Habiba Faisal, Yassine Alami Idrissi, Bipin Chaurasia, Alexis Takasumi, Matias Baldoncini, Akshal Patel, Stephen Monteith, Cameron G McDougall, and Matias Costa

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Sensorimotor and inhibitory control in aging FMR1 premutation carriers, Heather Fielding-Gebhardt, Shannon E Kelly, Kathryn E Unruh, Lauren M Schmitt, Stormi L Pulver, Pravin Khemani, and Matthew W Mosconi

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The neuronal chromatin landscape in adult schizophrenia brains is linked to early fetal development., Kiran Girdhar, Jaroslav Bendl, Andrew Baumgartner, Karen Therrien, Sanan Venkatesh, Deepika Mathur, Pengfei Dong, Samir Rahman, Steven P Kleopoulos, Ruth Misir, Sarah M Reach, Pavan K Auluck, Stefano Marenco, David A Lewis, Vahram Haroutunian, Cory C Funk, Georgios Voloudakis, Gabriel E Hoffman, John F Fullard, and Panos Roussos

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Nature-themed video intervention may improve cardiovascular safety of psilocybin-assisted therapy for alcohol use disorder., Keith Heinzerling, Karina Sergi, Micah Linton, Rhianna Rich, Brittany Youssef, Inez Bentancourt, Jennifer Bramen, Prabha Siddarth, Louie Schwartzberg, and Daniel F Kelly

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Critical Care Management of Patients After Cardiac Arrest: A Scientific Statement from the American Heart Association and Neurocritical Care Society., Karen G Hirsch; Benjamin S Abella; Edilberto Amorim; Mary Kay Bader; Jeffrey F Barletta; Katherine Berg; Clifton W Callaway; Hans Friberg; Emily J Gilmore; David M Greer; Karl B Kern; Sarah Livesay; Teresa L May; Robert W Neumar; Jerry P Nolan; Mauro Oddo; Mary Ann Peberdy; Samuel M Poloyac; David Seder; Fabio Silvio Taccone; Anezi Uzendu; Brian Walsh; Janice L Zimmerman; Romergryko G Geocadin; and American Heart Association, Neurocritical Care Society

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Effects of baseline age and disease duration on the efficacy and safety of siponimod in patients with active SPMS: Post hoc analyses from the EXPAND study., Le H Hua, Amit Bar-Or, Stanley L Cohan, Fred D Lublin, Patricia K Coyle, Bruce Ac Cree, Xiangyi Meng, Wendy Su, Gina Mavrikis Cox, and Robert J Fox

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Seizures Following Self-Medication With Colloidal Silver: A Case Report., Daniel Hu and Cary Yuen

Take-Home Naloxone and Opioid Prescribing Patterns by Provider Specialty Type in Chronic Pain Patients: A Retrospective Study (2023, May) Poster Presented at the American Socierty for Pain and Neurology, D Ile, Alyx Lesko, and See all authors in comments

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Multi-omic profiling reveals discrepant immunogenic properties and a unique tumor microenvironment among melanoma brain metastases., Gino K In, Jennifer R Ribeiro, Jun Yin, Joanne Xiu, Matias A Bustos, Fumito Ito, Frances Chow, Gabriel Zada, Lindsay Hwang, April K S Salama, Soo J Park, Justin C Moser, Sourat Darabi, Evidio Domingo-Musibay, Maria L Ascierto, Kim Margolin, Jose Lutzky, Geoffrey T Gibney, Michael B Atkins, Benjamin Izar, Dave Hoon, and Ari M VanderWalde

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The Vicious Cycle of Melanoma-Microglia Crosstalk: Inter-Melanoma Variations in the Brain-Metastasis-Promoting IL-6/JAK/STAT3 Signaling Pathway., Sivan Izraely, Shlomit Ben-Menachem, Sapir Malka, Orit Sagi-Assif, Matias A Bustos, Orit Adir, Tsipi Meshel, Maharrish Chelladurai, Suyeon Ryu, Romela Irene Ramos, Metsada Pasmanik-Chor, Dave S B Hoon, and Isaac P Witz

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SMARTfit Dual-Task Exercise Improves Cognition and Physical Function in Older Adults With Mild Cognitive Impairment: Results of a Community-Based Pilot Study., Sameer Jhaveri, Matthew Romanyk, Ryan Glatt, and Nikhil Satchidanand

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Synergism in actions of HBV with aflatoxin in cancer development., Joshua Jin, Valentina L Kouznetsova, Santosh Kesari, and Igor F Tsigelny

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Interindividual variation in human cortical cell type abundance and expression., Nelson Johansen, Saroja Somasundaram, Kyle J Travaglini, Anna Marie Yanny, Maya Shumyatcher, Tamara Casper, Charles Cobbs, Nick Dee, Richard Ellenbogen, Manuel Ferreira, Jeff Goldy, Junitta Guzman, Ryder P Gwinn, Daniel Hirschstein, Nikolas L Jorstad, C Dirk Keene, Andrew Ko, Boaz P Levi, Jeffrey G Ojemann, Thanh Pham, Nadiya Shapovalova, Daniel Silbergeld, Josef Sulc, Amy Torkelson, Herman Tung, Kimberly Smith, Ed S Lein, Trygve E Bakken, Rebecca D Hodge, and Jeremy A Miller

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Differences in concussion knowledge between parents and their children in a multidisciplinary concussion clinic sample., Abigail Johnson, Marie Van Tubbergen, Andrew Hashikawa, Ingrid Ichesco, Andrea Almeida, Kristen Kolberg, and Jennifer Larson

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Brain volume, energy balance, and cardiovascular health in two nonindustrial South American populations., Hillard Kaplan, Paul L Hooper, Margaret Gatz, Wendy J Mack, E Meng Law, Helena C Chui, M Linda Sutherland, James D Sutherland, Christopher J Rowan, L Samuel Wann, Adel H Allam, Randall C Thompson, David E Michalik, Guido Lombardi, Michael Miyamoto, Daniel Eid Rodriguez, Juan Copajira Adrian, Raul Quispe Gutierrez, Bret A Beheim, Daniel K Cummings, Edmond Seabright, Sarah Alami, Angela R Garcia, Kenneth Buetow, Gregory S Thomas, Caleb E Finch, Jonathan Stieglitz, Benjamin C Trumble, Michael D Gurven, and Andrei Irimia

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Patient Perception of Education, Care Coordination, and Psychological Distress After Developing Facial Paralysis: A Qualitative Study., Natalie R Kenton, Merai Estafanous, Kyohei Itamura, Ania Filus, Shanthi Gowrinathan, Neil A Martin, Walavan Sivakumar, Garni Barkhoudarian, Patrick J Byrne, and Amit Kochhar

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Response to OKN-007 and NAC in a Patient with Unilateral Hearing Loss and Chronic Tinnitus from Vestibular Schwannoma., Santosh Kesari, Andy Liu, Jaya Mini Gill, Minhdan Nguyen, Judy D Truong, Raffi Nersesian, Emma Chacon, Akanksha Sharma, Naveed Wagle, Chester Griffiths, Gregory Frazer, Max Zats, Shinwook Kang, Matthew B West, Richard D Kopke, and Tiffany Juarez

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Response to OKN-007 and NAC in a Patient with Unilateral Hearing Loss and Chronic Tinnitus from Vestibular Schwannoma, Santosh Kesari, Andy Liu, Jaya Mini Gill, Minhdan Nguyen, Judy D Truong, Raffi Nersesian, Emma Chacon, Akanksha Sharma, Naveed Wagle, Chester Griffiths, Gregory Frazer, Max Zats, Shinwook Kang, Matthew B. West, Richard D. Kopke, and Tiffany Juarez

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Target cell-specific synaptic dynamics of excitatory to inhibitory neuron connections in supragranular layers of human neocortex., Mean-Hwan Kim, Cristina Radaelli, Elliot R Thomsen, Deja Monet, Thomas Chartrand, Nikolas L Jorstad, Joseph T Mahoney, Michael J Taormina, Brian Long, Katherine Baker, Trygve E Bakken, Luke Campagnola, Tamara Casper, Michael Clark, Nick Dee, Florence D'Orazi, Clare Gamlin, Brian E Kalmbach, Sara Kebede, Brian R Lee, Lindsay Ng, Jessica Trinh, Charles Cobbs, Ryder P Gwinn, C Dirk Keene, Andrew L Ko, Jeffrey G Ojemann, Daniel L Silbergeld, Staci A Sorensen, Jim Berg, Kimberly A Smith, Philip R Nicovich, Tim Jarsky, Hongkui Zeng, Jonathan T Ting, Boaz P Levi, and Ed Lein

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Relapse recovery in relapsing-remitting multiple sclerosis: An analysis of the CombiRx dataset., Marcus W Koch, Ester Moral, Luis Brieva, Jop Mostert, Eva Mm Strijbis, Jacynthe Comtois, P Repovic, J D Bowen, Jerry S Wolinsky, Fred D Lublin, and Gary Cutter

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Threshold definitions for significant change on the timed 25-foot walk and nine-hole peg test in primary progressive multiple sclerosis., Marcus W Koch, Pavle Repovic, Jop Mostert, James D Bowen, Jacynthe Comtois, Eva Strijbis, Bernard Uitdehaag, and Gary Cutter

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Structural analysis of human G-protein-coupled receptor 17 ligand binding sites., Saravanan Konda Mani, Ramesh Thiyagarajan, Olli Yli-Harja, Meenakshisundaram Kandhavelu, and Akshaya Murugesan

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Preliminary validation of a structural magnetic resonance imaging metric for tracking dementia-related neurodegeneration and future decline., Gavin T Kress, Emily S Popa, Paul M Thompson, Susan Y Bookheimer, Sophia I Thomopoulos, Christopher R K Ching, Hong Zheng, Daniel A Hirsh, David A Merrill, Stella Panos, Cyrus A Raji, Prabha Siddarth, and Jennifer E Bramen

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Trial of Globus Pallidus Focused Ultrasound Ablation in Parkinson's Disease., Vibhor Krishna, Paul S Fishman, Howard M Eisenberg, Michael Kaplitt, Gordon Baltuch, Jin Woo Chang, Wei-Chieh Chang, Raul Martinez Fernandez, Marta Del Alamo, Casey H Halpern, Pejman Ghanouni, Roberto Eleopra, Rees Cosgrove, Jorge Guridi, Ryder Gwinn, Pravin Khemani, Andres M Lozano, Nathan McDannold, Alfonso Fasano, Marius Constantinescu, Ilana Schlesinger, Arif Dalvi, and W Jeff Elias

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Signature morphoelectric properties of diverse GABAergic interneurons in the human neocortex., Brian R Lee, Rachel Dalley, Jeremy A Miller, Thomas Chartrand, Jennie Close, Rusty Mann, Alice Mukora, Lindsay Ng, Lauren Alfiler, Katherine Baker, Darren Bertagnolli, Krissy Brouner, Tamara Casper, Eva Csajbok, Nicholas Donadio, Stan L W Driessens, Tom Egdorf, Rachel Enstrom, Anna A Galakhova, Amanda Gary, Emily Gelfand, Jeff Goldy, Kristen Hadley, Tim S Heistek, Dijon Hill, Wen-Hsien Hou, Nelson Johansen, Nik Jorstad, Lisa Kim, Agnes Katalin Kocsis, Lauren Kruse, Michael Kunst, Gabriela León, Brian Long, Matthew Mallory, Michelle Maxwell, Medea McGraw, Delissa McMillen, Erica J Melief, Gabor Molnar, Marty T Mortrud, Dakota Newman, Julie Nyhus, Ximena Opitz-Araya, Attila Ozsvár, Trangthanh Pham, Alice Pom, Lydia Potekhina, Ram Rajanbabu, Augustin Ruiz, Susan M Sunkin, Ildikó Szöts, Naz Taskin, Bargavi Thyagarajan, Michael Tieu, Jessica Trinh, Sara Vargas, David Vumbaco, Femke Waleboer, Sarah Walling-Bell, Natalie Weed, Grace Williams, Julia Wilson, Shenqin Yao, Thomas Zhou, Pál Barzó, Trygve Bakken, Charles Cobbs, Nick Dee, Richard G Ellenbogen, Luke Esposito, Manuel Ferreira, Nathan W Gouwens, Benjamin Grannan, Ryder P Gwinn, Jason S Hauptman, Rebecca Hodge, Tim Jarsky, C Dirk Keene, Andrew L Ko, Anders Rosendal Korshoej, Boaz P Levi, Kaare Meier, Jeffrey G Ojemann, Anoop Patel, Jacob Ruzevick, Daniel L Silbergeld, Kimberly Smith, Jens Christian Sørensen, Jack Waters, Hongkui Zeng, Jim Berg, Marco Capogna, Natalia A Goriounova, Brian Kalmbach, Christiaan P J de Kock, Huib D Mansvelder, Staci A Sorensen, Gabor Tamas, Ed S Lein, and Jonathan T Ting

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No Delayed Ruptures on Long-Term Follow-Up of a Case Series of Persistently Filling Saccular Internal Carotid Artery Aneurysms After Flow Diversion With the Pipeline Embolization Device., Ryan P Lee, Meghana Bhimreddy, Jennifer Kim, Robert T Wicks, Risheng Xu, Matthew Bender, Wuyang Yang, Shahab Aldin Sattari, Alice Hung, Christopher M Jackson, L Fernando Gonzalez, Judy Huang, Rafael Tamargo, Cameron G McDougall, and Justin M Caplan

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Radiofrequency Ablation Provides Rapid and Durable Pain Relief for the Palliative Treatment of Lytic Bone Metastases Independent of Radiation Therapy: Final Results from the OsteoCool Tumor Ablation Post-Market Study., Jason Levy, Elizabeth David, Thomas Hopkins, Jonathan Morris, Nam D Tran, Hamed Farid, Francesco Massari, William G O'Connell, Alexander Vogel, Afshin Gangi, Peter Sunenshine, Robert Dixon, Nicolas Von der Höh, and Sandeep Bagla

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Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial., Linda M Liau, Keyoumars Ashkan, Steven Brem, Jian L Campian, John E Trusheim, Fabio M Iwamoto, David D Tran, George Ansstas, Charles Cobbs, Jason A Heth, Michael E Salacz, Stacy D'Andre, Robert D Aiken, Yaron A Moshel, Joo Y Nam, Clement P Pillainayagam, Stephanie A Wagner, Kevin A Walter, Rekha Chaudhary, Samuel A Goldlust, Ian Y Lee, Daniela A Bota, Heinrich Elinzano, Jai Grewal, Kevin Lillehei, Tom Mikkelsen, Tobias Walbert, Steven Abram, Andrew J Brenner, Matthew G Ewend, Simon Khagi, Darren S Lovick, Jana Portnow, Lyndon Kim, William G Loudon, Nina L Martinez, Reid C Thompson, David E Avigan, Karen L Fink, Francois J Geoffroy, Pierre Giglio, Oleg Gligich, Dietmar Krex, Scott M Lindhorst, Jose Lutzky, Hans-Jörg Meisel, Minou Nadji-Ohl, Lhagva Sanchin, Andrew Sloan, Lynne P Taylor, Julian K Wu, Erin M Dunbar, Arnold B Etame, Santosh Kesari, David Mathieu, David E Piccioni, David S Baskin, Michel Lacroix, Sven-Axel May, Pamela Z New, Timothy J Pluard, Steven A Toms, Victor Tse, Scott Peak, John L Villano, James D Battiste, Paul J Mulholland, Michael L Pearlman, Kevin Petrecca, Michael Schulder, Robert M Prins, Alton L Boynton, and Marnix L Bosch

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Long-term survival after salvage pemetrexed for refractory primary T-cell lymphoma of the CNS., Andy Liu, Huda Alalami, Xuemo Fan, Chirag Patil, Jaya M Gill, Santosh Kesari, and Jethro Hu

Poster Presented at the International Stroke Conference, T Lowenkopf, Alyx Lesko, and See all authors in comments

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Neuroinflammation: A Modifiable Pathway Linking Obesity, Alzheimer's disease, and Depression., Maria Ly, Gary Z Yu, Ali Mian, Austin Cramer, Somayeh Meysami, David A Merrill, Amjad Samara, Sarah A Eisenstein, Tamara Hershey, Ganesh M Babulal, Eric J Lenze, John C Morris, Tammie L S Benzinger, and Cyrus A Raji

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A prospective multi-center observational study of surgical versus non-surgical management for pituitary apoplexy., Adam N Mamelak, Andrew S Little, Paul A Gardner, João Paulo Almeida, Pablo Recinos, Pranay Soni, Varun R Kshettry, John A Jane, Garni Barkhoudarian, Daniel F Kelly, Robert Dodd, Debraj Mukherjee, Zachary C Gersey, Noriaki Fukuhara, Hiroshi Nishioka, Eui-Hyun Kim, Claude-Fabien Litré, Elliott Sina, Mia W Mazer, Yujie Cui, and Vivien Bonert

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Treatment of adult deformity surgery by orthopedic and neurological surgeons: trends in treatment, techniques, and costs by specialty., Christopher L McDonald, Rodrigo A Saad Berreta, Daniel Alsoof, Alex Homer, Janine Molino, Christopher P Ames, Christopher I Shaffrey, D Kojo Hamilton, Bassel G Diebo, Eren O Kuris, Robert A Hart, and Alan H Daniels

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A combined exercise and cognitive training intervention induces fronto-cingulate cortical plasticity in first-episode psychosis patients., S C McEwen, B Jarrahi, J Ventura, K L Subotnik, J Nguyen, S M Woo, and K H Nuechterlein

Multicenter Flow Diversion for Intracranial Aneurysms: Intracranial Hemorrhage & Thromboembolic Complications In A Multi-Center Cohort of 200 Patients, R Meister, Alyx Lesko, and See all authors in comments

Multicenter Flow Diversion in 200 individuals for treatment of intracranial aneurysms, R Meister, Alyx Lesko, and See all authors in comments

Characterizing cancer’s dark matter, short-lived proteins, and defective ribosomal products, presented by cancer and contained in the DPV-001 cancer vaccine, R Meng, Will Redmond, Carlo Bifulco, Rachel Sanborn, RB Bell, Walter Urba, Rom Leidner, Brian Piening, Bernard Fox, and See full list of authors in comments

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Novel TCF4:TCF12 heterodimer inhibits glioblastoma growth., Svetlana A Mikheeva, Cory C Funk, Philip J Horner, Robert C Rostomily, and Andrei M Mikheev

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A Guide to Expanding the Use of Buprenorphine Beyond Standard Initiations for Opioid Use Disorder., James Miller, Michael A Brooks, Kelly Wurzel, Emily J Cox, and John F Wurzel

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Clinical Practice Panel: Stand by Me: Using an Enhanced Recovery After Surgery (ERAS)Checklist to Guide Early Mobility of Postoperative Craniotomy Patients on a Progressive Care Unit, Alyssa Mooney, Jerome Codilla, Joanna Arraiza, Sohl Chapman, Nkiru Chukwudi, and Ronald Rosales

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Stereotactic and Functional Neurosurgery Convection-Enhanced Delivery of Autologous Cerebrospinal Fluid Enhances Basal Ganglia Visualization during MRI-Guided Deep Brain Stimulation Surgery., Shayan Moosa, Aaron E Bond, Tony R Wang, Faraz Farzad, Ashok R Asthagiri, and W Jeffrey Elias

PD-1 expression on tumor-infiltrating T-lymphocytes as determinant of the head and neck cancer tumor immune microenvironment rather than anatomical site, T Muijlwijk, Bernard Fox, and See full list of authors in comments

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Preliminary experience with a novel facet-based lateral mass drill guide for the placement of lateral mass screws compared to freehand technique: a cadaveric study., Gregory M Mundis, Eric C Olsson, Robert A Hart, Seth K Williams, Ryan Martyn, Douglas G Orndorff, Anastasia L Berg, Nicholas A Russell, and Frank Vizesi

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External Validation of an Artificial Intelligence Device for Intracranial Hemorrhage Detection., Gabriel Neves, Pranav I Warman, Anmol Warman, Roshan Warman, Tulio Bueso, Jason D Vadhan, and Thomas Windisch

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Optimum duration of hyperventilation during electroencephalography., Kalarickal J Oommen and Jonathan Kopel

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TN-RS: a novel scoring system predicts Gamma Knife Radiosurgery outcome for trigeminal neuralgia patients., Alon Orlev, James Feghali, Gil Kimchi, Lian Sun, Clifford A Pierre, Cristian Gragnaniello, Cristian Cotrutz, Christopher Loiselle, Sandra Vermeulen, and Zachary Litvack

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Mechanical Venous Thrombectomy Using Indigo Aspiration System: A Case Report., Riichi A Ota, Gabriel Neves, Victor C Montalvan, Thomas Windisch, and Saif Bushnaq

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The impact of baseline cervical malalignment on the development of proximal junctional kyphosis following surgical correction of thoracolumbar adult spinal deformity., Lara Passfall, Bailey Imbo, Virginie Lafage, Renaud Lafage, Justin S Smith, Breton Line, Andrew J Schoenfeld, Themistocles Protopsaltis, Alan H Daniels, Khaled M Kebaish, Jeffrey L Gum, Heiko Koller, D Kojo Hamilton, Richard Hostin, Munish Gupta, Neel Anand, Christopher P Ames, Robert Hart, Douglas Burton, Frank J Schwab, Christopher I Shaffrey, Eric O Klineberg, Han Jo Kim, Shay Bess, and Peter G Passias

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Economic burden of nonoperative treatment of adult spinal deformity., Peter G Passias, Waleed Ahmad, Pooja Dave, Renaud Lafage, Virginie Lafage, Jamshaid Mir, Eric O Klineberg, Khaled M Kabeish, Jeffrey L Gum, Breton G Line, Robert A Hart, Douglas Burton, Justin S Smith, Christopher P Ames, Christopher I Shaffrey, Frank Schwab, Richard Hostin, Thomas Buell, D Kojo Hamilton, and Shay Bess

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Identifying Subsets of Patients With Adult Spinal Deformity Who Maintained a Positive Response to Nonoperative Management., Peter G Passias, Waleed Ahmad, Peter Tretiakov, Oscar Krol, Frank Segreto, Renaud Lafage, Virginie Lafage, Alex Soroceanu, Alan Daniels, Jeffrey Gum, Breton Line, Andrew J Schoenfeld, Shaleen Vira, Robert Hart, Douglas Burton, Justin S Smith, Christopher P Ames, Christopher Shaffrey, Frank Schwab, Shay Bess, and International Spine Study Group

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Critical Analysis of Radiographic and Patient Reported Outcomes Following Anterior/Posterior Staged vs. Same Day Surgery in Patients Undergoing Identical Corrective Surgery for Adult Spinal Deformity., Peter G Passias, Waleed Ahmad, Peter S Tretiakov, Renaud Lafage, Virginie Lafage, Andrew J Schoenfeld, Breton Line, Alan Daniels, Jamshaid M Mir, Munish Gupta, Gregory Mundis, Robert Eastlack, Pierce Nunley, D Kojo Hamilton, Richard Hostin, Robert Hart, Douglas C Burton, Christopher Shaffrey, Frank Schwab, Christopher Ames, Justin S Smith, Shay Bess, Eric O Klineberg, and International Spine Study Group

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Efficacy of Varying Surgical Approaches on Achieving Optimal Alignment in Adult Spinal Deformity Surgery., Peter G Passias, Waleed Ahmad, Tyler K Williamson, Jordan Lebovic, Khaled Kebaish, Renaud Lafage, Virginie Lafage, Breton Line, Andrew J Schoenfeld, Bassel G Diebo, Eric O Klineberg, Han Jo Kim, Christopher P Ames, Alan H Daniels, Justin S Smith, Christopher I Shaffrey, Douglas C Burton, Robert A Hart, Shay Bess, Frank J Schwab, Munish C Gupta, and International Spine Study Group

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Patient-specific Cervical Deformity Corrections With Consideration of Associated Risk: Establishment of Risk Benefit Thresholds for Invasiveness Based on Deformity and Frailty Severity., Peter G Passias, Katherine E Pierce, Tyler K Williamson, Jordan Lebovic, Andrew J Schoenfeld, Renaud Lafage, Virginie Lafage, Jeffrey L Gum, Robert Eastlack, Han Jo Kim, Eric O Klineberg, Alan H Daniels, Themistocles S Protopsaltis, Gregory M Mundis, Justin K Scheer, Paul Park, Dean Chou, Breton Line, Robert A Hart, Douglas C Burton, Shay Bess, Frank J Schwab, Christopher I Shaffrey, Justin S Smith, and Christopher P Ames

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Incremental benefits of circumferential minimally invasive surgery for increasingly frail patients with adult spinal deformity., Peter G Passias, Peter S Tretiakov, Pierce D Nunley, Michael Y Wang, Paul Park, Adam S Kanter, David O Okonkwo, Robert K Eastlack, Gregory M Mundis, Dean Chou, Nitin Agarwal, Richard G Fessler, Juan S Uribe, Neel Anand, Khoi D Than, Gregory Brusko, Kai-Ming Fu, Jay D Turner, Vivian P Le, Breton G Line, Christopher P Ames, Justin S Smith, Christopher I Shaffrey, Robert A Hart, Douglas Burton, Renaud Lafage, Virginie Lafage, Frank Schwab, Shay Bess, and Praveen V Mummaneni

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Cost Benefit of Implementation of Risk Stratification Models for Adult Spinal Deformity Surgery., Peter G Passias, Tyler K Williamson, Nicholas A Kummer, Ferran Pellisé, Virginie Lafage, Renaud Lafage, Miguel Serra-Burriel, Justin S Smith, Breton Line, Shaleen Vira, Jeffrey L Gum, Sleiman Haddad, Francisco Javier Sánchez Pérez-Grueso, Andrew J Schoenfeld, Alan H Daniels, Dean Chou, Eric O Klineberg, Munish C Gupta, Khaled M Kebaish, Michael P Kelly, Robert A Hart, Douglas C Burton, Frank Kleinstück, Ibrahim Obeid, Christopher I Shaffrey, Ahmet Alanay, Christopher P Ames, Frank J Schwab, Richard A Hostin, Shay Bess, and International Spine Study Group