Submissions from 2025
Benefits of Supplementing a GLP-1 Type Medication With Physical Activity., Elizabeth Ablah, Mary T Imboden, Anna L Zendell, Michael Hosking, Robert E Anderson, Kipchoge VanHoose, Neil Peterson, Janet R Wojcik, Nicolaas P Pronk, Murray Harber, and Laurie P Whitsel
Tirzepatide Associated With Reduced Albuminuria in Participants With Type 2 Diabetes: Pooled Post Hoc Analysis From the Randomized Active- and Placebo-Controlled SURPASS-1-5 Clinical Trials., Ellen M Apperloo, Katherine Tuttle, Imre Pavo, Axel Haupt, Rebecca Taylor, Russell J Wiese, Andrea Hemmingway, David Z I Cherney, Naveed Sattar, and Hiddo J L Heerspink
Cognitive effects of ocrelizumab vs interferon β-1a in relapsing multiple sclerosis: A post hoc analysis of the OPERA I/II trials., Ralph Hb Benedict, Ludwig Kappos, Aaron Miller, Hans-Peter Hartung, James Overell, Jinglan Pei, Frank Dahlke, Corrado Bernasconi, Harold Koendgen, Qing Wang, Ulrike Bonati, and Stanley Cohan
Risk of Long COVID in hospitalized individuals treated with remdesivir for acute COVID-19., Mark Berry, Amanda M Kong, Roger Paredes, Julie Paone, Rohan Shah, Rebecca Taylor, Essy Mozaffari, Rikisha Gupta, Robert L Gottlieb, Lourdes Mateu, Mazin Abdelghany, Jason D Goldman, and Anand P Chokkalingam
Prevalence and Associations of Systemic Inflammation in Heart Failure Across the Spectrum of Ejection Fraction., Barry A Borlaug, Cecilie Holse, Mette Holme Jung, A Michael Lincoff, Sharon L Mulvagh, Jacob Stærk-Østergaard, Katherine R Tuttle, and Mark C Petrie
The Pharmacogenomics Global Research Network Implementation Working Group: global collaboration to advance pharmacogenetic implementation., Larisa H Cavallari, J Kevin Hicks, Jai N Patel, Amanda L Elchynski, D Max Smith, Salma A Bargal, Ashley Fleck, Christina L Aquilante, Shayna R Killam, Lauren Lemke, Taichi Ochi, Laura B Ramsey, Cyrine E Haidar, Teresa Ho, Nihal El Rouby, Andrew A Monte, Josiah D Allen, Amber L Beitelshees, Jeffrey R Bishop, Chad Bousman, Ronald Campbell, Emily J Cicali, Kelsey J Cook, Benjamin Duong, Evangelia Eirini Tsermpini, Sonya Tang Girdwood, David B Gregornik, Kristin N Grimsrud, Nathan Lamb, James C Lee, Rocio Ortiz Lopez, Tinashe Adrian Mazhindu, Sarah A Morris, Mohamed Nagy, Jenny Nguyen, Amy L Pasternak, Natasha Petry, Ron H N van Schaik, April Schultz, Todd C Skaar, Hana Al Alshaykh, James M Stevenson, Rachael M Stone, Nam K Tran, Sony Tuteja, Erica L Woodahl, Li-Chi Yuan, and Craig R Lee
Evaluation of the Toxicity and Outcomes of the Combination of Midostaurin and CLAG-M in Patients With FLT3-Mutated Acute Myeloid Leukemia (AML): A Multicenter Retrospective Analysis., Ashley Chen, Grace Baek, Kathryn Russell, Carole Shaw, Megan Othus, Jonathan Cohen, Shannon Palmer, Jack Rasmussen, Joseph Bubalo, Tenzin Tsomo, Tenley Schwarz, Swathi Namburi, and Anna Halpern
Respect Rx Remedy: Dosage of Decency, Decreasing Bullying and Incivility, Sophia Corso, Olivia Edwards, Elise Kimball, Lillie Le, and Hannah Sauer
Longitudinal Genomic Analysis to Fine-Tune Targeted Therapy: Results of the Phase II LOGIC 2 Trial in Patients With BRAF V600-Mutant Metastatic Melanoma., Reinhard Dummer, Shahneen Sandhu, Wilson H Miller, Marcus O Butler, Matthew H Taylor, Lucie Heinzerling, Christian U Blank, Eva Munoz-Couselo, Howard A Burris, Michael A Postow, Bartosz Chmielowski, Mark R Middleton, Carola Berking, Jessica C Hassel, Anja Heike Gesierich, Cornelia Mauch, Joseph F Kleha, Anna Polli, Allison S Harney, Alessandra di Pietro, and Paolo A Ascierto
Long-Term Safety and Effectiveness of Sebetralstat: Interim Analysis of KONFIDENT-S Open-label Extension., Henriette Farkas, John Anderson, Laurence Bouillet, Teresa Caballero, Mauro Cancian, Timothy Craig, Atsushi Fukunaga, Vesna Grivcheva-Panovska, Mar Guilarte, Daisuke Honda, Henry Kanarek, Sorena Kiani-Alikhan, Tamar Kinaciyan, Damia Leguevaques, Hilary J Longhurst, Markus Magerl, Michael E Manning, Inmaculada Martinez-Saguer, Isaac Melamed, Maeve E O'Connor, Jonny Peter, Sinisa Savic, Daniel F Soteres, Maria Staevska, Petra Staubach, Marcin Stobiecki, Raffi Tachdjian, Anna Valerieva, Patrick F K Yong, James Hao, Matthew Iverson, Michael D Smith, Christopher M Yea, Paul K Audhya, Emel Aygören-Pürsün, Jonathan A Bernstein, Danny M Cohn, William R Lumry, Marc A Riedl, Andrea Zanichelli, and Marcus Maurer
Inhibitors of soluble epoxide hydrolase and cGAS/STING repair defects in amyloid-β clearance underlying vascular complications of Alzheimer's disease., Milan Fiala, Bruce D Hammock, Sung Hee Hwang, Julian Whitelegge, Ketema Paul, Karolina Elżbieta Kaczor-Urbanowicz, Andrzej Urbanowicz, and Santosh Kesari
Engineering noncovalent π-stacked organic framework for intrinsic near-infrared photoactivated drug delivery., Ruxing Fu, Dong Meng, Xiao Han, Lu Liu, Chichia Chen, Ran Zheng, Yepin Zhao, Xuexiang Zhang, Xiao Lin, Mahdi Hasani, Yang Song, Tingxizi Liang, Di Wen, Hongjun Li, Ilhan Yavuz, Huiheng Feng, Zhen Gu, Zhenxing Li, Song Li, Feng Liu, and Yang Yang
Antimicrobial Therapy for Pseudomonas aeruginosa., Joshua A Garcia
Induced pluripotent stem-cell-derived CD19-directed chimeric antigen receptor natural killer cells in B-cell lymphoma: a phase 1, first-in-human trial., Armin Ghobadi, Veronika Bachanova, Krish Patel, Jae H Park, Ian Flinn, Peter A Riedell, Carlos Bachier, Catherine S Diefenbach, Carol Wong, Cara Bickers, Lilly Wong, Deepa Patel, Jode Goodridge, Matthew Denholt, Bahram Valamehr, Rebecca L Elstrom, and Paolo Strati
Effect of Bimekizumab on Patient-Reported Outcomes and Work Productivity in Patients With Psoriatic Arthritis: 1-Year Results From 2 Phase III Studies., Dafna D Gladman, Philip Mease, Laure Gossec, M Elaine Husni, Alice B Gottlieb, Barbara Ink, Rajan Bajracharya, Jason Coarse, Nikos Lyris, Jérémy Lambert, and William Tillett
Examining the effect of a Whole Health Primary Care Pain Education and Opioid Monitoring Program (PC-POP) at preventing opioid-induced constipation., Taylor Hammack, Clayton J Hamilton, and Amber Martinson
Trends in Pharmacological Treatment of Patients With New Onset Type 2 Diabetes: Usage Patterns in an Evolving Guideline Landscape., William Hou, Katherine R Tuttle, Weining Shen, Andrew Reikes, and Jonathan H Watanabe
The relationship between sleep and academic performance among multiple health care training programs., Henry Hua, Tawnya Kargupta, Kim Vo, Karen Chang, and Joy Takahashi
Short-term mortality after opioid initiation among opioid-naïve and non-naïve patients with dementia: a retrospective cohort study., Yeon-Mi Hwang, Jennifer M Hah, Jennifer Bramen, Jennifer J Hadlock, and Tina Hernandez-Boussard
Access to GLP-1s: Where Do Employers Fit in?, Mary T Imboden
Knowing Well, Being Well: well-being born of understanding: Access to GLP-1s: Where Do Employers Fit in?, Mary T Imboden
Expert Perspectives on Controversies and Critical Knowledge Gaps in Breast Cancer Management: Proceedings of the First Bridging the Gaps in Breast Cancer Symposium., Komal Jhaveri, Carey K Anders, Aditya Bardia, Manali Bhave, A Jo Chien, Ian Krop, Tiffany A Traina, Yara Abdou, Reva Basho, Alison K Conlin, Francisco J Esteva, Kevin R Fox, Vijayakrishna Gadi, Peter A Kaufman, Anya Litvak, Cynthia X Ma, Eleftherios P Mamounas, Heather McArthur, Kelly McCann, Zahi Mitri, Rebecca Shatsky, Melinda Telli, Mylin A Torres, and Kevin Kalinsky
Successful Treatment of Candida auris Ventriculitis With Intravenous Liposomal Amphotericin B and Oral Flucytosine: A Case Report, Nayoung Kang, Victor Yu-Ching Hsu, and Charles Christopher Bailey
Patterns of Prophylactic Anticoagulation Among Patients Hospitalized for COVID-19: An Analysis of the American Heart Association COVID-19 Cardiovascular Disease Registry., Mathew S Lopes, Hsin-Fang Li, Reed J D Sorensen, Sandeep Das, Steven M Bradley, James A de Lemos, Gregory A Roth, Tracy Wang, Erin A Bohula, and Ty J Gluckman
Real-World Safety and Effectiveness of Dimethyl Fumarate in Patients with MS: Results from the ESTEEM Phase 4 and PROCLAIM Phase 3 Studies with a Focus on Older Patients., Yang Mao-Draayer, Amit Bar-Or, Konstantin Balashov, John Foley, Kyle E Smoot, Erin E Longbrake, Derrick Robertson, Jason P Mendoza, James B Lewin, Nicholas Everage, Ivan Božin, Jennifer Lyons, Oksana Mokliatchouk, Eris Bame, and Fabrizio Giuliani
Relationship of radiographic progression status to low disease activity in patients with psoriatic arthritis receiving secukinumab treatment for two years., Philip J Mease, Laura C Coates, Corine Gaillez, Alexis Shew, Weibin Bao, and Christopher T Ritchlin
GLP-1 receptor agonists for weight loss for perimenopausal and postmenopausal women: current evidence., Hana Mikdachi and Rebecca Dunsmoor-Su
Long-Term Outcomes of Radiation Monotherapy Versus Combined Radiation Monotherapy + Hormone Therapy in Low-Risk Early-Stage Breast Cancer Patients 70 Years or Older After Breast-Conserving Surgery., Astrid D Morris, Douglas Hanes, and Henry G Kaplan
Ivermectin and gynecologic cancer: What's the data?, Vaidehi Mujumdar, Marilyn Huang, Lindsey Chippendale Smith, and Fernanda Musa
Incidence and Outcomes of Atrial Fibrillation and Systolic Dysfunction in Patients Receiving Mavacamten for Obstructive Hypertrophic Cardiomyopathy: A Multicenter Study., Olives Nguyen, Jack Wiedrick, Daniele Massera, Elizabeth Adlestein, Sumar Frejat, Matteo Castrichini, Said Alsidawi, John R Giudicessi, Jeffrey B Geske, Richard T Carrick, Jose Madrazo, Nicole Dellise, Mark A Zenker, Thomas A Boyle, Nosheen Reza, Anjali Tiku Owens, David S Frankel, Prabhjot Hundal, Jamil Tajik, Patrycja Galazka, Myra Lewontin, Michael Ayers, Timothy Wong, Michael Flanagan, Sumeet Singh Mitter, Arjun Kanwal, Ozlem Bilen, Sarah Baghdadi, Hirak Shah, Jared Kvapil, Paola Roldan, Loren Berenbom, Jill Jesurum, Denise Tootill, Alice Siqueira-Benzow, Mariko Harper, Danish Saleh, Lubna Choudhury, Isabela Valenta, Melissa Lang, Dermot M Phelan, Dmitry Prizand, Neal Lakdawala, Carolyn Y Ho, Lusha W Liang, Shepard D Weiner, Sririam Ravi, Ahmed Sami Abuzaid, Mohammed Makkiya, Jeremy S Markowitz, Mark Sherrid, and Ahmad Masri
Once-daily versus twice-daily oral vancomycin for secondary prevention of Clostridioides difficile infection in patients treated with systemic antibiotics, Catherine Palmer
The NLS3 Motif in TPX2 Regulates Spindle Architecture in Xenopus Egg Extracts., Guadalupe E Pena, Xiao Zhou, Lauren Slevin, Christopher Brownlee, and Rebecca Heald
Safety and efficacy of acalabrutinib plus bendamustine and rituximab in patients with treatment-naïve or relapsed/refractory mantle cell lymphoma: phase Ib trial., Tycel Phillips, Michael Wang, Tadeusz Robak, David Gallinson, Don Stevens, Krish Patel, Safaa Ramadan, Chuan-Chuan Wun, Wojciech Jurczak, and Stephen D Smith
Verdiperstat in Amyotrophic Lateral Sclerosis: Results From the Randomized HEALEY ALS Platform Trial., Writing Committee for the HEALEY ALS Platform Trial, Jinsy Andrews, Sabrina Paganoni, Eric A Macklin, Lori B Chibnik, Melanie Quintana, Benjamin R Saville, Michelle A Detry, Matteo Vestrucci, Joseph Marion, Anna McGlothlin, Eufrosina Young, Marianne Chase, Lindsay Pothier, Brittney Harkey, Hong Yu, Alex Sherman, Jeremy Shefner, Meghan Hall, Gale Kittle, Mariah R Connolly, James D Berry, Derek D'Agostino, Eric Tustison, Elisa Giacomelli, Erica Scirocco, Gustavo Alameda, Eduardo Locatelli, Doreen Ho, Adam Quick, Daragh Heitzman, Senda Ajroud-Driss, Stanley H Appel, Sheetal Shroff, Jonathan Katz, Kevin Felice, Nicholas J Maragakis, Zachary Simmons, Stephen A Goutman, Nicholas Olney, Timothy Miller, Joseph Americo Fernandes, Hristelina Ilieva, Omar Jawdat, Michael D Weiss, Laura Foster, Tuan Vu, Shafeeq Ladha, Margaret Ayo Owegi, Daniel S Newman, Ximena Arcila-Londono, Carlayne E Jackson, Andrea Swenson, Terry Heiman-Patterson, James Caress, Dominic Fee, Amanda Peltier, Richard Lewis, Jeffrey Rosenfeld, David Walk, Kristin Johnson, Matthew Elliott, Edward J Kasarskis, Seward Rutkove, Courtney E McIlduff, Richard Bedlack, Lauren Elman, Namita A Goyal, Kourosh Rezania, Paul Twydell, Michael Benatar, Jonathan Glass, Jeffrey A Cohen, Vovanti Jones, Lindsay Zilliox, James P Wymer, Said R Beydoun, Jaimin Shah, Gary L Pattee, Jennifer Martinez-Thompson, Shakti Nayar, Volkan Granit, Mary Donohue, Katheryn Grossman, Daniel J Campbell, Irfan A Qureshi, Merit E Cudkowicz, and Suma Babu
CNM-Au8 in Amyotrophic Lateral Sclerosis: The HEALEY ALS Platform Trial., Writing Committee for the HEALEY ALS Platform Trial, James D Berry, Nicholas J Maragakis, Eric A Macklin, Lori B Chibnik, Melanie Quintana, Benjamin R Saville, Michelle A Detry, Matteo Vestrucci, Joseph Marion, Anna McGlothlin, Elijah W Stommel, Marianne Chase, Lindsay Pothier, Brittney A Harkey, Hong Yu, Alex Sherman, Jeremy Shefner, Meghan Hall, Gale Kittle, Suma Babu, Jinsy Andrews, Derek D'Agostino, Eric Tustison, Erica Scirocco, Elisa Giacomelli, Gustavo Alameda, Eduardo Locatelli, Doreen Ho, Adam Quick, Senda Ajroud-Driss, Jonathan Katz, Daragh Heitzman, Stanley H Appel, Sheetal Shroff, Kevin J Felice, Zachary Simmons, Timothy Miller, Nicholas Olney, Michael D Weiss, Stephen A Goutman, Joseph Americo Fernandes, Omar Jawdat, Margaret Ayo Owegi, Laura Foster, Tuan Vu, Hristelina Ilieva, Daniel S Newman, Ximena Arcila-Londono, Carlayne Jackson, Shafeeq Ladha, Terry Heiman-Patterson, James Caress, Andrea Swenson, Amanda Peltier, Richard Lewis, Dominic Fee, Matthew Elliott, Richard Bedlack, Edward J Kasarskis, Lauren Elman, Jeffrey Rosenfeld, David Walk, Courtney E McIlduff, Paul Twydell, Eufrosina Young, Kristin Johnson, Kourosh Rezania, Namita A Goyal, Jeffrey A Cohen, Michael Benatar, Vovanti Jones, Jonathan Glass, Jaimin Shah, Said R Beydoun, James P Wymer, Lindsay Zilliox, Shakti Nayar, Gary L Pattee, Jennifer Martinez-Thompson, Austin Rynders, Jacob Evan, Jeremy Evan, Alan Hartford, Marjan Sepassi, Karen S Ho, Robert Glanzman, Benjamin Greenberg, Michael T Hotchkin, Sabrina Paganoni, Merit E Cudkowicz, and HEALEY ALS Platform Trial Study Group
Pridopidine in Amyotrophic Lateral Sclerosis: The HEALEY ALS Platform Trial., Writing Committee for the HEALEY ALS Platform Trial, Jeremy M Shefner, Björn Oskarsson, Eric A Macklin, Lori B Chibnik, Melanie Quintana, Benjamin R Saville, Michelle A Detry, Matteo Vestrucci, Joe Marion, Anna McGlothlin, Terry Heiman-Patterson, Marianne Chase, Lindsay Pothier, Brittney A Harkey, Hong Yu, Alexander V Sherman, Meghan Hall, Gale Kittle, James D Berry, Suma Babu, Jinsy Andrews, Derek D'Agostino, Eric Tustison, Erica Scirocco, Elisa Giacomelli, Gustavo Alameda, Eduardo Locatelli, Doreen Ho, Adam Quick, Senda Ajroud-Driss, Jonathan Katz, Daragh Heitzman, Stanley H Appel, Sheetal Shroff, Kevin Felice, Nicholas J Maragakis, Zachary Simmons, Timothy M Miller, Nicholas Olney, Michael D Weiss, Stephen A Goutman, Joseph Americo Fernandes, Omar Jawdat, Margaret Ayo Owegi, Laura A Foster, Tuan Vu, Hristelina Ilieva, Daniel S Newman, Ximena Arcila-Londono, Carlayne E Jackson, Shafeeq Ladha, James B Caress, Andrea Swenson, Amanda Peltier, Richard A Lewis, Dominic Fee, Matthew Elliott, Richard Bedlack, Edward J Kasarskis, Lauren Elman, Jeffrey Rosenfeld, David Walk, Courtney McIlduff, Paul Twydell, Eufrosina Young, Kristin Johnson, Kourosh Rezania, Namita A Goyal, Jeffrey A Cohen, Michael Benatar, Vovanti Jones, Jaimin Shah, Said R Beydoun, James P Wymer, Lindsay Zilliox, Shakti Nayar, Gary L Pattee, Jennifer Martinez-Thompson, Melanie L Leitner, Kelly Chen, Y Paul Goldberg, Yael Cohen, Michal Geva, Michael R Hayden, Sabrina Paganoni, Merit E Cudkowicz, and HEALEY ALS Platform Trial Study Group
Profiling a Multidisciplinary Team in Making a Change in Pharmaceutical Practice: Lessons Learned., Renee Rassilyer-Bomers, Diem Pham, Adam Corson, and Cara Gallegos
Discontinuation and Reinitiation of Dual-Labeled GLP-1 Receptor Agonists Among US Adults With Overweight or Obesity., Patricia J Rodriguez, Vincent Zhang, Samuel Gratzl, Duy Do, Brianna Goodwin Cartwright, Charlotte Baker, Ty J Gluckman, Nicholas Stucky, and Ezekiel J Emanuel
Pirtobrutinib monotherapy in Bruton tyrosine kinase inhibitor-intolerant patients with B-cell malignancies: results of the phase I/II BRUIN trial., Nirav N Shah, Michael Wang, Lindsey E Roeker, Krish Patel, Jennifer A Woyach, William G Wierda, Chaitra S Ujjani, Toby A Eyre, Pier Luigi Zinzani, Alvaro J Alencar, Paolo Ghia, Nicole Lamanna, Marc S Hoffmann, Manish R Patel, Ian Flinn, James N Gerson, Shuo Ma, Catherine C Coombs, Chan Y Cheah, Ewa Lech-Maranda, Bita Fakhri, Won Seog Kim, Minal A Barve, Jonathon B Cohen, Wojciech Jurczak, Talha Munir, Meghan C Thompson, Donald E Tsai, Katherine Bao, Nicholas A Cangemi, Jennifer F Kherani, Richard A Walgren, Hongmei Han, Amy S Ruppert, and Jennifer R Brown
Comparative effectiveness of GLP-1 receptor agonists on cardiovascular outcomes among adults with type 2 diabetes and moderate cardiovascular risk: emulation of a target trial., Stacey M Sklepinski, Yihong Deng, Kavya Sindu Swarna, Jeph Herrin, Eric C Polley, Joshua J Neumiller, Rodolfo J Galindo, Guillermo E Umpierrez, Joseph S Ross, Bijan J Borah, Bradley A Maron, Mindy M Mickelson, and Rozalina G McCoy
Pemigatinib for Previously Treated Metastatic or Unresectable Central Nervous System Tumors with FGFR Mutations or Rearrangements: FIGHT-207 Results., Iben Spanggaard, Marc Matrana, Caio Rocha Lima, Amit Mahipal, Maria Vieito, Alice Hervieu, Lipika Goyal, Jordi Rodón, Maria Luisa Veronese, Natalia Oliveira, Xin Li, Michael Schaffer, and Santosh Kesari
Glucagon-Like Peptide 1 Receptor Agonists and the Deepening Health Equity Divide in America., Kateri J Spinelli and Allison H Oakes
DRUG AND SINGLE-CELL GENE EXPRESSION INTEGRATION IDENTIFIES SENSITIVE AND RESISTANT GLIOBLASTOMA CELL POPULATIONS., Robert K Suter, Anna M Jermakowicz, Rithvik Veeramachaneni, Matthew D'Antuono, Longwei Zhang, Rishika Chowdary, Simon Kaeppeli, Madison Sharp, Pravallika Palwai, Vasileios Stathias, Grace Baker, Luz Ruiz, Winston Walters, Maria Cepero, Danielle Burgenske, Edward B Reilly, Anatol Oleksijew, Mark G Anderson, Sion Ll Williams, Michael E Ivan, Ricardo J Komotar, Macarena I De La Fuente, Gregory Stein, Alexander Wojcinski, Santosh Kesari, Jann N Sarkaria, Stephan C Schürer, and Nagi G Ayad
Abemaciclib in combination with therapies for patients with metastatic breast cancer: a phase 1b study., Sara M Tolaney, Komal Jhaveri, Teresa Helsten, Shannon L Puhalla, Alison Conlin, E Claire Dees, Muralidhar Beeram, Sonya C Chapman, Andrew Lithio, Lacey M Litchfield, and Matthew P Goetz
A Real-World Cohort Study of the Risks of Kidney Failure and Death in Diabetes., Katherine Tuttle, Lindsey M Kornowske, Cami R Jones, Christina L Reynolds, Radica Alicic, Kenn Daratha, Joshua J Neumiller, O Kenrik Duru, Susanne B Nicholas, Keith C Norris, and Meda E Pavkov
Molecular Correlates of Long-Term Response to Bevacizumab in Glioblastoma., John L Villano, Catherine R Garcia, Rachael M Morgan, Shulin Zhang, Jill Kolesar, Farhan A Mirza, Timothy Samec, Joanne Xiu, Stephanie Rock, Santosh Kesari, Emil Lou, Sonikpreet Aulakh, Michael J Glantz, and Eric T Wong
Submissions from 2024
Neoadjuvant Trebananib plus Paclitaxel-based Chemotherapy for Stage II/III Breast Cancer in the Adaptively Randomized I-SPY2 Trial-Efficacy and Biomarker Discovery., Kathy S Albain, Christina Yau, Emanuel F Petricoin, Denise M Wolf, Julie E Lang, A Jo Chien, Tufia Haddad, Andres Forero-Torres, Anne M Wallace, Henry G Kaplan, Lajos Pusztai, David Euhus, Rita Nanda, Anthony D Elias, Amy S Clark, Constantine Godellas, Judy C Boughey, Claudine Isaacs, Debu Tripathy, Janice Lu, Rachel L Yung, Rosa I Gallagher, Julia D Wulfkuhle, Lamorna Brown-Swigart, Gregor Krings, Yunn Yi Chen, David A Potter, Erica Stringer-Reasor, Sarah Blair, Smita M Asare, Amy Wilson, Gillian L Hirst, Ruby Singhrao, Meredith Buxton, Julia L Clennell, Ashish Sanil, Scott Berry, Adam L Asare, Jeffrey B Matthews, Angela M DeMichele, Nola M Hylton, Michelle Melisko, Jane Perlmutter, Hope S Rugo, W Fraser Symmans, Laura J Van't Veer, Douglas Yee, Donald A Berry, and Laura J Esserman
Early recapture of response with tofacitinib 10 mg twice daily in patients with ulcerative colitis in OCTAVE Open following dose reduction or treatment interruption in OCTAVE Sustain., Jessica R Allegretti, Krisztina B Gecse, Michael Chiorean, Marjorie Argollo, Xiang Guo, Nervin Lawendy, Chinyu Su, Rajiv Mundayat, Jerome Paulissen, Leonardo Salese, and Peter M Irving
Drug delivery in leptomeningeal disease: Navigating barriers and beyond., Numair Arshad, Nupur Biswas, Jaya Gill, Santosh Kesari, and Shashaanka Ashili
Pomalidomide/Daratumumab/Dexamethasone in Relapsed or Refractory Multiple Myeloma: Final Overall Survival From MM-014., Nizar J Bahlis, Christy Samaras, Donna Reece, Michael Sebag, Jeffrey Matous, Jesús G Berdeja, Jesse Shustik, Gary J Schiller, Siddhartha Ganguly, Kevin Song, Christopher S Seet, Mirelis Acosta-Rivera, Michael Bar, Donald Quick, Gustavo Fonseca, Hongjuan Liu, Christian Gentili, Pavit Singh, and David Siegel
Safety and real-world dosing of onabotulinumtoxinA for the treatment of adult spasticity: post hoc analysis of the Adult Spasticity International Registry study., Ganesh Bavikatte, Alberto Esquenazi, Michael A Dimyan, Khashayar Dashtipour, Wuwei Feng, Angeli Mayadev, Kristina Fanning, Tiziana Musacchio, Aleksej Zuzek, and Gerard E Francisco
Safety and efficacy of arimoclomol in patients with early amyotrophic lateral sclerosis (ORARIALS-01): a randomised, double-blind, placebo-controlled, multicentre, phase 3 trial., Michael Benatar, Thomas Hansen, Dror Rom, Marie A Geist, Thomas Blaettler, William Camu, Magdalena Kuzma-Kozakiewicz, Leonard H van den Berg, Raul Juntas Morales, Adriano Chio, Peter M Andersen, Pierre-Francois Pradat, Dale Lange, Philip Van Damme, Gabriele Mora, Mariusz Grudniak, Matthew Elliott, Susanne Petri, Nicholas T Olney, Shafeeq Ladha, Namita A Goyal, Thomas Meyer, Michael G Hanna, Colin Quinn, Angela Genge, Lorne Zinman, Duaa Jabari, Christen Shoesmith, Albert C Ludolph, Christoph Neuwirth, Sharon Nations, Jeremy M Shefner, Martin R Turner, Joanne Wuu, Richard Bennett, Hoang Dang, and Claus Sundgreen
Aldosterone synthase inhibitor (BI 690517) therapy for people with diabetes and albuminuric chronic kidney disease: A multicentre, randomized, double-blind, placebo-controlled, Phase I trial., Stefan R Bornstein, Dick de Zeeuw, Hiddo J L Heerspink, Friedrich Schulze, Lisa Cronin, Arne Wenz, Katherine Tuttle, Samy Hadjadj, and Peter Rossing
An inconspicuous identification: Isolation and identification of a novel Pichia species presenting as fungemia following cardiac surgery., Allorie T Caldwell, Toni Gabaldón, Verónica Mixão, Nancy L Wengenack, Benjamin P Westley, and Ryan W Stevens
Safety and Efficacy of Empiric De-escalation of Antibiotics for Pneumonia in the Intensive Care Unit, Brandon Carron
Optimizing tacrolimus dosing in Hispanic renal transplant patients: insights from real-world data., Athanasios Chamzas, Eglis Tellez, Andrew SyBing, Jogarao V S Gobburu, and Mathangi Gopalakrishnan
Efficacy and safety of macitentan in Fontan-palliated patients: 52-week randomized, placebo-controlled RUBATO Phase 3 trial and open-label extension., Paul Clift, Felix Berger, Lars Sondergaard, Petra Antonova, Patrick Disney, Jeremy Nicolarsen, Jean-Benoît Thambo, Lidia Tomkiewicz Pajak, Jou-Kou Wang, Annette Schophuus Jensen, Michela Efficace, Michael Friberg, Diana Haberle, Verena Walter, and Yves d'Udekem
Continuous improvement through differential trajectories of individual minimal disease activity criteria with guselkumab in active psoriatic arthritis: post hoc analysis of a phase 3, randomized, double-blind, placebo-controlled study., Laura C Coates, Proton Rahman, Philip J Mease, May Shawi, Emmanouil Rampakakis, Alexa P Kollmeier, Xie L Xu, Soumya D Chakravarty, Iain B McInnes, and Lai-Shan Tam
A secukinumab dose-escalation study in patients with ankylosing spondylitis not achieving inactive disease after 16 weeks of treatment., Atul Deodhar, Alan J Kivitz, Marina Magrey, Jessica A Walsh, Philip J Mease, Maria Greenwald, Farid Kianifard, Chelsea Elam, Gopi M Bommidi, Adam Winseck, and Lianne S Gensler
Exploring the Effects of Ixekizumab on Pain in Patients with Ankylosing Spondylitis Based on Objective Measures of Inflammation: Post Hoc Analysis from a Large Randomized Clinical Trial., Kurt de Vlam, Walter P Maksymowych, Gaia Gallo, Proton Rahman, Philip Mease, Venkatesh Krishnan, Conor J McVeigh, Jeffrey Lisse, Danting Zhu, Rebecca J Bolce, and Philip G Conaghan
Naloxone: From Legislation to Distribution, Kailyn Elliot, Emily Stewart, and John Delfeld
Phase 2 Trial of Deucravacitinib in Psoriatic Arthritis: Biomarkers Associated With Disease Activity, Pharmacodynamics, and Clinical Responses., Oliver FitzGerald, Dafna D Gladman, Philip Mease, Christopher Ritchlin, Josef S Smolen, Lu Gao, Yanhua Hu, Miroslawa Nowak, Subhashis Banerjee, and Ian Catlett
SYNCHRONIZE: Real-World Retrospective Safety Analysis of Patients Treated with OnabotulinumtoxinA for More than One Therapeutic Indication., Grace Forde, Benjamin M Brucker, Kimberly Becker Ifantides, Atul T Patel, A Mayadev, Theodore Brown, Ziyad Ayyoub, Kenneth Martinez, Ritu Singh, Mariana Nelson, Simona Battucci, Irina Yushmanova, Ahunna Ukah, and Christopher Rhyne
Left atrial appendage occlusion needs lifetime management not lifetime medications., Sameer Gafoor and Sidakpal S Panaich
Results from a benzodiazepine-minimizing protocol for inpatient management of alcohol withdrawal., Jennifer Gaston, Emily J Cox, Hsin-Fang Li, Caitlin Klamper, and John F Wurzel
Efficacy and safety of tofacitinib in an open-label, long-term extension study in patients with psoriatic arthritis who received adalimumab or tofacitinib in a Phase 3 randomized controlled study: a post hoc analysis., Dafna D Gladman, Peter Nash, Philip J Mease, Oliver FitzGerald, Stephanie Duench, Mary Jane Cadatal, and Karim R Masri
Design and baseline characteristics of the Finerenone, in addition to standard of care, on the progression of kidney disease in patients with Non-Diabetic Chronic Kidney Disease (FIND-CKD) randomized trial., Hiddo J L Heerspink, Rajiv Agarwal, George L Bakris, David Z I Cherney, Carolyn S P Lam, Brendon L Neuen, Pantelis A Sarafidis, Katherine Tuttle, Christoph Wanner, Meike D Brinker, Sara Dizayee, Peter Kolkhof, Patrick Schloemer, Paula Vesterinen, and Vlado Perkovic
Bimekizumab provided rapid improvements in patient-reported symptoms and health-related quality of life in patients with active psoriatic arthritis: pooled 16-week results from two phase 3 studies., M Elaine Husni, Philip Mease, Joseph F Merola, William Tillett, Nadine Goldammer, Barbara Ink, Jason Coarse, Jérémy Lambert, Vanessa Taieb, and Dafna D Gladman
Accelerating adverse pregnancy outcomes research amidst rising medication use: parallel retrospective cohort analyses for signal prioritization., Yeon Mi Hwang, Samantha N Piekos, Alison G Paquette, Qi Wei, Nathan D Price, Leroy Hood, and Jennifer J Hadlock
Timing of selective serotonin reuptake inhibitor use and risk for preterm birth and related adverse events: with a consideration of the COVID-19 pandemic period., Yeon Mi Hwang, Ryan T Roper, Samantha N Piekos, Daniel A Enquobahrie, Mary F Hebert, Alison G Paquette, Priyanka Baloni, Nathan D Price, Leroy Hood, and Jennifer J Hadlock
A phase I dose-escalation study of pulsatile afatinib in patients with recurrent or progressive brain cancer., Tiffany Juarez, Jaya Mini Gill, Annie Heng, Jose Carrillo, Naveed Wagle, Natsuko Nomura, Minhdan Nguyen, Judy D Truong, Lucia Dobrawa, Walavan Sivakumar, Garni Barkhoudarian, Daniel F Kelly, and Santosh Kesari
Deucravacitinib, a selective, TYK2 inhibitor, in psoriatic arthritis: Achievement of minimal disease activity components in a phase 2 trial., Arthur Kavanaugh, Laura C Coates, Philip Mease, Miroslawa Nowak, Lauren Hippeli, Thomas Lehman, Subhashis Banerjee, and Joseph F Merola
Pre-radiation Nivolumab plus ipilimumab in patients with newly diagnosed high-grade gliomas., Santosh Kesari, Alexandre Wojcinski, Sarabjot Pabla, R J Seager, Jaya Mini Gill, Jose Carrillo, Naveed Wagle, David J. Park, Minhdan Nguyen, Judy D Truong, Yuki Takasumi, Lisa Chaiken, Shu-Ching Chang, Garni Barkhoudarian, Daniel F Kelly, and Tiffany Juarez
Kinetic Trajectories of Glucose Uptake in Single Cancer Cells Reveal a Drug-Induced Cell-State Change Within Hours of Drug Treatment., Jungwoo Kim, Rachel H Ng, JingXin Liang, Dazy Johnson, Young Shik Shin, Arion F Chatziioannou, Michael E Phelps, Wei Wei, Raphael D Levine, and James R Heath
Association of achieving clinical disease control criteria and patient-reported outcomes in bimekizumab-treated patients with active psoriatic arthritis: results from two phase III studies., Lars Erik Kristensen, William Tillett, Peter Nash, Laura C Coates, Philip Mease, Alexis Ogdie, Paolo Gisondi, Barbara Ink, Adam R Prickett, Rajan Bajracharya, Vanessa Taieb, Nikos Lyris, Jérémy Lambert, and Jessica A Walsh
Toxin-Induced Liver Injury and Extracorporeal Treatment of Liver Failure., Angela H Lam and Joshua D King
Trastuzumab deruxtecan in patients with solid tumours harbouring specific activating HER2 mutations (DESTINY-PanTumor01): an international, phase 2 study., Bob T Li, Funda Meric-Bernstam, Aditya Bardia, Yoichi Naito, Salvatore Siena, Philippe Aftimos, Ian Churchill Anderson, Giuseppe Curigliano, Maria de Miguel, Maitri Kalra, Do-Youn Oh, Joon Oh Park, Sophie Postel-Vinay, Sun Young Rha, Taroh Satoh, Iben Spanggaard, Flavia Michelini, Ann Smith, Karime Kalil Machado, Cristina Saura, and DESTINY-PanTumor01 study group
Cardiovascular outcomes with semaglutide by severity of chronic kidney disease in type 2 diabetes: the FLOW trial., Kenneth W Mahaffey, Katherine Tuttle, Mustafa Arici, Florian M M Baeres, George Bakris, David M Charytan, David Z I Cherney, Gil Chernin, Ricardo Correa-Rotter, Janusz Gumprecht, Thomas Idorn, Giuseppe Pugliese, Ida Kirstine Bull Rasmussen, Søren Rasmussen, Peter Rossing, Ekaterina Sokareva, Johannes F E Mann, Vlado Perkovic, and Richard Pratley
Effects of semaglutide with and without concomitant SGLT2 inhibitor use in participants with type 2 diabetes and chronic kidney disease in the FLOW trial., Johannes F E Mann, Peter Rossing, George Bakris, Nicolas Belmar, Heidrun Bosch-Traberg, Robert Busch, David M Charytan, Samy Hadjadj, Pieter Gillard, José Luis Górriz, Thomas Idorn, Linong Ji, Kenneth W Mahaffey, Vlado Perkovic, Søren Rasmussen, Roland E Schmieder, Richard E Pratley, and Katherine Tuttle
Real-World Safety and Effectiveness of Dimethyl Fumarate in Patients with MS: Results from the ESTEEM Phase 4 and PROCLAIM Phase 3 Studies with a Focus on Older Patients., Yang Mao-Draayer, Amit Bar-Or, Konstantin Balashov, John Foley, Kyle E Smoot, Erin E Longbrake, Derrick Robertson, Jason P Mendoza, James B Lewin, Nicholas Everage, Ivan Božin, Jennifer Lyons, Oksana Mokliatchouk, Eris Bame, and Fabrizio Giuliani
Frailty, multimorbidity and polypharmacy: exploratory analyses of the effects of empagliflozin from the EMPA-KIDNEY trial., Kaitlin J Mayne, Rebecca J Sardell, Natalie Staplin, Parminder K Judge, Doreen Zhu, Emily Sammons, David Zi Cherney, Alfred K Cheung, Aldo P Maggioni, Masaomi Nangaku, Xavier Rossello, Katherine Tuttle, Katsuhito Ihara, Tomoko Iwata, Christoph Wanner, Jonathan Emberson, David Preiss, Martin J Landray, Colin Baigent FMedSci, Richard Haynes, and William G Herrington
Effectiveness of glucose-lowering medications on cardiovascular outcomes in patients with type 2 diabetes at moderate cardiovascular risk., Rozalina G McCoy, Jeph Herrin, Kavya Sindhu Swarna, Yihong Deng, David M Kent, Joseph S Ross, Guillermo E Umpierrez, Rodolfo J Galindo, William H Crown, Bijan J Borah, Victor M Montori, Juan P Brito, Joshua J Neumiller, Mindy M Mickelson, and Eric C Polley
Efficacy and Safety of Bimekizumab in Patients With Psoriatic Arthritis With or Without Methotrexate: 52-Week Results From Two Phase 3 Studies., Iain B McInnes, Philip Mease, Yoshiya Tanaka, Laure Gossec, M Elaine Husni, Lars Erik Kristensen, Richard B Warren, Barbara Ink, Rajan Bajracharya, Jason Coarse, and Alice B Gottlieb
Comparative efficacy and safety of bimekizumab in psoriatic arthritis: a systematic literature review and network meta-analysis., Philip Mease, Dafna D Gladman, Joseph F Merola, Peter Nash, Stacy Grieve, Victor Laliman-Khara, Damon Willems, Vanessa Taieb, Adam R Prickett, and Laura C Coates
Safety and Efficacy of Bimekizumab in Patients with Psoriatic Arthritis: 2-Year Results from Two Phase 3 Studies., Philip J Mease, Joseph F Merola, Yoshiya Tanaka, Laure Gossec, Iain B McInnes, Christopher T Ritchlin, Robert B M Landewé, Akihiko Asahina, Barbara Ink, Andrea Heinrichs, Rajan Bajracharya, Vishvesh Shende, Jason Coarse, and Laura C Coates
Comparative Effectiveness of Bimekizumab and Ustekinumab in Patients with Psoriatic Arthritis at 52 Weeks Assessed Using a Matching-Adjusted Indirect Comparison., Philip J Mease, Richard B Warren, Peter Nash, Jean-Marie Grouin, Nikos Lyris, Vanessa Taieb, Jason Eells, and Iain B McInnes
Comparative Effectiveness of Bimekizumab and Risankizumab in Patients with Psoriatic Arthritis at 52 Weeks Assessed Using a Matching-Adjusted Indirect Comparison., Philip J Mease, Richard B Warren, Peter Nash, Jean-Marie Grouin, Nikos Lyris, Damon Willems, Vanessa Taieb, Jason Eells, and Iain B McInnes
Improvements in Patient-Reported Outcomes Through Six Months of Guselkumab Treatment in Patients With Active Psoriatic Arthritis: Real-World Data From the CorEvitas Psoriatic Arthritis/Spondyloarthritis Registry., Philip Mease, Alexis Ogdie, John Tesser, Natalie J Shiff, Ruizhi Sophia Zhao, Soumya D Chakravarty, Michael Kelleman, Rhiannon Dodge, Robert R McLean, Aaron Broadwell, Arthur Kavanaugh, and Joseph F Merola
Impact of intra-tumoral immunity on predicting response and survival after neoadjuvant cisplatin-based chemotherapy in patients with muscle invasive bladder cancer., Alberto Mendoza-Valderrey, Jane Choe, Daria Kessler, Gianna Jimenez, Xinmin Li, Steven E Kolker, Warren M Allen, Jennifer M Linehan, Przemyslaw W Twardowski, and Maria Ascierto
The intersection of frailty and metabolism., Manish Mishra, Judy Wu, Alice E Kane, and Susan E Howlett
Sodium-glucose cotransporter 2 inhibitors and cardiovascular events among patients with type 2 diabetes and low-to-normal body mass index: a nationwide cohort study., Yuichiro Mori, Toshiaki Komura, Motohiko Adomi, Ryuichiro Yagi, Shingo Fukuma, Naoki Kondo, Motoko Yanagita, O Kenrik Duru, Katherine Tuttle, and Kosuke Inoue
Improved Pain, Morning Stiffness, and Fatigue With Bimekizumab in Axial Spondyloarthritis: Results From the Phase III BE MOBILE Studies., Victoria Navarro-Compán, Martin Rudwaleit, Maureen Dubreuil, Marina Magrey, Helena Marzo-Ortega, Philip Mease, Jessica A Walsh, Maxime Dougados, Christine de la Loge, Carmen Fleurinck, Ute Massow, Thomas Vaux, Vanessa Taieb, and Atul Deodhar
Insulin Icodec., Matthew Nelson
Cardiovascular, Kidney and Safety Outcomes with GLP-1 Receptor Agonists Alone and in Combination with SGLT2 Inhibitors in Type 2 Diabetes: A Systematic Review and Meta-Analysis., Brendon L Neuen, Robert A Fletcher, Lauren Heath, Adam Perkovic, Muthiah Vaduganathan, Sunil Badve, Katherine Tuttle, Richard Pratley, Hertzel C Gerstein, Vlado Perkovic, and Hiddo J L Heerspink
Permanent Pacing Reduces Blood Pressure in Older Patients with Drug-resistant Hypertension: A New Pacing Paradigm?, Bich Lien Nguyen, Michael H Burnam, Francesco Accardo, Angela Angione, Roberto Scacciavillani, Carly Pierson, and Eli S Gang
Real world experience with sodium phenylbutyrate-taurursodiol for ALS: Lessons learned from a failed drug., Nicholas T Olney and Michael D Weiss
Med rec double check: Inpatient psychiatry medication errors identified on admission using Medicaid Web portals and electronic pharmaceutical claims data., Su Su E Oo and Ian R McGrane
7P Patient-relevant endpoints from PAPILLON: Amivantamab plus chemotherapy vs chemotherapy as first-line treatment of EGFR exon 20 insertion-mutated (Ex20ins) advanced NSCLC, L Paz-Ares, Rachel E Sanborn, and See full list of authors in comments
Semaglutide for Chronic Kidney Disease in Type 2 Diabetes. Reply., Vlado Perkovic, Katherine Tuttle, and Richard Pratley
Safety and tolerability of tegoprubart in patients with amyotrophic lateral sclerosis: A Phase 2A clinical trial., Steven Perrin, Shafeeq Ladha, Nicholas Maragakis, Michael H Rivner, Jonathan Katz, Angela Genge, Nicholas T Olney, Dale Lange, Daragh Heitzman, Cynthia Bodkin, Omar Jawdat, Namita A Goyal, Jeffrey D Bornstein, Carmen Mak, Stanley H Appel, and Sabrina Paganoni
