Our expanded team of specialists – many of whom completed fellowships and residencies at prestigious academic centers – offers comprehensive services for treating any condition of the brain, spine and nervous system. With nearly 50 subspecialties represented, we offer complex and minimally invasive surgery as well as ongoing care for pituitary and skull base tumors, stroke, peripheral nerve disease, multiple sclerosis, Parkinson’s disease, Alzheimer’s disease, ALS, epilepsy and more.

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Submissions from 2023

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Comprehensive Venous Outflow Predicts Functional Outcomes in Patients with Acute Ischemic Stroke Treated by Thrombectomy., G Adusumilli, T D Faizy, S Christensen, M Mlynash, Yince Loh, G W Albers, M G Lansberg, J Fiehler, and J J Heit

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Anti-CD20 monoclonal antibody therapy in postpartum women with neurological conditions., Annika Anderson, William Rowles, Shane Poole, Ayushi Balan, Carolyn Bevan, Rachel Brandstadter, Andrea I Ciplea, Joanna Cooper, Michelle Fabian, Thomas W Hale, Dina Jacobs, Mihir Kakara, Kristen M Krysko, Erin E Longbrake, Jacqueline Marcus, Pavle Repovic, Claire S Riley, Andrew R Romeo, Alice Rutatangwa, Timothy West, Kerstin Hellwig, Sara C LaHue, and Riley Bove

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Would you do it again? Discrepancies between patient and surgeon perceptions following adult spine deformity surgery., Shay Bess, Breton Line, Christopher Ames, Douglas Burton, Gregory Mundis, Robert Eastlack, Robert A Hart, Munish Gupta, Eric Klineberg, Han Jo Kim, Richard Hostin, Khaled Kebaish, Virgine Lafage, Renaud Lafage, Frank Schwab, Christopher Shaffrey, and Justin S Smith

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Postoperative Discharge to Acute Rehabilitation or Skilled Nursing Facility Compared to Home Does Not Reduce Hospital Readmissions, Return to Surgery or Improve Outcomes Following Adult Spine Deformity Surgery., Shay Bess, Breton G Line, Pierce Nunley, Christopher Ames, Douglas Burton, Gregory Mundis, Robert Eastlack, Robert A Hart, Munish Gupta, Eric Klineberg, Han Jo Kim, Michael Kelly, Richard Hostin, Khaled Kebaish, Virgine Lafage, Renaud Lafage, Frank Schwab, Christopher Shaffrey, Justin S Smith, and International Spine Study Group

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Impact of Eating a Carbohydrate-Restricted Diet on Cortical Atrophy in a Cross-Section of Amyloid Positive Patients with Alzheimer's Disease: A Small Sample Study., Jennifer Bramen, Prabha Siddarth, Emily S Popa, Gavin T Kress, Molly Rapozo, John F Hodes, Aarthi Ganapathi, Colby B Slyapich, Ryan M. Glatt, Kyron P Pierce, Verna R Porter, Claudia L Wong, Mihae Kim, Richelin V Dye, Stella Panos, Tess Bookheimer, Tori Togashi, Spencer Loong, Cyrus A Raji, Susan Y Bookheimer, Jared C Roach, and David A Merrill

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Non-Invasive Transcutaneous Afferent Patterned Stimulation Therapy Offers Action Tremor Relief in Parkinson's Disease., Salima Brillman, Pravin Khemani, Stuart H Isaacson, Rajesh Pahwa, Ruta Deshpande, Vivien Zraick, Apoorva Rajagopal, Dhira Khosla, and Kathryn H Rosenbluth

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The aging brain: risk factors and interventions for long term brain health in women., Jessica Z K Caldwell and Nancy B. Isenberg

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High-dose vitamin D3 supplementation in relapsing-remitting multiple sclerosis: a randomised clinical trial, Sandra D Cassard, Kathryn C Fitzgerald, Peiqing Qian, Susan A Emrich, Christina J Azevedo, Andrew D Goodman, Elizabeth A Sugar, Daniel Pelletier, Emmanuelle Waubant, and Ellen M Mowry

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Longitudinal Changes in Cognitive Test Scores in Patients With Relapsing Remitting Multiple Sclerosis: An Analysis of the DECIDE Dataset., Nina Castrogiovanni, Jop Mostert, Pavle Repovic, James D Bowen, Bernard M J Uitdehaag, Eva M M Strijbis, Gary R Cutter, and Marcus W Koch

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Binned Data Provide Better Imputation of Missing Time Series Data from Wearables., Shweta Chakrabarti, Nupur Biswas, Khushi Karnani, Vijay Padul, Lawrence D Jones, Santosh Kesari, and Shashaanka Ashili

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Sexual and Gender Diversity in Pediatric Neurology: Why We Care., Alison Christy, Jaclyn Martindale, Jennifer Hranilovich, Casey Orozco-Poore, Finley Kernan-Schloss, Chase T M Anderson, Jonathan Strober, Wendy Mitchell, and Mackenzie P Lerario

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Clinician-Performed Thyroid Fine Needle Aspiration With On-Site Review Improves Diagnostic Yield., Isabelle Chu, Oliver Bellevue, Joseph C Sniezek, and Nuria Perez-Reyes

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Stand by Me: Using an Enhanced Recovery After Surgery (ERAS) Checklist to Guide Early Mobility of Postoperative Craniotomy Patients on a Progressive Care Unit, Jerome Codilla, Alyssa Mooney, Joanna Arraiza, Sohl Chapman, Nkiru Chukwudi, and Ronald Rosales

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Vertebral-Venous fistulas: Single center experience and practical treatment approach., Matias Costa, Mohammed Basamh, Juan Vivanco-Suarez, Daniel Casanova, Matias Baldoncini, Abdullah Alobaid, Yince Loh, Akshal Patel, Cameron G McDougall, and Stephen J Monteith

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Longitudinal Assessment of Modern Spine Surgery Training: 10-Year Follow-up of a Nationwide Survey of Residency and Spine Fellowship Program Directors., Alan H Daniels, Daniel Alsoof, Christopher L McDonald, Andrew S Zhang, Bassel G Diebo, Craig P Eberson, Eren O Kuris, William Lavelle, Christopher P Ames, Christopher I Shaffrey, and Robert A Hart

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Capicua (CIC) mutations in gliomas in association with MAPK activation for exposing a potential therapeutic target., Sourat Darabi, Joanne Xiu, Timothy Samec, Santosh Kesari, Jose Carrillo, Sonikpreet Aulakh, Kyle M Walsh, Soma Sengupta, Ashley Sumrall, David Spetzler, Michael Glantz, and Michael J Demeure

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Hemodynamic Management in the Prevention and Treatment of Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage., Steven Deem, Michael Diringer, Sarah Livesay, and Miriam M Treggiari

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Response to "Treating Vasospasm with IV Milrinone: RELAX (the Vessel) or DON'T DO IT!"., Steven Deem, Sarah Livesay, and Miriam M Treggiari

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Practical considerations when providing palliative care to patients with neuroendocrine tumors in the context of routine disease management or hospice care., Jaydira Del Rivero, Josh Mailman, Michael W Rabow, Jennifer A Chan, Sarah Creed, Hagen F Kennecke, Janice Pasieka, Jennifer Zuar, Simron Singh, and Lauren Fishbein

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Height Gain Following Correction of Adult Spinal Deformity., Bassel G Diebo, Zachary L Tataryn, Daniel Alsoof, Renaud Lafage, Robert A Hart, Peter G Passias, Christopher P Ames, Justin K Scheer, Stephen J Lewis, Christopher I Shaffrey, Douglas C Burton, Vedat Deviren, Breton G Line, Alex Soroceanu, D Kojo Hamilton, Eric O Klineberg, Gregory M Mundis, Han Jo Kim, Jeffrey L Gum, Justin S Smith, Juan S Uribe, Michael P Kelly, Khaled M Kebaish, Munish C Gupta, Pierce D Nunley, Robert K Eastlack, Richard Hostin, Themistocles S Protopsaltis, Lawrence G Lenke, Frank J Schwab, Shay Bess, Virginie Lafage, and Alan H Daniels

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Immunotherapy for brain metastases and primary brain tumors., Anna M Di Giacomo, Maximilian J Mair, Michele Ceccarelli, Andrea Anichini, Ramy Ibrahim, Michael Weller, Michael Lahn, Alexander M M Eggermont, Bernard Fox, and Michele Maio

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Impact of Race/Ethnicity on Hospital Resource Utilization After Elective Anterior Cervical Decompression and Fusion for Degenerative Myelopathy., Jerry Y Du, Collin W Blackburn, Jens R Chapman, Nicholas U Ahn, and Randall E Marcus

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Effects of baseline age and disease duration on the efficacy and safety of siponimod in patients with active SPMS: Post hoc analyses from the EXPAND study., Le H Hua, Amit Bar-Or, Stanley L Cohan, Fred D Lublin, Patricia K Coyle, Bruce Ac Cree, Xiangyi Meng, Wendy Su, Gina Mavrikis Cox, and Robert J Fox

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Seizures Following Self-Medication With Colloidal Silver: A Case Report., Daniel Hu and Cary Yuen

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The Vicious Cycle of Melanoma-Microglia Crosstalk: Inter-Melanoma Variations in the Brain-Metastasis-Promoting IL-6/JAK/STAT3 Signaling Pathway., Sivan Izraely, Shlomit Ben-Menachem, Sapir Malka, Orit Sagi-Assif, Matias A Bustos, Orit Adir, Tsipi Meshel, Maharrish Chelladurai, Suyeon Ryu, Romela Irene Ramos, Metsada Pasmanik-Chor, Dave S B Hoon, and Isaac P Witz

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SMARTfit Dual-Task Exercise Improves Cognition and Physical Function in Older Adults With Mild Cognitive Impairment: Results of a Community-Based Pilot Study., Sameer Jhaveri, Matthew Romanyk, Ryan Glatt, and Nikhil Satchidanand

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Differences in concussion knowledge between parents and their children in a multidisciplinary concussion clinic sample., Abigail Johnson, Marie Van Tubbergen, Andrew Hashikawa, Ingrid Ichesco, Andrea Almeida, Kristen Kolberg, and Jennifer Larson

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Brain volume, energy balance, and cardiovascular health in two nonindustrial South American populations., Hillard Kaplan, Paul L Hooper, Margaret Gatz, Wendy J Mack, E Meng Law, Helena C Chui, M Linda Sutherland, James D Sutherland, Christopher J Rowan, L Samuel Wann, Adel H Allam, Randall C Thompson, David E Michalik, Guido Lombardi, Michael Miyamoto, Daniel Eid Rodriguez, Juan Copajira Adrian, Raul Quispe Gutierrez, Bret A Beheim, Daniel K Cummings, Edmond Seabright, Sarah Alami, Angela R Garcia, Kenneth Buetow, Gregory S Thomas, Caleb E Finch, Jonathan Stieglitz, Benjamin C Trumble, Michael D Gurven, and Andrei Irimia

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Patient Perception of Education, Care Coordination, and Psychological Distress After Developing Facial Paralysis: A Qualitative Study., Natalie R Kenton, Merai Estafanous, Kyohei Itamura, Ania Filus, Shanthi Gowrinathan, Neil A Martin, Walavan Sivakumar, Garni Barkhoudarian, Patrick J Byrne, and Amit Kochhar

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Response to OKN-007 and NAC in a Patient with Unilateral Hearing Loss and Chronic Tinnitus from Vestibular Schwannoma, Santosh Kesari, Andy Liu, Jaya Mini Gill, Minhdan Nguyen, Judy D Truong, Raffi Nersesian, Emma Chacon, Akanksha Sharma, Naveed Wagle, Chester Griffiths, Gregory Frazer, Max Zats, Shinwook Kang, Matthew B. West, Richard D. Kopke, and Tiffany Juarez

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Target cell-specific synaptic dynamics of excitatory to inhibitory neuron connections in supragranular layers of human neocortex., Mean-Hwan Kim, Cristina Radaelli, Elliot R Thomsen, Deja Monet, Thomas Chartrand, Nikolas L Jorstad, Joseph T Mahoney, Michael J Taormina, Brian Long, Katherine Baker, Trygve E Bakken, Luke Campagnola, Tamara Casper, Michael Clark, Nick Dee, Florence D'Orazi, Clare Gamlin, Brian E Kalmbach, Sara Kebede, Brian R Lee, Lindsay Ng, Jessica Trinh, Charles Cobbs, Ryder P Gwinn, C Dirk Keene, Andrew L Ko, Jeffrey G Ojemann, Daniel L Silbergeld, Staci A Sorensen, Jim Berg, Kimberly A Smith, Philip R Nicovich, Tim Jarsky, Hongkui Zeng, Jonathan T Ting, Boaz P Levi, and Ed Lein

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Threshold definitions for significant change on the timed 25-foot walk and nine-hole peg test in primary progressive multiple sclerosis., Marcus W Koch, Pavle Repovic, Jop Mostert, James D Bowen, Jacynthe Comtois, Eva Strijbis, Bernard Uitdehaag, and Gary Cutter

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Structural analysis of human G-protein-coupled receptor 17 ligand binding sites., Saravanan Konda Mani, Ramesh Thiyagarajan, Olli Yli-Harja, Meenakshisundaram Kandhavelu, and Akshaya Murugesan

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Preliminary validation of a structural magnetic resonance imaging metric for tracking dementia-related neurodegeneration and future decline., Gavin T Kress, Emily S Popa, Paul M Thompson, Susan Y Bookheimer, Sophia I Thomopoulos, Christopher R K Ching, Hong Zheng, Daniel A Hirsh, David A Merrill, Stella Panos, Cyrus A Raji, Prabha Siddarth, and Jennifer E Bramen

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Trial of Globus Pallidus Focused Ultrasound Ablation in Parkinson's Disease., Vibhor Krishna, Paul S Fishman, Howard M Eisenberg, Michael Kaplitt, Gordon Baltuch, Jin Woo Chang, Wei-Chieh Chang, Raul Martinez Fernandez, Marta Del Alamo, Casey H Halpern, Pejman Ghanouni, Roberto Eleopra, Rees Cosgrove, Jorge Guridi, Ryder Gwinn, Pravin Khemani, Andres M Lozano, Nathan McDannold, Alfonso Fasano, Marius Constantinescu, Ilana Schlesinger, Arif Dalvi, and W Jeff Elias

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No Delayed Ruptures on Long-Term Follow-Up of a Case Series of Persistently Filling Saccular Internal Carotid Artery Aneurysms After Flow Diversion With the Pipeline Embolization Device., Ryan P Lee, Meghana Bhimreddy, Jennifer Kim, Robert T Wicks, Risheng Xu, Matthew Bender, Wuyang Yang, Shahab Aldin Sattari, Alice Hung, Christopher M Jackson, L Fernando Gonzalez, Judy Huang, Rafael Tamargo, Cameron G McDougall, and Justin M Caplan

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Radiofrequency Ablation Provides Rapid and Durable Pain Relief for the Palliative Treatment of Lytic Bone Metastases Independent of Radiation Therapy: Final Results from the OsteoCool Tumor Ablation Post-Market Study., Jason Levy, Elizabeth David, Thomas Hopkins, Jonathan Morris, Nam D Tran, Hamed Farid, Francesco Massari, William G O'Connell, Alexander Vogel, Afshin Gangi, Peter Sunenshine, Robert Dixon, Nicolas Von der Höh, and Sandeep Bagla

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Association of Autologous Tumor Lysate-Loaded Dendritic Cell Vaccination With Extension of Survival Among Patients With Newly Diagnosed and Recurrent Glioblastoma: A Phase 3 Prospective Externally Controlled Cohort Trial., Linda M Liau, Keyoumars Ashkan, Steven Brem, Jian L Campian, John E Trusheim, Fabio M Iwamoto, David D Tran, George Ansstas, Charles Cobbs, Jason A Heth, Michael E Salacz, Stacy D'Andre, Robert D Aiken, Yaron A Moshel, Joo Y Nam, Clement P Pillainayagam, Stephanie A Wagner, Kevin A Walter, Rekha Chaudhary, Samuel A Goldlust, Ian Y Lee, Daniela A Bota, Heinrich Elinzano, Jai Grewal, Kevin Lillehei, Tom Mikkelsen, Tobias Walbert, Steven Abram, Andrew J Brenner, Matthew G Ewend, Simon Khagi, Darren S Lovick, Jana Portnow, Lyndon Kim, William G Loudon, Nina L Martinez, Reid C Thompson, David E Avigan, Karen L Fink, Francois J Geoffroy, Pierre Giglio, Oleg Gligich, Dietmar Krex, Scott M Lindhorst, Jose Lutzky, Hans-Jörg Meisel, Minou Nadji-Ohl, Lhagva Sanchin, Andrew Sloan, Lynne P Taylor, Julian K Wu, Erin M Dunbar, Arnold B Etame, Santosh Kesari, David Mathieu, David E Piccioni, David S Baskin, Michel Lacroix, Sven-Axel May, Pamela Z New, Timothy J Pluard, Steven A Toms, Victor Tse, Scott Peak, John L Villano, James D Battiste, Paul J Mulholland, Michael L Pearlman, Kevin Petrecca, Michael Schulder, Robert M Prins, Alton L Boynton, and Marnix L Bosch

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Long-term survival after salvage pemetrexed for refractory primary T-cell lymphoma of the CNS., Andy Liu, Huda Alalami, Xuemo Fan, Chirag Patil, Jaya M Gill, Santosh Kesari, and Jethro Hu

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Neuroinflammation: A Modifiable Pathway Linking Obesity, Alzheimer's disease, and Depression., Maria Ly, Gary Z Yu, Ali Mian, Austin Cramer, Somayeh Meysami, David A Merrill, Amjad Samara, Sarah A Eisenstein, Tamara Hershey, Ganesh M Babulal, Eric J Lenze, John C Morris, Tammie L S Benzinger, and Cyrus A Raji

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A prospective multi-center observational study of surgical versus non-surgical management for pituitary apoplexy., Adam N Mamelak, Andrew S Little, Paul A Gardner, João Paulo Almeida, Pablo Recinos, Pranay Soni, Varun R Kshettry, John A Jane, Garni Barkhoudarian, Daniel F Kelly, Robert Dodd, Debraj Mukherjee, Zachary C Gersey, Noriaki Fukuhara, Hiroshi Nishioka, Eui-Hyun Kim, Claude-Fabien Litré, Elliott Sina, Mia W Mazer, Yujie Cui, and Vivien Bonert

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Treatment of adult deformity surgery by orthopedic and neurological surgeons: trends in treatment, techniques, and costs by specialty., Christopher L McDonald, Rodrigo A Saad Berreta, Daniel Alsoof, Alex Homer, Janine Molino, Christopher P Ames, Christopher I Shaffrey, D Kojo Hamilton, Bassel G Diebo, Eren O Kuris, Robert A Hart, and Alan H Daniels

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A combined exercise and cognitive training intervention induces fronto-cingulate cortical plasticity in first-episode psychosis patients., S C McEwen, B Jarrahi, J Ventura, K L Subotnik, J Nguyen, S M Woo, and K H Nuechterlein

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Novel TCF4:TCF12 heterodimer inhibits glioblastoma growth., Svetlana A Mikheeva, Cory C Funk, Philip J Horner, Robert C Rostomily, and Andrei M Mikheev

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Clinical Practice Panel: Stand by Me: Using an Enhanced Recovery After Surgery (ERAS)Checklist to Guide Early Mobility of Postoperative Craniotomy Patients on a Progressive Care Unit, Alyssa Mooney, Jerome Codilla, Joanna Arraiza, Sohl Chapman, Nkiru Chukwudi, and Ronald Rosales

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Stereotactic and Functional Neurosurgery Convection-Enhanced Delivery of Autologous Cerebrospinal Fluid Enhances Basal Ganglia Visualization during MRI-Guided Deep Brain Stimulation Surgery., Shayan Moosa, Aaron E Bond, Tony R Wang, Faraz Farzad, Ashok R Asthagiri, and W Jeffrey Elias

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Preliminary experience with a novel facet-based lateral mass drill guide for the placement of lateral mass screws compared to freehand technique: a cadaveric study., Gregory M Mundis, Eric C Olsson, Robert A Hart, Seth K Williams, Ryan Martyn, Douglas G Orndorff, Anastasia L Berg, Nicholas A Russell, and Frank Vizesi

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External Validation of an Artificial Intelligence Device for Intracranial Hemorrhage Detection., Gabriel Neves, Pranav I Warman, Anmol Warman, Roshan Warman, Tulio Bueso, Jason D Vadhan, and Thomas Windisch

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Optimum duration of hyperventilation during electroencephalography., Kalarickal J Oommen and Jonathan Kopel

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Mechanical Venous Thrombectomy Using Indigo Aspiration System: A Case Report., Riichi A Ota, Gabriel Neves, Victor C Montalvan, Thomas Windisch, and Saif Bushnaq

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The impact of baseline cervical malalignment on the development of proximal junctional kyphosis following surgical correction of thoracolumbar adult spinal deformity., Lara Passfall, Bailey Imbo, Virginie Lafage, Renaud Lafage, Justin S Smith, Breton Line, Andrew J Schoenfeld, Themistocles Protopsaltis, Alan H Daniels, Khaled M Kebaish, Jeffrey L Gum, Heiko Koller, D Kojo Hamilton, Richard Hostin, Munish Gupta, Neel Anand, Christopher P Ames, Robert Hart, Douglas Burton, Frank J Schwab, Christopher I Shaffrey, Eric O Klineberg, Han Jo Kim, Shay Bess, and Peter G Passias

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Economic burden of nonoperative treatment of adult spinal deformity., Peter G Passias, Waleed Ahmad, Pooja Dave, Renaud Lafage, Virginie Lafage, Jamshaid Mir, Eric O Klineberg, Khaled M Kabeish, Jeffrey L Gum, Breton G Line, Robert A Hart, Douglas Burton, Justin S Smith, Christopher P Ames, Christopher I Shaffrey, Frank Schwab, Richard Hostin, Thomas Buell, D Kojo Hamilton, and Shay Bess

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Identifying Subsets of Patients With Adult Spinal Deformity Who Maintained a Positive Response to Nonoperative Management., Peter G Passias, Waleed Ahmad, Peter Tretiakov, Oscar Krol, Frank Segreto, Renaud Lafage, Virginie Lafage, Alex Soroceanu, Alan Daniels, Jeffrey Gum, Breton Line, Andrew J Schoenfeld, Shaleen Vira, Robert Hart, Douglas Burton, Justin S Smith, Christopher P Ames, Christopher Shaffrey, Frank Schwab, Shay Bess, and International Spine Study Group

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Critical Analysis of Radiographic and Patient Reported Outcomes Following Anterior/Posterior Staged vs. Same Day Surgery in Patients Undergoing Identical Corrective Surgery for Adult Spinal Deformity., Peter G Passias, Waleed Ahmad, Peter S Tretiakov, Renaud Lafage, Virginie Lafage, Andrew J Schoenfeld, Breton Line, Alan Daniels, Jamshaid M Mir, Munish Gupta, Gregory Mundis, Robert Eastlack, Pierce Nunley, D Kojo Hamilton, Richard Hostin, Robert Hart, Douglas C Burton, Christopher Shaffrey, Frank Schwab, Christopher Ames, Justin S Smith, Shay Bess, Eric O Klineberg, and International Spine Study Group

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Efficacy of Varying Surgical Approaches on Achieving Optimal Alignment in Adult Spinal Deformity Surgery., Peter G Passias, Waleed Ahmad, Tyler K Williamson, Jordan Lebovic, Khaled Kebaish, Renaud Lafage, Virginie Lafage, Breton Line, Andrew J Schoenfeld, Bassel G Diebo, Eric O Klineberg, Han Jo Kim, Christopher P Ames, Alan H Daniels, Justin S Smith, Christopher I Shaffrey, Douglas C Burton, Robert A Hart, Shay Bess, Frank J Schwab, Munish C Gupta, and International Spine Study Group

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Incremental benefits of circumferential minimally invasive surgery for increasingly frail patients with adult spinal deformity., Peter G Passias, Peter S Tretiakov, Pierce D Nunley, Michael Y Wang, Paul Park, Adam S Kanter, David O Okonkwo, Robert K Eastlack, Gregory M Mundis, Dean Chou, Nitin Agarwal, Richard G Fessler, Juan S Uribe, Neel Anand, Khoi D Than, Gregory Brusko, Kai-Ming Fu, Jay D Turner, Vivian P Le, Breton G Line, Christopher P Ames, Justin S Smith, Christopher I Shaffrey, Robert A Hart, Douglas Burton, Renaud Lafage, Virginie Lafage, Frank Schwab, Shay Bess, and Praveen V Mummaneni

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Are We Focused on the Wrong Early Postoperative Quality Metrics? Optimal Realignment Outweighs Perioperative Risk in Adult Spinal Deformity Surgery., Peter G Passias, Tyler K Williamson, Jamshaid M Mir, Justin S Smith, Virginie Lafage, Renaud Lafage, Breton Line, Alan H Daniels, Jeffrey L Gum, Andrew J Schoenfeld, David Kojo Hamilton, Alex Soroceanu, Justin K Scheer, Robert Eastlack, Gregory M Mundis, Bassel Diebo, Khaled M Kebaish, Richard A Hostin, Munish C Gupta, Han Jo Kim, Eric O Klineberg, Christopher P Ames, Robert A Hart, Douglas C Burton, Frank J Schwab, Christopher I Shaffrey, Shay Bess, and On Behalf Of The International Spine Study Group

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Proximal Internal Carotid Artery Occlusion and Extracranial-Intracranial Bypass for Treatment of Fusiform and Giant Internal Carotid Artery Aneurysms., Sophie M Peeters, Geoffrey P Colby, Wi Jin Kim, Whi Inh Bae, Hiro Sparks, Kara Reitz, Satoshi Tateshima, Reza Jahan, Viktor Szeder, May Nour, Gary R Duckwiler, Fernando Vinuela, Neil A Martin, and Anthony C Wang

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Reply to American Society of Transplant Surgeons Recommendations on Best Practices in Donation After Circulatory Death Organ Procurement "Questions on Best Practices in DCD"., Harry Peled and James Bernat

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Intravenous Administration of Umbilical Cord-Derived Mesenchymal Stem Cells (UC-MSC) for Acute Respiratory Distress Syndrome Due to COVID-19 Infection., Jesus A Perez, Juan J Parcero Valdes, Ruben Corral Moreno, Leonardo I Gomez Cuevas, Jose J Lopez, Thomas Ichim, Kristen McGreevy, Feng Lin, Santosh Kesari, and Souvik Datta

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Long-term efficacy of high-frequency (10 kHz) spinal cord stimulation for the treatment of painful diabetic neuropathy: 24-Month results of a randomized controlled trial., Erika A Petersen, Thomas G Stauss, James A Scowcroft, Michael J Jaasma, Elizabeth S Brooks, Deborah R Edgar, Judith L White, Shawn M Sills, Kasra Amirdelfan, Maged N Guirguis, Jijun Xu, Cong Yu, Ali Nairizi, Denis G Patterson, Kostandinos C Tsoulfas, Michael J Creamer, Vincent Galan, Richard H Bundschu, Neel D Mehta, Dawood Sayed, Shivanand P Lad, David J DiBenedetto, Khalid A Sethi, Johnathan H Goree, Matthew T Bennett, Nathan J Harrison, Atef F Israel, Paul Chang, Paul W Wu, Charles E Argoff, Christian E Nasr, Rod S Taylor, David L Caraway, and Nagy A Mekhail

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A Survey on Monitoring and Management of Cerebral Vasospasm and Delayed Cerebral Ischemia After Subarachnoid Hemorrhage: The Mantra Study., Edoardo Picetti, Pierre Bouzat, Mary Kay Bader, Giuseppe Citerio, Raimund Helbok, Janneke Horn, Robert Loch Macdonald, Victoria McCredie, Geert Meyfroidt, Cássia Righy, Chiara Robba, Deepak Sharma, Wade S Smith, Jose I Suarez, Andrew Udy, Stefan Wolf, and Fabio S Taccone

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Exploring the role of cerebrospinal fluid as analyte in neurologic disorders., Sandeep C Pingle, Feng Lin, Misa S Anekoji, C Pawan K Patro, Souvik Datta, Lawrence D Jones, Santosh Kesari, and Shashaanka Ashili

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Emotion regulation and the salience network: a hypothetical integrative model of fibromyalgia., Ana Margarida Pinto, Rinie Geenen, Tor D Wager, Mark A Lumley, Winfried Häuser, Eva Kosek, Jacob N Ablin, Kirstine Amris, Jaime Branco, Dan Buskila, João Castelhano, Miguel Castelo-Branco, Leslie J Crofford, Mary-Ann Fitzcharles, Marina López-Solà, Mariana Luís, Tiago Reis Marques, Philip J Mease, Filipe Palavra, Jamie L Rhudy, Lucina Q Uddin, Paula Castilho, Johannes W G Jacobs, and José A P da Silva

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Reply to 'Imbalance of threat and soothing systems in fibromyalgia: rephrasing an established mechanistic model?'., Ana Margarida Pinto, Rinie Geenen, Tor D Wager, Mark A Lumley, Winfried Häuser, Eva Kosek, Jacob N Ablin, Kirstine Amris, Jaime Branco, Dan Buskila, João Castelhano, Miguel Castelo-Branco, Leslie J Crofford, Mary-Ann Fitzcharles, Marina López-Solà, Mariana Luís, Tiago Reis Marques, Philip Mease, Filipe Palavra, Jamie L Rhudy, Lucina Q Uddin, Paula Castilho, Johannes W G Jacobs, and José A P da Silva

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Neurophysiological and psychosocial mechanisms of fibromyalgia: A comprehensive review and call for an integrative model., Ana Margarida Pinto, Mariana Luís, Rinie Geenen, Filipe Palavra, Mark A Lumley, Jacob N Ablin, Kirstine Amris, Jaime Branco, Dan Buskila, João Castelhano, Miguel Castelo-Branco, Leslie J Crofford, Mary-Ann Fitzcharles, Winfried Häuser, Eva Kosek, Philip J Mease, Tiago Reis Marques, Johannes W G Jacobs, Paula Castilho, and José A P da Silva

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A novel scoring system concept for de novo spinal infection treatment, the Spinal Infection Treatment Evaluation Score (SITE Score): a proof-of-concept study., Jonathan Pluemer, Yevgeniy Freyvert, Nathan Pratt, Jerry E Robinson, Jared A Cooke, Zachary L Tataryn, Clifford A Pierre, Periklis Godolias, Sven Frieler, Alexander von Glinski, Emre Yilmaz, Zeyad A Daher, Hamzah A Al-Awadi, Mitchell H Young, Rod J Oskouian, and Jens R Chapman

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Clinical outcomes and proximal junctional failure in adult spinal deformity patients corrected to normative alignment versus functional alignment., Themistocles S Protopsaltis, Fares Ani, Alexandra Soroceanu, Renaud Lafage, Han Jo Kim, Eaman Balouch, Zoe Norris, Justin S Smith, Alan H Daniels, Eric O Klineberg, Christopher P Ames, Robert Hart, Shay Bess, Christopher I Shaffrey, Frank J Schwab, Lawrence G Lenke, Virginie Lafage, and Munish C Gupta

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Single-Dose Psilocybin Treatment for Major Depressive Disorder: A Randomized Clinical Trial., Charles L Raison, Gerard Sanacora, Joshua Woolley, Keith Heinzerling, Boadie W Dunlop, Randall T Brown, Rishi Kakar, Michael Hassman, Rupal P Trivedi, Reid Robison, Natalie Gukasyan, Sandeep M Nayak, Xiaojue Hu, Kelley C O'Donnell, Benjamin Kelmendi, Jordan Sloshower, Andrew D Penn, Ellen Bradley, Daniel F Kelly, Tanja Mletzko, Christopher R Nicholas, Paul R Hutson, Gary Tarpley, Malynn Utzinger, Kelsey Lenoch, Kasia Warchol, Theraysa Gapasin, Mike C Davis, Courtney Nelson-Douthit, Steffanie Wilson, Carrie Brown, William Linton, Stephen Ross, and Roland R Griffiths

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Visceral and Subcutaneous Abdominal Fat Predict Brain Volume Loss at Midlife in 10,001 Individuals., Cyrus A Raji, Somayeh Meysami, Sam Hashemi, Saurabh Garg, Nasrin Akbari, Ahmed Gouda, Yosef Gavriel Chodakiewitz, Thanh Duc Nguyen, Kellyann Niotis, David A Merrill, and Rajpaul Attariwala

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Cancer stem cell assay-guided chemotherapy improves survival of patients with recurrent glioblastoma in a randomized trial., Tulika Ranjan, Soma Sengupta, Michael J Glantz, Richard M Green, Alexander Yu, Dawit Aregawi, Rekha Chaudhary, Ricky Chen, Mario Zuccarello, Christine Lu-Emerson, Hugh D Moulding, Neil Belman, Jon Glass, Aaron Mammoser, Mark Anderson, Jagan Valluri, Nicholas Marko, Jason Schroeder, Steven Jubelirer, Frances Chow, Pier Paolo Claudio, Anthony M Alberico, Seth T Lirette, Krista L Denning, and Candace M Howard

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Association between Cannabis Use and Tinnitus in US Adults., Francis Reyes Orozco, Matthew Lin, Bhavishya Clark, Joni K Doherty, John S Oghalai, Courtney C J Voelker, and Janet S Choi

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Bimekizumab treatment in biologic DMARD-naïve patients with active psoriatic arthritis: 52-week efficacy and safety results from the phase III, randomised, placebo-controlled, active reference BE OPTIMAL study., Christopher T Ritchlin, Laura C Coates, Iain B McInnes, Philip Mease, Joseph F Merola, Yoshiya Tanaka, Akihiko Asahina, Laure Gossec, Alice B Gottlieb, Richard B Warren, Barbara Ink, Rajan Bajracharya, Vishvesh Shende, Jason Coarse, and Robert Bm Landewé

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Embolization as stand-alone strategy for pediatric low-grade brain arteriovenous malformations., Aaron Rodriguez-Calienes, Juan Vivanco-Suarez, Matias Costa, Johssy Yelma Echevarria-Quispe, Rodolfo Rodríguez-Varela, Santiago Ortega-Gutierrez, and Giancarlo Saal-Zapata

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Polyclonal lymphoid expansion drives paraneoplastic autoimmunity in neuroblastoma., Miriam I Rosenberg, Erez Greenstein, Martin Buchkovich, Ayelet Peres, Eric Santoni-Rugiu, Lei Yang, Martin Mikl, Zalman Vaksman, David L Gibbs, Dan Reshef, Amy Salovin, Meredith S Irwin, Arlene Naranjo, Igor Ulitsky, Pedro A de Alarcon, Katherine K Matthay, Victor Weigman, Gur Yaari, Jessica A Panzer, Nir Friedman, and John M Maris

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Immunotherapy responsiveness and risk of relapse in Down syndrome regression disorder., Jonathan D Santoro, Noemi A Spinazzi, Robyn A Filipink, Panteha Hayati-Rezvan, Ryan Kammeyer, Lina Patel, Elise A Sannar, Luke Dwyer, Abhik K Banerjee, Mellad Khoshnood, Saba Jafarpour, Natalie K Boyd, Rebecca Partridge, Grace Y Gombolay, Alison Christy, Diego Real de Asua, Maria Del Carmen Ortega, Melanie A Manning, Heather Van Mater, Gordan Worley, Cathy Franklin, Maria A Stanley, Ruth Brown, George T Capone, Eileen A Quinn, and Michael S Rafii

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Remission of severe myasthenia gravis after autologous stem cell transplantation., Monica I Schlatter, Soumya S Yandamuri, Kevin C O'Connor, Richard J Nowak, Minh C Pham, Abeer H Obaid, Callee Redman, Marie Provost, Peter A McSweeney, Michael L Pearlman, Michael T Tees, J D Bowen, Richard A Nash, and George E Georges

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Comprehensive Understanding of Hispanic Caregivers: Focus on Innovative Methods and Validations., Ujala Sehar, Priyanka Rawat, Moumita Choudhury, Annette Boles, John Culberson, Hafiz Khan, Keya Malhotra, Tanisha Basu, and P Hemachandra Reddy

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Letter to the editor regarding "Vascular anomalies in patients with growth hormone-secreting pituitary adenomas: illustrative case report and systematic review of the literature"., Walavan Sivakumar and William T Couldwell

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Evaluating the efficacy and safety of transitioning patients with multiple sclerosis from natalizumab to ocrelizumab (OCTAVE)., Kyle Smoot, Horia Marginean, Tiffany Gervasi-Follmar, Chiayi Chen, Pavle Repovic, and Stanley Cohan

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Processing speed and memory test performance are associated with different brain region volumes in Veterans and others with progressive multiple sclerosis., Rebecca I Spain, Andrea Hildebrand, Carin S Waslo, William D Rooney, Joshua Emmons, Daniel L Schwartz, Mark S Freedman, M Mateo Paz Soldan, Pavle Repovic, Andrew J Solomon, John Rinker, Mitchell Wallin, Jodie K Haselkorn, Olaf Stuve, Robert H Gross, and Aaron P Turner

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Association of age and inflammatory disease activity in the pivotal natalizumab clinical trials in relapsing-remitting multiple sclerosis., Eva M Strijbis, Eline Coerver, Jop Mostert, Zoé L E van Kempen, Joep Killestein, Jacynthe Comtois, Pavle Repovic, James D Bowen, Gary Cutter, and Marcus Koch

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ALSUntangled #71: Nuedexta., Yuyao Sun, Michael Benatar, Javier Mascías Cadavid, Dave Ennist, Paul Wicks, Kim Staats, Morgan Beauchamp, Sartaj Jhooty, Gary Pattee, Andrew Brown, Tulio Bertorini, Paul Barkhaus, Mark Bromberg, Greg Carter, Richard Bedlack, and Xiaoyan Li

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Biological functions of the Olig gene family in brain cancer and therapeutic targeting., Jenny Szu, Igor F Tsigelny, Alexandre Wojcinski, and Santosh Kesari

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Keynote: Escaping a Code Stroke: Impact of Escape Room Methodology on Nurses’ Attitudes towards Acute Stroke Management Guidelines, Diana D. Tai

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Clinical Outcomes of Stereotactic Radiosurgery-Related Radiation Necrosis in Patients with Intracranial Metastasis from Melanoma., Holly M Thomson, Shannon P Fortin Ensign, Victoria S Edmonds, Akanksha Sharma, Richard J Butterfield, Steven E Schild, Jonathan B Ashman, Richard S Zimmerman, Naresh P Patel, Alan H Bryce, Sujay A Vora, Terence T Sio, and Alyx B Porter

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Guidelines for the Neurocritical Care Management of Aneurysmal Subarachnoid Hemorrhage., Miriam M Treggiari, Alejandro A Rabinstein, Katharina M Busl, Meghan M Caylor, Giuseppe Citerio, Steven Deem, Michael Diringer, Elizabeth Fox, Sarah Livesay, Kevin N Sheth, Jose I Suarez, and Stavropoula Tjoumakaris

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Calibration of a comprehensive predictive model for the development of proximal junctional kyphosis and failure in adult spinal deformity patients with consideration of contemporary goals and techniques., Peter S Tretiakov, Renaud Lafage, Justin S Smith, Breton G Line, Bassel G Diebo, Alan H Daniels, Jeffrey Gum, Themistocles Protopsaltis, D Kojo Hamilton, Alex Soroceanu, Justin K Scheer, Robert K Eastlack, Gregory Mundis, Pierce D Nunley, Eric O Klineberg, Khaled Kebaish, Stephen Lewis, Lawrence Lenke, Richard Hostin, Munish C Gupta, Christopher P Ames, Robert A Hart, Douglas Burton, Christopher I Shaffrey, Frank Schwab, Shay Bess, Han Jo Kim, Virginie Lafage, and Peter G Passias

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Posterior cervical congenital dermal sinus tract: case report and review of literature., Amir Vokshoor, Harseerat Jajj, Tiffany Grunwald, Steven E Kolker, and Jack Petros

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The ISSG-AO Complication Intervention Score, but Not Major/Minor Designation, is Correlated With Length of Stay Following Adult Spinal Deformity Surgery., Joseph B Wick, Andrew Blandino, Justin S Smith, Breton G Line, Virginie Lafage, Renaud Lafage, Han Jo Kim, Peter G Passias, Jeffrey L Gum, Khaled M Kebaish, Robert K Eastlack, Alan Daniels, Gregory Mundis, Richard Hostin, Themistocles Protopsaltis, D Kojo Hamilton, Michael P Kelly, Munish Gupta, Robert A Hart, Frank J Schwab, Douglas C Burton, Christopher P Ames, Lawrence G Lenke, Christopher I Shaffrey, Shay Bess, Eric Klineberg, and International Spine Study Group

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Real-World Safety and Effectiveness After 5 Years of Dimethyl Fumarate Treatment in Black and Hispanic Patients with Multiple Sclerosis in ESTEEM., Mitzi J Williams, Lilyana Amezcua, Angel Chinea, Stanley Cohan, Annette Okai, Darin T Okuda, Wendy Vargas, Nick Belviso, Ivan Božin, Xiaotong Jiang, James B Lewin, Jennifer Lyons, Changyu Shen, Sarah M England, and Nydjie Grimes

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Hypothermia is associated with improved neurological outcomes after mechanical thrombectomy., Risheng Xu, Sumil K Nair, Collin B Kilgore, Michael E Xie, Christopher M Jackson, Ferdinand Hui, Phillipe Gailloud, Cameron G McDougall, L Fernando Gonzalez, Judy Huang, Rafael J Tamargo, and Justin Caplan

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Diagnostics of ovarian cancer via metabolite analysis and machine learning., Jerry Z Yao, Igor F Tsigelny, Santosh Kesari, and Valentina L Kouznetsova

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Use of multiple rods and proximal junctional kyphosis in adult spinal deformity surgery., Jichao Ye, Sachin Gupta, Ali S Farooqi, Tsung-Cheng Yin, Alex Soroceanu, Frank J Schwab, Virginie Lafage, Michael P Kelly, Khaled Kebaish, Richard Hostin, Jeffrey L Gum, Justin S Smith, Christopher I Shaffrey, Justin K Scheer, Themistocles S Protopsaltis, Peter G Passias, Eric O Klineberg, Han Jo Kim, Robert A Hart, D Kojo Hamilton, Christopher P Ames, and Munish C Gupta

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Cost-effectiveness Analysis of Inferior Turbinate Reduction and Immunotherapy in Allergic Rhinitis., Michael Yong, Kaishan Aravinthan, Keshinisuthan Kirubalingam, Andrew Thamboo, Peter H Hwang, Kari Nadeau, and Evan Walgama

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Therapy of autoimmune inflammation in sporadic amyotrophic lateral sclerosis: Dimethyl fumarate and H-151 downregulate inflammatory cytokines in the cGAS-STING pathway., Kurosh Zamiri, Santosh Kesari, Ketema Paul, Sung Hee Hwang, Bruce Hammock, Karolina Elżbieta Kaczor-Urbanowicz, Andrzej Urbanowicz, Lucy Gao, Julian Whitelegge, and Milan Fiala

Submissions from 2022

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Effects of Cervical Spine Exercise Protocol on Neck Pain, Pericervical Muscle Endurance, and Range of Motion in Medical Students: A Prospective Study., Bryan G Anderson, Brett Benzinger, Jason Chickness, Chris Hietanen, Kylan Hill, Jean-Marc P Lucas, Joshua Tuck, and Michael Ghassibi

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HIV Antiretroviral Medication Neuropenetrance and Neurocognitive Outcomes in HIV+ Adults: A Review of the Literature Examining the Central Nervous System Penetration Effectiveness Score., Alyssa Arentoft, Katie Troxell, Karen Alvarez, Maral Aghvinian, Monica Rivera Mindt, Mariana Cherner, Kathleen Van Dyk, Jill Razani, Michaela Roxas, and Melissa Gavilanes

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HIV Antiretroviral Medication Neuropenetrance and Neurocognitive Outcomes in HIV+ Adults: A Review of the Literature Examining the Central Nervous System Penetration Effectiveness Score., Alyssa Arentoft, Katie Troxell, Karen Alvarez, Maral Aghvinian, Monica Rivera Mindt, Mariana Cherner, Kathleen Van Dyk, Jill Razani, Michaela Roxas, and Melissa Gavilanes

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Transplantation of human neural progenitor cells secreting GDNF into the spinal cord of patients with ALS: a phase 1/2a trial., Robert H Baloh, J Patrick Johnson, Pablo Avalos, Peggy Allred, Soshana Svendsen, Genevieve Gowing, Kristina Roxas, Amanda Wu, Becky Donahue, Sheryl Osborne, George Lawless, Brandon Shelley, Koral Wheeler, Carolyn Prina, Dana Fine, Tami Kendra-Romito, Haniah Stokes, Vicki Manoukian, Abirami Muthukumaran, Leslie Garcia, Maria G Bañuelos, Marlesa Godoy, Catherine Bresee, Hong Yu, Doniel Drazin, Lindsey Ross, Robert Naruse, Harish Babu, Eric A Macklin, Ashley Vo, Ashraf Elsayegh, Warren Tourtellotte, Marcel Maya, Matthew Burford, Frank Diaz, Chirag G Patil, Richard A Lewis, and Clive N Svendsen